Characteristic Censored
N = 2,198
1
Death
N = 88
1
Relapse
N = 314
1
p-value2
Demographics
Social Vulnerability mobility


0.041
    Consistently low 395 (18%) 24 (27%) 68 (22%)
    Consistently moderate 389 (18%) 9 (10%) 48 (15%)
    Decreasing 313 (14%) 17 (19%) 42 (13%)
    Increasing 549 (25%) 25 (28%) 86 (27%)
    Consistently high 552 (25%) 13 (15%) 70 (22%)
Gender


>0.9
    Female 956 (44%) 38 (43%) 133 (42%)
    Male 1,241 (56%) 50 (57%) 181 (58%)
Age at diagnosis (years)


<0.001
    1-4 538 (24%) 6 (6.8%) 59 (19%)
    5-9 909 (41%) 20 (23%) 132 (42%)
    10-14 562 (26%) 48 (55%) 95 (30%)
    15-21 189 (8.6%) 14 (16%) 28 (8.9%)
Race/Ethnicity


0.001
    Non-Hispanic White 1,512 (69%) 51 (58%) 194 (62%)
    Non-Hispanic Black 132 (6.0%) 7 (8.0%) 35 (11%)
    Hispanic (All races) 392 (18%) 25 (28%) 67 (21%)
    Other 162 (7.4%) 5 (5.7%) 18 (5.7%)
Medical insurance provider


0.060
    Private 1,510 (69%) 56 (64%) 192 (61%)
    Public 469 (21%) 24 (27%) 80 (25%)
    Other/Unknown 219 (10.0%) 8 (9.1%) 42 (13%)
Clinical characteristics
ALL subtype


<0.001
    Standard-risk B-cell ALL 1,124 (51%) 12 (14%) 127 (40%)
    High-risk B-cell ALL 706 (32%) 59 (67%) 139 (44%)
    T-cell ALL 368 (17%) 17 (19%) 48 (15%)
WBC count at diagnosis


<0.001
    <50,000/ul 1,818 (83%) 53 (62%) 222 (71%)
    >=50,000/ul 375 (17%) 33 (38%) 92 (29%)
CNS involvement


0.053
    CNS1-2 2,149 (98%) 83 (97%) 302 (96%)
    CNS3 38 (1.7%) 3 (3.5%) 11 (3.5%)
Cytogenetics


<0.001
    Favorable 877 (40%) 6 (6.8%) 57 (18%)
    Neutral 804 (37%) 51 (58%) 157 (50%)
    Unfavorable 149 (6.8%) 14 (16%) 52 (17%)
    Missing 368 (17%) 17 (19%) 48 (15%)
P values: Pearson chi-square (no continuity correction) for categorical variables; Fisher’s exact test for CNS group (sparse counts). Missing data (not shown in table; excluded from p-values per variable): cns_grp=14; wbc_cat=7; sex=1.
1 n (%)
2 Pearson’s Chi-squared test