subgroups
#1-KM
#1-KM all
#1-KM final_master_sarcopenia
#1-KM final_master_no_sarcopenia
test interaction cox death 365 sarcopenia all
:sarcopenia*baseline_cys_c_egfr
| Characteristic |
N |
HR |
95% CI |
p-value |
| sarcopenia |
458 |
|
|
|
| 0 |
|
— |
— |
|
| 1 |
|
2.52 |
0.52, 12.3 |
0.252 |
| baseline_cys_c_egfr |
458 |
0.96 |
0.94, 0.98 |
<0.001 |
| age |
458 |
1.01 |
0.98, 1.03 |
0.539 |
| sex |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.72 |
0.45, 1.15 |
0.172 |
| cancer_stage |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
4.71 |
1.89, 11.8 |
<0.001 |
| ecog_score |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
1.51 |
0.89, 2.56 |
0.123 |
| 3 |
|
2.26 |
1.08, 4.75 |
0.031 |
| 4 |
|
2.00 |
0.55, 7.23 |
0.289 |
| baseline_cre_egfr |
458 |
1.04 |
1.02, 1.06 |
<0.001 |
| sarcopenia * baseline_cys_c_egfr |
458 |
|
|
|
| 1 * baseline_cys_c_egfr |
|
0.99 |
0.97, 1.02 |
0.553 |
test interaction cox death 365 sarcopenia all
:z_score*baseline_cys_c_egfr
| Characteristic |
N |
HR |
95% CI |
p-value |
| z_score |
458 |
1.22 |
0.70, 2.11 |
0.481 |
| baseline_cys_c_egfr |
458 |
0.96 |
0.94, 0.97 |
<0.001 |
| age |
458 |
1.01 |
0.99, 1.04 |
0.408 |
| sex |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.59 |
0.37, 0.93 |
0.025 |
| cancer_stage |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
4.51 |
1.81, 11.2 |
0.001 |
| ecog_score |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
1.56 |
0.93, 2.63 |
0.094 |
| 3 |
|
2.28 |
1.08, 4.78 |
0.030 |
| 4 |
|
2.57 |
0.73, 9.06 |
0.142 |
| baseline_cre_egfr |
458 |
1.04 |
1.02, 1.06 |
<0.001 |
| z_score * baseline_cys_c_egfr |
458 |
1.00 |
0.99, 1.01 |
0.522 |
test interaction cox death 365 sarcopenia all
:z_score*baseline_cys_c_egfr_dose
| Characteristic |
N |
HR |
95% CI |
p-value |
| z_score |
458 |
1.04 |
0.80, 1.37 |
0.758 |
| baseline_cys_c_egfr_dose |
458 |
|
|
|
| >=60 |
|
— |
— |
|
| 45 - 59.99 |
|
2.33 |
1.16, 4.66 |
0.017 |
| <45 |
|
6.81 |
2.98, 15.6 |
<0.001 |
| age |
458 |
1.02 |
1.00, 1.04 |
0.114 |
| sex |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.56 |
0.35, 0.89 |
0.015 |
| cancer_stage |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
4.50 |
1.80, 11.3 |
0.001 |
| ecog_score |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
1.74 |
1.03, 2.93 |
0.037 |
| 3 |
|
3.06 |
1.45, 6.45 |
0.003 |
| 4 |
|
2.94 |
0.84, 10.3 |
0.091 |
| baseline_cre_egfr |
458 |
1.03 |
1.01, 1.05 |
<0.001 |
| z_score * baseline_cys_c_egfr_dose |
458 |
|
|
|
| z_score * 45 - 59.99 |
|
0.86 |
0.54, 1.39 |
0.551 |
| z_score * <45 |
|
1.15 |
0.72, 1.83 |
0.557 |
test interaction cox death 365 sarcopenia all
:sarcopenia*cr_cys_7
| Characteristic |
N |
HR |
95% CI |
p-value |
| sarcopenia |
458 |
|
|
|
| 0 |
|
— |
— |
|
| 1 |
|
1.84 |
0.93, 3.64 |
0.082 |
| cr_cys_7 |
458 |
3.18 |
1.80, 5.62 |
<0.001 |
| age |
458 |
1.01 |
0.98, 1.03 |
0.551 |
| sex |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.50 |
