Table 4. Combined effect of Weekend Warrior and Biological age With the Risk of HF
Inactive
Active Weekend Warrior
Active Regular
HR (95%CI) P HR (95%CI) P HR (95%CI) P
PhenoAge
First Quartile Ref. Ref. Ref.
Second Quartile 0.65(0.49 - 0.87) 0.004 0.61(0.48 - 0.77) <0.001 0.72(0.6 - 0.85) <0.001
Third Quartile 0.89(0.64 - 1.25) 0.509 0.7(0.52 - 0.94) 0.018 0.73(0.58 - 0.91) 0.005
KDM-BA
First Quartile Ref. Ref. Ref.
Second Quartile 0.71(0.54 - 0.94) 0.016 0.61(0.48 - 0.78) <0.001 0.7(0.58 - 0.83) <0.001
Third Quartile 0.87(0.63 - 1.2) 0.395 0.73(0.54 - 0.98) 0.035 0.72(0.57 - 0.91) 0.006
HF: Heart Failure.
The effects are presented as hazard ratios with 95% confidence interval, with the participants who were physically inactive as the reference group.
Model was adjusted for age, sex, ethnic, education level, employment status, smoking, drinking, Townsend deprivation index, BMI, income.
Quartiles are based on biological age measures (KDM-BA and PhenoAge).