Breast Cancer Cell Lines
esther ye
July 25, 2025
About this activity
In this module, we will switch gears and work with data from experiments with human cancer cell lines from the Physical Sciences in Oncology (PS-ON) Cell Line Characterization Study.
Cancer cell lines are cancer cells that keep dividing and growing over time, under certain conditions in a laboratory. Cancer cell lines are used in research to study the biology of cancer and to test cancer treatments.
The PS-ON Study includes imaging- and microscopy-based measurements of physical properties of the cells, such as morphology (shape) and motility (movement). We will examine:
- the expression levels of genes, and
- how fast the cells move.
Preliminaries
Save this file with a different name and add your name as author.
We will load the imager library so we may look at some images in this activity.
Loading the data
PSON.RData contains gene expression and cell speed data from the Physical Sciences in Oncology project.
# The objects will also appear in our "Environment" tab.
load("/home/data/PSON.RData",verbose=TRUE) ## Loading objects:
## pson_expr_df
## cell_speeds_dfObjects were named to be be descriptive.
- “pson” stands for “Physical Sciences in Oncology”
- “expr” stands for “gene expression data”
- “df” stands for “data frame”
Compare the data frames
The Environment tab gives us basic information on the object that was loaded.
You can use some of the R functions we learned previously to remind us what is in the data frames we loaded.
The expression data frame
In `pson_expr_df, rows are named with the genes whose expression (mRNA) values were measured. Columns are named with identifiers for the experiments performed.
Gene names (“symbol”) are in the first column. We’ll create a numerical matrix of the mRNA levels and designate the gene symbols as names for the rows of the matrix.
# Remove the first column because it contains gene names
# and assign the result to a new object
# Replace N with the number needed to do this
# Remember, we want to remove something
pson_expr_mat <- as.matrix(pson_expr_df[, -1])
# Make the gene names into row names.
# Replace FEATURE with the correct column name
rownames(pson_expr_mat) <- pson_expr_df$symbol Use indexing to examine your new matrix pson_expr_mat. Does it match what you expect?
pson_expr_mat## mRNA_R17 mRNA_R21 mRNA_R20 mRNA_R19 mRNA_R18 mRNA_R16 mRNA_R15
## TSPAN6 33.56 45.10 39.42 35.61 32.10 39.49 29.90
## TNMD 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DPM1 169.46 129.88 132.06 113.73 123.37 136.29 137.98
## SCYL3 1.85 1.85 1.77 1.93 2.30 1.54 2.00
## C1orf112 5.73 11.85 10.16 9.28 10.01 8.93 7.47
## FGR 0.01 0.00 0.00 0.02 0.01 0.01 0.00
## CFH 0.01 0.01 0.00 0.00 0.04 0.01 0.01
## FUCA2 74.83 106.12 84.40 93.60 97.78 80.89 80.92
## GCLC 20.32 18.97 14.09 23.05 41.58 16.19 17.52
## NFYA 9.33 7.59 6.99 7.22 12.16 5.21 6.54
## STPG1 7.31 4.62 3.83 4.77 6.44 4.29 4.43
## NIPAL3 5.16 6.70 4.03 6.07 8.08 4.29 4.88
## LAS1L 60.45 79.98 61.51 72.49 79.89 60.03 61.80
## ENPP4 2.46 3.36 3.66 3.66 4.89 3.73 2.93
## SEMA3F 2.04 13.86 9.94 6.70 3.74 6.56 3.95
## CFTR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ANKIB1 5.10 6.80 6.03 5.90 6.34 5.03 4.74
## CYP51A1 29.44 35.23 22.17 35.19 52.60 27.85 30.32
## KRIT1 8.55 13.27 10.83 12.32 15.16 9.40 10.20
## RAD52 3.30 7.33 7.28 6.17 6.27 4.41 4.24
## BAD 38.40 62.70 62.31 63.08 57.11 65.70 53.07
## LAP3 51.10 39.85 34.46 42.25 59.96 38.35 43.07
## CD99 59.44 65.38 51.20 62.64 57.78 66.88 53.82
## HS3ST1 0.26 0.71 0.39 0.53 0.71 0.18 0.27
## AOC1 0.86 6.79 4.18 2.87 1.35 3.63 1.42
## WNT16 0.08 0.01 0.05 0.07 0.09 0.07 0.08
## HECW1 0.81 0.30 1.03 0.65 0.51 0.42 0.90
## MAD1L1 22.20 30.87 18.42 26.12 17.26 25.99 25.66
## LASP1 56.97 131.49 84.24 118.79 102.39 102.85 70.99
## SNX11 13.16 10.65 9.69 12.04 16.77 9.52 9.24
## TMEM176A 3.57 17.39 13.36 8.82 4.03 11.05 5.30
## M6PR 131.07 109.09 90.15 100.10 141.40 88.13 88.50
## KLHL13 0.01 0.03 0.01 0.00 0.01 0.00 0.01
## CYP26B1 0.02 0.05 0.10 0.03 0.06 0.03 0.01
## ICA1 12.58 17.83 14.13 14.06 10.24 13.94 15.39
## DBNDD1 0.93 3.25 2.57 2.48 1.30 2.76 1.71
## ALS2 10.28 5.65 4.42 6.12 8.93 4.57 5.67
## CASP10 0.23 0.07 0.13 0.10 0.08 0.18 0.21
## CFLAR 14.65 6.87 7.50 7.10 7.53 6.14 11.71
## TFPI 0.42 0.21 0.20 0.45 0.48 0.46 0.54
## NDUFAF7 7.30 8.03 7.47 8.32 8.79 7.12 5.99
## RBM5 15.64 19.95 20.32 21.15 24.95 15.63 13.95
## MTMR7 0.49 0.36 0.37 0.48 0.76 0.38 0.55
## SLC7A2 0.04 0.21 0.16 0.11 0.09 0.07 0.06
## ARF5 181.64 186.06 167.69 174.70 191.68 191.66 184.41
## SARM1 2.37 2.68 2.12 2.14 1.97 1.33 1.89
## POLDIP2 94.88 114.78 92.38 108.27 107.85 97.08 86.21
## PLXND1 4.14 16.91 9.97 11.60 7.44 12.74 7.91
## AK2 162.06 198.63 194.78 191.91 191.58 191.73 156.21
## CD38 0.01 0.00 0.00 0.00 0.00 0.00 0.00
## FKBP4 126.36 132.50 101.31 112.88 127.70 98.88 91.65
## KDM1A 49.29 78.81 56.11 57.72 60.19 57.73 51.39
## RBM6 19.93 22.43 21.27 20.02 25.52 18.30 21.47
## CAMKK1 6.10 7.52 6.32 8.64 11.63 5.98 7.46
## RECQL 43.85 50.41 40.05 47.02 52.54 36.12 39.06
## CCDC132 9.71 9.29 7.28 8.14 11.89 7.08 7.72
## HSPB6 0.04 0.00 0.00 0.09 0.08 0.08 0.11
## ARHGAP33 1.04 1.13 1.45 1.29 1.71 1.78 1.27
## NDUFAB1 253.05 219.84 281.67 237.48 249.03 256.73 272.65
## PDK4 0.12 0.14 0.04 0.12 0.13 0.11 0.14
## SLC22A16 0.00 0.00 0.00 0.03 0.02 0.00 0.00
## ZMYND10 0.30 0.74 0.78 0.76 0.61 0.55 0.85
## ABCB5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ARX 0.05 0.04 0.00 0.00 0.03 0.02 0.01
## SLC25A13 17.30 29.62 21.51 26.95 30.24 22.66 21.18
## ST7 29.40 52.94 41.08 42.85 51.41 38.09 32.58
## CDC27 10.38 15.55 10.65 14.82 18.23 9.91 9.43
## SLC4A1 0.01 0.02 0.00 0.01 0.00 0.00 0.00
## CALCR 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## HCCS 110.61 79.68 62.13 67.83 92.03 62.65 78.56
## DVL2 27.87 33.89 25.39 30.48 38.76 23.82 27.76
## PRSS22 1.24 1.24 1.70 1.86 2.56 1.54 1.23
## UPF1 19.62 25.67 19.07 23.34 26.73 19.75 19.38
## SKAP2 7.06 12.53 8.66 13.68 14.79 8.71 9.49
## SLC25A5 684.85 886.68 832.37 856.00 820.57 830.87 758.97
## CCDC109B 8.97 8.74 8.04 6.41 6.36 12.07 7.96
## HOXA11 11.44 10.70 8.53 8.64 9.41 8.66 9.15
## POLR2J 208.37 217.09 291.86 227.51 201.11 274.27 216.56
## DHX33 13.16 19.63 15.74 18.80 20.83 14.04 12.55
## MEOX1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## THSD7A 0.10 0.00 0.07 0.06 0.04 0.01 0.03
## LIG3 5.64 8.26 6.11 7.05 7.54 5.06 6.32
## RPAP3 34.90 44.63 42.61 37.45 41.49 40.02 35.13
## ACSM3 0.73 0.46 0.16 0.41 0.91 1.38 0.76
## AC004381.6 9.58 9.55 6.91 8.05 8.06 6.42 8.10
## CIAPIN1 72.28 94.72 78.34 88.83 105.31 84.26 71.79
## FAM214B 2.89 1.52 0.95 2.10 4.84 1.58 2.06
## COPZ2 18.31 25.75 21.80 16.48 13.92 20.21 19.60
## PRKAR2B 0.14 0.03 0.06 0.01 0.02 0.03 0.05
## MSL3 12.60 22.31 19.24 21.73 20.81 20.10 16.45
## CREBBP 3.10 5.23 3.96 5.34 7.18 3.36 2.76
## BZRAP1 1.55 2.88 3.19 2.26 1.41 1.83 2.03
## MPO 0.03 0.01 0.02 0.00 0.03 0.00 0.04
## PON1 0.01 0.21 0.11 0.06 0.09 0.05 0.02
## GCFC2 21.55 20.99 23.97 18.10 17.96 21.97 22.31
## WDR54 13.79 35.42 31.32 27.37 16.16 29.11 19.82
## CROT 5.40 3.52 3.92 4.55 5.00 4.90 5.18
## ABCB4 0.02 0.00 0.01 0.01 0.00 0.01 0.01
## KMT2E 5.35 6.15 5.32 6.00 8.63 3.37 4.43
## RHBDD2 52.05 57.84 39.86 54.61 64.46 52.09 46.93
## SOX8 0.82 3.88 1.90 1.60 1.14 1.85 1.28
## IBTK 7.66 8.31 7.89 8.02 11.25 8.18 8.31
## ZNF195 18.94 24.09 22.19 24.07 26.14 21.07 18.81
## MYCBP2 6.12 14.78 9.77 12.85 16.17 8.67 8.90
## FBXL3 19.61 21.85 16.69 19.61 29.55 18.17 17.13
## ITGAL 0.05 0.00 0.00 0.02 0.01 0.00 0.10
## PDK2 9.42 14.99 11.93 16.94 17.02 15.89 11.55
## ITGA3 12.93 16.72 11.11 21.92 33.39 15.49 18.59
## ZFX 3.74 6.64 4.52 5.31 6.15 4.43 3.20
## LAMP2 53.77 44.65 34.34 46.94 72.14 34.98 40.94
## GGNBP2 22.88 27.37 24.78 25.40 27.11 23.05 22.64
## ITGA2B 0.03 0.08 0.17 0.07 0.03 0.36 0.30
## ASB4 3.20 4.02 3.13 3.53 2.62 2.94 3.07
## GDE1 29.96 32.22 23.74 29.30 47.08 21.89 28.81
## C19orf60 95.49 79.09 81.78 85.31 64.84 87.56 85.84
## CRLF1 2.39 2.83 2.71 3.16 3.86 2.67 1.71
## OSBPL7 5.06 3.82 3.76 6.39 4.77 3.16 4.73
## TMEM98 6.89 8.78 7.54 4.86 4.93 5.60 4.58
## YBX2 2.30 4.48 4.40 3.67 2.33 3.74 3.24
## KRT33A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ABCC8 0.32 0.28 0.39 0.10 0.11 0.04 0.19
## CCL18 0.00 0.00 0.00 0.00 0.00 0.00 0.03
## CCL3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SYNRG 6.44 5.70 4.26 5.08 7.17 3.72 3.94
## CACNG3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMEM132A 18.53 29.91 23.27 21.16 12.90 20.71 18.81
## AP2B1 29.88 33.02 22.63 29.80 36.31 21.95 24.65
## TAC1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZNF263 14.74 18.55 13.53 16.39 21.51 12.28 13.29
## CX3CL1 1.89 3.69 2.08 0.91 1.14 1.37 0.84
## SPATA20 15.44 20.68 20.95 18.06 15.19 15.99 20.38
## CACNA1G 0.02 0.01 0.01 0.04 0.02 0.00 0.01
## TNFRSF12A 140.74 145.00 132.53 129.92 159.62 119.85 118.80
## DLX6 1.44 1.19 0.71 0.76 0.76 0.76 0.90
## MAP3K9 1.66 1.96 1.30 2.19 3.15 1.24 1.55
## RALA 36.00 47.68 39.49 42.34 46.86 41.31 38.66
## BAIAP2L1 18.50 22.18 16.62 19.33 24.79 15.68 15.21
## KDM7A 1.00 1.54 1.01 1.13 1.88 0.92 0.88
## ETV1 8.22 8.93 6.87 9.70 11.79 5.79 5.41
## AGK 20.04 24.32 21.57 24.18 24.66 19.15 17.91
## ALDH3B1 16.14 25.08 16.10 19.30 16.61 16.81 23.52
## TTC22 0.01 0.01 0.00 0.00 0.00 0.02 0.01
## PHTF2 6.30 10.77 8.95 9.16 10.34 8.05 6.61
## CCL26 2.99 8.61 7.36 11.18 14.24 10.12 6.89
## FARP2 7.06 6.32 5.01 7.55 9.66 4.44 4.27
## USH1C 21.58 48.69 40.49 37.78 25.65 43.30 38.86
## GGCT 152.30 137.68 135.34 144.12 162.37 149.43 155.65
## DBF4 23.73 30.19 26.31 26.53 31.26 28.02 21.33
## TBXA2R 0.16 0.45 0.10 0.14 0.19 0.17 0.15
## IFRD1 42.49 45.41 41.32 46.68 67.07 40.99 38.46
## LGALS14 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## COX10 11.20 9.53 8.33 9.57 12.31 7.66 8.41
## GTF2IRD1 11.10 43.27 25.44 27.26 25.87 29.88 21.15
## PAF1 21.97 43.89 32.35 32.20 30.45 35.38 25.41
## VPS41 13.49 10.67 11.54 13.84 13.65 7.64 9.43
## ARHGAP44 0.30 0.95 0.49 0.45 0.24 0.57 0.34
## ELAC2 30.51 48.00 37.32 48.29 50.79 39.38 35.53
## SCIN 0.07 0.05 0.02 0.06 0.06 0.04 0.04
## ARSD 9.84 6.67 6.22 5.24 5.68 5.40 6.53
## PNPLA4 51.47 29.94 35.96 29.59 34.81 30.17 34.27
## MYH13 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## ADIPOR2 24.02 37.65 28.10 32.86 44.74 24.03 25.87
## CDKL3 1.68 0.91 0.71 1.09 1.95 0.79 1.62
## UPP2 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## PRSS21 0.03 0.00 0.00 0.00 0.04 0.00 0.00
## MARK4 2.29 3.43 1.92 2.88 2.81 2.37 2.38
## PROM1 6.07 14.33 10.99 8.38 7.25 9.64 8.09
## CCDC124 146.55 184.19 160.47 190.18 192.35 191.75 163.55
## CEACAM21 0.18 0.15 0.32 0.08 0.05 0.22 0.09
## PAFAH1B1 53.16 49.54 43.74 44.57 69.53 37.67 43.54
## NOS2 0.00 0.01 0.00 0.00 0.00 0.01 0.00
## DNAH9 0.01 0.00 0.00 0.01 0.00 0.02 0.00
## KIAA0100 16.30 52.45 28.38 40.73 34.28 25.24 25.61
## SLC13A2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GAS7 0.21 0.66 0.48 0.31 0.10 0.61 0.15
## TRAPPC6A 23.94 16.60 14.89 14.63 18.20 14.07 21.82
## MATK 0.56 0.03 0.03 0.00 0.12 0.03 0.08
## CEACAM7 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## CD79B 0.10 0.04 0.34 0.00 0.08 0.11 0.02
## SCN4A 0.06 0.03 0.06 0.01 0.04 0.01 0.01
## ST7L 21.77 20.57 15.58 14.96 19.41 15.33 16.75
## TKTL1 0.20 0.07 0.08 0.20 0.10 0.15 0.07
## PAX6 7.12 6.82 5.36 6.81 9.21 5.66 6.15
## RPUSD1 25.53 64.50 51.92 62.43 42.71 64.19 34.63
## RHBDF1 14.03 9.91 9.26 10.41 11.69 8.25 10.74
## LUC7L 8.99 19.47 20.53 17.44 13.23 19.18 11.36
## CACNA2D2 0.23 0.21 0.12 0.18 0.15 0.17 0.32
## BAIAP3 2.00 1.33 1.03 2.07 2.31 1.24 2.43
## TSR3 97.39 106.45 86.15 102.29 104.21 99.62 92.18
## PIGQ 6.64 13.14 12.29 16.21 8.95 14.23 10.94
## CRAMP1L 3.06 4.81 3.74 4.14 6.36 2.97 2.80
## TEAD3 2.65 4.58 2.93 3.12 4.72 2.59 2.59
## SELE 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DNAJC11 23.70 36.64 27.80 32.95 31.35 26.44 23.66
## FMO3 0.04 0.43 0.41 0.17 0.11 0.34 0.15
## MYLIP 3.52 4.09 2.72 2.74 3.30 2.29 2.24
## NOX1 0.05 0.07 0.06 0.13 0.17 0.11 0.16
## E2F2 2.66 6.51 3.72 4.13 2.05 3.41 2.44
## PSMB1 191.66 168.64 157.38 170.38 182.12 171.55 170.62
## SYN1 0.38 0.54 0.28 0.35 0.32 0.40 0.30
## JARID2 2.78 2.95 2.04 3.29 3.39 2.20 2.44
## CDKL5 0.18 0.15 0.12 0.21 0.29 0.10 0.07
## CAMK1G 0.11 0.01 0.00 0.00 0.04 0.00 0.06
## CDK11A 24.58 24.34 18.90 23.20 24.51 18.57 20.42
## NADK 20.23 36.63 31.38 33.05 33.71 28.02 26.22
## TFAP2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TFAP2D 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DLEC1 0.07 0.03 0.02 0.12 0.09 0.04 0.05
## CYTH3 2.69 4.12 3.34 4.80 5.93 3.14 3.09
## ADAM22 1.15 2.05 1.82 1.44 1.15 0.89 0.88
## SYPL1 41.54 56.40 51.96 49.28 63.57 56.27 45.55
## CYB561 34.09 46.83 35.14 43.02 45.18 34.70 35.38
## SPAG9 13.58 14.67 11.72 13.59 21.82 9.18 10.93
## CELSR3 3.06 5.46 3.95 4.20 3.99 3.35 3.61
## AASS 0.50 0.43 0.35 0.39 0.48 0.20 0.45
## PLEKHG6 0.58 0.91 0.31 0.32 0.23 0.34 0.31
## SS18L2 29.88 31.61 39.58 32.19 32.32 36.63 36.15
## MPND 16.71 24.83 17.71 20.68 14.47 19.99 20.85
## MGST1 80.26 86.23 95.73 80.29 89.32 88.91 85.48
## CRY1 9.58 9.16 8.01 7.50 9.94 8.31 6.89
## PGLYRP1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NFIX 6.85 16.73 9.51 15.04 15.10 9.19 8.02
## ST3GAL1 0.49 0.59 0.52 0.49 0.49 0.60 0.58
## MMP25 0.21 0.15 0.16 0.05 0.13 0.22 0.20
## IL32 7.64 4.20 5.03 2.74 4.32 2.89 4.92
## PKD1 7.24 9.52 10.00 15.24 14.46 9.11 10.41
## MAPK8IP2 0.40 0.89 0.61 0.81 1.03 0.94 0.44
## MED24 38.97 55.63 41.47 55.52 59.41 44.88 42.51
## RHOBTB2 5.14 8.18 5.04 8.49 8.72 5.92 5.39
## HEATR5B 2.39 2.94 2.26 3.25 4.14 2.34 2.46
## SEC62 51.40 55.97 48.58 43.98 53.92 47.20 39.85
## RPS20 2850.49 2151.01 2985.04 2407.66 2261.24 2957.06 2940.14
## CSDE1 110.27 130.15 103.22 121.44 146.80 96.93 98.03
## UBE3C 33.62 45.49 33.19 42.30 47.91 32.08 27.44
## REV3L 2.72 3.92 4.14 3.35 4.14 3.66 2.93
## TENM1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PAX7 0.01 0.01 0.00 0.00 0.01 0.00 0.00
## MASP2 0.36 0.67 0.40 0.53 0.50 0.35 0.39
## IYD 0.09 0.00 0.00 0.00 0.00 0.00 0.00
## FAM76A 5.39 6.34 5.74 5.55 6.26 5.04 4.69
## TRAF3IP3 2.16 3.00 2.14 2.50 2.50 2.39 2.40
## POMT2 5.28 4.81 3.05 5.01 6.22 3.10 3.44
## VTA1 33.15 32.44 29.81 32.44 37.22 28.94 27.01
## MLXIPL 2.88 2.67 3.86 3.92 3.33 2.04 3.44
## BAZ1B 17.83 33.39 22.95 27.97 33.40 19.51 17.13
## RANBP9 12.11 23.65 19.85 22.02 26.25 17.82 13.95
## ETV7 0.88 0.86 0.63 0.40 0.27 0.83 0.39
## SPRTN 3.14 5.50 4.76 6.46 5.63 5.36 3.87
## METTL13 29.87 31.94 27.09 27.58 40.18 26.59 26.98
## DYRK4 44.09 44.85 50.99 35.46 24.76 43.82 41.30
## ZNF207 74.79 114.69 108.14 101.55 90.10 98.96 65.79
## UQCRC1 119.40 203.90 169.53 172.97 165.78 175.62 158.22
## STARD3NL 31.86 43.89 40.37 40.14 39.59 39.14 36.02
## CD9 227.41 369.17 330.15 280.25 266.51 301.29 256.01
## HHATL 0.07 0.00 0.12 0.06 0.03 0.04 0.06
## NCAPD2 17.38 37.95 23.62 28.83 32.95 21.77 22.18
## IFFO1 0.16 0.17 0.31 0.24 0.25 0.19 0.19
## GIPR 0.60 0.42 0.57 0.55 0.69 0.33 0.79
## PHF7 8.30 6.94 3.73 5.73 8.75 4.65 7.27
## SEMA3G 0.11 1.11 0.63 0.45 0.25 0.48 0.29
## NISCH 7.92 7.23 7.35 9.54 10.89 6.37 6.97
## STAB1 0.07 0.02 0.00 0.07 0.02 0.03 0.14
## FUZ 0.28 0.35 0.13 0.16 0.20 0.22 0.24
## SLC6A13 0.08 0.00 0.00 0.07 0.17 0.02 0.09
## IDS 26.83 18.93 16.60 23.62 37.60 17.27 21.48
## PRSS3 16.55 31.39 34.60 28.85 20.25 31.64 21.71
## ZNF200 7.43 7.04 5.59 6.22 8.38 4.89 5.74
## CD4 4.06 8.35 6.12 5.17 3.63 5.25 4.86
## LRRC23 31.30 33.40 26.72 31.36 33.18 33.15 39.96
## BTK 0.00 0.01 0.00 0.00 0.00 0.00 0.01
## HFE 2.05 3.97 2.70 2.86 2.25 2.64 2.97
## SCMH1 5.95 15.93 13.89 13.97 6.40 11.02 9.38
## FYN 59.93 144.75 107.36 121.54 95.61 109.23 88.19
## HIVEP2 1.93 2.10 1.74 1.74 3.08 1.09 1.30
## FMO1 0.00 0.03 0.00 0.02 0.01 0.00 0.03
## TCEB3 18.46 22.26 16.57 21.18 27.80 16.77 17.15
## LYPLA2 64.73 81.10 67.65 82.76 83.20 82.55 70.76
## CLCN6 2.80 1.77 1.83 1.74 3.17 1.28 2.06
## MRC2 0.10 0.12 0.06 0.05 0.08 0.12 0.29
## NME2 499.75 542.06 992.92 829.78 547.55 609.00 693.76
## SLC6A7 0.00 0.05 0.00 0.00 0.08 0.00 0.01
## TSPAN9 7.85 16.71 10.95 11.45 10.53 9.78 7.59
## BTBD7 6.52 8.42 6.51 8.11 9.95 6.25 6.01
## APBA3 4.79 9.14 5.54 7.84 7.28 8.06 6.36
## MKS1 14.10 13.65 13.21 14.44 14.14 12.21 14.50
## ABHD5 8.72 6.91 7.03 7.91 11.35 5.79 6.95
## KAL1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## AKAP8L 27.73 22.01 16.88 23.25 37.79 17.83 23.40
## MBTD1 1.50 2.99 2.09 2.33 3.55 2.03 2.17
## UTP18 36.47 60.63 48.29 51.59 58.71 51.10 44.38
## RNF216 10.24 15.28 10.90 13.63 13.75 10.06 10.62
## TTC19 35.69 24.84 20.41 19.94 23.77 19.60 25.90
## PTBP1 133.15 183.86 150.56 204.40 213.48 154.91 129.20
## DPF1 3.78 4.57 4.11 4.39 3.94 5.22 2.60
## SYT7 1.07 1.74 0.92 1.18 0.97 0.71 0.65
## LARS2 7.55 11.54 7.86 9.37 10.79 7.07 7.33
## PIK3C2A 7.57 8.65 8.19 8.27 14.29 6.14 5.58
## PLAUR 54.01 39.77 31.37 40.96 54.29 36.87 40.41
## ANLN 11.23 43.35 34.56 33.53 25.53 33.32 17.45
## WIZ 11.61 16.34 11.24 15.69 17.73 11.60 9.08
## RABGAP1 3.86 8.91 6.00 7.26 7.79 4.86 4.89
## DCN 0.06 0.00 0.00 0.00 0.00 0.00 0.00
## QPCTL 9.95 15.44 7.66 12.05 14.31 10.82 16.03
## PPP5C 43.12 76.67 63.62 63.55 60.00 60.27 45.98
## CEP68 4.91 3.60 2.65 3.78 4.68 2.66 3.47
## MAP4K3 3.74 4.63 4.16 5.15 6.13 4.40 3.39
## ZBTB32 0.57 0.36 0.13 0.26 0.30 0.29 0.31
## TYROBP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMEM159 2.97 1.27 0.79 1.53 3.66 1.05 1.77
## GABRA3 0.04 0.13 0.16 0.07 0.06 0.31 0.05
## BRCA1 18.36 30.25 22.38 24.64 24.75 21.05 20.51
## ERCC1 45.29 39.77 37.49 39.97 42.72 41.65 35.11
## CD22 6.40 8.57 4.43 7.54 11.56 4.99 8.59
## MBTPS2 13.77 16.63 12.60 13.78 15.27 11.86 10.81
## PRICKLE3 11.55 11.56 9.32 11.63 17.30 8.53 10.17
## LTF 0.46 0.33 0.09 0.18 0.13 0.23 0.23
## EXTL3 6.10 8.05 5.02 7.33 9.10 5.05 5.06
## NR1H4 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## ELOVL5 43.40 60.08 50.90 51.16 64.68 48.61 47.26
## ALOX5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## KDM5D 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CALCOCO1 14.16 26.26 21.54 21.38 21.65 16.84 22.69
## UBR7 20.86 31.42 25.04 26.00 29.74 23.81 22.57
## MAP4K5 5.95 11.95 11.24 11.32 12.07 9.81 7.80
## EHD3 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## PSMC4 119.99 150.68 129.99 141.30 149.96 138.91 128.78
## MAN2B2 7.94 11.55 6.78 9.30 10.75 6.89 8.08
## SLC7A14 0.00 0.00 0.01 0.00 0.00 0.06 0.01
## CLDN11 46.84 48.37 38.48 46.64 51.57 43.51 44.91
## SLC25A39 124.59 223.97 179.42 203.71 188.30 200.92 165.02
## MVP 45.51 59.42 35.99 54.11 60.49 47.11 47.95
## NUB1 57.96 69.58 58.22 66.56 68.36 61.30 50.52
## PGM3 24.70 19.08 14.86 16.79 21.10 12.78 19.06
## RWDD2A 4.37 3.40 3.04 3.43 4.59 2.71 3.64
## CLK1 12.75 14.06 13.52 12.50 18.81 13.06 13.89
## POLR3B 4.28 6.69 5.73 6.32 7.99 5.07 4.98
## ANGEL1 12.32 6.23 5.36 6.78 12.84 4.22 8.37
## RNF14 37.24 24.96 18.01 25.29 37.52 21.12 23.42
## DNASE1L1 20.36 24.69 21.00 24.23 26.82 19.84 22.59
## DDX11 29.81 42.27 44.60 57.04 60.79 33.81 37.29
## HEBP1 44.54 38.64 34.48 39.43 44.43 41.66 45.29
## GPRC5A 17.61 35.64 22.95 29.23 32.78 19.45 17.28
## MAMLD1 1.79 2.82 2.08 3.63 2.90 2.22 2.02
## CD6 0.53 1.39 0.88 0.78 0.31 0.82 0.64
## TACC3 21.47 42.43 32.47 32.85 28.08 32.84 23.36
## UFL1 10.33 8.14 8.59 7.12 9.54 6.97 7.54
## POLA2 49.44 100.65 81.87 76.82 56.45 88.29 55.42
## ZC3H3 5.14 4.93 4.20 5.21 5.25 4.02 3.90
## CAPN1 50.40 88.38 54.95 78.07 64.82 74.82 69.55
## ACPP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MDH1 122.92 154.62 166.22 144.41 142.81 155.62 153.20
## SLC30A9 16.11 34.60 28.10 27.51 24.16 29.86 21.88
## MTMR11 4.69 5.31 4.28 5.13 6.29 3.76 4.66
## COX15 24.13 25.15 17.09 22.95 28.75 18.13 19.92
## CCDC88C 5.88 5.03 3.70 6.01 7.08 4.61 4.32
## YAF2 7.91 9.00 8.22 8.91 10.09 8.89 7.23
## ZMYND11 4.14 8.94 9.03 8.43 8.54 8.81 5.92
## WAS 0.23 0.09 0.03 0.17 0.24 0.20 0.07
## DPEP1 0.53 4.05 3.94 2.05 0.72 3.15 1.34
## BID 29.78 37.13 37.52 39.03 43.52 34.68 39.15
## MATR3 144.49 190.95 160.89 170.06 197.29 165.54 139.37
## NPC1L1 0.06 0.09 0.06 0.08 0.08 0.05 0.05
## XYLT2 3.15 2.00 2.03 2.52 3.64 2.07 2.99
## RGPD5 1.45 1.31 0.70 1.47 0.50 0.41 0.93
## STMN4 0.00 0.00 0.00 0.00 0.00 0.04 0.00
## NUDCD3 16.94 24.09 17.35 20.13 20.33 16.21 19.93
## ISL1 0.82 0.51 0.55 0.58 0.51 0.56 0.94
## CHDH 6.92 11.68 9.04 10.58 8.90 7.69 7.04
## IL20RA 13.89 21.61 20.69 22.96 20.25 19.06 19.44
## CLCA1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CLCA4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GLT8D1 43.76 50.90 41.62 42.03 53.85 44.13 49.46
## ATP2C1 20.22 37.56 23.70 28.26 36.88 23.00 24.71
## SRCIN1 0.98 1.35 0.73 0.76 0.57 0.77 0.60
## IGF1 0.00 0.00 0.00 0.04 0.08 0.00 0.02
## SLC38A5 167.40 420.13 308.57 366.50 325.05 330.83 247.61
## MAGIX 2.47 3.07 2.86 2.91 1.67 2.61 2.64
## RALBP1 16.28 21.69 14.79 20.83 26.86 16.65 15.74
## RUFY3 6.09 3.60 3.67 4.00 5.04 3.08 3.64
## CNTN1 0.02 0.03 0.08 0.00 0.03 0.00 0.01
## SLC11A1 0.36 0.28 0.23 0.13 0.25 0.15 0.47
## WWTR1 4.75 7.38 7.06 7.45 9.50 4.28 4.13
## AGPS 8.62 14.54 12.43 13.58 15.36 11.41 9.64
## CXorf56 40.37 36.99 26.32 33.56 45.91 32.03 31.39
## ATP1A2 0.01 0.00 0.00 0.08 0.01 0.00 0.02
## TTC27 21.40 28.50 18.77 21.42 24.85 22.01 20.45
## ZNF582 0.08 0.00 0.00 0.01 0.01 0.00 0.00
## VSIG2 0.04 0.00 0.00 0.00 0.02 0.02 0.00
## PHLDB1 10.00 24.69 19.28 23.15 25.94 17.08 16.04
## MARCO 0.44 0.71 0.36 0.42 0.71 0.37 0.58
## CYP24A1 0.16 0.12 0.05 0.06 0.13 0.04 0.14
## PRDM11 2.21 4.27 2.83 4.04 4.83 2.91 2.32
## SYT13 1.32 5.19 3.74 3.32 1.94 2.69 2.25
## SNAI2 4.00 6.65 6.08 5.22 5.03 6.17 4.23
## CD74 0.07 0.02 0.08 0.09 0.06 0.00 0.07
## HGF 0.00 0.01 0.00 0.00 0.01 0.00 0.00
## ZRANB1 3.67 6.54 4.87 5.53 6.54 4.40 4.35
## NCDN 17.03 20.80 14.38 23.50 34.27 15.33 15.67
## GPR124 0.18 0.50 0.23 0.24 0.10 0.26 0.12
## ZFP64 7.64 9.87 7.01 11.40 14.85 10.03 9.27
## MNAT1 59.28 44.89 48.83 42.09 43.38 50.87 53.67
## SAMD4A 0.99 0.91 0.56 0.44 0.54 0.39 0.50
## RUNX3 8.52 24.97 16.03 20.56 16.43 16.41 11.05
## MRE11A 11.44 18.13 13.96 14.94 16.01 13.05 10.88
## PLEKHB1 11.43 60.78 49.41 36.79 19.80 42.09 23.13
## SERPINB1 58.47 65.09 59.09 44.74 39.49 51.07 50.16
## CYP3A43 0.00 0.00 0.05 0.00 0.00 0.00 0.00
## SLC7A9 0.04 0.04 0.04 0.03 0.00 0.12 0.09
## SPAST 3.83 4.21 3.68 4.03 6.51 4.08 3.47
## NRXN3 0.08 0.05 0.00 0.03 0.04 0.00 0.02
## OSBPL5 1.03 2.29 1.88 2.49 1.54 1.52 1.09
## AQR 15.59 15.40 9.37 13.26 17.67 11.68 14.55
## CPS1 0.02 0.03 0.07 0.06 0.00 0.07 0.01
## C8B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## FHL1 5.22 11.64 9.63 8.33 5.35 8.53 4.60
## RTFDC1 138.90 135.22 113.23 120.98 129.85 106.46 118.80
## GABRA1 0.10 0.01 0.06 0.00 0.00 0.01 0.00
## NLRP2 0.00 0.00 0.02 0.00 0.00 0.00 0.00
## SLC45A4 2.24 2.30 1.86 1.84 3.85 1.42 1.55
## RNF10 41.89 55.36 34.27 50.77 60.58 42.74 47.21
## ZNF839 5.64 5.61 4.42 6.03 5.80 4.23 6.32
## ZDHHC6 17.81 18.35 19.16 16.42 19.08 18.35 10.97
## GRAMD1B 2.14 11.49 8.43 8.73 4.23 7.92 3.43
## RNH1 138.08 137.17 106.03 137.88 161.88 124.97 152.53
## NDUFS1 34.13 33.43 26.92 26.35 26.47 22.37 26.43
## RB1CC1 6.01 8.88 6.40 7.06 12.51 6.95 7.23
## ERP44 17.45 17.57 14.33 16.48 21.15 16.22 19.00
## ALAS1 32.77 47.60 37.68 39.95 41.04 36.08 33.12
## BIRC3 2.51 3.76 4.46 2.20 2.44 2.24 2.66
## AKAP11 0.96 1.82 1.73 1.45 1.76 1.18 0.96
## GLRX2 36.48 39.21 50.76 39.86 45.34 46.51 39.04
## SNAPC1 4.28 3.99 4.11 4.24 6.42 4.38 4.24
## DERA 60.86 69.13 59.41 61.26 58.81 56.63 56.99
## STRAP 268.21 217.95 226.14 233.83 321.26 245.12 227.51
## ABCC2 2.78 3.77 3.29 5.04 7.76 2.87 3.21
## DEF6 16.10 17.02 12.79 17.46 19.06 15.63 13.76
## PLEKHO1 4.31 6.56 5.97 4.07 4.03 4.08 4.36
## GCLM 19.50 11.79 11.26 20.16 44.68 13.87 15.26
## UBR2 3.34 4.70 3.74 4.13 5.87 2.81 3.29
## EHD2 0.56 1.29 0.68 1.10 1.40 0.83 0.89
## DEPDC1 2.76 3.63 3.34 3.40 3.74 2.94 2.49
## CCDC28A 9.36 8.69 8.45 8.27 10.65 8.13 10.01
## RRAGD 19.15 9.55 6.70 7.37 12.46 7.26 9.76
## HSF2 7.31 7.51 6.91 7.40 7.94 6.84 5.60
## PHF20 5.13 6.41 4.53 6.11 7.47 4.54 4.87
## HSD17B6 0.25 1.70 1.73 1.23 0.82 1.46 0.90
## NR1H3 25.80 30.31 27.25 32.83 31.01 27.78 27.72
## TYMP 1.07 1.42 1.66 0.56 0.56 1.14 0.83
## NCAPH2 28.61 53.66 39.82 37.85 29.75 38.71 31.39
## TOMM34 105.54 89.14 73.87 98.67 121.03 84.26 90.46
## SEC63 27.74 36.31 25.74 28.05 46.12 29.93 34.97
## KPNA6 9.94 13.35 8.11 11.57 13.35 8.11 9.23
## VIM 430.48 454.31 358.34 445.42 372.53 410.41 343.21
## RTEL1-TNFRSF6B 0.81 1.07 1.55 1.79 1.03 1.13 1.30
## FAS 3.43 2.58 2.80 2.71 3.60 2.57 2.57
## RNASET2 29.75 29.30 27.67 30.33 34.18 26.52 31.30
## CD44 29.46 25.39 18.36 20.39 19.44 14.82 15.59
## KCNG1 0.00 0.00 0.00 0.03 0.00 0.02 0.02
## AGPAT4 0.04 0.10 0.02 0.10 0.06 0.04 0.06
## SLAMF7 0.56 0.09 0.28 0.16 0.12 0.20 0.15
## BTN3A1 3.42 4.27 3.75 3.60 3.75 2.58 4.30
## MIPEP 13.59 21.93 16.47 17.38 15.98 19.65 17.54
## PRKCH 0.14 0.13 0.14 0.11 0.20 0.09 0.04
## INSRR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## IFNGR1 17.58 18.00 14.98 17.28 27.46 14.47 16.50
## B4GALT7 21.87 20.10 17.36 19.84 20.13 18.87 20.16
## SH2D2A 11.28 7.99 6.23 5.42 4.77 5.93 7.58
## VRK2 18.01 18.17 18.74 19.93 22.20 16.88 16.44
## TNFRSF1B 14.25 42.24 26.98 31.25 20.75 26.73 21.18
## VEZT 15.54 18.22 16.93 15.44 16.75 15.38 13.16
## POU2F2 0.87 0.64 0.39 0.81 0.41 0.45 0.35
## BRD9 31.78 31.98 28.47 39.38 36.30 31.49 32.48
## SNX1 30.63 41.52 37.09 32.72 27.91 32.13 25.41
## TBPL1 16.44 15.55 15.64 14.60 18.82 18.36 14.28
## ARNTL2 17.00 20.96 16.66 18.51 15.93 15.20 16.64
## BCLAF1 32.82 47.20 31.73 40.40 35.37 29.13 21.16
## SLC39A9 19.29 23.55 14.98 20.92 29.59 16.33 21.10
## ANK1 0.27 0.61 0.55 0.23 0.21 0.18 0.18
## IBSP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TFB1M 11.15 17.12 17.14 15.64 15.99 17.74 17.98
## RABEP1 20.69 32.80 29.70 28.00 27.81 25.07 24.13
## HMGB3 178.88 185.49 165.30 169.89 150.26 196.01 177.16
## NUP160 26.15 33.92 28.92 27.03 34.24 23.94 20.05
## BAK1 23.07 14.81 12.34 15.71 26.41 12.80 13.91
## MUSK 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## IKZF2 0.58 0.10 0.13 0.13 0.17 0.02 0.05
## GRN 135.94 153.45 85.52 131.04 203.28 117.04 130.09
## FAM13B 1.57 3.28 3.05 3.41 5.23 2.61 1.64
## ARHGAP31 0.03 0.07 0.07 0.13 0.09 0.17 0.04
## CENPQ 6.05 10.75 11.04 9.26 8.89 11.32 7.50
## SARS 96.07 95.39 78.91 94.33 117.24 86.82 90.29
## RANBP3 21.67 42.47 35.89 33.64 31.25 29.70 20.01
## ARID4A 1.86 2.78 1.70 2.00 3.61 1.69 1.84
## TSSC1 28.88 32.30 26.10 26.38 21.17 25.16 22.09
## PNPLA6 9.45 39.89 20.81 24.22 17.56 26.88 21.03
## IFT88 3.08 6.02 5.50 4.60 4.70 5.63 5.30
## ALG1 28.75 49.45 34.00 42.33 44.35 38.50 32.18
## ZCCHC8 7.68 8.84 8.19 8.98 12.13 7.58 7.19
## ABCF2 57.08 90.08 68.77 86.80 101.11 67.51 58.91
## CHPF2 22.82 24.90 18.21 25.51 32.41 20.19 22.69
## LRRC7 0.04 0.08 0.04 0.05 0.13 0.16 0.13
## FUT8 13.48 22.53 17.22 20.24 19.51 17.53 20.60
## UBA6 5.39 10.15 9.75 11.09 10.13 7.27 6.28
## GAB2 3.70 4.36 2.23 4.26 5.29 2.72 3.51
## ATP6V0A1 14.27 22.53 14.35 21.18 28.12 17.21 21.21
## PIAS1 3.90 8.18 7.63 6.48 7.50 6.40 4.95
## SLC4A7 1.84 2.86 2.65 2.63 3.97 1.87 1.72
## APBA2 3.53 1.84 1.24 0.93 1.07 0.81 1.39
## MAP2K3 39.22 42.34 28.10 36.83 49.35 31.53 33.92
## EFCAB1 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## TMSB10 4713.66 4291.46 5622.47 4728.86 4257.84 5639.69 4773.19
## ASTE1 4.67 5.02 4.38 4.96 5.25 3.96 4.17
## RNF19A 3.36 7.09 4.66 5.67 5.92 3.55 3.39
## PEX3 17.77 20.40 18.92 19.05 23.92 18.56 22.31
## GABARAPL2 172.57 181.47 175.71 164.35 200.86 181.96 185.97
## MYOC 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SH3YL1 1.58 1.45 1.09 1.40 1.78 0.92 1.63
## FAM136A 98.06 103.72 100.95 107.38 119.11 103.44 88.30
## VCL 46.36 70.01 49.42 53.81 51.87 35.99 38.24
## DEPDC1B 5.39 20.18 16.93 13.88 8.42 15.62 9.53
## DAPK2 0.28 0.60 0.50 0.35 0.13 0.54 0.11
## NSMAF 11.41 15.31 12.84 13.61 15.84 12.74 11.92
## ADSS 18.59 25.53 22.47 23.54 26.92 23.41 19.83
## STAP1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TIMP2 39.60 80.00 49.99 83.77 76.48 62.61 50.25
## RFC1 22.40 29.32 21.57 26.00 28.11 22.86 23.56
## TBC1D23 9.22 12.20 11.53 8.67 11.34 10.35 9.83
## CUL3 42.46 60.91 51.18 50.81 63.57 55.66 47.01
## MYOM2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## OTC 0.05 0.00 0.00 0.00 0.00 0.01 0.00
## CYP46A1 0.08 0.02 0.04 0.08 0.07 0.05 0.18
## ZZZ3 14.95 17.05 12.99 19.14 27.71 12.94 13.17
## SLC18A1 0.00 0.02 0.01 0.02 0.00 0.01 0.00
## USP2 0.68 0.32 0.11 0.40 0.46 0.18 0.29
## CASR 0.00 0.00 0.00 0.00 0.04 0.01 0.00
## TUBG2 3.27 4.04 3.42 3.43 2.41 3.16 3.98
## RPL26L1 132.64 104.04 139.06 127.27 111.50 139.61 135.57
## FLT4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NSUN2 69.02 105.46 88.45 92.00 102.31 80.55 69.57
## FBXO42 3.96 5.62 4.71 5.49 6.03 5.32 4.89
## MFAP3 4.50 5.39 4.27 4.66 6.76 3.87 3.54
## MRI1 14.32 20.33 18.15 19.86 17.99 17.54 15.38
## METTL1 63.98 67.38 64.47 65.27 61.05 66.68 53.09
## HOXC8 1.95 1.42 0.90 1.45 2.27 1.49 1.42
## AGA 7.21 10.40 7.33 8.76 8.26 8.55 10.02
## PI4K2B 11.65 11.95 12.21 11.31 9.98 12.68 10.57
## BOD1L1 5.39 6.66 5.79 6.10 7.29 4.03 5.43
## MAT2B 34.41 35.49 35.44 33.32 43.72 35.33 33.68
## TLL1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## EDC4 55.06 82.93 65.07 76.09 81.61 62.84 63.99
## TRIO 7.57 12.00 10.11 11.91 11.77 8.47 8.24
## VCAN 0.05 0.00 0.00 0.04 0.03 0.00 0.01
## CLEC16A 6.21 9.53 5.21 7.50 7.98 5.88 7.15
## MSR1 0.00 0.02 0.00 0.00 0.13 0.00 0.00
## CDH1 12.89 18.60 13.23 8.81 8.12 8.65 9.71
## SKIV2L2 