Time: ~30 minutes
Goal: Practice correlation analysis from start to finish using real public health data
Learning Objectives:
Structure:
Submission: Publish to RPubs and submit your .Rmd file + RPubs link to Brightspace by end of class
Correlation measures the strength and direction of the LINEAR relationship between two continuous variables.
✅ Use correlation when:
❌ Don’t use when:
⚠️ CORRELATION ≠ CAUSATION
Just because two variables are correlated does NOT mean one causes the other!
Classic Example: Ice cream sales and drowning deaths are highly correlated. Does ice cream cause drowning? NO! Both increase in summer (confounding by temperature/season).
# Load NHANES data
data(NHANES)
# Select adult participants with complete data
nhanes_adult <- NHANES %>%
filter(Age >= 18, Age <= 80) %>%
select(Age, Weight, Height, BMI, BPSysAve, BPDiaAve,
Pulse, PhysActive, SleepHrsNight) %>%
na.omit()
# Display sample
# Display sample size
data.frame(
Metric = "Sample Size",
Value = paste(nrow(nhanes_adult), "adults")
) %>%
kable()| Metric | Value |
|---|---|
| Sample Size | 7133 adults |
| Age | Weight | Height | BMI | BPSysAve | BPDiaAve | Pulse | PhysActive | SleepHrsNight |
|---|---|---|---|---|---|---|---|---|
| 34 | 87.4 | 164.7 | 32.2 | 113 | 85 | 70 | No | 4 |
| 34 | 87.4 | 164.7 | 32.2 | 113 | 85 | 70 | No | 4 |
| 34 | 87.4 | 164.7 | 32.2 | 113 | 85 | 70 | No | 4 |
| 49 | 86.7 | 168.4 | 30.6 | 112 | 75 | 86 | No | 8 |
| 45 | 75.7 | 166.7 | 27.2 | 118 | 64 | 62 | Yes | 8 |
| 45 | 75.7 | 166.7 | 27.2 | 118 | 64 | 62 | Yes | 8 |
| 45 | 75.7 | 166.7 | 27.2 | 118 | 64 | 62 | Yes | 8 |
| 66 | 68.0 | 169.5 | 23.7 | 111 | 63 | 60 | Yes | 7 |
Dataset Description:
Age: Age in yearsWeight: Weight in kgBMI: Body Mass Index (kg/m²)BPSysAve: Average systolic blood pressure (mmHg)BPDiaAve: Average diastolic blood pressure (mmHg)Pulse: 60 second pulse rateSleepHrsNight: Hours of sleep per nightIs there a correlation between age and systolic blood pressure among US adults?
Public Health Context: Understanding age-related changes in blood pressure helps identify at-risk populations and inform screening guidelines.
Always start with a scatterplot!
# Create scatterplot
ggplot(nhanes_adult, aes(x = Age, y = BPSysAve)) +
geom_point(alpha = 0.3, color = "steelblue") +
geom_smooth(method = "lm", se = TRUE, color = "red") +
labs(
title = "Age vs Systolic Blood Pressure",
subtitle = "NHANES Data, Adults 18-80 years",
x = "Age (years)",
y = "Systolic Blood Pressure (mmHg)"
) +
theme_minimal()What we observe:
# Calculate Pearson correlation
cor_age_bp <- cor.test(nhanes_adult$Age, nhanes_adult$BPSysAve)
# Display results in clean table
tidy(cor_age_bp) %>%
select(estimate, statistic, p.value, conf.low, conf.high) %>%
kable(
digits = 3,
col.names = c("r", "t-statistic", "p-value", "95% CI Lower", "95% CI Upper"),
caption = "Pearson Correlation: Age and Systolic BP"
)| r | t-statistic | p-value | 95% CI Lower | 95% CI Upper |
|---|---|---|---|---|
| 0.415 | 38.54 | 0 | 0.396 | 0.434 |
Hypothesis Test:
Results:
# Calculate r-squared
r_squared <- cor_age_bp$estimate^2
data.frame(
Measure = c("Correlation (r)", "Coefficient of Determination (r²)",
"Variance Explained"),
Value = c(
round(cor_age_bp$estimate, 3),
round(r_squared, 3),
paste0(round(r_squared * 100, 1), "%")
)
) %>%
kable(caption = "Summary of Correlation Strength")| Measure | Value |
|---|---|
| Correlation (r) | 0.415 |
| Coefficient of Determination (r²) | 0.172 |
| Variance Explained | 17.2% |
Interpretation:
There is a statistically significant moderate positive correlation between age and systolic blood pressure. As age increases, systolic BP tends to increase. However, age explains only about 17.2% of the variation in BP, suggesting other factors also play important roles.
