Ejercicio R de PCR
Los chunks los obtengo con: Cmd + Opt+ I
PaqueterÃa
#install.packages("pacman")
library("pacman")
#pacman llama a otros paquetes y si no estan los instala
p_load("vroom", #llamar bases de datos
"dplyr", #facilita el manejo de datos
"ggplot2") #graficar
Llamar base de datos
Datos_PCR <- #correr datos
vroom(file = "https://raw.githubusercontent.com/ManuelLaraMVZ/Metabolomica_2026_1/refs/heads/main/Datos_ejercicio_PCR1.1.csv")
## Rows: 1001 Columns: 7
## ── Column specification ────────────────────────────────────────────────────────
## Delimiter: ","
## chr (1): Gen
## dbl (6): C1, C2, C3, T1, T2, T3
##
## ℹ Use `spec()` to retrieve the full column specification for this data.
## ℹ Specify the column types or set `show_col_types = FALSE` to quiet this message.
Datos_PCR
## # A tibble: 1,001 × 7
## Gen C1 C2 C3 T1 T2 T3
## <chr> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl>
## 1 B-actina 19.9 20.2 19.9 20.0 20.1 19.9
## 2 Gene_1 23.9 23.0 24.0 21.7 22.4 21.0
## 3 Gene_2 24.5 22.9 25.5 21.3 23.3 24.3
## 4 Gene_3 28.1 25.0 23.9 19.1 23.3 19.7
## 5 Gene_4 25.1 24.7 27.4 20.6 19.4 25.0
## 6 Gene_5 25.3 19.9 25.3 27.2 17.9 23.8
## 7 Gene_6 28.4 27.1 23.8 21.9 26.4 22.7
## 8 Gene_7 25.9 25.5 21.4 23.8 22.5 23.1
## 9 Gene_8 22.5 29.8 23.7 21.6 22.8 22.4
## 10 Gene_9 23.6 26.4 29.1 23.2 19.6 21.1
## # ℹ 991 more rows
Aislar gen de referencia
Gen_ref <- Datos_PCR %>% # a la base de datos PCR le haras lo siguiuente
filter(Gen == "B-actina")#seleccionar filas; == exactamente igual/identico
Gen_ref
## # A tibble: 1 × 7
## Gen C1 C2 C3 T1 T2 T3
## <chr> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl>
## 1 B-actina 19.9 20.2 19.9 20.0 20.1 19.9
Gen de intéres
Gen_int <- Datos_PCR %>%
filter(Gen !="B-actina") # !: todos excepto
Gen_int
## # A tibble: 1,000 × 7
## Gen C1 C2 C3 T1 T2 T3
## <chr> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl>
## 1 Gene_1 23.9 23.0 24.0 21.7 22.4 21.0
## 2 Gene_2 24.5 22.9 25.5 21.3 23.3 24.3
## 3 Gene_3 28.1 25.0 23.9 19.1 23.3 19.7
## 4 Gene_4 25.1 24.7 27.4 20.6 19.4 25.0
## 5 Gene_5 25.3 19.9 25.3 27.2 17.9 23.8
## 6 Gene_6 28.4 27.1 23.8 21.9 26.4 22.7
## 7 Gene_7 25.9 25.5 21.4 23.8 22.5 23.1
## 8 Gene_8 22.5 29.8 23.7 21.6 22.8 22.4
## 9 Gene_9 23.6 26.4 29.1 23.2 19.6 21.1
## 10 Gene_10 24.1 24.1 23.9 21.9 24.3 21.3
## # ℹ 990 more rows
Analisis
DCT <- Gen_int %>%
mutate(DCTC1= C1- Gen_ref$C1,
DCTC2= C2 - Gen_ref$C2,
DCTC3= C3 - Gen_ref$C3,
DCTT1= T1 - Gen_ref$T1,
DCTT2= T2 - Gen_ref$T2,
DCTT3= T3 - Gen_ref$T3) %>%
mutate(DosDCT_C1=2^-DCTC1,
DosDCT_C2=2^-DCTC2,
DosDCT_C3=2^-DCTC3,
DosDCT_T1=2^-DCTT1,
DosDCT_T2=2^-DCTT2,
DosDCT_T3=2^-DCTT3) %>%
mutate(DosDCT_Cx_prom = (DosDCT_C1+DosDCT_C2+DosDCT_C3)/3,
DosDCT_Tx_prom = (DosDCT_T1+DosDCT_T2+DosDCT_T3)/3)%>%
mutate (DosDDCT= DosDCT_Tx_prom/DosDCT_Cx_prom)
DCT
## # A tibble: 1,000 × 22
## Gen C1 C2 C3 T1 T2 T3 DCTC1 DCTC2 DCTC3 DCTT1 DCTT2
## <chr> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl>
## 1 Gene_1 23.9 23.0 24.0 21.7 22.4 21.0 4.02 2.81 4.12 1.72 2.27
## 2 Gene_2 24.5 22.9 25.5 21.3 23.3 24.3 4.68 2.72 5.61 1.37 3.18
## 3 Gene_3 28.1 25.0 23.9 19.1 23.3 19.7 8.26 4.76 4.06 -0.876 3.22
## 4 Gene_4 25.1 24.7 27.4 20.6 19.4 25.0 5.28 4.54 7.58 0.626 -0.689
## 5 Gene_5 25.3 19.9 25.3 27.2 17.9 23.8 5.40 -0.298 5.49 7.22 -2.17
## 6 Gene_6 28.4 27.1 23.8 21.9 26.4 22.7 8.57 6.88 3.91 1.95 6.29
## 7 Gene_7 25.9 25.5 21.4 23.8 22.5 23.1 6.06 5.30 1.52 3.85 2.34
## 8 Gene_8 22.5 29.8 23.7 21.6 22.8 22.4 2.61 9.63 3.85 1.65 2.63
## 9 Gene_9 23.6 26.4 29.1 23.2 19.6 21.1 3.77 6.17 9.23 3.24 -0.507
## 10 Gene_10 24.1 24.1 23.9 21.9 24.3 21.3 4.25 3.91 4.02 1.92 4.14
## # ℹ 990 more rows
## # ℹ 10 more variables: DCTT3 <dbl>, DosDCT_C1 <dbl>, DosDCT_C2 <dbl>,
## # DosDCT_C3 <dbl>, DosDCT_T1 <dbl>, DosDCT_T2 <dbl>, DosDCT_T3 <dbl>,
## # DosDCT_Cx_prom <dbl>, DosDCT_Tx_prom <dbl>, DosDDCT <dbl>
Seleccion de datos para graficar
Datos_grafica <- DCT %>%
select("Gen","DosDDCT")
Datos_grafica
## # A tibble: 1,000 × 2
## Gen DosDDCT
## <chr> <dbl>
## 1 Gene_1 3.69
## 2 Gene_2 2.59
## 3 Gene_3 30.6
## 4 Gene_4 30.9
## 5 Gene_5 3.59
## 6 Gene_6 5.36
## 7 Gene_7 0.955
## 8 Gene_8 2.79
## 9 Gene_9 21.9
## 10 Gene_10 3.82
## # ℹ 990 more rows
Gráfica
Grafica_PCR <- ggplot(Datos_grafica,
aes(x = Gen,
y = DosDDCT)) + # fill por Gen para colores distintos
geom_col() +
labs(title = "Expresión relativa de genes",
subtitle = "Normalización con B-actina como referencia",
caption = "Diseño: XXXX") +
theme_minimal(base_size = 14) + # estilo minimalista
theme(plot.background = element_rect(fill = "white", color = NA),
panel.background = element_rect(fill = "white", color = NA)) +
scale_fill_brewer(palette = "Set3") # paleta con colores distintos
Grafica_PCR
Análisis de regresión lineal
Datos_regresion <- DCT %>%
select("Gen","DosDCT_Cx_prom", "DosDCT_Tx_prom")
Datos_regresion
## # A tibble: 1,000 × 3
## Gen DosDCT_Cx_prom DosDCT_Tx_prom
## <chr> <dbl> <dbl>
## 1 Gene_1 0.0874 0.322
## 2 Gene_2 0.0704 0.182
## 3 Gene_3 0.0334 1.02
## 4 Gene_4 0.0247 0.763
## 5 Gene_5 0.425 1.53
## 6 Gene_6 0.0259 0.139
## 7 Gene_7 0.129 0.123
## 8 Gene_8 0.0781 0.218
## 9 Gene_9 0.0297 0.651
## 10 Gene_10 0.0603 0.231
## # ℹ 990 more rows
Graficar
Grafica_regresion <- ggplot(Datos_regresion,
aes(x = DosDCT_Cx_prom,
y = DosDCT_Tx_prom)) +
geom_point(color = "#e75480", size = 3) +
geom_abline(intercept = 0, slope = 1,
color = "#ff69b4", linetype = "dashed") +
theme_minimal(base_size = 14) +
labs(title = "Comparación de valores ΔΔCT",
subtitle = "Relación entre condiciones Cx y Tx",
x = "ΔΔCT promedio condición control (Cx)",
y = "ΔΔCT promedio condición tratamiento (Tx)",) +
theme(
plot.title = element_text(face = "bold", hjust = 0.5, color = "#c71585"),
plot.subtitle = element_text(hjust = 0.5, color = "#db7093"),
plot.caption = element_text(hjust = 1, color = "#8b008b"))
Grafica_regresion
EstadÃstica para obtener el valor de p (significancia, p<0.05)
Datos_estadistica <- DCT %>%
select(Gen,
DosDCT_C1,
DosDCT_C2,
DosDCT_C3,
DosDCT_T1,
DosDCT_T2,
DosDCT_T3)
Datos_estadistica
## # A tibble: 1,000 × 7
## Gen DosDCT_C1 DosDCT_C2 DosDCT_C3 DosDCT_T1 DosDCT_T2 DosDCT_T3
## <chr> <dbl> <dbl> <dbl> <dbl> <dbl> <dbl>
## 1 Gene_1 0.0617 0.143 0.0577 0.304 0.207 0.456
## 2 Gene_2 0.0390 0.152 0.0204 0.388 0.110 0.0481
## 3 Gene_3 0.00327 0.0368 0.0601 1.83 0.107 1.13
## 4 Gene_4 0.0257 0.0431 0.00524 0.648 1.61 0.0295
## 5 Gene_5 0.0237 1.23 0.0223 0.00672 4.51 0.0645
## 6 Gene_6 0.00263 0.00848 0.0666 0.260 0.0128 0.144
## 7 Gene_7 0.0150 0.0254 0.348 0.0695 0.197 0.104
## 8 Gene_8 0.164 0.00126 0.0693 0.318 0.161 0.173
## 9 Gene_9 0.0735 0.0139 0.00166 0.106 1.42 0.427
## 10 Gene_10 0.0526 0.0667 0.0618 0.265 0.0566 0.370
## # ℹ 990 more rows
Esta es la forma de exportar la tabla
write.csv(Datos_estadistica,"Datos_estadistica.csv")
Prueba estadistica t-student Necesitamos un paquete para los analisis estadisticos matrixTest
#install.packages
p_load(matrixTests) #la función on pload es de pacman y llama el paquete y si no esta lo instala
Hacemos la prueba
#de que base de datos vamos a trabajar?
Prueba_t <-row_t_welch(Datos_estadistica[,c("DosDCT_C1","DosDCT_C2","DosDCT_C3")],
Datos_estadistica[, c("DosDCT_T1","DosDCT_T2","DosDCT_T3")])
Prueba_t
## obs.x obs.y obs.tot mean.x mean.y mean.diff var.x
## 1 3 3 6 0.087355923 0.322137135 -2.347812e-01 2.299812e-03
## 2 3 3 6 0.070384961 0.182233069 -1.118481e-01 5.044252e-03
## 3 3 3 6 0.033399894 1.022962940 -9.895630e-01 8.173820e-04
## 4 3 3 6 0.024684424 0.763222585 -7.385382e-01 3.590981e-04
## 5 3 3 6 0.425142391 1.526940491 -1.101798e+00 4.851453e-01
## 6 3 3 6 0.025908468 0.138912748 -1.130043e-01 1.251306e-03
## 7 3 3 6 0.129295913 0.123430498 5.865416e-03 3.574884e-02
## 8 3 3 6 0.078127003 0.217680387 -1.395534e-01 6.665910e-03
## 9 3 3 6 0.029680241 0.651224487 -6.215442e-01 1.477323e-03
## 10 3 3 6 0.060349330 0.230545936 -1.701966e-01 5.093740e-05
## 11 3 3 6 0.032133791 0.196386220 -1.642524e-01 2.556563e-03
## 12 3 3 6 0.009804423 0.189774207 -1.799698e-01 7.030720e-05
## 13 3 3 6 0.075339531 2.409494850 -2.334155e+00 1.062245e-02
## 14 3 3 6 0.017689731 0.496070876 -4.783811e-01 5.203063e-05
## 15 3 3 6 0.050371171 0.564760965 -5.143898e-01 9.953056e-05
## 16 3 3 6 0.012017710 0.094451051 -8.243334e-02 1.873207e-04
## 17 3 3 6 0.061549679 0.570905157 -5.093555e-01 5.165516e-03
## 18 3 3 6 0.223334420 0.558270891 -3.349365e-01 4.080002e-02
## 19 3 3 6 0.036741808 0.120979437 -8.423763e-02 1.162920e-03
## 20 3 3 6 0.022949620 0.998491696 -9.755421e-01 7.680526e-04
## 21 3 3 6 0.064462399 0.295885476 -2.314231e-01 2.829535e-03
## 22 3 3 6 0.029812160 1.464856527 -1.435044e+00 4.327442e-04
## 23 3 3 6 0.041471548 0.227645066 -1.861735e-01 4.351657e-03
## 24 3 3 6 0.037198322 1.874057591 -1.836859e+00 1.285493e-03
## 25 3 3 6 0.159891229 1.649049089 -1.489158e+00 2.788049e-02
## 26 3 3 6 0.136324954 0.007697327 1.286276e-01 1.961448e-02
## 27 3 3 6 0.017794409 0.012821652 4.972757e-03 4.065893e-04
## 28 3 3 6 0.019746155 0.037163801 -1.741765e-02 1.794814e-04
## 29 3 3 6 0.053079043 0.012503697 4.057535e-02 5.415478e-03
## 30 3 3 6 0.051333264 0.010227166 4.110610e-02 5.369207e-03
## 31 3 3 6 0.111163529 0.010215132 1.009484e-01 7.715072e-03
## 32 3 3 6 0.038780280 0.009467817 2.931246e-02 1.845506e-04
## 33 3 3 6 0.051835450 0.009540145 4.229530e-02 5.158931e-03
## 34 3 3 6 0.028397230 0.025375572 3.021658e-03 1.158727e-03
## 35 3 3 6 0.039611942 0.008074940 3.153700e-02 2.730455e-03
## 36 3 3 6 0.069410294 0.011167624 5.824267e-02 8.168809e-03
## 37 3 3 6 0.022690065 0.014130324 8.559742e-03 7.525802e-05
## 38 3 3 6 0.018710942 0.008940886 9.770055e-03 1.633517e-04
## 39 3 3 6 0.027622685 0.002207703 2.541498e-02 3.673908e-04
## 40 3 3 6 0.031566972 0.001933497 2.963348e-02 6.222816e-04
## 41 3 3 6 0.082990184 0.001567772 8.142241e-02 3.740935e-03
## 42 3 3 6 0.021603095 0.002909372 1.869372e-02 2.016836e-04
## 43 3 3 6 0.161817789 0.002840301 1.589775e-01 1.444809e-02
## 44 3 3 6 0.032185677 0.001010247 3.117543e-02 7.261566e-04
## 45 3 3 6 0.012321617 0.005814253 6.507364e-03 4.600372e-05
## 46 3 3 6 0.113611164 0.015510496 9.810067e-02 2.309451e-03
## 47 3 3 6 0.100684326 0.003428331 9.725600e-02 1.105771e-02
## 48 3 3 6 0.051534109 0.043457923 8.076186e-03 4.458491e-04
## 49 3 3 6 0.030066139 0.003568479 2.649766e-02 1.691858e-03
## 50 3 3 6 0.059245445 0.036379829 2.286562e-02 2.142581e-03
## 51 3 3 6 0.026692544 0.417551315 -3.908588e-01 8.864429e-05
## 52 3 3 6 0.040705580 0.527232013 -4.865264e-01 9.418200e-05
## 53 3 3 6 0.019240255 0.042050441 -2.281019e-02 1.122426e-04
## 54 3 3 6 0.047292083 0.090719174 -4.342709e-02 5.667258e-03
## 55 3 3 6 0.024951444 0.037187059 -1.223562e-02 2.607938e-04
## 56 3 3 6 0.011917430 0.089002275 -7.708484e-02 5.361502e-05
## 57 3 3 6 0.127937247 0.036776386 9.116086e-02 1.142819e-02
## 58 3 3 6 0.019403743 0.040048687 -2.064494e-02 1.441370e-04
## 59 3 3 6 0.019383140 0.123853489 -1.044703e-01 2.996209e-05
## 60 3 3 6 0.019345108 0.031926524 -1.258142e-02 5.901174e-06
## 61 3 3 6 0.009141345 0.027905067 -1.876372e-02 4.403469e-05
## 62 3 3 6 0.084142106 0.308156952 -2.240148e-01 7.475659e-04
## 63 3 3 6 0.018822020 0.019745345 -9.233251e-04 5.182288e-04
## 64 3 3 6 0.047478271 0.043889486 3.588786e-03 3.583955e-03
## 65 3 3 6 0.064120610 0.008747170 5.537344e-02 2.939932e-03
## 66 3 3 6 0.073049910 0.649054864 -5.760050e-01 3.707338e-03
## 67 3 3 6 0.071087187 0.013165533 5.792165e-02 6.356822e-03
## 68 3 3 6 0.020761694 0.076603147 -5.584145e-02 2.456542e-05
## 69 3 3 6 0.181218503 0.021439052 1.597795e-01 7.464267e-02
## 70 3 3 6 0.023352368 0.065493999 -4.214163e-02 1.323803e-03
## 71 3 3 6 0.028570291 0.044301822 -1.573153e-02 5.703587e-04
## 72 3 3 6 0.266476890 0.223407693 4.306920e-02 1.388579e-01
## 73 3 3 6 0.080614970 0.050084389 3.053058e-02 5.039267e-03
## 74 3 3 6 0.074927144 0.010529565 6.439758e-02 3.607166e-05
## 75 3 3 6 0.038798566 0.038098562 7.000045e-04 9.100507e-04
## 76 3 3 6 0.115889523 0.018271499 9.761802e-02 1.960414e-02
## 77 3 3 6 0.022721884 0.101561542 -7.883966e-02 3.021351e-04
## 78 3 3 6 0.261725128 0.039569648 2.221555e-01 7.552718e-02
## 79 3 3 6 0.040211091 0.025220222 1.499087e-02 3.072274e-04
## 80 3 3 6 0.072567973 0.014475887 5.809209e-02 1.144088e-03
## 81 3 3 6 0.063657851 0.018808553 4.484930e-02 7.165214e-03
## 82 3 3 6 0.055251936 0.024366407 3.088553e-02 3.816739e-03
## 83 3 3 6 0.031182297 0.022562379 8.619919e-03 2.065828e-04
## 84 3 3 6 0.139873132 0.017713588 1.221595e-01 4.140525e-02
## 85 3 3 6 0.031986058 0.155150388 -1.231643e-01 2.378479e-04
## 86 3 3 6 0.291589575 0.039561188 2.520284e-01 1.346536e-01
## 87 3 3 6 0.102565427 0.098688973 3.876455e-03 7.708353e-03
## 88 3 3 6 0.019872008 0.017483800 2.388209e-03 1.583754e-04
## 89 3 3 6 0.069219227 0.218293904 -1.490747e-01 6.616343e-04
## 90 3 3 6 0.165484598 0.015627281 1.498573e-01 4.462603e-02
## 91 3 3 6 0.005621987 0.104517965 -9.889598e-02 4.897173e-06
## 92 3 3 6 0.334734796 0.034314649 3.004201e-01 3.014428e-01
## 93 3 3 6 0.052419572 0.123876213 -7.145664e-02 3.497916e-03
## 94 3 3 6 0.043618313 0.050941680 -7.323367e-03 9.560983e-04
## 95 3 3 6 0.044161038 0.037977406 6.183632e-03 1.673573e-03
## 96 3 3 6 0.052487836 0.014546903 3.794093e-02 8.369720e-04
## 97 3 3 6 0.042973465 0.143354511 -1.003810e-01 3.257033e-03
## 98 3 3 6 0.014123174 0.059635252 -4.551208e-02 2.076823e-04
## 99 3 3 6 0.022607857 0.037768084 -1.516023e-02 2.262981e-04
## 100 3 3 6 0.062931671 0.028244954 3.468672e-02 2.468242e-03
## 101 3 3 6 0.041160753 0.011578889 2.958186e-02 1.094634e-03
## 102 3 3 6 0.016091087 0.089427928 -7.333684e-02 1.634032e-05
## 103 3 3 6 0.060269153 0.045930620 1.433853e-02 4.030817e-03
## 104 3 3 6 0.110187622 0.065010563 4.517706e-02 1.472473e-02
## 105 3 3 6 0.049971342 0.078360257 -2.838891e-02 2.408679e-03
## 106 3 3 6 0.073863541 0.044646873 2.921667e-02 3.300730e-03
## 107 3 3 6 0.088332059 0.022819507 6.551255e-02 2.539892e-03
## 108 3 3 6 0.123054396 0.036262129 8.679227e-02 2.009747e-02
## 109 3 3 6 0.097778962 0.053851653 4.392731e-02 1.205601e-02
## 110 3 3 6 0.017975029 0.105957806 -8.798278e-02 1.080819e-04
## 111 3 3 6 0.060664665 0.029840417 3.082425e-02 6.704541e-04
## 112 3 3 6 0.034616282 0.128556437 -9.394015e-02 1.694271e-03
## 113 3 3 6 0.123814416 0.064670717 5.914370e-02 1.800581e-02
## 114 3 3 6 0.059222191 0.107113373 -4.789118e-02 3.552854e-03
## 115 3 3 6 0.008804432 0.016965570 -8.161138e-03 2.266135e-05
## 116 3 3 6 0.038216538 0.102595541 -6.437900e-02 1.622320e-03
## 117 3 3 6 0.037480182 0.052822079 -1.534190e-02 1.459874e-04
## 118 3 3 6 0.051395204 0.118871439 -6.747623e-02 8.396419e-04
## 119 3 3 6 0.052465782 0.139753541 -8.728776e-02 1.997023e-03
## 120 3 3 6 0.239907767 0.056077641 1.838301e-01 8.812370e-02
## 121 3 3 6 0.047311634 0.041869023 5.442610e-03 1.221958e-03
## 122 3 3 6 0.150575539 0.022988933 1.275866e-01 9.597966e-03
## 123 3 3 6 0.023379660 0.020591168 2.788493e-03 8.010647e-04
## 124 3 3 6 0.031990198 0.116827639 -8.483744e-02 4.138260e-04
## 125 3 3 6 0.027773226 0.154084923 -1.263117e-01 1.625854e-03
## 126 3 3 6 0.025118699 0.039950488 -1.483179e-02 1.517537e-03
## 127 3 3 6 0.038734138 0.072307302 -3.357316e-02 3.388728e-04
## 128 3 3 6 0.048627272 0.081102561 -3.247529e-02 4.406133e-04
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## 364 3 3 6 0.025572987 0.114664807 -8.909182e-02 7.718975e-04