33.09 49.67 36.26 41.50 47.51 34.02 33.83
## DNAH5 0.95 1.50 1.61 1.37 1.01 1.92 1.58
## ZFYVE16 5.66 9.01 6.98 6.85 8.52 6.51 6.71
## FAM65A 29.78 41.27 22.20 44.46 45.46 27.99 30.33
## C6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RAI14 6.88 10.07 7.45 8.47 8.48 6.47 6.07
## SOX30 0.11 0.22 0.12 0.14 0.07 0.16 0.22
## PNKP 19.64 32.60 24.88 23.94 15.49 23.19 20.68
## BEST2 0.02 0.08 0.03 0.03 0.01 0.01 0.00
## PHLPP2 2.23 2.54 2.21 2.40 3.79 1.60 1.74
## SPDL1 12.22 15.11 15.03 14.47 13.72 12.55 11.25
## STAU2 6.59 11.39 8.94 8.22 5.35 7.15 5.82
## PQLC2 13.22 13.20 9.12 11.92 16.09 9.56 11.10
## CTNS 8.07 11.36 9.86 13.76 17.88 10.13 8.69
## RTN4R 3.44 7.58 5.37 6.08 6.53 5.42 5.04
## PHF23 29.14 41.24 31.19 34.23 39.86 35.27 27.23
## CDH10 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## INPP4A 0.93 2.21 2.11 2.10 2.39 1.60 1.36
## RAB27B 0.12 0.00 0.00 0.00 0.01 0.01 0.07
## PSMA4 192.10 220.79 209.13 205.25 200.23 224.49 216.30
## MYO16 0.12 0.06 0.06 0.06 0.13 0.12 0.06
## LSG1 43.05 38.59 32.35 42.39 54.75 30.06 34.34
## PARP3 4.70 4.10 5.88 4.64 4.51 4.02 4.28
## TNC 6.61 44.62 32.84 23.08 13.70 21.51 9.70
## THAP3 13.41 13.28 11.79 13.25 14.64 13.11 12.13
## FAM65C 0.07 0.01 0.03 0.00 0.04 0.02 0.02
## TDP1 8.61 12.95 9.66 10.26 14.06 9.52 9.67
## AIFM2 19.75 24.21 18.91 22.83 25.43 20.40 19.28
## C2orf83 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SPATA7 6.48 5.14 5.01 4.79 4.75 5.15 5.54
## MED17 25.68 36.67 30.66 31.03 43.35 30.34 27.07
## RETSAT 6.94 13.41 9.94 13.41 14.12 9.31 10.77
## CAPG 90.32 99.56 87.21 82.84 86.18 84.92 93.13
## AP2S1 197.96 226.56 234.40 235.76 219.36 236.83 191.73
## USH2A 0.01 0.01 0.06 0.01 0.01 0.01 0.01
## ZPBP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TG 0.00 0.06 0.00 0.05 0.01 0.00 0.00
## ADAM28 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## BARX2 0.26 0.23 0.15 0.22 0.06 0.23 0.15
## DCUN1D1 10.66 10.05 9.42 10.09 14.63 8.22 9.58
## JADE2 9.66 18.74 11.39 15.19 18.27 10.70 8.38
## ZIC2 0.79 0.16 0.10 0.10 0.45 0.06 0.32
## LCP2 0.01 0.00 0.00 0.00 0.00 0.11 0.00
## TRIT1 24.93 25.18 19.14 22.27 25.15 20.56 21.27
## ADRB1 0.06 0.02 0.06 0.01 0.06 0.03 0.06
## GUCA2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CUL7 1.97 3.19 2.26 2.72 2.43 1.92 3.36
## CTNNA1 58.99 86.92 71.10 77.34 94.08 65.20 67.88
## PHKA2 7.31 7.86 6.50 8.38 10.06 6.06 9.05
## CNTLN 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## EPHA3 0.03 0.15 0.10 0.08 0.06 0.09 0.07
## HSPA5 473.75 373.38 279.55 297.98 333.16 302.69 397.97
## DSG2 10.54 18.16 15.25 16.02 21.40 11.36 10.14
## GEMIN8 11.15 15.79 14.87 16.79 16.56 15.24 15.35
## OFD1 13.58 15.38 12.56 15.09 17.90 13.86 15.96
## GPM6B 0.07 0.13 0.08 0.08 0.09 0.08 0.03
## MAGEC2 0.37 0.05 0.07 0.01 0.08 0.03 0.05
## PREX2 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## WDR37 5.22 5.24 3.98 6.43 9.14 4.29 5.02
## YTHDC2 3.46 6.28 5.56 5.29 5.80 4.36 3.39
## CTPS2 12.73 15.88 12.67 14.71 14.56 12.30 13.01
## ATP6V1H 28.54 21.28 17.81 20.72 30.46 18.97 20.71
## POLR2B 28.41 47.22 39.82 42.60 53.38 36.23 32.42
## FAM214A 2.87 2.33 1.99 2.62 4.71 1.80 3.11
## ARAP2 1.36 2.67 2.30 2.02 3.33 1.39 1.41
## TPR 13.90 21.19 17.73 18.74 19.88 14.27 16.34
## CP 0.04 0.12 0.02 0.01 0.05 0.04 0.02
## KIAA0556 3.36 3.89 3.60 4.00 3.86 2.75 3.59
## DTNBP1 11.75 15.85 13.21 15.64 17.37 14.59 13.86
## XK 1.63 2.63 1.86 2.14 1.79 1.76 1.48
## ANO2 0.06 0.00 0.10 0.00 0.00 0.07 0.01
## C12orf4 10.56 9.69 8.66 8.83 9.95 7.30 6.70
## SCML1 7.72 8.48 12.12 11.03 14.41 11.40 9.19
## WWC3 5.23 2.90 2.45 3.23 3.28 2.71 3.13
## ARHGAP6 0.00 0.02 0.01 0.00 0.00 0.00 0.00
## FAM184B 0.26 0.43 0.29 0.47 0.60 0.28 0.35
## MAP4 24.20 31.41 19.50 30.88 36.25 21.89 27.12
## GOPC 5.21 7.12 7.30 6.76 9.01 6.34 5.36
## ROS1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## USP28 4.88 8.55 7.48 7.37 10.69 5.32 5.70
## HDAC9 3.61 3.34 2.88 3.61 6.76 2.42 2.92
## TSPAN17 36.92 39.13 27.94 44.24 58.92 34.61 30.47
## NOP16 95.52 115.76 115.04 114.30 122.23 111.32 94.37
## CC2D2A 6.92 8.92 6.57 6.73 5.55 6.51 5.34
## RRM2B 5.68 5.63 5.06 6.69 11.22 5.10 5.87
## ZNF800 4.67 6.04 4.30 5.72 8.19 3.90 3.69
## TNFRSF17 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SNX29 3.01 3.46 2.79 2.87 3.25 2.21 2.39
## LMO3 0.01 0.10 0.08 0.02 0.03 0.04 0.06
## MRPS10 68.78 52.75 52.13 59.90 75.81 53.06 57.30
## GUCA1A 0.02 0.00 0.02 0.00 0.00 0.00 0.00
## RSF1 8.17 9.04 6.69 8.68 11.95 6.08 6.87
## VPS13D 3.34 4.93 3.21 3.91 5.56 3.14 4.14
## CELF2 0.00 0.00 0.00 0.00 0.01 0.02 0.01
## FAM120A 22.21 24.06 19.32 25.67 36.71 21.95 20.03
## R3HDM1 8.93 18.29 12.72 16.62 19.98 13.67 10.72
## COL9A2 0.86 0.59 0.49 0.41 0.56 0.27 0.52
## KITLG 0.76 0.88 1.29 1.10 0.90 0.84 0.52
## ERCC8 6.42 8.73 8.13 8.35 8.27 8.01 6.28
## ADAMTS6 0.00 0.12 0.03 0.09 0.07 0.02 0.01
## H6PD 3.66 3.74 1.96 2.60 2.77 1.93 2.84
## VAMP3 53.43 45.45 39.32 45.55 60.43 45.02 46.11
## PER3 1.26 1.65 1.37 0.90 0.97 0.87 0.96
## UTS2 0.00 0.00 0.05 0.00 0.00 0.03 0.05
## TNFRSF9 0.62 0.06 0.07 0.03 0.04 0.07 0.19
## EPN3 0.06 0.23 0.12 0.04 0.02 0.05 0.09
## LTBP1 0.05 0.06 0.04 0.05 0.08 0.06 0.09
## RCN1 84.19 104.51 80.35 86.18 89.58 85.11 85.59
## ELN 0.02 0.03 0.00 0.03 0.01 0.10 0.11
## RFC2 81.03 128.06 109.96 100.38 74.42 103.61 79.42
## ARID1B 5.17 7.30 3.90 6.37 7.67 3.88 4.09
## CLPTM1L 107.58 169.52 104.68 149.59 151.42 143.25 110.89
## NEDD4L 24.22 22.95 14.08 21.13 27.72 17.48 18.51
## FOXP3 0.72 0.27 0.21 0.28 0.33 0.12 0.33
## PPP1R3F 1.75 3.48 1.94 1.62 2.07 2.39 1.53
## HEXB 121.66 98.22 80.82 99.15 153.45 91.04 116.00
## PTCD2 4.13 4.02 2.90 4.92 5.31 3.29 4.02
## KIAA2022 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## JKAMP 22.55 26.92 26.54 26.06 31.67 26.44 23.37
## DKK3 1.65 1.76 1.57 1.96 1.55 1.39 1.86
## ARHGEF5 9.58 15.00 9.00 14.06 17.77 10.42 9.94
## NFE2L3 9.71 21.37 14.75 15.07 16.23 14.95 13.02
## MCUR1 36.09 41.07 39.37 45.09 49.54 42.64 41.21
## LIMA1 19.84 26.42 19.22 20.39 33.07 19.80 17.23
## LETMD1 50.36 37.67 37.58 45.03 58.42 36.29 51.88
## SLC4A8 0.28 0.62 0.72 0.26 0.28 0.40 0.35
## LAMC3 0.04 0.19 0.24 0.05 0.13 0.13 0.05
## PTGER3 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## TNIP3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MAPK9 12.93 18.67 15.67 16.75 17.71 18.57 14.08
## COL23A1 0.03 0.00 0.00 0.00 0.02 0.00 0.01
## BCAR1 50.59 79.37 50.40 70.85 79.89 58.73 51.09
## FAM160A2 15.45 15.66 12.37 18.23 19.38 13.61 13.58
## HERPUD1 75.64 88.76 81.23 79.13 106.57 83.37 88.26
## HOMER3 15.71 31.83 22.04 20.39 17.98 24.43 18.90
## RAD51 28.66 50.70 37.42 36.41 32.26 43.75 36.26
## POLQ 1.76 3.39 4.40 3.15 3.07 2.62 1.76
## PIK3CB 9.64 17.63 12.44 15.93 19.25 13.26 12.20
## CYBA 106.90 152.86 155.12 142.78 119.19 161.80 123.43
## THOC3 38.65 57.31 45.44 46.39 49.05 45.00 45.04
## HEBP2 92.62 96.41 101.50 92.44 87.51 105.90 100.59
## MPHOSPH9 7.99 10.56 9.87 9.35 11.83 7.88 7.74
## PLEKHA5 10.44 7.01 7.34 7.20 8.51 8.67 7.45
## PRSS8 0.02 0.05 0.02 0.00 0.01 0.05 0.01
## SIKE1 52.23 22.74 25.29 21.93 25.49 20.76 30.86
## RRP12 64.30 56.47 35.52 50.34 69.18 42.27 56.69
## FNIP2 1.73 2.25 1.73 2.46 3.75 1.47 1.55
## MSMO1 14.14 10.16 9.22 11.06 33.55 10.47 17.01
## TTC17 36.95 48.07 33.99 34.16 44.72 26.77 30.60
## ALX4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## FSTL4 4.03 8.43 6.74 8.78 7.76 6.86 6.57
## FOXN3 1.41 2.10 1.29 1.66 1.79 1.60 0.98
## METTL24 0.00 0.06 0.05 0.03 0.00 0.04 0.02
## AKR7A2 28.26 48.07 39.73 37.02 29.90 38.33 36.85
## MRTO4 107.61 99.02 81.89 96.02 105.35 92.70 79.89
## NNAT 0.26 0.06 0.26 0.30 0.22 0.06 0.13
## USE1 46.65 61.08 70.48 57.53 42.73 58.88 51.69
## MCF2L2 0.45 0.11 0.24 0.13 0.25 0.20 0.09
## NRIP2 0.21 0.29 0.22 0.34 0.42 0.20 0.28
## LAMA3 10.27 32.65 24.54 17.23 21.48 16.35 13.46
## AP5M1 8.90 12.00 10.57 8.93 13.27 9.83 7.29
## ANAPC4 11.14 16.46 14.43 13.95 13.68 13.63 11.33
## KCNQ1 0.10 0.11 0.08 0.13 0.08 0.13 0.07
## TRAPPC3 61.84 71.22 57.82 65.31 81.30 62.07 60.19
## THRAP3 30.75 38.69 26.46 35.90 34.40 24.70 26.39
## PHPT1 77.76 87.73 102.47 82.39 61.64 94.55 85.74
## ENTPD2 0.30 0.34 0.37 0.36 0.25 0.27 0.41
## LY75 2.29 2.88 2.77 2.10 1.99 1.82 1.57
## ARID4B 4.22 5.65 3.38 4.29 5.75 3.61 2.38
## OPN3 1.10 1.40 1.69 1.52 1.47 1.14 1.33
## SDCCAG8 9.41 9.70 8.93 10.34 9.14 8.58 10.53
## PTPRN 0.14 0.03 0.18 0.09 0.10 0.01 0.10
## HHAT 0.42 0.15 0.21 0.20 0.22 0.23 0.11
## KIF1B 4.40 5.60 4.04 4.79 8.08 3.53 3.66
## FOXC1 4.67 4.44 3.86 3.30 3.83 3.33 3.61
## TBC1D22A 14.54 19.87 14.57 15.01 12.79 16.39 13.77
## SYNE2 1.74 4.22 2.89 2.21 1.39 2.29 2.19
## PLEKHH1 1.59 1.37 1.86 1.94 1.77 1.24 1.99
## ATP9A 5.76 7.00 4.62 7.88 11.02 4.64 6.44
## SPO11 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CBLN4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CHRDL2 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## FAM168A 3.74 7.33 4.74 6.64 6.66 4.24 4.61
## RELT 6.24 9.65 7.82 9.98 9.55 8.44 5.75
## GALC 0.86 0.39 0.30 0.29 0.27 0.21 0.32
## NOP58 103.89 102.85 83.76 98.15 102.60 96.08 92.68
## SZRD1 75.40 93.12 72.55 94.62 110.83 82.33 68.38
## KCNH2 6.67 8.96 6.25 6.15 5.87 6.18 4.53
## CUL1 24.53 39.56 31.20 34.35 42.12 28.51 23.75
## FAM114A2 19.51 13.23 10.45 13.21 19.43 8.39 12.71
## CYFIP2 4.01 8.85 5.82 6.09 4.18 6.07 4.51
## TAB2 5.86 9.81 7.54 8.49 11.95 7.27 6.51
## GINM1 18.35 19.65 15.39 16.55 21.15 18.38 17.83
## EIF2AK2 8.25 9.89 9.18 9.68 11.17 7.04 6.07
## USP36 46.98 41.18 30.86 48.24 69.55 32.38 39.57
## KMT2C 3.38 5.63 3.92 5.56 7.49 4.21 4.11
## MCOLN3 0.15 0.13 0.11 0.12 0.08 0.11 0.06
## CCDC85A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PUM2 10.48 18.76 14.86 16.74 23.07 12.66 12.62
## MRPL43 105.65 115.75 102.51 115.22 114.98 122.54 108.99
## ITIH4 0.43 0.26 1.04 1.11 1.38 0.54 0.91
## ITIH1 0.09 0.00 0.00 0.00 0.01 0.00 0.00
## C4orf27 30.70 35.86 32.69 30.63 29.65 37.22 38.86
## ZFR 24.78 17.60 15.99 18.21 32.62 17.33 15.34
## ZNF280C 2.10 2.09 2.27 2.73 3.39 1.84 1.82
## NPFFR2 0.03 0.00 0.00 0.00 0.02 0.00 0.02
## PHF21B 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## TRAF1 0.30 0.16 0.15 0.13 0.23 0.12 0.16
## RC3H2 12.29 12.22 11.11 12.83 11.00 7.00 14.44
## PCGF2 6.83 12.90 8.13 9.37 10.30 11.07 8.14
## IL17RB 23.63 30.06 30.59 26.48 27.81 24.88 18.41
## TRAF3IP2 11.60 5.82 6.69 7.09 9.80 5.54 8.05
## GYG2 0.02 0.14 0.05 0.03 0.02 0.06 0.02
## DCBLD2 52.17 86.52 71.11 86.42 101.45 69.80 68.21
## SERPINB3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SOAT1 5.76 10.01 8.10 8.80 9.22 6.37 4.96
## PKP2 10.47 19.56 11.87 15.08 17.63 13.49 11.19
## MSH4 0.00 0.02 0.00 0.00 0.00 0.00 0.00
## F7 0.06 0.03 0.00 0.00 0.02 0.00 0.03
## GDI2 134.20 162.05 142.01 162.96 179.94 149.48 140.37
## PRDM1 1.46 2.53 1.04 2.35 3.35 1.21 1.75
## ATG5 14.22 16.86 14.84 13.80 17.92 15.21 14.00
## TMCC3 0.01 0.00 0.00 0.00 0.01 0.00 0.00
## PITHD1 38.92 48.01 39.89 52.99 78.26 50.60 43.44
## MTA3 9.96 13.16 11.00 9.58 8.62 11.75 9.31
## USP13 3.64 4.62 2.90 3.77 3.90 2.91 2.40
## ATP11B 3.76 5.03 4.85 5.24 7.12 3.78 3.31
## LAMC2 8.16 15.40 11.62 12.05 13.10 7.71 9.11
## CDK14 0.07 0.14 0.01 0.01 0.07 0.00 0.02
## SEC61A1 133.89 154.18 102.26 120.59 161.31 101.05 114.93
## PPP1R12A 7.44 9.65 6.00 7.43 12.54 5.97 5.33
## RASGRF1 0.24 0.21 0.25 0.33 0.35 0.19 0.21
## CAMK2B 0.22 0.24 0.08 0.14 0.14 0.06 0.09
## CROCC 4.59 6.08 4.46 6.68 5.80 4.91 5.93
## POLR3E 14.73 26.71 21.33 24.62 23.44 23.24 22.73
## ATP2B4 1.23 2.09 1.59 1.02 1.55 1.02 1.45
## ZC3H11A 10.72 17.91 14.30 15.09 19.82 11.78 11.76
## RIOK2 25.93 24.27 21.49 20.32 30.75 21.41 20.50
## YIPF1 18.43 20.99 17.76 22.56 27.12 20.38 20.12
## NDC1 15.77 28.12 21.93 24.82 27.36 20.30 16.85
## DGKG 6.14 9.93 8.67 10.38 9.47 6.92 7.09
## FLYWCH1 11.75 14.07 9.84 16.62 20.76 13.07 13.34
## UNKL 2.71 3.08 3.68 2.65 3.96 3.83 3.00
## TBXAS1 2.17 2.07 1.78 1.77 1.67 1.03 1.28
## PARP12 6.35 8.09 6.71 5.86 4.03 5.86 5.32
## ALDH18A1 64.72 60.92 41.75 53.49 73.57 45.16 58.47
## TARBP1 7.07 14.46 13.04 15.03 13.28 12.90 14.31
## PET112 21.04 29.04 22.91 23.88 21.42 23.39 24.81
## MXD1 2.63 2.66 1.82 2.51 5.12 1.99 2.89
## CDK17 5.45 6.66 6.32 8.17 9.82 5.83 4.77
## DNAJC25 15.45 12.61 14.65 9.46 7.84 15.95 15.49
## SLC2A3 59.30 41.94 38.00 61.08 98.92 37.78 57.71
## PSD 2.75 2.28 2.38 2.01 1.83 1.91 1.87
## CTDP1 3.80 5.68 3.60 5.09 5.39 4.34 4.28
## YBX3 207.13 209.88 172.56 216.05 235.33 196.95 186.77
## STYK1 0.69 0.50 0.59 0.77 1.45 0.79 0.57
## WNK1 12.94 35.67 30.12 36.26 33.68 21.08 17.85
## CCAR1 17.41 23.79 24.74 20.01 28.69 24.95 18.18
## OGFR 26.31 43.27 28.91 37.43 38.08 38.23 27.95
## GNA15 0.00 0.02 0.06 0.00 0.00 0.03 0.00
## CREB3L3 0.05 0.83 0.46 0.73 0.45 0.61 0.30
## PIGV 4.54 6.73 4.40 5.14 5.08 4.13 5.12
## PTPRU 1.17 1.64 1.02 0.65 0.61 0.73 1.06
## SNRNP40 49.07 60.76 48.70 53.25 62.46 54.75 50.39
## RIMBP2 4.99 8.15 6.64 7.37 5.16 4.80 5.37
## COL11A1 0.07 0.14 0.02 0.17 0.03 0.14 0.03
## QSER1 4.74 8.08 7.18 8.27 11.49 6.54 5.74
## MPC1 20.93 31.97 38.44 30.74 26.66 38.22 33.72
## ACAA1 59.99 57.67 46.68 60.27 68.06 49.80 55.30
## BCAT1 0.24 0.02 0.02 0.08 0.13 0.05 0.03
## HDAC7 13.09 16.74 13.62 18.45 21.48 14.50 15.00
## LZTS1 0.02 0.03 0.08 0.04 0.01 0.03 0.04
## PRDM6 0.00 0.00 0.02 0.00 0.00 0.01 0.00
## WNT8A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SPAG4 6.27 4.26 3.96 3.50 2.96 3.09 4.92
## NCKAP1 24.67 28.83 24.04 26.79 37.89 21.39 24.81
## MRPS35 106.64 113.37 104.65 103.51 119.43 99.33 96.37
## GUCY1B3 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## SFSWAP 16.01 17.48 13.07 15.09 15.98 12.85 13.80
## TNK2 13.73 35.25 25.84 34.09 28.80 29.09 20.79
## MON2 2.75 3.63 2.15 2.26 4.08 2.18 2.23
## CDH3 0.23 0.08 0.02 0.01 0.11 0.08 0.05
## ARSF 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GPBP1 42.22 39.26 28.91 34.18 50.05 30.56 37.32
## DGAT2 2.89 4.00 2.89 3.13 3.19 2.82 2.11
## ZNF112 0.55 0.96 0.55 0.67 0.92 0.37 0.52
## CS 146.54 168.15 138.77 177.75 186.16 130.07 136.75
## LTK 0.33 0.14 0.22 0.17 0.24 0.21 0.26
## MRPS24 204.99 235.13 228.23 228.35 224.07 253.78 227.01
## ELMO2 13.36 11.68 9.00 13.29 18.17 9.76 11.34
## WAPAL 12.09 16.46 13.43 14.89 21.16 14.09 13.57
## VMP1 101.54 74.26 89.55 84.05 94.69 69.88 95.12
## APPBP2 2.60 6.17 3.94 4.52 6.23 3.42 2.96
## POLD1 20.75 70.36 56.51 61.45 36.04 59.10 47.37
## SEZ6 0.03 0.05 0.02 0.02 0.11 0.05 0.05
## EIF4B 205.60 251.95 158.75 216.64 261.12 174.41 185.71
## SLC6A16 0.08 0.11 0.11 0.13 0.08 0.03 0.17
## GLTSCR1 2.71 2.55 1.05 2.43 3.98 1.81 2.16
## SPHK2 5.89 7.76 5.65 8.32 9.40 6.90 5.81
## RPL18 2911.30 2229.21 2405.80 2344.33 2359.84 2430.74 2744.42
## CA11 6.10 5.05 3.41 3.66 3.66 3.02 6.45
## ISOC2 81.11 69.58 62.59 74.09 74.36 66.51 79.95
## U2AF2 152.36 156.81 118.07 157.52 184.90 121.57 124.73
## EPN1 41.25 69.54 41.67 59.11 60.30 56.57 47.55
## MED29 30.03 21.87 24.14 22.81 23.99 18.69 20.21
## AHRR 5.12 14.80 9.71 12.84 10.45 8.86 7.36
## GSC2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZNF275 3.90 4.30 3.23 4.38 6.26 2.99 3.15
## MTMR1 8.95 22.21 17.67 18.36 18.47 14.27 10.50
## GPC1 15.21 25.82 17.72 23.35 20.25 19.81 15.95
## ADCK1 4.68 7.52 5.88 6.96 5.98 5.85 5.63
## HAGH 13.52 24.83 22.25 17.71 11.24 21.89 19.90
## RNF4 28.05 32.85 25.58 31.73 38.91 25.58 21.80
## CASP8 15.34 12.93 11.69 12.89 14.59 11.03 11.20
## LIMCH1 0.01 0.02 0.01 0.02 0.06 0.07 0.16
## ASUN 69.67 91.13 85.10 92.32 118.99 102.71 86.15
## TM7SF3 67.94 109.27 84.36 90.32 107.08 69.37 67.10
## DLX3 2.98 4.78 3.59 3.27 3.39 3.36 2.85
## SPA17 3.96 7.92 9.63 5.71 2.54 7.62 5.47
## TSPAN32 2.92 7.10 6.89 4.43 1.77 5.49 4.08
## WISP2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DMRT3 0.06 0.00 0.00 0.01 0.00 0.00 0.00
## ST3GAL6 0.34 0.32 0.25 0.24 0.62 0.30 0.41
## ATP2C2 0.25 0.12 0.10 0.41 0.35 0.25 0.21
## NGFR 12.47 7.00 3.67 3.61 3.53 3.34 3.51
## CDON 2.45 2.28 2.04 3.04 2.91 1.72 2.24
## TAF2 9.81 11.89 8.56 10.15 13.99 7.54 7.83
## HIPK2 1.01 2.62 1.52 1.86 1.78 1.42 1.00
## TNPO3 21.48 27.79 21.14 26.57 33.70 16.86 17.66
## MEF2BNB-MEF2B 3.28 2.40 2.17 2.88 4.04 2.82 3.26
## RFXANK 52.71 73.82 65.95 61.39 49.66 67.13 56.75
## TMEM161A 15.04 25.31 19.97 22.46 27.04 23.26 20.61
## LPAR2 7.31 9.84 6.60 9.58 12.26 7.77 7.52
## CTSA 156.69 184.09 130.93 179.83 224.92 160.08 153.63
## SUGP2 10.03 15.51 13.44 17.56 18.76 12.35 13.68
## SLC12A2 3.34 7.34 5.00 7.06 7.22 4.99 3.64
## SNX24 5.83 3.91 5.21 4.66 4.67 4.68 4.10
## EYA2 0.02 0.01 0.00 0.00 0.00 0.01 0.02
## CNN2 133.55 218.05 169.03 227.42 219.06 174.92 131.55
## ABCA7 4.62 6.20 7.44 5.19 5.58 6.16 6.69
## SNCAIP 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## DDX20 6.68 8.79 6.92 7.23 8.20 7.07 6.44
## BTBD1 24.96 30.52 30.59 27.63 32.45 29.08 22.70
## FAR2 0.33 0.82 0.58 0.63 0.72 0.21 0.60
## BCAS1 0.03 0.01 0.06 0.01 0.03 0.01 0.02
## POU1F1 0.03 0.03 0.00 0.04 0.00 0.02 0.00
## CHI3L2 0.22 0.17 0.20 0.10 0.08 0.27 0.21
## SBNO2 4.91 7.71 6.41 7.05 6.02 5.74 5.96
## PMS1 8.39 8.80 7.17 7.01 7.81 7.54 8.95
## HMG20B 11.62 36.23 28.71 33.82 26.79 33.30 27.22
## CALCRL 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TAF11 22.95 27.31 23.32 22.72 24.95 24.46 21.46
## ANKS1A 1.24 3.46 2.42 2.79 2.79 2.21 2.17
## AP3D1 21.45 31.73 19.38 30.10 27.51 23.77 21.87
## ZNF76 7.03 11.40 9.69 11.24 12.71 8.64 9.10
## SLC9A3R2 16.23 26.02 17.42 25.15 28.76 21.90 23.82
## NTHL1 20.14 32.74 28.58 29.40 23.13 30.23 28.57
## UHRF1BP1 2.74 3.44 2.47 3.16 4.19 2.19 2.24
## GNAI3 53.48 57.54 50.84 55.94 70.48 52.04 52.10
## IPO5 90.74 153.41 113.47 138.88 155.88 104.04 93.77
## OAT 50.89 43.02 39.88 40.32 59.69 42.48 37.86
## WDR3 33.27 31.32 23.73 31.05 49.46 22.01 25.08
## PKN2 4.03 5.68 6.13 6.06 7.76 4.92 4.73
## WDR18 27.17 48.67 35.20 40.02 29.33 39.46 34.21
## TRAM2 3.06 5.65 4.00 5.73 5.87 3.43 3.21
## NTN1 0.04 0.04 0.01 0.03 0.03 0.04 0.03
## GLP2R 0.06 0.00 0.01 0.06 0.02 0.00 0.00
## MCM10 13.06 25.89 19.87 21.95 17.05 16.94 12.02
## DGKA 1.80 6.07 5.19 6.30 3.45 6.22 4.04
## ERBB3 5.22 12.80 8.23 9.17 7.83 8.65 9.23
## ROPN1 0.00 0.02 0.07 0.00 0.00 0.05 0.00
## ANKRD44 0.75 0.72 0.64 1.04 0.55 0.50 0.42
## KARS 471.90 551.44 428.75 509.36 572.99 461.00 446.17
## ADAT1 70.85 85.17 54.74 73.69 81.86 53.79 64.37
## PDIA5 12.87 17.25 13.22 12.77 13.21 13.45 15.65
## TBC1D22B 3.98 3.93 3.06 3.85 5.88 3.19 3.49
## NDUFB4 158.82 201.46 256.36 200.38 169.07 231.72 191.77
## SPEN 8.12 12.89 9.04 10.62 13.02 8.36 7.83
## MYLK 0.20 0.22 0.14 0.13 0.13 0.11 0.30
## ZC3H15 68.84 56.15 54.64 59.66 76.46 56.76 56.35
## MAP2K4 5.85 6.34 4.94 6.13 8.32 5.08 5.29
## TMEM206 5.16 5.75 3.80 4.28 6.09 4.96 5.15
## SNAP91 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## SLK 7.36 10.88 8.98 9.44 13.16 7.72 7.76
## CYB5R4 6.30 10.27 10.57 9.02 7.53 10.11 7.07
## COL17A1 0.99 2.39 1.91 2.13 1.14 1.49 2.02
## GSTO2 74.70 65.96 69.21 53.59 52.27 63.26 71.49
## SEC61A2 3.00 2.89 2.50 3.11 3.68 2.19 2.97
## PRKCQ 0.37 0.36 0.24 0.26 0.18 0.22 0.25
## TLE2 0.18 0.17 0.23 0.26 0.11 0.33 0.18
## ASB1 39.59 34.90 25.76 26.52 34.47 23.36 29.96
## FAM107B 8.91 4.71 4.48 6.43 8.26 5.82 4.98
## ME1 8.47 8.95 7.01 10.18 14.44 9.18 8.61
## TBC1D1 10.04 30.94 22.01 19.86 11.11 20.11 13.44
## CDK13 4.33 7.06 5.07 6.69 9.90 5.71 5.22
## MTHFD2 51.97 65.51 64.21 60.92 82.53 57.82 50.30
## SLC9A7 4.81 3.93 2.41 3.27 4.04 1.59 3.11
## FOXJ2 5.67 5.33 3.63 5.77 9.85 3.42 4.73
## YBX1 675.94 1035.51 1012.35 1095.68 950.47 1152.66 878.39
## PDE4A 1.43 5.13 3.34 3.93 2.71 2.94 2.40
## PPP2R5A 21.56 19.99 15.79 19.87 33.90 18.12 20.66
## CTNNA2 0.09 0.40 0.39 0.10 0.11 0.24 0.11
## ELAVL1 43.20 62.68 47.58 54.83 56.12 50.50 42.32
## TIE1 0.15 0.20 0.05 0.05 0.26 0.28 0.12
## DIP2B 5.74 7.82 6.39 7.36 10.26 4.69 4.91
## SMARCD1 44.39 57.46 45.23 55.39 62.73 42.50 36.48
## KDM4A 3.99 7.05 4.18 6.69 8.16 4.81 5.06
## NFYC 18.39 19.90 16.64 21.78 22.48 17.79 17.92
## ZMYND12 0.52 0.53 0.26 0.26 0.36 0.19 0.27
## SLC9A3 0.22 0.20 0.21 0.22 0.23 0.16 0.12
## NGEF 7.80 7.52 5.88 6.13 4.84 6.14 6.28
## ASPM 1.23 4.89 4.24 3.56 3.33 3.65 2.47
## CD84 0.00 0.00 0.00 0.00 0.00 0.00 0.02
## ELOVL1 115.65 93.01 79.10 104.59 118.25 81.33 82.67
## SPI1 0.23 0.08 0.05 0.05 0.06 0.04 0.09
## ZNRD1 117.44 52.02 59.47 57.09 83.22 58.61 79.27
## MPPED2 0.00 0.00 0.00 0.00 0.00 0.00 0.03
## CLDN18 0.01 0.01 0.00 0.00 0.02 0.01 0.00
## ZBTB11 3.90 4.91 4.65 4.62 5.98 4.65 3.56
## ATXN3 11.66 7.12 5.50 6.52 11.01 5.80 8.28
## GOLGA5 14.57 19.12 15.79 13.83 18.33 15.46 16.91
## FGFR2 0.01 0.02 0.03 0.04 0.05 0.01 0.00
## LRRC40 5.23 8.35 9.45 7.52 9.47 8.86 6.62
## ISOC1 17.78 21.93 19.52 16.91 21.17 19.41 19.64
## EML1 0.90 0.30 0.36 0.25 0.31 0.37 0.51
## TRMT11 8.78 12.90 10.64 9.38 8.55 9.44 10.56
## THUMPD1 13.20 15.82 12.77 15.05 18.17 12.60 11.92
## MSANTD3 26.47 32.27 26.23 30.02 36.19 28.57 26.67
## KIF26A 0.07 0.61 0.47 0.37 0.11 0.27 0.18
## ATG2B 1.39 1.92 1.63 3.06 3.41 1.58 1.42
## ARFGEF1 6.76 10.82 7.65 9.09 11.64 9.23 10.52
## ACSM2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZFAT 2.21 3.71 2.25 2.73 2.66 2.40 2.48
## MTFR1 16.22 18.09 13.98 17.25 24.54 15.55 16.53
## STAG3 0.36 0.38 0.58 0.67 0.50 0.30 0.38
## FECH 8.33 7.36 4.75 7.60 6.84 6.45 5.96
## MYO9A 0.77 1.83 1.68 1.89 2.57 1.08 1.18
## DDX3Y 0.00 0.00 0.00 0.01 0.00 0.00 0.00
## PFKP 30.45 49.58 39.47 44.48 34.33 35.21 30.45
## IDI1 23.41 19.69 18.28 19.57 38.29 20.25 23.73
## SP100 38.78 31.83 25.74 31.97 41.69 28.12 32.98
## KLF6 9.48 7.76 6.48 8.83 18.02 5.07 9.11
## PPAP2A 6.28 13.91 11.42 10.33 7.11 11.20 8.28
## NEO1 7.65 11.74 7.44 12.94 14.01 6.33 7.53
## TRAM1 60.46 66.43 51.24 63.52 90.06 49.26 54.01
## PHKA1 5.21 8.79 6.28 8.07 9.00 5.31 5.81
## TNFRSF1A 33.57 40.93 28.47 37.14 61.88 29.87 31.91
## CACNB1 1.27 3.07 1.76 2.70 3.29 2.00 2.06
## EVI5 3.49 3.55 2.11 4.57 5.51 2.29 2.36
## STOML1 8.47 5.83 5.12 6.57 8.52 5.84 7.55
## PKM 650.79 1316.55 1003.92 1238.43 1141.40 1138.72 745.86
## DHX29 20.49 16.29 12.48 15.51 21.99 13.41 14.65
## DNTTIP2 59.01 53.10 42.19 45.88 57.72 50.63 50.20
## METTL22 14.76 12.64 13.35 13.83 15.86 12.89 14.04
## TP53BP1 7.87 12.48 8.43 9.61 11.82 6.94 8.57
## TRO 0.04 0.04 0.01 0.03 0.02 0.06 0.07
## RRP15 35.89 27.53 24.87 24.50 31.00 22.92 21.40
## RHOA 253.22 327.11 290.18 337.43 366.91 339.41 304.83
## DHX8 17.50 19.17 12.93 18.01 24.76 14.26 16.01
## PRKCZ 10.16 14.80 10.57 13.97 16.52 13.67 13.20
## ZFY 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## IARS2 30.74 44.32 35.77 40.77 47.24 34.96 37.97
## SYT1 19.46 34.59 25.39 34.14 36.98 26.01 27.10
## NAV3 1.17 0.06 0.02 0.19 0.24 0.07 0.18
## IDH3G 94.01 116.50 105.10 117.87 105.02 115.86 103.91
## ROGDI 18.45 19.62 15.88 16.67 13.46 16.71 15.14
## PDZD4 0.59 0.71 0.73 0.56 0.37 0.52 0.55
## ATP2B3 0.00 0.00 0.00 0.00 0.00 0.01 0.01
## ROCK1 7.12 8.87 6.95 9.13 13.89 7.00 6.73
## CBFB 57.43 85.30 70.47 79.43 87.74 74.59 45.48
## PDK3 5.59 7.11 6.12 6.70 6.28 5.47 5.48
## HYAL2 21.98 35.62 27.77 27.53 27.86 26.75 22.99
## HDAC4 10.48 17.31 11.89 17.07 17.26 12.83 10.52
## RASSF1 14.43 20.42 17.60 15.44 17.05 14.67 14.22
## FGFR3 0.32 0.40 0.44 0.18 0.17 0.15 0.12
## IFI35 19.83 26.05 22.92 19.61 15.60 20.10 18.34
## HEATR6 7.43 8.75 6.22 7.39 6.08 5.13 6.35
## COASY 59.69 98.59 74.73 76.86 64.86 72.48 82.64
## PLEKHH3 0.30 0.41 0.26 0.35 0.57 0.51 0.43
## MEF2A 5.57 6.01 5.72 5.09 6.69 4.15 4.26
## OTUD5 33.51 50.37 35.28 38.78 45.82 36.98 37.37
## TFE3 16.99 15.00 11.30 14.97 23.84 12.56 11.57
## TBC1D25 3.37 6.09 4.15 6.01 7.74 4.78 5.07
## ACSL4 15.75 13.04 12.08 14.96 23.77 11.20 10.64
## INPP5A 4.39 8.06 6.37 8.39 7.68 7.47 5.47
## GPKOW 33.35 39.37 30.31 34.51 37.61 31.17 34.47
## GRIPAP1 12.88 20.28 15.06 14.84 14.66 13.47 14.91
## FTSJ1 116.87 158.83 135.18 145.38 129.63 143.17 131.87
## PRR11 5.23 10.14 6.61 6.75 5.44 6.94 3.92
## REEP1 0.11 0.39 0.25 0.20 0.02 0.19 0.05
## ATP11A 3.07 6.45 5.19 6.29 5.68 3.85 2.68
## POLR1A 5.30 10.32 7.25 9.94 10.23 5.87 5.18
## LAPTM4A 79.50 72.21 60.08 73.71 107.35 65.47 92.01
## TTC7A 6.24 9.04 5.69 7.71 9.15 6.45 7.35
## IP6K2 28.13 30.83 28.58 30.66 34.75 28.06 28.47
## STON1-GTF2A1L 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SRBD1 4.06 8.40 5.86 6.99 6.83 5.50 5.07
## CYFIP1 17.35 31.03 24.28 28.05 25.63 23.38 25.52
## KIF2A 6.72 19.92 16.74 17.40 13.55 14.33 8.77
## RASGRP2 0.39 0.00 0.09 0.00 0.13 0.16 0.05
## PSME4 21.63 28.29 18.65 21.03 27.56 20.52 22.91
## IFT80 6.23 5.69 6.59 5.41 4.72 3.40 5.17
## SIRT2 20.78 26.42 21.71 25.94 27.47 23.21 23.13
## ERLEC1 25.68 29.96 23.88 23.40 31.58 23.34 30.68
## PPP2R5B 2.13 3.54 2.81 3.29 3.34 2.75 2.78
## PYGM 0.24 0.19 0.06 0.37 0.41 0.11 0.31
## PAGE1 0.04 0.04 0.00 0.05 0.03 0.04 0.00
## PITX1 33.93 59.54 47.77 60.90 60.72 53.42 38.67
## TRPC7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MAST4 1.36 2.34 2.42 2.38 1.96 2.31 1.79
## GPR116 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SDK2 0.02 0.05 0.08 0.01 0.01 0.02 0.00
## ADAM7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NUP133 13.79 18.20 15.42 15.71 18.45 16.74 14.03
## NUCKS1 54.50 62.99 43.57 62.65 54.89 53.21 63.28
## VPS35 72.64 83.28 61.30 77.95 105.24 58.74 71.03
## DNAJA2 67.36 69.86 56.97 63.60 73.11 58.78 56.21
## BCL3 1.98 1.25 1.21 0.75 0.95 0.68 0.79
## KCNAB2 36.42 45.17 32.32 50.23 52.64 34.05 41.33
## ABCC9 0.01 0.01 0.01 0.01 0.02 0.07 0.02
## GAL 215.27 261.00 243.08 244.53 233.40 280.61 213.62
## CLEC2D 1.11 1.02 1.39 0.74 1.73 1.44 1.34
## FUNDC1 29.40 25.14 24.60 23.67 24.95 26.90 24.91
## MAOB 0.96 4.47 3.89 2.47 1.23 3.29 1.42
## RORA 1.12 0.46 0.47 0.54 0.59 0.46 0.64
## DRD4 0.45 0.15 0.12 0.30 0.29 0.26 0.55
## TGFBR3 0.90 2.35 2.19 3.14 2.88 2.02 1.32
## KIAA1107 0.38 0.30 0.20 0.32 0.47 0.31 0.48
## PLA2G10 0.03 0.09 0.04 0.03 0.08 0.05 0.07
## HES2 3.66 0.98 0.81 0.62 1.32 0.99 1.90
## ATP1B3 73.26 199.31 159.32 149.16 145.21 157.93 126.25
## NEDD4 2.86 3.70 3.50 3.79 5.16 2.81 2.27
## PIGB 5.59 7.32 7.02 6.64 4.50 6.57 6.47
## MAPK6 16.20 12.86 9.63 13.93 24.77 10.36 11.43
## GNB5 4.40 11.77 8.07 9.42 7.86 8.14 5.38
## RAB27A 5.99 9.88 8.80 8.05 8.01 8.32 6.86
## CECR5 45.69 54.95 43.09 51.28 51.22 47.25 43.72
## UFD1L 104.76 140.34 142.42 142.44 139.74 145.22 122.18
## LRP6 3.47 6.65 5.49 5.66 6.83 4.33 3.68
## GUCY2C 0.02 0.02 0.04 0.03 0.04 0.02 0.03
## SCT 0.91 0.09 0.24 0.23 0.16 0.10 0.56
## PHRF1 14.40 18.26 11.33 16.21 17.01 13.18 11.82
## IKBKAP 12.22 20.07 16.83 18.11 22.16 13.61 15.10
## NUCB2 85.55 93.76 76.39 78.62 83.75 81.99 113.84
## PFN2 60.66 66.70 53.20 52.98 60.65 53.16 49.98
## PTPN3 3.46 5.78 3.52 4.96 5.41 3.33 4.06
## SPTB 0.78 0.55 0.22 0.58 0.49 0.45 0.38
## DAPP1 0.01 0.00 0.00 0.00 0.03 0.01 0.02
## FGF10 0.01 0.00 0.00 0.00 0.00 0.00 0.00
## SLC44A1 1.92 8.59 6.00 6.13 4.60 4.74 2.90
## TMEM260 3.43 4.54 3.49 3.74 4.24 2.78 3.30
## SMG6 11.55 13.31 10.49 12.98 13.47 11.05 11.17
## EXOC5 8.75 12.86 10.76 10.59 12.83 7.96 6.67
## CLTCL1 0.26 0.43 0.33 0.38 0.34 0.47 0.34
## FGF22 0.14 0.17 0.17 0.20 0.15 0.14 0.10
## FSTL3 6.32 20.42 16.42 16.68 9.14 16.88 9.44
## DGCR2 8.92 14.53 10.40 15.51 15.12 12.00 12.82
## RNF126 24.20 63.87 52.17 55.01 34.95 58.78 29.69
## MNT 7.84 8.23 3.83 6.90 11.74 4.18 8.40
## ZXDC 6.07 8.49 7.27 9.07 8.13 6.79 7.61
## JMJD6 25.13 29.42 24.99 23.07 36.44 23.17 25.29
## POLB 38.15 31.47 34.00 27.57 31.96 32.37 34.11
## ST6GALNAC1 0.07 0.04 0.00 0.00 0.00 0.00 0.12
## WIPI1 13.95 13.15 7.84 14.91 25.99 9.63 16.63
## FRMPD1 0.01 0.02 0.01 0.01 0.00 0.01 0.02
## GBA2 13.13 19.44 19.46 21.61 22.25 16.38 16.64
## NDST1 3.66 3.95 3.21 4.39 6.12 2.15 2.73
## ASNS 36.61 26.62 20.86 25.24 44.25 22.75 31.09
## AP3M2 10.85 10.42 9.72 10.86 9.81 8.12 10.32
## CNGB1 0.02 0.00 0.00 0.01 0.00 0.00 0.00
## ST6GALNAC2 0.33 0.32 0.32 0.24 0.27 0.24 0.35
## CHAT 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PABPC1 679.51 590.33 489.96 710.14 992.95 625.05 679.72
## TESK2 0.67 0.76 0.56 0.68 1.21 0.58 0.56
## C16orf80 49.09 60.90 56.46 50.88 52.41 57.67 49.32
## CSNK2A2 62.74 65.27 45.48 63.48 83.62 50.75 51.59
## PTPN21 1.27 2.20 1.96 2.77 2.70 1.65 1.78
## EIF2B3 28.70 41.28 34.51 36.77 41.38 37.15 35.42
## CAMK2A 0.00 0.04 0.00 0.00 0.00 0.00 0.00
## TCOF1 27.52 56.23 35.49 49.91 45.67 40.97 31.96
## CDC42 180.96 169.49 155.00 186.16 236.96 156.64 159.98
## OSBPL3 6.13 17.58 16.80 16.12 17.41 12.76 10.31
## EPHA8 0.35 1.10 0.66 0.61 0.30 0.62 0.51
## SLC12A3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RAD18 11.71 14.61 12.48 13.34 14.35 10.89 9.86
## ATP2B1 2.78 5.93 3.29 4.43 7.61 2.81 2.38
## TRPM5 0.00 0.01 0.01 0.00 0.00 0.00 0.00
## NCK2 3.36 9.32 6.86 6.45 7.19 6.25 4.64
## MAP4K4 15.11 21.86 15.73 21.89 26.05 14.39 13.99
## MGAT4A 0.20 0.09 0.06 0.18 0.26 0.21 0.03
## RPL31 4709.08 3286.98 4718.17 3560.20 3302.83 3717.12 4809.31
## WDR1 121.53 136.01 102.02 116.32 132.78 96.73 89.15
## SNX13 9.78 7.97 6.36 7.52 8.72 6.01 6.62
## MS4A12 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ARHGAP10 4.55 7.59 4.79 5.82 5.76 4.64 4.67
## RPS6KA2 0.65 1.04 0.91 0.81 0.63 0.51 0.70
## ING3 7.84 9.34 9.18 8.28 8.03 8.82 7.00
## VASH1 0.34 0.84 0.70 0.76 0.42 1.01 0.64
## LMCD1 11.98 19.64 14.24 14.09 13.67 12.42 11.59
## WBSCR22 189.97 173.76 130.85 162.83 202.48 156.54 163.61
## SEL1L 9.39 9.72 9.03 9.52 15.18 7.61 8.87
## TRIP13 37.69 55.43 47.68 45.66 39.64 45.64 40.08
## ATP6AP1 61.95 75.94 53.25 67.04 83.06 57.68 64.44
## TCF3 33.69 72.12 51.80 61.04 56.87 62.48 42.21
## TRIB2 1.67 4.87 4.65 2.75 1.72 3.93 2.11
## DAZAP1 105.90 143.23 108.38 134.69 143.03 132.28 124.84
## MBD3 21.15 50.55 34.12 37.26 29.29 