A Statistical and Epidemiological Analysis




Natalie Olenkovsky



Department of Mathematical Sciences
Kean University



Date: November 19, 2025


Welcome

This website presents a complete statistical analysis of blood lead exposure and its relationship to systolic blood pressure (SBP) among U.S. adults using NHANES 2021–2023 data.

The project is divided into clear, organized sections and each page walks through a different stage of the analysis pipeline, from data cleaning to modeling and interpretation.


Key Questions

  • How is blood lead distributed in the U.S. population?
  • Is higher blood lead associated with higher systolic blood pressure?
  • Do factors like race/ethnicity, smoking status, BMI, or income modify this association?
  • How does NHANES sampling affect interpretation?

About NHANES

The National Health and Nutrition Examination Survey (NHANES) is a nationally representative study conducted by the CDC.
It collects:

  • Laboratory biomonitoring (including blood lead)
  • Clinical measurements (including blood pressure)
  • Anthropometrics (BMI)
  • Demographics & socioeconomic data
  • Questionnaire-based health behaviors

NHANES is one of the most comprehensive datasets available for studying environmental exposures and health.


Website Sections

Below is a quick overview of what each page contains.


πŸ“ Data Setup

Importing and cleaning the NHANES datasets (demographics, lab values, blood pressure, BMI, smoking).


πŸ“ Methods

Variable definitions, transformations (log-lead), statistical decisions, and modeling strategy.


πŸ” Exploratory Data Analysis

Histograms, scatterplots, outlier analysis, and stratified comparisons (e.g., by race).


πŸ“ˆ Modeling

Regression models evaluating lead β†’ blood pressure relationships.


🧠 Discussion

Interpretation of findings, limitations, and public health relevance.


πŸ“š References

Citations for NHANES documentation, CDC methods, and relevant lead–BP literature.


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