## 365 3 3 6 0.102112706 0.038661229 6.345148e-02 7.545346e-03
## 366 3 3 6 0.036035134 0.059819933 -2.378480e-02 1.108739e-04
## 367 3 3 6 0.007698627 0.276525919 -2.688273e-01 6.941245e-05
## 368 3 3 6 0.055753699 0.032944284 2.280941e-02 2.248119e-03
## 369 3 3 6 0.011102857 0.006297684 4.805172e-03 4.719059e-05
## 370 3 3 6 0.037342125 0.096180651 -5.883853e-02 3.146125e-04
## 371 3 3 6 0.042338735 0.064259649 -2.192091e-02 1.344368e-03
## 372 3 3 6 0.193073792 0.064232729 1.288411e-01 1.107088e-02
## 373 3 3 6 0.032655468 0.024273163 8.382305e-03 5.979974e-04
## 374 3 3 6 0.089642804 0.013927450 7.571535e-02 2.101072e-02
## 375 3 3 6 0.054841845 0.054850529 -8.683850e-06 4.454399e-03
## 376 3 3 6 0.031222068 0.036359997 -5.137930e-03 8.166150e-04
## 377 3 3 6 0.109415162 0.016646867 9.276830e-02 9.765701e-03
## 378 3 3 6 0.033976568 0.023775570 1.020100e-02 1.511998e-03
## 379 3 3 6 0.074509028 0.077956983 -3.447954e-03 9.233745e-03
## 380 3 3 6 0.186592389 0.185543637 1.048752e-03 2.652918e-02
## 381 3 3 6 0.055105342 0.097792185 -4.268684e-02 3.072336e-03
## 382 3 3 6 0.099624140 0.103883117 -4.258977e-03 1.859809e-02
## 383 3 3 6 0.504824420 0.011990331 4.928341e-01 7.027093e-01
## 384 3 3 6 0.047919120 0.031334984 1.658414e-02 4.200392e-03
## 385 3 3 6 0.028577268 0.025457822 3.119446e-03 5.758001e-04
## 386 3 3 6 0.190091712 0.100430147 8.966156e-02 9.700478e-02
## 387 3 3 6 0.021561993 0.044198393 -2.263640e-02 4.037777e-04
## 388 3 3 6 0.075109541 0.051177410 2.393213e-02 3.047223e-03
## 389 3 3 6 0.033084139 0.109732621 -7.664848e-02 3.762968e-04
## 390 3 3 6 0.073712509 0.077729181 -4.016672e-03 9.475660e-03
## 391 3 3 6 0.054009114 0.108679859 -5.467075e-02 8.304857e-04
## 392 3 3 6 0.268882379 0.048314162 2.205682e-01 6.705204e-02
## 393 3 3 6 0.008972607 0.010952728 -1.980121e-03 1.336576e-06
## 394 3 3 6 0.036327682 0.011917497 2.441019e-02 2.138887e-03
## 395 3 3 6 0.039067006 0.041545193 -2.478187e-03 6.526194e-04
## 396 3 3 6 0.117809523 0.408856212 -2.910467e-01 1.021141e-02
## 397 3 3 6 0.037975789 0.046380263 -8.404474e-03 1.530839e-03
## 398 3 3 6 0.006662133 0.036045881 -2.938375e-02 6.187234e-06
## 399 3 3 6 0.065151366 0.023946110 4.120526e-02 7.304073e-03
## 400 3 3 6 0.044493377 0.187254435 -1.427611e-01 1.233866e-03
## 401 3 3 6 0.082862644 0.051098217 3.176443e-02 4.807976e-03
## 402 3 3 6 0.097624075 0.038556112 5.906796e-02 1.806404e-03
## 403 3 3 6 0.048603710 0.023595991 2.500772e-02 9.383150e-04
## 404 3 3 6 0.048342523 0.074213161 -2.587064e-02 3.222417e-04
## 405 3 3 6 0.015994779 0.021549856 -5.555076e-03 7.773389e-05
## 406 3 3 6 0.101806455 0.050733985 5.107247e-02 2.374671e-02
## 407 3 3 6 0.144786448 0.056513088 8.827336e-02 3.901414e-02
## 408 3 3 6 0.129914254 0.089809501 4.010475e-02 4.483260e-02
## 409 3 3 6 0.156245401 0.070480776 8.576463e-02 3.763995e-02
## 410 3 3 6 0.032234278 0.008059280 2.417500e-02 3.231023e-04
## 411 3 3 6 0.247584393 0.062927657 1.846567e-01 1.506462e-01
## 412 3 3 6 0.041232095 0.029831085 1.140101e-02 1.646441e-03
## 413 3 3 6 0.073416286 0.049170046 2.424624e-02 8.817540e-03
## 414 3 3 6 0.016366269 0.213644280 -1.972780e-01 2.393059e-04
## 415 3 3 6 0.178716750 0.019979388 1.587374e-01 6.053462e-02
## 416 3 3 6 0.431180007 0.066517722 3.646623e-01 3.470782e-01
## 417 3 3 6 0.058973175 0.123572334 -6.459916e-02 3.516041e-03
## 418 3 3 6 0.026680372 0.036031801 -9.351429e-03 1.907302e-04
## 419 3 3 6 0.013797677 0.011311994 2.485682e-03 1.606743e-05
## 420 3 3 6 0.040044051 0.063081408 -2.303736e-02 5.572082e-04
## 421 3 3 6 0.103989160 0.083643952 2.034521e-02 1.997058e-02
## 422 3 3 6 0.031863658 0.091867344 -6.000369e-02 1.009639e-03
## 423 3 3 6 0.036488971 0.008219066 2.826991e-02 4.783332e-04
## 424 3 3 6 0.018884075 0.025280032 -6.395957e-03 2.843125e-04
## 425 3 3 6 0.053850028 0.025039525 2.881050e-02 1.946035e-03
## 426 3 3 6 0.043169127 0.012694993 3.047413e-02 1.245935e-03
## 427 3 3 6 0.020880073 0.179255380 -1.583753e-01 3.235261e-04
## 428 3 3 6 0.038161816 0.018428689 1.973313e-02 1.115515e-03
## 429 3 3 6 0.067531968 0.810450664 -7.429187e-01 6.562919e-03
## 430 3 3 6 0.090995685 0.021739684 6.925600e-02 1.075379e-02
## 431 3 3 6 0.056946855 0.009800274 4.714658e-02 3.309741e-03
## 432 3 3 6 0.113394308 0.012131847 1.012625e-01 3.293995e-02
## 433 3 3 6 0.020722371 0.423560518 -4.028381e-01 1.354291e-05
## 434 3 3 6 0.053749109 0.045431634 8.317475e-03 2.760701e-03
## 435 3 3 6 0.521313779 0.042456058 4.788577e-01 7.260177e-01
## 436 3 3 6 0.050013476 0.030652251 1.936122e-02 4.458801e-03
## 437 3 3 6 0.248968482 0.245722131 3.246351e-03 1.699808e-01
## 438 3 3 6 0.020293959 0.060648983 -4.035502e-02 3.135473e-04
## 439 3 3 6 0.276733776 0.100515305 1.762185e-01 8.975825e-02
## 440 3 3 6 0.072984978 0.064254512 8.730466e-03 3.621146e-03
## 441 3 3 6 0.092990896 0.015644469 7.734643e-02 3.792765e-03
## 442 3 3 6 0.008571798 0.110013330 -1.014415e-01 3.195680e-05
## 443 3 3 6 0.044939491 0.055327456 -1.038796e-02 1.462479e-03
## 444 3 3 6 0.045023628 0.008489380 3.653425e-02 1.085007e-03
## 445 3 3 6 0.033731152 0.054730462 -2.099931e-02 9.939465e-04
## 446 3 3 6 0.070340667 0.159865132 -8.952447e-02 9.783203e-03
## 447 3 3 6 0.163564760 0.021336315 1.422284e-01 4.311574e-02
## 448 3 3 6 0.209712120 0.392979018 -1.832669e-01 9.687320e-02
## 449 3 3 6 0.174085433 0.048994305 1.250911e-01 7.388710e-02
## 450 3 3 6 0.113451884 0.121101650 -7.649766e-03 1.938278e-02
## 451 3 3 6 0.007608242 0.043153544 -3.554530e-02 5.519882e-05
## 452 3 3 6 0.008493857 0.018002922 -9.509065e-03 4.853288e-05
## 453 3 3 6 0.019142534 0.037155852 -1.801332e-02 1.080865e-04
## 454 3 3 6 0.019353084 0.036169669 -1.681659e-02 3.869953e-04
## 455 3 3 6 0.031422529 0.034743738 -3.321209e-03 1.235230e-03
## 456 3 3 6 0.394181363 0.158886113 2.352952e-01 4.110447e-01
## 457 3 3 6 0.009578296 0.042315951 -3.273765e-02 9.469382e-06
## 458 3 3 6 0.033219210 0.203981627 -1.707624e-01 6.522966e-04
## 459 3 3 6 0.016138935 0.058601502 -4.246257e-02 1.702014e-05
## 460 3 3 6 0.103601315 0.193538277 -8.993696e-02 1.578634e-02
## 461 3 3 6 0.051956280 0.027796715 2.415957e-02 3.521006e-03
## 462 3 3 6 0.039031995 0.062259393 -2.322740e-02 5.428453e-04
## 463 3 3 6 0.059879714 0.154723448 -9.484373e-02 5.812766e-03
## 464 3 3 6 0.037991109 0.043610545 -5.619436e-03 4.007633e-04
## 465 3 3 6 0.055306192 0.314008940 -2.587027e-01 4.078147e-03
## 466 3 3 6 0.025913575 0.008786951 1.712662e-02 4.451062e-04
## 467 3 3 6 0.020307844 0.049824675 -2.951683e-02 2.884099e-04
## 468 3 3 6 0.008045676 0.081818959 -7.377328e-02 3.166059e-05
## 469 3 3 6 0.021065950 0.024275022 -3.209072e-03 1.105497e-04
## 470 3 3 6 0.054626183 0.078587783 -2.396160e-02 2.962443e-03
## 471 3 3 6 0.078148883 0.022679603 5.546928e-02 8.294291e-03
## 472 3 3 6 0.102382596 0.066530516 3.585208e-02 1.097943e-02
## 473 3 3 6 0.106745062 0.029554588 7.719047e-02 8.079620e-03
## 474 3 3 6 0.038987521 0.028230682 1.075684e-02 2.647275e-05
## 475 3 3 6 0.248939096 0.192396109 5.654299e-02 3.965806e-02
## 476 3 3 6 0.136707896 0.071790104 6.491779e-02 4.181417e-02
## 477 3 3 6 0.009876623 0.023069796 -1.319317e-02 7.190231e-05
## 478 3 3 6 0.057948449 0.109001540 -5.105309e-02 3.640918e-04
## 479 3 3 6 0.168872394 0.112203867 5.666853e-02 6.683827e-02
## 480 3 3 6 0.028366088 0.031741485 -3.375397e-03 4.384337e-04
## 481 3 3 6 0.012668425 0.175987825 -1.633194e-01 1.668278e-04
## 482 3 3 6 0.028705593 0.079266197 -5.056060e-02 4.628680e-04
## 483 3 3 6 0.017309604 0.062582275 -4.527267e-02 1.412100e-04
## 484 3 3 6 0.081343028 0.022999788 5.834324e-02 1.309312e-02
## 485 3 3 6 0.064322089 0.279778665 -2.154566e-01 2.346105e-03
## 486 3 3 6 0.008145380 0.041436230 -3.329085e-02 3.354803e-05
## 487 3 3 6 0.030834824 0.104121391 -7.328657e-02 1.889745e-03
## 488 3 3 6 0.045913029 0.034624845 1.128818e-02 2.186380e-04
## 489 3 3 6 0.026259497 0.037356242 -1.109675e-02 1.719780e-03
## 490 3 3 6 0.082074588 0.171851231 -8.977664e-02 8.913014e-03
## 491 3 3 6 0.015568368 0.231071493 -2.155031e-01 2.534135e-04
## 492 3 3 6 0.065012965 0.043901675 2.111129e-02 7.867809e-03
## 493 3 3 6 0.058700384 0.019167304 3.953308e-02 2.627411e-03
## 494 3 3 6 0.045469361 0.014631047 3.083831e-02 5.179767e-03
## 495 3 3 6 0.129614836 0.067660557 6.195428e-02 1.162781e-03
## 496 3 3 6 0.074466142 0.031656768 4.280937e-02 9.459675e-03
## 497 3 3 6 0.012101626 0.027115861 -1.501424e-02 8.487583e-05
## 498 3 3 6 0.023099688 0.044620123 -2.152044e-02 2.141193e-04
## 499 3 3 6 0.009615031 0.121741348 -1.121263e-01 4.652268e-05
## 500 3 3 6 0.023280401 0.061057178 -3.777678e-02 3.538601e-04
## 501 3 3 6 0.083352404 0.067727813 1.562459e-02 6.282411e-04
## 502 3 3 6 0.060067530 0.159477467 -9.940994e-02 2.502830e-03
## 503 3 3 6 0.069174262 0.220172603 -1.509983e-01 3.537752e-03
## 504 3 3 6 0.028190377 0.062069626 -3.387925e-02 7.422893e-04
## 505 3 3 6 0.082366827 0.061239177 2.112765e-02 1.630481e-02
## 506 3 3 6 0.029710748 0.018315029 1.139572e-02 7.077969e-04
## 507 3 3 6 0.049725692 0.004597582 4.512811e-02 1.778311e-03
## 508 3 3 6 0.209377693 0.040282732 1.690950e-01 6.683049e-02
## 509 3 3 6 0.060901243 0.068364027 -7.462784e-03 6.139794e-03
## 510 3 3 6 0.015000091 0.223559577 -2.085595e-01 2.207363e-04
## 511 3 3 6 0.028018955 0.030090922 -2.071967e-03 5.967452e-04
## 512 3 3 6 0.114711110 0.056006266 5.870484e-02 2.891770e-02
## 513 3 3 6 0.012216693 0.088232334 -7.601564e-02 1.400949e-05
## 514 3 3 6 0.028441504 0.027655109 7.863945e-04 6.381079e-04
## 515 3 3 6 0.045017041 0.274739141 -2.297221e-01 7.442737e-04
## 516 3 3 6 0.050847880 0.023888946 2.695893e-02 9.730094e-04
## 517 3 3 6 0.035227761 0.014350187 2.087757e-02 2.825422e-04
## 518 3 3 6 0.035309725 0.018993782 1.631594e-02 1.101364e-03
## 519 3 3 6 0.057199461 0.026885624 3.031384e-02 3.212768e-03
## 520 3 3 6 0.035121300 0.073357121 -3.823582e-02 5.532425e-04
## 521 3 3 6 0.014407594 0.088637251 -7.422966e-02 2.013338e-04
## 522 3 3 6 0.029307038 0.028762829 5.442085e-04 6.686120e-04
## 523 3 3 6 0.075217357 0.051914761 2.330260e-02 3.532756e-05
## 524 3 3 6 0.034871845 0.051615288 -1.674344e-02 6.135946e-04
## 525 3 3 6 0.082553792 0.051037911 3.151588e-02 1.153329e-02
## 526 3 3 6 0.031222851 0.223119263 -1.918964e-01 4.198965e-04
## 527 3 3 6 0.005683210 0.060348780 -5.466557e-02 3.082336e-06
## 528 3 3 6 0.112714786 0.115679763 -2.964977e-03 1.212544e-02
## 529 3 3 6 0.026986276 0.130713170 -1.037269e-01 3.106083e-04
## 530 3 3 6 0.058459811 0.018972983 3.948683e-02 1.769569e-03
## 531 3 3 6 0.020936630 0.018038183 2.898447e-03 5.475598e-04
## 532 3 3 6 0.035714618 0.224840054 -1.891254e-01 3.728856e-04
## 533 3 3 6 0.102052312 0.027379646 7.467267e-02 7.901445e-03
## 534 3 3 6 0.166691893 0.167943375 -1.251482e-03 4.888863e-02
## 535 3 3 6 0.014126691 0.016376996 -2.250305e-03 1.119206e-04
## 536 3 3 6 0.011049398 0.049730624 -3.868123e-02 9.992038e-06
## 537 3 3 6 0.025140480 0.036006920 -1.086644e-02 4.152824e-04
## 538 3 3 6 0.033912305 0.015745610 1.816669e-02 3.947174e-04
## 539 3 3 6 0.033549726 0.034538042 -9.883161e-04 8.715168e-04
## 540 3 3 6 0.018990133 0.020130403 -1.140270e-03 2.692784e-04
## 541 3 3 6 0.270534267 0.031864924 2.386693e-01 1.818008e-01
## 542 3 3 6 0.028217984 0.014581915 1.363607e-02 5.954611e-04
## 543 3 3 6 0.128389783 0.029391379 9.899840e-02 3.210766e-02
## 544 3 3 6 0.066704976 0.039874832 2.683014e-02 5.510155e-03
## 545 3 3 6 0.056401405 0.037995375 1.840603e-02 4.398971e-03
## 546 3 3 6 0.026861815 0.009988139 1.687368e-02 1.274355e-03
## 547 3 3 6 0.064361491 0.064847948 -4.864574e-04 5.723532e-03
## 548 3 3 6 0.013512623 0.076014156 -6.250153e-02 3.295903e-06
## 549 3 3 6 0.107087446 0.014217246 9.287020e-02 2.971052e-02
## 550 3 3 6 0.203138853 0.157228720 4.591013e-02 6.892462e-02
## 551 3 3 6 0.022465242 0.015583253 6.881988e-03 1.991729e-04
## 552 3 3 6 0.066140237 0.012863702 5.327654e-02 2.296837e-03
## 553 3 3 6 0.055175435 0.071194222 -1.601879e-02 6.865151e-03
## 554 3 3 6 0.046372830 0.062467419 -1.609459e-02 3.008346e-03
## 555 3 3 6 0.006904810 0.085646287 -7.874148e-02 1.359453e-05
## 556 3 3 6 0.209302073 0.133426919 7.587515e-02 1.268055e-04
## 557 3 3 6 0.017641502 0.119020807 -1.013793e-01 1.985710e-04
## 558 3 3 6 0.104176019 0.157683572 -5.350755e-02 3.213605e-03
## 559 3 3 6 0.067053311 0.180201604 -1.131483e-01 5.864272e-03
## 560 3 3 6 0.034492410 0.079298609 -4.480620e-02 8.367025e-04
## 561 3 3 6 0.102333371 0.074122460 2.821091e-02 3.546546e-04
## 562 3 3 6 0.009192421 0.049149877 -3.995746e-02 1.193325e-05
## 563 3 3 6 0.063071948 0.024412582 3.865937e-02 3.183187e-03
## 564 3 3 6 0.009938745 0.174995088 -1.650563e-01 4.563696e-05
## 565 3 3 6 0.080663924 0.017189651 6.347427e-02 3.993721e-03
## 566 3 3 6 0.070053358 0.020066844 4.998651e-02 8.641561e-03
## 567 3 3 6 0.017063510 0.079053873 -6.199036e-02 8.542296e-05
## 568 3 3 6 0.014805869 0.016902033 -2.096164e-03 1.011904e-04
## 569 3 3 6 0.046443009 0.048074580 -1.631571e-03 1.187027e-05
## 570 3 3 6 0.023888675 0.123402485 -9.951381e-02 9.128983e-05
## 571 3 3 6 0.009995849 0.066507201 -5.651135e-02 3.547280e-05
## 572 3 3 6 0.105624277 0.113242353 -7.618076e-03 1.057979e-02
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## 574 3 3 6 0.041693948 0.023043205 1.865074e-02 1.391195e-03