40.26 28.93
## PRLH 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## HLTF 4.45 8.17 6.84 6.41 5.21 5.77 5.69
## FAM50A 92.81 129.34 107.55 119.97 116.17 120.42 125.75
## FAM3A 42.42 49.78 39.06 49.28 52.94 46.78 48.09
## CPSF1 27.21 55.04 53.83 60.59 40.05 51.03 49.11
## MYO3B 0.08 0.07 0.09 0.07 0.12 0.09 0.07
## CYBRD1 1.96 4.15 3.02 2.56 3.36 2.20 2.40
## CDH19 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PDCD2 60.53 68.19 65.46 67.21 76.81 72.16 63.11
## SLC6A15 0.00 0.00 0.00 0.00 0.01 0.02 0.00
## RDH11 20.64 22.73 17.17 19.04 30.97 16.65 18.46
## PRKACA 38.36 47.63 30.70 47.50 55.14 33.94 38.09
## LPHN1 1.72 5.99 3.60 3.34 2.56 3.19 2.08
## SPP2 0.00 0.09 0.00 0.00 0.08 0.00 0.00
## ACTN1 93.86 149.73 101.78 126.55 130.60 96.66 81.63
## ZFYVE26 3.04 3.20 2.79 4.03 5.19 2.25 2.96
## RPS6KA6 0.55 0.52 0.63 0.63 0.65 0.51 0.53
## EPN2 5.68 4.56 4.01 4.59 6.38 3.65 5.32
## PTPN18 29.85 34.07 26.20 35.67 32.27 28.47 32.53
## LIMS2 0.55 0.88 0.74 0.52 0.22 0.93 0.52
## ASIC4 0.27 0.08 0.15 0.07 0.18 0.09 0.33
## SPEG 1.50 0.95 1.38 1.15 1.99 1.33 1.65
## LNX1 0.39 0.33 0.27 0.22 0.37 0.28 0.30
## ALDH3A2 24.08 22.75 19.04 20.32 27.23 17.55 19.48
## TFRC 100.44 171.36 121.60 152.24 210.84 113.10 107.00
## SREBF1 9.08 44.88 24.89 26.98 18.83 25.15 18.97
## TRPC5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## AFF4 4.43 6.72 5.27 6.09 8.42 4.15 3.67
## UBE2D1 15.04 17.79 24.04 18.25 24.64 25.21 16.16
## MPP5 5.88 7.35 5.88 7.16 9.85 5.96 5.33
## RHOBTB1 5.02 3.21 2.95 4.47 4.23 3.04 3.90
## SMC1A 18.28 54.79 40.17 49.74 42.99 27.18 19.61
## HSD17B10 225.92 279.06 272.94 290.47 301.70 311.18 226.28
## MARK2 11.33 18.19 13.82 18.22 22.58 11.98 11.36
## HMMR 8.61 10.01 9.31 8.24 9.88 8.40 6.62
## CHFR 6.79 8.10 6.45 6.91 8.61 6.16 6.48
## TRHDE 0.00 0.00 0.01 0.00 0.00 0.01 0.00
## P4HA2 10.48 14.78 9.29 11.59 16.26 9.80 12.63
## FCGR2B 0.00 0.00 0.00 0.01 0.00 0.00 0.00
## NFATC3 12.91 21.05 11.76 17.61 25.82 13.14 11.96
## TRNT1 19.67 15.15 16.01 11.70 12.11 13.39 12.74
## ACADVL 173.72 332.32 364.07 293.12 215.48 301.49 246.57
## STK10 9.40 16.48 10.48 14.58 17.09 10.09 10.08
## FBXW11 8.14 12.83 8.99 11.61 14.16 8.10 9.62
## ACAP1 10.87 6.29 9.01 6.46 5.12 6.57 12.30
## CRMP1 10.00 19.98 13.67 15.87 13.92 13.89 9.50
## EVC 0.12 0.05 0.06 0.04 0.06 0.06 0.11
## DERL2 119.05 103.68 101.82 94.92 103.11 108.72 96.75
## SIDT1 0.03 0.01 0.02 0.06 0.01 0.01 0.01
## NDE1 10.50 13.10 9.11 13.34 17.99 9.81 9.40
## MRVI1 0.06 0.01 0.01 0.01 0.01 0.01 0.01
## TMEM38A 2.55 6.53 3.63 4.97 6.03 3.59 3.02
## AP1M1 29.51 39.34 29.23 39.51 40.40 31.83 32.24
## PVR 25.83 26.32 19.79 25.10 35.15 18.78 19.36
## IKBKG 25.36 21.75 19.57 30.06 46.33 24.76 24.55
## XRCC1 4.45 16.83 13.88 12.84 7.76 12.79 8.56
## SCARB1 29.05 50.51 32.57 43.44 44.19 38.65 33.43
## CYP2W1 0.13 0.26 0.19 0.31 0.09 0.12 0.17
## MCM2 60.23 116.19 79.37 99.49 86.98 81.09 65.43
## MOV10L1 0.13 0.02 0.00 0.00 0.00 0.02 0.08
## PANX2 0.74 1.07 0.64 1.07 1.39 1.04 1.06
## SELO 9.79 10.40 9.21 14.00 15.77 12.60 16.04
## TP63 0.02 0.01 0.02 0.01 0.00 0.00 0.00
## ALPK1 0.80 0.88 1.01 0.85 0.81 0.64 0.95
## LLGL2 21.73 51.52 44.81 49.17 38.03 42.82 37.17
## PDE8A 7.48 12.42 11.70 11.13 16.02 9.39 8.22
## CLCN4 3.28 3.23 2.25 3.06 3.54 2.09 2.52
## NLE1 17.91 24.08 20.34 21.34 19.59 19.12 15.32
## SDHA 61.85 125.18 90.15 92.96 74.01 95.67 87.74
## SMARCE1 85.88 107.98 90.90 107.99 105.62 91.92 86.14
## FNDC8 0.19 0.11 0.07 0.17 0.22 0.14 0.06
## GSDMB 2.19 2.03 2.96 2.65 3.77 2.42 4.12
## KDM5A 5.17 8.34 4.32 6.68 9.82 4.70 4.61
## ADAM11 0.82 0.50 0.39 0.35 0.27 0.35 0.39
## PPP2R3A 0.33 0.30 0.20 0.30 0.53 0.20 0.21
## FERMT2 8.08 10.17 9.32 8.13 12.19 7.24 6.00
## ABCB11 0.00 0.00 0.00 0.01 0.00 0.00 0.01
## DHRS9 0.02 0.11 0.00 0.00 0.00 0.00 0.00
## CD5L 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PTGS2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## IGF2BP2 4.61 10.44 8.06 11.07 10.87 7.97 6.30
## MAP3K13 47.16 38.58 38.07 36.01 42.66 33.62 40.68
## ST6GAL1 1.32 3.48 2.66 2.29 1.09 2.09 1.77
## TBX21 0.08 0.05 0.01 0.02 0.04 0.04 0.04
## FRY 0.01 0.18 0.12 0.04 0.09 0.03 0.09
## PICALM 56.36 67.84 54.26 61.90 78.25 46.36 45.26
## NSF 12.48 16.07 11.91 14.90 18.99 10.94 11.48
## GLI2 0.24 0.67 0.39 0.65 0.08 0.16 0.15
## CLASP1 6.18 9.46 6.56 9.77 12.58 5.11 6.25
## MRPS34 172.88 262.71 212.40 216.29 187.02 248.94 191.22
## NOTCH3 0.12 0.06 0.00 0.13 0.04 0.08 0.14
## CLNS1A 130.11 169.46 149.28 141.82 161.96 155.23 155.45
## PPP2R2C 1.91 8.10 5.44 7.35 7.08 6.21 4.55
## TEAD2 1.32 8.37 4.66 3.48 2.26 4.90 2.27
## EED 19.72 30.32 30.70 25.50 28.61 26.21 23.52
## CDHR2 4.33 7.88 5.29 5.05 5.10 5.02 5.49
## SNCB 0.72 0.46 0.20 0.18 0.22 0.25 0.20
## TSG101 114.88 121.21 102.20 108.26 116.51 104.23 111.25
## C17orf85 17.98 20.60 14.68 16.51 24.24 13.78 13.80
## ATP2A3 0.30 0.73 0.41 0.32 0.16 0.34 0.23
## CA12 0.09 0.25 0.17 0.17 0.10 0.15 0.09
## MGLL 1.94 1.16 1.28 1.36 1.96 1.09 1.31
## NTN4 0.98 0.41 0.46 0.44 0.77 0.41 0.52
## BCS1L 52.75 61.19 51.11 66.31 75.09 54.65 60.09
## NUAK1 0.25 0.38 0.22 0.34 0.17 0.25 0.18
## DPP8 42.53 24.79 26.25 23.49 26.98 24.58 46.23
## SLC24A1 6.01 3.08 1.64 2.60 3.40 2.19 4.39
## ZNF532 3.97 7.91 6.86 6.37 5.38 4.56 3.25
## SCARF1 0.46 0.18 0.15 0.19 0.37 0.11 0.43
## LMAN1 12.21 17.93 13.52 14.41 20.08 13.18 14.25
## PTPLAD1 53.34 74.19 63.65 66.66 79.98 58.96 56.28
## IPCEF1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZZEF1 4.81 7.17 5.81 8.58 10.04 4.45 5.60
## NOX3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ENO1 1259.70 1710.26 1420.04 1744.23 1799.81 1488.06 1256.06
## SLC12A1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## C19orf10 212.05 181.97 135.89 169.02 197.52 164.00 187.30
## ANO8 0.84 1.48 1.17 1.43 1.22 0.79 0.99
## TUBE1 12.95 7.85 6.39 7.29 9.44 7.37 6.89
## ARHGEF10L 3.82 4.80 3.45 4.24 4.18 3.29 3.62
## TXK 0.05 0.02 0.13 0.09 0.09 0.02 0.02
## WSCD2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## KCNQ2 0.78 0.32 0.22 0.19 0.38 0.21 0.43
## TACR2 0.06 0.25 0.28 0.21 0.20 0.17 0.13
## ACTR6 14.60 15.98 14.82 13.72 17.62 15.07 16.38
## TIPIN 50.47 62.89 56.08 52.08 54.37 57.56 53.34
## SRI 73.57 80.25 72.44 75.94 80.64 80.89 75.97
## EIF4G3 5.05 11.08 7.96 8.01 6.65 6.20 5.10
## NUP37 72.51 54.50 55.50 56.37 64.64 54.02 64.13
## SEMA3A 6.19 17.21 15.26 12.73 8.28 11.48 8.44
## GTSE1 2.57 9.13 7.16 5.99 4.30 5.93 3.87
## SEMA3C 0.29 0.22 0.08 0.15 0.14 0.15 0.14
## TTC38 7.93 10.90 8.77 10.81 11.61 9.09 8.53
## ACAT1 85.11 99.76 91.07 89.39 100.07 85.23 99.11
## GRAMD4 1.38 2.68 1.99 3.19 1.86 1.69 2.21
## CELSR1 1.68 1.79 1.08 1.52 1.25 1.33 1.37
## WNT8B 0.09 0.24 0.18 0.16 0.01 0.08 0.13
## ZNF638 32.94 43.50 30.81 30.33 39.08 29.19 37.25
## SLC25A40 5.33 8.63 7.08 5.62 8.46 6.88 4.53
## TIMM21 21.06 20.83 20.92 19.35 21.22 20.00 17.89
## ADD2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## FGF4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RASAL2 1.97 1.83 1.65 1.97 3.60 1.02 1.52
## VPS9D1 2.36 2.39 1.96 1.98 1.54 1.97 2.16
## ZNF37A 3.05 4.54 4.08 4.50 5.89 3.02 2.52
## MARK3 20.15 24.56 21.27 23.65 31.11 21.90 20.94
## SLC25A3 363.72 354.66 304.78 336.66 362.47 322.33 357.83
## FNDC3B 7.78 6.54 5.05 6.27 8.35 4.68 5.63
## FOSL2 4.94 7.18 6.64 6.85 11.77 4.65 5.02
## CACNG5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CACNG4 0.51 12.97 9.03 9.11 3.17 9.00 5.51
## FRYL 3.43 4.02 3.56 3.91 5.59 2.84 4.22
## TMEM131 4.21 7.10 4.18 6.36 8.74 4.00 4.99
## FSCN1 70.96 63.20 38.61 51.03 53.99 46.94 46.25
## ACTB 4126.71 4102.37 3330.63 4390.61 4355.18 4273.70 3562.88
## MOCOS 2.35 5.12 2.06 2.67 2.96 2.30 2.54
## PLD1 4.24 3.14 2.24 3.41 4.42 2.61 3.74
## ATP12A 0.02 0.06 0.01 0.05 0.01 0.02 0.01
## WDR62 2.66 8.25 6.62 8.13 5.76 6.50 4.67
## DLG1 13.96 21.44 14.78 22.92 20.90 14.97 16.45
## RAB7A 138.94 133.33 107.85 144.43 189.98 116.20 136.77
## BCAP29 26.90 36.92 32.46 33.26 38.27 32.48 24.55
## SEC31B 0.63 0.33 1.38 1.06 0.98 0.63 0.86
## SART3 13.58 19.94 14.83 17.15 18.95 12.67 12.17
## ARHGAP15 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TUBA3D 0.00 0.19 0.04 0.04 0.06 0.01 0.06
## PAX2 0.08 0.02 0.01 0.02 0.04 0.06 0.04
## EXOSC7 69.81 56.90 49.67 57.29 64.13 54.12 64.23
## KIFAP3 10.21 11.60 8.78 9.76 10.55 8.41 10.21
## MKRN2 22.69 22.05 19.46 22.68 27.32 17.74 17.94
## MCM6 63.72 114.90 85.30 93.57 80.86 80.86 73.23
## REXO2 78.96 105.84 96.37 107.54 122.51 108.17 117.01
## RBM7 22.01 20.71 16.22 16.95 24.64 17.81 16.56
## RBMS2 4.72 7.12 4.79 8.85 9.99 4.81 4.28
## BAZ2A 11.95 18.02 11.49 17.74 25.86 9.73 10.38
## PTPN23 4.23 10.12 5.87 9.44 8.91 6.70 6.04
## MLH1 30.47 37.62 30.97 30.76 32.91 30.03 28.61
## UNG 74.16 110.56 87.08 104.12 101.10 86.20 85.55
## FMO4 2.08 1.47 0.99 1.43 0.98 1.49 1.47
## KLHL20 4.87 6.41 4.98 5.00 6.83 3.58 4.00
## RGS11 0.43 0.26 0.24 0.28 0.37 0.19 0.30
## SLC46A1 4.44 8.74 6.58 7.41 6.42 5.56 6.11
## PLXNA2 0.23 0.48 0.34 0.58 0.74 0.23 0.27
## SPAG5 4.54 14.88 11.46 11.50 8.14 9.77 5.88
## ANKRD13A 6.07 8.99 7.50 7.71 7.87 6.54 6.20
## TPD52 49.25 57.68 48.96 62.61 70.04 62.05 53.05
## ACACB 1.06 2.14 1.64 1.77 2.01 1.15 1.44
## TRAF4 29.53 33.73 33.59 37.04 39.21 35.70 25.35
## PAG1 0.90 1.11 0.71 1.26 2.04 0.53 0.71
## GPATCH1 4.38 7.06 5.07 6.06 7.84 5.14 4.80
## ICAM3 21.81 35.59 34.48 34.18 28.75 35.46 31.67
## NT5C2 19.47 16.74 16.80 17.83 26.53 13.13 13.93
## MCAM 9.31 11.70 8.13 7.75 6.06 5.28 5.85
## GPC4 6.10 10.22 7.39 8.42 8.86 5.90 6.67
## MBNL3 1.41 1.86 1.55 1.45 1.29 1.18 0.86
## CAMSAP3 4.09 8.67 6.28 8.86 11.18 7.13 6.80
## RAP1GAP 3.78 6.49 4.13 5.07 5.08 4.31 3.64
## XAB2 24.01 28.02 19.28 22.90 22.50 21.02 22.45
## ARHGEF1 32.07 52.99 40.55 51.23 51.70 47.40 45.82
## STXBP2 39.09 42.92 36.39 36.49 34.83 32.88 34.64
## MAP2K7 5.84 12.23 11.01 12.07 11.74 8.82 8.27
## NMRK2 0.04 0.06 0.00 0.05 0.02 0.00 0.00
## DGKD 4.58 6.99 6.66 6.67 8.61 4.52 5.13
## CTTNBP2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ACTL6B 0.02 0.00 0.03 0.00 0.03 0.00 0.00
## RARB 0.10 0.18 0.09 0.11 0.17 0.15 0.25
## TOP2B 37.23 41.21 31.43 34.66 52.11 32.87 41.84
## TM9SF3 43.79 57.41 36.96 48.13 64.96 37.54 38.68
## NFKB2 7.53 13.42 10.88 9.08 9.01 9.10 7.88
## UBE2T 51.47 107.27 129.67 91.27 62.98 109.25 76.48
## PPP1R12B 0.70 1.08 1.01 0.94 1.07 0.59 0.85
## DNAJC10 19.02 29.50 23.56 27.34 28.51 22.36 23.75
## GTF3C1 24.50 39.53 22.22 29.33 31.54 29.78 27.37
## IL4R 7.40 9.22 6.67 7.20 7.05 4.69 5.58
## USP33 7.01 9.87 8.64 9.01 12.69 9.16 7.36
## PAK3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CAPN6 0.07 1.21 0.78 0.50 0.16 0.40 0.10
## DCX 0.00 0.00 0.01 0.00 0.01 0.01 0.00
## SNRPA 48.84 61.61 56.61 63.91 54.34 59.18 56.06
## SPAG6 0.02 0.00 0.00 0.00 0.00 0.00 0.00
## EXOSC5 39.85 55.50 48.64 51.34 56.87 48.78 49.44
## DYNC1I2 35.96 44.15 39.01 39.42 42.58 34.22 34.82
## APBB1IP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## LRCH4 11.66 24.80 21.77 23.82 21.59 19.58 16.83
## FAM76B 6.91 9.33 7.57 8.54 10.35 5.67 4.75
## SIRT6 26.77 23.61 17.51 23.77 30.01 22.32 21.03
## TYR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## POLD3 15.40 29.18 25.93 22.84 16.44 21.04 16.69
## ACTN2 0.03 0.00 0.00 0.00 0.00 0.00 0.00
## CAPZB 122.29 170.64 144.98 172.51 163.79 151.67 138.53
## GPR137B 2.12 2.11 1.69 1.79 2.55 1.53 1.90
## NAALAD2 0.06 0.17 0.31 0.16 0.26 0.24 0.15
## JADE1 2.89 3.65 2.39 2.87 4.61 2.77 2.38
## SLC25A43 4.08 7.37 6.30 5.70 4.71 5.40 4.73
## UBE2A 96.86 96.42 93.37 94.93 115.63 103.18 89.39
## FGFR1 13.76 34.37 23.28 30.59 25.83 22.84 18.42
## FKBP6 0.07 0.01 0.04 0.00 0.05 0.02 0.03
## GTF2I 30.27 73.22 55.38 60.74 54.17 52.09 46.20
## SMC1B 1.06 0.38 0.31 0.35 0.43 0.20 0.81
## FBLN1 2.44 11.44 6.33 6.49 3.70 6.57 4.16
## ITGA8 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## CST7 54.19 100.49 93.03 84.74 61.53 97.00 53.04
## MAP2 0.01 0.01 0.07 0.00 0.04 0.01 0.03
## PIAS2 2.77 4.70 4.07 3.96 3.71 3.37 2.93
## AMPH 0.00 0.01 0.01 0.02 0.00 0.00 0.01
## ARAF 76.51 99.23 64.02 78.05 80.28 75.84 76.74
## MCCC1 6.78 11.36 9.92 9.39 7.88 8.66 8.46
## LAMP3 1.27 0.62 0.54 0.42 0.97 0.51 0.71
## FAP 0.04 0.00 0.00 0.00 0.05 0.00 0.00
## NEBL 1.91 4.16 4.83 3.59 2.24 2.65 2.24
## ACER3 9.17 13.48 11.89 14.67 15.90 10.98 9.50
## UBE2K 50.94 47.81 48.67 52.49 70.04 50.65 48.95
## PIK3C3 12.74 13.35 10.45 10.36 12.01 8.39 9.06
## N4BP2 1.75 2.07 2.06 1.63 2.57 1.41 1.22
## C12orf5 33.44 28.18 25.44 24.09 34.56 26.67 23.65
## TULP3 10.79 14.49 11.88 13.55 17.61 11.56 11.67
## SYNJ2 12.36 14.76 11.25 15.18 16.73 14.20 9.73
## ADCY2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PPP2R5C 92.91 100.38 89.01 100.22 105.42 99.25 96.65
## RBFOX1 0.03 0.00 0.01 0.00 0.00 0.00 0.00
## GNB1 122.59 178.14 127.52 173.35 178.51 141.79 132.60
## HOXA9 33.13 42.02 35.82 37.94 42.81 39.20 34.92
## EDN1 0.82 1.35 1.37 1.41 1.97 1.05 1.05
## MLLT10 8.32 9.93 9.80 10.00 12.86 7.55 7.78
## ZCWPW1 2.51 3.34 2.54 3.04 3.08 2.55 3.57
## ADCYAP1R1 0.04 0.01 0.00 0.00 0.00 0.00 0.00
## FGF20 0.08 0.01 0.03 0.02 0.00 0.00 0.14
## P2RY10 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ITM2A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NRD1 38.07 50.14 41.03 46.44 64.95 41.67 47.32
## VDAC3 135.13 158.36 150.99 151.38 162.55 150.50 139.51
## PCM1 32.81 38.55 27.03 31.64 41.35 31.16 35.27
## TNRC6C 1.34 1.93 1.00 1.56 2.75 1.04 1.19
## CBFA2T2 1.79 2.33 1.59 2.12 3.54 1.55 2.36
## BRINP1 0.00 0.01 0.00 0.00 0.00 0.00 0.01
## ITCH 8.54 13.03 10.42 11.97 16.85 9.12 8.50
## PKD2L2 0.03 0.00 0.00 0.07 0.01 0.00 0.01
## TP53INP2 1.21 1.71 1.02 1.18 1.58 1.09 0.90
## SDF4 104.77 144.66 100.30 120.37 134.65 123.27 110.38
## MYH7B 0.53 14.23 9.70 5.59 0.84 8.30 2.37
## BPIFB2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TP73 0.08 0.69 0.46 0.24 0.08 0.29 0.16
## TOLLIP 33.73 30.29 23.64 33.03 40.13 36.76 34.86
## UBE2D4 29.17 37.95 30.60 40.12 40.70 35.69 30.91
## CLUL1 0.05 0.03 0.01 0.03 0.22 0.00 0.20
## RUNX1T1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CDH17 0.02 0.89 0.59 0.23 0.14 0.47 0.09
## THOC1 9.13 15.00 12.12 13.03 14.99 14.74 12.68
## FKBP7 3.49 5.72 6.52 6.66 6.54 5.93 5.71
## OSBPL6 0.52 0.85 0.91 0.76 0.66 0.54 0.60
## SLC1A3 0.10 0.00 0.00 0.00 0.00 0.00 0.05
## XRCC5 150.02 249.62 200.38 219.31 211.85 189.88 168.33
## LXN 0.02 0.00 0.00 0.00 0.04 0.02 0.00
## SP140 0.72 0.10 0.00 0.16 0.39 0.04 0.14
## MKNK1 15.28 14.99 14.56 15.30 18.36 14.26 15.13
## TNS1 0.09 0.13 0.33 0.11 0.10 0.06 0.03
## REXO1 12.13 15.39 8.25 13.75 15.83 11.09 11.75
## SAR1A 77.64 65.78 61.39 61.88 84.90 55.85 61.97
## CDC14A 3.77 3.59 2.63 3.05 4.90 2.69 2.68
## RAPGEF3 1.33 1.46 1.39 1.58 2.24 1.56 1.64
## CEACAM1 1.08 2.85 2.32 2.30 3.42 1.91 1.73
## SENP1 12.32 12.87 11.05 12.69 15.33 9.75 9.02
## DUSP13 0.02 0.20 0.24 0.16 0.15 0.29 0.20
## CIC 4.38 10.40 6.76 9.21 9.93 7.20 7.53
## LIPE 4.10 3.79 2.59 3.99 3.40 3.02 2.45
## FDFT1 94.20 87.76 69.63 100.60 152.85 83.70 107.35
## PAFAH1B3 43.43 110.53 111.22 97.34 70.60 114.79 72.74
## OPHN1 1.86 1.75 1.65 2.37 1.35 1.51 1.39
## AFM 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## KIF22 50.25 55.27 51.35 49.48 50.52 49.65 49.17
## SCGN 0.02 0.00 0.00 0.00 0.00 0.00 0.03
## LRRC16A 2.26 5.39 3.70 3.98 3.55 3.27 3.33
## PGM1 13.91 28.23 20.44 23.38 20.61 22.32 20.79
## DDX1 49.95 89.31 70.33 75.29 75.45 67.74 61.56
## DNM2 38.60 61.11 44.96 64.58 63.03 48.54 46.15
## EPB41L2 9.77 12.97 11.99 14.40 13.23 10.61 9.09
## RIMS1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MOXD1 0.11 0.09 0.18 0.06 0.11 0.03 0.04
## STX7 10.27 10.66 9.91 9.82 11.86 8.86 8.98
## RABL2B 16.69 18.58 15.80 15.90 15.66 14.74 17.25
## KEAP1 44.24 81.52 55.17 63.27 67.00 58.00 47.68
## DDX43 0.02 0.00 0.00 0.00 0.00 0.00 0.00
## PTPRH 1.24 1.90 1.37 1.63 2.14 1.21 1.25
## DCT 0.13 0.02 0.01 0.04 0.00 0.04 0.04
## SLC35C2 57.21 61.66 40.44 55.90 57.04 50.79 50.80
## CRYBG3 4.85 5.36 4.57 5.57 8.47 4.76 5.55
## EPHA6 0.02 0.00 0.00 0.00 0.00 0.00 0.00
## SCTR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RFX3 0.49 0.89 0.87 0.70 0.71 0.69 0.55
## RIF1 4.06 8.07 6.67 6.95 7.39 5.29 3.81
## RAB21 26.20 25.11 18.53 23.92 33.65 22.23 19.11
## SLC4A4 0.01 0.00 0.00 0.01 0.00 0.00 0.00
## SMARCA2 23.50 23.10 18.73 18.04 24.20 19.79 21.53
## RDH8 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SESN1 3.11 2.81 2.73 2.69 4.08 2.26 2.72
## MID2 2.23 1.83 1.51 1.58 2.06 1.18 1.31
## PIH1D3 0.08 0.00 0.00 0.00 0.02 0.00 0.03
## COL5A3 0.02 0.06 0.05 0.02 0.04 0.06 0.02
## SRCAP 6.04 12.31 8.42 12.42 13.86 6.75 6.31
## KIAA0020 64.13 49.31 45.27 46.50 56.06 47.74 51.46
## CPB2 0.03 0.00 0.00 0.00 0.01 0.00 0.00
## CHRNA3 0.53 0.37 0.10 0.67 0.33 0.09 0.09
## KCNN2 0.00 0.03 0.00 0.04 0.00 0.00 0.00
## CNOT4 4.80 6.32 4.83 6.30 9.10 5.69 4.86
## PSEN1 16.11 18.11 13.99 15.10 25.68 11.68 12.65
## CPOX 9.57 12.79 12.04 12.55 15.82 12.74 10.74
## CLDND1 32.77 18.71 19.22 18.73 23.72 19.49 25.48
## MOK 7.20 5.07 4.62 7.21 7.19 6.01 6.87
## HSP90AA1 1348.57 1054.17 762.73 1096.52 1696.33 867.80 1116.78
## RBL1 7.62 9.43 7.79 9.33 10.00 7.02 6.33
## DLGAP4 21.81 28.27 18.58 24.03 24.78 19.90 20.22
## IGSF9B 0.60 1.06 0.86 0.69 0.61 0.42 0.42
## CFHR2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NDC80 6.18 18.47 15.11 12.83 8.92 14.60 8.95
## AP4E1 3.34 4.51 3.36 3.54 4.43 2.91 2.83
## RSBN1 1.75 2.74 1.25 2.32 3.98 1.27 2.04
## MAGI3 4.41 3.50 2.92 3.84 5.58 2.89 3.29
## CXCL2 0.81 0.25 1.44 0.23 0.61 0.39 0.41
## AFP 0.00 0.01 0.01 0.00 0.00 0.01 0.00
## COL4A4 0.03 0.01 0.02 0.01 0.03 0.01 0.02
## TCF7 6.93 18.16 12.16 14.90 13.05 11.26 8.19
## OSTM1 12.03 12.37 7.93 11.63 22.63 9.08 10.94
## CDH7 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## IMPG2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PCNP 78.07 86.18 88.79 90.70 111.47 87.33 85.64
## EXD2 7.79 13.03 8.87 9.24 12.93 7.66 8.46
## ARG2 13.62 26.53 23.15 14.59 11.80 17.56 12.76
## MEF2C 0.01 0.01 0.00 0.00 0.00 0.00 0.00
## PTPRC 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CACNA1S 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PKP1 0.09 0.29 0.25 0.21 0.08 0.26 0.08
## UBA5 33.38 31.06 25.08 27.96 35.44 24.38 26.94
## STK17B 1.66 1.01 0.35 0.95 2.38 0.64 0.67
## CDC14B 4.71 6.83 5.15 6.19 5.65 4.29 4.63
## ZNF510 3.18 2.87 2.54 2.52 2.55 1.86 1.62
## LRP2 0.00 0.00 0.00 0.01 0.00 0.00 0.00
## ZNF506 14.14 7.50 7.60 6.65 10.37 6.64 9.63
## JMJD4 17.77 24.86 20.89 18.09 12.64 20.93 14.73
## DUSP12 45.48 42.01 38.52 41.19 44.06 40.97 43.36
## AACS 7.31 14.46 8.80 11.83 11.16 10.39 10.23
## KIAA0141 15.21 14.88 14.41 13.93 13.29 13.60 12.65
## SLC13A1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CADPS2 2.66 9.73 6.73 5.85 3.21 6.47 4.86
## PCDHB4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PCDHA6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PCDHGA2 0.02 0.03 0.03 0.00 0.05 0.04 0.00
## HSPB11 75.90 108.22 150.04 105.80 97.65 139.79 108.10
## PHLPP1 0.70 1.92 1.22 1.69 1.49 1.24 0.94
## ATP8B1 0.77 1.06 0.83 1.24 1.35 0.74 0.76
## IL12RB2 0.03 0.08 0.03 0.03 0.06 0.03 0.09
## SMARCD3 5.19 5.94 5.51 5.98 4.83 5.64 6.06
## WDR70 24.05 38.82 30.94 27.77 32.14 33.75 35.06
## FYB 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## MPP4 0.01 0.02 0.01 0.00 0.01 0.01 0.01
## STRADB 28.08 17.47 16.09 23.21 24.80 21.18 21.82
## BZW1 172.38 149.56 123.51 153.84 219.12 141.82 124.43
## PGR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## C1QTNF3 0.27 0.83 0.77 0.51 0.50 0.71 0.63
## ME2 8.69 8.81 9.53 9.00 11.32 8.76 8.26
## C5orf22 19.93 16.76 14.13 18.68 25.74 14.87 15.25
## CCNT2 2.21 2.87 3.29 3.80 4.17 2.73 2.40
## FAM135A 1.26 1.99 2.58 2.13 1.98 2.58 1.22
## COL19A1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## EPB41L3 0.00 0.00 0.00 0.02 0.00 0.05 0.00
## COBLL1 3.14 1.97 1.18 2.05 2.38 1.14 1.52
## DLG3 15.17 25.47 20.44 17.83 17.85 13.65 11.71
## KCNK2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SERTAD4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TRAF5 6.43 17.66 16.42 16.20 13.12 14.78 10.82
## MRPL22 91.30 88.35 100.70 85.84 87.11 99.66 89.54
## GEMIN5 6.63 10.24 6.95 8.92 11.02 6.50 5.95
## OPRK1 0.03 0.02 0.00 0.02 0.02 0.00 0.01
## NFE2L1 34.83 45.40 31.84 41.34 53.60 28.38 26.96
## SEMA5B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GSK3B 16.58 22.94 15.86 15.54 17.99 15.59 16.35
## ITGB5 21.02 38.10 26.10 36.61 48.26 24.10 27.69
## ERC1 2.14 4.35 2.66 3.96 3.44 2.09 2.11
## XPO1 27.89 70.23 56.98 55.83 62.49 56.15 45.28
## C4orf6 0.03 0.05 0.00 0.00 0.00 0.00 0.00
## RNF13 21.71 29.42 30.39 24.14 36.59 28.67 24.43
## TRPM3 0.00 0.00 0.06 0.00 0.00 0.00 0.00
## PALB2 7.89 14.44 13.20 11.19 12.29 13.42 10.29
## DOPEY1 1.10 1.82 1.87 1.76 2.02 1.58 1.61
## LYRM2 54.58 49.19 53.31 46.41 48.31 48.03 46.29
## BCKDHB 12.62 14.81 12.92 12.84 12.12 12.89 13.94
## mRNA_R38 mRNA_R42 mRNA_R41 mRNA_R40 mRNA_R39 mRNA_R37 mRNA_R36
## TSPAN6 20.80 19.63 24.60 12.37 18.25 21.11 17.54
## TNMD 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DPM1 185.06 135.75 173.80 188.45 173.70 179.63 143.49
## SCYL3 1.75 1.41 1.76 0.84 1.54 2.35 1.83
## C1orf112 7.92 5.50 8.55 4.33 5.73 5.16 7.34
## FGR 0.05 0.06 0.17 0.04 0.04 0.08 0.06
## CFH 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## FUCA2 75.88 70.61 79.88 41.59 62.92 56.30 66.46
## GCLC 16.20 15.95 16.64 17.84 30.51 45.63 34.25
## NFYA 12.98 4.98 8.20 2.46 9.51 17.38 7.01
## STPG1 4.08 2.72 2.40 1.52 3.83 5.67 3.38
## NIPAL3 5.85 7.82 8.57 2.99 5.41 7.81 6.45
## LAS1L 80.92 60.37 74.25 39.39 67.58 62.53 75.61
## ENPP4 4.03 2.62 5.80 2.62 4.38 5.02 3.95
## SEMA3F 1.74 6.32 6.19 0.91 1.70 2.29 2.30
## CFTR 0.00 0.01 0.00 0.00 0.00 0.01 0.00
## ANKIB1 16.23 9.13 16.31 5.42 15.81 17.02 14.06
## CYP51A1 62.23 35.87 46.62 42.66 50.11 78.18 56.19
## KRIT1 23.96 16.68 28.11 10.76 23.01 24.42 20.56
## RAD52 7.17 5.73 6.85 2.42 6.60 5.92 5.24
## BAD 37.83 58.17 46.86 48.38 38.00 29.11 48.47
## LAP3 35.50 25.35 29.13 23.86 22.74 42.89 31.18
## CD99 71.70 79.40 76.24 105.99 74.13 81.21 80.69
## HS3ST1 1.17 0.72 1.04 0.19 0.96 1.00 0.83
## AOC1 21.03 25.34 31.17 6.83 19.95 21.22 20.16
## WNT16 0.62 1.22 1.79 0.17 0.70 0.49 0.76
## HECW1 6.68 4.47 5.74 11.33 7.55 7.14 5.99
## MAD1L1 155.00 82.03 65.71 196.12 159.10 220.67 141.69
## LASP1 124.88 127.93 184.74 82.53 146.26 141.65 165.48
## SNX11 16.17 14.33 12.39 15.69 14.66 20.31 16.17
## TMEM176A 4.62 8.55 5.85 4.58 5.43 4.96 5.39
## M6PR 145.10 100.27 116.76 81.50 120.80 173.86 124.19
## KLHL13 0.10 0.09 0.21 0.02 0.10 0.12 0.06
## CYP26B1 0.04 0.37 0.22 0.07 0.14 0.23 0.25
## ICA1 19.40 32.24 36.09 27.27 26.80 25.63 29.52
## DBNDD1 2.39 8.95 7.64 1.21 4.14 3.20 4.97
## ALS2 15.98 5.20 9.81 7.40 15.29 22.26 12.08
## CASP10 0.47 0.68 0.65 0.17 0.31 0.39 0.40
## CFLAR 19.62 13.84 13.63 14.53 18.19 29.51 13.99
## TFPI 0.12 0.02 0.15 0.10 0.09 0.36 0.03
## NDUFAF7 14.65 14.30 17.44 7.99 14.27 11.97 14.44
## RBM5 31.84 24.55 29.97 16.61 31.62 33.31 31.54
## MTMR7 0.76 0.56 0.54 1.00 1.01 0.64 0.92
## SLC7A2 2.01 2.17 3.12 0.86 1.90 1.70 2.05
## ARF5 199.15 200.30 200.31 268.61 217.82 195.80 203.06
## SARM1 3.26 3.21 3.65 0.26 3.78 5.15 4.56
## POLDIP2 133.31 108.01 122.81 94.92 129.11 133.77 142.60
## PLXND1 23.89 31.59 35.93 31.07 30.87 17.95 33.50
## AK2 176.76 155.89 191.62 105.26 140.65 134.87 161.10
## CD38 0.03 0.06 0.01 0.00 0.00 0.00 0.00
## FKBP4 204.82 181.39 182.17 117.35 142.69 232.45 163.25
## KDM1A 50.63 44.95 57.04 22.98 38.36 43.68 44.17
## RBM6 40.27 38.78 40.19 40.50 39.45 38.69 41.02
## CAMKK1 3.47 4.21 4.21 3.91 4.62 3.49 5.15
## RECQL 43.30 24.69 41.72 22.74 37.27 51.88 39.08
## CCDC132 13.30 7.75 12.23 7.62 10.65 11.38 10.71
## HSPB6 0.05 0.24 0.07 0.05 0.16 0.24 0.06
## ARHGAP33 3.09 1.37 3.09 1.54 5.55 3.18 3.76
## NDUFAB1 174.91 200.23 141.32 256.29 153.89 164.37 164.74
## PDK4 0.31 0.58 0.56 0.20 0.26 0.26 0.26
## SLC22A16 0.03 0.09 0.00 0.19 0.06 0.07 0.04
## ZMYND10 0.39 0.55 1.01 0.70 0.82 0.26 0.67
## ABCB5 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## ARX 0.18 0.18 0.21 0.08 0.15 0.28 0.18
## SLC25A13 34.81 30.18 40.10 19.60 29.93 30.51 34.67
## ST7 26.24 26.61 29.38 13.02 22.19 20.05 24.25
## CDC27 20.11 18.24 23.28 9.60 19.13 19.14 18.32
## SLC4A1 0.01 0.01 0.00 0.02 0.03 0.01 0.13
## CALCR 0.01 0.00 0.04 0.01 0.00 0.02 0.00
## HCCS 75.48 52.82 54.20 43.99 50.67 85.76 57.07
## DVL2 25.47 20.13 26.40 10.77 25.05 33.93 25.69
## PRSS22 8.09 15.97 16.32 9.30 12.88 9.08 19.84
## UPF1 35.84 27.61 33.15 17.24 30.17 33.24 29.43
## SKAP2 7.32 6.81 13.43 5.72 9.58 10.89 13.27
## SLC25A5 615.93 683.91 615.95 448.93 473.19 539.53 614.43
## CCDC109B 19.36 16.79 19.93 11.37 18.10 17.91 18.93
## HOXA11 10.68 10.61 10.45 5.99 7.97 9.97 9.80
## POLR2J 350.92 334.71 368.49 260.89 408.80 305.00 380.37
## DHX33 19.98 11.68 17.50 6.50 16.78 18.85 16.18
## MEOX1 0.00 0.01 0.01 0.00 0.00 0.00 0.03
## THSD7A 0.56 0.07 0.21 0.15 0.54 1.90 0.32
## LIG3 14.62 10.97 12.05 3.85 10.44 15.73 11.81
## RPAP3 33.88 30.49 39.94 19.07 26.44 28.99 26.37
## ACSM3 0.71 0.36 0.90 1.37 0.86 1.47 0.76
## AC004381.6 10.64 5.28 8.08 3.98 7.13 9.48 7.90
## CIAPIN1 44.51 47.70 43.69 30.45 36.91 43.84 49.71
## FAM214B 6.24 4.63 4.36 5.92 6.90 11.57 6.09
## COPZ2 28.37 26.66 23.56 31.88 23.99 20.64 25.46
## PRKAR2B 5.50 1.59 3.47 1.31 4.36 5.91 3.80
## MSL3 11.58 14.32 17.81 13.07 12.16 12.07 14.58
## CREBBP 4.02 5.44 4.93 2.40 4.10 4.12 4.18
## BZRAP1 2.20 4.43 5.74 0.79 3.08 2.17 2.59
## MPO 0.04 0.01 0.02 0.00 0.00 0.01 0.01
## PON1 0.00 0.06 0.13 0.11 0.14 0.03 0.07
## GCFC2 27.58 23.15 24.13 24.62 23.64 22.26 18.80
## WDR54 19.90 31.25 28.56 15.40 22.06 18.19 27.15
## CROT 12.08 6.14 9.84 8.34 12.87 11.19 9.78
## ABCB4 0.38 0.70 0.71 0.43 0.35 0.05 0.05
## KMT2E 12.97 8.48 13.98 4.19 16.12 19.36 12.19
## RHBDD2 78.60 100.30 79.62 72.20 81.94 91.47 87.05
## SOX8 0.05 0.55 0.38 0.25 0.18 0.09 0.16
## IBTK 15.28 8.46 13.68 17.00 18.25 16.81 13.68
## ZNF195 26.90 17.90 26.94 12.60 27.33 24.77 24.36
## MYCBP2 7.09 7.57 10.48 2.04 6.91 5.74 7.69
## FBXL3 17.92 15.75 24.14 12.40 18.45 26.13 21.52
## ITGAL 0.00 0.01 0.00 0.01 0.00 0.00 0.01
## PDK2 11.12 18.32 19.17 8.21 12.17 14.72 17.77
## ITGA3 130.43 129.15 150.72 111.10 141.12 105.23 158.66
## ZFX 4.78 5.46 6.16 1.82 4.70 6.28 4.16
## LAMP2 57.16 35.04 56.95 29.54 57.44 80.20 55.29
## GGNBP2 43.36 35.06 39.69 30.12 47.50 47.41 41.34
## ITGA2B 0.41 0.07 0.40 0.32 0.11 0.14 0.42
## ASB4 5.83 8.79 10.75 1.41 4.01 2.76 4.74
## GDE1 41.56 44.57 46.43 21.18 37.66 39.03 42.52
## C19orf60 73.89 87.25 77.34 109.02 73.34 68.99 80.74
## CRLF1 5.19 7.26 5.72 5.99 5.67 5.74 5.52
## OSBPL7 7.09 4.69 6.36 2.79 7.35 5.70 5.78
## TMEM98 29.35 23.40 27.06 17.35 22.41 26.02 23.79
## YBX2 5.58 9.26 11.51 4.25 7.51 4.52 7.63
## KRT33A 0.02 0.02 0.00 0.00 0.00 0.00 0.00
## ABCC8 0.85 0.64 0.98 0.44 0.73 0.70 0.67
## CCL18 0.09 0.00 0.05 0.00 0.05 0.36 0.00
## CCL3 0.00 0.00 0.00 0.00 0.00 0.04 0.00
## SYNRG 7.09 6.02 6.86 2.92 6.22 10.71 5.60
## CACNG3 0.01 0.00 0.00 0.00 0.00 0.00 0.00
## TMEM132A 68.85 58.57 55.75 31.80 49.31 48.58 42.87
## AP2B1 57.39 43.88 55.29 31.06 48.76 71.13 59.99
## TAC1 0.00 0.00 0.00 0.00 0.00 0.03 0.00
## ZNF263 16.42 14.06 16.56 12.76 16.10 21.80 20.87
## CX3CL1 4.04 1.90 2.36 1.82 2.96 4.22 2.72
## SPATA20 35.78 33.33 43.14 17.98 39.52 34.27 39.66
## CACNA1G 0.03 0.16 0.04 0.03 0.04 0.14 0.08
## TNFRSF12A 463.65 366.54 400.90 310.79 480.08 448.27 443.25
## DLX6 0.84 0.65 1.00 0.13 0.95 1.46 0.78
## MAP3K9 4.04 3.46 2.78 2.48 3.85 6.00 3.33
## RALA 58.00 51.42 63.05 42.01 58.32 53.82 55.53
## BAIAP2L1 48.88 27.42 33.80 26.35 41.31 58.27 41.14
## KDM7A 1.02 2.69 3.70 1.23 1.88 1.63 2.26
## ETV1 1.93 1.97 4.46 1.11 2.29 4.40 2.96
## AGK 27.56 13.66 25.17 6.52 21.97 31.38 21.74
## ALDH3B1 11.17 13.31 17.77 8.98 15.59 12.50 17.52
## TTC22 1.00 0.84 1.39 0.42 1.20 1.39 1.09
## PHTF2 21.05 12.77 24.06 9.78 16.85 17.18 17.51
## CCL26 0.83 4.12 1.51 5.78 1.21 1.29 0.92
## FARP2 6.16 4.49 4.27 2.58 4.86 7.40 6.36
## USH1C 6.55 15.05 13.46 7.54 9.21 5.57 11.25
## GGCT 245.96 197.94 227.29 301.20 224.76 188.67 213.14
## DBF4 80.88 52.11 92.93 26.41 71.73 66.92 64.90
## TBXA2R 0.62 0.30 0.30 0.47 0.57 0.43 0.34
## IFRD1 70.45 59.41 66.75 96.93 70.88 68.31 82.53
## LGALS14 0.15 0.09 0.08 0.20 0.09 0.70 0.25
## COX10 13.19 7.90 11.95 5.36 13.54 17.63 12.92
## GTF2IRD1 29.05 66.15 63.93 66.59 48.30 24.57 57.00
## PAF1 44.51 63.93 62.99 20.07 37.60 31.13 41.68
## VPS41 13.75 10.36 13.55 7.88 13.32 18.29 12.61
## ARHGAP44 2.16 2.42 2.87 0.77 2.04 1.77 2.43
## ELAC2 61.48 60.72 68.62 31.94 58.72 52.55 62.42
## SCIN 0.17 0.08 0.06 0.09 0.21 0.38 0.09
## ARSD 23.09 16.91 17.67 12.45 19.10 25.95 20.70
## PNPLA4 30.45 26.17 26.91 30.55 33.34 41.79 34.05
## MYH13 0.00 0.00 0.01 0.00 0.00 0.01 0.00
## ADIPOR2 33.37 28.04 36.56 15.91 30.69 38.31 33.43
## CDKL3 1.35 1.48 1.36 3.41 1.90 1.48 1.75
## UPP2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PRSS21 0.00 0.00 0.00 0.07 0.00 0.00 0.00
## MARK4 4.11 5.86 6.93 1.56 5.32 4.18 4.56
## PROM1 0.08 0.08 0.27 0.01 0.01 0.03 0.09
## CCDC124 124.28 140.70 143.49 127.52 129.17 110.76 143.94
## CEACAM21 1.70 3.18 3.20 4.92 2.54 3.89 3.97
## PAFAH1B1 60.87 62.18 58.21 55.27 55.21 70.82 61.07
## NOS2 0.31 0.26 0.28 0.02 0.19 0.33 0.10
## DNAH9 0.03 0.17 0.15 0.01 0.03 0.08 0.11
## KIAA0100 31.65 45.03 50.98 12.72 25.54 24.31 38.41
## SLC13A2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GAS7 0.34 0.43 0.43 0.06 0.38 0.81 0.59
## TRAPPC6A 37.53 43.75 34.26 53.96 41.36 53.44 41.24
## MATK 1.67 0.30 0.62 0.80 2.18 5.68 0.65
## CEACAM7 