Public Health Implication: Age-appropriate BP screening is important, but individual risk assessment should consider multiple factors beyond age alone.
Assumption 1: Linearity (already checked with scatterplot ✓)
Assumption 2: Bivariate Normality
# Q-Q plots for normality
par(mfrow = c(1, 2))
qqnorm(nhanes_adult$Age, main = "Q-Q Plot: Age")
qqline(nhanes_adult$Age, col = "red")
qqnorm(nhanes_adult$BPSysAve, main = "Q-Q Plot: Systolic BP")
qqline(nhanes_adult$BPSysAve, col = "red")Assessment: Both variables are approximately normally distributed (points follow the red line reasonably well). Some deviation in the tails, but with large sample size (n = 7133), the correlation test is robust to minor violations.
Assumption 3: No Extreme Outliers (scatterplot shows no extreme outliers ✓)
Is BMI correlated with diastolic blood pressure?
Why this matters: Understanding the relationship between obesity and blood pressure helps inform weight management interventions.
ggplot(nhanes_adult, aes(x = BMI, y = BPDiaAve)) +
geom_point(alpha = 0.3, color = "darkgreen") +
geom_smooth(method = "lm", se = TRUE, color = "red", fill = "pink") +
labs(
title = "BMI vs Diastolic Blood Pressure",
x = "Body Mass Index (kg/m²)",
y = "Diastolic Blood Pressure (mmHg)"
) +
theme_minimal()Observation: Positive relationship visible, moderate scatter around the line.
# Pearson correlation
cor_bmi_bp <- cor.test(nhanes_adult$BMI, nhanes_adult$BPDiaAve)
# Display results
tidy(cor_bmi_bp) %>%
select(estimate, statistic, p.value, conf.low, conf.high) %>%
kable(
digits = 3,
col.names = c("r", "t-statistic", "p-value", "95% CI Lower", "95% CI Upper"),
caption = "Pearson Correlation: BMI and Diastolic BP"
)| r | t-statistic | p-value | 95% CI Lower | 95% CI Upper |
|---|---|---|---|---|
| 0.117 | 9.966 | 0 | 0.094 | 0.14 |
# Calculate r-squared
r_squared_bmi <- cor_bmi_bp$estimate^2
data.frame(
Measure = c("r²", "Variance Explained"),
Value = c(
round(r_squared_bmi, 4),
paste0(round(r_squared_bmi * 100, 2), "%")
)
) %>%
kable(caption = "Effect Size")| Measure | Value | |
|---|---|---|
| cor | r² | 0.0137 |
| Variance Explained | 1.37% |
Interpretation:
Key Insight: While BMI and blood pressure are related, BMI alone explains less than 10% of BP variation. Other factors (genetics, diet, physical activity, stress, age) play substantial roles.
How are cardiovascular health indicators related to each other?