## 575 3 3 6 0.146307308 0.019215747 1.270916e-01 2.342519e-02
## 576 3 3 6 0.007939636 0.072687303 -6.474767e-02 1.323241e-05
## 577 3 3 6 0.035752148 0.023973185 1.177896e-02 8.769830e-04
## 578 3 3 6 0.018385618 0.099143457 -8.075784e-02 1.879551e-04
## 579 3 3 6 0.092316408 0.012758358 7.955805e-02 1.428981e-02
## 580 3 3 6 0.043021494 0.037083545 5.937949e-03 6.646309e-04
## 581 3 3 6 0.053888924 0.059748241 -5.859316e-03 2.937054e-03
## 582 3 3 6 0.025207350 0.034077645 -8.870295e-03 1.512196e-04
## 583 3 3 6 0.139346313 0.260196786 -1.208505e-01 1.517518e-02
## 584 3 3 6 0.015781857 0.072066695 -5.628484e-02 1.037658e-05
## 585 3 3 6 0.081065617 0.216602639 -1.355370e-01 3.231990e-03
## 586 3 3 6 0.042665856 0.143190810 -1.005250e-01 4.246318e-04
## 587 3 3 6 0.092557751 0.052318544 4.023921e-02 5.232082e-03
## 588 3 3 6 0.150093411 0.009004812 1.410886e-01 1.515410e-02
## 589 3 3 6 0.023055607 0.011929171 1.112644e-02 7.151893e-04
## 590 3 3 6 0.067055375 0.057043955 1.001142e-02 8.894834e-03
## 591 3 3 6 0.711925359 0.041937411 6.699879e-01 4.590262e-01
## 592 3 3 6 0.065177328 0.146771702 -8.159437e-02 5.522154e-03
## 593 3 3 6 0.025798214 0.254325365 -2.285272e-01 1.294455e-03
## 594 3 3 6 0.075442114 0.051989544 2.345257e-02 7.450216e-03
## 595 3 3 6 0.014278705 0.014533843 -2.551377e-04 1.552053e-04
## 596 3 3 6 0.058690719 0.075313280 -1.662256e-02 5.211968e-03
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## 828 3 3 6 0.135217560 0.024952542 1.102650e-01 4.153078e-02
## 829 3 3 6 0.069152035 0.160747428 -9.159539e-02 4.309964e-03
## 830 3 3 6 0.072543641 0.054008334 1.853531e-02 1.405595e-02
## 831 3 3 6 0.251914583 0.033466679 2.184479e-01 1.621923e-01
## 832 3 3 6 0.059896434 0.077655892 -1.775946e-02 1.918148e-05
## 833 3 3 6 0.205517170 0.068397442 1.371197e-01 5.226198e-02
## 834 3 3 6 0.069094399 0.054720571 1.437383e-02 7.197847e-03
## 835 3 3 6 0.038870471 0.019724407 1.914606e-02 5.896849e-06
## 836 3 3 6 0.036200469 0.055515270 -1.931480e-02 1.330333e-03
## 837 3 3 6 0.270273251 0.027197084 2.430762e-01 6.076117e-02
## 838 3 3 6 0.037814402 0.113636141 -7.582174e-02 1.959583e-03
## 839 3 3 6 0.010807923 0.073899694 -6.309177e-02 1.827991e-04
## 840 3 3 6 0.067619856 0.082966966 -1.534711e-02 8.680959e-03
## 841 3 3 6 0.087983847 0.025862702 6.212114e-02 5.318548e-03
## 842 3 3 6 0.077246094 0.067047903 1.019819e-02 5.610038e-03
## 843 3 3 6 0.038556255 0.046274208 -7.717953e-03 3.035174e-04
## 844 3 3 6 0.033033379 0.032743605 2.897738e-04 7.492142e-04
## 845 3 3 6 0.013219912 0.091372477 -7.815256e-02 1.307020e-05
## 846 3 3 6 0.052041823 0.108004564 -5.596274e-02 3.201612e-03
## 847 3 3 6 0.048791645 0.008805747 3.998590e-02 8.302187e-04
## 848 3 3 6 0.059907863 0.027504667 3.240320e-02 4.863906e-03
## 849 3 3 6 0.031568913 0.087595849 -5.602694e-02 1.160422e-03
## 850 3 3 6 0.170223602 0.061319546 1.089041e-01 1.987772e-02
## 851 3 3 6 0.468095362 0.066781038 4.013143e-01 6.149326e-01
## 852 3 3 6 0.015014782 0.220802408 -2.057876e-01 2.309573e-04
## 853 3 3 6 0.013389766 0.012231185 1.158581e-03 2.588260e-04
## 854 3 3 6 0.072761177 0.005751720 6.700946e-02 4.304333e-03
## 855 3 3 6 0.004973986 0.085184123 -8.021014e-02 4.239050e-05
## 856 3 3 6 0.034559970 0.281645315 -2.470853e-01 1.011362e-03
## 857 3 3 6 0.091782373 0.045002782 4.677959e-02 1.193100e-02
## 858 3 3 6 0.025360355 0.055339727 -2.997937e-02 3.264598e-04
## 859 3 3 6 0.041781506 0.056068097 -1.428659e-02 8.387983e-04
## 860 3 3 6 0.149479306 0.037692822 1.117865e-01 6.096069e-02
## 861 3 3 6 0.015598586 0.012348732 3.249854e-03 1.728762e-04
## 862 3 3 6 0.033651811 0.030659325 2.992486e-03 4.616013e-04
## 863 3 3 6 0.179718644 0.114573219 6.514542e-02 6.384606e-03
## 864 3 3 6 0.049007674 0.187442483 -1.384348e-01 1.976920e-03
## 865 3 3 6 0.036747844 0.048351975 -1.160413e-02 3.058662e-05
## 866 3 3 6 0.020587515 0.167375678 -1.467882e-01 7.860917e-04
## 867 3 3 6 0.195480915 0.042121562 1.533594e-01 2.944960e-02
## 868 3 3 6 0.036392108 0.041252912 -4.860805e-03 1.377754e-03
## 869 3 3 6 0.022134434 0.020249381 1.885053e-03 1.014916e-03
## 870 3 3 6 0.046888413 0.025148991 2.173942e-02 5.485019e-03
## 871 3 3 6 0.048564277 0.013603575 3.496070e-02 5.955217e-03
## 872 3 3 6 0.036586596 0.089598228 -5.301163e-02 1.707537e-03
## 873 3 3 6 0.059855017 0.016568824 4.328619e-02 3.721300e-03
## 874 3 3 6 0.193610718 0.035905325 1.577054e-01 6.823648e-02
## 875 3 3 6 0.030192731 0.047659915 -1.746718e-02 1.250706e-03
## 876 3 3 6 0.006820076 0.053293137 -4.647306e-02 1.919530e-05
## 877 3 3 6 0.008247655 0.115245784 -1.069981e-01 4.211263e-05
## 878 3 3 6 0.188378322 0.072151591 1.162267e-01 9.643224e-02
## 879 3 3 6 0.027941839 0.021853308 6.088532e-03 6.132545e-04
## 880 3 3 6 0.138064263 0.040804360 9.725990e-02 3.894751e-02
## 881 3 3 6 0.059652394 0.175160961 -1.155086e-01 3.408189e-03
## 882 3 3 6 0.153053642 0.051180607 1.018730e-01 1.993585e-02
## 883 3 3 6 0.020497502 0.224289333 -2.037918e-01 1.962260e-04
## 884 3 3 6 0.039922655 0.322242335 -2.823197e-01 3.244133e-03
## 885 3 3 6 0.024796205 0.020545078 4.251127e-03 2.589115e-04
## 886 3 3 6 0.020089021 0.034262158 -1.417314e-02 1.732052e-04
## 887 3 3 6 0.053746699 0.042561143 1.118556e-02 3.471505e-03
## 888 3 3 6 0.134259239 0.167369664 -3.311042e-02 2.381725e-02
## 889 3 3 6 0.031080971 0.062068846 -3.098787e-02 1.939537e-03
## 890 3 3 6 0.065536481 0.053590580 1.194590e-02 1.963853e-03
## 891 3 3 6 0.121306753 0.072121949 4.918480e-02 7.856758e-03
## 892 3 3 6 0.014755876 0.100850053 -8.609418e-02 9.882716e-05
## 893 3 3 6 0.107379420 0.027270371 8.010905e-02 8.088475e-03
## 894 3 3 6 0.051416324 0.022883728 2.853260e-02 2.477648e-03
## 895 3 3 6 0.016334336 0.102762703 -8.642837e-02 2.157670e-05
## 896 3 3 6 0.069637158 0.008448078 6.118908e-02 2.650232e-03
## 897 3 3 6 0.023462077 0.395089354 -3.716273e-01 3.759419e-04
## 898 3 3 6 0.047076996 0.143904011 -9.682702e-02 4.464821e-05
## 899 3 3 6 0.024562547 0.039920870 -1.535832e-02 6.477566e-04
## 900 3 3 6 0.042439632 0.099711275 -5.727164e-02 2.015939e-03
## 901 3 3 6 0.126496784 0.137910442 -1.141366e-02 1.637939e-02
## 902 3 3 6 0.191301704 0.063175549 1.281262e-01 3.980688e-02
## 903 3 3 6 0.020802623 0.025562553 -4.759930e-03 2.496875e-04
## 904 3 3 6 0.008412499 0.015690309 -7.277810e-03 7.804485e-05
## 905 3 3 6 0.032312414 0.039109568 -6.797154e-03 6.349695e-04
## 906 3 3 6 0.478776991 0.206937544 2.718394e-01 5.388275e-01
## 907 3 3 6 0.009923277 0.030682746 -2.075947e-02 5.277936e-05
## 908 3 3 6 0.052775047 0.086455041 -3.367999e-02 3.814238e-03
## 909 3 3 6 0.092016337 0.043635543 4.838079e-02 4.245261e-03
## 910 3 3 6 0.073345714 0.078401629 -5.055915e-03 1.120223e-02
## 911 3 3 6 0.002769667 0.109267273 -1.064976e-01 9.418699e-06
## 912 3 3 6 0.103794357 0.041879608 6.191475e-02 6.182050e-03
## 913 3 3 6 0.030300029 0.012573081 1.772695e-02 6.254747e-04
## 914 3 3 6 0.130591265 0.046219560 8.437171e-02 3.133628e-02
## 915 3 3 6 0.170359691 0.031150267 1.392094e-01 6.699829e-02
## 916 3 3 6 0.028058965 0.036225942 -8.166977e-03 1.407798e-03
## 917 3 3 6 0.015345335 0.038943750 -2.359841e-02 1.306478e-04
## 918 3 3 6 0.185759246 0.143481470 4.227778e-02 3.922580e-02
## 919 3 3 6 0.084242180 0.081758581 2.483599e-03 5.941239e-03
## 920 3 3 6 0.007974314 0.004230099 3.744215e-03 2.965071e-05
## 921 3 3 6 0.323531780 0.088767630 2.347641e-01 2.625049e-01
## 922 3 3 6 0.050139352 0.034100604 1.603875e-02 2.444069e-03
## 923 3 3 6 0.127194922 0.016077244 1.111177e-01 2.647514e-02
## 924 3 3 6 0.020738243 0.021691788 -9.535451e-04 1.599243e-04
## 925 3 3 6 0.022188875 0.081241144 -5.905227e-02 4.529539e-04
## 926 3 3 6 0.023208136 0.041525132 -1.831700e-02 9.658827e-04
## 927 3 3 6 0.051983068 0.033683180 1.829989e-02 1.455945e-03
## 928 3 3 6 0.023450668 0.039707074 -1.625641e-02 4.849171e-05
## 929 3 3 6 0.139609683 0.068519656 7.109003e-02 5.258504e-02
## 930 3 3 6 0.078159919 0.192524827 -1.143649e-01 2.947129e-03
## 931 3 3 6 0.026207109 0.030771807 -4.564697e-03 3.633016e-04
## 932 3 3 6 0.163532518 0.018782657 1.447499e-01 2.190946e-02
## 933 3 3 6 0.064052878 0.023364699 4.068818e-02 5.591199e-03
## 934 3 3 6 0.096150481 0.018448131 7.770235e-02 9.766966e-03
## 935 3 3 6 0.028923421 0.292456127 -2.635327e-01 2.007435e-04
## 936 3 3 6 0.209398864 0.019667726 1.897311e-01 1.770954e-02
## 937 3 3 6 0.056580523 0.025295958 3.128457e-02 1.378231e-03
## 938 3 3 6 0.066905149 0.035336344 3.156881e-02 3.117786e-03
## 939 3 3 6 0.295519489 0.128913668 1.666058e-01 2.008649e-01
## 940 3 3 6 0.154708110 0.029260351 1.254478e-01 5.409179e-02
## 941 3 3 6 0.007779506 0.074470128 -6.669062e-02 7.005897e-06
## 942 3 3 6 0.062947963 0.034707832 2.824013e-02 1.794020e-03
## 943 3 3 6 0.111403747 0.124781109 -1.337736e-02 2.509337e-02
## 944 3 3 6 0.046543343 0.006218861 4.032448e-02 1.963591e-03
## 945 3 3 6 0.030093742 0.061982925 -3.188918e-02 4.129481e-04
## 946 3 3 6 0.016049040 0.023701191 -7.652151e-03 5.444847e-05
## 947 3 3 6 0.058086512 0.025437402 3.264911e-02 1.487896e-03
## 948 3 3 6 0.023112871 0.342589090 -3.194762e-01 7.805064e-04
## 949 3 3 6 0.036538460 0.022468652 1.406981e-02 8.976432e-04
## 950 3 3 6 0.061357833 0.170535277 -1.091774e-01 6.472040e-03
## 951 3 3 6 0.028298358 0.008764766 1.953359e-02 5.308157e-05
## 952 3 3 6 0.044926825 0.369703136 -3.247763e-01 3.679957e-03
## 953 3 3 6 0.046525643 0.022346006 2.417964e-02 4.213592e-04
## 954 3 3 6 0.025141206 0.096930095 -7.178889e-02 5.319149e-04
## 955 3 3 6 0.029497775 0.281383746 -2.518860e-01 1.027924e-03
## 956 3 3 6 0.109569858 0.056771417 5.279844e-02 1.973222e-02
## 957 3 3 6 0.042423734 0.035252188 7.171546e-03 6.827994e-04
## 958 3 3 6 0.042503034 0.038827654 3.675380e-03 1.540167e-03
## 959 3 3 6 0.091807622 0.017579773 7.422785e-02 1.019561e-02
## 960 3 3 6 0.005789142 0.038024486 -3.223534e-02 8.752693e-06
## 961 3 3 6 0.094236276 0.036364859 5.787142e-02 2.059478e-02
## 962 3 3 6 0.007605483 0.044176464 -3.657098e-02 1.052875e-04
## 963 3 3 6 0.033847002 0.032408888 1.438115e-03 4.542689e-04
## 964 3 3 6 0.011231876 0.015479830 -4.247954e-03 1.804129e-04
## 965 3 3 6 0.268350463 0.263688418 4.662045e-03 7.808009e-02
## 966 3 3 6 0.048901520 0.047265447 1.636073e-03 2.997470e-03
## 967 3 3 6 0.181894249 0.134481055 4.741319e-02 3.205636e-02
## 968 3 3 6 0.168056665 0.006480504 1.615762e-01 2.088107e-02
## 969 3 3 6 0.058526596 0.016625687 4.190091e-02 1.574511e-03
## 970 3 3 6 0.041634881 0.075188937 -3.355406e-02 3.684345e-04
## 971 3 3 6 0.012011560 0.057924106 -4.591255e-02 1.590458e-04
## 972 3 3 6 0.232186677 0.200473378 3.171330e-02 6.668307e-02
## 973 3 3 6 0.092389033 0.075062554 1.732648e-02 1.404606e-02
## 974 3 3 6 0.111655540 0.027557888 8.409765e-02 9.897522e-03
## 975 3 3 6 0.061008151 0.131995656 -7.098751e-02 9.112969e-03
## 976 3 3 6 0.052610434 0.141425140 -8.881471e-02 4.515668e-03
## 977 3 3 6 0.051278329 0.084494564 -3.321623e-02 1.116148e-03
## 978 3 3 6 0.075885394 0.270347440 -1.944620e-01 6.144948e-03
## 979 3 3 6 0.046454699 0.008554723 3.789998e-02 1.857622e-03
## 980 3 3 6 0.012647028 0.054743864 -4.209684e-02 1.050454e-04
## 981 3 3 6 0.105808774 0.062310534 4.349824e-02 2.582936e-02
## 982 3 3 6 0.046688969 0.117282844 -7.059387e-02 5.834052e-03
## 983 3 3 6 0.042248857 0.040662457 1.586399e-03 1.675160e-03
## 984 3 3 6 0.167763772 0.018187364 1.495764e-01 3.586016e-02
## 985 3 3 6 0.014306032 0.069636247 -5.533021e-02 2.160137e-04
## 986 3 3 6 0.079021628 0.892216424 -8.131948e-01 4.583040e-05
## 987 3 3 6 0.031480861 0.176822481 -1.453416e-01 9.978130e-07
## 988 3 3 6 0.007671333 0.207606321 -1.999350e-01 1.437053e-05
## 989 3 3 6 0.066140081 0.015059287 5.108079e-02 2.600425e-03
## 990 3 3 6 0.009600158 0.106981804 -9.738165e-02 1.112312e-04
## 991 3 3 6 0.059658051 0.227314894 -1.676568e-01 8.211457e-03
## 992 3 3 6 0.246084906 0.040359422 2.057255e-01 9.866069e-02
## 993 3 3 6 0.032231307 0.272490626 -2.402593e-01 4.544901e-04
## 994 3 3 6 0.053665788 0.191253139 -1.375874e-01 1.640437e-03
## 995 3 3 6 0.104674197 0.088796124 1.587807e-02 9.651295e-03
## 996 3 3 6 0.023638453 0.112268912 -8.863046e-02 2.197354e-04
## 997 3 3 6 0.028088531 0.259031607 -2.309431e-01 5.402697e-04
## 998 3 3 6 0.086825216 0.024755245 6.206997e-02 7.350544e-03
## 999 3 3 6 0.027013312 0.035448763 -8.435451e-03 7.786582e-04
## 1000 3 3 6 0.038976510 0.014081650 2.489486e-02 8.712388e-04
## var.y stderr df statistic pvalue conf.low
## 1 1.574596e-02 0.077558087 2.572026 -3.027166e+00 0.0687156292 -5.065480e-01
## 2 3.278089e-02 0.112287047 2.601274 -9.960909e-01 0.4026427927 -5.022729e-01
## 3 7.542315e-01 0.501680146 2.004335 -1.972498e+00 0.1870224784 -3.143651e+00
## 4 6.362665e-01 0.460660966 2.002258 -1.603214e+00 0.2499346145 -2.718462e+00
## 5 6.672930e+00 1.544676323 2.289285 -7.132874e-01 0.5413825148 -7.004645e+00
## 6 1.524742e-02 0.074159122 2.326071 -1.523808e+00 0.2498641657 -3.928317e-01
## 7 4.376739e-03 0.115651166 2.482489 5.071644e-02 0.9633469632 -4.096415e-01
## 8 7.624563e-03 0.069018050 3.982080 -2.021984e+00 0.1135577047 -3.315188e-01
## 9 4.699899e-01 0.396428734 2.012573 -1.567859e+00 0.2566885713 -2.317068e+00
## 10 2.545341e-02 0.092203301 2.008005 -1.845884e+00 0.2056888685 -5.654037e-01
## 11 8.390546e-02 0.169766526 2.121765 -9.675195e-01 0.4302952845 -8.559625e-01
## 12 7.005868e-02 0.152893195 2.004014 -1.177095e+00 0.3600638952 -8.365550e-01
## 13 4.864697e+00 1.274796623 2.008734 -1.831002e+00 0.2080290099 -7.796371e+00
## 14 3.304686e-01 0.331924018 2.000630 -1.441237e+00 0.2861965422 -1.906104e+00
## 15 2.292447e-01 0.276492446 2.001737 -1.860412e+00 0.2037898933 -1.703052e+00
## 16 3.371742e-03 0.034443492 2.221540 -2.393292e+00 0.1264898231 -2.173324e-01
## 17 1.296840e-01 0.212013755 2.159074 -2.402464e+00 0.1289524632 -1.360103e+00
## 18 2.123427e-01 0.290483911 2.741205 -1.153029e+00 0.3394627725 -1.310776e+00
## 19 9.175629e-03 0.058704200 2.498946 -1.434951e+00 0.2637500941 -2.941482e-01
## 20 3.550402e-01 0.344387521 2.008653 -2.832687e+00 0.1047942729 -2.451222e+00
## 21 1.782649e-01 0.245692541 2.063475 -9.419215e-01 0.4430265267 -1.257994e+00
## 22 2.852035e+00 0.975101357 2.000607 -1.471687e+00 0.2789181282 -5.629347e+00
## 23 6.928432e-02 0.156669483 2.250248 -1.188320e+00 0.3449536974 -7.932882e-01
## 24 4.712613e+00 1.253514843 2.001091 -1.465367e+00 0.2803814080 -7.227481e+00
## 25 4.555496e+00 1.236038883 2.024480 -1.204782e+00 0.3502402068 -6.746251e+00
## 26 5.333066e-05 