0.00 0.00 0.00 0.00 0.00 0.03 0.00
## CD79B 0.16 0.04 0.00 0.04 0.00 0.05 0.00
## SCN4A 0.05 0.27 0.14 0.07 0.09 0.12 0.22
## ST7L 19.94 13.21 16.40 7.17 13.08 14.04 12.99
## TKTL1 0.29 0.18 0.18 0.16 0.38 0.89 0.20
## PAX6 16.65 12.27 18.25 7.18 21.42 23.64 19.13
## RPUSD1 39.92 54.82 48.46 23.16 38.13 24.80 45.74
## RHBDF1 21.67 11.35 13.89 21.06 26.26 32.36 18.87
## LUC7L 20.82 27.31 32.69 17.71 19.27 10.99 20.84
## CACNA2D2 0.86 1.56 1.85 0.43 1.41 1.19 1.36
## BAIAP3 1.98 1.47 1.98 1.27 2.04 2.68 2.17
## TSR3 79.76 85.56 69.10 91.69 68.84 64.10 84.67
## PIGQ 18.57 30.04 27.42 15.83 19.08 10.32 24.24
## CRAMP1L 6.26 4.16 5.34 1.70 5.39 5.28 4.46
## TEAD3 6.10 5.98 7.55 1.98 5.85 5.55 6.25
## SELE 0.00 0.00 0.00 0.00 0.00 0.03 0.00
## DNAJC11 34.77 32.08 38.64 16.96 30.46 34.05 37.02
## FMO3 0.00 0.00 0.04 0.03 0.01 0.05 0.07
## MYLIP 4.66 3.53 5.31 2.15 4.82 7.74 4.31
## NOX1 0.06 0.04 0.10 0.25 0.10 0.17 0.15
## E2F2 4.40 4.32 5.52 1.47 3.79 3.51 4.20
## PSMB1 287.87 314.90 264.87 459.29 280.84 269.46 284.77
## SYN1 1.26 1.35 1.71 0.45 1.36 1.37 1.22
## JARID2 8.99 5.24 7.29 3.01 8.31 10.44 7.56
## CDKL5 0.14 0.22 0.26 0.03 0.17 0.37 0.09
## CAMK1G 0.07 0.03 0.01 0.01 0.12 0.41 0.08
## CDK11A 28.38 22.34 32.72 21.23 34.25 29.62 26.91
## NADK 32.58 39.13 41.79 24.90 38.37 29.54 38.84
## TFAP2B 0.00 0.08 0.00 0.00 0.00 0.00 0.00
## TFAP2D 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DLEC1 0.52 0.38 0.75 0.37 0.86 0.52 0.65
## CYTH3 9.01 9.59 13.34 7.13 12.54 9.04 13.95
## ADAM22 2.12 2.37 3.58 0.80 2.17 2.02 2.10
## SYPL1 128.33 87.59 141.26 94.42 132.58 160.86 116.56
## CYB561 31.15 24.81 27.55 19.64 28.68 31.32 30.27
## SPAG9 26.70 15.90 21.16 10.07 24.18 28.64 22.30
## CELSR3 12.63 10.99 15.26 7.04 13.24 10.06 12.82
## AASS 2.77 2.00 3.44 0.67 3.23 3.36 2.93
## PLEKHG6 0.64 1.46 0.81 0.85 0.92 1.08 1.58
## SS18L2 47.64 55.82 51.25 56.72 45.14 33.43 45.37
## MPND 12.61 20.12 17.50 14.03 9.98 8.99 14.05
## MGST1 29.03 19.20 31.76 18.01 19.54 25.87 21.03
## CRY1 7.63 4.61 7.67 3.20 7.47 10.54 6.52
## PGLYRP1 0.18 0.09 0.00 0.00 0.37 0.48 0.06
## NFIX 7.17 7.58 8.32 2.51 7.80 10.88 9.09
## ST3GAL1 5.13 4.22 4.08 1.55 4.41 3.78 3.64
## MMP25 0.20 0.27 0.16 0.41 0.32 0.46 0.34
## IL32 29.36 9.56 12.06 14.76 20.79 39.26 14.47
## PKD1 19.68 10.27 14.34 7.26 22.39 18.78 21.93
## MAPK8IP2 2.28 3.11 3.10 2.81 2.72 2.51 4.14
## MED24 56.60 51.99 59.17 39.63 54.62 44.00 61.08
## RHOBTB2 7.81 7.40 8.36 3.59 7.64 8.39 9.28
## HEATR5B 2.98 2.25 3.31 1.28 3.72 2.91 3.17
## SEC62 136.17 95.42 138.59 115.85 129.26 135.00 106.98
## RPS20 2134.99 2385.04 1924.81 3011.22 2333.86 2141.48 2099.08
## CSDE1 129.01 89.64 134.54 48.63 104.36 139.67 114.53
## UBE3C 44.08 31.93 43.93 14.62 38.13 51.07 39.50
## REV3L 3.56 2.77 3.97 1.81 3.41 3.50 3.02
## TENM1 0.01 0.01 0.02 0.00 0.01 0.02 0.02
## PAX7 0.00 0.01 0.00 0.00 0.00 0.03 0.00
## MASP2 0.38 0.46 0.53 0.09 0.43 0.44 0.45
## IYD 0.04 0.00 0.01 0.01 0.12 0.01 0.06
## FAM76A 3.91 3.25 4.97 1.58 4.75 6.12 4.03
## TRAF3IP3 2.14 1.70 2.61 1.61 2.57 2.87 2.43
## POMT2 15.18 13.82 16.66 6.52 16.44 11.73 15.82
## VTA1 28.82 16.60 24.95 14.46 25.36 28.88 23.76
## MLXIPL 4.19 5.73 7.99 3.70 8.07 5.83 7.44
## BAZ1B 40.43 31.41 47.08 11.78 35.56 33.48 36.99
## RANBP9 19.10 17.97 28.14 8.97 19.33 18.40 23.76
## ETV7 2.17 2.36 2.82 0.90 2.06 1.84 2.68
## SPRTN 5.69 4.26 5.64 2.65 6.16 5.96 5.80
## METTL13 26.98 23.90 24.44 17.21 20.59 27.65 23.15
## DYRK4 38.98 30.50 30.57 29.08 41.17 42.63 35.51
## ZNF207 155.59 110.74 147.65 51.48 121.68 139.32 127.31
## UQCRC1 172.40 251.27 228.15 207.85 167.99 140.04 220.51
## STARD3NL 44.09 39.69 49.53 21.69 36.39 34.51 39.72
## CD9 740.71 631.99 723.95 561.76 805.99 681.23 739.31
## HHATL 0.24 0.00 0.06 0.04 0.06 0.27 0.00
## NCAPD2 25.93 26.59 42.70 7.25 21.43 20.95 25.44
## IFFO1 0.13 0.08 0.19 0.22 0.11 0.20 0.17
## GIPR 1.87 1.83 2.37 1.11 2.72 1.78 2.26
## PHF7 8.44 10.31 12.23 7.20 11.74 13.47 10.40
## SEMA3G 0.07 0.14 0.16 0.02 0.06 0.06 0.08
## NISCH 16.39 8.11 13.66 6.50 16.70 17.36 15.69
## STAB1 0.17 0.24 0.23 0.14 0.03 0.19 0.19
## FUZ 0.45 1.31 1.26 0.73 0.61 1.05 0.53
## SLC6A13 0.22 0.15 0.03 0.83 0.43 0.40 0.05
## IDS 27.76 22.03 26.94 16.41 28.00 33.86 26.67
## PRSS3 26.21 52.62 36.79 22.61 23.18 18.87 28.54
## ZNF200 9.89 6.65 8.57 5.07 9.43 10.25 7.11
## CD4 0.31 0.29 0.47 0.07 0.54 1.07 0.37
## LRRC23 26.04 29.94 28.13 39.43 30.09 23.65 32.32
## BTK 0.00 0.00 0.04 0.01 0.00 0.01 0.00
## HFE 0.53 0.47 1.02 0.06 0.51 0.46 0.31
## SCMH1 13.27 13.17 14.71 4.80 11.47 6.92 11.37
## FYN 36.47 44.41 58.76 19.85 40.82 33.33 46.51
## HIVEP2 4.84 3.62 4.25 1.48 4.26 5.54 4.13
## FMO1 0.00 0.00 0.07 0.06 0.01 0.01 0.00
## TCEB3 38.30 22.00 28.89 14.89 31.56 42.86 29.70
## LYPLA2 50.25 61.12 57.80 48.43 52.72 52.64 59.97
## CLCN6 2.85 1.54 2.14 1.05 2.87 3.66 2.65
## MRC2 2.03 3.63 3.84 1.20 1.86 2.55 2.21
## NME2 821.12 926.13 733.47 1060.54 893.53 833.54 752.58
## SLC6A7 0.05 0.01 0.01 0.00 0.01 0.04 0.00
## TSPAN9 12.14 11.01 11.07 5.79 10.36 9.55 10.85
## BTBD7 11.13 10.15 12.62 5.05 11.06 8.86 10.84
## APBA3 7.51 10.27 9.40 4.93 7.64 4.51 8.49
## MKS1 18.26 9.70 14.05 9.90 15.84 17.24 16.95
## ABHD5 16.53 11.47 15.39 7.74 17.05 19.88 16.53
## KAL1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## AKAP8L 18.64 19.13 20.42 24.41 20.88 32.24 20.82
## MBTD1 3.04 2.29 4.47 1.65 3.62 3.39 2.88
## UTP18 65.57 72.59 73.33 57.88 52.30 45.24 68.75
## RNF216 23.53 19.57 25.32 12.12 24.58 24.62 27.72
## TTC19 53.18 41.63 44.75 29.94 39.34 57.04 40.14
## PTBP1 190.51 141.50 183.96 107.43 185.16 157.13 197.22
## DPF1 5.33 4.29 6.44 4.28 5.08 6.25 7.04
## SYT7 7.17 6.70 8.51 2.22 6.55 8.55 7.28
## LARS2 13.75 9.90 12.80 5.74 10.97 13.78 13.02
## PIK3C2A 8.30 5.44 10.01 3.22 8.76 13.27 8.07
## PLAUR 223.96 99.79 85.71 109.88 127.36 199.18 110.39
## ANLN 56.06 32.90 76.62 20.77 49.67 33.11 41.39
## WIZ 22.20 15.39 20.00 4.31 20.10 23.12 20.30
## RABGAP1 4.81 4.84 8.44 3.12 6.24 5.90 5.93
## DCN 0.02 0.02 0.00 0.00 0.00 0.04 0.39
## QPCTL 8.96 18.69 14.31 12.79 10.67 7.90 14.54
## PPP5C 78.41 69.15 101.20 28.77 71.47 61.71 74.26
## CEP68 7.17 5.47 5.97 3.41 7.14 10.45 6.94
## MAP4K3 7.39 3.90 8.73 4.38 8.08 9.01 6.95
## ZBTB32 0.43 0.92 0.40 0.08 0.89 0.52 0.32
## TYROBP 0.00 0.00 0.07 0.00 0.00 0.00 0.00
## TMEM159 5.99 6.88 6.51 14.28 8.43 12.48 10.15
## GABRA3 2.88 3.28 5.03 0.71 1.94 1.60 2.49
## BRCA1 26.73 17.64 24.18 10.98 18.81 17.81 22.46
## ERCC1 84.50 91.59 87.10 85.88 82.58 93.61 79.89
## CD22 5.67 3.41 3.77 2.69 9.41 13.08 7.56
## MBTPS2 16.13 8.82 13.85 6.39 11.68 17.87 11.67
## PRICKLE3 16.12 9.93 16.04 4.25 17.15 15.03 16.50
## LTF 0.11 0.14 0.09 0.12 0.34 0.22 0.09
## EXTL3 7.07 6.15 6.60 2.61 5.47 8.09 6.00
## NR1H4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ELOVL5 60.61 38.79 62.99 47.66 57.69 72.80 59.10
## ALOX5 0.00 0.01 0.01 0.00 0.00 0.04 0.00
## KDM5D 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CALCOCO1 18.70 29.89 32.30 5.81 17.20 21.55 19.98
## UBR7 37.57 28.20 43.01 14.84 29.89 28.48 35.24
## MAP4K5 10.25 6.42 13.91 4.73 9.95 9.58 9.79
## EHD3 0.00 0.01 0.01 0.00 0.00 0.00 0.01
## PSMC4 187.50 167.55 178.16 134.44 177.31 198.95 204.90
## MAN2B2 10.87 7.85 10.44 6.08 10.64 11.22 10.12
## SLC7A14 0.01 0.00 0.00 0.00 0.01 0.00 0.00
## CLDN11 20.42 27.73 47.33 12.59 18.60 19.27 23.13
## SLC25A39 229.87 242.58 261.65 160.57 208.68 193.33 253.46
## MVP 14.39 11.63 10.90 6.29 13.00 16.10 13.47
## NUB1 60.73 41.61 66.49 24.63 44.27 61.09 53.45
## PGM3 23.05 13.01 19.46 11.38 18.64 25.76 19.00
## RWDD2A 3.67 4.02 4.32 3.31 4.99 5.38 4.85
## CLK1 24.68 30.63 35.65 46.95 29.72 26.83 30.39
## POLR3B 3.41 2.16 3.44 1.44 2.88 3.10 3.13
## ANGEL1 13.53 9.06 11.59 4.65 12.47 22.66 12.03
## RNF14 49.90 23.03 29.87 37.04 42.86 75.31 38.64
## DNASE1L1 21.22 18.73 23.68 10.58 20.46 24.91 22.30
## DDX11 46.48 33.22 53.88 17.35 49.53 35.20 54.12
## HEBP1 47.35 47.96 52.01 60.60 53.15 50.45 56.83
## GPRC5A 101.75 76.46 89.76 16.16 71.00 75.15 62.72
## MAMLD1 6.57 4.17 5.25 3.05 8.66 6.35 7.91
## CD6 0.88 1.13 1.17 0.21 0.56 1.40 0.82
## TACC3 46.03 49.06 61.38 32.96 44.74 30.74 45.03
## UFL1 8.10 2.17 7.78 2.91 9.60 9.58 5.84
## POLA2 78.00 81.38 94.10 41.45 59.34 49.32 76.63
## ZC3H3 9.12 5.95 7.84 2.76 10.28 10.18 8.57
## CAPN1 103.18 124.78 134.41 71.44 110.57 91.01 130.19
## ACPP 0.02 0.00 0.02 0.00 0.00 0.02 0.00
## MDH1 149.29 164.36 158.27 157.80 146.73 135.14 151.46
## SLC30A9 20.39 18.56 31.78 15.37 22.10 20.17 23.87
## MTMR11 5.04 1.87 3.02 0.98 2.66 5.39 2.80
## COX15 24.79 16.11 23.09 9.17 18.88 23.27 21.45
## CCDC88C 9.02 6.33 7.53 4.90 8.52 7.21 6.93
## YAF2 7.87 7.42 10.35 5.13 6.91 8.62 8.94
## ZMYND11 6.85 4.16 7.27 2.77 6.64 5.63 6.34
## WAS 0.18 0.56 0.42 0.44 0.57 0.45 0.94
## DPEP1 0.94 7.77 6.19 0.83 1.33 0.88 3.11
## BID 41.02 50.75 45.33 47.96 42.06 39.53 51.50
## MATR3 259.21 176.15 283.43 106.44 206.56 230.07 228.87
## NPC1L1 0.03 0.04 0.04 0.03 0.03 0.04 0.02
## XYLT2 19.36 11.94 15.10 8.49 16.17 17.10 14.54
## RGPD5 4.68 2.60 3.05 0.98 4.36 6.08 6.40
## STMN4 0.00 0.05 0.00 0.03 0.02 0.00 0.00
## NUDCD3 32.60 34.42 35.97 34.16 31.47 36.18 38.49
## ISL1 0.58 0.38 0.60 0.19 0.71 0.52 0.47
## CHDH 8.79 9.52 10.99 2.32 7.93 7.82 9.45
## IL20RA 7.75 9.49 7.97 5.21 6.34 6.20 7.54
## CLCA1 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## CLCA4 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## GLT8D1 50.19 49.40 54.04 41.85 49.23 48.55 46.84
## ATP2C1 41.63 33.82 45.49 27.46 41.42 35.04 45.08
## SRCIN1 1.36 2.10 2.74 0.19 1.61 2.18 1.72
## IGF1 0.66 0.65 1.09 0.43 0.89 0.47 0.47
## SLC38A5 170.30 214.48 209.07 125.51 138.85 108.46 173.10
## MAGIX 1.49 2.78 1.72 0.99 1.50 0.97 1.28
## RALBP1 34.38 30.73 38.89 20.88 37.80 56.60 37.55
## RUFY3 5.27 3.09 5.59 2.86 6.02 6.75 4.61
## CNTN1 1.65 3.05 4.83 1.08 1.95 2.36 3.03
## SLC11A1 0.70 0.18 0.26 0.06 0.31 0.96 0.14
## WWTR1 31.09 17.48 22.01 11.98 21.20 29.73 24.73
## AGPS 15.47 9.88 18.48 5.65 13.83 13.66 13.65
## CXorf56 40.61 40.96 36.62 29.02 36.83 44.30 38.45
## ATP1A2 0.01 0.00 0.05 0.00 0.01 0.07 0.01
## TTC27 25.36 21.03 24.40 23.48 16.81 17.69 21.26
## ZNF582 0.16 0.02 0.02 0.29 0.31 0.57 0.05
## VSIG2 0.02 0.02 0.03 0.04 0.10 0.04 0.00
## PHLDB1 23.42 29.58 41.77 13.55 32.20 26.35 34.33
## MARCO 0.34 0.03 0.04 0.16 0.37 0.33 0.08
## CYP24A1 5.75 2.56 6.47 1.30 5.07 4.23 5.11
## PRDM11 2.01 2.24 2.57 0.27 1.62 1.97 2.63
## SYT13 0.88 0.35 0.50 0.13 0.47 1.06 0.36
## SNAI2 24.92 6.26 7.64 8.81 18.92 20.78 16.27
## CD74 53.56 43.91 45.79 23.12 52.65 56.60 41.80
## HGF 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## ZRANB1 4.53 5.15 7.03 2.75 4.34 4.23 5.61
## NCDN 17.15 10.18 12.96 3.41 13.06 19.87 14.25
## GPR124 0.11 0.17 0.13 0.01 0.11 0.14 0.16
## ZFP64 10.28 11.37 13.30 9.74 12.05 11.88 14.75
## MNAT1 56.76 42.80 45.95 50.23 44.48 52.22 39.90
## SAMD4A 5.36 3.82 4.71 1.72 5.38 5.01 4.12
## RUNX3 7.79 14.50 14.25 7.23 8.59 6.48 13.17
## MRE11A 13.70 11.22 19.70 3.74 11.04 9.99 12.33
## PLEKHB1 15.72 34.68 31.16 19.11 20.21 17.84 24.27
## SERPINB1 119.12 84.19 88.69 43.05 77.94 95.75 71.31
## CYP3A43 0.00 0.00 0.00 0.03 0.00 0.00 0.00
## SLC7A9 0.14 0.04 0.11 0.09 0.07 0.10 0.11
## SPAST 5.19 4.06 7.43 4.18 6.41 7.06 5.56
## NRXN3 0.36 0.62 0.66 0.20 0.30 0.59 0.60
## OSBPL5 4.63 6.92 8.71 2.94 6.71 4.40 6.33
## AQR 18.00 8.97 16.71 5.57 19.57 19.82 16.33
## CPS1 0.07 0.07 0.03 0.02 0.02 0.07 0.24
## C8B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## FHL1 17.53 19.82 21.31 9.74 16.15 17.05 14.63
## RTFDC1 128.28 102.89 112.86 76.04 111.59 124.76 120.96
## GABRA1 0.03 0.00 0.00 0.01 0.11 0.69 0.00
## NLRP2 0.00 0.05 0.00 0.04 0.00 0.01 0.00
## SLC45A4 4.34 3.51 3.81 1.65 3.96 5.67 4.25
## RNF10 54.63 66.96 59.47 78.60 82.77 59.17 66.91
## ZNF839 13.36 5.85 8.07 7.96 12.65 11.85 10.68
## ZDHHC6 29.22 18.77 28.74 13.49 25.29 18.90 21.93
## GRAMD1B 0.56 1.30 1.33 0.26 0.62 0.29 0.81
## RNH1 130.46 133.23 122.99 95.83 127.59 136.36 150.53
## NDUFS1 41.24 35.78 41.37 13.58 32.67 43.22 32.99
## RB1CC1 6.47 6.75 9.82 4.28 7.35 8.48 7.99
## ERP44 28.08 25.44 31.21 22.05 29.97 28.72 27.02
## ALAS1 55.34 49.94 48.04 26.29 38.24 60.90 45.28
## BIRC3 11.97 6.48 8.78 2.90 4.10 3.18 4.00
## AKAP11 6.08 3.02 6.97 1.82 6.11 7.09 4.54
## GLRX2 40.79 39.90 47.48 38.84 41.70 32.77 41.05
## SNAPC1 6.61 3.24 4.94 4.44 5.67 6.44 4.45
## DERA 60.62 42.59 57.41 39.56 55.60 53.89 56.01
## STRAP 226.64 154.26 161.98 331.90 220.67 243.38 207.80
## ABCC2 0.07 0.04 0.14 0.16 0.13 0.20 0.08
## DEF6 12.96 8.84 10.37 6.73 13.40 11.82 11.13
## PLEKHO1 2.66 4.90 4.33 1.44 2.71 2.64 2.53
## GCLM 35.89 22.62 24.29 40.20 53.36 57.79 52.94
## UBR2 3.75 3.39 4.86 2.22 4.10 4.53 3.75
## EHD2 2.75 2.44 3.67 1.13 3.04 2.75 3.19
## DEPDC1 4.80 3.34 6.99 2.08 3.51 4.15 3.63
## CCDC28A 5.65 7.79 7.88 9.25 6.17 6.34 7.18
## RRAGD 24.27 22.39 24.21 18.98 23.80 33.82 25.90
## HSF2 4.89 4.51 6.42 3.66 5.07 6.29 5.38
## PHF20 8.25 7.94 9.33 4.17 7.75 10.22 8.38
## HSD17B6 0.93 1.52 1.14 0.88 0.56 0.69 0.64
## NR1H3 11.39 17.33 14.94 15.11 12.12 9.97 14.31
## TYMP 0.93 2.05 1.32 1.39 0.60 0.55 0.83
## NCAPH2 40.82 44.36 46.56 26.08 34.26 23.33 39.91
## TOMM34 181.51 124.52 138.41 76.61 145.09 159.98 158.71
## SEC63 44.97 31.94 40.22 24.75 44.13 34.46 33.98
## KPNA6 13.41 10.08 12.39 4.73 10.93 14.78 11.35
## VIM 715.91 422.57 451.97 291.36 605.07 581.18 558.09
## RTEL1-TNFRSF6B 6.98 4.67 7.28 1.75 6.20 4.81 7.21
## FAS 18.76 15.13 22.10 8.60 20.65 19.36 19.66
## RNASET2 46.62 48.30 41.65 53.13 47.33 44.95 50.06
## CD44 254.54 214.95 260.29 111.07 210.09 229.33 197.60
## KCNG1 3.58 5.22 5.58 1.78 2.43 2.57 3.98
## AGPAT4 0.12 0.17 0.06 0.14 0.18 0.26 0.14
## SLAMF7 0.26 0.00 0.09 0.02 0.18 0.23 0.04
## BTN3A1 0.80 0.95 1.70 0.12 0.97 1.21 0.92
## MIPEP 37.06 38.45 41.24 44.91 37.45 25.89 37.75
## PRKCH 1.48 1.66 2.06 0.68 1.15 1.43 1.24
## INSRR 0.00 0.01 0.01 0.01 0.00 0.00 0.00
## IFNGR1 18.10 12.75 15.86 10.08 16.60 20.74 17.35
## B4GALT7 46.29 32.37 32.24 27.57 41.15 41.98 39.90
## SH2D2A 11.77 5.26 7.59 3.82 7.97 12.01 6.39
## VRK2 24.54 9.67 19.75 7.96 21.81 29.26 20.52
## TNFRSF1B 51.36 50.59 51.44 23.48 37.32 28.57 45.36
## VEZT 33.24 20.36 34.06 12.98 28.87 20.31 25.22
## POU2F2 0.27 0.48 0.33 0.07 0.15 0.48 0.21
## BRD9 48.23 35.46 46.65 32.14 52.59 57.92 53.26
## SNX1 32.55 32.52 38.86 11.49 25.61 24.43 30.79
## TBPL1 19.78 15.14 19.77 12.63 18.50 21.77 16.18
## ARNTL2 24.07 22.94 25.47 8.11 18.26 22.01 19.69
## BCLAF1 58.23 38.26 87.51 13.34 56.36 74.89 57.68
## SLC39A9 28.66 28.81 30.39 29.61 29.21 34.23 30.09
## ANK1 0.21 0.28 0.17 0.06 0.34 0.11 0.15
## IBSP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TFB1M 13.50 11.52 15.03 9.94 14.34 10.32 12.33
## RABEP1 38.61 27.09 35.02 18.11 31.97 24.48 29.79
## HMGB3 180.91 146.69 177.49 119.90 146.10 135.66 146.87
## NUP160 22.18 15.51 22.82 9.09 18.84 20.43 18.77
## BAK1 19.90 12.77 12.30 14.83 17.83 27.44 16.87
## MUSK 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## IKZF2 0.13 0.15 0.07 0.19 0.11 0.29 0.03
## GRN 167.24 212.46 200.13 125.62 211.63 202.70 206.27
## FAM13B 6.90 4.58 6.89 3.35 7.30 6.69 8.09
## ARHGAP31 1.43 0.73 0.67 0.23 0.90 1.10 0.92
## CENPQ 10.26 6.14 10.47 8.46 11.12 10.10 9.19
## SARS 96.13 90.62 87.32 92.79 92.70 119.10 116.85
## RANBP3 27.45 32.95 38.73 14.63 28.13 24.85 32.12
## ARID4A 1.87 1.51 2.46 0.73 1.99 2.77 1.86
## TSSC1 32.13 33.52 33.79 27.22 30.95 28.92 36.15
## PNPLA6 13.73 27.13 25.50 20.91 17.11 11.68 19.73
## IFT88 8.45 5.70 9.92 7.83 9.29 8.07 8.80
## ALG1 34.63 36.19 35.50 25.50 28.63 25.15 33.94
## ZCCHC8 12.38 6.58 11.94 5.70 13.39 10.01 10.42
## ABCF2 60.87 58.03 70.73 20.01 46.67 54.30 65.07
## CHPF2 21.93 20.04 20.78 19.22 21.26 22.04 22.97
## LRRC7 0.03 0.02 0.04 0.10 0.01 0.05 0.04
## FUT8 16.61 13.79 19.47 8.88 15.08 11.91 12.52
## UBA6 8.36 4.68 10.29 3.79 8.19 7.11 6.21
## GAB2 2.18 2.61 3.09 1.17 3.48 3.70 3.11
## ATP6V0A1 17.64 16.96 17.54 15.82 15.52 16.38 22.54
## PIAS1 6.06 5.29 9.66 1.90 5.67 5.29 7.00
## SLC4A7 5.54 2.27 5.49 1.08 4.08 7.07 3.56
## APBA2 0.30 0.37 0.34 0.12 0.25 1.07 0.12
## MAP2K3 99.87 63.84 63.87 46.24 68.21 85.59 70.67
## EFCAB1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMSB10 7105.67 6851.87 6502.08 11260.62 8048.05 6967.01 7473.26
## ASTE1 6.10 4.17 5.62 3.20 4.84 5.73 4.84
## RNF19A 5.26 4.52 5.74 2.94 5.40 5.62 6.21
## PEX3 19.39 13.95 20.64 10.61 19.03 18.36 19.98
## GABARAPL2 51.95 62.31 62.56 66.50 55.77 49.24 50.21
## MYOC 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SH3YL1 10.96 12.07 16.03 10.90 14.77 15.22 13.16
## FAM136A 147.35 131.23 149.38 113.91 123.05 117.10 133.92
## VCL 33.26 13.77 19.40 11.36 29.25 52.03 24.75
## DEPDC1B 5.85 5.69 9.57 3.54 5.67 3.90 5.94
## DAPK2 0.16 0.24 0.24 0.14 0.46 0.41 0.22
## NSMAF 30.17 23.51 32.39 14.64 26.50 24.40 29.14
## ADSS 22.81 17.93 25.36 14.75 21.46 25.33 20.14
## STAP1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TIMP2 221.58 158.35 196.36 145.49 245.03 275.64 222.31
## RFC1 27.96 17.22 28.48 11.25 22.85 28.11 29.63
## TBC1D23 7.59 5.03 8.59 6.78 6.84 7.59 6.45
## CUL3 59.48 64.23 60.31 61.37 55.99 51.54 55.99
## MYOM2 0.00 0.00 0.00 0.03 0.03 0.15 0.00
## OTC 0.00 0.00 0.02 0.00 0.00 0.02 0.00
## CYP46A1 0.35 0.16 0.18 0.26 0.36 0.47 0.25
## ZZZ3 16.35 10.17 15.07 12.16 16.31 21.54 15.49
## SLC18A1 0.01 0.00 0.00 0.05 0.00 0.02 0.00
## USP2 0.35 0.18 0.20 0.24 0.47 1.62 0.14
## CASR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TUBG2 7.36 8.43 11.41 3.30 9.18 6.15 7.83
## RPL26L1 147.76 111.78 118.75 176.01 156.55 132.82 138.06
## FLT4 0.09 0.00 0.03 0.01 0.07 0.12 0.09
## NSUN2 95.98 63.49 88.07 46.35 81.12 82.22 81.03
## FBXO42 5.85 6.95 7.31 3.22 6.75 6.12 7.53
## MFAP3 10.95 6.04 10.29 3.80 8.92 13.38 7.91
## MRI1 12.51 13.15 17.01 4.56 11.84 8.29 12.95
## METTL1 95.94 83.10 87.69 58.03 75.44 82.01 83.89
## HOXC8 5.89 3.51 4.93 4.07 6.59 5.92 5.47
## AGA 3.60 2.73 4.36 2.42 3.15 3.67 4.11
## PI4K2B 12.40 11.19 15.92 8.63 12.49 13.35 10.83
## BOD1L1 7.21 3.12 6.48 1.46 8.25 7.51 5.66
## MAT2B 40.70 29.38 51.03 36.28 41.25 47.15 38.72
## TLL1 0.00 0.00 0.00 0.04 0.00 0.00 0.00
## EDC4 26.76 24.79 35.41 17.90 27.72 27.39 31.91
## TRIO 19.07 10.96 14.76 5.07 19.09 18.75 17.47
## VCAN 0.12 0.00 0.01 0.00 0.14 0.40 0.03
## CLEC16A 7.98 8.95 9.54 5.49 7.66 8.42 9.02
## MSR1 0.07 0.13 0.10 0.00 0.08 0.06 0.08
## CDH1 41.01 34.01 27.90 23.25 31.24 34.23 20.74
## SKIV2L2 31.90 19.28 29.83 7.28 24.24 27.32 23.89
## DNAH5 2.55 1.18 1.34 0.78 2.04 2.75 1.70
## ZFYVE16 5.54 5.04 8.12 3.93 8.38 6.95 6.40
## FAM65A 17.65 15.80 18.15 7.23 20.17 19.12 20.21
## C6 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## RAI14 11.71 6.22 10.15 5.95 10.42 15.19 10.59
## SOX30 0.38 0.39 0.42 0.21 0.26 0.40 0.18
## PNKP 43.85 43.28 51.50 21.56 40.11 35.76 40.17
## BEST2 0.04 0.29 0.12 0.16 0.23 0.23 0.08
## PHLPP2 2.25 1.55 1.92 0.90 2.43 2.95 2.20
## SPDL1 22.45 11.02 23.26 6.50 21.85 16.34 16.60
## STAU2 4.79 5.84 10.11 2.66 6.25 5.71 6.20
## PQLC2 20.24 20.16 18.33 18.42 23.62 20.39 22.80
## CTNS 9.79 9.45 10.68 4.61 9.80 11.78 11.96
## RTN4R 3.81 5.92 6.43 3.39 7.59 5.33 8.09
## PHF23 39.09 38.69 37.71 29.65 37.23 43.01 36.15
## CDH10 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## INPP4A 2.54 2.57 3.75 1.26 2.97 3.07 3.17
## RAB27B 0.40 0.14 0.44 0.17 0.42 0.93 0.43
## PSMA4 182.15 227.85 214.69 247.38 183.84 146.70 186.69
## MYO16 0.05 0.02 0.06 0.10 0.06 0.08 0.06
## LSG1 59.94 34.35 45.76 23.39 50.00 67.42 48.99
## PARP3 9.28 7.00 9.64 3.48 9.79 11.75 9.10
## TNC 28.06 8.88 13.29 1.87 11.59 9.60 8.00
## THAP3 11.01 12.46 10.28 16.31 12.68 11.37 11.60
## FAM65C 0.24 0.13 0.09 0.08 0.08 0.10 0.16
## TDP1 14.79 14.26 18.64 7.72 12.38 13.28 14.77
## AIFM2 21.13 21.86 21.43 21.76 22.97 23.29 23.53
## C2orf83 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SPATA7 5.02 3.58 5.11 2.01 4.05 5.82 3.62
## MED17 32.06 22.47 34.41 11.14 31.88 33.79 30.98
## RETSAT 10.98 13.46 16.79 6.00 13.74 11.18 16.21
## CAPG 147.79 170.13 147.60 147.64 144.52 166.66 155.84
## AP2S1 231.17 302.10 233.15 353.72 224.44 205.61 261.74
## USH2A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZPBP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TG 0.21 0.09 0.08 0.27 0.13 0.29 0.23
## ADAM28 0.02 0.00 0.00 0.00 0.00 0.00 0.00
## BARX2 2.40 2.52 2.31 0.94 1.85 1.67 2.01
## DCUN1D1 25.26 14.91 27.99 10.15 25.13 28.58 24.29
## JADE2 9.66 16.83 17.35 6.96 8.51 12.36 12.50
## ZIC2 6.42 4.57 6.43 3.12 7.29 8.52 6.70
## LCP2 0.00 0.00 0.05 0.00 0.03 0.03 0.00
## TRIT1 26.99 21.12 25.97 20.32 24.89 24.46 24.16
## ADRB1 0.07 0.03 0.07 0.04 0.08 0.10 0.05
## GUCA2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CUL7 2.19 2.24 3.09 0.80 2.62 2.35 3.10
## CTNNA1 183.86 194.78 220.22 145.97 216.45 175.52 230.42
## PHKA2 12.99 9.48 12.59 6.85 14.09 10.87 13.91
## CNTLN 1.25 0.50 1.26 0.37 0.88 1.09 0.80
## EPHA3 0.00 0.00 0.00 0.00 0.00 0.01 0.01
## HSPA5 842.60 455.35 516.03 986.64 724.92 1227.57 585.38
## DSG2 17.63 12.27 23.29 5.01 15.65 17.14 15.24
## GEMIN8 7.83 7.24 7.89 8.93 9.40 10.44 8.69
## OFD1 22.07 20.06 24.67 17.98 25.76 19.32 25.24
## GPM6B 0.14 0.31 0.45 0.13 0.33 0.22 0.35
## MAGEC2 1.27 0.89 1.09 0.96 1.07 2.81 0.80
## PREX2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## WDR37 3.68 2.40 2.98 2.73 4.00 5.33 4.53
## YTHDC2 8.43 4.50 10.18 3.34 8.03 6.10 7.14
## CTPS2 13.43 9.77 16.10 5.87 13.11 9.76 13.28
## ATP6V1H 28.28 21.24 20.82 30.12 25.93 41.70 24.70
## POLR2B 35.76 29.71 40.84 22.02 36.98 39.00 39.28
## FAM214A 0.73 1.74 1.80 1.54 1.69 2.35 1.70
## ARAP2 2.04 1.52 2.58 1.21 2.62 1.84 1.98
## TPR 25.94 19.91 27.66 9.37 22.40 22.46 24.39
## CP 0.00 0.16 0.00 0.11 0.11 0.08 0.00
## KIAA0556 3.88 3.97 5.69 1.27 4.74 5.63 6.14
## DTNBP1 14.61 16.18 15.18 11.72 14.30 10.43 15.37
## XK 1.34 0.93 1.74 0.61 1.22 1.71 1.07
## ANO2 0.36 0.11 0.48 0.11 0.58 0.59 0.31
## C12orf4 13.12 5.76 9.35 4.61 9.49 12.29 7.91
## SCML1 23.11 9.63 26.22 15.98 27.78 24.13 25.34
## WWC3 5.93 4.61 6.42 4.79 6.16 5.11 6.62
## ARHGAP6 0.01 0.03 0.00 0.00 0.00 0.00 0.00
## FAM184B 0.41 0.47 0.62 0.18 0.53 0.49 0.41
## MAP4 47.34 40.90 50.97 34.76 52.17 53.25 56.92
## GOPC 7.75 4.44 8.29 3.83 7.55 6.37 5.66
## ROS1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## USP28 6.78 5.89 10.31 1.28 6.14 7.81 8.14
## HDAC9 3.70 0.85 1.91 1.62 3.50 6.48 2.91
## TSPAN17 52.71 51.62 48.83 42.36 46.69 59.31 62.80
## NOP16 159.99 148.28 140.91 137.34 130.84 113.51 138.99
## CC2D2A 6.40 4.48 6.16 3.50 6.20 6.90 4.28
## RRM2B 4.68 3.54 6.51 3.23 6.10 8.43 5.98
## ZNF800 12.94 6.27 12.12 6.09 12.34 16.00 10.81
## TNFRSF17 0.00 0.14 0.00 0.05 0.00 0.05 0.06
## SNX29 2.87 1.94 1.79 1.19 2.20 3.12 1.67
## LMO3 0.01 0.05 0.06 0.02 0.09 0.07 0.04
## MRPS10 57.08 34.07 43.51 34.67 48.85 55.03 48.67
## GUCA1A 0.00 0.00 0.00 0.00 0.02 0.02 0.00
## RSF1 8.38 6.90 7.81 2.36 7.71 10.61 8.07
## VPS13D 10.22 6.68 10.83 6.00 11.44 8.19 10.01
## CELF2 0.23 0.16 0.31 0.05 0.24 0.33 0.26
## FAM120A 56.41 31.80 56.22 40.42 54.48 58.85 57.37
## R3HDM1 13.56 10.73 17.25 5.45 14.04 14.65 14.66
## COL9A2 0.36 0.27 0.48 0.20 0.48 0.94 0.22
## KITLG 2.14 0.85 1.89 0.71 1.57 2.75 1.80
## ERCC8 6.42 4.84 5.96 3.92 5.71 6.11 5.08
## ADAMTS6 0.10 0.07 0.02 0.00 0.04 0.02 0.03
## H6PD 7.31 10.02 6.91 2.63 5.71 6.13 5.74
## VAMP3 87.22 70.48 81.66 62.86 76.63 107.37 81.24
## PER3 0.99 0.92 1.23 0.55 1.18 1.25 0.88
## UTS2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TNFRSF9 2.73 0.98 0.40 0.17 1.39 4.86 0.76
## EPN3 0.01 0.11 0.07 0.00 0.04 0.07 0.11
## LTBP1 0.88 0.63 1.17 0.25 1.06 0.75 0.94
## RCN1 279.74 323.40 330.49 497.48 251.94 240.06 291.56
## ELN 0.01 0.07 0.07 0.14 0.04 0.06 0.01
## RFC2 115.62 112.13 131.93 91.10 94.47 79.81 111.76
## ARID1B 4.65 3.79 4.86 1.12 4.53 4.85 4.05
## CLPTM1L 147.11 153.13 147.87 140.21 119.64 125.60 143.11
## NEDD4L 23.00 16.28 20.96 13.29 20.41 23.99 22.89
## FOXP3 0.58 0.32 0.35 0.07 0.79 1.17 0.51
## PPP1R3F 1.83 5.03 3.75 4.37 2.67 1.87 3.21
## HEXB 97.18 81.60 76.66 128.76 102.09 117.62 108.57
## PTCD2 4.41 2.86 4.32 3.69 4.60 5.41 5.17
## KIAA2022 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## JKAMP 20.71 14.97 18.96 9.26 15.69 19.40 15.70
## DKK3 3.61 8.83 7.15 2.65 3.61 4.62 4.25
## ARHGEF5 13.05 14.78 14.74 6.57 13.34 15.46 15.48
## NFE2L3 107.14 75.15 128.54 85.66 116.10 66.67 115.50
## MCUR1 44.75 42.26 45.27 52.69 45.68 39.01 46.95
## LIMA1 11.87 15.16 21.07 10.54 14.87 15.03 17.96
## LETMD1 53.89 40.42 46.97 43.05 56.00 43.11 50.40
## SLC4A8 0.55 1.54 1.62 0.21 0.66 0.73 1.08
## LAMC3 0.01 0.02 0.04 0.00 0.02 0.02 0.04
## PTGER3 0.02 0.00 0.00 0.00 0.02 0.00 0.00
## TNIP3 0.00 0.00 0.00 0.03 0.01 0.15 0.01
## MAPK9 27.52 26.42 34.27 20.92 30.06 30.97 30.08
## COL23A1 0.00 0.03 0.01 0.00 0.02 0.00 0.01
## BCAR1 30.66 25.51 26.80 17.93 29.13 32.92 28.25
## FAM160A2 17.87 13.27 15.93 11.98 21.23 20.36 19.96
## HERPUD1 54.68 56.13 56.84 178.59 70.89 78.35 83.45
## HOMER3 14.97 20.80 18.02 11.57 14.25 14.83 17.03
## RAD51 48.95 34.43 42.43 29.42 33.54 31.99 41.03
## POLQ 6.82 3.31 6.25 1.63 6.25 4.84 5.39
## PIK3CB 20.25 18.63 26.39 14.48 18.40 18.10 21.61
## CYBA 203.98 260.62 234.63 268.35 233.96 179.56 219.92
## THOC3 69.72 71.11 78.89 57.16 69.66 51.68 76.11
## HEBP2 66.13 70.89 65.83 66.66 78.07 58.31 71.58
## MPHOSPH9 8.13 9.38 12.86 9.13 8.73 8.12 7.92
## PLEKHA5 8.17 6.14 8.31 4.42 10.10 11.15 7.24
## PRSS8 0.02 0.05 0.00 0.05 0.06 0.12 0.00
## SIKE1 23.03 15.16 17.89 17.91 22.74 27.63 16.70
## RRP12 68.51 44.99 42.56 41.34 50.59 61.27 56.49
## FNIP2 1.50 0.58 1.34 0.88 1.88 1.90 1.67
## MSMO1 15.33 9.40 11.21 19.49 20.50 36.22 14.75
## TTC17 31.26 20.04 26.77 14.64 31.63 43.37 26.93
## ALX4 0.00 0.03 0.01 0.00 0.00 0.01 0.01
## FSTL4 1.93 2.87 3.63 1.01 1.92 1.66 2.27
## FOXN3 5.23 11.12 12.26 5.01 7.88 3.79 10.95
## METTL24 0.00 0.00 0.03 0.00 0.00 0.00 0.00
## AKR7A2 30.77 45.91 43.03 34.27 28.01 23.45 37.86
## MRTO4 110.47 117.23 91.50 74.05 86.39 91.40 97.72
## NNAT 0.62 0.35 0.53 0.02 1.28 0.97 0.68
## USE1 37.25 44.45 38.48 36.91 32.95 33.93 35.75
## MCF2L2 1.19 0.68 0.67 0.78 1.23 1.90 1.19
## NRIP2 0.54 0.74 0.62 0.13 0.63 0.99 0.66
## LAMA3 114.01 57.54 60.68 37.62 79.20 64.09 66.97
## AP5M1 12.14 10.37 18.03 4.54 12.53 11.80 11.42
## ANAPC4 13.92 9.18 13.07 8.89 11.03 10.13 11.15
## KCNQ1 0.87 1.61 1.55 0.65 1.36 1.26 1.46
## TRAPPC3 67.76 71.81 85.87 42.50 62.00 67.41 77.47
## THRAP3 39.78 33.30 45.70 13.77 43.90 45.85 41.74
## PHPT1 126.56 145.28 128.08 148.33 135.90 114.09 136.79
## ENTPD2 4.51 4.78 6.41 2.39 5.46 3.68 6.38
## LY75 0.00 0.01 0.00 0.00 0.00 0.01 0.00
## ARID4B 4.61 2.95 5.70 2.07 5.08 5.40 4.19
## OPN3 2.87 5.50 5.52 4.53 4.15 3.41 4.23
## SDCCAG8 10.89 7.70 9.55 9.23 11.73 11.16 11.89
## PTPRN 0.12 0.20 0.16 0.23 0.22 0.54 0.24
## HHAT 6.00 2.73 3.84 4.71 6.85 7.46 5.82
## KIF1B 5.43 4.92 5.14 2.58 4.77 5.57 5.00
## FOXC1 7.13 6.15 8.75 2.66 6.95 7.55 5.99
## TBC1D22A 14.06 14.49 16.44 11.78 13.24 11.85 15.28
## SYNE2 3.35 3.81 6.34 1.32 4.87 2.26 4.35
## PLEKHH1 9.77 5.81 8.16 4.41 10.29 6.99 8.76
## ATP9A 13.95 21.70 28.55 7.94 17.37 14.41 19.71
## SPO11 0.00 0.00 0.00 0.00 0.00 0.03 0.00
## CBLN4 0.00 0.00 0.00 0.01 0.00 0.00 0.00
## CHRDL2 0.14 0.00 0.00 0.00 0.00 0.04 0.00
## FAM168A 3.51 4.33 5.63 1.47 3.64 3.37 3.85
## RELT 15.77 10.55 11.52 7.43 13.75 13.63 13.44
## GALC 0.81 0.47 1.11 0.29 0.54 1.05 0.92
## NOP58 227.91 119.16 161.72 155.19 207.47 213.42 181.18
## SZRD1 83.09 71.66 86.23 42.50 72.75 96.61 87.67
## KCNH2 2.49 3.97 3.82 2.12 3.79 4.38 4.06
## CUL1 38.33 37.53 45.15 17.66 35.24 30.43 41.29
## FAM114A2 15.22 6.89 11.16 10.17 12.41 19.48 12.13
## CYFIP2 3.46 6.08 5.22 3.29 4.26 3.92 4.58
## TAB2 8.48 9.57 13.54 5.89 9.24 10.37 10.11
## GINM1 27.76 22.72 30.20 18.48 28.71 29.68 27.42
## EIF2AK2 15.10 13.02 18.88 5.24 13.13 15.19 13.16
## USP36 62.49 37.29 43.02 41.17 61.08 83.25 59.70
## KMT2C 4.83 3.89 5.45 3.10 5.51 4.08 4.22
## MCOLN3 4.26 3.45 4.44 4.00 6.55 4.51 6.03
## CCDC85A 0.01 0.02 0.02 0.01 0.01 0.04 0.00
## PUM2 16.44 15.13 26.60 11.19 18.87 16.24 18.19
## MRPL43 62.17 69.97 69.22 54.86 64.77 54.19 64.65
## ITIH4 1.04 0.93 0.74 1.07 0.89 0.54 1.30
## ITIH1 0.00 0.00 0.00 0.00 0.00 0.02 0.00
## C4orf27 29.60 21.78 29.86 28.27 28.08 21.21 25.69
## ZFR 26.53 13.62 22.87 15.04 26.65 34.22 24.10
## ZNF280C 5.26 1.63 4.22 0.85 5.44 7.73 3.75
## NPFFR2 0.02 0.00 0.00 0.00 0.00 0.04 0.00
## PHF21B 0.01 0.00 0.00 0.01 0.00 0.01 0.00
## TRAF1 3.19 0.59 0.82 0.65 1.13 2.21 1.22
## RC3H2 26.88 13.98 14.70 11.67 14.09 20.98 13.02
## PCGF2 17.13 22.51 26.88 8.76 21.69 13.39 21.60
## IL17RB 11.32 9.36 12.94 3.89 10.44 8.44 8.79
## TRAF3IP2 0.15 0.18 0.25 0.14 0.62 0.47 0.22
## GYG2 1.14 1.08 1.46 0.34 0.76 1.05 0.60
## DCBLD2 174.62 116.12 159.32 101.26 148.52 134.37 138.63
## SERPINB3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SOAT1 11.41 6.21 9.89 3.27 8.56 12.24 8.84
## PKP2 19.72 15.44 25.61 10.83 18.40 23.93 20.95
## MSH4 0.02 0.00 0.00 0.00 0.00 0.01 0.00
## F7 0.01 0.00 0.00 0.00 0.01 0.01 0.00
## GDI2 180.45 154.93 192.56 115.18 160.86 164.99 187.18
## PRDM1 1.54 3.30 3.73 0.67 1.14 1.15 1.81
## ATG5 12.23 13.03 13.14 12.77 11.98 13.59 12.75
## TMCC3 0.44 0.30 0.61 0.15 0.29 0.40 0.32
## PITHD1 66.85 62.39 58.09 99.36 70.42 63.87 74.29
## MTA3 15.94 11.20 16.94 11.23 13.75 15.07 14.04
## USP13 7.16 4.49 7.15 2.38 5.46 5.67 6.09
## ATP11B 15.36 9.18 15.38 5.63 13.68 15.90 11.90
## LAMC2 71.87 35.44 43.87 16.77 36.58 44.56 39.17
## CDK14 1.19 0.48 0.98 0.41 0.55 1.95 0.54
## SEC61A1 230.81 168.24 190.37 148.37 