0.30, 0.81 |
0.005 |
| cancer_stage |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
5.08 |
2.04, 12.6 |
<0.001 |
| ecog_score |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
1.45 |
0.85, 2.48 |
0.178 |
| 3 |
|
2.32 |
1.09, 4.96 |
0.030 |
| 4 |
|
2.39 |
0.68, 8.44 |
0.176 |
| baseline_cre_egfr |
458 |
1.00 |
0.99, 1.01 |
0.845 |
| sarcopenia * cr_cys_7 |
458 |
|
|
|
| 1 * cr_cys_7 |
|
0.65 |
0.26, 1.64 |
0.363 |
test interaction cox death 365 sarcopenia all :z_score*cr_cys_7
| Characteristic |
N |
HR |
95% CI |
p-value |
| z_score |
458 |
0.81 |
0.60, 1.09 |
0.159 |
| cr_cys_7 |
458 |
3.98 |
2.28, 6.95 |
<0.001 |
| age |
458 |
1.01 |
0.99, 1.04 |
0.358 |
| sex |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.43 |
0.27, 0.69 |
<0.001 |
| cancer_stage |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
5.03 |
2.03, 12.5 |
<0.001 |
| ecog_score |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
1.55 |
0.91, 2.65 |
0.106 |
| 3 |
|
2.39 |
1.12, 5.09 |
0.024 |
| 4 |
|
2.68 |
0.78, 9.27 |
0.119 |
| baseline_cre_egfr |
458 |
1.00 |
0.99, 1.01 |
0.951 |
| z_score * cr_cys_7 |
458 |
1.57 |
1.07, 2.30 |
0.021 |
test interaction cox death 365 sarcopenia all :z_score*cr_cys
| Characteristic |
N |
HR |
95% CI |
p-value |
| z_score |
458 |
2.35 |
0.96, 5.74 |
0.061 |
| cr_cys |
458 |
0.01 |
0.00, 0.06 |
<0.001 |
| age |
458 |
1.01 |
0.98, 1.03 |
0.646 |
| sex |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.37 |
0.23, 0.60 |
<0.001 |
| cancer_stage |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
4.42 |
1.78, 11.0 |
0.001 |
| ecog_score |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
1.49 |
0.88, 2.52 |
0.142 |
| 3 |
|
2.26 |
1.07, 4.74 |
0.032 |
| 4 |
|
2.13 |
0.59, 7.72 |
0.248 |
| baseline_cre_egfr |
458 |
1.00 |
0.98, 1.01 |
0.598 |
| z_score * cr_cys |
458 |
0.31 |
0.09, 1.08 |
0.065 |
cox death 365 sarcopenia all
| Characteristic |
N |
HR |
95% CI |
p-value |
| sarcopenia |
458 |
|
|
|
| 0 |
|
— |
— |
|
| 1 |
|
1.57 |
0.95, 2.61 |
0.081 |
| age |
458 |
1.02 |
0.99, 1.04 |
0.132 |
| sex |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.65 |
0.41, 1.03 |
0.066 |
| cancer_stage |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
5.54 |
2.23, 13.8 |
<0.001 |
| ecog_score |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
1.81 |
1.07, 3.05 |
0.027 |
| 3 |
|
3.50 |
1.68, 7.26 |
<0.001 |
| 4 |
|
3.76 |
1.07, 13.2 |
0.038 |
| baseline_cre_egfr |
458 |
1.01 |
0.99, 1.02 |
0.442 |
cox death 365 z_score_sarcopenia all
| Characteristic |
N |
HR |
95% CI |
p-value |
| z_score_sarcopenia |
458 |
|
|
|
| 0 |
|
— |
— |
|
| 1 |
|
1.12 |
0.70, 1.79 |
0.627 |
| age |
458 |
1.02 |
1.00, 1.05 |
0.072 |
| sex |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.58 |
0.37, 0.93 |
0.024 |
| cancer_stage |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
5.57 |
2.24, 13.8 |
<0.001 |
| ecog_score |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
1.87 |