0.080968741 2.010876 1.588608e+00 0.2524263555 -2.179534e-01
## 27 4.388249e-04 0.016787040 3.994193 2.962260e-01 0.7818210141 -4.166228e-02
## 28 1.482114e-03 0.023534339 2.477392 -7.400950e-01 0.5230599159 -1.020966e-01
## 29 3.126334e-04 0.043696346 2.230151 9.285753e-01 0.4423168319 -1.300125e-01
## 30 1.693943e-04 0.042967435 2.126071 9.566803e-01 0.4345115235 -1.336498e-01
## 31 3.808190e-05 0.050836843 2.019744 1.985733e+00 0.1842119476 -1.157486e-01
## 32 1.650882e-04 0.010795659 3.987644 2.715208e+00 0.0534276955 -6.977543e-04
## 33 4.577218e-05 0.041652145 2.035487 1.015441e+00 0.4151566302 -1.339583e-01
## 34 3.694784e-04 0.022569932 3.157749 1.338798e-01 0.9015787304 -6.681806e-02
## 35 4.639276e-05 0.030423935 2.067944 1.036585e+00 0.4057547603 -9.533024e-02
## 36 1.199938e-04 0.052563621 2.058744 1.108041e+00 0.3804398007 -1.618473e-01
## 37 3.386994e-04 0.011746736 2.846972 7.286910e-01 0.5215062399 -2.998649e-02
## 38 4.366713e-06 0.007477040 2.106852 1.306674e+00 0.3157210176 -2.088699e-02
## 39 3.888716e-06 0.011124741 2.042334 2.284546e+00 0.1471058939 -2.151258e-02
## 40 6.451554e-06 0.014476799 2.041466 2.046963e+00 0.1746642982 -3.145831e-02
## 41 3.754086e-06 0.035330292 2.004014 2.304606e+00 0.1474283632 -7.030015e-02
## 42 2.076863e-06 0.008241368 2.041186 2.268279e+00 0.1488631422 -1.608912e-02
## 43 1.730569e-06 0.069401781 2.000479 2.290683e+00 0.1490687817 -1.395657e-01
## 44 2.751824e-07 0.015560975 2.001516 2.003437e+00 0.1829400136 -3.572947e-02
## 45 2.218645e-05 0.004767605 3.565080 1.364913e+00 0.2520578952 -7.391472e-03
## 46 1.430017e-04 0.028591680 2.246735 3.431091e+00 0.0639067553 -1.283813e-02
## 47 7.255996e-06 0.060731556 2.002625 1.601408e+00 0.2502823750 -1.637229e-01
## 48 2.083404e-03 0.029035917 2.818516 2.781447e-01 0.8000453524 -8.778799e-02
## 49 8.768150e-06 0.023809147 2.020730 1.112919e+00 0.3805641913 -7.494432e-02
## 50 1.419805e-03 0.034459567 3.841851 6.635491e-01 0.5446718017 -7.438292e-02
## 51 3.436787e-01 0.338510124 2.001032 -1.154644e+00 0.3675106730 -1.846631e+00
## 52 7.776288e-01 0.509157152 2.000484 -9.555526e-01 0.4401205066 -2.676745e+00
## 53 8.982445e-04 0.018352902 2.492146 -1.242865e+00 0.3180499663 -8.856363e-02
## 54 1.623568e-02 0.085445777 3.244600 -5.082415e-01 0.6438421349 -3.041165e-01
## 55 5.839683e-04 0.016780566 3.489323 -7.291539e-01 0.5118081547 -6.164232e-02
## 56 3.088406e-03 0.032362636 2.069419 -2.381909e+00 0.1359215737 -2.119482e-01
## 57 1.784820e-03 0.066365187 2.609833 1.373625e+00 0.2756392596 -1.390791e-01
## 58 4.130908e-03 0.037749373 2.139400 -5.468950e-01 0.6361493386 -1.733355e-01
## 59 1.333100e-02 0.066735700 2.008990 -1.565434e+00 0.2574196900 -3.903830e-01
## 60 6.840082e-04 0.015164755 2.034507 -8.296485e-01 0.4927150288 -7.678097e-02
## 61 4.137420e-04 0.012352823 2.420953 -1.518983e+00 0.2467290921 -6.396962e-02
## 62 7.961992e-02 0.163673946 2.037553 -1.368665e+00 0.3024607613 -9.159540e-01
## 63 1.530313e-04 0.014958388 3.086449 -6.172625e-02 0.9545617132 -4.778210e-02
## 64 6.417041e-04 0.037530695 2.693950 9.562268e-02 0.9304809146 -1.239063e-01
## 65 1.498780e-04 0.032092628 2.203392 1.725426e+00 0.2149119711 -7.118661e-02
## 66 9.273275e-01 0.557086129 2.015991 -1.033960e+00 0.4090623263 -2.954825e+00
## 67 2.632799e-04 0.046975530 2.165384 1.233018e+00 0.3346053445 -1.301019e-01
## 68 6.826891e-03 0.047789317 2.014393 -1.168492e+00 0.3623123713 -2.600608e-01
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## 70 2.859621e-03 0.037342664 3.524922 -1.128512e+00 0.3300051690 -1.515719e-01
## 71 1.130585e-03 0.023811368 3.608547 -6.606731e-01 0.5485956213 -8.476921e-02
## 72 1.355624e-01 0.302445792 3.999423 1.424030e-01 0.8936474919 -7.967027e-01
## 73 2.276729e-03 0.049382843 3.500838 6.182427e-01 0.5743411617 -1.146432e-01
## 74 7.886948e-06 0.003827906 2.834684 1.682318e+01 0.0006302527 5.180352e-02
## 75 1.652863e-03 0.029228489 3.690030 2.394939e-02 0.9821313462 -8.321174e-02
## 76 3.543285e-04 0.081564839 2.072273 1.196815e+00 0.3503506019 -2.418550e-01
## 77 1.185589e-02 0.063660613 2.101870 -1.238437e+00 0.3359828836 -3.404127e-01
## 78 9.733315e-04 0.159687728 2.051540 1.391187e+00 0.2958304706 -4.486462e-01
## 79 1.130486e-04 0.011836047 3.296336 1.266544e+00 0.2874129391 -2.083165e-02
## 80 2.505585e-05 0.019741193 2.087559 2.942684e+00 0.0938105162 -2.352306e-02
## 81 4.392475e-04 0.050347001 2.244293 8.908038e-01 0.4580793475 -1.506774e-01
## 82 3.233766e-04 0.037148869 2.336488 8.313989e-01 0.4820908057 -1.087997e-01
## 83 3.265312e-04 0.013330592 3.807264 6.466269e-01 0.5547811445 -2.914251e-02
## 84 2.539041e-04 0.117840506 2.024528 1.036652e+00 0.4076710245 -3.790259e-01
## 85 4.133125e-02 0.117713065 2.023018 -1.046310e+00 0.4041659006 -6.241603e-01
## 86 8.102703e-04 0.212496194 2.024069 1.186037e+00 0.3561797013 -6.519288e-01
## 87 3.104421e-03 0.060035473 3.386117 6.456940e-02 0.9521437935 -1.754304e-01
## 88 2.595342e-04 0.011802677 3.778602 2.023446e-01 0.8500706387 -3.115257e-02
## 89 1.826469e-02 0.079427801 2.144709 -1.876858e+00 0.1927099908 -4.696517e-01
## 90 6.052224e-05 0.122047199 2.005425 1.227864e+00 0.3441083009 -3.739105e-01
## 91 2.080373e-02 0.083283909 2.000942 -1.187456e+00 0.3569126676 -4.570762e-01
## 92 5.081223e-05 0.317014012 2.000674 9.476557e-01 0.4433014427 -1.063141e+00
## 93 3.913183e-02 0.119205344 2.354718 -5.994416e-01 0.6015406248 -5.169863e-01
## 94 4.313901e-04 0.021505724 3.499521 -3.405311e-01 0.7528975155 -7.055613e-02
## 95 2.058187e-03 0.035269250 3.957957 1.753264e-01 0.8694265392 -9.215110e-02
## 96 9.668651e-07 0.016712659 2.004621 2.270191e+00 0.1509286389 -3.380922e-02
## 97 3.332630e-02 0.110428457 2.387228 -9.090143e-01 0.4455834512 -5.087914e-01
## 98 1.485669e-03 0.023758165 2.548444 -1.915639e+00 0.1673596006 -1.292953e-01
## 99 1.041059e-03 0.020553649 2.830261 -7.375929e-01 0.5171354475 -8.284735e-02
## 100 1.243004e-03 0.035172177 3.606874 9.861976e-01 0.3854822208 -6.731123e-02
## 101 5.614345e-05 0.019585520 2.204620 1.510395e+00 0.2587975468 -4.761902e-02
## 102 1.786101e-02 0.077195318 2.003659 -9.500167e-01 0.4422173494 -4.049008e-01
## 103 4.341480e-03 0.052827699 3.994500 2.714207e-01 0.7995170516 -1.324144e-01
## 104 8.143442e-03 0.087308210 3.694043 5.174434e-01 0.6342742918 -2.053565e-01
## 105 6.579608e-03 0.054736603 3.291277 -5.186459e-01 0.6368828370 -1.941805e-01
## 106 9.901712e-04 0.037819312 3.100873 7.725330e-01 0.4944007660 -8.895632e-02
## 107 3.401571e-04 0.030984129 2.526264 2.114391e+00 0.1416529707 -4.442550e-02
## 108 7.836821e-05 0.082007801 2.015597 1.058342e+00 0.4001076729 -2.634551e-01
## 109 9.643113e-04 0.065879483 2.317910 6.667829e-01 0.5651636780 -2.053475e-01
## 110 7.848977e-03 0.051500999 2.055070 -1.708370e+00 0.2263421119 -3.039795e-01
## 111 3.813458e-04 0.018724314 3.719015 1.646215e+00 0.1804182235 -2.274908e-02
## 112 3.272943e-02 0.107119406 2.206511 -8.769667e-01 0.4654349360 -5.158714e-01
## 113 4.298615e-03 0.086225338 2.903448 6.859202e-01 0.5435171402 -2.204991e-01
## 114 6.889644e-03 0.058998581 3.629417 -8.117345e-01 0.4668083371 -2.185093e-01
## 115 2.149901e-05 0.003836681 3.997231 -2.127135e+00 0.1005791548 -1.881638e-02
## 116 3.897341e-03 0.042893905 3.419150 -1.500889e+00 0.2194360788 -1.918910e-01
## 117 1.777359e-03 0.025320259 2.326347 -6.059139e-01 0.5984617132 -1.108749e-01
## 118 8.890254e-03 0.056949967 2.374441 -1.184834e+00 0.3410658394 -2.789652e-01
## 119 8.456038e-03 0.059028413 2.894757 -1.478741e+00 0.2389201204 -2.790660e-01
## 120 1.461337e-03 0.172805321 2.066313 1.063799e+00 0.3958015316 -5.372866e-01
## 121 9.024518e-04 0.026610834 3.911524 2.045261e-01 0.8481422186 -6.910469e-02
## 122 8.877027e-05 0.056823518 2.036992 2.245313e+00 0.1515472334 -1.126993e-01
## 123 1.552922e-04 0.017854568 2.747343 1.561781e-01 0.8866522908 -5.710639e-02
## 124 2.182483e-02 0.086098116 2.075818 -9.853577e-01 0.4250628974 -4.426190e-01
## 125 3.252315e-02 0.106691148 2.199464 -1.183900e+00 0.3485827144 -5.476920e-01
## 126 1.488509e-03 0.031654626 3.999627 -4.685504e-01 0.6637872252 -1.027224e-01
## 127 6.142759e-04 0.017824596 3.691786 -1.883530e+00 0.1386761024 -8.473500e-02
## 128 2.137911e-03 0.029317368 2.790792 -1.107715e+00 0.3542343942 -1.298606e-01
## 129 3.614587e-04 0.030682519 2.574692 5.262697e-01 0.6406095902 -9.128884e-02
## 130 5.292754e-04 0.099059521 2.073209 9.933211e-01 0.4220510087 -3.137180e-01
## 131 3.460218e-03 0.036089710 2.508450 -1.515565e+00 0.2438617740 -1.833941e-01
## 132 1.585550e-02 0.073480524 2.086407 -9.009204e-01 0.4593082720 -3.701394e-01
## 133 5.964210e-03 0.047008981 2.440726 -1.360970e+00 0.2855357676 -2.349747e-01
## 134 6.056358e-02 0.147604619 2.314900 -7.667193e-01 0.5137443198 -6.722513e-01
## 135 1.888961e-03 0.224366909 2.050657 2.035369e+00 0.1756158365 -4.862069e-01
## 136 2.693110e-03 0.039544123 3.914091 5.245653e-02 0.9607325963 -1.086747e-01
## 137 6.421422e-04 0.056469025 2.286341 1.632290e+00 0.2285255573 -1.238408e-01
## 138 9.003823e-04 0.042171951 2.779918 -4.782140e-01 0.6675637611 -1.605930e-01
## 139 6.222099e-04 0.015111575 2.400082 -3.205964e+00 0.0667578490 -1.041093e-01
## 140 2.322463e-04 0.113166511 2.024326 1.760108e+00 0.2189470781 -2.821665e-01
## 141 2.076473e-02 0.084845741 2.159952 -1.005087e+00 0.4139198170 -4.256180e-01
## 142 9.156839e-04 0.080752886 2.195948 8.856446e-01 0.4619709225 -2.478502e-01
## 143 1.504147e-03 0.167250049 2.072980 1.568152e+00 0.2530958158 -4.336044e-01
## 144 7.349397e-03 0.077868830 3.857845 3.894985e-01 0.7174483064 -1.890471e-01
## 145 1.308188e-02 0.103185473 3.873261 1.466770e-01 0.8907030014 -2.750891e-01
## 146 2.089751e-02 0.084396257 2.090046 -4.063243e-01 0.7223516158 -3.828323e-01
## 147 5.004560e-05 0.045131657 2.033028 2.276519e+00 0.1485038508 -8.845075e-02
## 148 1.956115e-03 0.025738316 2.063921 -1.424442e+00 0.2867387571 -1.441831e-01
## 149 1.061830e-03 0.040132387 3.043808 6.463642e-03 0.9952431483 -1.264261e-01
## 150 7.165641e-04 0.049574136 2.425680 9.954700e-01 0.4082165027 -1.318065e-01
## 151 1.853523e-03 0.026465219 2.525171 -1.908303e+00 0.1694265302 -1.444364e-01
## 152 5.971712e-04 0.045302710 2.424732 2.619888e-01 0.8139553762 -1.537266e-01
## 153 3.955772e-03 0.036325123 2.002803 -1.311039e+00 0.3199955204 -2.037086e-01
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## 156 1.697079e-03 0.024143823 2.121729 -2.489147e+00 0.1233917377 -1.584725e-01
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## 160 4.601019e-05 0.030600491 2.066587 1.183116e+00 0.3549979202 -9.147642e-02
## 161 1.736504e-04 0.013554949 3.518500 3.632155e-01 0.7371943631 -3.483202e-02
## 162 1.394804e-03 0.038089817 3.543152 -7.716731e-02 0.9426474442 -1.142945e-01
## 163 1.492827e-02 0.079398642 2.996565 1.749095e-01 0.8723011880 -2.389583e-01
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## 169 1.573043e-04 0.066660213 2.047757 9.753358e-01 0.4302000138 -2.154840e-01
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## 172 3.441193e-02 0.173035316 3.792701 -1.899471e-01 0.8590797883 -5.238258e-01
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## 174 9.069572e-07 0.070067606 2.000246 1.105519e+00 0.3841139315 -2.239799e-01
## 175 4.648597e-03 0.078969001 3.192201 6.089997e-01 0.5831451838 -1.948754e-01
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## 177 3.097033e-04 0.019259103 3.342919 9.802192e-01 0.3924784902 -3.900512e-02
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## 179 1.960582e-04 0.137433438 2.013888 9.717111e-01 0.4330873893 -4.538921e-01
## 180 5.100611e-03 0.048806517 3.381938 1.886090e-01 0.8611612272 -1.366517e-01
## 181 1.396847e-04 0.036374443 2.145706 8.673857e-01 0.4717672201 -1.151999e-01
## 182 6.654389e-04 0.030234504 3.162268 9.387548e-01 0.4138702598 -6.510313e-02
## 183 1.498482e-04 0.007444889 2.433392 3.649781e+00 0.0498788330 3.080998e-05
## 184 8.122560e-03 0.058208878 2.945924 -3.497973e-01 0.7500001781 -2.075466e-01
## 185 1.501952e-04 0.009884967 3.997553 -1.586023e-01 0.8816720477 -2.901947e-02
## 186 9.004516e-04 0.091865064 2.147311 6.789965e-01 0.5629486908 -3.080063e-01
## 187 1.262789e-02 0.072568695 2.944800 -3.299023e-01 0.7635443865 -2.573550e-01
## 188 2.222948e-02 0.087204612 2.105095 -2.194115e+00 0.1530947752 -5.491569e-01
## 189 7.353765e-02 0.157792705 2.062970 -9.487482e-01 0.4402554399 -8.091551e-01
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## 191 7.889913e-04 0.019408582 3.456946 4.733936e-01 0.6642496136 -4.820739e-02
## 192 2.846419e-03 0.034950220 3.061971 -9.690017e-01 0.4027066183 -1.438313e-01
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## 200 3.475423e-03 0.055367357 3.774896 -1.186773e-01 0.9115756541 -1.639789e-01
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## 202 2.370432e-03 0.039869843 3.999863 -2.072457e-01 0.8459414268 -1.189608e-01
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## 206 3.885875e-04 0.022051470 3.283200 5.758562e-01 0.6018356611 -5.417588e-02
## 207 3.075008e-04 0.038951790 2.288293 2.439912e-01 0.8274044130 -1.393988e-01
## 208 4.458653e-01 0.385962264 2.009288 -8.919823e-01 0.4661479794 -1.997598e+00
## 209 8.970067e-04 0.035241925 3.152448 9.777805e-02 0.9279966500 -1.057029e-01
## 210 8.342746e-05 0.007576517 3.996135 1.176926e+00 0.3045356186 -1.212681e-02
## 211 6.362368e-03 0.046062049 2.001741 -7.856631e-01 0.5143003480 -2.342132e-01
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## 214 1.740185e-04 0.058547847 2.068833 1.192677e+00 0.3518324883 -1.742185e-01
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## 217 7.123022e-03 0.238439292 2.174000 8.321500e-01 0.4867408693 -7.526987e-01
## 218 1.478520e-01 0.229926070 2.289195 -1.207326e+00 0.3371997234 -1.156266e+00
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## 220 1.200659e-04 0.092805655 2.018673 1.662919e+00 0.2370816655 -2.414634e-01
## 221 4.160126e-03 0.039263964 2.441446 -4.497044e-01 0.6897695542 -1.604502e-01
## 222 7.893987e-05 0.044339045 2.054254 9.371362e-01 0.4453668485 -1.444758e-01
## 223 1.839111e-04 0.233255491 2.004512 9.646887e-01 0.4362866230 -7.764367e-01
## 224 1.037622e-05 0.213758513 2.000303 1.113401e+00 0.3813966950 -6.815963e-01
## 225 9.530773e-03 0.058221426 2.266748 -4.729563e-01 0.6779282723 -2.518093e-01
## 226 9.220095e-04 0.018086182 2.256292 -2.247660e+00 0.1390590995 -1.105840e-01
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## 228 1.058397e-03 0.028503743 3.931973 5.454294e-01 0.6149213449 -6.413521e-02