202.78 244.48 215.85
## PPP1R12A 8.85 4.20 11.09 4.11 9.49 10.11 7.52
## RASGRF1 1.03 0.61 0.67 0.13 0.58 0.77 0.70
## CAMK2B 2.63 2.68 2.81 1.88 2.26 1.98 2.13
## CROCC 5.40 4.73 5.64 3.73 7.22 5.03 5.94
## POLR3E 21.89 22.47 33.98 10.75 16.54 11.43 21.83
## ATP2B4 7.77 4.39 6.69 3.26 5.38 4.47 5.35
## ZC3H11A 20.56 17.23 28.42 12.40 22.19 20.64 21.06
## RIOK2 39.08 24.02 27.74 38.82 38.89 37.90 31.93
## YIPF1 20.89 21.06 19.63 21.62 19.43 22.26 23.32
## NDC1 22.51 18.75 26.02 12.91 17.38 17.30 20.99
## DGKG 5.56 6.56 7.27 3.24 8.07 8.41 8.36
## FLYWCH1 11.96 11.92 11.58 9.32 16.34 13.92 18.05
## UNKL 4.05 5.29 5.90 6.94 4.62 3.98 3.89
## TBXAS1 2.33 2.05 2.40 2.31 2.21 2.45 1.95
## PARP12 16.55 9.82 13.84 7.31 13.16 14.84 11.63
## ALDH18A1 60.62 35.99 51.74 24.83 47.23 67.12 49.47
## TARBP1 9.23 13.93 16.78 12.65 13.48 8.10 15.69
## PET112 17.40 17.52 17.62 18.25 17.72 15.30 18.38
## MXD1 2.86 5.33 4.34 14.58 7.02 7.36 6.08
## CDK17 9.38 4.83 10.83 4.54 10.11 11.10 8.40
## DNAJC25 14.66 17.99 29.83 39.85 35.34 39.00 27.83
## SLC2A3 437.15 205.86 278.27 381.82 351.63 341.91 330.34
## PSD 2.93 3.98 4.28 1.36 2.74 3.93 2.59
## CTDP1 4.10 5.35 5.30 4.68 4.72 4.50 5.12
## YBX3 480.21 437.93 447.01 403.62 516.98 426.15 485.46
## STYK1 4.17 1.70 3.05 3.94 4.35 6.44 3.98
## WNK1 22.89 23.57 29.71 7.20 25.94 24.69 26.18
## CCAR1 34.91 30.28 41.25 28.08 41.18 29.77 33.71
## OGFR 61.36 61.40 63.04 38.18 51.19 41.77 50.67
## GNA15 0.06 0.04 0.01 0.03 0.08 0.14 0.00
## CREB3L3 0.04 0.07 0.02 0.00 0.07 0.25 0.01
## PIGV 8.61 7.15 9.53 5.01 8.12 8.46 8.10
## PTPRU 14.43 12.36 13.27 4.45 11.03 9.98 11.17
## SNRNP40 57.38 53.98 52.89 66.51 53.76 49.89 52.07
## RIMBP2 3.14 2.26 3.45 0.69 3.14 2.33 2.80
## COL11A1 0.00 0.00 0.00 0.00 0.02 0.04 0.00
## QSER1 8.31 4.66 9.00 2.62 6.72 7.91 5.99
## MPC1 52.49 54.93 68.26 83.26 71.82 57.20 64.21
## ACAA1 76.46 63.96 67.59 60.46 74.22 80.63 73.83
## BCAT1 0.10 0.02 0.02 0.02 0.11 0.28 0.05
## HDAC7 21.16 16.86 19.75 22.11 24.38 17.72 24.85
## LZTS1 0.67 0.37 0.98 0.07 0.39 0.32 0.35
## PRDM6 0.22 0.16 0.12 0.12 0.17 0.21 0.23
## WNT8A 0.00 0.00 0.02 0.00 0.00 0.00 0.00
## SPAG4 4.99 6.19 6.18 3.81 4.30 5.67 4.39
## NCKAP1 46.49 30.21 49.41 23.39 45.57 52.94 52.99
## MRPS35 81.85 64.27 75.63 53.35 67.59 81.29 77.60
## GUCY1B3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SFSWAP 18.24 13.92 18.81 7.75 17.83 16.78 16.20
## TNK2 63.08 85.57 94.13 47.73 75.58 56.27 78.70
## MON2 4.00 2.52 4.18 1.86 3.12 3.75 3.21
## CDH3 10.59 8.34 11.86 3.73 10.40 10.67 9.09
## ARSF 0.00 0.00 0.00 0.00 0.00 0.04 0.00
## GPBP1 37.73 33.77 35.96 28.43 29.99 36.10 32.23
## DGAT2 3.21 3.31 3.65 1.59 2.16 1.55 2.26
## ZNF112 1.95 0.92 1.68 0.80 2.41 2.32 1.68
## CS 170.28 135.22 169.72 70.95 142.18 166.31 154.92
## LTK 0.61 1.05 0.82 0.27 0.60 0.69 0.56
## MRPS24 215.25 267.47 228.63 302.83 203.64 184.24 226.78
## ELMO2 19.55 13.56 18.32 9.91 20.61 23.28 19.36
## WAPAL 14.27 10.64 14.00 10.72 13.56 14.22 11.40
## VMP1 276.70 165.04 268.78 111.38 241.61 216.08 206.09
## APPBP2 4.58 3.75 5.90 3.10 4.78 4.84 4.05
## POLD1 57.96 89.04 102.70 65.96 57.71 27.32 83.40
## SEZ6 0.77 1.18 0.68 0.24 0.62 0.70 0.77
## EIF4B 147.27 186.40 216.85 100.15 129.96 179.76 178.58
## SLC6A16 0.25 0.35 0.53 0.18 0.19 0.13 0.23
## GLTSCR1 3.86 4.20 3.63 3.76 5.42 4.95 3.91
## SPHK2 6.02 8.14 7.42 4.49 6.95 7.41 7.58
## RPL18 3319.45 3693.25 3127.49 4029.90 3603.22 3611.88 3526.79
## CA11 7.66 9.98 7.86 10.30 11.55 10.70 5.97
## ISOC2 92.54 98.57 80.10 99.76 83.80 98.07 86.75
## U2AF2 201.30 127.38 167.62 51.92 174.00 193.87 181.00
## EPN1 78.79 103.99 103.80 55.92 84.61 76.04 101.56
## MED29 30.34 23.24 29.65 16.30 28.32 33.38 28.73
## AHRR 2.59 5.08 6.11 1.44 3.98 2.28 4.56
## GSC2 0.06 0.06 0.03 0.00 0.03 0.18 0.00
## ZNF275 8.25 4.28 6.96 4.48 10.13 11.24 9.65
## MTMR1 21.27 13.35 22.42 6.22 17.27 17.15 17.47
## GPC1 84.52 90.02 77.17 50.52 80.92 73.66 92.28
## ADCK1 5.61 6.61 7.25 4.12 7.13 4.87 6.81
## HAGH 25.58 33.01 44.01 21.20 24.96 24.27 26.43
## RNF4 39.03 28.13 36.68 18.10 32.43 44.47 36.40
## CASP8 26.93 15.06 21.35 7.27 20.63 24.54 16.52
## LIMCH1 1.25 0.97 1.93 0.51 1.58 1.56 1.72
## ASUN 79.08 56.23 89.95 83.75 83.77 69.86 76.99
## TM7SF3 36.88 48.31 48.91 13.19 30.32 38.90 39.42
## DLX3 1.66 4.44 3.99 1.51 2.25 2.47 3.37
## SPA17 14.16 12.23 15.23 9.39 13.75 11.24 12.91
## TSPAN32 0.22 0.32 0.53 0.05 0.17 0.23 0.11
## WISP2 0.02 0.10 0.00 0.00 0.07 0.02 0.03
## DMRT3 0.09 0.08 0.10 0.06 0.10 0.13 0.05
## ST3GAL6 1.23 1.36 1.86 0.78 1.31 0.83 0.63
## ATP2C2 1.57 0.93 0.95 0.72 1.75 2.62 1.27
## NGFR 158.10 89.43 93.15 94.79 154.22 242.09 130.64
## CDON 1.62 1.88 2.49 0.53 2.46 2.51 2.01
## TAF2 12.36 5.22 10.99 2.34 9.06 12.41 9.21
## HIPK2 3.04 4.32 3.69 1.25 3.34 3.33 2.91
## TNPO3 27.89 19.29 31.61 2.98 26.50 34.74 30.70
## MEF2BNB-MEF2B 1.75 2.36 1.73 3.66 2.49 2.06 1.54
## RFXANK 58.70 102.57 75.42 78.48 67.60 40.54 76.82
## TMEM161A 24.51 21.64 22.45 26.39 21.26 20.01 24.21
## LPAR2 17.89 22.94 24.40 15.71 16.89 18.33 20.28
## CTSA 181.89 188.34 182.43 162.61 205.45 177.33 210.40
## SUGP2 14.93 15.00 18.73 22.18 18.75 13.73 20.47
## SLC12A2 22.35 12.62 20.62 6.68 14.77 12.52 14.95
## SNX24 14.47 8.61 11.20 10.07 13.39 12.58 13.10
## EYA2 0.17 0.18 0.37 0.11 0.13 0.18 0.17
## CNN2 151.80 109.25 154.87 71.34 139.01 146.06 154.48
## ABCA7 3.86 7.57 7.57 5.02 5.34 2.83 5.98
## SNCAIP 0.00 0.00 0.00 0.00 0.00 0.02 0.00
## DDX20 9.55 6.35 9.15 4.83 8.33 9.13 8.92
## BTBD1 35.07 23.26 35.38 21.95 29.25 37.88 30.81
## FAR2 1.09 0.57 0.95 2.98 0.87 0.93 1.21
## BCAS1 0.03 0.01 0.03 0.00 0.06 0.03 0.04
## POU1F1 0.00 0.00 0.02 0.02 0.02 0.05 0.02
## CHI3L2 0.00 0.00 0.01 0.00 0.05 0.06 0.02
## SBNO2 10.85 7.70 10.48 6.34 10.66 10.73 11.39
## PMS1 9.69 8.23 12.13 7.15 8.76 9.08 8.66
## HMG20B 18.94 42.40 43.36 34.90 27.70 16.56 35.98
## CALCRL 0.01 0.00 0.00 0.00 0.06 0.06 0.00
## TAF11 20.65 17.01 21.06 18.90 16.41 15.76 17.60
## ANKS1A 2.65 2.57 3.34 1.01 2.28 2.30 2.27
## AP3D1 32.71 30.68 33.95 22.12 32.56 32.98 36.87
## ZNF76 13.43 14.29 16.63 7.61 17.16 12.27 16.78
## SLC9A3R2 17.13 30.60 26.40 16.90 20.26 15.15 25.31
## NTHL1 11.62 22.16 18.49 15.64 12.22 10.92 17.11
## UHRF1BP1 3.37 2.75 3.57 2.03 3.45 4.29 3.58
## GNAI3 54.20 40.66 51.06 40.67 47.11 61.31 50.68
## IPO5 107.79 90.37 122.22 51.30 83.14 92.42 107.89
## OAT 79.75 47.84 69.67 70.31 90.55 119.90 67.55
## WDR3 27.74 11.41 18.76 8.63 20.83 30.84 20.76
## PKN2 7.23 4.35 10.36 3.50 8.56 8.56 8.15
## WDR18 29.44 43.63 32.81 32.95 27.48 23.83 33.68
## TRAM2 5.24 3.83 5.04 1.57 4.66 5.01 4.86
## NTN1 1.78 1.26 1.84 0.55 1.37 1.60 1.28
## GLP2R 0.02 0.01 0.01 0.07 0.07 0.17 0.09
## MCM10 20.60 11.83 19.03 5.19 14.50 14.50 16.48
## DGKA 11.98 15.18 16.68 5.15 13.35 6.23 16.74
## ERBB3 5.62 16.67 16.02 5.56 9.37 5.03 10.07
## ROPN1 0.10 0.02 0.09 0.02 0.14 0.20 0.17
## ANKRD44 0.28 0.63 0.77 0.23 0.62 0.87 0.60
## KARS 194.91 177.56 179.07 178.09 183.62 182.21 193.33
## ADAT1 37.33 29.29 34.96 14.17 33.56 31.97 31.65
## PDIA5 39.05 39.95 41.13 29.75 35.65 36.97 32.81
## TBC1D22B 3.76 2.99 3.72 2.50 3.95 4.39 3.76
## NDUFB4 222.93 253.78 257.66 211.06 241.89 207.67 227.85
## SPEN 14.28 12.42 15.65 2.42 15.60 12.44 14.57
## MYLK 0.98 0.52 0.98 0.21 1.67 2.39 0.71
## ZC3H15 99.24 64.39 88.07 63.93 84.09 108.23 84.14
## MAP2K4 12.47 9.11 11.05 9.28 11.99 14.25 11.95
## TMEM206 7.54 5.16 8.58 5.78 8.01 11.92 6.97
## SNAP91 0.06 0.00 0.01 0.00 0.00 0.00 0.00
## SLK 12.17 8.21 14.09 6.68 12.08 14.08 10.66
## CYB5R4 12.55 10.92 13.97 5.26 9.38 10.19 9.10
## COL17A1 1.76 1.61 1.89 0.35 1.41 1.09 1.15
## GSTO2 22.99 18.08 16.05 23.79 19.49 21.00 16.42
## SEC61A2 4.10 2.66 4.07 1.91 4.44 5.76 4.00
## PRKCQ 2.07 1.39 2.13 0.40 1.84 2.00 1.49
## TLE2 3.05 4.67 4.16 3.72 2.48 3.53 4.04
## ASB1 47.92 38.56 40.28 45.11 35.54 33.26 38.18
## FAM107B 39.36 22.96 33.66 18.61 32.75 40.18 33.40
## ME1 10.98 7.81 9.29 9.93 11.42 12.92 12.14
## TBC1D1 17.82 21.39 22.54 11.45 13.58 12.88 16.60
## CDK13 12.46 9.01 14.87 4.10 13.16 11.71 12.32
## MTHFD2 114.54 79.34 114.09 125.87 107.54 120.37 118.67
## SLC9A7 5.92 4.81 4.82 2.04 3.76 6.62 4.09
## FOXJ2 10.62 6.26 9.22 3.91 9.24 12.33 9.64
## YBX1 1022.25 927.71 1164.34 703.09 1041.29 986.22 1068.67
## PDE4A 4.29 5.76 7.53 1.97 5.22 4.19 5.98
## PPP2R5A 14.27 12.87 15.29 11.45 15.81 17.00 17.07
## CTNNA2 0.24 0.15 0.16 0.08 0.16 0.15 0.12
## ELAVL1 54.36 45.49 63.42 22.74 48.21 55.10 53.07
## TIE1 0.20 0.30 0.24 0.08 0.48 0.18 0.07
## DIP2B 8.20 4.28 5.89 2.52 6.70 10.04 5.93
## SMARCD1 59.78 46.82 61.85 15.76 60.35 58.10 57.56
## KDM4A 5.52 5.67 6.84 3.64 5.85 5.48 7.23
## NFYC 21.77 17.39 23.38 10.05 24.13 29.49 19.10
## ZMYND12 0.73 0.49 0.72 0.42 0.61 1.18 0.47
## SLC9A3 0.51 0.88 0.83 0.15 0.61 0.90 0.66
## NGEF 3.93 2.57 3.15 1.20 2.82 4.55 2.31
## ASPM 4.17 4.91 8.39 1.60 3.95 2.60 3.59
## CD84 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ELOVL1 122.35 96.95 98.50 40.74 102.29 125.72 104.24
## SPI1 0.05 0.10 0.13 0.17 0.34 0.13 0.09
## ZNRD1 67.75 38.89 40.48 61.81 63.10 89.29 53.66
## MPPED2 0.00 0.02 0.10 0.00 0.06 0.08 0.00
## CLDN18 0.03 0.00 0.02 0.00 0.00 0.01 0.01
## ZBTB11 7.24 3.09 6.84 2.19 6.63 7.74 5.08
## ATXN3 14.19 12.48 17.45 6.19 15.67 16.06 15.02
## GOLGA5 29.35 24.52 30.94 40.15 29.24 28.03 28.44
## FGFR2 0.97 0.96 1.60 0.41 0.80 0.65 0.94
## LRRC40 6.27 3.73 9.13 2.85 7.20 4.95 6.45
## ISOC1 33.95 20.79 37.40 17.37 28.45 28.93 22.59
## EML1 2.33 0.44 1.36 1.73 1.65 2.95 1.29
## TRMT11 11.54 7.54 13.25 6.15 7.55 7.23 8.29
## THUMPD1 15.40 8.36 16.39 6.35 14.05 15.27 12.85
## MSANTD3 41.00 35.29 36.58 27.06 34.54 33.67 37.84
## KIF26A 2.61 5.04 5.60 1.04 2.49 1.98 3.28
## ATG2B 2.84 2.08 3.33 1.47 3.49 4.16 3.05
## ARFGEF1 10.55 7.83 12.43 6.11 9.44 7.56 10.40
## ACSM2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZFAT 2.39 2.90 3.62 0.76 2.21 2.19 2.58
## MTFR1 16.49 12.74 18.98 17.06 16.11 20.22 18.16
## STAG3 0.93 1.08 1.37 0.28 1.46 0.94 0.93
## FECH 6.49 5.32 7.92 4.01 5.40 9.67 6.23
## MYO9A 2.20 2.80 2.52 0.73 2.57 2.62 2.44
## DDX3Y 0.00 0.00 0.00 0.00 0.00 0.05 0.00
## PFKP 42.52 29.51 35.83 13.30 33.50 33.48 38.06
## IDI1 8.18 8.16 9.71 10.68 10.81 19.22 9.64
## SP100 27.23 19.24 21.39 17.49 26.15 30.93 22.00
## KLF6 29.05 17.35 20.96 12.78 32.22 43.30 28.65
## PPAP2A 5.87 7.07 6.74 3.28 6.56 6.79 5.42
## NEO1 11.38 10.98 14.88 4.16 10.64 14.23 14.47
## TRAM1 49.96 32.44 55.77 20.05 46.97 61.80 45.10
## PHKA1 4.79 4.84 6.53 2.45 4.62 4.46 5.36
## TNFRSF1A 45.81 36.11 47.22 24.08 44.64 46.38 51.68
## CACNB1 5.03 3.67 5.00 2.41 5.78 5.46 5.57
## EVI5 4.40 3.90 4.31 2.03 3.83 5.28 4.23
## STOML1 7.50 4.94 4.21 3.41 5.51 6.66 6.45
## PKM 770.19 1006.92 927.40 418.98 677.27 764.20 900.36
## DHX29 12.56 7.03 10.50 5.74 11.13 15.32 10.64
## DNTTIP2 94.73 77.57 66.48 103.79 88.84 104.53 83.65
## METTL22 14.66 15.25 16.98 11.78 13.43 15.64 15.89
## TP53BP1 7.15 6.19 7.33 2.93 5.14 6.32 5.49
## TRO 0.07 0.01 0.08 0.03 0.07 0.05 0.03
## RRP15 30.43 17.17 20.50 10.20 19.48 31.42 23.22
## RHOA 438.74 447.68 474.52 403.08 381.41 441.05 464.91
## DHX8 29.40 29.76 26.35 24.04 28.70 26.01 27.09
## PRKCZ 17.43 28.75 27.61 20.63 25.23 23.04 32.36
## ZFY 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## IARS2 37.57 37.18 50.35 33.56 36.61 31.32 42.43
## SYT1 4.03 6.49 8.89 2.50 5.31 5.38 6.03
## NAV3 2.07 0.23 0.24 0.12 0.97 1.41 0.86
## IDH3G 56.07 66.76 69.29 48.59 53.31 53.13 67.11
## ROGDI 12.45 12.86 14.83 7.38 13.14 17.27 11.67
## PDZD4 6.67 5.56 5.88 4.90 6.98 7.72 6.98
## ATP2B3 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## ROCK1 16.58 7.95 16.12 6.43 15.65 20.77 14.20
## CBFB 63.69 34.37 66.09 39.90 68.15 78.67 55.11
## PDK3 6.44 10.67 10.90 3.08 6.34 5.11 7.46
## HYAL2 54.95 54.64 59.61 29.87 51.24 54.06 49.05
## HDAC4 8.00 7.32 8.81 3.16 7.08 7.55 7.95
## RASSF1 23.40 27.56 24.33 19.56 21.98 17.29 24.86
## FGFR3 0.85 1.19 1.53 0.37 1.25 1.36 0.90
## IFI35 21.33 22.48 20.87 8.55 16.44 19.84 16.48
## HEATR6 12.34 6.99 8.79 1.82 9.07 10.92 7.70
## COASY 68.64 114.75 104.18 52.95 63.02 58.78 80.66
## PLEKHH3 0.76 2.04 2.32 1.07 1.62 0.38 1.25
## MEF2A 8.50 4.96 9.65 3.73 9.26 15.29 8.31
## OTUD5 39.58 46.65 49.75 27.77 39.41 37.62 46.45
## TFE3 24.25 25.28 27.02 18.59 27.83 32.18 30.86
## TBC1D25 3.29 5.46 5.24 1.46 3.46 2.58 5.11
## ACSL4 60.56 19.51 45.33 22.08 51.33 60.60 44.33
## INPP5A 8.22 8.06 9.11 7.37 9.56 8.70 9.64
## GPKOW 24.51 36.30 30.29 16.61 20.44 19.43 27.02
## GRIPAP1 17.90 17.99 22.26 6.61 17.50 14.40 16.55
## FTSJ1 107.32 102.32 111.47 90.51 97.87 85.39 106.17
## PRR11 10.60 14.08 15.22 2.29 7.41 6.68 8.53
## REEP1 3.21 7.16 8.14 2.72 3.84 2.49 4.19
## ATP11A 7.54 5.11 7.86 1.49 6.46 7.57 5.76
## POLR1A 11.88 10.18 10.44 2.54 8.35 11.09 11.47
## LAPTM4A 104.95 112.85 137.00 151.13 118.01 116.62 119.67
## TTC7A 14.90 12.47 15.70 11.39 15.69 16.54 19.28
## IP6K2 48.01 47.85 56.23 36.50 49.42 47.01 49.85
## STON1-GTF2A1L 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SRBD1 6.90 4.45 7.90 3.43 6.83 6.26 6.82
## CYFIP1 30.20 27.47 33.75 17.73 25.76 23.36 32.41
## KIF2A 9.15 10.24 13.54 2.81 8.49 10.31 9.45
## RASGRP2 1.05 1.16 0.36 0.81 1.42 0.76 1.13
## PSME4 49.22 43.19 40.66 33.76 43.32 41.00 37.35
## IFT80 10.45 5.92 11.78 4.46 9.82 8.73 8.65
## SIRT2 25.72 28.89 28.78 18.31 24.38 28.75 30.07
## ERLEC1 33.98 30.19 38.78 26.73 32.09 34.47 33.29
## PPP2R5B 3.28 3.73 2.91 0.87 3.25 3.16 2.99
## PYGM 0.25 0.14 0.22 0.13 0.20 0.25 0.20
## PAGE1 0.05 0.05 0.15 0.21 0.10 0.22 0.12
## PITX1 42.52 41.47 40.26 20.32 37.80 39.42 49.02
## TRPC7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MAST4 2.66 2.14 2.25 0.65 1.50 1.85 1.35
## GPR116 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SDK2 0.49 0.69 0.83 0.15 0.62 0.63 0.57
## ADAM7 0.00 0.00 0.00 0.00 0.02 0.03 0.00
## NUP133 15.34 15.47 19.03 13.58 13.75 13.93 16.51
## NUCKS1 99.20 106.39 97.83 75.61 91.40 96.08 115.75
## VPS35 43.69 32.09 41.34 26.31 47.60 50.28 45.59
## DNAJA2 54.00 39.51 50.68 30.98 50.93 64.49 45.16
## BCL3 3.83 3.00 3.76 1.33 3.20 5.45 2.92
## KCNAB2 8.82 11.13 13.32 5.37 10.20 13.60 13.29
## ABCC9 0.02 0.02 0.04 0.01 0.04 0.03 0.03
## GAL 264.84 244.04 211.24 246.90 238.94 225.68 200.78
## CLEC2D 1.20 1.18 2.31 1.43 2.50 2.01 1.99
## FUNDC1 30.65 28.19 29.93 31.89 28.07 30.17 26.89
## MAOB 38.61 50.62 67.01 17.98 35.01 20.43 40.66
## RORA 1.39 1.57 1.73 0.39 1.96 1.86 1.54
## DRD4 0.49 0.35 0.25 0.35 0.45 0.32 0.63
## TGFBR3 0.80 0.68 1.05 0.39 0.69 0.86 1.00
## KIAA1107 0.24 0.13 0.34 0.17 0.46 0.49 0.24
## PLA2G10 0.05 0.08 0.00 0.00 0.03 0.03 0.04
## HES2 4.71 3.48 4.05 2.81 5.62 9.69 3.63
## ATP1B3 254.13 463.94 355.83 408.56 270.18 182.07 300.89
## NEDD4 4.53 2.37 5.25 1.38 3.90 4.32 4.17
## PIGB 5.55 4.08 5.39 3.46 4.69 3.39 3.72
## MAPK6 14.77 7.02 13.64 6.42 15.39 25.17 14.29
## GNB5 5.65 10.09 10.06 3.22 6.39 5.40 8.11
## RAB27A 7.18 5.46 7.11 3.08 6.22 6.69 6.05
## CECR5 39.48 44.87 41.28 34.06 30.43 33.70 40.48
## UFD1L 90.58 111.66 100.33 104.37 101.06 88.25 110.98
## LRP6 3.57 3.40 4.98 1.51 3.82 4.34 3.51
## GUCY2C 0.01 0.03 0.01 0.01 0.02 0.01 0.01
## SCT 0.98 0.12 0.00 0.79 0.62 0.76 0.30
## PHRF1 24.76 16.30 21.33 15.14 22.55 22.17 20.54
## IKBKAP 16.07 14.40 21.23 10.50 12.66 13.05 16.30
## NUCB2 65.19 62.35 74.85 85.88 69.08 65.31 64.03
## PFN2 174.50 116.06 197.28 132.55 170.32 169.84 156.78
## PTPN3 8.85 5.78 8.67 5.14 8.10 13.16 7.52
## SPTB 1.57 0.84 1.17 0.34 1.30 0.90 1.13
## DAPP1 0.04 0.00 0.00 0.05 0.11 0.08 0.00
## FGF10 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SLC44A1 8.91 10.18 15.67 4.95 9.31 7.28 10.85
## TMEM260 5.88 3.99 6.59 3.18 6.43 6.17 5.28
## SMG6 19.47 14.01 15.40 15.75 23.36 21.83 19.90
## EXOC5 14.36 10.80 18.77 4.66 11.56 10.96 12.03
## CLTCL1 1.28 1.58 1.37 1.32 1.54 0.81 1.72
## FGF22 0.28 0.46 0.25 0.11 0.55 0.07 0.34
## FSTL3 19.26 29.96 31.43 19.14 16.39 16.02 24.48
## DGCR2 22.07 20.94 23.58 16.78 25.41 23.29 28.18
## RNF126 45.33 55.05 58.21 21.05 42.94 31.85 47.16
## MNT 4.47 5.23 5.06 1.85 4.71 6.98 5.46
## ZXDC 15.63 12.24 17.10 11.55 16.44 10.76 15.32
## JMJD6 35.74 35.83 31.41 48.91 30.91 30.61 30.56
## POLB 23.46 21.21 21.69 21.79 21.43 31.05 18.60
## ST6GALNAC1 0.00 0.00 0.00 0.00 0.02 0.00 0.00
## WIPI1 20.26 20.26 23.72 29.36 31.48 37.04 30.80
## FRMPD1 0.10 0.20 0.33 0.11 0.20 0.13 0.18
## GBA2 34.93 29.23 38.04 16.89 41.12 30.43 36.41
## NDST1 8.39 6.41 6.60 2.65 7.19 9.96 7.25
## ASNS 82.97 94.61 84.27 289.31 150.84 148.24 160.98
## AP3M2 8.99 5.70 9.41 3.73 6.82 6.92 8.30
## CNGB1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ST6GALNAC2 0.89 1.43 1.27 0.56 1.60 0.96 1.07
## CHAT 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PABPC1 954.37 689.68 890.03 1232.72 1041.90 1065.28 1034.17
## TESK2 0.29 0.64 0.67 0.34 0.56 0.59 0.58
## C16orf80 39.48 30.82 39.99 29.73 33.70 35.57 31.85
## CSNK2A2 55.14 42.84 46.18 36.39 52.78 61.32 48.69
## PTPN21 3.64 2.84 4.99 1.95 4.37 4.69 3.81
## EIF2B3 37.21 32.52 32.61 34.76 29.62 29.05 33.70
## CAMK2A 0.02 0.00 0.00 0.01 0.00 0.00 0.00
## TCOF1 87.01 68.37 87.27 35.88 67.57 51.85 71.69
## CDC42 133.82 106.29 126.14 79.97 127.53 158.82 127.41
## OSBPL3 15.66 18.06 30.92 9.83 18.99 15.50 18.36
## EPHA8 1.93 2.88 2.78 1.15 1.47 1.29 1.75
## SLC12A3 0.08 0.01 0.12 0.00 0.04 0.03 0.05
## RAD18 15.02 7.36 12.37 4.51 11.22 12.89 12.19
## ATP2B1 8.85 7.08 8.87 4.73 7.11 6.10 9.48
## TRPM5 0.00 0.02 0.03 0.01 0.02 0.01 0.02
## NCK2 16.73 17.16 21.90 10.34 19.80 14.91 21.01
## MAP4K4 35.89 28.11 32.36 11.36 28.29 32.03 30.91
## MGAT4A 1.89 2.69 3.22 1.65 2.51 1.85 2.22
## RPL31 3816.52 4361.65 3307.54 4889.98 4056.10 4007.60 3749.14
## WDR1 162.98 101.43 114.78 95.33 127.51 208.74 131.01
## SNX13 8.76 6.02 10.02 2.80 7.82 11.15 8.41
## MS4A12 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ARHGAP10 7.15 6.04 6.98 3.94 6.49 6.07 6.99
## RPS6KA2 3.07 2.38 3.01 1.95 3.75 3.91 3.61
## ING3 9.38 9.26 12.84 3.61 7.67 9.51 9.01
## VASH1 1.81 2.12 2.37 0.72 1.55 0.89 2.17
## LMCD1 2.03 2.12 2.52 0.88 1.17 2.02 1.94
## WBSCR22 214.58 169.97 177.20 197.73 173.48 179.50 173.67
## SEL1L 15.93 9.83 16.10 12.97 14.91 21.09 13.92
## TRIP13 63.59 36.65 62.36 28.62 50.49 43.40 51.51
## ATP6AP1 55.62 57.40 61.00 43.85 56.94 54.54 61.98
## TCF3 42.90 41.67 56.26 35.00 48.87 33.85 51.04
## TRIB2 15.42 19.24 27.09 8.92 16.00 11.87 16.93
## DAZAP1 139.66 169.23 183.98 101.16 146.29 101.56 160.98
## MBD3 43.38 68.92 58.96 45.50 42.69 26.59 54.87
## PRLH 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## HLTF 0.19 0.16 0.14 0.31 0.25 0.19 0.25
## FAM50A 87.99 129.88 123.62 116.68 104.65 61.06 121.88
## FAM3A 46.08 48.02 50.97 40.90 47.18 37.52 54.92
## CPSF1 45.70 56.63 67.59 34.80 47.96 29.42 53.59
## MYO3B 0.14 0.22 0.30 0.05 0.13 0.13 0.14
## CYBRD1 34.20 24.51 44.17 24.41 40.20 43.55 36.95
## CDH19 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PDCD2 109.71 102.56 106.92 126.46 105.49 90.92 111.38
## SLC6A15 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## RDH11 32.58 34.46 39.84 26.14 37.64 44.28 32.72
## PRKACA 30.87 29.29 43.32 10.47 37.52 32.89 37.14
## LPHN1 4.21 6.47 7.08 1.18 3.40 2.32 3.81
## SPP2 0.00 0.00 0.00 0.00 0.00 0.30 0.04
## ACTN1 318.90 179.75 254.35 78.61 272.65 313.80 277.84
## ZFYVE26 4.53 4.21 5.67 2.18 4.56 5.06 5.87
## RPS6KA6 0.26 0.34 0.63 0.10 0.29 0.45 0.47
## EPN2 10.15 7.46 9.10 4.34 9.59 11.46 9.93
## PTPN18 50.92 41.52 56.80 27.32 57.69 47.39 57.65
## LIMS2 0.74 1.15 1.07 0.99 1.09 1.83 1.15
## ASIC4 0.07 0.10 0.09 0.45 0.16 0.16 0.13
## SPEG 2.46 3.78 4.57 2.65 4.52 2.72 3.69
## LNX1 0.30 0.21 0.35 0.10 0.50 0.60 0.25
## ALDH3A2 29.16 16.53 28.42 15.89 33.92 41.70 30.52
## TFRC 215.43 146.72 186.17 106.07 149.73 269.58 186.96
## SREBF1 20.32 37.36 40.45 14.71 27.59 20.97 45.00
## TRPC5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## AFF4 9.42 7.09 10.10 4.23 10.91 14.43 8.95
## UBE2D1 15.81 7.59 17.43 12.33 19.24 23.83 13.90
## MPP5 14.62 7.27 12.86 9.89 11.86 13.33 14.54
## RHOBTB1 0.81 0.71 0.92 0.36 1.14 1.17 0.49
## SMC1A 22.62 25.19 36.82 6.68 18.76 22.50 29.34
## HSD17B10 226.27 225.87 208.96 327.20 204.25 185.12 232.32
## MARK2 14.80 13.49 15.69 3.99 12.82 15.40 12.88
## HMMR 14.58 10.71 25.30 2.73 14.67 15.03 12.38
## CHFR 9.47 7.84 7.96 3.89 7.75 10.23 9.35
## TRHDE 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## P4HA2 65.06 64.45 61.94 55.99 53.13 44.66 61.91
## FCGR2B 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## NFATC3 6.18 7.79 9.58 2.80 6.95 7.79 7.00
## TRNT1 20.07 12.51 17.82 11.24 13.91 20.53 12.29
## ACADVL 332.56 420.14 481.46 283.30 264.78 183.11 293.52
## STK10 18.40 16.52 16.77 8.66 16.26 18.44 13.72
## FBXW11 16.78 12.83 18.18 10.64 14.77 20.34 15.58
## ACAP1 5.88 5.12 5.54 8.82 9.07 8.17 4.86
## CRMP1 16.33 17.74 17.83 9.01 14.50 17.83 16.40
## EVC 0.12 0.12 0.04 0.01 0.04 0.08 0.02
## DERL2 125.11 100.25 107.45 107.90 115.58 110.11 94.85
## SIDT1 0.17 0.07 0.15 0.02 0.14 0.29 0.06
## NDE1 18.11 16.30 21.30 2.33 14.19 17.12 17.53
## MRVI1 0.58 0.82 1.57 0.17 0.38 0.66 0.50
## TMEM38A 2.94 8.94 7.12 2.81 2.83 2.98 5.71
## AP1M1 29.46 28.00 29.47 16.17 31.45 31.45 32.81
## PVR 75.15 37.17 43.26 34.60 57.68 77.00 56.52
## IKBKG 29.79 22.31 25.04 28.25 33.21 31.97 34.50
## XRCC1 17.79 23.04 32.51 4.97 16.58 10.31 20.85
## SCARB1 42.87 42.71 48.03 24.55 34.38 31.01 36.67
## CYP2W1 0.08 0.46 0.32 0.10 0.27 0.19 0.14
## MCM2 85.62 83.73 97.72 39.70 67.68 72.16 100.40
## MOV10L1 0.04 0.12 0.04 0.15 0.05 0.19 0.05
## PANX2 4.75 4.59 4.28 4.40 5.23 5.50 5.46
## SELO 18.32 20.60 17.60 21.34 20.92 18.37 22.89
## TP63 0.00 0.00 0.00 0.01 0.01 0.00 0.00
## ALPK1 0.79 0.32 0.68 0.37 0.59 0.74 1.02
## LLGL2 32.82 52.19 52.60 39.19 42.41 31.25 48.41
## PDE8A 15.17 13.45 20.48 10.17 16.45 13.09 16.31
## CLCN4 0.82 0.62 0.90 0.25 0.74 1.30 0.84
## NLE1 36.95 30.06 30.77 16.49 25.01 30.22 29.90
## SDHA 72.89 138.18 111.81 94.48 85.05 54.22 94.51
## SMARCE1 151.73 99.68 155.86 60.23 147.77 148.19 137.87
## FNDC8 0.12 0.15 0.08 0.02 0.32 0.19 0.06
## GSDMB 1.59 1.84 3.43 1.65 3.25 2.35 2.32
## KDM5A 7.64 6.24 9.49 2.63 9.21 11.69 6.24
## ADAM11 0.69 1.09 1.07 0.40 1.05 0.78 0.99
## PPP2R3A 3.06 1.86 2.89 1.14 3.04 3.63 2.82
## FERMT2 13.20 7.95 12.84 7.28 11.19 11.86 10.81
## ABCB11 0.00 0.00 0.00 0.00 0.00 0.02 0.00
## DHRS9 0.06 0.00 0.01 0.00 0.07 0.00 0.00
## CD5L 0.10 0.00 0.00 0.00 0.00 0.03 0.00
## PTGS2 0.19 0.19 0.37 0.04 0.23 0.67 0.09
## IGF2BP2 25.11 21.60 30.64 12.42 25.05 24.88 26.90
## MAP3K13 56.68 34.07 47.89 34.82 61.13 65.33 48.88
## ST6GAL1 1.73 3.59 4.43 1.19 1.87 2.67 1.93
## TBX21 0.08 0.04 0.05 0.06 0.11 0.34 0.06
## FRY 0.75 0.16 0.93 0.22 0.35 0.24 0.58
## PICALM 84.70 49.20 83.15 35.68 91.22 104.20 79.96
## NSF 23.49 15.70 19.88 11.93 18.34 25.05 20.32
## GLI2 1.65 0.92 1.98 0.48 2.26 1.85 1.58
## CLASP1 8.92 6.11 9.42 1.94 8.67 8.32 7.38
## MRPS34 142.02 187.17 174.77 132.82 130.81 106.12 146.31
## NOTCH3 0.07 0.10 0.11 0.06 0.24 0.32 0.22
## CLNS1A 168.36 166.94 185.35 165.76 143.89 129.61 159.02
## PPP2R2C 7.62 7.93 10.39 6.37 10.33 12.37 10.67
## TEAD2 8.78 17.38 19.09 5.42 9.89 7.99 12.01
## EED 31.87 26.35 31.25 27.05 25.74 21.18 25.48
## CDHR2 1.29 2.37 1.77 0.66 1.60 1.26 1.13
## SNCB 0.36 0.35 0.21 0.26 0.37 1.06 0.29
## TSG101 85.72 91.38 91.20 67.09 70.30 107.16 83.25
## C17orf85 23.36 16.85 22.49 11.90 20.88 23.55 20.21
## ATP2A3 3.01 3.68 5.01 1.28 2.50 2.44 3.28
## CA12 0.43 0.16 0.11 0.01 0.26 0.46 0.14
## MGLL 9.53 5.34 5.66 8.42 14.99 18.70 11.85
## NTN4 0.49 0.32 0.76 0.32 0.59 0.51 0.29
## BCS1L 77.87 63.55 71.99 49.95 74.43 70.07 76.93
## NUAK1 1.79 2.24 2.46 1.14 2.05 2.09 2.76
## DPP8 13.75 12.36 12.36 7.98 11.62 15.37 12.85
## SLC24A1 16.05 5.87 5.10 4.30 10.00 17.58 7.40
## ZNF532 2.04 0.74 2.20 0.46 1.71 2.23 1.56
## SCARF1 1.60 0.51 0.74 1.41 1.43 1.49 0.95
## LMAN1 16.81 10.87 19.64 9.43 16.07 19.91 14.68
## PTPLAD1 60.97 49.50 68.99 30.58 50.49 56.47 55.51
## IPCEF1 0.11 0.00 0.00 0.00 0.00 0.01 0.00
## ZZEF1 6.29 5.01 7.11 2.34 7.44 6.82 6.36
## NOX3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ENO1 1481.27 1552.69 1430.47 773.21 1090.35 1417.05 1498.62
## SLC12A1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## C19orf10 164.00 166.19 133.82 237.16 151.08 168.11 147.69
## ANO8 0.70 1.58 1.62 0.11 1.27 0.96 1.37
## TUBE1 5.55 3.64 4.27 5.35 5.38 5.83 5.73
## ARHGEF10L 3.03 2.76 3.52 2.17 4.19 3.31 4.19
## TXK 0.03 0.18 0.07 0.04 0.24 0.07 0.13
## WSCD2 0.00 0.07 0.00 0.00 0.00 0.06 0.00
## KCNQ2 13.66 7.59 8.91 5.94 11.49 12.76 8.36
## TACR2 0.16 0.16 0.22 0.08 0.10 0.13 0.06
## ACTR6 11.71 12.56 14.76 12.54 11.50 13.55 11.60
## TIPIN 51.45 34.41 45.43 36.09 36.12 35.52 40.63
## SRI 200.01 196.66 190.34 226.91 178.27 184.04 199.39
## EIF4G3 9.34 11.08 16.55 2.88 10.97 9.84 12.67
## NUP37 63.70 42.03 52.40 48.15 57.18 57.43 56.12
## SEMA3A 0.83 1.81 2.96 0.25 0.80 0.56 0.88
## GTSE1 8.87 8.53 14.08 1.93 8.11 4.76 7.31
## SEMA3C 0.10 0.06 0.14 0.01 0.10 0.15 0.04
## TTC38 6.81 6.90 7.16 3.09 5.50 5.80 7.87
## ACAT1 70.78 78.17 72.35 85.83 69.96 69.12 70.72
## GRAMD4 6.21 9.91 11.99 5.39 7.70 7.97 9.32
## CELSR1 9.87 8.73 8.98 6.80 10.68 10.33 7.96
## WNT8B 0.08 0.14 0.44 0.01 0.08 0.21 0.14
## ZNF638 54.02 45.34 52.95 49.28 59.01 39.50 46.28
## SLC25A40 10.53 6.93 15.12 4.11 12.34 10.76 10.04
## TIMM21 21.86 15.73 20.75 14.48 19.65 19.81 17.85
## ADD2 0.00 0.00 0.00 0.01 0.00 0.05 0.00
## FGF4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RASAL2 4.86 1.41 1.86 0.86 4.69 4.90 3.86
## VPS9D1 2.18 3.14 2.59 1.96 2.96 2.70 3.13
## ZNF37A 4.28 3.44 4.76 1.70 4.29 4.13 3.88
## MARK3 55.17 37.36 44.11 42.33 52.11 51.52 47.50
## SLC25A3 398.71 431.98 348.78 469.36 406.01 371.30 414.63
## FNDC3B 13.86 8.14 8.17 11.70 12.33 20.95 9.55
## FOSL2 12.00 10.92 12.60 8.16 14.72 17.10 16.64
## CACNG5 0.00 0.00 0.04 0.00 0.04 0.03 0.00
## CACNG4 0.13 0.95 0.91 0.18 0.47 0.34 0.52
## FRYL 4.11 2.80 4.08 2.54 4.14 4.81 3.11
## TMEM131 12.69 7.78 14.76 5.89 13.21 13.27 13.01
## FSCN1 94.65 42.26 48.61 39.33 77.53 146.08 63.88
## ACTB 6928.36 4581.56 4477.45 7767.39 6908.91 6940.34 5469.76
## MOCOS 1.10 0.79 1.09 1.10 0.71 0.84 0.90
## PLD1 3.81 2.69 3.23 2.90 4.09 4.01 3.30
## ATP12A 0.08 0.06 0.03 0.01 0.05 0.10 0.08
## WDR62 8.79 11.56 13.94 5.52 9.08 6.77 11.16
## DLG1 34.51 17.49 35.85 13.48 35.02 36.71 31.18
## RAB7A 227.91 167.88 225.90 150.90 274.36 283.03 253.67
## BCAP29 82.87 61.46 100.12 46.76 80.69 70.80 77.72
## SEC31B 0.37 0.31 0.30 0.22 0.38 0.22 0.41
## SART3 16.45 13.84 18.58 6.69 16.30 17.36 17.42
## ARHGAP15 0.00 0.00 0.00 0.00 0.00 0.03 0.00
## TUBA3D 0.09 0.05 0.05 0.03 0.05 0.29 0.04
## PAX2 0.18 0.14 0.20 0.16 0.29 0.30 0.09
## EXOSC7 102.52 92.01 85.00 83.48 88.99 97.41 88.92
## KIFAP3 7.48 5.42 4.76 3.65 5.56 7.29 4.98
## MKRN2 22.65 11.76 17.24 12.46 24.90 26.67 20.79
## MCM6 104.49 95.92 102.01 59.64 83.22 76.72 102.19
## REXO2 82.97 94.27 97.84 116.34 94.77 81.53 90.70
## RBM7 18.53 15.61 22.53 11.13 17.25 24.49 18.26
## RBMS2 6.08 4.94 8.07 1.77 5.67 4.37 6.05
## BAZ2A 14.78 15.33 18.70 6.04 15.73 17.96 16.81
## PTPN23 12.06 13.35 14.44 3.96 13.73 12.28 14.55
## MLH1 34.89 30.28 38.65 23.93 27.71 31.86 35.67
## UNG 91.64 83.73 111.69 73.28 75.35 66.89 94.95
## FMO4 0.62 0.22 1.00 0.26 0.41 0.54 0.55
## KLHL20 7.87 3.80 7.36 1.24 6.28 9.84 5.92
## RGS11 1.00 0.57 1.45 0.61 1.17 0.84 1.01
## SLC46A1 14.99 15.51 16.32 5.45 11.83 10.23 11.53
## PLXNA2 0.32 0.34 0.40 0.18 0.24 0.29 0.28
## SPAG5 15.09 15.77 24.13 2.53 11.96 8.03 14.34
## ANKRD13A 6.68 6.44 7.93 2.93 7.57 9.17 6.54
## TPD52 51.35 33.78 63.20 34.88 56.44 54.43 53.98
## ACACB 0.69 0.83 0.83 0.33 0.92 1.02 0.67
## TRAF4 76.48 41.81 53.73 55.69 72.89 74.72 62.56
## PAG1 0.52 0.89 0.68 0.04 0.43 0.78 0.76
## GPATCH1 7.71 6.81 9.32 3.63 7.77 5.94 7.23
## ICAM3 17.55 22.13 20.75 16.45 22.51 15.29 23.58
## NT5C2 25.39 18.40 19.29 12.57 26.08 31.13 24.05
## MCAM 35.89 32.85 45.22 10.09 34.35 25.01 39.55
## GPC4 5.63 5.33 9.13 2.29 5.78 5.41 5.90
## MBNL3 2.71 1.01 2.59 0.76 1.99 2.29 1.38
## CAMSAP3 7.26 10.36 10.25 4.92 8.15 7.24 8.46
## RAP1GAP 3.28 3.69 4.47 2.39 4.77 5.20 4.66
## XAB2 25.75 25.27 25.33 14.52 23.05 24.49 26.86
## ARHGEF1 98.57 97.20 99.76 96.50 97.41 62.29 105.26
## STXBP2 41.88 50.03 54.05 43.54 38.50 38.03 47.65
## MAP2K7 10.45 13.99 14.10 5.93 10.31 8.59 12.20
## NMRK2 0.05 0.05 0.05 0.00 0.08 0.02 0.09
## DGKD 6.03 5.16 6.59 3.31 6.53 6.29 6.32
## CTTNBP2 0.32 0.34 0.17 0.19 0.18 0.68 0.62
## ACTL6B 0.08 0.36 0.30 0.14 0.12 0.15 0.08
## RARB 0.01 0.14 0.09 0.02 0.07 0.05 0.03
## TOP2B 36.11 30.17 46.48 28.97 35.32 32.06 34.14
## TM9SF3 55.50 37.26 60.37 39.20 48.20 62.88 51.77
## NFKB2 39.78 22.96 25.84 16.63 28.91 27.91 29.67
## UBE2T 83.88 87.36 102.31 61.20 74.25 47.40 74.15
## PPP1R12B 0.74 0.80 1.21 0.32 1.00 0.44 0.87
## DNAJC10 43.34 28.86 46.00 22.65 42.35 42.59 38.61
## GTF3C1 32.88 33.47 35.98 21.05 30.97 28.91 34.48
## IL4R 12.81 9.13 9.33 2.55 7.40 6.95 7.96
## USP33 8.81 8.20 12.06 8.11 11.10 10.47 9.90
## PAK3 0.00 0.00 0.00 0.01 0.00 0.00 0.00
## CAPN6 0.25 0.07 0.13 0.03 0.22 0.81 0.18
## DCX 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SNRPA 81.90 82.69 90.98 52.66 77.09 64.99 83.54
## SPAG6 0.03 0.01 0.00 0.00 0.00 0.00 0.17
## EXOSC5 40.48 58.73 57.04 40.19 41.82 30.98 51.54
## DYNC1I2 51.51 41.30 58.97 30.35 44.59 55.71 48.55
## APBB1IP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## LRCH4 30.36 34.11 44.39 18.45 39.41 33.32 39.19
## FAM76B 7.71 3.35 10.30 2.74 10.97 11.78 8.17
## SIRT6 24.70 18.50 17.70 22.59 26.04 24.95 25.22