1.11, 3.17 |
0.019 |
| 3 |
|
3.59 |
1.72, 7.49 |
<0.001 |
| 4 |
|
4.52 |
1.32, 15.5 |
0.017 |
| baseline_cre_egfr |
458 |
1.01 |
0.99, 1.02 |
0.444 |
cox death 365 cr_cys_7 all
| Characteristic |
N |
HR |
95% CI |
p-value |
| cr_cys_7 |
458 |
2.82 |
1.77, 4.50 |
<0.001 |
| age |
458 |
1.01 |
0.99, 1.04 |
0.360 |
| sex |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.45 |
0.29, 0.70 |
<0.001 |
| cancer_stage |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
5.13 |
2.06, 12.7 |
<0.001 |
| ecog_score |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
1.49 |
0.87, 2.54 |
0.146 |
| 3 |
|
2.35 |
1.10, 5.04 |
0.028 |
| 4 |
|
2.86 |
0.82, 9.93 |
0.098 |
| baseline_cre_egfr |
458 |
1.00 |
0.99, 1.01 |
0.838 |
cox death 365 group all
| Characteristic |
N |
HR |
95% CI |
p-value |
| group |
458 |
|
|
|
| none |
|
— |
— |
|
| no sarcopenia & cr_cys_7 |
|
3.18 |
1.80, 5.62 |
<0.001 |
| sarcopenia & cr_cys_7 |
|
3.81 |
1.88, 7.70 |
<0.001 |
| sarcopenia & no cr_cys_7 |
|
1.84 |
0.93, 3.64 |
0.082 |
| age |
458 |
1.01 |
0.98, 1.03 |
0.551 |
| sex |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.50 |
0.30, 0.81 |
0.005 |
| cancer_stage |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
5.08 |
2.04, 12.6 |
<0.001 |
| ecog_score |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
1.45 |
0.85, 2.48 |
0.178 |
| 3 |
|
2.32 |
1.09, 4.96 |
0.030 |
| 4 |
|
2.39 |
0.68, 8.44 |
0.176 |
| baseline_cre_egfr |
458 |
1.00 |
0.99, 1.01 |
0.845 |
cox death group_60 all
| Characteristic |
N |
HR |
95% CI |
p-value |
| group_60 |
458 |
|
|
|
| no sarcopenia & >=60 |
|
— |
— |
|
| no sarcopenia & <60 |
|
2.68 |
1.46, 4.91 |
0.001 |
| sarcopenia & <60 |
|
5.32 |
2.50, 11.3 |
<0.001 |
| sarcopenia & >=60 |
|
1.32 |
0.60, 2.90 |
0.491 |
| age |
458 |
1.02 |
0.99, 1.04 |
0.217 |
| sex |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.73 |
0.45, 1.17 |
0.192 |
| cancer_stage |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
4.85 |
1.94, 12.1 |
<0.001 |
| ecog_score |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
1.61 |
0.95, 2.74 |
0.076 |
| 3 |
|
3.17 |
1.52, 6.60 |
0.002 |
| 4 |
|
2.63 |
0.73, 9.38 |
0.137 |
| baseline_cre_egfr |
458 |
1.02 |
1.01, 1.04 |
0.007 |
cox death baseline_cys_c_egfr_dose all
| Characteristic |
N |
HR |
95% CI |
p-value |
| baseline_cys_c_egfr_dose |
458 |
|
|
|
| >=60 |
|
— |
— |
|
| 45 - 59.99 |
|
2.61 |
1.50, 4.55 |
<0.001 |
| <45 |
|
6.00 |
2.81, 12.8 |
<0.001 |
| age |
458 |
1.02 |
1.00, 1.05 |
0.103 |
| sex |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.57 |
0.37, 0.88 |
0.011 |
| cancer_stage |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
4.65 |
1.87, 11.6 |
<0.001 |
| ecog_score |
458 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
1.72 |
1.02, 2.90 |
0.041 |
| 3 |
|
2.96 |
1.40, 6.22 |
0.004 |
| 4 |
|
2.97 |
0.85, 10.3 |
0.087 |
| baseline_cre_egfr |
458 |
1.03 |
1.01, 1.05 |
<0.001 |
cox death 365 sarcopenia final_master_sarcopenia