# Select cardiovascular variables
cardio_vars <- nhanes_adult %>%
select(Age, BMI, BPSysAve, BPDiaAve, Pulse)
# Calculate correlation matrix
cor_matrix <- cor(cardio_vars, use = "complete.obs")
# Display as table
cor_matrix %>%
kable(digits = 3, caption = "Cardiovascular Health Correlation Matrix")| Age | BMI | BPSysAve | BPDiaAve | Pulse | |
|---|---|---|---|---|---|
| Age | 1.000 | 0.065 | 0.415 | -0.019 | -0.153 |
| BMI | 0.065 | 1.000 | 0.135 | 0.117 | 0.112 |
| BPSysAve | 0.415 | 0.135 | 1.000 | 0.340 | -0.022 |
| BPDiaAve | -0.019 | 0.117 | 0.340 | 1.000 | 0.106 |
| Pulse | -0.153 | 0.112 | -0.022 | 0.106 | 1.000 |
# Create correlation plot
corrplot(cor_matrix,
method = "circle",
type = "lower",
tl.col = "black",
tl.srt = 45,
addCoef.col = "black",
number.cex = 0.7,
col = colorRampPalette(c("#3498db", "white", "#e74c3c"))(200),
title = "Cardiovascular Health Correlations",
mar = c(0,0,2,0))Key Findings:
# Create summary table of notable correlations
data.frame(
Relationship = c(
"Systolic BP & Diastolic BP",
"Age & Systolic BP",
"Age & Diastolic BP",
"BMI & Systolic BP",
"BMI & Pulse"
),
Correlation = c(
round(cor_matrix["BPSysAve", "BPDiaAve"], 3),
round(cor_matrix["Age", "BPSysAve"], 3),
round(cor_matrix["Age", "BPDiaAve"], 3),
round(cor_matrix["BMI", "BPSysAve"], 3),
round(cor_matrix["BMI", "Pulse"], 3)
),
Strength = c("Strong", "Moderate", "Weak-Moderate", "Moderate", "Very Weak")
) %>%
kable(caption = "Notable Correlations Summary")| Relationship | Correlation | Strength |
|---|---|---|
| Systolic BP & Diastolic BP | 0.340 | Strong |
| Age & Systolic BP | 0.415 | Moderate |
| Age & Diastolic BP | -0.019 | Weak-Moderate |
| BMI & Systolic BP | 0.135 | Moderate |
| BMI & Pulse | 0.112 | Very Weak |
Interpretation: Systolic and diastolic BP show the strongest correlation (r = 0.34), which makes sense as they measure the same physiological process. Pulse rate shows relatively weak correlations, suggesting it’s influenced by different factors.
Use Spearman’s rank correlation when:
# Visualize relationship
ggplot(nhanes_adult, aes(x = Age, y = Pulse)) +
geom_point(alpha = 0.3, color = "purple") +
geom_smooth(method = "lm", se = TRUE, color = "red") +
labs(
title = "Age vs Pulse Rate",
x = "Age (years)",
y = "Pulse Rate (bpm)"
) +
theme_minimal()# Calculate both correlations
pearson_r <- cor.test(nhanes_adult$Age, nhanes_adult$Pulse, method = "pearson")
spearman_r <- cor.test(nhanes_adult$Age, nhanes_adult$Pulse, method = "spearman")
# Compare in table
data.frame(
Method = c("Pearson", "Spearman"),
Correlation = c(
round(pearson_r$estimate, 3),
round(spearman_r$estimate, 3)
),
p_value = c(
format.pval(pearson_r$p.value),
format.pval(spearman_r$p.value)
),
Difference = c(
"—",
round(abs(pearson_r$estimate - spearman_r$estimate), 3)
)
) %>%
kable(caption = "Pearson vs Spearman Comparison")| Method | Correlation | p_value | Difference | |
|---|---|---|---|---|
| cor | Pearson | -0.153 | < 2.22e-16 | — |
| rho | Spearman | -0.162 | < 2.22e-16 | 0.008 |
Interpretation:
Now it’s your turn to practice! Use the same NHANES dataset and follow the examples above.
Total Points: 25 points
Research Question: Is there a correlation between weight and height among US adults?