## TYR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## POLD3 18.37 14.29 22.58 7.31 15.84 16.31 18.00
## ACTN2 0.10 0.00 0.04 0.06 0.19 0.24 0.00
## CAPZB 125.05 107.61 111.59 99.76 121.91 118.43 133.72
## GPR137B 12.07 10.52 13.44 11.58 13.12 18.86 14.71
## NAALAD2 0.11 0.06 0.26 0.49 0.23 0.12 0.11
## JADE1 4.57 5.14 6.19 3.55 4.96 5.05 5.13
## SLC25A43 11.23 6.99 12.13 4.47 10.35 10.02 8.51
## UBE2A 89.63 84.73 95.66 76.06 90.84 98.27 88.20
## FGFR1 26.68 21.01 27.25 12.62 26.02 25.52 32.38
## FKBP6 0.04 0.11 0.02 0.03 0.00 0.00 0.00
## GTF2I 63.57 86.40 109.49 31.79 69.02 48.19 72.56
## SMC1B 0.22 0.06 0.12 0.11 0.19 0.35 0.08
## FBLN1 1.98 2.20 2.33 0.83 2.12 2.17 1.61
## ITGA8 0.00 0.00 0.04 0.00 0.00 0.00 0.00
## CST7 173.46 200.74 188.56 183.48 206.97 185.12 208.82
## MAP2 0.32 0.28 0.21 0.19 0.52 1.11 0.33
## PIAS2 4.47 4.29 5.25 1.36 3.49 3.88 4.79
## AMPH 0.00 0.00 0.02 0.00 0.00 0.01 0.00
## ARAF 63.11 86.42 76.99 40.86 53.41 52.97 67.27
## MCCC1 18.07 24.82 25.16 14.54 19.25 15.13 24.55
## LAMP3 23.88 13.77 17.74 26.22 32.43 39.24 22.22
## FAP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NEBL 6.71 7.32 11.44 4.72 9.68 8.33 11.10
## ACER3 21.95 17.92 21.86 11.17 15.01 23.40 20.53
## UBE2K 62.44 58.62 59.40 53.06 55.24 49.74 57.91
## PIK3C3 8.01 10.76 9.33 5.02 7.37 9.28 7.32
## N4BP2 1.47 0.95 1.71 0.34 1.29 2.09 1.06
## C12orf5 30.88 24.06 26.35 21.71 26.32 32.34 23.04
## TULP3 8.94 8.18 11.15 5.17 9.19 10.69 10.88
## SYNJ2 15.85 20.56 16.59 11.74 14.43 13.06 17.40
## ADCY2 0.00 0.00 0.01 0.05 0.12 0.09 0.05
## PPP2R5C 143.88 108.96 133.49 130.58 153.75 155.92 143.25
## RBFOX1 0.02 0.00 0.00 0.00 0.00 0.01 0.00
## GNB1 150.43 152.30 170.63 85.76 129.19 151.59 163.58
## HOXA9 37.48 52.95 69.42 37.21 43.12 41.36 48.74
## EDN1 5.31 1.57 3.30 1.13 2.94 2.42 2.39
## MLLT10 6.05 4.72 7.22 3.34 6.20 6.19 6.63
## ZCWPW1 4.75 10.04 10.91 8.62 5.98 4.43 8.02
## ADCYAP1R1 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## FGF20 3.39 13.45 22.55 1.24 6.62 2.89 5.92
## P2RY10 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ITM2A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NRD1 55.72 52.13 56.80 62.17 57.57 51.80 62.90
## VDAC3 118.75 117.97 137.58 79.16 113.03 105.01 130.20
## PCM1 83.09 69.24 72.63 68.63 73.87 62.27 77.28
## TNRC6C 1.67 2.13 1.99 1.15 2.11 2.39 1.84
## CBFA2T2 4.36 3.72 4.53 3.49 5.38 5.08 4.01
## BRINP1 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## ITCH 18.45 12.22 20.04 12.76 16.28 19.70 18.40
## PKD2L2 0.01 0.05 0.00 0.00 0.01 0.01 0.01
## TP53INP2 3.58 5.27 5.76 1.58 3.74 5.88 4.18
## SDF4 132.34 147.32 151.40 97.83 119.48 127.44 141.14
## MYH7B 2.83 19.46 24.88 3.40 6.17 1.86 10.19
## BPIFB2 0.00 0.01 0.01 0.00 0.00 0.01 0.00
## TP73 3.18 5.96 8.75 1.24 3.77 1.82 4.21
## TOLLIP 32.38 32.17 28.90 31.68 31.88 37.91 37.71
## UBE2D4 38.30 33.78 40.97 25.25 40.29 41.07 41.66
## CLUL1 0.13 0.15 0.01 0.10 0.34 0.13 0.16
## RUNX1T1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CDH17 0.23 0.41 0.75 0.13 0.32 0.19 0.38
## THOC1 22.98 23.21 29.73 25.26 24.94 19.11 20.80
## FKBP7 5.36 6.54 7.45 4.63 5.94 4.95 5.59
## OSBPL6 4.85 4.28 5.11 3.52 4.86 4.72 5.40
## SLC1A3 1.39 1.48 1.77 0.72 2.17 1.56 1.24
## XRCC5 252.37 200.57 265.96 144.76 197.69 186.52 232.47
## LXN 0.00 0.00 0.03 0.00 0.00 0.00 0.00
## SP140 0.24 0.05 0.05 0.09 0.31 0.44 0.00
## MKNK1 14.23 13.47 15.59 13.16 14.91 13.98 16.18
## TNS1 0.46 0.39 0.49 0.14 0.43 0.80 0.56
## REXO1 13.46 11.26 14.34 5.97 12.42 15.31 14.07
## SAR1A 45.69 36.21 43.63 38.92 41.75 48.65 39.98
## CDC14A 1.66 0.58 1.56 0.86 1.66 1.98 1.51
## RAPGEF3 11.44 6.20 9.22 4.19 8.61 5.90 7.55
## CEACAM1 2.27 1.47 2.07 0.85 1.79 2.17 1.54
## SENP1 14.25 7.83 13.35 5.37 12.20 15.81 11.86
## DUSP13 0.18 0.25 0.12 0.20 0.15 0.14 0.20
## CIC 9.81 16.72 16.85 5.43 11.98 8.62 13.40
## LIPE 7.21 5.77 6.28 2.75 6.49 7.68 6.97
## FDFT1 35.16 31.35 31.21 43.22 40.85 76.42 45.39
## PAFAH1B3 52.52 106.99 93.65 72.62 64.36 38.12 79.18
## OPHN1 1.21 0.96 1.48 0.39 1.04 1.89 1.49
## AFM 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## KIF22 60.71 60.19 65.12 48.78 55.32 47.35 60.30
## SCGN 0.00 0.02 0.00 0.00 0.04 0.05 0.06
## LRRC16A 4.20 4.59 6.56 1.99 5.02 2.81 4.60
## PGM1 15.43 32.86 27.49 9.01 10.92 11.30 20.75
## DDX1 80.19 83.04 91.21 61.30 66.63 69.91 84.69
## DNM2 49.84 51.33 61.43 32.52 53.40 49.14 58.72
## EPB41L2 23.38 11.86 19.65 8.06 17.22 28.43 22.99
## RIMS1 0.01 0.04 0.05 0.00 0.01 0.03 0.01
## MOXD1 0.00 0.01 0.00 0.00 0.00 0.00 0.01
## STX7 12.04 7.62 12.74 5.37 13.71 14.06 10.38
## RABL2B 14.20 12.77 17.09 6.73 14.21 14.00 14.24
## KEAP1 59.33 86.10 75.97 99.35 66.55 58.80 74.55
## DDX43 0.00 0.00 0.00 0.02 0.00 0.07 0.00
## PTPRH 1.70 1.42 1.26 1.33 2.08 3.46 2.30
## DCT 0.06 0.05 0.06 0.03 0.00 0.02 0.03
## SLC35C2 57.40 59.32 60.52 29.27 55.33 61.47 49.73
## CRYBG3 7.69 4.13 6.53 3.50 9.00 8.74 6.99
## EPHA6 0.00 0.00 0.03 0.00 0.00 0.02 0.00
## SCTR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RFX3 0.44 0.38 0.48 0.16 0.30 0.56 0.36
## RIF1 10.50 6.02 11.75 2.62 8.60 10.02 8.17
## RAB21 34.62 20.64 32.22 13.48 29.11 40.95 27.58
## SLC4A4 0.14 0.05 0.07 0.04 0.08 0.27 0.09
## SMARCA2 20.59 15.74 26.49 11.03 22.89 24.64 20.84
## RDH8 0.02 0.00 0.00 0.00 0.05 0.21 0.00
## SESN1 2.66 1.86 2.68 2.35 2.63 3.60 3.04
## MID2 5.87 3.10 4.03 1.60 4.51 8.64 4.80
## PIH1D3 0.00 0.00 0.00 0.03 0.00 0.12 0.00
## COL5A3 0.83 1.13 0.86 0.31 0.78 1.07 0.74
## SRCAP 9.90 11.76 11.18 3.33 9.98 11.29 9.88
## KIAA0020 72.70 53.11 55.22 65.73 52.66 71.57 54.77
## CPB2 0.07 0.03 0.03 0.04 0.03 0.09 0.06
## CHRNA3 1.01 0.61 0.78 0.69 0.80 2.61 0.87
## KCNN2 0.03 0.08 0.08 0.03 0.07 0.11 0.11
## CNOT4 8.04 5.88 9.67 3.91 8.85 9.48 7.48
## PSEN1 36.55 31.63 37.61 24.03 39.40 47.37 38.11
## CPOX 11.03 8.06 13.99 9.30 11.62 11.37 11.66
## CLDND1 36.20 22.16 28.33 19.01 29.31 41.06 24.98
## MOK 6.59 3.87 5.12 4.62 5.74 3.85 6.87
## HSP90AA1 1734.16 1475.44 1604.25 2089.52 1489.37 2212.74 1692.85
## RBL1 15.66 6.95 13.12 4.96 13.83 13.78 12.40
## DLGAP4 36.66 33.71 36.30 16.05 32.31 36.76 30.58
## IGSF9B 3.14 4.58 3.83 0.51 3.12 2.08 4.14
## CFHR2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NDC80 19.71 25.92 38.91 12.94 17.54 10.00 18.16
## AP4E1 4.27 2.54 3.76 1.33 3.31 3.67 2.83
## RSBN1 2.11 1.71 1.75 1.09 2.45 1.83 1.71
## MAGI3 3.49 2.03 3.07 1.61 4.12 3.55 3.21
## CXCL2 2.70 0.42 0.55 0.27 0.74 0.92 0.55
## AFP 0.00 0.00 0.04 0.07 0.09 0.08 0.00
## COL4A4 0.20 0.19 0.32 0.11 0.31 0.22 0.25
## TCF7 29.54 39.48 50.97 10.54 34.51 23.41 42.91
## OSTM1 12.54 8.76 12.96 9.43 14.60 16.26 10.97
## CDH7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## IMPG2 0.00 0.00 0.00 0.00 0.00 0.02 0.00
## PCNP 84.11 52.74 85.93 70.23 85.42 79.79 81.53
## EXD2 11.86 11.23 14.61 4.69 14.05 12.26 13.35
## ARG2 23.98 55.71 45.70 19.31 31.25 31.64 32.79
## MEF2C 0.27 0.06 0.02 0.02 0.01 0.10 0.09
## PTPRC 0.00 0.01 0.00 0.00 0.00 0.01 0.00
## CACNA1S 0.00 0.00 0.00 0.00 0.01 0.02 0.00
## PKP1 0.63 0.59 0.71 0.10 0.38 0.51 0.37
## UBA5 41.03 23.81 36.01 29.49 30.85 42.79 33.03
## STK17B 2.98 1.36 2.54 1.18 2.80 4.78 2.66
## CDC14B 6.34 4.01 6.76 2.35 6.27 7.47 6.48
## ZNF510 3.66 3.09 4.11 0.87 3.67 5.07 3.01
## LRP2 0.25 0.57 0.80 0.07 0.16 0.17 0.29
## ZNF506 9.46 5.65 8.25 4.51 8.87 16.27 7.26
## JMJD4 24.04 22.14 19.75 8.78 16.30 18.11 19.29
## DUSP12 33.54 33.60 27.48 29.64 27.73 35.13 30.28
## AACS 10.16 12.46 13.04 9.01 10.44 10.37 11.87
## KIAA0141 33.32 27.50 33.48 15.84 31.07 30.85 30.90
## SLC13A1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CADPS2 2.25 3.69 4.83 1.65 2.68 2.30 3.13
## PCDHB4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PCDHA6 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## PCDHGA2 0.00 0.00 0.04 0.13 0.00 0.05 0.03
## HSPB11 96.97 109.61 109.79 149.27 105.11 78.25 104.29
## PHLPP1 0.68 0.77 1.29 0.24 0.64 0.70 0.77
## ATP8B1 0.39 0.49 0.46 0.28 0.44 0.73 0.41
## IL12RB2 0.36 0.23 0.16 0.10 0.25 0.29 0.44
## SMARCD3 13.42 13.28 16.54 7.12 13.29 13.11 13.65
## WDR70 19.72 25.77 21.52 26.73 20.05 12.04 19.71
## FYB 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## MPP4 0.16 0.08 0.12 0.08 0.11 0.07 0.12
## STRADB 28.61 18.91 24.04 19.66 31.11 27.57 28.28
## BZW1 292.71 165.14 246.54 190.75 249.85 321.49 236.48
## PGR 0.00 0.00 0.00 0.01 0.00 0.00 0.00
## C1QTNF3 0.31 0.32 0.57 0.05 0.26 0.18 0.18
## ME2 15.14 11.68 17.36 13.10 16.22 15.27 14.54
## C5orf22 13.52 6.66 12.77 8.77 15.33 17.25 11.39
## CCNT2 7.29 2.66 7.21 3.75 10.33 9.14 7.29
## FAM135A 1.76 0.85 2.37 1.24 1.46 2.02 1.09
## COL19A1 0.01 0.13 0.00 0.00 0.00 0.21 0.00
## EPB41L3 0.02 0.09 0.06 0.00 0.00 0.03 0.00
## COBLL1 2.63 1.22 1.90 0.61 2.83 3.83 2.20
## DLG3 10.46 11.10 16.87 2.80 7.92 12.42 10.07
## KCNK2 0.09 0.03 0.08 0.01 0.04 0.03 0.01
## SERTAD4 0.17 0.12 0.23 0.07 0.21 0.45 0.39
## TRAF5 3.58 1.95 3.47 1.20 3.08 3.17 2.81
## MRPL22 101.86 112.43 104.69 101.89 106.23 83.47 104.70
## GEMIN5 24.98 13.46 19.56 6.20 15.74 18.39 17.69
## OPRK1 0.13 0.02 0.05 0.00 0.05 0.12 0.03
## NFE2L1 64.12 58.22 72.73 32.58 57.66 83.25 68.09
## SEMA5B 0.01 0.00 0.05 0.00 0.00 0.00 0.00
## GSK3B 21.66 23.44 24.90 7.21 18.16 16.77 18.81
## ITGB5 76.18 100.38 117.12 42.82 85.52 70.49 107.92
## ERC1 3.28 3.68 3.95 1.11 2.70 4.08 2.92
## XPO1 58.31 59.32 92.69 37.03 57.49 45.49 56.54
## C4orf6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RNF13 40.74 34.97 46.67 32.85 47.38 52.06 44.37
## TRPM3 0.07 0.22 0.11 0.00 0.00 0.09 0.02
## PALB2 12.27 9.07 13.14 13.29 12.34 10.28 11.82
## DOPEY1 1.57 1.26 2.44 0.48 1.81 1.36 1.52
## LYRM2 44.01 35.31 41.81 19.78 32.39 36.58 35.16
## BCKDHB 11.42 10.73 13.06 6.20 12.77 12.41 11.90
## mRNA_R24 mRNA_R28 mRNA_R27 mRNA_R26 mRNA_R25 mRNA_R23 mRNA_R22
## TSPAN6 4.95 4.01 3.61 3.61 3.45 4.35 2.98
## TNMD 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DPM1 182.84 179.46 177.32 161.67 209.87 171.66 155.91
## SCYL3 3.49 3.81 4.87 5.07 3.90 2.99 4.27
## C1orf112 6.03 6.40 7.31 11.12 5.64 6.01 6.16
## FGR 0.44 0.74 0.69 0.00 0.55 0.02 0.41
## CFH 0.31 0.14 0.32 0.77 0.30 0.49 0.94
## FUCA2 42.15 38.20 38.09 29.32 37.02 26.14 35.56
## GCLC 172.71 136.24 223.35 395.42 282.33 209.92 353.38
## NFYA 6.49 7.13 8.48 8.85 6.81 6.16 6.34
## STPG1 9.47 10.37 14.05 8.32 11.17 6.45 11.37
## NIPAL3 9.00 10.37 10.46 9.58 8.63 6.31 7.20
## LAS1L 30.36 32.89 33.79 35.95 34.01 24.82 37.20
## ENPP4 0.45 0.24 0.12 0.18 0.39 0.34 0.28
## SEMA3F 28.39 23.97 29.11 18.01 18.99 17.39 17.14
## CFTR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ANKIB1 11.30 15.33 19.16 12.88 14.38 7.13 11.79
## CYP51A1 52.16 81.76 77.79 52.62 60.48 44.65 52.34
## KRIT1 15.81 15.49 17.51 20.89 15.98 14.21 16.84
## RAD52 4.97 4.90 5.40 7.44 3.07 4.15 3.90
## BAD 68.97 65.06 64.24 56.95 62.25 48.35 66.52
## LAP3 21.92 26.29 21.85 31.40 30.65 23.32 32.67
## CD99 95.12 84.71 99.73 87.25 94.45 74.27 92.92
## HS3ST1 2.80 4.19 5.81 1.50 4.81 2.97 3.26
## AOC1 0.01 0.00 0.00 0.00 0.00 0.00 0.00
## WNT16 0.04 0.00 0.09 0.00 0.03 0.05 0.00
## HECW1 0.00 0.00 0.00 0.03 0.00 0.00 0.00
## MAD1L1 41.13 44.46 48.55 52.18 44.18 37.31 60.15
## LASP1 43.93 48.36 50.99 51.50 47.93 31.78 50.42
## SNX11 16.80 18.30 18.80 20.35 19.65 11.31 24.88
## TMEM176A 0.00 0.00 0.00 0.00 0.00 0.00 0.18
## M6PR 54.72 61.31 67.27 57.72 61.58 41.69 64.78
## KLHL13 0.44 0.31 0.26 0.17 0.45 0.50 0.13
## CYP26B1 1.67 1.73 2.86 1.66 1.31 2.75 1.40
## ICA1 9.84 10.13 10.80 5.78 7.68 4.15 6.31
## DBNDD1 11.76 10.99 17.44 11.52 8.42 6.35 9.57
## ALS2 4.90 4.95 5.60 6.99 6.61 4.99 7.45
## CASP10 0.95 0.75 0.97 2.66 0.83 0.68 0.67
## CFLAR 25.73 28.37 25.96 27.11 32.52 20.43 26.86
## TFPI 0.15 0.11 0.16 0.00 0.08 0.04 0.11
## NDUFAF7 15.89 14.66 15.03 23.99 17.82 20.60 17.51
## RBM5 26.07 29.77 36.71 43.38 26.63 32.27 33.53
## MTMR7 0.22 0.30 0.28 0.52 0.33 0.63 0.40
## SLC7A2 0.13 0.21 0.17 0.06 0.18 0.09 0.25
## ARF5 149.37 129.85 136.73 168.98 147.71 119.97 173.35
## SARM1 1.14 1.87 2.64 1.87 1.00 1.68 1.07
## POLDIP2 68.49 67.14 71.64 80.83 66.92 52.05 82.96
## PLXND1 5.15 5.72 6.03 10.30 5.50 7.12 7.97
## AK2 299.97 324.85 307.23 209.69 286.23 204.43 280.38
## CD38 0.00 0.04 0.08 0.00 0.00 0.00 0.00
## FKBP4 97.19 106.76 111.51 101.30 100.91 72.89 96.16
## KDM1A 33.39 32.88 38.36 46.18 27.55 33.51 29.80
## RBM6 26.68 30.02 29.99 41.93 27.48 33.87 29.30
## CAMKK1 11.33 9.90 13.43 12.67 12.01 9.34 11.59
## RECQL 22.10 31.89 28.53 32.90 28.33 15.59 24.55
## CCDC132 8.62 8.70 8.95 7.74 8.55 5.96 9.77
## HSPB6 0.34 0.18 0.40 0.00 0.24 0.00 0.29
## ARHGAP33 2.03 1.44 2.46 2.77 1.39 1.77 2.30
## NDUFAB1 308.16 241.29 194.04 331.63 249.33 408.51 254.53
## PDK4 0.79 2.15 5.37 0.18 1.80 0.27 0.96
## SLC22A16 0.00 0.00 0.00 0.00 0.04 0.02 0.00
## ZMYND10 0.58 0.37 0.28 0.00 0.21 0.60 0.43
## ABCB5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ARX 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## SLC25A13 12.00 13.13 16.22 15.50 14.29 8.26 14.24
## ST7 11.52 12.67 13.42 12.83 10.96 7.70 11.50
## CDC27 25.88 30.14 31.71 24.64 29.30 14.15 21.16
## SLC4A1 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## CALCR 0.01 0.00 0.00 0.00 0.00 0.00 0.00
## HCCS 50.26 56.20 57.47 47.62 61.17 33.94 55.05
## DVL2 14.81 17.87 21.94 25.11 15.63 17.05 21.39
## PRSS22 28.03 65.48 53.60 15.94 34.10 17.05 29.39
## UPF1 32.96 35.93 38.88 49.31 38.68 29.58 39.00
## SKAP2 6.44 6.95 6.86 9.85 6.96 4.06 6.19
## SLC25A5 605.07 600.51 607.24 430.68 548.43 394.17 529.04
## CCDC109B 14.09 10.30 9.93 13.62 14.76 12.23 10.64
## HOXA11 10.39 10.53 13.82 12.76 11.03 6.59 11.00
## POLR2J 118.02 93.11 106.83 97.80 110.36 112.69 135.60
## DHX33 12.60 15.97 18.86 13.26 13.39 10.23 12.33
## MEOX1 0.02 0.01 0.00 0.00 0.01 0.00 0.00
## THSD7A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## LIG3 10.02 12.03 12.02 13.18 10.59 6.31 10.16
## RPAP3 21.37 23.01 19.87 30.27 25.68 23.42 24.27
## ACSM3 1.66 2.10 2.07 2.36 2.09 3.02 1.37
## AC004381.6 3.12 2.77 2.11 1.72 4.29 2.45 2.52
## CIAPIN1 67.95 73.04 70.29 76.19 67.31 57.81 80.57
## FAM214B 20.01 25.51 33.81 19.86 19.89 12.65 20.90
## COPZ2 6.11 6.37 6.27 6.67 5.61 5.69 4.32
## PRKAR2B 0.01 0.06 0.00 0.00 0.02 0.00 0.07
## MSL3 12.27 12.07 12.46 14.47 11.97 10.65 11.62
## CREBBP 4.12 5.23 6.77 8.34 5.07 4.36 6.68
## BZRAP1 0.83 0.98 1.20 0.78 0.85 0.20 1.37
## MPO 0.10 0.12 0.10 0.00 0.19 0.07 0.19
## PON1 0.00 0.00 0.00 0.00 0.03 0.00 0.44
## GCFC2 25.05 28.19 20.73 32.44 32.58 24.56 25.20
## WDR54 36.75 28.15 26.65 36.76 27.44 37.09 30.10
## CROT 5.27 4.68 4.03 6.65 6.63 5.17 5.47
## ABCB4 0.00 0.00 0.19 0.00 0.00 0.00 0.41
## KMT2E 7.88 7.38 11.46 11.94 8.70 7.11 8.10
## RHBDD2 33.89 39.33 47.84 36.56 35.90 20.60 42.77
## SOX8 0.11 0.15 0.23 0.00 0.17 0.10 0.11
## IBTK 19.33 23.58 25.37 19.69 24.60 14.44 19.00
## ZNF195 15.38 15.15 17.75 21.49 17.76 18.05 15.61
## MYCBP2 9.91 12.96 13.25 16.00 10.68 7.22 11.71
## FBXL3 18.04 20.62 23.29 24.30 21.16 13.43 20.68
## ITGAL 0.00 0.00 0.00 0.00 0.00 0.00 0.03
## PDK2 7.90 7.79 10.09 6.94 6.20 3.19 6.49
## ITGA3 253.24 308.83 337.22 299.90 251.52 222.76 338.58
## ZFX 3.19 3.07 4.47 5.22 3.61 3.07 3.18
## LAMP2 42.26 45.22 50.31 37.89 51.37 23.46 43.21
## GGNBP2 60.76 60.74 65.06 76.33 62.91 56.59 60.94
## ITGA2B 0.32 0.92 0.56 0.00 0.32 0.22 0.33
## ASB4 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## GDE1 44.61 50.15 67.04 37.68 45.86 34.88 49.08
## C19orf60 30.17 23.96 22.22 43.28 35.48 41.54 44.44
## CRLF1 5.84 2.03 5.84 4.12 5.43 6.93 4.56
## OSBPL7 2.93 2.51 2.02 4.06 1.79 3.40 1.95
## TMEM98 1.29 1.09 0.62 2.07 1.23 2.07 1.01
## YBX2 9.93 9.93 10.61 10.64 8.27 7.20 7.64
## KRT33A 0.00 0.00 0.00 0.15 0.00 0.00 0.00
## ABCC8 0.02 0.00 0.00 0.04 0.06 0.00 0.00
## CCL18 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CCL3 0.00 0.00 0.00 0.26 0.02 0.00 0.09
## SYNRG 2.30 3.29 3.29 3.73 3.28 1.27 2.78
## CACNG3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMEM132A 24.23 22.17 29.47 18.56 24.30 14.79 21.78
## AP2B1 37.83 43.12 40.32 37.61 43.42 24.74 42.56
## TAC1 0.42 0.03 0.09 0.60 0.24 0.49 0.67
## ZNF263 20.94 28.69 34.34 31.91 23.95 15.71 27.70
## CX3CL1 0.54 0.83 0.90 0.21 0.66 0.00 0.38
## SPATA20 15.03 14.29 15.68 27.20 12.76 18.76 17.21
## CACNA1G 0.09 0.05 0.16 0.05 0.04 0.04 0.07
## TNFRSF12A 449.59 557.27 449.70 461.74 566.62 397.94 690.43
## DLX6 1.75 1.30 1.73 2.39 1.02 1.31 0.74
## MAP3K9 2.83 4.72 4.34 5.31 3.52 2.98 3.84
## RALA 46.21 58.07 54.67 35.20 56.13 27.46 46.62
## BAIAP2L1 36.71 47.66 52.50 39.88 43.81 30.07 45.05
## KDM7A 2.40 3.27 3.67 1.74 3.15 1.46 2.68
## ETV1 0.30 0.28 0.25 0.82 0.32 0.08 0.39
## AGK 10.32 10.83 10.73 13.32 9.43 8.69 11.34
## ALDH3B1 4.18 5.30 6.93 2.15 3.77 2.51 3.67
## TTC22 5.94 4.98 6.96 5.10 4.62 3.56 5.77
## PHTF2 8.29 8.51 8.31 6.81 7.32 5.68 6.53
## CCL26 0.24 0.11 0.13 0.00 0.15 0.00 0.26
## FARP2 5.82 5.17 6.19 8.60 5.26 6.20 7.60
## USH1C 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GGCT 122.30 129.98 111.09 102.01 158.04 89.63 132.53
## DBF4 21.55 25.00 25.96 27.41 24.49 21.20 19.96
## TBXA2R 0.02 0.01 0.04 0.02 0.04 0.12 0.02
## IFRD1 52.17 75.49 80.47 49.56 65.24 36.95 61.82
## LGALS14 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## COX10 13.91 15.61 17.33 13.22 16.56 8.12 16.22
## GTF2IRD1 62.90 51.61 71.06 64.13 49.27 33.63 58.35
## PAF1 34.54 34.40 41.88 38.81 35.07 29.91 36.36
## VPS41 10.32 12.53 11.77 12.34 11.85 8.87 12.77
## ARHGAP44 0.42 0.31 0.42 0.16 0.28 0.29 0.32
## ELAC2 37.50 40.11 42.27 62.74 32.06 47.05 41.11
## SCIN 0.06 0.03 0.03 0.00 0.05 0.00 0.07
## ARSD 4.83 6.02 6.54 2.52 6.40 4.79 7.07
## PNPLA4 25.06 16.14 18.62 13.79 19.93 22.45 25.66
## MYH13 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ADIPOR2 30.08 41.38 42.24 29.26 34.83 17.75 33.82
## CDKL3 7.65 6.73 4.66 5.64 7.48 4.45 6.51
## UPP2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PRSS21 16.66 21.57 19.70 12.73 18.22 13.02 12.66
## MARK4 10.85 13.88 18.76 6.42 10.82 3.91 9.08
## PROM1 0.00 0.00 0.00 0.00 0.00 0.00 0.04
## CCDC124 105.19 105.09 105.49 136.09 116.56 95.96 151.51
## CEACAM21 0.00 0.00 0.06 0.00 0.21 0.00 0.22
## PAFAH1B1 86.53 87.89 88.77 71.41 100.05 56.47 87.62
## NOS2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DNAH9 0.03 0.08 0.03 0.15 0.05 0.14 0.05
## KIAA0100 17.96 23.33 25.44 36.48 18.25 17.59 23.55
## SLC13A2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GAS7 0.08 0.11 0.15 0.00 0.06 0.04 0.02
## TRAPPC6A 12.72 11.50 11.25 9.50 14.02 7.77 11.86
## MATK 5.10 3.09 4.36 8.33 3.86 3.37 3.32
## CEACAM7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CD79B 0.02 0.09 0.22 0.00 0.00 0.00 0.03
## SCN4A 0.02 0.01 0.01 0.00 0.00 0.00 0.00
## ST7L 9.09 10.73 9.23 19.04 12.36 9.98 11.05
## TKTL1 0.00 0.00 0.02 0.00 0.10 0.00 0.03
## PAX6 1.40 2.11 1.90 2.20 1.09 0.43 0.76
## RPUSD1 23.90 24.78 28.32 40.10 23.36 28.56 34.14
## RHBDF1 27.80 28.70 38.11 49.75 28.82 34.67 33.50
## LUC7L 35.40 37.12 42.31 46.94 30.47 40.52 36.75
## CACNA2D2 0.16 0.11 0.27 0.00 0.08 0.03 0.14
## BAIAP3 0.72 1.03 0.61 3.34 0.66 0.46 0.81
## TSR3 66.83 65.73 66.03 66.77 70.62 48.08 77.02
## PIGQ 10.20 9.90 10.54 22.60 10.76 13.96 16.99
## CRAMP1L 5.45 6.05 8.45 8.26 5.54 5.43 6.26
## TEAD3 15.44 14.58 19.48 21.26 17.35 13.33 17.57
## SELE 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DNAJC11 29.09 24.17 30.34 47.23 26.28 30.73 33.36
## FMO3 0.00 0.00 0.00 0.00 0.00 0.00 0.32
## MYLIP 2.37 3.28 4.11 2.84 2.80 1.18 2.58
## NOX1 0.10 0.10 0.08 0.32 0.15 0.27 0.16
## E2F2 0.77 0.61 0.69 2.46 0.63 0.86 0.74
## PSMB1 364.48 328.43 301.01 360.22 372.33 370.82 379.11
## SYN1 2.47 3.02 5.82 0.99 3.03 0.84 2.34
## JARID2 9.14 13.57 16.34 8.26 12.01 7.43 10.25
## CDKL5 0.04 0.18 0.36 0.08 0.05 0.20 0.05
## CAMK1G 0.03 0.00 0.01 0.10 0.02 0.00 0.06
## CDK11A 31.44 35.45 49.05 64.73 38.04 44.47 56.12
## NADK 34.18 43.55 45.80 52.43 35.05 42.78 49.54
## TFAP2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TFAP2D 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DLEC1 0.04 0.06 0.07 0.11 0.04 0.06 0.14
## CYTH3 11.93 20.80 15.42 29.88 16.80 16.80 18.81
## ADAM22 0.21 0.04 0.04 0.07 0.11 0.11 0.06
## SYPL1 123.51 136.11 162.43 89.33 153.56 64.67 107.37
## CYB561 41.69 49.80 66.09 34.70 35.14 24.51 37.06
## SPAG9 20.19 28.37 33.57 22.28 28.23 17.36 28.71
## CELSR3 1.49 1.73 2.37 1.42 1.83 1.24 2.07
## AASS 0.89 1.36 0.79 0.89 0.91 0.48 0.69
## PLEKHG6 2.31 2.73 3.05 1.37 1.42 0.75 1.32
## SS18L2 30.81 28.80 25.99 39.49 26.17 54.67 25.00
## MPND 5.96 5.52 5.91 5.91 4.61 5.06 5.04
## MGST1 537.70 372.70 441.64 404.76 508.77 487.90 524.56
## CRY1 8.45 13.82 14.14 10.82 12.43 8.20 11.69
## PGLYRP1 0.04 0.00 0.04 0.00 0.10 0.00 0.00
## NFIX 15.13 17.10 24.51 14.49 14.28 8.13 13.51
## ST3GAL1 4.73 7.94 8.84 2.56 6.24 2.84 5.72
## MMP25 0.17 0.12 0.27 1.43 0.30 0.37 0.61
## IL32 35.96 47.56 54.09 26.28 50.97 16.71 39.89
## PKD1 20.60 22.19 30.77 46.59 21.97 25.58 39.42
## MAPK8IP2 0.60 0.32 0.53 0.66 0.55 0.27 1.30
## MED24 54.31 48.90 56.31 66.96 42.51 56.95 43.85
## RHOBTB2 4.74 5.07 4.15 10.54 6.05 5.92 6.64
## HEATR5B 2.84 3.40 4.60 4.73 2.75 2.32 3.53
## SEC62 61.01 79.94 102.06 66.02 88.65 40.48 66.38
## RPS20 2488.86 2330.34 2088.58 2690.85 2297.47 4021.06 2164.30
## CSDE1 131.73 146.92 183.98 146.87 134.25 91.74 121.37
## UBE3C 19.48 24.16 31.47 29.84 22.59 14.73 24.09
## REV3L 8.40 9.26 11.63 14.58 11.21 7.66 9.84
## TENM1 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## PAX7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MASP2 0.36 0.30 0.46 0.40 0.26 0.84 0.32
## IYD 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## FAM76A 6.20 7.07 5.69 3.10 6.80 4.25 5.41
## TRAF3IP3 5.89 5.00 7.68 3.05 6.55 4.21 5.87
## POMT2 6.15 6.08 5.64 20.57 5.68 11.52 8.30
## VTA1 45.01 43.59 47.09 40.81 52.96 25.39 43.90
## MLXIPL 3.63 2.81 4.94 5.40 3.12 3.13 5.89
## BAZ1B 18.59 20.75 25.82 27.17 19.62 17.15 22.63
## RANBP9 23.27 25.94 30.65 27.44 24.39 15.67 25.53
## ETV7 6.67 6.39 7.24 3.10 6.00 2.16 4.23
## SPRTN 7.71 7.78 10.22 6.57 8.51 7.00 7.14
## METTL13 22.35 25.19 24.86 34.17 28.62 17.97 27.10
## DYRK4 23.53 19.03 18.98 18.87 11.67 21.14 9.94
## ZNF207 89.26 92.31 102.64 94.05 94.38 79.96 109.12
## UQCRC1 172.69 161.29 175.00 225.70 135.36 138.30 174.25
## STARD3NL 23.10 22.26 19.76 18.91 20.77 16.35 18.81
## CD9 242.02 252.33 275.51 144.59 231.45 176.11 182.02
## HHATL 0.00 0.00 0.05 0.00 0.00 0.00 0.05
## NCAPD2 16.84 19.12 21.71 20.10 19.60 14.68 18.60
## IFFO1 1.18 0.99 0.72 1.25 1.21 1.14 1.68
## GIPR 0.45 0.26 0.31 1.30 0.17 0.23 0.09
## PHF7 3.78 5.12 5.10 3.53 5.60 3.52 4.88
## SEMA3G 0.01 0.01 0.05 0.00 0.02 0.00 0.02
## NISCH 12.42 12.51 15.55 23.03 13.13 14.06 17.83
## STAB1 0.16 0.02 0.00 0.00 0.01 0.00 0.03
## FUZ 5.90 5.10 6.42 6.72 3.53 3.74 3.33
## SLC6A13 0.07 0.03 0.00 0.00 0.06 0.00 0.44
## IDS 15.24 15.62 15.06 15.41 18.14 8.90 15.09
## PRSS3 69.07 83.39 89.51 50.69 43.40 66.88 55.50
## ZNF200 7.26 8.51 8.21 9.53 8.64 5.48 9.41
## CD4 0.05 0.00 0.03 0.00 0.00 0.09 0.13
## LRRC23 7.15 7.09 5.86 5.08 6.75 6.70 6.16
## BTK 0.03 0.00 0.09 0.00 0.01 0.00 0.00
## HFE 0.80 0.43 0.96 1.12 0.50 0.60 0.60
## SCMH1 10.74 12.20 15.38 7.61 9.13 9.71 11.68
## FYN 2.98 5.29 5.12 4.55 3.44 2.69 3.34
## HIVEP2 4.76 5.90 6.27 5.90 5.97 4.16 6.40
## FMO1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TCEB3 18.99 23.14 22.59 21.66 21.75 16.39 21.99
## LYPLA2 71.50 75.48 80.21 99.11 73.38 66.37 91.84
## CLCN6 5.18 9.12 8.91 8.08 6.50 4.10 7.83
## MRC2 7.71 6.26 8.32 5.18 7.06 5.28 5.64
## NME2 966.99 1022.71 808.54 724.83 736.35 990.18 904.66
## SLC6A7 0.04 0.01 0.02 0.00 0.02 0.00 0.01
## TSPAN9 4.47 5.21 5.56 9.68 6.51 3.47 6.25
## BTBD7 9.65 12.00 13.09 16.05 13.99 7.61 13.91
## APBA3 10.98 12.55 18.51 14.45 11.79 11.12 16.16
## MKS1 11.09 7.98 8.26 12.36 8.02 9.89 10.98
## ABHD5 6.13 8.31 6.96 8.85 6.62 6.82 8.37
## KAL1 0.24 0.61 0.52 0.12 0.20 0.06 0.11
## AKAP8L 57.06 66.74 80.51 89.68 57.72 58.47 73.06
## MBTD1 4.29 5.45 6.67 5.26 5.98 3.45 5.45
## UTP18 46.32 48.60 46.85 57.75 54.57 42.63 58.61
## RNF216 8.17 8.22 10.87 17.02 7.55 12.01 9.16
## TTC19 34.05 39.09 32.20 29.66 37.71 23.54 36.56
## PTBP1 150.72 175.11 199.89 198.26 184.51 123.41 183.88
## DPF1 0.69 0.89 0.89 0.22 0.90 0.65 0.82
## SYT7 6.91 9.47 15.31 4.56 5.78 2.63 6.86
## LARS2 4.19 5.03 5.46 8.81 5.27 4.87 6.70
## PIK3C2A 6.90 10.62 12.10 11.12 9.02 5.65 7.60
## PLAUR 56.94 64.95 76.94 38.82 74.35 24.49 56.95
## ANLN 30.68 31.58 28.56 40.36 42.05 19.13 26.95
## WIZ 13.43 16.86 22.08 21.54 14.80 13.78 18.40
## RABGAP1 22.07 27.46 31.62 26.26 23.00 12.71 24.06
## DCN 0.00 0.00 0.00 0.00 0.00 0.00 0.39
## QPCTL 7.45 9.84 10.31 6.91 6.75 5.98 7.40
## PPP5C 50.62 46.69 47.20 60.66 46.12 41.61 53.83
## CEP68 3.15 2.84 2.97 3.42 4.14 3.03 3.72
## MAP4K3 7.48 8.76 9.11 12.29 8.96 7.38 7.79
## ZBTB32 0.22 0.05 0.03 0.00 0.45 0.00 0.09
## TYROBP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMEM159 45.18 55.35 60.48 27.52 47.61 19.92 43.52
## GABRA3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## BRCA1 8.99 8.87 10.35 16.31 11.52 7.09 9.95
## ERCC1 144.01 144.12 124.44 110.37 143.76 111.86 158.80
## CD22 0.60 1.27 1.72 1.60 0.99 1.15 1.67
## MBTPS2 5.61 6.37 6.53 3.99 6.34 2.81 4.93
## PRICKLE3 7.71 9.28 14.23 11.87 7.66 9.43 9.67
## LTF 0.20 0.09 0.01 0.00 0.25 0.00 0.00
## EXTL3 6.25 7.97 8.12 7.43 6.06 4.06 6.77
## NR1H4 0.00 0.02 0.00 0.02 0.01 0.13 0.26
## ELOVL5 50.31 64.55 59.85 49.08 61.45 41.34 47.74
## ALOX5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## KDM5D 0.00 0.00 0.02 0.00 0.00 0.00 0.04
## CALCOCO1 11.80 15.08 18.88 13.12 11.56 9.61 10.04
## UBR7 14.81 12.74 14.29 16.51 14.02 10.31 14.87
## MAP4K5 11.69 15.71 17.75 21.25 16.97 12.27 13.92
## EHD3 0.43 1.00 0.61 0.27 0.42 0.25 0.40
## PSMC4 119.09 114.76 124.08 109.98 115.54 80.36 125.48
## MAN2B2 2.64 3.03 3.55 2.24 3.31 1.66 3.66
## SLC7A14 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CLDN11 2.27 4.58 3.36 1.58 2.43 1.41 1.46
## SLC25A39 161.03 168.12 180.74 160.07 162.05 136.92 193.03
## MVP 39.61 28.31 38.60 65.33 34.11 30.71 43.14
## NUB1 29.44 32.03 39.78 25.18 28.42 16.42 28.76
## PGM3 23.93 45.58 51.30 21.67 30.03 11.97 22.15
## RWDD2A 3.20 6.31 7.14 7.22 4.13 3.33 3.81
## CLK1 58.29 61.56 69.24 68.27 63.09 76.20 65.33
## POLR3B 3.70 3.46 3.97 7.35 2.88 4.33 4.13
## ANGEL1 4.50 5.07 5.25 4.56 4.75 4.04 4.50
## RNF14 29.09 27.18 26.80 26.30 33.19 17.39 35.34
## DNASE1L1 27.51 34.77 37.30 16.50 26.46 15.48 23.01
## DDX11 20.25 21.44 21.99 53.18 16.72 33.57 26.63
## HEBP1 24.60 27.92 23.93 15.51 27.78 12.67 26.05
## GPRC5A 26.55 21.67 18.52 19.76 27.98 17.61 21.91
## MAMLD1 0.71 0.57 0.71 1.26 0.71 0.86 0.79
## CD6 0.02 0.00 0.00 0.00 0.02 0.48 0.04
## TACC3 25.64 25.94 24.87 38.72 24.64 23.95 27.17
## UFL1 12.22 15.58 17.33 9.14 16.05 6.78 9.91
## POLA2 17.81 14.72 18.21 26.37 16.57 17.85 19.05
## ZC3H3 7.75 8.84 11.60 12.03 7.78 6.83 10.75
## CAPN1 126.99 126.96 150.88 133.07 117.88 79.98 127.21
## ACPP 0.31 0.06 0.16 0.48 0.15 0.09 0.03
## MDH1 194.14 154.08 145.35 144.03 171.71 183.02 160.69
## SLC30A9 17.71 19.87 19.61 18.75 19.69 11.61 17.58
## MTMR11 2.29 2.75 2.63 5.94 1.95 3.04 1.63
## COX15 27.23 27.27 29.34 20.20 27.08 16.27 26.87
## CCDC88C 12.57 13.07 15.69 16.64 12.21 11.41 12.71
## YAF2 10.54 12.98 14.97 8.33 13.01 11.01 12.45
## ZMYND11 16.29 18.12 19.22 21.09 18.62 13.84 17.39
## WAS 0.18 0.02 0.26 0.27 0.16 0.00 0.42
## DPEP1 0.15 0.00 0.02 0.00 0.00 0.00 0.00
## BID 45.08 50.23 43.67 51.61 43.73 42.22 45.15
## MATR3 188.03 227.73 240.99 239.45 216.09 166.37 200.42
## NPC1L1 0.04 0.04 0.07 0.00 0.06 0.03 0.11
## XYLT2 10.68 11.05 10.25 15.47 10.24 9.67 12.87
## RGPD5 1.91 2.73 2.75 3.21 2.02 1.97 2.30
## STMN4 0.04 0.05 0.15 0.00 0.05 0.00 0.05
## NUDCD3 29.49 36.20 38.95 30.86 31.12 20.58 34.70
## ISL1 2.05 3.66 2.14 5.61 2.45 3.48 2.94
## CHDH 0.53 0.29 0.48 0.52 0.29 0.34 0.48
## IL20RA 0.89 0.70 0.98 0.60 0.40 0.70 0.26
## CLCA1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CLCA4 0.02 0.00 0.00 0.00 0.00 0.00 0.02
## GLT8D1 35.30 41.50 42.05 49.27 32.79 33.28 35.40
## ATP2C1 24.70 28.44 28.48 25.64 27.79 16.19 26.28
## SRCIN1 0.52 0.51 1.02 0.28 0.71 1.11 0.60
## IGF1 0.00 0.00 0.00 0.00 0.00 0.60 0.15
## SLC38A5 64.59 99.69 94.28 67.29 69.80 57.67 77.06
## MAGIX 1.59 0.89 1.34 1.07 1.30 0.80 1.81
## RALBP1 23.25 29.05 33.43 23.35 25.74 14.21 22.11
## RUFY3 10.79 12.94 14.18 15.32 10.13 13.15 12.85
## CNTN1 0.31 0.23 0.47 0.17 0.37 0.43 0.16
## SLC11A1 0.13 0.21 0.32 0.07 0.11 0.81 0.19
## WWTR1 22.89 26.86 26.73 21.56 25.77 15.54 23.98
## AGPS 7.98 9.44 8.15 9.67 8.89 5.22 8.31
## CXorf56 15.90 22.29 21.78 17.28 20.69 11.41 20.99
## ATP1A2 0.00 0.00 0.00 0.00 0.00 0.04 0.01
## TTC27 12.92 16.02 13.83 18.82 14.99 9.51 15.73
## ZNF582 0.19 0.18 0.34 0.00 0.18 0.28 0.10
## VSIG2 0.00 0.06 0.00 0.00 0.00 0.00 0.00
## PHLDB1 8.09 10.64 7.67 17.86 11.27 14.35 12.16
## MARCO 3.79 4.69 6.64 1.78 2.78 2.25 2.95
## CYP24A1 0.91 0.85 0.81 0.09 0.39 0.15 0.13
## PRDM11 0.93 0.86 1.32 1.64 1.03 1.05 0.92
## SYT13 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## SNAI2 51.20 73.83 82.68 59.10 67.47 56.81 52.22
## CD74 6.83 7.02 7.96 4.46 9.67 5.21 8.54
## HGF 0.05 0.00 0.02 0.00 0.04 0.00 0.10
## ZRANB1 12.90 16.59 17.40 18.01 13.77 9.32 13.27
## NCDN 8.70 8.52 9.79 9.23 7.78 6.20 9.47
## GPR124 0.01 0.07 0.04 0.00 0.05 0.02 0.15
## ZFP64 21.28 28.98 34.32 19.28 22.75 14.36 25.95
## MNAT1 51.49 51.01 51.99 43.53 45.66 52.67 46.35
## SAMD4A 5.28 6.09 4.85 5.94 6.62 5.99 7.90
## RUNX3 0.04 0.15 0.09 0.00 0.05 0.01 0.05
## MRE11A 10.18 10.00 12.46 11.02 9.26 8.78 8.41