## 229 6.241171e-04 0.014945163 2.292950 -1.222981e+00 0.3320883201 -7.531611e-02
## 230 2.789302e-03 0.042911544 3.999612 9.412347e-01 0.3998819249 -7.875627e-02
## 231 1.571602e-04 0.038910295 2.143182 1.263541e+00 0.3264319187 -1.079782e-01
## 232 8.471303e-03 0.058166865 2.762765 -5.372248e-01 0.6313383719 -2.256871e-01
## 233 1.136635e-03 0.022782243 3.301554 -4.023617e-01 0.7120707855 -7.806387e-02
## 234 2.642428e-03 0.140391812 2.186709 7.875790e-01 0.5072807658 -4.466572e-01
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## 238 9.983633e-04 0.025117388 3.987941 -4.262090e-01 0.6919533399 -8.052555e-02
## 239 6.722892e-03 0.047385834 2.007949 -9.045489e-01 0.4608528548 -2.459761e-01
## 240 2.220234e-01 0.274052384 2.059273 -8.902333e-01 0.4649358294 -1.391188e+00
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## 249 1.453720e-01 0.221113693 2.035816 -9.678932e-01 0.4336651608 -1.149529e+00
## 250 2.053356e-03 0.079234452 2.482229 6.588777e-01 0.5658833518 -2.324860e-01
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## 253 1.380892e-02 0.088412917 3.877549 8.995810e-02 0.9327746210 -2.406078e-01
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## 258 6.416379e-05 0.010355125 2.938379 1.344412e+00 0.2731810478 -1.942752e-02
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## 260 1.865693e-04 0.071270569 2.049573 1.050638e+00 0.4013649082 -2.247739e-01
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## 271 3.593210e-03 0.035731077 2.262600 -3.392364e+00 0.0646938079 -2.590568e-01
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## 276 9.635675e-05 0.010211186 3.486164 -1.346883e-01 0.9002681549 -3.145267e-02
## 277 6.723322e-06 0.016528031 2.033085 2.453675e+00 0.1315774151 -2.946241e-02
## 278 9.591889e-03 0.057124965 2.082491 -1.179836e+00 0.3552823763 -3.040887e-01
## 279 7.141626e-03 0.049534957 2.122831 -1.254032e+00 0.3302531834 -2.638577e-01
## 280 3.371019e-03 0.033735350 2.051255 -1.298386e+00 0.3209422565 -1.855322e-01
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## 282 6.755973e-03 0.048677069 2.208078 -4.177020e+00 0.0443905092 -3.949440e-01
## 283 1.309807e-03 0.312357870 2.017980 9.263432e-01 0.4513120896 -1.043207e+00
## 284 4.170835e-03 0.281728350 2.071291 1.005399e+00 0.4174466432 -8.898132e-01
## 285 3.583767e-03 0.080630983 2.857000 7.043229e-02 0.9484873575 -2.583459e-01
## 286 4.363990e-04 0.013005989 2.634577 1.383702e+00 0.2720241115 -2.683965e-02
## 287 2.406195e-03 0.030881783 2.730057 -4.023427e-01 0.7168350179 -1.164376e-01
## 288 5.690941e-03 0.074460758 3.637438 1.164343e-01 0.9134491263 -2.064524e-01
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## 290 3.743992e-04 0.018112398 3.783584 7.741935e-01 0.4843396582 -3.742055e-02
## 291 3.611854e-03 0.107795083 2.456259 4.464964e-01 0.6915913533 -3.421542e-01
## 292 5.506505e-03 0.043558833 2.134677 -1.020503e+00 0.4089974826 -2.209831e-01
## 293 3.815071e-04 0.015882767 3.999729 -3.481370e+00 0.0253232251 -9.939259e-02
## 294 4.660227e-02 0.125982214 2.086847 -7.284469e-01 0.5393306122 -6.127752e-01
## 295 2.526540e-02 0.092185628 2.036280 -9.386902e-01 0.4454626882 -4.764808e-01
## 296 3.038437e-02 0.100661257 2.001803 -9.708682e-01 0.4339479781 -5.304657e-01
## 297 1.253369e-02 0.064913634 2.034352 -1.193050e+00 0.3534304077 -3.522748e-01
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## 299 1.852317e-03 0.027876034 2.969374 -2.592358e-01 0.8123848192 -9.646034e-02
## 300 4.232364e-03 0.038070881 2.109372 -1.282876e+00 0.3224122992 -2.047701e-01
## 301 4.661808e-04 0.026761078 3.029398 1.422387e+00 0.2492268674 -4.663544e-02
## 302 2.343053e-04 0.015454357 3.572371 2.827185e+00 0.0541338512 -1.319433e-03
## 303 3.597906e-05 0.043150441 2.025930 2.072129e+00 0.1723983636 -9.398938e-02
## 304 1.823023e-04 0.035254048 2.205087 6.455621e-01 0.5792903697 -1.161786e-01
## 305 4.983345e-02 0.130175376 2.080510 -9.408246e-01 0.4427935993 -6.623055e-01
## 306 6.223305e-04 0.014846307 2.249106 -2.859054e-01 0.7991685539 -6.179999e-02
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## 308 2.630991e-05 0.008505475 2.541499 6.970302e-01 0.5441075781 -2.412330e-02
## 309 4.019656e-03 0.052211694 3.998847 2.219714e-01 0.8352114732 -1.333899e-01
## 310 5.215771e-04 0.113382639 2.054827 8.838852e-01 0.4678510099 -3.753649e-01
## 311 9.079561e-02 0.174112762 2.006615 -1.047397e+00 0.4045252053 -9.291503e-01
## 312 3.702571e-03 0.040923618 3.266457 -1.058541e+00 0.3617265348 -1.677479e-01
## 313 1.334507e-02 0.119993958 3.490375 -2.305778e-01 0.8305131394 -3.809142e-01
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## 315 1.370682e-02 0.072375621 2.573637 -4.250596e-01 0.7037763677 -2.842617e-01
## 316 2.361631e-06 0.003907162 2.216840 1.908491e+00 0.1839587310 -7.872858e-03
## 317 5.472218e-03 0.048978211 3.146605 -9.320011e-01 0.4171661326 -1.974893e-01
## 318 7.180538e-03 0.118445339 2.789408 7.769947e-01 0.4976828664 -3.015368e-01
## 319 8.538493e-02 0.168715959 2.000482 -1.069106e+00 0.3969323225 -9.061339e-01
## 320 1.191778e-03 0.037271164 3.380586 3.669571e-01 0.7354386783 -9.772865e-02
## 321 1.170744e-03 0.049178523 2.742141 9.505264e-01 0.4178896722 -1.184270e-01
## 322 8.981260e-04 0.173831182 2.040022 1.749624e+00 0.2198242258 -4.299091e-01
## 323 8.232926e-01 0.527040972 2.048695 -8.807536e-01 0.4694455503 -2.680991e+00
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## 332 1.998722e-01 0.261772705 2.114032 -1.157089e+00 0.3612333073 -1.372948e+00
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## 405 5.156175e-04 0.014063562 2.589634 -3.949978e-01 0.7230838823 -5.460411e-02
## 406 2.046454e-03 0.092723902 2.342172 5.508016e-01 0.6298401950 -2.969228e-01
## 407 6.895924e-04 0.115041636 2.070680 7.673166e-01 0.5207145958 -3.908673e-01
## 408 7.206139e-03 0.131705148 2.626745 3.045041e-01 0.7832413646 -4.148339e-01
## 409 3.678857e-03 0.117358147 2.387253 7.307940e-01 0.5299501568 -3.482711e-01
## 410 5.339477e-05 0.011202635 2.643454 2.157974e+00 0.1318697145 -1.435775e-02
## 411 3.675809e-03 0.226805350 2.097543 8.141639e-01 0.4976113842 -7.489840e-01
## 412 4.146175e-04 0.026211057 2.947236 4.349695e-01 0.6934622045 -7.286551e-02
## 413 4.317496e-03 0.066169066 3.579823 3.664286e-01 0.7346586251 -1.682933e-01
## 414 9.175233e-02 0.175111047 2.010433 -1.126588e+00 0.3764024369 -9.469857e-01
## 415 2.702529e-04 0.142366744 2.017857 1.114989e+00 0.3799926836 -4.486517e-01
## 416 7.566258e-04 0.340506901 2.008720 1.070939e+00 0.3958830035 -1.094343e+00
## 417 9.917620e-03 0.066917016 3.259762 -9.653622e-01 0.4003916624 -2.682731e-01
## 418 3.699940e-04 0.013671433 3.629078 -6.840123e-01 0.5351280134 -4.888953e-02
## 419 7.542334e-05 0.005522402 2.815128 4.501089e-01 0.6850159007 -1.576038e-02
## 420 2.207877e-03 0.030359431 2.949045 -7.588204e-01 0.5040043264 -1.206059e-01
## 421 1.568838e-02 0.109024401 3.943136 1.866115e-01 0.8611720314 -2.840844e-01
## 422 1.609305e-02 0.075504289 2.249966 -7.947057e-01 0.5019642392 -3.526227e-01
## 423 1.776741e-05 0.012859505 2.148373 2.198367e+00 0.1501592115 -2.355480e-02
## 424 2.436409e-04 0.013265913 3.976402 -4.821347e-01 0.6550462287 -4.331440e-02
## 425 2.160111e-04 0.026845523 2.438599 1.073196e+00 0.3777748623 -6.890400e-02
## 426 4.365017e-05 0.020733108 2.139964 1.469829e+00 0.2716039768 -5.336876e-02
## 427 2.357455e-02 0.089252597 2.054884 -1.774462e+00 0.2146129399 -5.327347e-01
## 428 2.857549e-05 0.019528531 2.102398 1.010477e+00 0.4141780181 -6.048890e-02
## 429 1.796351e+00 0.775223328 2.014614 -9.583286e-01 0.4383971918 -4.055356e+00
## 430 7.594468e-05 0.060082527 2.028247 1.152681e+00 0.3667950557 -1.858386e-01
## 431 1.693100e-04 0.034054127 2.204086 1.384460e+00 0.2897080308 -8.711312e-02
## 432 6.911799e-05 0.104895289 2.008393 9.653671e-01 0.4358478163 -3.482629e-01
## 433 4.878631e-01 0.403268576 2.000111 -9.989326e-01 0.4230557801 -2.137870e+00
## 434 3.460438e-03 0.045538038 3.950028 1.826490e-01 0.8640639095 -1.187497e-01
## 435 5.651095e-04 0.492132371 2.003113 9.730263e-01 0.4330362091 -1.635466e+00
## 436 1.762125e-05 0.038628236 2.015808 5.012195e-01 0.6656007850 -1.455999e-01
## 437 1.318999e-01 0.317217454 3.937346 1.023384e-02 0.9923322032 -8.830453e-01
## 438 6.078240e-03 0.046158378 2.205793 -8.742730e-01 0.4666525352 -2.222175e-01
## 439 1.362777e-02 0.185639454 2.593626 9.492512e-01 0.4223122238 -4.705497e-01
## 440 8.474818e-03 0.063497937 3.445268 1.374921e-01 0.8982931578 -1.793477e-01
## 441 4.553250e-04 0.037630174 2.473381 2.055436e+00 0.1512228751 -5.820988e-02
## 442 2.560974e-03 0.029399153 2.049906 -3.450492e+00 0.0721324870 -2.250301e-01
## 443 4.483357e-03 0.044519047 3.179319 -2.333375e-01 0.8297234812 -1.476523e-01
## 444 3.747668e-05 0.019343247 2.137997 1.888734e+00 0.1912629968 -4.175130e-02
## 445 1.398599e-03 0.028240312 3.888761 -7.435934e-01 0.4995338167 -1.002995e-01
## 446 5.833380e-02 0.150683996 2.652490 -5.941206e-01 0.5992462812 -6.066460e-01
## 447 1.044409e-03 0.121326212 2.096837 1.172281e+00 0.3570464747 -3.573605e-01
## 448 3.463523e-01 0.384371985 3.037611 -4.767957e-01 0.6657113935 -1.397986e+00
## 449 1.646551e-03 0.158675404 2.089095 7.883461e-01 0.5100275794 -5.304772e-01
## 450 1.956841e-02 0.113946165 3.999909 -6.713491e-02 0.9496961071 -3.240179e-01
## 451 1.150055e-03 0.020043730 2.191546 -1.773388e+00 0.2070476706 -1.149511e-01
## 452 1.381128e-04 0.007887663 3.251111 -1.205562e+00 0.3083423324 -3.354914e-02
## 453 4.927476e-04 0.014151961 2.837138 -1.272850e+00 0.2973643373 -6.454967e-02
## 454 1.218562e-03 0.023134083 3.153948 -7.269182e-01 0.5175011751 -8.844774e-02
## 455 7.985917e-04 0.026037290 3.823759 -1.275559e-01 0.9049251860 -7.694554e-02
## 456 2.408659e-02 0.380846108 2.233592 6.178224e-01 0.5938208492 -1.249604e+00
## 457 3.569401e-03 0.034539208 2.010612 -9.478403e-01 0.4428025686 -1.805988e-01
## 458 1.194782e-01 0.200108692 2.021838 -8.533483e-01 0.4825217253 -1.022910e+00
## 459 3.079299e-03 0.032126414 2.022108 -1.321734e+00 0.3159660895 -1.792532e-01
## 460 6.138868e-02 0.160390168 2.964814 -5.607386e-01 0.6145576086 -6.038142e-01
## 461 6.000428e-04 0.037063230 2.662433 6.518473e-01 0.5663430261 -1.027209e-01
## 462 1.011007e-02 0.059590017 2.214157 -3.897867e-01 0.7310339250 -2.572645e-01
## 463 2.368731e-03 0.052222273 3.397887 -1.816155e+00 0.1560909287 -2.505533e-01
## 464 3.927488e-03 0.037983553 2.403956 -1.479439e-01 0.8938910090 -1.453584e-01
## 465 3.704568e-02 0.117080923 2.435065 -2.209606e+00 0.1346676389 -6.853207e-01
## 466 3.819863e-05 0.012692581 2.340767 1.349341e+00 0.2928904023 -3.053126e-02
## 467 3.153229e-04 0.014186059 3.992067 -2.080693e+00 0.1060781270 -6.893453e-02
## 468 7.529194e-03 0.050202440 2.016820 -1.469516e+00 0.2784814643 -2.880598e-01
## 469 2.015341e-04 0.010199408 3.686654 -3.146331e-01 0.7700325619 -3.250213e-02
## 470 6.919301e-03 0.057392637 3.447275 -4.175030e-01 0.7009760846 -1.939091e-01
## 471 3.934280e-04 0.053813624 2.189308 1.030766e+00 0.4028822430 -1.579055e-01
## 472 8.257260e-03 0.080076404 3.921473 4.477234e-01 0.6779698989 -1.882425e-01
## 473 5.953550e-04 0.053774140 2.293152 1.435457e+00 0.2724409977 -1.280249e-01
## 474 1.996795e-03 0.025969647 2.053021 4.142082e-01 0.7179992742 -9.826120e-02
## 475 3.323465e-02 0.155876783 3.969178 3.627416e-01 0.7352881053 -3.775690e-01
## 476 7.692570e-03 0.128461073 2.711791 5.053499e-01 0.6514908070 -3.696167e-01
## 477 7.172403e-04 0.016218740 2.397004 -8.134524e-01 0.4888615054 -7.299134e-02
## 478 8.506585e-03 0.054377314 2.170892 -9.388675e-01 0.4401352592 -2.682270e-01
## 479 1.232319e-02 0.162441225 2.713247 3.488556e-01 0.7524876780 -4.926179e-01
## 480 2.093740e-03 0.029052676 2.802423 -1.161820e-01 0.9153277868 -9.963331e-02
## 481 4.250081e-02 0.119258311 2.015701 -1.369459e+00 0.3034657054 -6.726353e-01
## 482 3.549029e-03 0.036569098 2.512959 -1.382605e+00 0.2768295457 -1.808015e-01
## 483 7.523169e-03 0.050544959 2.075054 -8.956911e-01 0.4619826348 -2.553833e-01
## 484 2.647247e-04 0.066727922 2.080841 8.743452e-01 0.4710304422 -2.183353e-01
## 485 1.451243e-01 0.221713326 2.064648 -9.717800e-01 0.4309049078 -1.141352e+00
## 486 1.102404e-03 0.019458948 2.121614 -1.710825e+00 0.2220415776 -1.125809e-01
## 487 1.297350e-02 0.070387613 2.570542 -1.041186e+00 0.3856690035 -3.200260e-01
## 488 6.082009e-04 0.016601595 3.273376 6.799458e-01 0.5415385855 -3.913494e-02
## 489 3.022986e-03 0.039760810 3.719191 -2.790875e-01 0.7950014680 -1.248566e-01
## 490 6.315184e-02 0.154989087 2.553519 -5.792449e-01 0.6095058232 -6.355889e-01
## 491 3.802565e-02 0.112958788 2.026656 -1.907803e+00 0.1949757797 -6.954508e-01
## 492 8.813428e-04 0.054003556 2.442522 3.909241e-01 0.7273845632 -1.752221e-01
## 493 7.859641e-05 0.030033355 2.119549 1.316306e+00 0.3123683525 -8.295069e-02
## 494 4.093450e-04 0.043162917 2.314149 7.144632e-01 0.5401477194 -1.326913e-01
## 495 4.726609e-03 0.044307220 2.927875 1.398289e+00 0.2585636150 -8.103662e-02
## 496 3.168760e-04 0.057086341 2.133840 7.499057e-01 0.5272278279 -1.886247e-01
## 497 2.393030e-04 0.010395173 3.260189 -1.444347e+00 0.2374026243 -4.665171e-02
## 498 1.326079e-03 0.022658319 2.629461 -9.497807e-01 0.4211161328 -9.973305e-02
## 499 8.210598e-03 0.052463068 2.022664 -2.137243e+00 0.1646148325 -3.354501e-01
## 500 2.666335e-03 0.031729033 2.521668 -1.190606e+00 0.3337585655 -1.505029e-01
## 501 1.095584e-02 0.062139838 2.228620 2.514424e-01 0.8227876757 -2.271039e-01
## 502 4.163339e-03 0.047138693 3.766307 -2.108882e+00 0.1069086018 -2.335537e-01
## 503 4.304505e-02 0.124609791 2.326543 -1.211769e+00 0.3342461614 -6.211182e-01
## 504 4.025357e-03 0.039864964 2.713356 -8.498502e-01 0.4637971424 -1.686770e-01
## 505 6.558451e-03 0.087298846 3.384889 2.420152e-01 0.8227047193 -2.396522e-01
## 506 2.667159e-04 0.018023251 3.319882 6.322788e-01 0.5680885628 -4.295906e-02
## 507 9.120425e-06 0.024409231 2.020514 1.848813e+00 0.2044416991 -5.888108e-02
## 508 7.981304e-06 0.149263154 2.000478 1.132865e+00 0.3747785164 -4.729856e-01
## 509 5.774824e-03 0.063020150 3.996250 -1.184190e-01 0.9114493531 -1.824995e-01
## 510 1.415300e-01 0.217371228 2.006239 -9.594622e-01 0.4383019761 -1.141051e+00
## 511 1.475467e-04 0.015751104 2.932031 -1.315443e-01 0.9038502298 -5.286285e-02
## 512 5.484708e-04 0.099106290 2.075839 5.923423e-01 0.6117380509 -3.531284e-01
## 513 1.053887e-02 0.059309582 2.005317 -1.281676e+00 0.3281782760 -3.305568e-01
## 514 4.509560e-06 0.014635772 2.028267 5.373099e-02 0.9619734437 -6.135267e-02
## 515 1.820127e-01 0.246817762 2.016356 -9.307357e-01 0.4495619586 -1.283481e+00
## 516 2.808742e-04 0.020444100 3.065847 1.318666e+00 0.2771338661 -3.731988e-02
## 517 1.957354e-05 0.010035200 2.275783 2.080434e+00 0.1573247714 -1.765426e-02
## 518 3.274348e-04 0.021823525 3.092624 7.476310e-01 0.5074588418 -5.197420e-02
## 519 5.709481e-04 0.035513923 2.689086 8.535761e-01 0.4626053516 -9.047189e-02
## 520 9.843825e-03 0.058870104 2.224100 -6.494947e-01 0.5767002861 -2.685811e-01
## 521 1.401486e-02 0.068838455 2.057451 -1.078317e+00 0.3909705090 -3.626315e-01
## 522 6.771690e-04 0.021180030 3.999838 2.569442e-02 0.9807318849 -5.826192e-02
## 523 1.540736e-03 0.022920616 2.091668 1.016665e+00 0.4122566316 -7.128871e-02
## 524 3.184616e-03 0.035581881 2.743112 -4.705609e-01 0.6728135209 -1.362230e-01
## 525 2.736990e-03 0.068969257 2.898640 4.569555e-01 0.6797635993 -1.923816e-01
## 526 7.737299e-02 0.161030934 2.021707 -1.191674e+00 0.3545079799 -8.776763e-01
## 527 6.510459e-03 0.046595928 2.001894 -1.173183e+00 0.3614312946 -2.549700e-01
## 528 2.449977e-02 0.110491632 3.590175 -2.683440e-02 0.9800159114 -3.240557e-01
## 529 3.898366e-03 0.037456527 2.316696 -2.769261e+00 0.0930405327 -2.455136e-01
## 530 6.203660e-05 0.024709008 2.140058 1.598074e+00 0.2430632465 -6.043045e-02
## 531 4.551269e-04 0.018281929 3.966294 1.585416e-01 0.8817744196 -4.803090e-02
## 532 7.173093e-02 0.155030983 2.020793 -1.219920e+00 0.3457356450 -8.496356e-01
## 533 3.882654e-04 0.052566498 2.196081 1.420537e+00 0.2808226969 -1.332113e-01
## 534 1.027316e-02 0.140430039 2.804990 -8.911785e-03 0.9934849932 -4.662644e-01
## 535 3.726197e-04 0.012708793 3.102024 -1.770668e-01 0.8703898187 -4.195314e-02
## 536 4.054323e-04 0.011767531 2.098522 -3.287115e+00 0.0762954528 -8.710176e-02
## 537 2.279530e-03 0.029971169 2.705307 -3.625631e-01 0.7433770637 -1.124040e-01
## 538 1.559020e-04 0.013547685 3.366679 1.340945e+00 0.2632416300 -2.240955e-02
## 539 2.709942e-03 0.034551695 3.165822 -2.860398e-02 0.9788889833 -1.077597e-01
## 540 6.040354e-05 0.010483032 2.854280 -1.087729e-01 0.9205746824 -3.548651e-02
## 541 2.825725e-05 0.246190352 2.000622 9.694504e-01 0.4345618690 -8.202869e-01
## 542 1.924826e-04 0.016206415 3.170675 8.413995e-01 0.4588567578 -3.640439e-02
## 543 1.105169e-03 0.105218542 2.137520 9.408836e-01 0.4405505312 -3.269232e-01
## 544 8.995105e-04 0.046222885 2.636034 5.804515e-01 0.6074601575 -1.324570e-01
## 545 1.209431e-03 0.043237336 3.022453 4.256976e-01 0.6988239199 -1.186180e-01
## 546 2.985473e-06 0.020634445 2.009371 8.177431e-01 0.4990813460 -7.151358e-02
## 547 9.187064e-03 0.070499635 3.795221 -6.900140e-03 0.9948418566 -2.004612e-01
## 548 8.204513e-03 0.052306177 2.001607 -1.194917e+00 0.3545174870 -2.873838e-01
## 549 2.109990e-04 0.099869117 2.028406 9.299191e-01 0.4494012099 -3.311165e-01
## 550 5.631741e-02 0.204321672 3.959875 2.246954e-01 0.8333338982 -5.236520e-01
## 551 2.139683e-04 0.011735149 3.994877 5.864423e-01 0.5891148848 -2.571650e-02
## 552 2.939361e-05 0.027846186 2.051181 1.913244e+00 0.1926582113 -6.371616e-02
## 553 5.411010e-04 0.049686525 2.313328 -3.223970e-01 0.7740034950 -2.043170e-01
## 554 2.507646e-03 0.042879645 3.967311 -3.753433e-01 0.7266094336 -1.355354e-01
## 555 1.078933e-02 0.060008116 2.005040 -1.312180e+00 0.3195537439 -3.363146e-01
## 556 3.968913e-02 0.115204067 2.012780 6.586152e-01 0.5774504091 -4.168041e-01
## 557 1.623494e-02 0.074012422 2.048917 -1.369761e+00 0.3015498750 -4.126531e-01
## 558 2.817561e-02 0.102289150 2.450366 -5.231010e-01 0.6444375292 -4.245098e-01
## 559 2.093967e-02 0.094523270 3.038752 -1.197042e+00 0.3162681991 -4.118049e-01
## 560 8.766985e-03 0.056579407 2.378306 -7.919171e-01 0.4997147934 -2.546580e-01
## 561 4.340324e-03 0.039559991 2.324678 7.131172e-01 0.5405807212 -1.211326e-01
## 562 1.866843e-03 0.025025161 2.025568 -1.596691e+00 0.2498700037 -1.463400e-01
## 563 5.127729e-04 0.035099668 2.628054 1.101417e+00 0.3612668253 -8.254212e-02
## 564 1.717322e-02 0.075760273 2.010630 -2.178666e+00 0.1605465175 -4.893806e-01
## 565 1.886656e-04 0.037338037 2.188541 1.699990e+00 0.2203839768 -8.461781e-02
## 566 2.062315e-04 0.054307127 2.095406 9.204411e-01 0.4506859176 -1.737733e-01
## 567 3.582795e-03 0.034967691 2.095316 -1.772790e+00 0.2125164878 -2.060721e-01
## 568 1.042591e-04 0.008275456 3.999108 -2.532990e-01 0.8125257157 -2.507453e-02
## 569 1.249477e-03 0.020504853 2.037997 -7.956998e-02 0.9437044339 -8.829912e-02
## 570 2.711440e-02 0.095229005 2.013467 -1.044995e+00 0.4050904603 -5.066361e-01
## 571 3.466132e-03 0.034164331 2.040932 -1.654104e+00 0.2374470431 -2.007193e-01
## 572 1.343963e-02 0.089478884 3.944088 -8.513825e-02 0.9362976829 -2.574464e-01
## 573 7.679253e-02 0.160297461 2.015277 -5.388591e-01 0.6435808943 -7.710958e-01
## 574 2.430976e-04 0.023340183 2.678251 7.990830e-01 0.4889903159 -6.094058e-02
## 575 6.367005e-04 0.089557978 2.108640 1.419098e+00 0.2856594758 -2.398317e-01
## 576 8.099192e-03 0.052001360 2.006535 -1.245115e+00 0.3388416977 -2.877946e-01
## 577 9.035563e-04 0.024362124 3.999109 4.834949e-01 0.6540245339 -5.586708e-02
## 578 1.321253e-03 0.022429209 2.557734 -3.600566e+00 0.0474797043 -1.596544e-01
## 579 6.558712e-08 0.069016601 2.000018 1.152738e+00 0.3681891920 -2.173938e-01
## 580 3.451079e-03 0.037039212 2.742796 1.603152e-01 0.8837009140 -1.184442e-01
## 581 7.363342e-03 0.058595780 3.376498 -9.999553e-02 0.9259954614 -1.811085e-01
## 582 2.421365e-03 0.029283583 2.248838 -3.029102e-01 0.7877191996 -1.224064e-01
## 583 1.627862e-01 0.243557938 2.369673 -4.961878e-01 0.6620331644 -1.026719e+00
## 584 1.203773e-02 0.063372207 2.003448 -8.881628e-01 0.4680208503 -3.285042e-01
## 585 1.167447e-01 0.199980542 2.110652 -6.777510e-01 0.5646055808 -9.541691e-01
## 586 1.900495e-02 0.080476877 2.089328 -1.249116e+00 0.3333772411 -4.329819e-01
## 587 8.686184e-04 0.045095088 2.646259 8.923191e-01 0.4458454690 -1.147611e-01
## 588 3.619411e-05 0.071157785 2.009554 1.982757e+00 0.1852642775 -1.636880e-01
## 589 2.198414e-04 0.017654373 3.123408 6.302368e-01 0.5716416573 -4.382247e-02
## 590 1.926986e-03 0.060060579 2.827717 1.666887e-01 0.8788142895 -1.878882e-01
## 591 1.243311e-03 0.391692686 2.010834 1.710494e+00 0.2286314883 -1.006658e+00
## 592 2.227569e-02 0.096259788 2.934192 -8.476475e-01 0.4601737752 -3.918598e-01
## 593 4.780462e-02 0.127931071 2.108233 -1.786330e+00 0.2094561241 -7.527574e-01
## 594 2.906547e-03 0.058755887 3.354379 3.991527e-01 0.7138558224 -1.528412e-01
## 595 3.387418e-05 0.007938922 2.833321 -3.213757e-02 0.9764908526 -2.638233e-02
## 596 1.391564e-02 0.079849038 3.313853 -2.081748e-01 0.8472413546 -2.576505e-01
## 597 5.219002e-02 0.132246127 2.021236 -7.613215e-01 0.5252604928 -6.640002e-01
## 598 2.929568e-04 0.131827051 2.022603 1.046700e+00 0.4040411826 -4.231914e-01
## 599 5.541718e-05 0.241644801 2.001266 1.351068e+00 0.3091489875 -7.126053e-01
## 600 5.587360e-05 0.005179782 3.475845 -9.033560e-01 0.4245291807 -1.995760e-02
## 601 1.710395e-02 0.077250350 2.186427 -1.028293e+00 0.4039373994 -3.860827e-01
## 602 5.596532e-03 0.050902082 3.351254 -1.053764e-01 0.9220738932 -1.581627e-01
## 603 3.885155e-03 0.050635643 3.999584 -1.110479e-04 0.9999167146 -1.405985e-01
## 604 9.140399e-04 0.068101230 2.279875 1.176587e+00 0.3475510178 -1.809799e-01
## 605 1.428373e-01 0.243835148 2.936991 -4.469986e-01 0.6857777102 -8.944899e-01
## 606 8.357785e-04 0.021763734 3.879367 -3.360127e-01 0.7542455238 -6.848701e-02
## 607 1.168189e-02 0.065979567 2.465371 -9.382512e-01 0.4306470017 -3.001468e-01
## 608 5.021807e-01 0.418263472 2.180065 -6.498489e-01 0.5775942180 -1.936249e+00
## 609 2.212520e-02 0.086652630 2.072444 -8.496778e-01 0.4822804552 -4.342482e-01
## 610 2.102660e-03 0.036586525 3.991103 2.159780e-01 0.8395940352 -9.376796e-02
## 611 1.150216e-03 0.281358833 2.019467 8.643098e-01 0.4777624105 -9.562938e-01
## 612 1.133680e-02 0.076051083 3.656013 -2.173703e-01 0.8395040328 -2.357536e-01
## 613 4.565705e-02 0.124728083 2.088813 -1.383443e+00 0.2958221514 -6.879319e-01
## 614 4.151964e-03 0.042478253 3.112429 -3.674879e-01 0.7368296034 -1.480740e-01
## 615 9.682319e-03 0.060556030 2.534896 -1.622853e+00 0.2193653892 -3.126232e-01
## 616 7.759975e-03 0.310457940 2.110224 1.188327e+00 0.3512268963 -9.021824e-01
## 617 1.380784e-03 0.026096553 3.559775 9.788813e-02 0.9272801960 -7.357545e-02
## 618 1.899039e-03 0.351454662 2.020604 1.010129e+00 0.4178428487 -1.142492e+00
## 619 3.521971e-04 0.049593899 2.199995 6.985368e-01 0.5513401414 -1.611897e-01
## 620 6.098662e-03 0.054563177 3.528238 -1.232994e+00 0.2933588088 -2.271007e-01
## 621 4.212531e-04 0.058521463 2.170703 1.009253e+00 0.4118767415 -1.746795e-01
## 622 7.801092e-04 0.017153222 2.517086 -1.486381e+00 0.2503797176 -8.651631e-02
## 623 3.736468e-03 0.035389192 2.022177 -3.142668e+00 0.0868503425 -2.618948e-01
## 624 2.032650e-05 0.069613057 2.005600 1.038266e+00 0.4079406771 -2.264439e-01
## 625 3.514972e-06 0.023460631 2.008533 1.918837e+00 0.1944708001 -5.551598e-02
## 626 3.008228e-03 0.032864203 2.306584 -1.120912e+00 0.3653841381 -1.616728e-01
## 627 1.620259e-04 0.008785291 3.449404 -1.859164e+00 0.1478564266 -4.234015e-02
## 628 2.312999e-01 0.279954956 2.066119 -8.238428e-01 0.4942320690 -1.398992e+00
## 629 1.570173e-03 0.060881188 2.640393 1.910523e-01 0.8622109004 -1.979380e-01
## 630 1.290700e-03 0.026001512 3.723069 -1.573665e+00 0.1958939228 -1.152773e-01
## 631 4.643439e-03 0.201520237 2.158247 1.064325e+00 0.3916260723 -5.944257e-01
## 632 7.793692e-03 0.119387230 2.849370 8.371019e-01 0.4669191239 -2.916236e-01
## 633 1.083719e-01 0.198804385 2.373092 -8.528834e-01 0.4710950554 -9.081565e-01
## 634 1.892527e-03 0.028668906 3.109691 -3.133465e-01 0.7738652867 -9.842665e-02
## 635 1.115023e-05 0.054445248 2.005022 1.521283e-01 0.8930151026 -2.254150e-01
## 636 2.440788e-03 0.133215235 2.191752 7.169342e-01 0.5420998688 -4.322003e-01
## 637 7.028541e-06 0.009331108 2.110523 8.732659e-01 0.4704174074 -3.005099e-02
## 638 1.488013e-04 0.016404752 2.859913 5.616667e-01 0.6153362998 -4.447018e-02
## 639 2.035269e-03 0.044906246 3.613277 1.724623e-01 0.8722958613 -1.223783e-01
## 640 1.507441e-05 0.011600783 2.154909 1.283556e+00 0.3199817686 -3.173825e-02
## 641 1.295773e-02 0.072874260 2.872186 6.913935e-01 0.5410396657 -1.874829e-01
## 642 1.826597e-04 0.018312542 2.845736 1.303927e+00 0.2877078871 -3.622912e-02
## 643 2.006050e-01 0.259875032 2.039877 -1.382811e+00 0.2986364103 -1.456822e+00
## 644 5.661831e-04 0.040828793 2.502484 6.235966e-01 0.5850364593 -1.203845e-01
## 645 1.822414e-01 0.246831769 2.011774 -9.259409e-01 0.4517360378 -1.284649e+00
## 646 4.176805e-01 0.373846923 2.015361 -9.282109e-01 0.4506468565 -1.943850e+00
## 647 1.722802e-04 0.142709451 2.011311 1.275579e+00 0.3296148956 -4.286949e-01
## 648 2.111066e-04 0.040808247 2.176137 1.894598e+00 0.1882482798 -8.532856e-02
## 649 7.713842e-05 0.007458723 3.977257 -2.004546e+00 0.1159183408 -3.570687e-02
## 650 1.540340e-04 0.016130134 2.927384 -1.102088e+00 0.3527000856 -6.983805e-02
## 651 1.937875e-02 0.219466537 2.605021 1.206041e+00 0.3258491582 -4.976595e-01
## 652 1.152972e-03 0.036593414 3.385627 1.052771e+00 0.3617057639 -7.077609e-02
## 653 4.240194e-04 0.012126896 2.161666 -2.283183e+00 0.1403555259 -7.629899e-02
## 654 2.357527e-04 0.068256745 2.068606 8.474675e-01 0.4834120755 -2.267004e-01
## 655 2.494294e-04 0.033367340 2.320723 1.343955e-01 0.9038604322 -1.216501e-01
## 656 1.719320e-03 0.088741655 2.312024 6.249762e-01 0.5881119329 -2.809951e-01
## 657 4.202954e-04 0.034738237 2.516469 8.509901e-01 0.4680443263 -9.403579e-02
## 658 1.828667e-04 0.009929897 3.788316 1.745080e-01 0.8703918357 -2.645529e-02
## 659 9.509057e-03 0.056344951 2.006396 -1.568079e+00 0.2570129370 -3.300470e-01
## 660 6.431149e-03 0.174413579 2.301519 7.208384e-01 0.5371865732 -5.379476e-01
## 661 3.000760e-03 0.031640989 2.003595 -2.187816e+00 0.1599512347 -2.051311e-01
## 662 1.102549e-02 0.061876403 2.166804 -1.506026e+00 0.2617378344 -3.407130e-01
## 663 1.139304e-04 0.007511255 3.571799 -8.153277e-01 0.4657407544 -2.800271e-02
## 664 3.996710e-05 0.108485363 2.004533 1.173137e+00 0.3613112158 -3.384966e-01
## 665 3.994592e-05 0.159579890 2.002093 2.118826e+00 0.1681180075 -3.478076e-01
## 666 9.949518e-04 0.022034987 3.527227 -2.124367e-01 0.8434666346 -6.923369e-02
## 667 8.001831e-05 0.006366731 3.636782 4.130101e-01 0.7027738427 -1.576587e-02
## 668 3.507161e-06 0.009543060 2.052006 6.449879e-01 0.5835749098 -3.392402e-02
## 669 2.543418e-03 0.029365963 2.068645 -4.638640e+00 0.0407441058 -2.586356e-01
## 670 6.230158e-03 0.144879952 2.433972 5.788415e-01 0.6118243461 -4.442247e-01
## 671 8.440339e-03 0.054672716 2.248773 -1.126680e+00 0.3656796693 -2.735766e-01
## 672 2.909393e-04 0.043580179 2.214620 9.979500e-01 0.4145953263 -1.276383e-01
## 673 1.232408e-04 0.029007494 2.204771 1.460077e+00 0.2706292493 -7.198003e-02
## 674 3.797537e-07 0.016418774 2.001879 4.969869e+00 0.0381101580 1.101838e-02
## 675 7.895139e-04 0.028338193 3.575481 4.538919e-01 0.6760732295 -6.964168e-02
## 676 2.551471e-04 0.141889347 2.016969 8.800385e-01 0.4709890858 -4.807368e-01
## 677 1.755918e-04 0.036890219 2.179406 1.530685e+00 0.2554966926 -9.037198e-02
## 678 3.743354e-03 0.052772207 3.957285 2.089889e-01 0.8447731663 -1.361162e-01
## 679 2.111635e+00 0.839231051 2.002446 -1.084241e+00 0.3914466781 -4.516626e+00
## 680 5.814028e-04 0.026435642 3.337919 -1.004991e+00 0.3820926019 -1.060787e-01
## 681 1.757368e-04 0.019067779 2.740915 1.841917e-01 0.8666348171 -6.054769e-02
## 682 1.244780e-03 0.033558595 3.740994 -4.142355e-01 0.7013411797 -1.096748e-01
## 683 2.854031e-03 0.031551917 2.185358 -1.394966e-01 0.9008665225 -1.296996e-01
## 684 3.715939e-03 0.054593247 3.889169 6.867768e-01 0.5309777084 -1.158006e-01
## 685 1.382139e-03 0.041791635 3.270143 1.296227e+00 0.2787960565 -7.282360e-02
## 686 1.234076e-04 0.184328068 2.004849 1.064286e+00 0.3984597360 -5.950866e-01
## 687 1.190911e-03 0.029284617 3.978088 -7.894137e-01 0.4742585151 -1.046017e-01
## 688 1.643850e-02 0.339051514 2.199707 9.169243e-01 0.4483247018 -1.028086e+00
## 689 1.996355e-03 0.113692273 2.216467 1.569939e+00 0.2449875250 -2.676414e-01
