Mouse Brain Aging and Lipid Metabolism

Qiu lab @UA College of Medicine - Phoenix.
Visium HD analysis on collaborative projects, with Daping FAN

Mouse Brain Tissue Arrays including Prefrontal Cortex, and Hippocampus

Sectioned hippocampus tissue, from different groups, and cell clusters
Cell segmented output from Space Ranger V4.0.1

Cell segmentation is based on H&E staining and nucleus expansion`

Visium HD analysis of the mouse hippocampus tissue, microdissected for sectioning into 15um thickness. Enlarged view.

Different view of another three sections



Mouse hippocampus enlarged view, clusters are well separated.

mouse hippocampus show region specific gene expressions!!

Mouse Prefrontal Cortex Tissue Arrayed on Visium HD Chip

Mouse PFC section, enlarged view showing clusters

Mouse PFC section, another sample on the same chip