## PLEKHB1 0.06 0.02 0.25 0.00 0.03 0.08 0.19
## SERPINB1 107.57 130.85 204.51 30.40 64.48 39.58 42.74
## CYP3A43 0.03 0.03 0.07 0.00 0.00 0.00 0.23
## SLC7A9 0.05 0.13 0.12 0.00 0.23 0.00 0.13
## SPAST 4.94 4.81 5.39 5.80 7.00 2.69 5.87
## NRXN3 0.00 0.00 0.00 0.00 0.01 0.06 0.00
## OSBPL5 30.31 39.16 42.91 17.73 27.67 12.65 22.79
## AQR 28.20 29.06 32.74 37.62 31.21 21.90 32.17
## CPS1 1.12 1.17 1.60 1.00 1.03 0.75 2.96
## C8B 0.00 0.00 0.00 0.00 0.00 0.00 0.14
## FHL1 15.19 19.50 21.36 15.63 15.55 11.44 11.83
## RTFDC1 140.13 152.47 150.25 133.90 157.48 101.88 154.26
## GABRA1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NLRP2 14.11 12.67 12.63 21.75 13.77 11.63 16.42
## SLC45A4 2.67 2.35 3.76 4.35 3.04 1.36 3.81
## RNF10 81.78 86.56 107.56 92.27 88.52 54.98 85.12
## ZNF839 7.98 7.26 7.14 13.44 7.60 7.84 8.75
## ZDHHC6 36.20 37.74 40.52 31.56 41.88 36.12 46.15
## GRAMD1B 0.06 0.04 0.00 0.03 0.05 0.04 0.05
## RNH1 143.71 167.35 188.01 167.69 140.61 98.45 181.61
## NDUFS1 53.45 66.88 63.41 47.08 57.02 32.34 52.81
## RB1CC1 15.50 21.04 23.53 13.03 15.39 6.37 13.90
## ERP44 54.33 66.21 73.42 32.25 56.07 27.47 44.32
## ALAS1 26.27 33.34 37.04 22.29 25.35 16.86 29.07
## BIRC3 17.83 23.21 37.06 13.37 17.68 8.44 10.99
## AKAP11 5.11 6.32 7.14 6.61 7.45 3.57 5.73
## GLRX2 55.56 41.27 36.96 56.41 54.77 63.27 58.29
## SNAPC1 18.09 22.69 18.77 17.47 23.75 14.02 18.90
## DERA 16.64 12.66 16.37 12.11 19.34 13.04 18.96
## STRAP 165.99 181.60 166.67 154.96 194.37 148.18 174.69
## ABCC2 0.47 0.55 0.57 0.88 0.51 0.54 1.52
## DEF6 25.57 20.72 25.96 22.85 18.66 13.96 17.68
## PLEKHO1 2.10 2.35 2.24 1.92 1.77 0.80 1.66
## GCLM 26.36 15.68 21.97 52.12 49.31 26.95 58.14
## UBR2 5.82 6.00 7.48 8.37 6.12 4.97 6.94
## EHD2 42.66 51.27 62.19 32.18 43.49 22.30 45.56
## DEPDC1 8.02 10.20 10.95 7.43 10.15 6.23 6.55
## CCDC28A 12.24 12.27 12.38 8.63 10.51 6.14 10.47
## RRAGD 1.80 2.79 2.52 1.21 3.43 0.40 2.76
## HSF2 10.00 11.76 12.42 12.17 11.30 7.88 10.64
## PHF20 13.86 19.17 18.97 19.80 17.90 11.93 17.11
## HSD17B6 1.55 1.20 1.30 0.92 1.34 2.21 1.02
## NR1H3 11.44 7.36 8.88 7.86 7.84 7.64 9.48
## TYMP 119.11 84.04 139.05 69.43 103.12 49.61 100.18
## NCAPH2 23.72 23.92 27.28 48.35 26.55 25.77 30.81
## TOMM34 73.23 80.33 74.99 80.09 97.49 61.52 108.02
## SEC63 74.46 114.42 115.56 54.62 88.90 37.42 68.36
## KPNA6 13.90 17.87 19.48 9.26 15.91 7.66 13.82
## VIM 196.25 287.35 304.63 194.15 246.45 150.31 226.48
## RTEL1-TNFRSF6B 3.53 5.55 5.24 5.27 3.64 3.73 4.39
## FAS 22.17 26.70 26.49 20.00 30.23 15.13 22.83
## RNASET2 5.38 3.93 4.16 6.59 5.27 7.49 6.26
## CD44 410.28 441.00 457.72 269.55 458.04 238.32 352.62
## KCNG1 8.23 13.44 15.24 5.98 8.57 3.95 12.76
## AGPAT4 8.77 11.13 11.81 4.66 10.35 6.64 8.10
## SLAMF7 0.03 0.11 0.03 0.00 0.15 0.00 0.20
## BTN3A1 4.81 5.22 6.91 2.37 4.03 1.72 2.59
## MIPEP 15.78 12.09 11.62 19.51 12.17 15.41 10.49
## PRKCH 5.27 6.25 6.81 7.41 5.29 4.55 4.48
## INSRR 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## IFNGR1 52.48 54.65 59.40 42.10 45.34 34.94 40.70
## B4GALT7 22.23 26.43 28.41 20.59 24.46 17.11 27.90
## SH2D2A 6.93 8.97 8.47 2.20 7.51 3.89 5.23
## VRK2 25.98 26.06 29.01 20.54 25.46 17.06 22.94
## TNFRSF1B 0.89 1.22 1.15 0.19 0.90 0.40 0.69
## VEZT 34.76 39.26 35.52 43.61 45.39 26.09 34.23
## POU2F2 0.54 1.99 1.03 1.19 1.43 1.71 3.01
## BRD9 38.31 47.29 46.11 61.42 47.64 47.07 55.92
## SNX1 33.80 34.92 39.57 44.24 29.90 31.83 30.08
## TBPL1 24.69 26.52 25.00 24.53 23.31 24.61 24.09
## ARNTL2 13.20 15.63 15.65 6.50 14.16 6.97 11.24
## BCLAF1 36.91 35.62 38.63 62.31 37.62 27.43 32.32
## SLC39A9 27.97 34.33 39.05 23.95 32.49 14.74 29.10
## ANK1 0.15 0.02 0.06 0.00 0.24 0.29 0.04
## IBSP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TFB1M 16.52 16.80 13.58 12.91 14.03 14.88 14.10
## RABEP1 21.33 26.50 24.51 22.98 26.84 22.65 22.53
## HMGB3 47.67 42.94 37.00 44.87 43.98 26.92 38.32
## NUP160 17.09 20.15 20.57 29.84 18.97 15.90 17.81
## BAK1 75.57 76.47 74.95 69.12 76.08 49.02 95.79
## MUSK 0.00 0.00 0.00 0.00 0.02 0.00 0.00
## IKZF2 0.61 0.28 0.58 0.31 0.38 0.64 0.45
## GRN 113.73 98.92 111.19 149.96 123.58 87.84 145.29
## FAM13B 5.63 7.14 8.29 12.47 7.43 5.51 9.13
## ARHGAP31 0.11 0.12 0.09 0.00 0.17 0.08 0.19
## CENPQ 10.24 12.49 13.32 12.51 12.05 7.16 9.51
## SARS 240.04 297.84 316.83 175.58 230.39 140.02 267.31
## RANBP3 28.03 38.07 39.21 49.68 28.91 22.75 31.85
## ARID4A 3.02 2.79 4.18 6.78 2.73 2.44 2.53
## TSSC1 29.95 31.28 33.46 30.96 29.89 20.57 32.81
## PNPLA6 32.27 28.65 29.17 30.61 29.29 17.41 36.01
## IFT88 4.39 4.15 3.17 2.86 5.66 3.93 4.46
## ALG1 20.23 21.89 23.53 23.87 19.19 18.67 23.51
## ZCCHC8 21.53 22.05 24.48 38.00 25.16 29.26 29.57
## ABCF2 26.87 34.54 37.15 42.35 28.24 23.39 34.70
## CHPF2 14.98 18.97 20.73 21.53 15.04 14.39 17.98
## LRRC7 0.06 0.02 0.06 0.06 0.08 0.03 0.07
## FUT8 1.81 1.64 0.96 3.33 1.14 1.15 1.35
## UBA6 9.79 10.79 11.02 14.42 13.21 10.68 10.05
## GAB2 0.28 0.56 0.77 0.07 0.29 0.24 0.35
## ATP6V0A1 13.51 13.72 14.17 19.65 19.58 13.72 23.90
## PIAS1 14.77 16.25 20.11 10.92 13.79 10.41 13.30
## SLC4A7 5.98 8.48 9.08 10.27 8.85 5.54 7.07
## APBA2 2.44 2.21 2.57 3.76 2.62 2.55 3.33
## MAP2K3 38.32 57.16 48.62 44.24 60.49 31.22 53.63
## EFCAB1 1.12 1.20 0.92 0.72 0.97 0.37 0.80
## TMSB10 5413.30 4744.12 3855.37 5567.62 4587.78 7591.85 4709.88
## ASTE1 3.90 3.57 4.37 3.62 3.93 3.37 4.79
## RNF19A 8.77 10.84 11.25 21.34 12.19 8.82 12.45
## PEX3 29.20 27.01 25.88 37.76 32.06 36.84 32.14
## GABARAPL2 85.22 79.46 80.05 47.70 82.87 68.12 75.28
## MYOC 0.02 0.00 0.00 0.00 0.00 0.00 0.00
## SH3YL1 53.43 69.68 70.24 37.76 59.25 35.47 43.47
## FAM136A 40.71 43.82 38.65 45.34 40.77 43.71 42.26
## VCL 25.33 24.41 25.46 37.19 33.98 23.45 32.22
## DEPDC1B 12.86 14.26 12.81 11.52 13.79 11.49 11.29
## DAPK2 11.12 7.91 13.21 7.72 7.21 5.09 8.15
## NSMAF 17.53 25.85 26.12 19.18 17.66 13.16 20.68
## ADSS 37.08 47.88 47.40 31.78 43.70 29.60 33.41
## STAP1 0.00 0.02 0.02 0.00 0.09 0.00 0.00
## TIMP2 35.73 43.67 46.67 30.60 49.59 15.24 45.14
## RFC1 30.30 37.88 42.07 42.29 34.70 29.87 31.07
## TBC1D23 17.23 19.44 20.66 15.64 21.57 13.70 17.61
## CUL3 58.64 61.42 68.04 63.48 64.31 61.73 65.66
## MYOM2 1.66 1.01 1.51 2.13 1.95 1.61 2.22
## OTC 0.00 0.00 0.00 0.00 0.00 0.00 0.68
## CYP46A1 0.00 0.00 0.00 0.00 0.00 0.07 0.00
## ZZZ3 20.21 24.75 25.56 31.57 23.44 17.92 25.15
## SLC18A1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## USP2 0.42 0.49 0.79 0.28 0.62 0.23 0.54
## CASR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TUBG2 11.85 10.05 12.47 11.27 7.44 10.77 7.34
## RPL26L1 140.62 110.39 104.60 127.21 132.00 170.43 139.25
## FLT4 0.03 0.00 0.00 0.00 0.00 0.00 0.00
## NSUN2 62.35 75.24 78.88 102.51 76.44 77.15 80.84
## FBXO42 9.24 14.67 15.68 16.68 10.46 8.29 11.94
## MFAP3 20.58 24.34 28.11 20.71 25.48 13.06 22.42
## MRI1 15.95 16.57 21.70 25.43 13.97 15.37 16.69
## METTL1 37.80 41.93 40.15 42.18 36.22 39.60 37.71
## HOXC8 1.30 1.55 1.08 1.65 1.28 0.98 0.85
## AGA 6.09 5.58 5.67 4.76 7.92 3.48 7.12
## PI4K2B 12.89 13.94 14.64 13.27 14.93 9.38 11.65
## BOD1L1 10.17 13.69 15.51 19.24 12.74 9.48 11.86
## MAT2B 63.29 62.04 62.88 52.79 65.33 39.03 53.38
## TLL1 0.55 0.93 0.62 0.93 0.89 0.92 0.71
## EDC4 32.51 25.31 32.39 56.74 28.69 30.09 39.61
## TRIO 14.61 18.12 18.67 28.61 17.99 15.85 17.98
## VCAN 4.47 5.19 6.88 4.01 6.19 2.96 4.87
## CLEC16A 4.81 4.16 6.34 6.78 4.94 5.08 5.81
## MSR1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CDH1 111.93 125.85 169.08 82.64 118.37 47.92 82.37
## SKIV2L2 64.11 71.59 63.08 56.34 67.01 45.01 59.70
## DNAH5 0.54 0.39 0.42 1.15 0.55 0.57 0.40
## ZFYVE16 7.11 7.59 9.12 13.29 8.57 7.40 7.71
## FAM65A 21.90 34.42 33.93 30.97 33.45 23.47 34.48
## C6 0.00 0.00 0.00 0.00 0.00 0.00 0.90
## RAI14 9.41 15.33 12.07 17.16 10.16 9.40 12.38
## SOX30 0.04 0.04 0.24 0.00 0.03 0.00 0.11
## PNKP 20.46 28.18 29.70 44.36 25.13 24.13 30.11
## BEST2 0.02 0.00 0.06 0.00 0.05 0.00 0.05
## PHLPP2 1.45 1.58 1.75 3.05 2.10 2.14 2.68
## SPDL1 15.86 18.92 17.45 21.19 18.07 21.68 19.18
## STAU2 6.94 7.70 8.71 8.80 5.25 3.84 4.91
## PQLC2 11.69 12.23 17.03 17.86 11.96 9.90 21.93
## CTNS 9.04 10.15 12.66 9.51 10.27 5.76 16.09
## RTN4R 6.19 8.04 8.90 9.62 7.13 6.19 10.01
## PHF23 28.95 30.72 32.12 37.72 33.26 21.53 39.12
## CDH10 0.00 0.00 0.00 0.00 0.03 0.00 0.00
## INPP4A 3.10 3.46 3.89 2.93 2.89 2.39 2.93
## RAB27B 2.02 1.92 3.15 1.15 1.34 0.40 1.05
## PSMA4 227.33 216.67 207.10 198.40 215.12 201.97 202.13
## MYO16 0.04 0.04 0.10 0.00 0.07 0.06 0.07
## LSG1 22.06 25.02 29.82 30.46 24.61 21.55 26.78
## PARP3 10.05 7.94 9.90 9.82 6.80 7.61 7.49
## TNC 64.93 89.06 101.11 42.81 65.03 35.55 62.10
## THAP3 21.87 20.16 24.03 16.47 19.96 14.11 23.06
## FAM65C 0.07 0.01 0.17 0.44 0.16 0.07 0.12
## TDP1 8.73 11.02 9.03 8.21 7.97 6.84 7.72
## AIFM2 40.26 47.85 55.46 43.18 50.14 24.55 64.23
## C2orf83 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SPATA7 3.36 3.67 2.83 3.32 3.84 2.57 3.50
## MED17 29.87 34.53 35.21 58.57 38.14 30.50 39.04
## RETSAT 41.82 45.82 71.35 35.36 37.85 25.51 41.26
## CAPG 310.53 251.67 301.81 209.10 242.81 177.20 262.21
## AP2S1 262.93 203.12 189.87 258.66 249.42 255.39 312.68
## USH2A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZPBP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TG 0.25 0.56 0.55 1.31 1.09 0.52 0.14
## ADAM28 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## BARX2 25.88 29.26 36.43 8.24 16.18 10.20 8.63
## DCUN1D1 12.99 13.71 14.54 20.04 14.33 6.77 12.59
## JADE2 8.79 7.13 9.21 9.70 5.78 6.01 6.22
## ZIC2 0.10 0.26 0.21 0.50 0.19 0.10 0.11
## LCP2 0.01 0.00 0.00 0.00 0.00 0.00 0.00
## TRIT1 26.06 24.91 25.91 30.54 24.03 18.56 25.52
## ADRB1 0.56 1.10 0.86 0.21 0.30 0.11 0.24
## GUCA2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CUL7 3.81 4.56 6.19 5.49 2.80 2.79 3.95
## CTNNA1 167.53 195.12 230.19 268.93 174.45 153.67 215.37
## PHKA2 9.40 9.07 10.32 15.11 9.93 12.91 11.39
## CNTLN 2.74 2.47 3.09 1.71 2.95 1.55 2.38
## EPHA3 0.00 0.01 0.01 0.00 0.01 0.00 0.03
## HSPA5 1278.34 2785.77 3115.57 571.14 1410.75 503.00 913.28
## DSG2 34.28 41.38 48.47 41.33 37.28 21.97 32.40
## GEMIN8 7.50 7.91 8.53 7.52 8.31 6.60 11.11
## OFD1 24.23 21.90 25.92 33.03 27.19 24.67 26.33
## GPM6B 0.97 0.81 0.64 0.19 0.49 0.53 0.40
## MAGEC2 0.00 0.00 0.00 0.21 0.00 0.00 0.00
## PREX2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## WDR37 6.17 7.24 7.60 13.25 7.90 7.70 8.88
## YTHDC2 8.55 8.85 9.17 13.55 10.63 8.76 10.40
## CTPS2 5.48 4.44 4.84 3.26 7.07 5.93 3.58
## ATP6V1H 43.26 48.89 57.74 38.77 57.83 30.34 55.37
## POLR2B 40.83 46.07 49.24 73.46 47.30 47.03 49.56
## FAM214A 9.23 10.42 10.53 8.78 11.01 7.71 9.88
## ARAP2 2.06 2.75 2.69 6.24 2.45 2.42 2.95
## TPR 34.35 40.10 37.93 57.72 29.33 37.51 34.40
## CP 0.00 0.00 0.03 0.00 0.15 0.00 1.69
## KIAA0556 3.40 2.51 3.34 5.01 3.39 4.92 4.06
## DTNBP1 14.90 13.74 12.28 22.93 14.60 9.37 15.94
## XK 0.16 0.17 0.14 0.19 0.13 0.04 0.05
## ANO2 0.00 0.12 0.00 0.00 0.00 0.00 0.02
## C12orf4 9.80 10.71 10.33 9.05 11.23 5.00 11.39
## SCML1 9.91 14.05 13.40 15.98 14.44 9.14 10.77
## WWC3 2.49 3.72 3.08 2.29 2.98 3.21 2.79
## ARHGAP6 0.01 0.02 0.00 0.00 0.01 0.01 0.00
## FAM184B 0.49 0.63 0.74 0.60 0.60 0.65 0.58
## MAP4 43.72 57.11 69.10 63.05 51.17 40.70 55.22
## GOPC 13.16 18.92 21.91 12.66 14.46 9.53 11.16
## ROS1 0.03 0.12 0.15 0.00 0.03 0.04 0.02
## USP28 6.15 6.41 7.85 7.58 5.53 4.01 5.30
## HDAC9 3.61 4.55 4.70 6.30 6.75 3.55 9.38
## TSPAN17 22.15 24.48 25.52 42.04 24.84 26.19 34.28
## NOP16 139.47 147.06 136.31 173.86 136.03 152.23 152.76
## CC2D2A 6.85 6.61 6.37 5.77 7.30 4.13 6.29
## RRM2B 14.39 24.82 27.75 8.30 23.58 3.26 14.14
## ZNF800 8.86 9.38 12.90 12.69 11.05 8.12 10.61
## TNFRSF17 0.00 0.00 0.00 0.00 0.00 0.00 0.06
## SNX29 3.59 2.92 4.05 1.54 3.11 1.36 2.99
## LMO3 0.08 0.05 0.18 0.04 0.16 0.19 0.06
## MRPS10 87.62 89.47 87.47 62.02 92.08 59.82 84.17
## GUCA1A 0.00 0.00 0.05 0.00 0.00 0.00 0.00
## RSF1 7.27 9.98 10.34 11.72 7.07 6.71 6.78
## VPS13D 14.97 16.51 17.26 18.85 16.87 10.03 14.85
## CELF2 1.31 2.30 1.94 2.16 2.39 0.80 2.42
## FAM120A 67.36 90.79 97.39 78.82 84.72 51.61 74.11
## R3HDM1 8.51 12.47 12.39 10.50 10.47 7.74 9.20
## COL9A2 0.27 0.25 0.11 0.12 0.18 0.18 0.12
## KITLG 2.15 3.49 3.94 3.51 4.81 1.56 4.48
## ERCC8 17.72 15.95 18.61 17.46 15.54 12.46 14.51
## ADAMTS6 0.21 0.17 0.08 0.29 0.15 0.30 0.20
## H6PD 3.63 5.23 5.99 2.80 4.21 1.73 3.78
## VAMP3 75.88 86.44 94.09 53.27 87.37 42.70 76.65
## PER3 11.16 14.68 19.09 8.13 13.82 7.08 13.30
## UTS2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TNFRSF9 0.03 0.02 0.17 0.00 0.00 0.00 0.03
## EPN3 10.26 6.59 10.39 5.86 6.63 4.97 5.65
## LTBP1 2.13 2.71 3.57 1.78 1.94 1.49 1.94
## RCN1 79.19 84.60 87.48 77.13 79.84 73.65 67.10
## ELN 0.40 0.54 0.38 0.92 0.13 0.49 0.16
## RFC2 44.86 42.21 46.27 39.79 48.47 36.10 57.23
## ARID1B 4.44 5.38 6.44 4.14 4.23 3.90 4.23
## CLPTM1L 75.12 93.97 109.13 86.10 90.14 58.88 86.08
## NEDD4L 12.64 21.40 17.95 25.87 20.66 19.28 24.21
## FOXP3 0.13 0.07 0.05 0.00 0.10 0.15 0.07
## PPP1R3F 1.18 1.17 1.94 2.55 0.83 0.72 1.22
## HEXB 210.56 223.98 208.18 241.01 255.19 151.21 268.73
## PTCD2 12.15 12.25 11.56 9.98 12.20 7.82 11.57
## KIAA2022 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## JKAMP 37.53 38.53 40.08 47.76 44.14 36.94 42.20
## DKK3 33.84 82.24 43.20 50.12 51.02 38.78 46.43
## ARHGEF5 12.47 16.82 20.91 13.32 15.87 10.13 16.24
## NFE2L3 3.09 2.86 3.16 4.40 3.04 4.13 2.84
## MCUR1 39.16 42.32 40.36 29.63 42.17 29.51 38.12
## LIMA1 110.43 167.85 121.23 150.22 160.53 106.31 125.48
## LETMD1 62.07 74.38 80.08 43.27 58.45 36.76 53.89
## SLC4A8 0.14 0.14 0.23 0.31 0.50 0.17 0.12
## LAMC3 2.68 3.14 3.11 0.51 2.02 1.57 2.35
## PTGER3 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## TNIP3 0.03 0.09 0.50 0.00 0.21 0.00 0.06
## MAPK9 28.20 29.59 32.06 26.83 26.97 17.69 24.23
## COL23A1 0.15 0.23 0.10 0.00 0.25 0.05 0.08
## BCAR1 27.46 30.93 33.11 53.82 32.18 30.59 44.68
## FAM160A2 11.48 14.37 16.60 14.46 14.85 15.40 18.28
## HERPUD1 97.40 236.10 279.86 46.87 120.38 35.46 76.53
## HOMER3 95.10 92.39 87.11 107.10 106.22 71.13 110.53
## RAD51 20.91 19.03 20.29 24.21 21.41 14.45 20.67
## POLQ 2.33 1.98 1.93 2.97 1.80 3.15 2.01
## PIK3CB 9.80 10.41 12.28 7.66 10.57 4.30 8.27
## CYBA 60.08 49.42 54.34 56.82 51.00 47.98 63.50
## THOC3 157.69 161.76 148.45 151.89 180.35 98.00 139.74
## HEBP2 140.84 115.48 130.21 98.49 120.01 86.00 114.08
## MPHOSPH9 9.56 8.32 9.88 11.96 8.35 11.81 9.01
## PLEKHA5 4.34 3.82 4.74 6.24 4.43 3.54 3.96
## PRSS8 63.38 66.48 75.78 52.35 76.82 29.28 78.63
## SIKE1 55.20 53.24 46.41 38.30 58.89 47.68 46.43
## RRP12 37.61 42.61 44.32 56.30 44.31 42.46 50.72
## FNIP2 1.85 1.40 1.64 2.85 1.89 1.80 2.85
## MSMO1 100.84 203.55 163.45 87.76 125.62 90.32 99.20
## TTC17 32.43 39.81 48.34 30.12 32.02 27.25 34.61
## ALX4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## FSTL4 0.62 0.35 0.87 0.33 0.37 0.42 0.47
## FOXN3 2.62 3.50 4.76 3.38 3.46 0.86 2.20
## METTL24 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## AKR7A2 31.24 27.25 26.36 22.14 24.70 25.19 28.07
## MRTO4 69.99 72.42 68.09 58.37 72.59 62.11 79.81
## NNAT 1.16 1.10 1.55 2.15 1.29 1.87 1.27
## USE1 37.40 36.67 35.59 48.53 34.96 29.07 38.35
## MCF2L2 1.26 0.50 1.08 1.35 0.73 1.05 0.83
## NRIP2 0.25 0.35 0.49 0.62 0.36 0.55 0.30
## LAMA3 81.57 76.23 72.33 113.74 91.58 84.20 89.29
## AP5M1 12.58 10.19 12.23 10.57 11.00 13.15 13.02
## ANAPC4 13.59 14.88 11.43 19.35 14.87 18.27 15.43
## KCNQ1 0.05 0.13 0.14 0.00 0.02 0.00 0.12
## TRAPPC3 94.97 101.49 96.00 94.60 97.34 72.94 101.42
## THRAP3 30.35 30.43 36.18 49.17 32.39 30.87 36.81
## PHPT1 230.86 217.38 232.10 190.18 211.19 171.34 230.32
## ENTPD2 35.13 38.57 56.73 30.32 40.81 25.04 42.07
## LY75 0.47 0.61 0.29 0.08 0.32 0.21 0.22
## ARID4B 5.20 6.94 6.91 8.29 6.70 3.70 6.59
## OPN3 4.04 4.63 4.88 2.29 3.13 1.19 2.30
## SDCCAG8 40.80 35.91 32.54 61.18 33.09 79.57 38.80
## PTPRN 0.10 0.07 0.12 0.00 0.03 0.00 0.16
## HHAT 0.46 0.48 0.43 0.19 0.34 0.39 0.54
## KIF1B 7.39 8.23 8.72 8.57 8.74 4.06 7.99
## FOXC1 5.48 5.87 6.97 4.95 6.06 2.79 4.76
## TBC1D22A 7.88 9.10 11.20 7.43 8.25 5.28 9.48
## SYNE2 18.89 18.68 21.27 25.68 18.50 14.64 16.91
## PLEKHH1 1.88 1.33 1.44 1.20 2.01 2.05 1.84
## ATP9A 3.27 5.14 6.33 2.83 2.77 1.64 3.65
## SPO11 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CBLN4 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## CHRDL2 0.03 0.03 0.00 0.00 0.00 0.00 0.15
## FAM168A 4.68 5.06 6.03 3.13 4.27 2.05 4.25
## RELT 7.33 8.60 8.55 17.90 9.66 10.45 10.77
## GALC 0.89 0.81 0.59 0.23 0.60 0.78 0.69
## NOP58 111.12 129.59 126.10 141.02 150.23 100.14 144.28
## SZRD1 59.78 64.65 70.84 65.32 62.21 38.84 71.37
## KCNH2 0.03 0.03 0.00 0.00 0.00 0.00 0.01
## CUL1 20.20 18.02 23.68 34.40 18.39 20.55 20.44
## FAM114A2 13.36 13.64 15.28 20.50 17.03 9.67 16.26
## CYFIP2 0.79 0.42 0.90 1.68 0.57 0.02 0.67
## TAB2 23.17 29.95 31.97 21.11 25.79 14.25 21.06
## GINM1 33.05 39.21 37.17 24.29 37.72 21.27 34.09
## EIF2AK2 11.31 11.64 13.24 13.41 14.17 5.26 9.34
## USP36 45.10 61.11 73.17 65.58 61.71 42.26 72.81
## KMT2C 6.71 8.19 9.99 7.84 8.39 5.07 6.44
## MCOLN3 2.52 2.63 2.87 6.65 3.25 5.65 4.45
## CCDC85A 0.01 0.01 0.04 0.00 0.00 0.00 0.01
## PUM2 29.26 36.92 42.45 32.49 35.63 19.26 31.00
## MRPL43 105.07 92.81 92.87 78.85 97.33 81.12 103.67
## ITIH4 0.66 0.76 0.69 0.15 0.62 0.43 2.91
## ITIH1 0.00 0.00 0.00 0.00 0.00 0.00 1.60
## C4orf27 34.09 28.90 23.75 32.50 35.06 25.98 27.84
## ZFR 32.70 35.97 38.37 45.17 39.89 29.70 34.92
## ZNF280C 1.12 1.26 1.33 1.15 2.00 0.71 1.60
## NPFFR2 0.00 0.03 0.00 0.00 0.00 0.09 0.10
## PHF21B 0.01 0.00 0.01 0.00 0.00 0.00 0.07
## TRAF1 1.98 1.82 2.04 3.69 2.09 2.84 2.03
## RC3H2 24.06 26.67 27.28 26.48 43.21 21.42 23.20
## PCGF2 22.23 25.36 27.78 13.76 20.52 11.41 19.73
## IL17RB 1.04 0.54 0.81 0.61 0.77 0.70 0.74
## TRAF3IP2 60.53 77.82 78.15 46.28 66.19 36.79 60.10
## GYG2 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## DCBLD2 10.15 17.09 13.83 17.13 15.96 14.42 18.23
## SERPINB3 20.69 28.27 29.28 13.28 13.74 11.66 6.74
## SOAT1 8.56 10.12 8.44 10.00 9.71 4.54 9.80
## PKP2 19.40 22.13 22.79 19.32 21.22 13.47 21.38
## MSH4 0.06 0.07 0.09 0.16 0.08 0.06 0.05
## F7 0.00 0.00 0.00 0.00 0.00 0.00 0.18
## GDI2 167.33 167.56 167.13 138.83 162.15 109.50 152.57
## PRDM1 1.98 2.68 4.37 1.14 2.85 0.73 1.01
## ATG5 20.32 23.62 24.40 14.29 24.09 15.36 21.61
## TMCC3 2.53 2.02 2.56 0.98 2.45 0.88 1.38
## PITHD1 69.75 78.91 73.20 65.50 86.72 50.01 83.06
## MTA3 19.87 21.07 19.82 11.08 18.13 14.21 15.74
## USP13 0.75 0.62 0.71 0.98 0.68 0.49 0.67
## ATP11B 13.18 16.41 17.07 13.41 15.78 6.71 11.57
## LAMC2 131.89 215.71 141.93 110.78 189.21 125.85 147.76
## CDK14 2.19 2.97 3.26 1.49 2.57 1.40 1.55
## SEC61A1 80.20 129.30 161.82 83.98 90.35 53.56 102.78
## PPP1R12A 11.90 13.90 13.82 17.13 16.57 11.19 14.89
## RASGRF1 0.34 0.22 0.21 0.12 0.29 0.34 0.48
## CAMK2B 4.79 3.97 5.70 6.36 3.62 3.61 3.58
## CROCC 7.72 7.19 10.48 22.02 7.68 12.01 12.98
## POLR3E 33.98 36.35 38.83 34.64 33.10 31.07 30.82
## ATP2B4 50.49 63.72 75.88 19.32 46.54 18.37 31.54
## ZC3H11A 70.46 88.51 96.98 113.25 84.44 61.27 77.72
## RIOK2 45.11 45.04 43.48 61.98 42.91 44.94 49.17
## YIPF1 17.40 18.39 19.34 19.12 19.66 11.90 22.50
## NDC1 18.19 21.25 22.59 19.25 18.11 13.93 16.29
## DGKG 0.02 0.02 0.11 0.01 0.06 0.00 0.01
## FLYWCH1 17.04 22.81 27.94 31.53 15.69 14.88 25.03
## UNKL 11.21 9.61 12.59 14.02 12.86 10.61 14.65
## TBXAS1 2.91 1.63 2.38 3.76 1.21 1.78 1.59
## PARP12 15.16 16.68 21.42 22.54 16.38 16.97 18.64
## ALDH18A1 34.62 39.44 41.67 34.76 33.82 23.93 32.37
## TARBP1 18.41 16.86 14.58 33.49 20.50 35.68 24.15
## PET112 17.57 15.16 16.14 16.41 15.15 13.60 19.08
## MXD1 22.64 32.45 35.71 18.53 26.92 12.39 33.79
## CDK17 8.41 11.19 11.06 12.04 11.86 7.88 11.05
## DNAJC25 45.94 55.50 57.89 60.06 59.81 55.06 34.01
## SLC2A3 3.60 5.74 5.72 7.80 4.76 4.93 3.86
## PSD 0.68 0.79 0.88 1.02 0.81 0.07 0.73
## CTDP1 8.76 10.28 11.93 13.92 8.97 9.19 11.52
## YBX3 270.42 330.42 325.57 218.42 283.90 184.86 242.91
## STYK1 0.77 1.04 1.89 1.84 1.43 0.75 1.59
## WNK1 10.51 14.84 19.20 15.77 13.40 10.31 14.54
## CCAR1 61.13 65.20 62.26 81.43 65.06 53.12 61.89
## OGFR 45.12 48.21 54.44 58.94 41.78 38.72 47.31
## GNA15 55.70 67.21 74.35 31.56 52.50 24.38 48.45
## CREB3L3 0.00 0.00 0.00 0.00 0.01 0.00 0.05
## PIGV 8.29 7.46 8.96 5.04 7.77 5.24 8.08
## PTPRU 16.10 17.72 19.07 18.09 15.02 9.72 15.24
## SNRNP40 64.27 58.07 58.20 66.82 72.08 61.05 80.12
## RIMBP2 0.01 0.00 0.00 0.00 0.00 0.00 0.02
## COL11A1 0.00 0.04 0.00 0.00 0.00 0.00 0.04
## QSER1 6.22 6.28 8.10 9.19 7.18 5.05 6.92
## MPC1 33.68 25.22 27.22 33.67 29.76 34.39 29.53
## ACAA1 19.85 15.19 17.95 36.51 17.97 25.10 22.83
## BCAT1 0.04 0.04 0.08 0.32 0.09 0.00 0.16
## HDAC7 26.87 32.86 27.66 48.54 30.06 36.41 31.90
## LZTS1 0.06 0.00 0.00 0.00 0.01 0.00 0.01
## PRDM6 0.05 0.10 0.30 0.00 0.16 0.03 0.08
## WNT8A 0.05 0.00 0.00 0.00 0.00 0.00 0.00
## SPAG4 3.15 3.04 2.58 5.45 1.90 4.27 2.97
## NCKAP1 52.65 68.62 74.39 76.91 63.17 43.54 57.12
## MRPS35 57.40 57.94 49.78 47.53 54.96 40.79 47.06
## GUCY1B3 0.02 0.02 0.04 0.00 0.00 0.00 0.02
## SFSWAP 23.64 26.38 31.28 31.46 23.65 21.02 25.11
## TNK2 29.13 24.40 34.45 48.41 25.75 36.56 37.54
## MON2 7.20 8.66 8.40 7.57 7.59 4.75 6.21
## CDH3 120.44 99.87 114.22 112.02 100.40 57.94 95.51
## ARSF 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GPBP1 71.20 74.89 78.93 80.77 78.99 52.02 67.14
## DGAT2 5.49 4.57 3.71 3.37 6.36 3.35 7.05
## ZNF112 2.06 2.37 2.30 5.48 2.67 3.33 2.74
## CS 109.04 120.33 141.19 97.34 116.23 82.96 122.20
## LTK 0.02 0.02 0.00 0.00 0.02 0.35 0.08
## MRPS24 151.96 143.28 145.19 145.07 136.47 128.78 143.76
## ELMO2 23.42 32.29 35.19 25.30 23.23 19.07 27.57
## WAPAL 26.27 29.31 30.73 29.46 32.06 22.42 30.64
## VMP1 112.50 113.86 114.51 120.96 132.40 129.85 105.24
## APPBP2 5.12 8.04 8.49 5.43 6.65 2.97 6.48
## POLD1 31.75 30.19 30.36 72.05 33.79 46.45 31.55
## SEZ6 0.02 0.00 0.00 0.00 0.00 0.15 0.11
## EIF4B 185.07 268.74 280.53 139.11 195.10 92.37 174.21
## SLC6A16 0.39 0.09 0.38 0.00 0.84 0.56 0.26
## GLTSCR1 2.09 3.04 3.56 5.56 2.25 2.11 3.26
## SPHK2 5.87 8.00 7.55 6.38 8.28 4.17 14.33
## RPL18 2662.89 2413.14 2498.90 2079.13 2298.30 1926.06 2654.12
## CA11 8.43 5.21 9.73 6.16 5.43 6.15 4.59
## ISOC2 75.71 83.98 93.84 42.08 67.59 34.05 67.46
## U2AF2 81.65 91.00 100.85 129.73 95.02 73.97 110.66
## EPN1 42.40 56.06 65.93 59.26 44.77 29.09 54.13
## MED29 21.32 15.39 17.93 21.33 16.94 12.15 17.85
## AHRR 2.12 1.75 2.93 3.04 1.76 2.54 2.54
## GSC2 0.00 0.00 0.00 0.00 0.03 0.00 0.07
## ZNF275 1.97 3.06 3.49 2.06 2.54 1.36 2.65
## MTMR1 8.12 10.32 11.89 24.03 8.18 8.56 9.15
## GPC1 54.94 48.90 59.78 65.04 58.48 35.34 68.45
## ADCK1 4.29 3.89 4.92 5.26 4.22 3.34 5.28
## HAGH 31.65 38.55 38.74 17.14 26.16 13.52 20.98
## RNF4 21.56 29.26 36.44 26.23 24.80 18.03 29.74
## CASP8 13.24 13.32 15.90 16.64 16.35 11.79 13.20
## LIMCH1 6.10 13.92 6.62 15.01 9.67 6.74 9.45
## ASUN 53.05 67.48 61.64 37.78 52.57 32.81 45.36
## TM7SF3 52.95 57.29 54.45 36.12 61.64 22.67 54.65
## DLX3 3.67 2.16 2.90 2.28 3.40 2.34 3.83
## SPA17 10.56 7.70 5.94 6.45 8.29 12.72 7.80
## TSPAN32 0.00 0.03 0.00 0.00 0.00 0.00 0.34
## WISP2 0.00 0.02 0.00 0.00 0.00 0.00 0.00
## DMRT3 0.01 0.03 0.00 0.00 0.01 0.00 0.17
## ST3GAL6 1.59 1.59 1.83 3.80 1.27 2.63 2.44
## ATP2C2 5.00 6.03 8.14 8.86 5.15 4.19 6.18
## NGFR 2.82 2.79 3.19 2.20 4.56 2.02 4.57
## CDON 0.74 0.61 0.72 1.67 0.76 0.65 0.65
## TAF2 8.04 11.16 12.21 13.59 9.66 9.25 10.29
## HIPK2 3.67 4.40 6.28 2.32 3.71 1.69 2.98
## TNPO3 13.20 15.49 18.84 17.22 13.17 9.44 16.86
## MEF2BNB-MEF2B 5.31 6.06 6.05 9.25 5.87 4.98 7.32
## RFXANK 83.83 82.12 74.10 95.73 82.98 63.43 83.07
## TMEM161A 27.60 25.11 25.05 38.69 24.25 34.16 33.94
## LPAR2 14.41 16.80 22.03 18.26 17.17 10.37 20.06
## CTSA 71.84 61.86 74.51 96.79 69.97 69.42 101.73
## SUGP2 35.91 33.70 29.46 60.68 37.30 54.29 41.65
## SLC12A2 2.35 2.71 2.89 3.36 3.01 2.54 3.16
## SNX24 16.75 20.79 18.36 11.56 16.39 14.79 18.93
## EYA2 0.05 0.03 0.06 0.00 0.03 0.00 0.06
## CNN2 94.75 138.13 132.83 96.81 111.41 64.55 104.81
## ABCA7 6.43 6.37 6.09 4.06 5.87 5.26 6.02
## SNCAIP 0.13 0.16 0.10 0.06 0.12 0.02 0.25
## DDX20 11.82 11.87 11.88 15.40 11.52 11.90 12.38
## BTBD1 35.69 42.24 44.32 46.43 42.66 25.27 38.71
## FAR2 9.26 10.28 7.89 7.39 10.22 10.59 7.29
## BCAS1 0.00 0.01 0.00 0.00 0.02 0.00 0.01
## POU1F1 0.00 0.00 0.00 0.00 0.02 0.00 0.00
## CHI3L2 0.12 0.16 0.34 0.00 0.13 0.00 0.00
## SBNO2 25.58 30.43 40.21 49.33 28.99 28.10 36.76
## PMS1 13.44 14.62 13.72 17.99 13.25 16.00 14.13
## HMG20B 34.20 32.82 35.58 66.40 36.58 34.51 40.82
## CALCRL 0.17 0.09 0.01 0.00 0.07 0.02 0.13
## TAF11 34.62 31.99 32.63 33.42 34.95 32.89 37.90
## ANKS1A 5.42 6.79 7.81 6.37 5.14 4.42 6.00
## AP3D1 30.21 46.80 53.80 53.63 31.09 29.08 41.36
## ZNF76 10.53 12.51 11.18 14.90 11.46 8.46 15.32
## SLC9A3R2 35.58 35.98 41.97 32.55 31.57 20.49 32.17
## NTHL1 23.53 17.07 19.38 13.52 14.89 17.15 16.13
## UHRF1BP1 2.53 3.05 3.51 4.09 2.35 1.94 2.60
## GNAI3 65.96 78.38 78.08 52.94 81.32 35.06 69.43
## IPO5 47.33 70.83 65.17 72.15 53.46 41.55 51.63
## OAT 66.65 77.24 72.62 68.93 74.92 52.77 61.56
## WDR3 24.29 30.09 29.11 31.78 28.24 19.28 26.89
## PKN2 12.09 12.67 15.64 16.46 14.44 9.73 12.34
## WDR18 50.71 43.28 47.18 63.65 48.29 42.00 54.23
## TRAM2 6.45 8.85 8.36 8.16 9.71 3.92 9.48
## NTN1 0.49 0.85 0.70 0.16 0.85 0.02 0.53
## GLP2R 0.03 0.16 0.12 0.10 0.03 0.03 0.07
## MCM10 3.76 4.08 3.84 9.95 4.17 4.74 4.72
## DGKA 85.08 107.35 98.12 111.88 75.81 92.88 70.54
## ERBB3 7.25 5.11 7.92 8.58 4.89 4.59 5.12
## ROPN1 0.03 0.00 0.02 0.00 0.00 0.00 0.00
## ANKRD44 0.32 0.23 0.42 0.00 0.21 0.09 0.03
## KARS 202.93 215.20 216.28 195.38 210.02 152.29 210.13
## ADAT1 22.05 23.10 25.40 16.99 26.61 11.64 20.07
## PDIA5 20.86 30.26 31.56 28.55 19.57 13.90 17.82
## TBC1D22B 7.48 9.40 10.06 8.57 8.69 4.87 9.52
## NDUFB4 276.82 214.96 205.71 306.48 262.41 366.68 227.02
## SPEN 17.58 27.07 26.93 24.53 17.22 19.51 27.12
## MYLK 1.75 1.05 2.96 1.15 1.56 0.72 2.85
## ZC3H15 74.43 76.45 83.24 66.66 75.52 57.49 72.06
## MAP2K4 10.66 11.25 12.38 18.22 12.52 10.38 13.08
## TMEM206 8.95 12.06 11.31 17.47 15.13 10.02 14.89
## SNAP91 0.18 0.07 0.02 0.00 0.04 0.00 0.02
## SLK 22.00 22.39 26.59 35.07 26.10 17.71 23.46
## CYB5R4 15.28 17.16 17.79 17.71 17.94 10.53 18.37
## COL17A1 338.52 305.84 306.29 282.80 380.67 250.58 335.03
## GSTO2 77.96 56.41 49.74 33.52 75.92 53.72 59.73
## SEC61A2 4.72 5.01 6.30 11.97 6.07 4.47 7.18
## PRKCQ 0.32 0.37 0.27 0.40 0.20 0.24 0.31
## TLE2 3.21 4.08 4.79 2.45 3.02 2.20 3.84
## ASB1 75.63 131.47 100.29 76.83 111.93 62.02 110.98
## FAM107B 4.67 5.78 5.28 6.42 6.82 3.70 5.03
## ME1 15.30 9.51 12.18 16.42 19.75 12.08 21.02
## TBC1D1 13.75 17.32 16.33 11.91 14.87 9.89 12.43
## CDK13 10.91 11.16 15.06 18.88 12.56 8.54 13.35
## MTHFD2 198.50 335.27 343.51 169.20 252.24 119.53 196.05
## SLC9A7 2.94 3.24 4.25 1.94 2.60 2.13 2.54
## FOXJ2 4.25 6.21 6.87 4.70 5.41 3.29 5.88
## YBX1 857.89 884.74 863.93 717.63 880.99 653.77 869.87
## PDE4A 0.34 0.72 0.66 0.25 0.62 0.11 0.63
## PPP2R5A 23.00 20.32 23.75 19.83 23.38 13.46 21.55
## CTNNA2 0.00 0.00 0.00 0.00 0.00 0.00 0.07
## ELAVL1 38.99 43.66 45.70 36.70 44.17 27.98 46.79
## TIE1 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## DIP2B 7.74 9.97 9.65 10.65 10.31 6.22 9.52
## SMARCD1 30.49 31.68 34.21 46.78 30.11 28.83 40.92
## KDM4A 8.76 9.06 10.43 12.23 8.21 7.49 10.25
## NFYC 29.30 33.03 38.95 31.10 29.30 22.14 41.51
## ZMYND12 0.12 0.06 0.28 0.00 0.12 0.02 0.04
## SLC9A3 0.32 0.24 0.32 0.49 0.20 0.21 0.14
## NGEF 9.76 7.19 12.48 6.15 7.87 4.81 6.67
## ASPM 22.12 24.56 19.89 24.40 24.06 18.66 18.87
## CD84 0.00 0.00 0.00 0.05 0.00 0.00 0.00
## ELOVL1 116.42 141.24 134.06 104.94 123.58 83.26 133.21
## SPI1 0.04 0.00 0.00 0.00 0.00 0.00 0.11
## ZNRD1 75.25 64.66 58.97 66.12 69.10 87.69 72.55
## MPPED2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CLDN18 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZBTB11 9.58 11.65 13.37 12.87 12.88 9.06 11.05
## ATXN3 26.64 29.66 29.88 17.28 27.79 11.31 22.86
## GOLGA5 36.20 43.99 56.30 34.55 39.34 22.64 31.03
## FGFR2 6.08 7.42 8.97 7.78 6.84 5.28 6.66
## LRRC40 11.10 11.80 11.55 13.20 14.55 10.38 11.85
## ISOC1 11.95 11.15 11.11 14.54 11.09 8.04 9.93
## EML1 0.36 0.47 0.46 1.54 0.39 0.40 0.26
## TRMT11 26.68 32.39 27.12 23.60 25.41 19.20 18.18
## THUMPD1 17.81 20.16 21.82 19.42 19.65 11.64 16.02
## MSANTD3 38.18 47.92 43.19 46.36 53.56 36.51 59.65
## KIF26A 0.32 0.39 0.60 0.56 0.38 0.22 0.25
## ATG2B 2.49 2.73 3.41 4.27 2.92 3.17 3.00
## ARFGEF1 14.38 20.37 21.85 20.28 19.35 8.60 18.00
## ACSM2B 0.00 0.00 0.00 0.00 0.00 0.00 0.97
## ZFAT 3.80 5.49 5.29 5.15 4.98 2.87 5.40
## MTFR1 25.03 33.41 35.08 21.19 26.77 17.05 22.16
## STAG3 7.14 5.82 6.87 13.71 7.01 6.86 5.84
## FECH 5.20 4.14 5.29 5.47 5.44 3.98 6.08
## MYO9A 3.32 3.58 4.82 4.42 4.19 2.60 5.13
## DDX3Y 0.02 0.02 0.00 0.00 0.01 0.01 0.01
## PFKP 97.84 107.96 107.32 131.43 115.54 97.26 151.93
## IDI1 59.90 97.26 81.90 90.88 85.13 76.78 64.20
## SP100 25.10 26.75 27.11 24.25 34.26 20.04 25.25
## KLF6 47.39 55.15 67.97 48.10 56.57 38.25 54.42
## PPAP2A 8.63 9.28 9.80 2.40 8.51 3.71 7.79
## NEO1 2.16 1.05 2.28 0.74 0.86 1.43 1.26
## TRAM1 80.81 153.82 196.16 67.65 93.83 37.24 62.28
## PHKA1 2.98 2.53 2.74 3.22 2.27 2.34 2.45
## TNFRSF1A 53.31 61.16 69.47 54.41 56.73 34.79 66.74
## CACNB1 4.97 8.53 8.85 6.96 5.82 5.70 6.47
## EVI5 1.82 2.59 2.96 2.61 2.01 2.20 2.16
## STOML1 5.51 4.47 4.30 10.05 5.29 6.10 8.01
## PKM 906.64 803.36 872.84 