Table 2 Changes in the Global Burden of All causes Deaths Associated with Metabolic syndrome from 1990 to 2021
Numbers with uncertainty interval (95% UI)
Age-standardized rate per 100 000 population (95% UI)
location
1990
2021
1990
2021
EAPC, 95% CI(Deaths) EAPC, 95% CI(DALYS)
Numbers of Death (95% UI) Numbers of DALYs (95% UI) Numbers of Death (95% UI) Numbers of DALYs (95% UI) Death rate (95% UI) DALY rate (95% UI) Death rate (95% UI) DALY rate (95% UI)
Global 10278657.86 (9232874.48, 11289768.42) 262046321.41 (232254254.76, 292037946.2) 18562545.86 (16337592.8, 20590813.15) 476078739.99 (412470868.22, 541393380.18) 299.44 (268.23, 329.29) 6737.88 (5968.9, 7496.49) 224.03 (197.01, 248.57) 5582.42 (4839.55, 6345.44) -1.02 (-1.07 to -0.97) -0.71 (-0.76 to -0.67)
Southeast Asia 714711.5 (631474.61, 796191.37) 20628171.17 (18472572.79, 22960692.39) 1777571.55 (1577126.48, 1994550.31) 49818062.16 (44276342.49, 56268251.12) 327.28 (286.75, 365.99) 7847.79 (6985.82, 8770.98) 309.76 (275.81, 345.29) 7604.92 (6772.33, 8561.56) -0.16 (-0.26 to -0.05) -0.1 (-0.17 to -0.04)
East Asia 1861596.18 (1558628.92, 2159570.41) 50132496.91 (42440557.33, 58125794.17) 4421971.25 (3633556.64, 5299081.42) 103402729.53 (84314210.87, 123161851.31) 291.35 (245.46, 336.16) 6173.61 (5265.91, 7156.58) 230.8 (190.26, 275.74) 5006.71 (4092.54, 5958) -0.63 (-0.82 to -0.44) -0.62 (-0.75 to -0.48)
Oceania 10320.05 (8549.27, 12448.25) 339108.94 (279613.32, 412526.46) 26057.45 (21646.22, 30848.73) 899246.78 (750974.59, 1060548.55) 416.24 (350.95, 491.17) 10616.22 (8897.61, 12780.59) 399.39 (334.81, 466.39) 10831.07 (9095.59, 12676.33) -0.16 (-0.21 to -0.11) 0.05 (-0.00 to 0.11)
Central Asia 171825.19 (153159.25, 187449.25) 4267118.89 (3772456.39, 4720582.08) 254364.2 (225030.22, 284861.35) 6645869.43 (5746722.5, 7607495.28) 409.43 (365.01, 446.8) 9216.15 (8168.36, 10168.85) 373.96 (331.31, 420.25) 8393.03 (7290.93, 9549.95) -0.62 (-0.91 to -0.33) -0.71 (-1.02 to -0.40)
Central Europe 617557.4 (557115.27, 667999.9) 13987543.43 (12423366.11, 15511390.39) 621566.5 (544504.56, 703140.77) 12891457.41 (10929209.76, 14997596.74) 459.45 (413.43, 497.56) 9729.17 (8644.66, 10786.9) 262.33 (230, 296.92) 5893.55 (4957.57, 6888.72) -2.06 (-2.15 to -1.96) -1.87 (-1.95 to -1.78)
High-income Asia Pacific 321225.76 (282888.2, 354654.67) 7864656.49 (6854966.4, 8899086.76) 448633.95 (359568.33, 533612.65) 10456204.16 (8490187.34, 12774147.29) 180.72 (158.65, 200.08) 4056.54 (3545.62, 4588.15) 72.62 (59.15, 85.89) 2358.28 (1902.81, 2895.23) -3.08 (-3.23 to -2.93) -1.91 (-2.04 to -1.79)
Eastern Europe 1125944.26 (1009400.29, 1225641.91) 25142862.25 (22256108.2, 27822788.12) 1240445.75 (1089773.78, 1409748.57) 26330863.54 (22665766.7, 30307662.46) 455.42 (405.51, 497.37) 9430.56 (8333.5, 10436.82) 347.62 (305.41, 395.02) 7639.61 (6551.85, 8799.42) -1.43 (-1.86 to -1.00) -1.29 (-1.74 to -0.85)
Western Europe 1464439.36 (1295730.95, 1619711.82) 29743001.41 (25687666.64, 33843678.59) 1276578.77 (1036186.79, 1499878.92) 26389678.2 (20802217.74, 32421005.56) 245.69 (216.72, 272.01) 5190.79 (4464.86, 5941.52) 108.12 (87.76, 127.57) 2828.12 (2190.36, 3518.12) -2.74 (-2.85 to -2.64) -2.06 (-2.18 to -1.95)
Australasia 53940.44 (47558.36, 60047.88) 1198415.51 (1013831.15, 1389540.44) 59881.45 (48009.57, 70872.29) 1443013.47 (1068942.71, 1826747.9) 239.25 (210.37, 266.77) 5203.43 (4400.58, 6036.64) 97.61 (78.19, 115.64) 2780.73 (2020.98, 3586.02) -3.02 (-3.14 to -2.89) -2.1 (-2.25 to -1.96)
Southern Latin America 113809.58 (99510.04, 126412.79) 2736617.94 (2313523.84, 3128968.05) 135360.67 (115415.94, 153738.92) 3448374.95 (2779485.53, 4139864.52) 267.5 (234.23, 297.02) 6039.93 (5097.85, 6905.02) 149.51 (127.36, 169.82) 4003.76 (3215.61, 4820.34) -1.58 (-1.66 to -1.51) -1.17 (-1.22 to -1.11)