## 690 1.841456e-06 0.159163749 2.000097 7.885286e-01 0.5130071002 -5.592894e-01
## 691 3.044511e-02 0.101111052 2.029589 -1.778875e+00 0.2153911486 -6.088878e-01
## 692 2.269058e-04 0.134434461 2.016810 8.508619e-01 0.4838200425 -4.594440e-01
## 693 4.174460e-06 0.058875575 2.001606 1.381734e+00 0.3010630735 -1.717761e-01
## 694 9.067598e-04 0.031007733 3.515418 2.780553e-01 0.7965419978 -8.235778e-02
## 695 3.392056e-04 0.060881096 2.125737 1.694575e+00 0.2248253132 -1.444807e-01
## 696 3.194312e-02 0.103303248 2.008962 -1.117732e+00 0.3794881229 -5.580486e-01
## 697 2.025080e-03 0.312798290 2.027787 1.015742e+00 0.4153845219 -1.010620e+00
## 698 4.653010e-05 0.010729647 2.608057 1.624934e+00 0.2160332330 -1.980642e-02
## 699 1.624184e-03 0.025252931 2.689781 -2.331730e-01 0.8322244984 -9.176113e-02
## 700 9.178788e-04 0.072730645 2.244642 1.322761e+00 0.3045518660 -1.862140e-01
## 701 3.137472e-03 0.136113454 2.238451 9.509067e-01 0.4326985164 -4.003144e-01
## 702 2.260583e-04 0.063471906 2.076215 1.558613e+00 0.2549586463 -1.647840e-01
## 703 1.542376e-02 0.764709058 2.035476 1.057506e+00 0.3994921252 -2.427245e+00
## 704 1.260711e-04 0.010353083 3.821891 -4.365830e+00 0.0132741813 -7.448065e-02
## 705 1.673573e-02 0.091839836 3.622551 -5.186430e-02 0.9613686098 -2.705792e-01
## 706 4.968951e-03 0.063452735 3.878170 1.191241e-01 0.9110914098 -1.708185e-01
## 707 2.693548e-04 0.013422537 3.999956 -5.797665e-01 0.5931601578 -4.504904e-02
## 708 4.523616e-03 0.047401485 3.580742 -3.493295e-01 0.7464024553 -1.544721e-01
## 709 2.075889e-03 0.043194113 3.749926 -4.016075e-02 0.9700112012 -1.248817e-01
## 710 5.290120e-04 0.023538755 3.533186 -3.336512e-01 0.7574875340 -7.675817e-02
## 711 1.775957e-03 0.050307188 3.117176 6.772084e-01 0.5451380156 -1.226801e-01
## 712 1.169362e-04 0.069595339 2.032450 1.098834e+00 0.3848839844 -2.184357e-01
## 713 1.727434e-04 0.041700568 2.136827 1.324402e+00 0.3092423249 -1.136225e-01
## 714 6.595730e-04 0.016598647 2.951622 3.916971e-01 0.7218450411 -4.681586e-02
## 715 3.382780e-03 0.035151793 2.379825 -4.098674e+00 0.0403808940 -2.743894e-01
## 716 2.269808e-02 0.088685061 2.157835 -1.444108e+00 0.2768907036 -4.841144e-01
## 717 1.119429e-02 0.063682786 2.344792 -8.482518e-01 0.4740444329 -2.928144e-01
## 718 1.047482e-03 0.042265357 2.917620 8.592289e-01 0.4550117408 -1.003659e-01
## 719 5.240552e-04 0.013927864 2.436615 -2.531372e+00 0.1046857513 -8.598287e-02
## 720 6.945656e-03 0.050672461 2.431082 -1.826676e+00 0.1863248191 -2.774260e-01
## 721 7.435498e-04 0.038987527 2.750796 4.343633e-01 0.6958145819 -1.137488e-01
## 722 1.487528e-03 0.099847275 2.208785 5.081733e-01 0.6575823427 -3.422066e-01
## 723 3.716646e-03 0.053229115 3.937979 -1.534276e-01 0.8856013290 -1.568770e-01
## 724 1.254310e-02 0.091962436 3.999495 4.152519e-02 0.9688675267 -2.515226e-01
## 725 6.114941e-03 0.062840439 3.995821 4.952189e-02 0.9628799066 -1.714330e-01
## 726 1.675607e-02 0.226010200 2.483780 5.761647e-01 0.6124888497 -6.814766e-01
## 727 5.143778e-03 0.085275708 3.126844 7.383958e-01 0.5117975887 -2.022951e-01
## 728 5.855070e-04 0.045481323 2.412246 8.205505e-01 0.4850779752 -1.295710e-01
## 729 3.432589e-04 0.030163864 2.563715 2.651858e+00 0.0907415880 -2.594183e-02
## 730 7.513392e-04 0.029941398 3.348063 8.065359e-01 0.4732894793 -6.577197e-02
## 731 1.575331e-02 0.072465805 2.000144 -1.387319e+00 0.2997055049 -4.123069e-01
## 732 1.228470e-03 0.097271092 2.180577 6.074533e-01 0.6008020895 -3.279161e-01
## 733 2.958380e-04 0.135156896 2.021710 8.651822e-01 0.4772920167 -4.586544e-01
## 734 1.381555e-02 0.068163128 2.035633 -1.632060e+00 0.2421001167 -3.996633e-01
## 735 8.134767e-03 0.066131147 3.782050 -3.417333e-01 0.7506885328 -2.104579e-01
## 736 1.411146e-03 0.023375850 2.630223 -3.760271e-01 0.7351387088 -8.946370e-02
## 737 5.084844e-03 0.041270638 2.019628 -9.432568e-01 0.4442865936 -2.148584e-01
## 738 2.364708e-03 0.030638064 2.736663 -2.340951e-01 0.8313142943 -1.102050e-01
## 739 8.382314e-04 0.017457667 2.360079 -3.622246e-01 0.7471040546 -7.145707e-02
## 740 9.510537e-04 0.019973055 2.968777 -3.030409e-02 0.9777464513 -6.454830e-02
## 741 9.425574e-01 0.560669244 2.002091 -1.062347e+00 0.3992906940 -3.005578e+00
## 742 1.586813e-02 0.075524407 2.311589 -6.864252e-01 0.5548520793 -3.382290e-01
## 743 2.198983e-03 0.030261590 2.939003 -1.823653e+00 0.1676208832 -1.526332e-01
## 744 1.576014e-02 0.072525601 2.005011 -1.383853e+00 0.3003211936 -4.116710e-01
## 745 5.682132e-03 0.237405611 2.138928 7.660754e-01 0.5191443032 -7.785853e-01
## 746 3.415771e-03 0.172800660 2.158321 1.112519e+00 0.3744009874 -5.013628e-01
## 747 7.133550e-03 0.078983058 3.786143 2.504556e-01 0.8152337459 -2.044828e-01
## 748 1.005766e-04 0.037442024 2.097942 2.045561e+00 0.1714575280 -7.751319e-02
## 749 4.115691e-03 0.037063451 2.005256 -1.159989e+00 0.3655443364 -2.020645e-01
## 750 3.150380e-04 0.012194693 3.418806 9.253518e-01 0.4153530560 -2.496890e-02
## 751 1.357917e-02 0.077563704 3.187825 -1.513974e-01 0.8887409909 -2.505581e-01
## 752 1.320321e-04 0.026953524 2.256877 9.792951e-01 0.4204626206 -7.780156e-02
## 753 2.432599e-04 0.014036732 3.878610 2.358310e-01 0.8254906816 -3.614770e-02
## 754 2.319664e-04 0.053690473 2.110166 1.676370e-01 0.8815690576 -2.108298e-01
## 755 1.158849e-04 0.008297466 3.941210 5.999828e-01 0.5813064239 -1.819528e-02
## 756 5.484231e-03 0.043616980 2.162446 -8.148476e-01 0.4951379457 -2.103267e-01
## 757 3.833000e-05 0.031231577 2.053081 1.002440e+00 0.4193694823 -9.979580e-02
## 758 3.446206e-02 0.107621210 2.033068 -8.740543e-01 0.4729653575 -5.499804e-01
## 759 2.736826e-04 0.144902636 2.017455 1.169948e+00 0.3616857999 -4.487964e-01
## 760 5.172448e-02 0.264966663 3.177330 1.018425e-01 0.9249719817 -7.902485e-01
## 761 6.826326e-02 0.156629150 2.310705 -1.151750e+00 0.3546036953 -7.745125e-01
## 762 1.646314e-06 0.110034919 2.000181 1.152621e+00 0.3682195899 -3.465724e-01
## 763 3.318627e-02 0.111296400 2.472267 -1.436548e+00 0.2644182418 -5.609401e-01
## 764 2.632057e-02 0.126846812 3.967471 1.752587e-02 0.9868629846 -3.511018e-01
## 765 8.163109e-03 0.067425665 3.850484 -6.721397e-01 0.5396649936 -2.354251e-01
## 766 3.314184e-02 0.121287824 3.195046 -7.617376e-01 0.4985141865 -4.653876e-01
## 767 1.235145e-03 0.021396832 2.442424 -1.303033e+00 0.3018126092 -1.056726e-01
## 768 1.514502e-04 0.011820340 3.714256 2.200008e-01 0.8374268376 -3.123815e-02
## 769 3.847016e-05 0.011513533 2.423524 7.828319e-01 0.5029687853 -3.308798e-02
## 770 1.395894e-03 0.024222569 2.977361 -7.641418e-01 0.5007728860 -9.592916e-02
## 771 2.000581e-04 0.072664291 2.051157 1.636103e+00 0.2403769573 -1.864082e-01
## 772 2.071865e-03 0.174078929 2.093236 9.818209e-01 0.4257381043 -5.470077e-01
## 773 9.192502e-03 0.055821863 2.067748 -1.038063e+00 0.4052117667 -2.907429e-01
## 774 1.717194e-02 0.113113735 3.956168 -3.722832e-01 0.7287652428 -3.575415e-01
## 775 3.085075e-04 0.192531301 2.011128 1.056575e+00 0.4009590852 -6.205947e-01
## 776 8.809388e-02 0.171363220 2.000099 -1.402578e+00 0.2958145263 -9.776317e-01
## 777 2.860734e-01 0.308867684 2.001739 -1.238920e+00 0.3409558770 -1.710507e+00
## 778 2.250578e-02 0.087060417 2.041366 -1.055784e+00 0.3998509384 -4.593269e-01
## 779 2.638776e-04 0.011342098 3.524074 -4.844804e-01 0.6565922732 -3.873600e-02
## 780 5.206254e-04 0.014494673 2.806742 1.960104e+00 0.1511259871 -1.956739e-02
## 781 1.718337e-03 0.025191428 2.426810 -1.131359e+00 0.3572404571 -1.205243e-01
## 782 3.526972e-03 0.039858062 3.250831 -9.970429e-01 0.3870560273 -1.612252e-01
## 783 6.621933e-03 0.047416537 2.074304 -1.657298e+00 0.2348640818 -2.757545e-01
## 784 2.848218e-04 0.033367339 2.369674 2.647429e+00 0.0988878206 -3.576590e-02
## 785 1.747360e-01 0.245281519 2.131554 -8.444390e-01 0.4825535747 -1.202462e+00
## 786 2.035753e-03 0.032942356 3.763611 -1.103296e+00 0.3353976244 -1.301186e-01
## 787 7.956924e-02 0.162876824 2.000872 -1.297611e+00 0.3238740749 -9.118607e-01
## 788 4.487382e-03 0.133229134 2.365009 3.418300e-01 0.7605181110 -4.507298e-01
## 789 1.223903e-03 0.112100329 2.134065 1.309529e+00 0.3135504348 -3.076258e-01
## 790 1.779774e-05 0.013889333 2.126785 1.975288e+00 0.1792580131 -2.903810e-02
## 791 3.342202e-02 0.105574336 2.001891 -1.714017e+00 0.2285419813 -6.347951e-01
## 792 2.997586e-03 0.049433278 3.871465 1.058516e+00 0.3513423632 -8.673876e-02
## 793 1.800898e-03 0.025864054 2.451532 -7.148939e-01 0.5366524816 -1.122661e-01
## 794 1.179195e-03 0.047443987 2.810015 2.706806e-01 0.8052882589 -1.440884e-01
## 795 1.668140e+00 0.745708126 2.000243 -1.061168e+00 0.3998045277 -3.999471e+00
## 796 2.471679e-03 0.033211381 3.215548 -3.024911e-01 0.7808007179 -1.118424e-01
## 797 2.343614e-04 0.018418029 3.098445 -1.470542e-01 0.8921394809 -6.028324e-02
## 798 3.272610e-04 0.011470128 2.790614 4.923647e-01 0.6585716565 -3.245503e-02
## 799 1.097035e-03 0.019144590 2.009155 -1.259882e+00 0.3343175715 -1.061338e-01
## 800 9.418715e-03 0.069874257 3.697410 -6.910531e-02 0.9484795555 -2.052555e-01
## 801 1.746014e-03 0.069816494 2.532575 7.134826e-01 0.5356088023 -1.974753e-01
## 802 6.404254e-05 0.018388149 2.268341 4.139997e+00 0.0430820416 5.334809e-03
## 803 2.799887e-02 0.114518585 3.392172 -1.630295e-01 0.8797337301 -3.604045e-01
## 804 1.749400e-03 0.024184522 2.012057 -1.757292e+00 0.2201947548 -1.459616e-01
## 805 1.053030e-04 0.007564890 3.804450 -2.245201e+00 0.0915608648 -3.842089e-02
## 806 5.203750e-04 0.015782729 3.465538 5.121335e-01 0.6394390771 -3.853534e-02
## 807 9.922143e-03 0.057819748 2.043222 -9.960974e-01 0.4222504499 -3.013967e-01
## 808 7.213776e-05 0.015894867 2.416145 4.442922e-01 0.6935270089 -5.119270e-02
## 809 2.120304e-02 0.084257740 2.017933 -8.148039e-01 0.5001197825 -4.281153e-01
## 810 1.802829e-02 0.107453502 3.993310 -5.287961e-02 0.9603674199 -3.042181e-01
## 811 1.233752e-03 0.295784600 2.018891 9.778332e-01 0.4304498809 -9.720866e-01
## 812 5.396828e-03 0.074286495 3.567845 9.311967e-01 0.4103626309 -1.473132e-01
## 813 9.877093e-04 0.018979358 2.373078 -1.194997e+00 0.3377944034 -9.319285e-02
## 814 6.972013e-04 0.019336246 3.776718 2.588100e-01 0.8092698479 -4.995682e-02
## 815 4.654662e-04 0.029073714 2.856021 5.563369e-01 0.6185819942 -7.904633e-02
## 816 4.173420e-04 0.039039264 2.397774 5.183976e-01 0.6481244710 -1.236642e-01
## 817 1.260373e-04 0.010325448 3.828136 2.888219e+00 0.0470580053 6.393279e-04
## 818 5.929243e-02 0.140975150 2.022231 -1.923131e+00 0.1929787673 -8.713353e-01
## 819 1.316231e-03 0.036454796 3.586137 1.292599e+00 0.2731378433 -5.887067e-02
## 820 1.209233e-03 0.050338216 2.730509 -3.782631e-01 0.7327021255 -1.885667e-01
## 821 3.737783e-04 0.051302129 2.198277 1.993833e+00 0.1727230978 -1.004242e-01
## 822 9.476510e-05 0.062431423 2.032680 6.781551e-01 0.5666322269 -2.221861e-01
## 823 1.352339e-04 0.013265340 3.231505 2.183651e+00 0.1105059406 -1.158892e-02
## 824 7.491332e-02 0.162655198 2.237133 -6.681421e-01 0.5663695280 -7.420297e-01
## 825 9.849450e-04 0.020660992 3.101543 -2.213941e-01 0.8385653002 -6.912550e-02
## 826 1.115997e-03 0.027610397 3.997687 -1.199973e+00 0.2963962633 -1.098080e-01
## 827 7.961906e-04 0.064039864 2.275446 1.549246e+00 0.2465655780 -1.467077e-01
## 828 6.129244e-04 0.118523843 2.059020 9.303193e-01 0.4479921552 -3.859467e-01
## 829 6.811267e-02 0.155373347 2.252099 -5.895181e-01 0.6092881421 -6.932814e-01
## 830 1.498413e-03 0.072005463 2.421623 2.574153e-01 0.8171274428 -2.449187e-01
## 831 8.944457e-04 0.233157163 2.022058 9.369127e-01 0.4467815318 -7.743318e-01
## 832 5.093865e-03 0.041283758 2.015062 -4.301803e-01 0.7087056736 -1.941228e-01
## 833 2.559169e-03 0.135180316 2.195404 1.014347e+00 0.4089360793 -3.976155e-01
## 834 1.072825e-03 0.052506103 2.583236 2.737554e-01 0.8046670292 -1.690604e-01
## 835 2.388865e-04 0.009032965 2.098679 2.119577e+00 0.1621405031 -1.801989e-02
## 836 3.112020e-03 0.038480960 3.445734 -5.019314e-01 0.6460626379 -1.332864e-01
## 837 1.274462e-04 0.142464750 2.008390 1.706220e+00 0.2295664856 -3.674528e-01
## 838 9.801471e-03 0.062612709 2.768973 -1.210964e+00 0.3190576281 -2.848268e-01
## 839 5.728305e-03 0.044388829 2.127516 -1.421343e+00 0.2841038793 -2.435204e-01
## 840 3.802404e-03 0.064506752 3.470029 -2.379148e-01 0.8253199563 -2.057676e-01
## 841 6.860614e-04 0.044738534 2.507531 1.388538e+00 0.2754550853 -9.746054e-02
## 842 9.370344e-03 0.070664423 3.762904 1.443186e-01 0.8926449648 -1.909705e-01
## 843 6.036344e-04 0.017389190 3.605386 -4.438363e-01 0.6824792008 -5.815526e-02
## 844 7.102714e-04 0.022056636 3.997154 1.313772e-02 0.9901474934 -6.096646e-02
## 845 9.338856e-03 0.055832864 2.005598 -1.399759e+00 0.2962136280 -3.177406e-01
## 846 1.391514e-02 0.075535326 2.874054 -7.408817e-01 0.5146328385 -3.024205e-01
## 847 1.458497e-05 0.016780978 2.070249 2.382811e+00 0.1357882909 -2.991907e-02
## 848 5.128791e-04 0.042335110 2.417146 7.653977e-01 0.5117450288 -1.227069e-01
## 849 1.633590e-02 0.076368237 2.282714 -7.336419e-01 0.5311472340 -3.485368e-01
## 850 2.685606e-03 0.086724322 2.530737 1.255750e+00 0.3126540882 -1.984281e-01
## 851 3.868080e-03 0.454166168 2.025160 8.836288e-01 0.4691125875 -1.529724e+00
## 852 9.093508e-02 0.174323488 2.010159 -1.180493e+00 0.3586595002 -9.522202e-01
## 853 7.491545e-05 0.010547377 3.068276 1.098454e-01 0.9193239663 -3.198926e-02
## 854 9.635926e-07 0.037882700 2.000895 1.768867e+00 0.2188854894 -9.591676e-02
## 855 5.308320e-03 0.042232337 2.031941 -1.899259e+00 0.1959308582 -2.592112e-01
## 856 1.535792e-01 0.227002604 2.026340 -1.088469e+00 0.3888126696 -1.211732e+00
## 857 3.219182e-03 0.071063789 3.006026 6.582761e-01 0.5572817824 -1.791208e-01
## 858 3.557003e-03 0.035978986 2.364051 -8.332467e-01 0.4804396265 -1.640410e-01
## 859 6.572331e-03 0.049702881 2.502321 -2.874399e-01 0.7958884038 -1.918394e-01
## 860 7.942922e-04 0.143474719 2.052109 7.791372e-01 0.5156532657 -4.907542e-01
## 861 3.156148e-04 0.012760499 3.685336 2.546808e-01 0.8125416574 -3.340446e-02
## 862 9.008155e-04 0.021310536 3.623425 1.404228e-01 0.8957803179 -5.868088e-02
## 863 2.368073e-02 0.100108834 3.005367 6.507460e-01 0.5615307096 -2.531240e-01
## 864 5.647685e-02 0.139587213 2.139845 -9.917442e-01 0.4199391983 -7.029411e-01
## 865 2.065647e-03 0.026433774 2.059216 -4.389888e-01 0.7024507354 -1.222620e-01
## 866 1.556863e-02 0.073834767 2.201455 -1.988063e+00 0.1733450305 -4.381782e-01
## 