| Table 1. Baseline Characteristics | |||||
| Stratified by Heart Failure Status | |||||
| Variable | Level | Overall (n=72,468) |
Heart Failure Status
|
P-value | |
|---|---|---|---|---|---|
| No HF (n=71,092) | HF (n=1,376) | ||||
| Sample Size | |||||
| n | 72468 | 71092 | 1376 | ||
| Demographics | |||||
| age (mean (SD)) | 56.43 (7.83) | 56.31 (7.82) | 62.60 (5.87) | <0.001 | |
| Sex (%) | 0 | 40598 (56.0) | 40105 (56.4) | 493 (35.8) | <0.001 |
| Sex (%) | 1 | 31870 (44.0) | 30987 (43.6) | 883 (64.2) | |
| ethnic1 (%) | 1 | 70072 (96.7) | 68737 (96.7) | 1335 (97.0) | 0.543 |
| ethnic1 (%) | 2 | 2396 (3.3) | 2355 (3.3) | 41 (3.0) | |
| education1 (%) | 0 | 40940 (56.5) | 40000 (56.3) | 940 (68.3) | <0.001 |
| education1 (%) | 1 | 31528 (43.5) | 31092 (43.7) | 436 (31.7) | |
| employment (%) | 0 | 26793 (37.0) | 25935 (36.5) | 858 (62.4) | <0.001 |
| employment (%) | 1 | 45675 (63.0) | 45157 (63.5) | 518 (37.6) | |
| Lifestyle | |||||
| PA (%) | 0 | 12660 (17.5) | 12377 (17.4) | 283 (20.6) | NA |
| PA (%) | 1 | 30660 (42.3) | 30110 (42.4) | 550 (40.0) | |
| PA (%) | 2 | 29148 (40.2) | 28605 (40.2) | 543 (39.5) | |
| smoke0 (%) | 0 | 41560 (57.3) | 40946 (57.6) | 614 (44.6) | NA |
| smoke0 (%) | 1 | 25878 (35.7) | 25245 (35.5) | 633 (46.0) | |
| smoke0 (%) | 2 | 5030 (6.9) | 4901 (6.9) | 129 (9.4) | |
| drink0 (%) | 0 | 2019 (2.8) | 1971 (2.8) | 48 (3.5) | NA |
| drink0 (%) | 1 | 1913 (2.6) | 1848 (2.6) | 65 (4.7) | |
| drink0 (%) | 2 | 68536 (94.6) | 67273 (94.6) | 1263 (91.8) | |
| Clinical | |||||
| BMI (mean (SD)) | 26.66 (4.47) | 26.62 (4.44) | 28.86 (5.33) | <0.001 | |
| town_index (mean (SD)) | -1.73 (2.82) | -1.74 (2.81) | -1.45 (3.01) | <0.001 | |
| H_F (mean (SD)) | 0.02 (0.14) | 0.00 (0.00) | 1.00 (0.00) | <0.001 | |
| survival_H_F (mean (SD)) | 93.11 (12.94) | 93.78 (11.55) | 58.30 (26.44) | <0.001 | |
| Socioeconomic | |||||
| income (%) | 1 | 10826 (14.9) | 10456 (14.7) | 370 (26.9) | NA |
| income (%) | 2 | 17575 (24.3) | 17136 (24.1) | 439 (31.9) | |
| income (%) | 3 | 20824 (28.7) | 20489 (28.8) | 335 (24.3) | |
| income (%) | 4 | 17924 (24.7) | 17729 (24.9) | 195 (14.2) | |
| income (%) | 5 | 5319 (7.3) | 5282 (7.4) | 37 (2.7) | |
| Biological Aging | |||||
| kdm (mean (SD)) | 52.98 (8.89) | 52.82 (8.83) | 61.39 (7.90) | <0.001 | |
| kdm_res (mean (SD)) | -0.87 (4.54) | -0.91 (4.51) | 1.49 (5.62) | <0.001 | |
| phenoage (mean (SD)) | 46.69 (9.49) | 46.50 (9.41) | 56.11 (8.85) | <0.001 | |
| phenoage_res (mean (SD)) | -0.72 (5.00) | -0.78 (4.96) | 2.13 (6.09) | <0.001 | |