## Warning in coxph.fit(X, Y, istrat, offset, init, control, weights = weights, :
## Loglik converged before variable 7 ; coefficient may be infinite.
| Characteristic |
N |
HR |
95% CI |
p-value |
| sarcopenia |
87 |
|
|
|
| 0 |
|
— |
— |
|
| 1 |
|
|
|
|
| age |
87 |
1.03 |
0.98, 1.08 |
0.284 |
| sex |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.51 |
0.17, 1.52 |
0.225 |
| cancer_stage |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
4.23 |
0.94, 19.1 |
0.060 |
| ecog_score |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
1.28 |
0.52, 3.17 |
0.595 |
| 3 |
|
1.87 |
0.47, 7.54 |
0.377 |
| 4 |
|
0.00 |
0.00, Inf |
0.998 |
| baseline_cre_egfr |
87 |
1.00 |
0.98, 1.03 |
0.879 |
cox death 365 z_score_sarcopenia final_master_sarcopenia
## Warning in coxph.fit(X, Y, istrat, offset, init, control, weights = weights, :
## Loglik converged before variable 7 ; coefficient may be infinite.
| Characteristic |
N |
HR |
95% CI |
p-value |
| z_score_sarcopenia |
87 |
|
|
|
| 0 |
|
— |
— |
|
| 1 |
|
0.91 |
0.20, 4.09 |
0.900 |
| age |
87 |
1.03 |
0.98, 1.08 |
0.287 |
| sex |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.51 |
0.17, 1.56 |
0.240 |
| cancer_stage |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
4.20 |
0.92, 19.1 |
0.063 |
| ecog_score |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
1.27 |
0.51, 3.17 |
0.604 |
| 3 |
|
1.88 |
0.47, 7.61 |
0.374 |
| 4 |
|
0.00 |
0.00, Inf |
0.998 |
| baseline_cre_egfr |
87 |
1.00 |
0.98, 1.03 |
0.863 |
cox death 365 cr_cys_7 final_master_sarcopenia
## Warning in coxph.fit(X, Y, istrat, offset, init, control, weights = weights, :
## Loglik converged before variable 7 ; coefficient may be infinite.
| Characteristic |
N |
HR |
95% CI |
p-value |
| cr_cys_7 |
87 |
2.50 |
1.11, 5.63 |
0.027 |
| age |
87 |
1.03 |
0.98, 1.08 |
0.286 |
| sex |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.47 |
0.15, 1.46 |
0.194 |
| cancer_stage |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
4.45 |
1.00, 19.9 |
0.051 |
| ecog_score |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.94 |
0.36, 2.47 |
0.904 |
| 3 |
|
1.13 |
0.25, 5.08 |
0.870 |
| 4 |
|
0.00 |
0.00, Inf |
0.998 |
| baseline_cre_egfr |
87 |
1.00 |
0.98, 1.02 |
0.892 |
cox death 365 group final_master_sarcopenia
## Warning in coxph.fit(X, Y, istrat, offset, init, control, weights = weights, :
## Loglik converged before variable 9 ; coefficient may be infinite.
| Characteristic |
N |
HR |
95% CI |
p-value |
| group |
87 |
|
|
|
| none |
|
— |
— |
|
| no sarcopenia & cr_cys_7 |
|
|
|
|
| sarcopenia & cr_cys_7 |
|
2.50 |
1.11, 5.63 |
0.027 |
| sarcopenia & no cr_cys_7 |
|
|
|
|
| age |
87 |
1.03 |
0.98, 1.08 |
0.286 |
| sex |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.47 |
0.15, 1.46 |
0.194 |
| cancer_stage |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
4.45 |
1.00, 19.9 |
0.051 |
| ecog_score |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.94 |