Your tasks:
cor.test() and
display with tidy() (3 points)# YOUR CODE HERE
# Load NHANES data
data(NHANES)
# Select adult participants with complete data
nhanes_adult <- NHANES %>%
filter(Age >= 18, Age <= 80) %>%
select(Age, Weight, Height) %>%
na.omit()
# Display sample
# Display sample size
data.frame(
Metric = "Sample Size",
Value = paste(nrow(nhanes_adult), "adults")
) %>%
kable()
head(nhanes_adult, 8) %>%
kable(digits = 1, caption = "NHANES Adult Data Sample")
# a. Scatterplot
# Create scatterplot
ggplot(nhanes_adult, aes(x = Height, y = Weight)) +
geom_point(alpha = 0.3, color = "steelblue") +
geom_smooth(method = "lm", se = TRUE, color = "red") +
labs(
title = "Height vs Weight",
subtitle = "NHANES Data, Adults 18-80 years",
x = "Height (cm)",
y = "Weight (kg)"
) +
theme_minimal()
# b. Correlation test with tidy() display
# Calculate Pearson correlation
cor_height_weight <- cor.test(nhanes_adult$Height, nhanes_adult$Weight)
# Display results in clean table
tidy(cor_height_weight) %>%
select(estimate, statistic, p.value, conf.low, conf.high) %>%
kable(
digits = 3,
col.names = c("r", "t-statistic", "p-value", "95% CI Lower", "95% CI Upper"),
caption = "Pearson Correlation: Height and Weight"
)
# c. Statistical significance
# Calculate r-squared
r_squared <- cor_height_weight$estimate^2
data.frame(
Measure = c("Correlation (r)", "Coefficient of Determination (r²)",
"Variance Explained"),
Value = c(
round(cor_height_weight$estimate, 3),
round(r_squared, 3),
paste0(round(r_squared * 100, 1), "%")
)
) %>%
kable(caption = "Summary of Correlation Strength")
# d. r² and interpretation (write as comment)
# Interpretation:
# There is a statistically significant moderate positive correlation between height and weight (r = 0.45, p < .001). This shows that taller people tend to weigh more. The coefficient of determination (r² = 0.202) shows that approximately 20.2% of the variation in weight is explained by height. Height is a predictor of weight, but the majority of the variation is due to other factors such as diet and physical activity.Research Question: What are the relationships among BMI, weight, and height?
Your tasks:
# YOUR CODE HERE
# Select adult participants with complete data
nhanes_adult <- NHANES %>%
filter(Age >= 18, Age <= 80) %>%
select(Weight, Height, BMI) %>%
na.omit()
# a. Correlation matrix
# Replace cardiovascular variables
bmi_vars <- nhanes_adult %>%
select(Weight, Height, BMI)
# Calculate correlation matrix
cor_matrix <- cor(bmi_vars, use = "complete.obs")
# Display as table
cor_matrix %>%
kable(digits = 3, caption = "Correlation Matrix for Weight, Height and BMI")
# b. Visualize with corrplot
# Create correlation plot
corrplot(cor_matrix,
method = "circle",
type = "upper",
tl.col = "black",
tl.srt = 45,
addCoef.col = "black",
number.cex = 0.7,
col = colorRampPalette(c("#3498db", "white", "#e74c3c"))(200),
title = "Correlations Within Weight, Height, and BMI",
mar = c(0,0,2,0))
# c. Strongest correlation:
# Create summary table of notable correlations
data.frame(
Relationship = c(
"Weight & BMI",
"Height & Weight",
"Height & BMI"
),
Correlation = c(
round(cor_matrix["Weight", "BMI"], 3),
round(cor_matrix["Height", "Weight"], 3),
round(cor_matrix["Height", "BMI"], 3)
),
Strength = c("Strong", "Moderate", "Weak")
) %>%
kable(caption = "Correlation Summary for Weight, Height, and BMI")
# d. Explanation (write as comment)
# Weight and BMI show the strongest correlation since r =0.880.This makes sense mathematically because BMI is calculated by dividing the weight by the height squared.Since weight is directly used in the BMI formula, increases in weight lead to increases in BMI, showing a strong positive relationship. Biologically, greater body mass contributes to higher BMI values.Research Question: Is there a relationship between hours of sleep and age?
