Presence of Central Nonenhancement Correlates With Tumor Exophyticity

Author

Lu Mao

Published

December 3, 2025

There are a total of 119 patients with both exophyticity and CNE (0=No, 1=Yes) data available for analysis.

CNE vs Exophyticity

CNE distribution within each exophytic category is summarized in Table 1.

Table 1: CNE distribution by exophytic category.
Exophyticity Category N CNE Yes CNE No CNE (%)
0% (Endophytic) 4 1 3 25.0
<50% Exophytic 26 14 12 53.8
>50% Exophytic 89 67 22 75.3

A logistic regression model was fitted to estimate the effect size of exophyticity on the odds of having CNE. Table 2 summarizes the results.

Table 2: Logistic regression effect size estimation for CNE by exophyticity.
Effect OR 95% CI p-value
Per-category increase in exophyticity 2.76 (1.34, 5.97) 0.0073