0.36, 2.47 |
0.904 |
| 3 |
|
1.13 |
0.25, 5.08 |
0.870 |
| 4 |
|
0.00 |
0.00, Inf |
0.998 |
| baseline_cre_egfr |
87 |
1.00 |
0.98, 1.02 |
0.892 |
cox death group_60 final_master_sarcopenia
## Warning in coxph.fit(X, Y, istrat, offset, init, control, weights = weights, :
## Loglik converged before variable 9 ; coefficient may be infinite.
| Characteristic |
N |
HR |
95% CI |
p-value |
| group_60 |
87 |
|
|
|
| no sarcopenia & >=60 |
|
— |
— |
|
| no sarcopenia & <60 |
|
|
|
|
| sarcopenia & <60 |
|
5.67 |
1.95, 16.5 |
0.001 |
| sarcopenia & >=60 |
|
|
|
|
| age |
87 |
1.02 |
0.97, 1.08 |
0.385 |
| sex |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.89 |
0.28, 2.81 |
0.837 |
| cancer_stage |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
4.28 |
0.94, 19.5 |
0.060 |
| ecog_score |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.88 |
0.34, 2.31 |
0.801 |
| 3 |
|
1.76 |
0.43, 7.14 |
0.431 |
| 4 |
|
0.00 |
0.00, Inf |
0.998 |
| baseline_cre_egfr |
87 |
1.03 |
1.00, 1.07 |
0.038 |
cox death baseline_cys_c_egfr_dose final_master_sarcopenia
## Warning in coxph.fit(X, Y, istrat, offset, init, control, weights = weights, :
## Loglik converged before variable 8 ; coefficient may be infinite.
| Characteristic |
N |
HR |
95% CI |
p-value |
| baseline_cys_c_egfr_dose |
87 |
|
|
|
| >=60 |
|
— |
— |
|
| 45 - 59.99 |
|
5.91 |
1.91, 18.3 |
0.002 |
| <45 |
|
28.9 |
4.99, 167 |
<0.001 |
| age |
87 |
1.05 |
0.99, 1.11 |
0.094 |
| sex |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.92 |
0.28, 3.05 |
0.898 |
| cancer_stage |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
5.71 |
1.15, 28.4 |
0.033 |
| ecog_score |
87 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.69 |
0.25, 1.88 |
0.468 |
| 3 |
|
1.41 |
0.33, 5.99 |
0.642 |
| 4 |
|
0.00 |
0.00, Inf |
0.997 |
| baseline_cre_egfr |
87 |
1.07 |
1.02, 1.12 |
0.004 |
cox death 365 sarcopenia final_master_no_sarcopenia
| Characteristic |
N |
HR |
95% CI |
p-value |
| sarcopenia |
371 |
|
|
|
| 0 |
|
— |
— |
|
| 1 |
|
|
|
|
| age |
371 |
1.01 |
0.98, 1.04 |
0.354 |
| sex |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.58 |
0.34, 1.00 |
0.052 |
| cancer_stage |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
6.60 |
2.05, 21.3 |
0.002 |
| ecog_score |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
2.19 |
1.15, 4.17 |
0.018 |
| 3 |
|
4.61 |
1.92, 11.1 |
<0.001 |
| 4 |
|
25.6 |
6.72, 97.2 |
<0.001 |
| baseline_cre_egfr |
371 |
1.00 |
0.99, 1.02 |
0.894 |
cox death 365 z_score_sarcopenia final_master_no_sarcopenia
| Characteristic |
N |
HR |
95% CI |
p-value |
| z_score_sarcopenia |
371 |
|
|
|
| 0 |
|
— |
— |
|
| 1 |
|
0.86 |
0.43, 1.72 |
0.673 |
| age |
371 |
1.01 |
0.98, 1.04 |
0.358 |
| sex |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.57 |
0.32, 0.99 |
0.047 |
| cancer_stage |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
6.64 |
2.06, 21.4 |
0.002 |