Your tasks:
tidy()
(2 points)# YOUR CODE HERE
# Select adult participants with complete data
nhanes_adult <- NHANES %>%
filter(Age >= 18, Age <= 80) %>%
select(Age, SleepHrsNight) %>%
na.omit()
# a. Scatterplot
# Create scatterplot
ggplot(nhanes_adult, aes(x = Age, y = SleepHrsNight)) +
geom_point(alpha = 0.3, color = "steelblue") +
geom_smooth(method = "lm", se = TRUE, color = "red") +
labs(
title = "Age vs Hours of Sleep",
subtitle = "NHANES Data, Adults 18-80 years",
x = "Age (years)",
y = "Hours of Sleep A Night"
) +
theme_minimal()
# b. Correlation with tidy()
# Calculate Pearson correlation
cor_age_sleep <- cor.test(nhanes_adult$Age, nhanes_adult$SleepHrsNight)
# Display results in clean table
tidy(cor_age_sleep) %>%
select(estimate, statistic, p.value, conf.low, conf.high) %>%
kable(
digits = 3,
col.names = c("r", "t-statistic", "p-value", "95% CI Lower", "95% CI Upper"),
caption = "Pearson Correlation: Age and Hours of Sleep"
)
# c. Interpretation (write as comment)
# # The correlation between age and hours of sleep is weak # (r = 0.022) and not statistically significant since the p-value is greater than 0.05. There is no statistically significant linear relationship between age and hours of sleep in the sample.Challenge: Investigate the relationship between two variables of your choice from the NHANES dataset. Include:
# Select adult participants with complete data
nhanes_adult <- NHANES %>%
filter(Age >= 18, Age <= 80) %>%
select(Age, BMI) %>%
na.omit()
# Dataset
age_bmi_data <- nhanes_adult %>%
select(Age, BMI) %>%
na.omit()
# Scatterplot
ggplot(age_bmi_data, aes(x = Age, y = BMI)) +
geom_point(alpha = 0.3, color = "steelblue") +
geom_smooth(method = "lm", se = TRUE, color = "red") +
labs(
title = "Age vs Body Mass Index (BMI)",
subtitle = "NHANES Data, Adults 18-80 years",
x = "Age (years)",
y = "Body Mass Index (BMI)"
) +
theme_minimal()# Correlation test
cor_age_bmi <- cor.test(age_bmi_data$Age, age_bmi_data$BMI)
tidy(cor_age_bmi) %>%
select(estimate, statistic, p.value, conf.low, conf.high) %>%
kable(
digits = 3,
col.names = c("r", "t-statistic", "p-value",
"95% CI Lower", "95% CI Upper"),
caption = "Pearson Correlation for Age and BMI"
)| r | t-statistic | p-value | 95% CI Lower | 95% CI Upper |
|---|---|---|---|---|
| 0.064 | 5.478 | 0 | 0.041 | 0.086 |
# Q-Q plots for normality
par(mfrow = c(1, 2))
qqnorm(nhanes_adult$Age, main = "Q-Q Plot: Age")
qqline(nhanes_adult$Age, col = "red")
qqnorm(nhanes_adult$BMI, main = "Q-Q Plot: BMI")
qqline(nhanes_adult$BMI, col = "red")par(mfrow = c(1, 1))
#Interpretation
#There is a statistically significant positive correlation between age and BMI since r = 0.064 and p < .001. However, the correlation itself is weak, showing that age explains very little variation in BMI. Assumption checks show the relationship is approximately linear. While the Q-Q plots display some deviation from perfect normality, Pearson correlation is robust with large sample sizes, proving that the test results are reliable.Save your work with your name:
Correlation_Lab_YourName.Rmd
Knit to HTML to create your report
Publish to RPubs:
Submit to Brightspace:
Due: End of class today
Grading: This lab is worth 15% of your in-class lab grade. The lowest 2 lab grades are dropped.
cor.test() - Calculate correlation and test
significancetidy() - Clean display of statistical test resultscor() - Calculate correlation matrixcorrplot() - Visualize correlation matrixggplot() + geom_point() - Scatterplotsgeom_smooth(method="lm") - Add fitted regression
lineqqnorm() / qqline() - Check normality?cor.test in
consoleRemember:
✓ Correlation measures LINEAR relationships only
✓ Always visualize your data first
✓ Correlation ≠ Causation
✓ Check your assumptions
✓ Consider confounding and alternative explanations
This lab activity was created for EPI 553: Principles of
Statistical Inference II
University at Albany, College of Integrated Health
Sciences
Spring 2026