High-income North America 844199.07 (736251.1, 942868.83) 18987823.46 (15931138.44, 22198128.16) 1084570.56 (892501.97, 1255154.01) 27993258.65 (22357142.76, 33817193.06) 232.96 (203.26, 260.29) 5492.63 (4598.92, 6433.96) 154.26 (126.89, 178.09) 4531.24 (3579.13, 5516.8) -1.6 (-1.75 to -1.45) -0.77 (-0.89 to -0.65)
Caribbean 75517.75 (67902.7, 82614.14) 1952192.13 (1736689.44, 2155851.3) 131604.5 (112581.64, 151927.04) 3559425.02 (3053051.09, 4134601.32) 314.39 (282.5, 344.31) 7467.26 (6637.47, 8233.03) 241.58 (207.06, 279) 6653.29 (5706.14, 7729.69) -0.8 (-0.93 to -0.67) -0.32 (-0.44 to -0.20)
Andean Latin America 33366.71 (29106.56, 37794.69) 960831.15 (818552.37, 1109883.46) 89264.25 (74024.95, 108621.13) 2465285.04 (2039885.42, 2986685.95) 176.13 (153.34, 198.81) 4380.85 (3735.39, 5058.78) 156.48 (130.13, 190.15) 4123.16 (3420, 4987.54) -0.38 (-0.48 to -0.28) -0.22 (-0.32 to -0.13)
Central Latin America 190340.99 (174559.49, 204870.72) 5614542.43 (4986266.93, 6285835.87) 556109.54 (491931.89, 628340.87) 15807814.19 (13771088.77, 18345742.39) 260.98 (238.28, 280.9) 6450.85 (5739.39, 7207.73) 230.37 (203.96, 260.06) 6250.46 (5449.23, 7244.07) -0.46 (-0.56 to -0.35) -0.18 (-0.27 to -0.10)
Tropical Latin America 235427.21 (212577.54, 254633.35) 6823441.17 (6077434.36, 7608580.49) 430336.88 (375880.81, 482887.3) 12316097.32 (10351560.03, 14331480.23) 296.15 (266.91, 322.12) 7262.93 (6474.25, 8085.61) 172.42 (150.43, 193.75) 4793.46 (4030, 5585.67) -1.63 (-1.69 to -1.58) -1.33 (-1.38 to -1.29)
North Africa and Middle East 632389.58 (569868.73, 694170.38) 17149982.19 (15238241.07, 19161905.35) 1389074.37 (1217195.42, 1574441.21) 38992268.17 (33140368.46, 45193752.17) 460.52 (412.9, 505.43) 10159.07 (9049.31, 11315.99) 369.46 (324.5, 415.6) 8571.47 (7349.2, 9841.24) -0.69 (-0.76 to -0.61) -0.56 (-0.62 to -0.50)
South Asia 1242108.64 (1084227.42, 1384444.64) 37989064.73 (33204315.33, 42520852.18) 3401327.49 (3016017.31, 3750037.88) 97140152.86 (86889887.58, 108070710.88) 251.84 (218.23, 282.68) 6326.97 (5492.3, 7122.56) 260.81 (232.58, 288.09) 6516.42 (5828.61, 7257.18) 0.15 (0.04 to 0.26) 0.09 (0.02 to 0.17)
Central Sub-Saharan Africa 74461.96 (62160.58, 86616.28) 2224448.63 (1863668.91, 2589660.99) 164890.85 (132994.79, 199553.39) 5050531.18 (4091572.13, 6138120.11) 423.78 (359.56, 487.94) 9675.39 (8155.79, 11160.24) 392.34 (318.87, 472.75) 8977.75 (7310.97, 10749.84) -0.37 (-0.41 to -0.33) -0.36 (-0.40 to -0.32)
Southern Sub-Saharan Africa 62368.01 (55922.15, 69230.6) 1820671.13 (1607772.33, 2042158.04) 170297.82 (153634.68, 187786.65) 4764160.63 (4195819.15, 5346093.8) 261.07 (231.84, 291.7) 6443.62 (5709.17, 7243.26) 349.45 (315.9, 384.2) 8260.35 (7325.42, 9276.24) 1.09 (0.64 to 1.55) 0.96 (0.55 to 1.36)
Eastern Sub-Saharan Africa 202071.4 (180876.05, 224163.88) 6016866 (5399426.72, 6677132.02) 391386.72 (344950.83, 445424.86) 11656943.88 (10137025.13, 13360630.09) 323.38 (287.22, 359.05) 7518.56 (6742.33, 8369.01) 282.85 (250.09, 320.66) 6497.63 (5666.59, 7443.04) -0.58 (-0.64 to -0.53) -0.64 (-0.70 to -0.59)
Western Sub-Saharan Africa 231036.82 (200550.13, 261322.49) 6466465.47 (5713539.1, 7326171.73) 491251.33 (422607.29, 560682.57) 14607303.42 (12364732.25, 17061113.25) 312.77 (272.21, 354.3) 7105.49 (6227.26, 8062.79) 310.27 (270.22, 349.68) 7103.47 (6096.23, 8201.23) -0.02 (-0.11 to 0.07) -0.01 (-0.10 to 0.08)
Western Pacific Region 2421402.07 (2083925.83, 2761129.41) 64206999.73 (55216426.17, 73564097.54) 5442085.96 (4558418.69, 6386004.74) 129652184.84 (107115421.55, 151069561.28) 268.13 (232.4, 303.84) 5849.74 (5056.04, 6690.77) 200.2 (167.53, 234.25) 4715.78 (3900.61, 5488.03) -0.85 (-0.95 to -0.75) -0.65 (-0.73 to -0.58)