| ecog_score |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
2.14 |
1.11, 4.11 |
0.023 |
| 3 |
|
4.50 |
1.85, 10.9 |
<0.001 |
| 4 |
|
24.8 |
6.47, 94.8 |
<0.001 |
| baseline_cre_egfr |
371 |
1.00 |
0.98, 1.02 |
0.908 |
cox death 365 cr_cys_7 final_master_no_sarcopenia
| Characteristic |
N |
HR |
95% CI |
p-value |
| cr_cys_7 |
371 |
3.05 |
1.68, 5.53 |
<0.001 |
| age |
371 |
1.00 |
0.97, 1.03 |
0.954 |
| sex |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.44 |
0.25, 0.77 |
0.004 |
| cancer_stage |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
5.90 |
1.83, 19.0 |
0.003 |
| ecog_score |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
1.81 |
0.94, 3.50 |
0.076 |
| 3 |
|
3.29 |
1.34, 8.10 |
0.009 |
| 4 |
|
14.0 |
3.61, 54.5 |
<0.001 |
| baseline_cre_egfr |
371 |
1.0 |
0.98, 1.01 |
0.491 |
cox death 365 group final_master_no_sarcopenia
| Characteristic |
N |
HR |
95% CI |
p-value |
| group |
371 |
|
|
|
| none |
|
— |
— |
|
| no sarcopenia & cr_cys_7 |
|
3.05 |
1.68, 5.53 |
<0.001 |
| sarcopenia & cr_cys_7 |
|
|
|
|
| sarcopenia & no cr_cys_7 |
|
|
|
|
| age |
371 |
1.00 |
0.97, 1.03 |
0.954 |
| sex |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.44 |
0.25, 0.77 |
0.004 |
| cancer_stage |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
5.90 |
1.83, 19.0 |
0.003 |
| ecog_score |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
1.81 |
0.94, 3.50 |
0.076 |
| 3 |
|
3.29 |
1.34, 8.10 |
0.009 |
| 4 |
|
14.0 |
3.61, 54.5 |
<0.001 |
| baseline_cre_egfr |
371 |
1.0 |
0.98, 1.01 |
0.491 |
cox death group_60 final_master_no_sarcopenia
| Characteristic |
N |
HR |
95% CI |
p-value |
| group_60 |
371 |
|
|
|
| no sarcopenia & >=60 |
|
— |
— |
|
| no sarcopenia & <60 |
|
2.35 |
1.24, 4.45 |
0.009 |
| sarcopenia & <60 |
|
|
|
|
| sarcopenia & >=60 |
|
|
|
|
| age |
371 |
1.01 |
0.98, 1.04 |
0.582 |
| sex |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.62 |
0.36, 1.06 |
0.081 |
| cancer_stage |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
5.71 |
1.76, 18.5 |
0.004 |
| ecog_score |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
2.08 |
1.09, 3.97 |
0.026 |
| 3 |
|
4.26 |
1.76, 10.3 |
0.001 |
| 4 |
|
21.7 |
5.65, 83.4 |
<0.001 |
| baseline_cre_egfr |
371 |
1.01 |
0.99, 1.03 |
0.180 |
cox death baseline_cys_c_egfr_dose final_master_no_sarcopenia
| Characteristic |
N |
HR |
95% CI |
p-value |
| baseline_cys_c_egfr_dose |
371 |
|
|
|
| >=60 |
|
— |
— |
|
| 45 - 59.99 |
|
2.12 |
1.08, 4.16 |
0.029 |
| <45 |
|
4.01 |
1.57, 10.3 |
0.004 |
| age |
371 |
1.01 |
0.98, 1.04 |
0.543 |
| sex |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
0.59 |
0.34, 1.02 |
0.061 |
| cancer_stage |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
5.62 |
1.74, 18.2 |
0.004 |
| ecog_score |
371 |
|
|
|
| 1 |
|
— |
— |
|
| 2 |
|
2.11 |
1.11, 4.03 |
0.023 |
| 3 |
|
4.08 |
1.68, 9.91 |
0.002 |
| 4 |
|
17.0 |
4.21, 68.7 |
<0.001 |
| baseline_cre_egfr |
371 |
1.02 |
1.00, 1.04 |
0.065 |