867 6.954279e-04 0.100241414 2.094404 1.529900e+00 0.2602300943 -2.598400e-01
## 868 1.069282e-04 0.022246215 2.308583 -2.185003e-01 0.8448670177 -8.930512e-02
## 869 8.491368e-04 0.024926910 3.968611 7.562320e-02 0.9433773857 -6.753956e-02
## 870 4.549471e-04 0.044497063 2.329507 4.885586e-01 0.6673386338 -1.459685e-01
## 871 1.662699e-04 0.045171844 2.111593 7.739490e-01 0.5161879915 -1.498794e-01
## 872 1.433277e-03 0.032356424 3.969731 -1.638365e+00 0.1772302834 -1.431183e-01
## 873 1.434123e-04 0.035892027 2.153924 1.206011e+00 0.3435537368 -1.010365e-01
## 874 1.837870e-03 0.152833628 2.107657 1.031876e+00 0.4058086963 -4.687224e-01
## 875 4.066961e-03 0.042101729 3.123829 -4.148804e-01 0.7050853775 -1.484985e-01
## 876 3.242958e-03 0.032975512 2.023675 -1.409320e+00 0.2927673502 -1.867764e-01
## 877 1.404388e-02 0.068522495 2.011994 -1.561504e+00 0.2580791572 -4.001487e-01
## 878 1.259785e-03 0.180455007 2.052247 6.440760e-01 0.5840564168 -6.415704e-01
## 879 5.219593e-05 0.014893516 2.338003 4.088042e-01 0.7171464444 -4.988494e-02
## 880 1.860191e-03 0.116630049 2.190611 8.339180e-01 0.4853862595 -3.649525e-01
## 881 7.285488e-02 0.159439716 2.186713 -7.244655e-01 0.5384101101 -7.483370e-01
## 882 8.305400e-04 0.083199344 2.166354 1.224445e+00 0.3372075689 -2.310107e-01
## 883 1.203291e-01 0.200437298 2.006523 -1.016736e+00 0.4159645459 -1.063523e+00
## 884 4.911314e-02 0.132107630 2.263069 -2.137043e+00 0.1510825691 -7.918810e-01
## 885 1.873741e-06 0.009323541 2.028946 4.559562e-01 0.6925810448 -3.532134e-02
## 886 1.258385e-03 0.021844833 2.540327 -6.488096e-01 0.5702700473 -9.138108e-02
## 887 3.462243e-03 0.048075454 3.999993 2.326667e-01 0.8274404235 -1.222934e-01
## 888 7.094671e-02 0.177730091 3.206818 -1.862961e-01 0.8633815424 -5.786399e-01
## 889 8.802723e-04 0.030658384 3.505347 -1.010747e+00 0.3767312652 -1.210623e-01
## 890 2.008260e-03 0.036387326 3.999500 3.282984e-01 0.7591548641 -8.908649e-02
## 891 1.167245e-02 0.080682942 3.852915 6.096060e-01 0.5762356746 -1.782402e-01
## 892 2.291903e-02 0.087593495 2.017248 -9.828832e-01 0.4285355777 -4.599073e-01
## 893 1.130852e-03 0.055435629 2.548519 1.445082e+00 0.2592579768 -1.153809e-01
## 894 1.092592e-04 0.029364988 2.176049 9.716536e-01 0.4265271127 -8.850741e-02
## 895 1.815717e-02 0.077843326 2.004753 -1.110286e+00 0.3822483608 -4.206013e-01
## 896 8.040186e-05 0.030169706 2.121239 2.028163e+00 0.1723880458 -6.176377e-02
## 897 3.477590e-01 0.340653771 2.004324 -1.090924e+00 0.3890016540 -1.834316e+00
## 898 2.368186e-02 0.088931631 2.007541 -1.088780e+00 0.3896001740 -4.780948e-01
## 899 8.462642e-04 0.022316069 3.930609 -6.882181e-01 0.5297775884 -7.775144e-02
## 900 5.005686e-03 0.048379144 3.386105 -1.183809e+00 0.3128829996 -2.017650e-01
## 901 4.443312e-02 0.142375688 3.298122 -8.016577e-02 0.9407261371 -4.422052e-01
## 902 3.689460e-03 0.120410878 2.367578 1.064075e+00 0.3836431117 -3.200239e-01
## 903 3.986647e-04 0.014700932 3.799399 -3.237842e-01 0.7631348686 -4.644037e-02
## 904 8.545940e-05 0.007382507 3.991791 -9.858182e-01 0.3801395794 -2.779157e-02
## 905 9.469789e-04 0.022963365 3.850226 -2.959999e-01 0.7825045940 -7.154381e-02
## 906 4.818403e-02 0.442346591 2.354858 6.145395e-01 0.5930258584 -1.381354e+00
## 907 4.483399e-04 0.012924387 2.464450 -1.606225e+00 0.2257473414 -6.744001e-02
## 908 6.340412e-03 0.058179750 3.766881 -5.788955e-01 0.5955011884 -1.992328e-01
## 909 1.763249e-03 0.044753066 3.416942 1.081061e+00 0.3499963026 -8.469922e-02
## 910 7.188511e-03 0.078295887 3.818136 -6.457447e-02 0.9517512004 -2.265852e-01
## 911 2.336202e-03 0.027962005 2.016126 -3.808654e+00 0.0617542962 -2.258909e-01
## 912 3.456088e-03 0.056680798 3.703727 1.092341e+00 0.3405886677 -1.005476e-01
## 913 1.730065e-04 0.016314422 3.027769 1.086581e+00 0.3560688370 -3.392448e-02
## 914 3.215997e-03 0.107319270 2.406235 7.861748e-01 0.5017763625 -3.101674e-01
## 915 6.783396e-05 0.149517138 2.004050 9.310600e-01 0.4499425333 -5.028667e-01
## 916 2.855037e-03 0.037695422 3.586603 -2.166570e-01 0.8402312554 -1.177598e-01
## 917 2.850310e-03 0.031522258 2.182961 -7.486270e-01 0.5263993678 -1.488961e-01
## 918 2.871330e-02 0.150487097 3.906469 2.809395e-01 0.7930063191 -3.795164e-01
## 919 7.242541e-03 0.066291729 3.961405 3.746469e-02 0.9719263264 -1.822811e-01
## 920 9.187181e-06 0.003598050 3.130823 1.040623e+00 0.3716435613 -7.440408e-03
## 921 1.005400e-02 0.301418253 2.152977 7.788651e-01 0.5125123739 -9.777099e-01
## 922 3.950692e-04 0.030763278 2.630112 5.213602e-01 0.6427857429 -9.013317e-02
## 923 6.676496e-05 0.094060090 2.010087 1.181348e+00 0.3583895108 -2.916502e-01
## 924 2.084814e-04 0.011081602 3.931698 -8.604758e-02 0.9356319410 -3.193295e-02
## 925 5.639623e-03 0.045065053 2.319206 -1.310378e+00 0.3047551124 -2.294942e-01
## 926 3.357127e-03 0.037960549 3.062863 -4.825272e-01 0.6618224534 -1.377337e-01
## 927 8.702411e-04 0.027845920 3.761531 6.571838e-01 0.5490891942 -6.098468e-02
## 928 9.775037e-04 0.018493200 2.197944 -8.790478e-01 0.4648048843 -8.933868e-02
## 929 4.276102e-03 0.137672487 2.323135 5.163706e-01 0.6506080732 -4.489112e-01
## 930 1.428597e-02 0.075791597 2.791497 -1.508939e+00 0.2349916819 -3.660869e-01
## 931 5.282528e-04 0.017239049 3.867609 -2.647882e-01 0.8046821309 -5.308110e-02
## 932 3.366157e-04 0.086112477 2.061441 1.680939e+00 0.2310827273 -2.153783e-01
## 933 6.481499e-04 0.045604639 2.457544 8.921939e-01 0.4509204056 -1.243654e-01
## 934 9.466179e-05 0.057334191 2.038765 1.355253e+00 0.3059503190 -1.645460e-01
## 935 1.558492e-02 0.072538860 2.051514 -3.632987e+00 0.0655620355 -5.682510e-01
## 936 6.801230e-05 0.076979550 2.015362 2.464695e+00 0.1316917538 -1.390776e-01
## 937 9.468303e-04 0.027839192 3.866877 1.123760e+00 0.3259962810 -4.707025e-02
## 938 1.053492e-03 0.037288415 3.213086 8.466116e-01 0.4556193495 -8.276931e-02
## 939 4.506363e-02 0.286314845 2.854389 5.818972e-01 0.6033910522 -7.714446e-01
## 940 2.125466e-03 0.136890784 2.156932 9.164076e-01 0.4500808929 -4.243267e-01
## 941 2.974318e-03 0.031524190 2.009422 -2.115538e+00 0.1680520047 -2.017206e-01
## 942 1.347277e-03 0.032358911 3.920702 8.727157e-01 0.4330048316 -6.232380e-02
## 943 3.852864e-02 0.145627391 3.829238 -9.186020e-02 0.9314125969 -4.249150e-01
## 944 9.390268e-06 0.025644892 2.019128 1.572418e+00 0.2553292932 -6.902089e-02
## 945 5.329306e-03 0.043750252 2.308095 -7.288914e-01 0.5329003183 -1.979885e-01
## 946 4.372055e-04 0.012801744 2.490542 -5.977429e-01 0.5999212944 -5.353855e-02
## 947 6.913421e-04 0.026952043 3.528568 1.211378e+00 0.3005835110 -4.629449e-02
## 948 2.528018e-01 0.290736050 2.012350 -1.098853e+00 0.3858396873 -1.563085e+00
## 949 5.313817e-06 0.017348939 2.023678 8.109895e-01 0.5016728297 -5.974589e-02
## 950 2.357310e-02 0.100075208 3.021229 -1.090954e+00 0.3545698485 -4.263992e-01
## 951 7.074136e-06 0.004477935 2.523774 4.362188e+00 0.0315028731 3.633889e-03
## 952 3.148830e-01 0.325864491 2.046741 -9.966606e-01 0.4218798083 -1.696617e+00
## 953 2.592052e-04 0.015061700 3.785120 1.605372e+00 0.1876901482 -1.859145e-02
## 954 4.257003e-03 0.039953800 2.492119 -1.796798e+00 0.1886297484 -2.149336e-01
## 955 1.947884e-01 0.255484080 2.021108 -9.859165e-01 0.4271787999 -1.340217e+00
## 956 1.797419e-03 0.084714505 2.361364 6.232515e-01 0.5880221691 -2.631336e-01
## 957 2.143742e-03 0.030694958 3.156690 2.336392e-01 0.8296038654 -8.782690e-02
## 958 7.793074e-04 0.027805722 3.611398 1.321807e-01 0.9018729543 -7.691486e-02
## 959 9.761569e-05 0.058575368 2.038294 1.267220e+00 0.3306167817 -1.733181e-01
## 960 3.402339e-03 0.033719884 2.010290 -9.559743e-01 0.4395290524 -1.766109e-01
## 961 2.045693e-03 0.086872466 2.393441 6.661652e-01 0.5637954707 -2.627863e-01
## 962 1.300534e-03 0.021647338 2.321720 -1.689399e+00 0.2156424500 -1.183741e-01
## 963 1.117876e-03 0.022892098 3.395093 6.282144e-02 0.9534283068 -6.684568e-02
## 964 3.538460e-04 0.013344898 3.618663 -3.183204e-01 0.7677538438 -4.289117e-02
## 965 1.886092e-01 0.298155066 3.413645 1.563631e-02 0.9883945397 -8.823582e-01
## 966 7.331807e-04 0.035264007 2.923167 4.639497e-02 0.9659822532 -1.122771e-01
## 967 1.431495e-02 0.124326595 3.489249 3.813600e-01 0.7249989334 -3.186429e-01
## 968 2.209901e-05 0.083472887 2.004233 1.935672e+00 0.1922772998 -1.968527e-01
## 969 5.211389e-04 0.026430094 3.193220 1.585349e+00 0.2056017929 -3.940419e-02
## 970 3.472142e-03 0.035779775 2.419720 -9.377939e-01 0.4322163529 -1.645421e-01
## 971 7.651146e-04 0.017551452 2.797046 -2.615883e+00 0.0852369063 -1.041334e-01
## 972 2.818434e-02 0.177827081 3.434400 1.783378e-01 0.8684704061 -4.957952e-01
## 973 9.277493e-03 0.088173231 3.839505 1.965050e-01 0.8541749201 -2.315707e-01
## 974 4.644317e-04 0.058770609 2.187284 1.430947e+00 0.2786508819 -1.491155e-01
## 975 3.868835e-02 0.126229049 2.892665 -5.623706e-01 0.6144878446 -4.812704e-01
## 976 5.788417e-02 0.144221868 2.310161 -6.158200e-01 0.5932472309 -6.359693e-01
## 977 1.276867e-02 0.068031419 2.347001 -4.882484e-01 0.6672452781 -2.881313e-01
## 978 2.016913e-01 0.263208596 2.121755 -7.388134e-01 0.5330929740 -1.266904e+00
## 979 1.035372e-04 0.025567942 2.222255 1.482324e+00 0.2644447348 -6.221081e-02
## 980 6.993208e-04 0.016374434 2.587585 -2.570888e+00 0.0956649806 -9.923635e-02
## 981 2.064687e-03 0.096426215 2.317713 4.511039e-01 0.6906667261 -3.213838e-01
## 982 2.554997e-02 0.102280689 2.868095 -6.901975e-01 0.5417575141 -4.047316e-01
## 983 9.761581e-04 0.029728316 3.740038 5.336323e-02 0.9601698445 -8.326522e-02
## 984 7.388055e-04 0.110452049 2.082375 1.354220e+00 0.3038853713 -3.080919e-01
## 985 3.046373e-03 0.032976694 2.282215 -1.677858e+00 0.2197672219 -1.816616e-01
## 986 2.267224e+00 0.869342563 2.000081 -9.354135e-01 0.4483196263 -4.553529e+00
## 987 8.089550e-02 0.164211754 2.000049 -8.850866e-01 0.4694806065 -8.518711e-01
## 988 7.050257e-04 0.015485437 2.081498 -1.291116e+01 0.0050918629 -2.641249e-01
## 989 1.198750e-04 0.030112568 2.184002 1.696328e+00 0.2213107220 -6.856483e-02
## 990 2.505835e-02 0.091596173 2.017755 -1.063163e+00 0.3982585553 -4.881835e-01
## 991 1.204642e-01 0.207103528 2.271400 -8.095316e-01 0.4942704618 -9.641080e-01
## 992 1.728903e-03 0.182929493 2.070073 1.124616e+00 0.3742048585 -5.563679e-01
## 993 1.726234e-01 0.240192884 2.010531 -1.000277e+00 0.4220711684 -1.268556e+00
## 994 7.440530e-02 0.159212372 2.088146 -8.641750e-01 0.4752455902 -7.956444e-01
## 995 1.860917e-02 0.097057475 3.634799 1.635945e-01 0.8787372332 -2.646179e-01
## 996 1.210310e-02 0.064090655 2.072597 -1.382892e+00 0.2968319909 -3.553378e-01
## 997 1.944443e-01 0.254940906 2.011114 -9.058690e-01 0.4601656970 -1.322077e+00
## 998 3.105215e-04 0.050534032 2.168678 1.228281e+00 0.3359125182 -1.399318e-01
## 999 1.456637e-03 0.027296492 3.663021 -3.090306e-01 0.7740670211 -8.705309e-02
## 1000 1.174005e-04 0.018153414 2.529392 1.371360e+00 0.2792335219 -3.946099e-02
## conf.high mean.null alternative conf.level
## 1 0.0369856030 0 two.sided 0.95
## 2 0.2785766850 0 two.sided 0.95
## 3 1.1645248334 0 two.sided 0.95
## 4 1.2413859875 0 two.sided 0.95
## 5 4.8010485072 0 two.sided 0.95
## 6 0.1668231442 0 two.sided 0.95
## 7 0.4213722977 0 two.sided 0.95
## 8 0.0524120130 0 two.sided 0.95
## 9 1.0739799962 0 two.sided 0.95
## 10 0.2250104970 0 two.sided 0.95
## 11 0.5274576553 0 two.sided 0.95
## 12 0.4766153982 0 two.sided 0.95
## 13 3.1280602357 0 two.sided 0.95
## 14 0.9493419055 0 two.sided 0.95
## 15 0.6742726613 0 two.sided 0.95
## 16 0.0524657047 0 two.sided 0.95
## 17 0.3413920810 0 two.sided 0.95
## 18 0.6409031421 0 two.sided 0.95
## 19 0.1256729757 0 two.sided 0.95
## 20 0.5001374784 0 two.sided 0.95
## 21 0.7951479057 0 two.sided 0.95
## 22 2.7592586705 0 two.sided 0.95
## 23 0.4209411458 0 two.sided 0.95
## 24 3.5537626215 0 two.sided 0.95
## 25 3.7679354815 0 two.sided 0.95
## 26 0.4752086115 0 two.sided 0.95
## 27 0.0516077895 0 two.sided 0.95
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Agregar a nuestra base de datos el valor de p(VP) y el factor de cambio o fold change (2DDCT)
Datos_estadistica2 <- Datos_estadistica %>%
mutate(PV= Prueba_t$pvalue,
FC=DCT$DosDDCT,
LogVP=-log10(PV),
LogFC=log2(FC)) %>% #control+shift+M
select(-2:-7)#quitar de la columna 2 a la 7
Datos_estadistica2
## # A tibble: 1,000 × 5
## Gen PV FC LogVP LogFC
## <chr> <dbl> <dbl> <dbl> <dbl>
## 1 Gene_1 0.0687 3.69 1.16 1.88
## 2 Gene_2 0.403 2.59 0.395 1.37
## 3 Gene_3 0.187 30.6 0.728 4.94
## 4 Gene_4 0.250 30.9 0.602 4.95
## 5 Gene_5 0.541 3.59 0.266 1.84
## 6 Gene_6 0.250 5.36 0.602 2.42
## 7 Gene_7 0.963 0.955 0.0162 -0.0670
## 8 Gene_8 0.114 2.79 0.945 1.48
## 9 Gene_9 0.257 21.9 0.591 4.46
## 10 Gene_10 0.206 3.82 0.687 1.93
## # ℹ 990 more rows
#primer valor: p value; = base de datos de donde sacar______ $:selecciona columa
Gráfica de vulcano
V_plot <- ggplot(Datos_estadistica2,
aes(x=LogFC,
y=LogVP))+
geom_point() + #tipo de grafica
labs(title = "Gráfica de Volcano",
subtitle = "Análisis de datos masivos",
caption= "Diseño:Paulina Aguilar",
x="Log2(FC)",
y="-Log10(VP)")
V_plot
Ahora a decirle a copilot Mejorar grafica: Estoy haciendo esta grafica y
quiero que me la mejores poniendo una linea de corte en y con valor de
-log10(0.05). quiero dos lineas verticales que esten en 1.5 y -1.5.
quiero que los puntos sean grises pero aquellos arriba de -log10(0.05)
sean de color, pon a aquellos a la derecha de 1.5 del eje x de color
rojo y aquellos a la izquierda de -1.5 de color azul.
V_plot <- ggplot(Datos_estadistica2, aes(x = LogFC, y = LogVP)) + # puntos con colores según criterios
geom_point(aes(color = case_when( LogVP > -log10(0.05) & LogFC > 1.5 ~ "red", LogVP > -log10(0.05) & LogFC < -1.5 ~ "blue", TRUE ~ "grey" ))) + scale_color_identity() + # usa los colores definidos directamente
# lÃneas de corte
geom_hline(yintercept = -log10(0.05), linetype = "dashed", color = "black") + geom_vline(xintercept = c(-1.5, 1.5), linetype = "dashed", color = "black") + labs(title = "Gráfica de Volcano", subtitle = "Análisis de datos masivos", caption = "Diseño: Paulina Aguilar", x = "Log2(FC)", y = "-Log10(VP)") + theme_minimal()
V_plot
abajo de la linea horizontal: no son significativos. izq y derecha: son
solo relevantes Guardar imagen
# Guardar en formato PNG
ggsave("Volcano_plot.png", plot = V_plot, width = 8, height = 6, dpi = 300)
# Guardar en formato PDF
ggsave("Volcano_plot.pdf", plot = V_plot, width = 8, height = 6)