1143.23 897.29 750.94 1124.29
## DHX29 16.96 17.23 17.46 25.82 17.95 16.37 18.08
## DNTTIP2 87.69 83.58 78.38 132.08 108.36 90.79 103.97
## METTL22 14.48 17.62 19.70 18.87 17.09 16.63 20.83
## TP53BP1 10.39 11.08 11.57 20.76 9.98 12.76 10.37
## TRO 0.03 0.04 0.05 0.00 0.06 0.47 0.14
## RRP15 19.22 27.35 21.95 22.60 24.76 18.72 22.40
## RHOA 251.19 275.03 301.77 195.90 295.30 157.12 254.50
## DHX8 19.31 22.61 25.68 27.39 18.61 15.60 22.55
## PRKCZ 17.20 20.21 23.09 14.09 17.00 8.48 15.93
## ZFY 1.22 1.45 2.13 2.50 2.38 1.23 1.74
## IARS2 63.81 77.98 72.12 85.94 70.02 52.64 67.86
## SYT1 0.10 0.38 0.60 0.06 0.17 0.24 0.25
## NAV3 0.57 0.95 0.51 2.06 1.77 3.49 2.16
## IDH3G 37.67 35.03 38.85 45.21 36.02 35.95 41.03
## ROGDI 20.07 14.69 15.89 18.20 15.90 13.72 16.64
## PDZD4 0.13 0.13 0.22 0.13 0.13 0.09 0.11
## ATP2B3 0.00 0.01 0.00 0.00 0.01 0.00 0.00
## ROCK1 11.04 13.12 14.14 18.90 12.65 9.16 11.01
## CBFB 31.14 29.45 33.22 31.72 42.03 21.17 30.55
## PDK3 1.50 1.24 1.33 1.06 1.76 1.35 1.29
## HYAL2 22.69 21.47 24.34 21.92 17.38 17.88 17.26
## HDAC4 3.49 3.80 3.29 3.79 2.29 1.29 2.46
## RASSF1 23.00 27.17 29.14 30.15 27.14 18.22 32.30
## FGFR3 16.87 8.51 17.33 16.47 11.84 9.36 9.31
## IFI35 14.69 9.58 11.54 11.74 17.00 8.56 16.14
## HEATR6 8.52 11.46 9.06 9.26 9.57 5.57 7.93
## COASY 88.16 89.33 96.01 63.23 72.05 64.15 63.46
## PLEKHH3 32.46 25.56 34.19 26.76 24.26 15.29 25.47
## MEF2A 18.20 17.92 29.48 18.92 22.10 9.61 18.19
## OTUD5 22.44 26.02 32.86 30.23 23.05 18.75 26.81
## TFE3 21.66 27.83 29.53 25.72 27.32 17.26 33.58
## TBC1D25 7.12 9.83 10.38 9.39 5.48 4.63 6.36
## ACSL4 13.27 17.31 14.84 26.54 22.22 17.30 18.86
## INPP5A 6.53 6.41 7.03 4.27 8.26 3.82 7.59
## GPKOW 23.65 22.88 24.62 23.98 22.64 15.43 24.50
## GRIPAP1 14.32 16.48 19.52 12.83 13.20 15.11 15.41
## FTSJ1 105.93 139.71 130.69 85.02 119.07 78.60 111.49
## PRR11 7.39 9.14 8.99 8.03 8.77 3.08 6.38
## REEP1 0.03 0.00 0.11 0.00 0.07 0.05 0.09
## ATP11A 2.61 2.69 3.59 2.12 2.79 2.08 3.18
## POLR1A 5.10 5.92 6.96 8.95 5.61 4.05 6.73
## LAPTM4A 143.83 190.91 182.11 96.70 160.73 86.10 130.83
## TTC7A 11.66 15.26 14.88 10.68 11.77 7.93 12.42
## IP6K2 43.92 40.52 49.75 55.66 39.17 48.50 43.59
## STON1-GTF2A1L 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SRBD1 5.37 6.18 5.76 11.21 6.85 4.48 6.08
## CYFIP1 50.56 57.92 60.33 61.24 49.99 39.98 56.52
## KIF2A 20.20 27.22 24.65 19.62 20.94 12.74 20.21
## RASGRP2 0.39 1.73 0.80 0.00 1.30 1.25 0.77
## PSME4 30.40 38.78 38.81 41.81 43.72 25.56 34.25
## IFT80 6.21 7.06 7.63 5.21 7.55 7.06 6.86
## SIRT2 20.78 18.40 26.22 19.71 17.87 11.23 22.39
## ERLEC1 41.36 60.46 65.55 17.09 44.76 17.24 27.63
## PPP2R5B 9.72 13.06 12.99 10.19 11.09 6.35 13.65
## PYGM 0.21 0.21 0.15 1.04 0.28 0.40 0.28
## PAGE1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PITX1 54.59 35.65 79.58 36.63 34.61 26.90 37.56
## TRPC7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MAST4 9.38 8.28 10.72 3.97 9.95 4.84 6.06
## GPR116 0.00 0.00 0.00 0.00 0.00 0.00 0.02
## SDK2 0.01 0.12 0.03 0.00 0.06 0.06 0.02
## ADAM7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NUP133 16.40 16.11 15.16 29.22 20.47 16.39 16.71
## NUCKS1 95.16 87.75 89.10 47.35 99.05 44.23 60.17
## VPS35 41.15 47.72 51.43 50.31 42.31 27.08 43.11
## DNAJA2 62.25 69.31 71.13 48.76 70.97 41.43 63.06
## BCL3 15.03 19.85 27.66 16.84 16.55 11.96 15.51
## KCNAB2 8.20 9.42 9.02 8.65 10.93 8.21 12.00
## ABCC9 0.00 0.00 0.00 0.00 0.00 0.01 0.03
## GAL 23.53 16.53 15.69 25.06 20.54 23.62 27.79
## CLEC2D 2.11 2.17 2.21 2.93 1.64 2.28 2.29
## FUNDC1 16.30 17.56 14.44 14.51 17.50 11.55 13.07
## MAOB 0.16 0.06 0.21 0.09 0.02 0.00 0.06
## RORA 0.89 1.43 2.40 0.35 1.21 0.18 0.67
## DRD4 1.12 1.16 0.77 0.38 1.32 0.45 1.84
## TGFBR3 0.73 0.61 0.79 0.63 0.79 0.71 0.78
## KIAA1107 0.22 0.16 0.26 0.29 0.19 0.08 0.22
## PLA2G10 0.19 0.13 0.11 0.00 0.13 0.00 0.00
## HES2 50.89 59.00 62.72 34.03 58.38 26.66 44.96
## ATP1B3 243.68 243.87 219.23 215.88 245.53 176.43 244.42
## NEDD4 6.48 8.94 12.14 11.80 8.49 5.72 10.47
## PIGB 10.16 11.38 9.88 13.20 10.14 6.98 8.91
## MAPK6 71.66 85.33 102.45 78.81 94.18 45.61 82.15
## GNB5 21.11 24.86 27.78 16.71 21.80 15.07 22.75
## RAB27A 18.84 27.79 29.97 19.61 24.12 9.86 20.13
## CECR5 31.13 30.49 31.91 42.79 31.71 31.56 40.25
## UFD1L 73.57 68.88 73.80 60.15 74.65 62.71 87.77
## LRP6 3.03 3.81 3.67 4.88 3.58 2.49 3.55
## GUCY2C 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## SCT 0.00 0.00 0.12 0.00 0.00 0.00 0.00
## PHRF1 8.99 9.11 10.62 19.86 7.99 12.39 10.99
## IKBKAP 28.70 28.84 31.14 66.00 28.01 35.60 30.21
## NUCB2 74.77 106.67 118.40 28.96 53.33 34.07 39.89
## PFN2 40.79 33.19 33.61 29.31 40.09 29.52 40.66
## PTPN3 12.71 15.31 16.64 20.14 15.47 12.54 16.85
## SPTB 1.36 0.66 1.04 0.59 0.70 1.60 0.72
## DAPP1 16.60 30.94 34.03 21.01 26.18 11.27 29.79
## FGF10 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SLC44A1 9.77 10.97 13.70 5.91 9.81 5.08 8.47
## TMEM260 5.35 7.26 7.56 6.42 5.65 4.21 5.62
## SMG6 14.06 16.45 18.54 19.40 19.44 11.97 21.11
## EXOC5 15.54 19.07 20.61 17.74 19.60 6.98 12.92
## CLTCL1 1.73 1.82 1.45 3.46 1.80 3.52 2.96
## FGF22 0.04 0.00 0.06 0.11 0.23 0.00 0.27
## FSTL3 68.08 88.15 82.56 75.30 80.08 52.72 83.07
## DGCR2 16.71 15.73 21.65 17.59 16.26 9.73 19.52
## RNF126 58.75 79.96 88.97 67.35 59.30 52.42 67.13
## MNT 8.87 12.78 19.01 9.91 10.00 6.19 10.18
## ZXDC 9.79 9.80 11.50 16.07 9.30 9.20 12.81
## JMJD6 36.88 40.13 39.24 56.04 45.92 39.91 44.55
## POLB 25.98 27.22 24.17 22.13 27.38 19.86 24.63
## ST6GALNAC1 0.07 0.08 0.20 1.26 0.25 0.00 0.05
## WIPI1 16.58 35.35 42.91 11.25 17.40 6.63 17.02
## FRMPD1 0.01 0.02 0.23 0.00 0.02 0.00 0.06
## GBA2 48.22 51.48 60.94 89.23 45.01 73.71 59.53
## NDST1 18.25 20.58 28.98 13.56 16.21 8.32 15.57
## ASNS 186.86 251.54 236.24 154.78 197.82 124.62 228.93
## AP3M2 10.57 9.79 10.27 14.74 9.32 10.07 9.55
## CNGB1 0.12 0.01 0.12 0.00 0.30 0.01 0.00
## ST6GALNAC2 17.37 18.30 19.80 9.97 13.86 7.72 13.10
## CHAT 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PABPC1 748.02 1009.23 1072.65 773.84 856.45 547.43 858.50
## TESK2 2.41 4.36 4.34 1.77 2.54 1.37 2.30
## C16orf80 28.55 33.17 34.09 33.19 33.11 22.85 35.24
## CSNK2A2 42.95 55.00 64.98 42.03 50.45 22.32 47.65
## PTPN21 3.28 4.59 4.32 3.88 4.70 3.44 6.50
## EIF2B3 28.40 23.73 23.08 34.19 25.91 24.10 29.63
## CAMK2A 0.46 0.46 0.60 0.02 0.18 0.16 0.09
## TCOF1 52.60 62.00 61.42 89.80 53.12 57.24 62.46
## CDC42 172.98 160.66 162.53 129.78 172.55 122.70 159.70
## OSBPL3 15.54 21.08 20.26 21.16 21.66 13.28 18.83
## EPHA8 0.00 0.00 0.03 0.30 0.02 0.00 0.00
## SLC12A3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RAD18 9.26 11.96 11.70 7.08 13.23 4.75 9.51
## ATP2B1 12.65 18.39 26.46 23.73 13.08 12.98 16.88
## TRPM5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NCK2 18.36 23.01 26.25 20.41 18.81 13.92 17.06
## MAP4K4 33.28 33.22 38.39 33.43 31.18 22.70 31.23
## MGAT4A 0.51 1.05 1.16 1.41 0.90 0.68 0.76
## RPL31 3798.09 3507.99 3300.87 3787.08 3188.10 5601.85 3202.03
## WDR1 78.01 93.28 97.92 114.68 104.88 65.93 121.88
## SNX13 8.45 9.99 11.04 11.30 9.01 6.18 9.18
## MS4A12 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ARHGAP10 7.89 6.99 8.03 12.97 8.03 6.50 10.13
## RPS6KA2 11.21 19.23 20.23 9.21 14.56 5.16 16.22
## ING3 12.28 14.04 15.78 12.04 14.04 11.50 13.60
## VASH1 0.11 0.05 0.16 0.19 0.18 0.24 0.21
## LMCD1 2.83 4.76 4.85 2.52 3.18 1.88 2.93
## WBSCR22 120.58 135.62 117.57 102.33 134.58 91.91 138.54
## SEL1L 17.51 31.24 45.05 11.83 19.44 6.46 14.69
## TRIP13 26.58 29.62 27.95 33.52 24.01 25.85 23.57
## ATP6AP1 42.66 48.46 54.50 40.47 44.10 26.21 50.19
## TCF3 64.48 79.88 82.39 84.83 71.37 60.87 70.03
## TRIB2 17.60 22.13 22.00 7.84 13.02 8.14 7.35
## DAZAP1 180.03 219.49 205.77 213.49 204.32 128.89 194.33
## MBD3 33.52 35.45 34.56 56.87 34.36 28.84 46.16
## PRLH 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## HLTF 12.14 11.91 13.34 15.27 12.23 9.15 9.24
## FAM50A 82.21 92.27 94.52 118.00 79.13 73.89 104.00
## FAM3A 26.49 26.70 27.36 36.10 25.80 23.42 30.94
## CPSF1 83.96 77.91 92.52 149.11 86.58 100.49 92.41
## MYO3B 0.00 0.00 0.02 0.00 0.00 0.00 0.00
## CYBRD1 19.41 27.06 26.11 19.80 25.08 11.86 19.19
## CDH19 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PDCD2 113.66 105.19 104.57 87.00 105.90 83.21 100.46
## SLC6A15 33.56 39.69 40.02 29.31 35.31 24.43 28.32
## RDH11 47.08 55.00 51.40 59.14 47.84 43.44 50.44
## PRKACA 21.68 27.68 35.36 19.59 21.83 12.07 25.74
## LPHN1 0.75 1.00 1.58 2.19 0.76 0.65 1.11
## SPP2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ACTN1 98.72 124.24 111.54 152.01 123.17 98.54 142.53
## ZFYVE26 3.73 3.77 4.80 4.97 3.15 3.34 4.63
## RPS6KA6 0.01 0.02 0.00 0.18 0.01 0.00 0.07
## EPN2 14.57 16.32 18.80 13.64 16.20 10.10 14.08
## PTPN18 18.83 17.22 18.17 7.73 14.64 9.50 15.42
## LIMS2 0.36 0.40 0.54 0.25 0.22 0.07 0.26
## ASIC4 0.01 0.03 0.07 0.00 0.22 0.00 0.04
## SPEG 10.67 7.60 7.39 13.08 6.65 12.11 7.66
## LNX1 0.45 0.35 0.65 0.83 0.65 0.22 0.46
## ALDH3A2 103.20 76.43 112.64 112.75 102.51 68.98 98.41
## TFRC 37.45 54.56 53.90 85.73 60.31 50.65 81.00
## SREBF1 83.95 90.71 121.32 115.16 77.03 79.52 86.95
## TRPC5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## AFF4 15.30 21.10 25.08 19.94 21.72 10.96 20.08
## UBE2D1 15.56 14.81 15.97 14.84 19.55 15.88 15.99
## MPP5 8.18 8.08 9.65 10.18 8.48 5.08 7.90
## RHOBTB1 0.59 0.53 0.43 0.66 0.39 0.75 0.30
## SMC1A 9.12 10.71 12.29 16.49 9.77 9.97 9.63
## HSD17B10 97.27 76.47 75.18 127.97 93.87 94.38 131.65
## MARK2 11.33 14.22 18.39 13.40 12.48 8.25 13.14
## HMMR 17.53 18.90 19.11 21.46 20.35 10.56 15.55
## CHFR 13.11 14.44 17.20 16.99 10.51 11.63 14.76
## TRHDE 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## P4HA2 65.61 86.16 96.47 58.46 59.55 35.52 63.17
## FCGR2B 0.00 0.00 0.02 0.00 0.00 0.05 0.05
## NFATC3 3.01 3.04 4.11 3.33 3.59 2.47 3.26
## TRNT1 13.47 17.61 16.16 15.40 14.80 11.77 13.28
## ACADVL 269.97 349.43 498.12 695.08 262.73 468.99 405.16
## STK10 15.31 21.96 26.62 27.71 19.81 20.44 31.89
## FBXW11 22.93 34.64 35.51 23.58 28.11 15.24 22.94
## ACAP1 3.90 6.66 3.63 2.52 7.45 9.44 4.25
## CRMP1 1.43 2.12 2.24 3.05 1.88 1.54 3.50
## EVC 4.68 7.61 7.89 5.94 6.50 3.17 8.39
## DERL2 71.70 87.13 92.62 45.17 75.20 53.13 68.69
## SIDT1 0.05 0.04 0.05 0.00 0.01 0.08 0.01
## NDE1 27.97 33.93 37.15 20.01 30.00 12.60 27.08
## MRVI1 0.04 0.01 0.06 0.04 0.05 0.03 0.04
## TMEM38A 8.90 8.90 10.15 10.18 8.30 4.84 9.69
## AP1M1 26.11 28.46 32.92 26.99 26.25 20.83 33.48
## PVR 36.89 56.97 52.89 53.09 46.14 30.17 57.89
## IKBKG 24.99 23.44 27.64 51.57 28.56 32.61 44.51
## XRCC1 17.30 18.86 20.21 23.63 14.27 11.80 13.55
## SCARB1 37.81 49.70 44.22 50.33 38.09 37.14 46.82
## CYP2W1 0.00 0.00 0.02 0.00 0.01 0.00 0.01
## MCM2 32.44 30.21 33.34 58.55 33.28 32.96 43.58
## MOV10L1 1.85 1.59 2.11 2.63 2.77 2.78 1.83
## PANX2 2.67 2.81 5.77 2.72 2.92 1.93 3.36
## SELO 16.81 17.83 22.11 26.53 18.04 20.91 23.90
## TP63 48.58 44.14 47.40 45.93 49.02 35.63 44.32
## ALPK1 5.66 7.90 9.50 5.93 6.19 3.88 6.58
## LLGL2 43.72 43.37 49.00 45.56 43.80 25.14 52.86
## PDE8A 8.77 10.90 11.22 10.75 10.33 8.58 10.17
## CLCN4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NLE1 25.54 34.32 32.54 19.66 24.25 19.87 28.65
## SDHA 142.76 133.10 123.54 143.98 139.27 136.39 118.75
## SMARCE1 94.95 98.60 99.70 95.48 91.31 61.31 92.43
## FNDC8 0.04 0.06 0.00 0.00 0.06 0.00 0.03
## GSDMB 5.71 5.62 6.61 3.62 4.15 5.40 4.92
## KDM5A 5.71 5.75 7.53 10.61 6.74 2.80 7.82
## ADAM11 0.22 0.26 0.32 0.12 0.43 0.16 0.29
## PPP2R3A 1.32 1.69 1.51 1.76 1.76 1.00 1.67
## FERMT2 12.82 16.17 14.52 17.92 18.51 12.62 19.49
## ABCB11 0.00 0.00 0.00 0.00 0.00 0.00 0.03
## DHRS9 1.56 0.46 1.95 0.44 0.26 3.17 1.36
## CD5L 0.00 0.00 0.01 0.08 0.00 0.00 0.16
## PTGS2 0.87 2.64 2.46 2.59 4.44 1.40 2.19
## IGF2BP2 35.82 50.43 48.79 36.90 41.08 28.83 37.76
## MAP3K13 15.73 12.30 13.65 14.89 18.96 18.01 17.38
## ST6GAL1 2.44 3.41 3.87 1.09 1.94 1.43 1.86
## TBX21 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## FRY 0.14 0.48 0.37 0.11 0.24 0.09 0.28
## PICALM 64.53 76.23 80.34 69.17 78.82 42.96 70.64
## NSF 4.55 4.56 5.08 6.99 5.22 3.52 5.86
## GLI2 0.11 0.14 0.23 0.11 0.10 0.15 0.05
## CLASP1 6.51 6.43 8.47 7.09 6.56 5.96 7.38
## MRPS34 111.03 94.45 101.19 108.13 97.12 101.58 87.80
## NOTCH3 10.65 13.31 18.95 3.68 7.62 2.49 7.54
## CLNS1A 189.08 182.29 180.19 141.29 167.82 129.70 141.87
## PPP2R2C 2.20 1.68 3.22 1.16 1.51 1.57 1.70
## TEAD2 14.49 13.35 18.67 17.49 11.68 10.29 13.40
## EED 25.36 23.71 23.75 23.51 23.49 24.99 23.42
## CDHR2 0.12 0.15 0.10 0.00 0.14 0.02 0.11
## SNCB 0.10 0.10 0.37 0.00 0.28 0.00 0.05
## TSG101 110.46 117.68 119.94 60.30 117.78 60.93 113.63
## C17orf85 14.07 17.57 17.31 15.32 14.97 15.72 16.43
## ATP2A3 0.16 0.21 0.07 0.05 0.03 0.16 0.02
## CA12 12.71 5.98 11.94 10.10 8.28 6.50 8.24
## MGLL 11.69 28.65 27.24 18.28 17.44 10.03 24.03
## NTN4 21.56 39.81 44.62 19.37 23.95 8.93 21.09
## BCS1L 52.59 39.60 38.18 91.73 42.53 102.91 58.65
## NUAK1 1.62 1.64 1.97 1.47 1.29 0.70 1.24
## DPP8 14.34 16.21 20.52 16.28 18.44 14.26 14.15
## SLC24A1 2.99 3.76 2.83 3.27 2.94 3.39 2.92
## ZNF532 7.00 7.65 10.91 7.74 7.54 6.12 7.02
## SCARF1 0.24 0.37 0.47 0.08 0.36 0.21 0.55
## LMAN1 23.15 41.60 57.08 19.34 24.38 11.78 17.36
## PTPLAD1 63.50 68.54 66.90 49.11 67.38 39.92 56.69
## IPCEF1 0.03 0.00 0.01 0.00 0.00 0.00 0.00
## ZZEF1 4.51 5.31 6.62 5.76 4.68 3.23 6.00
## NOX3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ENO1 1495.27 1370.18 1406.35 1880.39 1452.84 1394.08 2023.45
## SLC12A1 0.00 0.00 0.00 0.01 0.07 0.01 0.00
## C19orf10 214.91 295.25 301.56 128.94 219.80 119.73 216.20
## ANO8 2.66 2.38 3.88 2.85 2.14 1.47 3.27
## TUBE1 7.91 9.44 8.91 13.79 7.79 10.96 11.41
## ARHGEF10L 3.81 3.14 4.35 3.40 2.52 2.49 3.06
## TXK 0.00 0.00 0.00 0.23 0.02 0.15 0.00
## WSCD2 0.11 0.20 0.36 0.00 0.05 0.00 0.05
## KCNQ2 0.23 0.16 0.59 0.00 0.21 0.00 0.00
## TACR2 0.10 0.07 0.17 0.19 0.04 0.00 0.15
## ACTR6 21.70 23.63 21.20 26.06 28.05 17.17 20.71
## TIPIN 32.56 35.39 26.86 30.80 44.54 29.87 39.47
## SRI 117.77 95.70 86.97 132.91 94.91 133.94 104.65
## EIF4G3 14.58 19.84 23.15 21.96 15.62 11.06 17.32
## NUP37 69.17 67.86 59.40 54.10 70.40 59.81 63.15
## SEMA3A 1.74 1.49 2.01 1.49 1.66 1.10 1.05
## GTSE1 3.95 4.74 4.38 4.23 3.49 3.37 4.06
## SEMA3C 9.35 11.85 15.60 10.96 12.91 7.69 10.49
## TTC38 4.71 4.52 4.21 7.72 3.81 2.87 5.58
## ACAT1 58.86 65.07 55.67 53.38 53.58 53.11 55.39
## GRAMD4 4.55 5.13 7.76 4.31 3.56 5.48 3.58
## CELSR1 20.89 20.29 23.42 22.33 22.34 14.22 24.20
## WNT8B 0.01 0.03 0.05 0.00 0.04 0.00 0.04
## ZNF638 57.25 54.47 61.55 88.44 65.94 57.27 54.68
## SLC25A40 8.89 12.14 9.99 5.06 7.34 6.53 6.68
## TIMM21 38.95 37.70 38.32 36.51 40.11 34.37 38.57
## ADD2 0.06 0.08 0.02 0.09 0.22 0.14 0.17
## FGF4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RASAL2 2.92 3.92 3.81 4.20 4.85 3.35 4.61
## VPS9D1 3.80 3.98 5.08 5.69 4.16 3.80 5.12
## ZNF37A 6.21 8.94 9.73 6.84 6.63 4.46 6.27
## MARK3 51.58 54.27 61.43 62.77 56.87 48.84 55.27
## SLC25A3 539.54 533.71 467.58 442.62 578.90 457.98 542.40
## FNDC3B 11.55 16.81 22.02 10.33 15.93 8.18 10.46
## FOSL2 28.55 25.75 47.87 26.32 28.74 17.73 32.70
## CACNG5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CACNG4 1.20 1.18 1.10 1.11 0.84 0.66 0.74
## FRYL 10.89 12.91 11.91 19.92 17.86 9.69 14.37
## TMEM131 8.24 9.64 12.37 9.93 10.99 6.09 10.62
## FSCN1 256.34 267.10 304.44 228.77 278.61 147.88 238.77
## ACTB 2636.77 2534.95 1815.94 1871.92 3376.56 1987.76 2554.48
## MOCOS 20.62 24.00 25.31 9.80 24.85 12.98 23.01
## PLD1 3.29 2.63 3.77 2.88 1.95 2.36 1.08
## ATP12A 0.03 0.05 0.07 0.00 0.01 0.10 0.00
## WDR62 4.94 6.06 6.26 10.89 5.14 6.91 7.45
## DLG1 22.11 31.67 29.75 35.38 27.22 20.55 25.09
## RAB7A 200.86 221.78 244.96 206.25 249.11 112.70 249.29
## BCAP29 36.22 34.61 45.13 31.19 33.40 25.63 33.31
## SEC31B 2.35 3.11 2.28 3.63 2.19 2.93 2.61
## SART3 23.20 27.87 31.53 33.80 24.56 24.50 32.47
## ARHGAP15 0.00 0.00 0.00 0.00 0.00 0.00 0.34
## TUBA3D 0.00 0.00 0.04 0.00 0.00 0.00 0.00
## PAX2 0.01 0.00 0.01 0.00 0.01 0.00 0.00
## EXOSC7 73.25 82.80 70.92 75.54 75.47 61.38 75.54
## KIFAP3 15.73 14.09 14.99 13.14 12.81 11.20 10.73
## MKRN2 13.93 15.05 17.07 14.03 14.59 10.53 13.93
## MCM6 32.17 29.30 26.24 58.65 36.46 37.78 36.31
## REXO2 103.48 124.87 112.65 100.85 108.47 113.66 106.60
## RBM7 26.15 26.78 28.69 18.11 30.93 21.55 23.90
## RBMS2 2.01 3.72 2.79 3.01 2.96 2.05 1.64
## BAZ2A 14.76 19.00 24.12 14.93 13.86 11.72 13.16
## PTPN23 7.46 10.92 16.14 10.03 8.11 6.90 11.27
## MLH1 20.87 22.39 27.32 18.57 20.03 14.80 22.40
## UNG 32.13 35.16 31.49 25.72 35.17 24.98 27.53
## FMO4 1.72 2.46 1.61 0.45 2.92 0.34 1.89
## KLHL20 8.03 10.70 11.80 6.82 8.72 6.66 9.18
## RGS11 1.67 1.55 1.66 1.51 0.85 1.74 1.70
## SLC46A1 4.54 5.53 5.70 5.04 3.27 2.47 3.69
## PLXNA2 10.39 14.91 14.53 11.66 10.69 11.28 11.09
## SPAG5 10.69 11.04 12.29 14.87 10.56 8.96 9.52
## ANKRD13A 21.84 17.30 18.56 22.87 28.21 15.66 23.90
## TPD52 57.68 63.33 68.06 42.34 60.73 40.27 56.84
## ACACB 0.52 0.55 1.58 0.53 0.35 1.41 1.27
## TRAF4 44.07 43.73 43.97 84.32 50.26 62.23 71.37
## PAG1 2.71 4.23 4.06 2.32 2.32 0.94 1.75
## GPATCH1 5.44 5.25 7.36 7.07 4.83 4.70 5.73
## ICAM3 8.24 8.16 6.44 7.00 6.70 11.80 9.55
## NT5C2 33.63 44.60 46.36 35.48 42.40 20.66 37.67
## MCAM 1.35 1.62 1.58 0.75 1.48 1.01 0.93
## GPC4 0.05 0.11 0.12 0.00 0.13 0.02 0.04
## MBNL3 0.89 0.89 0.81 0.59 1.13 0.55 0.71
## CAMSAP3 4.52 4.56 6.88 8.94 3.98 4.33 5.52
## RAP1GAP 5.92 5.34 8.60 2.91 4.06 2.13 3.47
## XAB2 33.72 37.07 42.69 37.95 35.08 26.63 40.35
## ARHGEF1 100.52 96.96 109.11 139.43 108.42 84.75 122.21
## STXBP2 60.74 64.26 70.68 72.35 63.85 42.04 77.43
## MAP2K7 17.82 22.73 27.22 25.69 19.08 18.21 23.44
## NMRK2 0.03 0.00 0.00 0.03 0.00 0.00 0.00
## DGKD 13.79 19.23 21.50 17.53 15.47 10.98 17.70
## CTTNBP2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ACTL6B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RARB 0.00 0.00 0.05 0.18 0.03 0.08 0.04
## TOP2B 23.63 25.46 25.36 36.96 30.81 22.19 25.18
## TM9SF3 59.99 79.73 87.74 54.28 80.47 35.90 61.84
## NFKB2 31.64 36.30 41.00 54.71 43.57 29.77 53.45
## UBE2T 132.58 122.18 102.95 120.37 125.38 167.44 97.51
## PPP1R12B 2.16 3.34 3.52 2.02 1.99 1.45 2.47
## DNAJC10 37.37 52.22 59.30 40.70 38.90 28.66 38.50
## GTF3C1 29.40 26.62 30.31 49.36 26.04 32.03 35.28
## IL4R 36.23 37.61 42.60 32.39 38.86 27.39 37.27
## USP33 17.16 15.63 17.44 22.88 18.93 15.87 17.13
## PAK3 0.00 0.00 0.00 0.00 0.00 0.00 0.07
## CAPN6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DCX 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## SNRPA 66.15 69.40 66.61 88.69 60.28 66.04 73.44
## SPAG6 0.07 0.00 0.00 0.00 0.00 0.00 0.05
## EXOSC5 57.65 67.79 67.97 52.03 48.73 37.30 56.71
## DYNC1I2 62.74 68.45 69.46 59.45 63.96 42.65 62.83
## APBB1IP 0.02 0.00 0.00 0.00 0.06 0.00 0.02
## LRCH4 14.81 18.09 21.05 30.91 16.73 22.54 20.57
## FAM76B 13.99 16.27 16.53 15.80 16.12 6.81 14.70
## SIRT6 27.63 26.20 34.99 52.22 35.23 28.12 46.06
## TYR 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## POLD3 11.18 8.98 10.51 14.30 9.37 10.73 9.95
## ACTN2 0.58 1.71 1.04 1.01 1.33 0.54 1.51
## CAPZB 126.79 132.45 140.56 125.34 143.68 90.78 155.44
## GPR137B 6.54 7.02 9.16 5.68 8.98 3.40 7.02
## NAALAD2 0.19 0.24 0.22 0.25 0.19 0.33 0.17
## JADE1 6.55 5.60 7.27 7.26 6.74 4.74 5.36
## SLC25A43 18.79 21.79 25.62 17.63 20.20 12.43 20.14
## UBE2A 73.85 74.05 74.44 64.72 83.02 53.35 73.10
## FGFR1 2.24 2.20 2.73 7.93 2.94 4.59 3.05
## FKBP6 0.11 0.13 0.14 0.02 0.06 0.05 0.14
## GTF2I 41.18 40.93 51.77 44.08 35.34 33.55 32.91
## SMC1B 0.11 0.04 0.08 0.02 0.07 0.00 0.04
## FBLN1 22.27 18.26 24.08 13.45 20.29 11.80 16.64
## ITGA8 0.01 0.00 0.00 0.00 0.00 0.00 0.00
## CST7 0.00 0.04 0.00 0.00 0.00 0.17 0.19
## MAP2 1.52 2.39 3.10 3.03 2.50 1.31 2.82
## PIAS2 3.56 4.12 4.75 8.87 4.21 2.68 3.93
## AMPH 0.00 0.05 0.03 0.00 0.02 0.00 0.00
## ARAF 31.43 34.15 41.84 30.81 31.15 24.03 32.64
## MCCC1 8.77 10.05 8.53 11.02 7.05 11.54 11.13
## LAMP3 12.87 33.60 41.61 6.63 18.97 3.77 19.36
## FAP 1.02 2.01 0.77 0.51 0.98 0.82 1.01
## NEBL 0.51 0.65 1.10 0.41 0.62 0.17 0.46
## ACER3 9.35 9.55 8.99 16.67 8.76 6.66 8.37
## UBE2K 102.86 109.43 104.56 72.08 106.97 71.47 108.91
## PIK3C3 27.82 29.45 33.83 26.55 28.05 23.35 29.82
## N4BP2 0.98 1.38 2.22 1.19 1.29 0.53 0.94
## C12orf5 36.17 57.66 53.66 19.06 51.92 17.03 37.35
## TULP3 7.64 12.24 14.84 9.23 8.29 5.61 9.46
## SYNJ2 6.69 7.54 8.14 13.25 9.73 8.54 10.26
## ADCY2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PPP2R5C 82.45 82.36 83.13 72.40 89.66 57.85 72.87
## RBFOX1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GNB1 192.78 239.41 251.65 192.46 197.68 123.17 204.65
## HOXA9 48.79 49.90 52.42 40.22 51.31 35.33 37.85
## EDN1 3.33 7.21 7.20 2.67 7.98 3.51 6.51
## MLLT10 13.96 19.02 17.78 18.40 14.50 11.07 14.69
## ZCWPW1 6.37 4.20 4.30 4.02 4.74 6.92 6.02
## ADCYAP1R1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## FGF20 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## P2RY10 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ITM2A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NRD1 96.74 101.43 98.20 119.49 94.74 99.44 115.61
## VDAC3 77.04 53.03 56.58 75.37 62.50 59.93 69.68
## PCM1 35.99 34.78 34.36 47.22 33.91 27.11 33.86
## TNRC6C 0.29 0.44 0.47 0.57 0.38 0.19 0.51
## CBFA2T2 7.23 8.18 9.08 7.77 8.59 6.89 9.83
## BRINP1 0.00 0.01 0.01 0.00 0.02 0.00 0.00
## ITCH 49.02 77.79 70.35 41.81 57.98 32.10 50.33
## PKD2L2 0.00 0.02 0.01 0.00 0.00 0.00 0.03
## TP53INP2 4.41 4.94 6.29 4.23 4.39 2.97 3.92
## SDF4 94.06 102.35 115.49 106.87 97.86 58.48 103.56
## MYH7B 0.16 0.40 0.16 1.16 0.33 0.76 0.64
## BPIFB2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TP73 1.21 0.77 1.34 0.95 0.53 0.75 0.62
## TOLLIP 27.71 32.45 40.52 23.62 27.96 13.60 33.49
## UBE2D4 4.33 2.99 3.57 8.40 3.08 6.01 5.40
## CLUL1 1.14 0.31 0.89 0.00 0.15 0.00 0.17
## RUNX1T1 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## CDH17 0.00 0.00 0.00 0.00 0.07 0.00 0.00
## THOC1 35.68 38.35 34.04 54.32 37.63 37.69 35.03
## FKBP7 6.41 5.90 5.44 3.67 5.69 3.51 3.66
## OSBPL6 6.31 8.38 9.58 10.53 6.20 5.07 8.06
## SLC1A3 8.79 10.40 9.97 10.52 7.27 8.42 6.33
## XRCC5 123.91 118.49 119.06 154.00 125.99 104.80 126.41
## LXN 4.14 3.28 2.42 7.97 3.51 4.94 3.09
## SP140 0.17 0.39 0.91 0.00 0.53 0.28 0.40
## MKNK1 19.08 16.24 17.40 24.01 19.37 16.00 24.67
## TNS1 0.39 0.39 0.75 2.41 0.26 0.50 0.53
## REXO1 14.44 17.52 20.10 23.41 16.34 14.59 19.81
## SAR1A 83.32 97.78 99.96 66.87 91.85 50.99 79.21
## CDC14A 0.19 0.21 0.17 1.20 0.23 0.16 0.20
## RAPGEF3 5.99 5.32 3.09 6.97 4.55 10.30 4.02
## CEACAM1 2.89 2.08 3.02 0.62 2.37 0.57 1.75
## SENP1 8.99 10.11 10.84 9.85 10.56 5.79 10.36
## DUSP13 0.07 0.12 0.04 0.00 0.41 0.12 0.12
## CIC 15.63 20.41 26.99 29.00 16.86 14.26 21.57
## LIPE 6.75 7.61 7.82 5.57 6.17 4.70 5.46
## FDFT1 132.76 217.47 166.21 171.61 153.86 131.60 153.08
## PAFAH1B3 35.32 25.81 25.66 33.92 25.29 32.86 37.80
## OPHN1 0.91 1.03 1.17 0.86 0.54 0.38 0.75
## AFM 0.00 0.00 0.00 0.00 0.00 0.00 0.52
## KIF22 57.69 46.92 48.75 72.07 51.88 59.29 55.66
## SCGN 0.00 0.02 0.00 0.00 0.00 0.00 0.00
## LRRC16A 7.77 7.66 6.40 3.84 8.45 7.38 7.94
## PGM1 18.55 24.96 27.88 14.55 12.52 13.78 12.60
## DDX1 80.03 91.53 89.84 87.17 80.65 61.63 74.95
## DNM2 60.28 63.52 75.88 71.15 60.63 52.44 67.87
## EPB41L2 15.86 17.01 17.37 17.69 20.05 15.43 18.35
## RIMS1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MOXD1 0.02 0.02 0.07 0.07 0.05 0.02 0.04
## STX7 18.51 22.10 22.04 12.21 19.57 10.51 17.04
## RABL2B 6.23 7.50 6.84 6.94 6.12 8.21 6.80
## KEAP1 69.86 61.83 72.28 85.20 70.49 47.42 75.77
## DDX43 7.58 9.36 9.30 9.28 9.79 4.51 7.46
## PTPRH 2.84 3.05 5.33 1.65 1.93 1.95 2.60
## DCT 0.00 0.00 0.00 0.00 0.00 0.00 0.02
## SLC35C2 56.41 70.70 73.38 52.38 61.40 36.97 60.64
## CRYBG3 8.09 7.68 7.54 12.91 9.87 7.46 8.64
## EPHA6 0.00 0.07 0.11 0.00 0.07 0.00 0.03
## SCTR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RFX3 0.34 0.57 0.70 1.30 0.36 0.51 0.77
## RIF1 6.81 8.10 8.53 13.34 8.74 5.41 7.96
## RAB21 28.62 35.24 40.60 24.98 36.55 15.12 29.57
## SLC4A4 0.00 0.00 0.00 0.00 0.01 0.00 0.07
## SMARCA2 16.13 16.32 21.88 22.23 19.46 8.68 11.57
## RDH8 0.00 0.02 0.05 0.00 0.00 0.00 0.00
## SESN1 10.46 14.51 15.72 9.15 14.19 3.32 10.47
## MID2 2.37 3.13 3.06 2.97 1.90 1.00 2.22
## PIH1D3 0.03 0.00 0.00 0.00 0.00 0.00 0.00
## COL5A3 0.35 0.51 0.48 0.24 0.37 0.10 0.32
## SRCAP 11.29 12.68 16.91 16.32 11.70 11.30 15.22
## KIAA0020 49.68 58.73 45.26 49.77 65.11 48.34 51.21
## CPB2 0.10 0.04 0.00 0.00 0.00 0.00 0.26
## CHRNA3 0.34 0.36 0.71 0.00 0.61 0.47 0.79
## KCNN2 0.07 0.14 0.01 0.00 0.04 0.00 0.00
## CNOT4 5.11 4.79 7.35 6.14 6.05 3.65 6.02
## PSEN1 33.83 35.47 42.79 27.27 41.93 16.49 40.80
## CPOX 10.21 8.89 9.57 13.19 10.65 10.46 10.03
## CLDND1 85.52 104.39 106.03 60.52 101.64 50.47 80.19
## MOK 13.51 16.86 11.70 20.33 13.82 23.52 15.89
## HSP90AA1 342.45 377.14 295.49 640.51 468.63 349.64 421.88
## RBL1 7.16 6.55 8.15 12.88 9.62 8.26 10.08
## DLGAP4 38.81 61.01 57.27 46.16 49.11 24.84 41.72
## IGSF9B 0.08 0.16 0.24 0.39 0.10 0.08 0.09
## CFHR2 0.00 0.00 0.00 0.00 0.00 0.00 0.66
## NDC80 24.71 24.26 23.29 26.04 26.66 16.21 21.00
## AP4E1 4.78 7.46 6.89 6.97 6.19 3.59 5.78
## RSBN1 3.06 3.09 4.03 3.18 3.53 1.95 2.56
## MAGI3 2.10 1.85 2.08 3.16 2.05 1.20 1.63
## CXCL2 8.22 12.68 11.56 6.37 13.71 11.22 13.85
## AFP 0.04 0.00 0.00 0.00 0.00 0.00 0.00
## COL4A4 0.13 0.25 0.17 0.19 0.21 0.11 0.15
## TCF7 1.67 2.57 2.92 1.43 2.48 0.60 1.81
## OSTM1 18.15 20.82 21.97 23.28 25.95 12.47 21.98
## CDH7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## IMPG2 0.01 0.00 0.01 0.00 0.01 0.00 0.04
## PCNP 114.00 145.90 147.11 89.39 144.67 75.02 99.50
## EXD2 8.87 8.78 10.29 9.67 8.77 5.06 8.91
## ARG2 32.75 42.83 41.82 14.72 28.36 13.08 27.37
## MEF2C 0.00 0.00 0.06 0.00 0.02 0.00 0.00
## PTPRC 0.01 0.00 0.00 0.00 0.00 0.00 0.00
## CACNA1S 0.00 0.00 0.01 0.00 0.00 0.00 0.02
## PKP1 159.29 173.74 248.07 107.95 105.80 78.83 90.56
## UBA5 20.92 24.53 24.03 23.75 24.66 21.22 23.95
## STK17B 7.99 9.17 10.74 5.23 8.75 3.05 6.32
## CDC14B 2.84 3.89 2.94 5.27 3.32 3.14 3.63
## ZNF510 5.48 5.45 6.85 5.32 5.75 4.69 6.04
## LRP2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZNF506 2.73 3.52 4.80 1.23 3.22 2.05 2.45
## JMJD4 23.08 22.92 23.97 27.51 19.98 19.27 22.13
## DUSP12 40.08 41.18 41.92 39.75 36.74 34.36 43.38
## AACS 23.19 30.84 33.46 18.75 22.34 16.26 24.32
## KIAA0141 58.43 67.27 62.83 64.25 63.44 48.69 55.15
## SLC13A1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CADPS2 1.01 0.91 1.87 0.00 0.62 0.35 0.61
## PCDHB4 0.01 0.00 0.01 0.00 0.01 0.00 0.00
## PCDHA6 0.02 0.00 0.02 0.00 0.00 0.07 0.00
## PCDHGA2 0.05 0.07 0.09 0.00 0.08 0.00 0.03
## HSPB11 52.56 43.49 40.43 99.04 61.40 103.43 59.55
## PHLPP1 2.16 2.60 2.71 2.77 2.08 1.72 2.73
## ATP8B1 3.91 3.33 4.18 3.49 3.72 1.78 3.28
## IL12RB2 3.19 2.85 3.20 3.95 2.77 3.65 2.40
## SMARCD3 5.86 6.03 7.01 6.76 5.37 5.28 6.28
## WDR70 35.86 27.22 27.23 15.98 32.21 26.45 31.60
## FYB 0.19 0.09 0.30 0.14 0.11 0.00 0.07
## MPP4 0.00 0.05 0.04 0.00 0.06 0.19 0.11
## STRADB 5.25 3.86 5.72 5.98 5.05 3.25 5.97
## BZW1 170.17 180.99 167.29 156.92 214.06 131.07 191.06
## PGR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## C1QTNF3 0.57 0.45 0.68 0.00 0.73 0.37 0.32
## ME2 27.21 34.81 32.06 14.96 26.87 12.42 25.05
## C5orf22 22.93 29.98 35.15 19.08 33.53 13.07 24.59
## CCNT2 8.20 11.30 13.07 13.84 12.22 10.55 11.33
## FAM135A 9.23 13.32 15.35 13.93 13.39 7.46 9.33
## COL19A1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## EPB41L3 0.00 0.07 0.00 0.00 0.00 0.00 0.00
## COBLL1 6.18 7.08 9.76 9.52 7.24 5.62 6.55
## DLG3 6.23 5.64 5.50 4.57 4.46 2.72 3.86
## KCNK2 0.89 0.46 0.46 2.69 0.85 0.61 0.35
## SERTAD4 1.55 1.67 1.95 2.49 2.01 2.36 1.70
## TRAF5 3.72 3.56 3.84 4.45 3.81 3.39 4.03
## MRPL22 168.99 130.38 121.48 176.84 151.85 144.70 153.13
## GEMIN5 11.90 14.50 14.99 22.28 12.65 12.89 12.27
## OPRK1 0.00 0.00 0.01 0.00 0.00 0.00 0.02
## NFE2L1 60.83 76.66 97.37 54.45 67.26 31.97 71.61
## SEMA5B 0.18 0.19 0.35 0.00 0.06 0.00 0.13
## GSK3B 41.99 55.53 48.76 34.40 46.23 19.35 37.61
## ITGB5 30.72 29.36 35.72 57.08 25.79 27.70 34.30
## ERC1 3.57 4.04 5.27 4.69 3.73 2.73 4.13
## XPO1 64.35 61.40 66.24 85.70 71.84 67.91 67.43
## C4orf6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RNF13 40.38 39.16 44.04 30.76 36.92 21.96 32.13
## TRPM3 0.01 0.00 0.00 0.00 0.00 0.01 0.01
## PALB2 24.83 28.73 30.35 25.42 31.65 12.90 20.07
## DOPEY1 1.70 1.41 1.80 2.25 1.15 1.58 1.51
## LYRM2 22.83 23.37 19.59 28.34 22.71 19.71 25.62
## BCKDHB 4.00 4.74 4.10 3.38 3.74 3.07 3.89
## mRNA_R45 mRNA_R49 mRNA_R48 mRNA_R47 mRNA_R46 mRNA_R44 mRNA_R43
## TSPAN6 10.35 9.95 6.47 9.83 5.07 11.59 2.96
## TNMD 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DPM1 124.89 152.52 97.52 148.47 61.81 132.04 14.48
## SCYL3 5.14 4.29 2.12 5.34 1.28 8.40 0.45
## C1orf112 14.63 11.95 9.32 10.10 9.42 9.22 6.05
## FGR 0.01 0.01 0.09 0.02 0.00 0.03 0.00
## CFH 0.29 0.49 0.33 0.58 0.20 0.69 0.12
## FUCA2 22.39 20.74 15.86 18.00 12.19 18.00 6.29
## GCLC 11.73 12.28 5.50 13.78 2.93 26.52 0.65
## NFYA 6.84 9.04 4.05 6.21 2.82 10.19 1.61
## STPG1 7.18 5.95 4.21 6.02 4.55 10.25 4.26
## NIPAL3 13.04 13.23 9.47 11.59 8.69 15.75 5.38
## LAS1L 53.57 43.83 42.51 47.75 39.18 46.13 35.35
## ENPP4 0.56 0.50 0.17 0.67 0.11 1.10 0.04
## SEMA3F 1.47 1.65 1.83 1.44 1.59 2.28 1.06
## CFTR 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## ANKIB1 9.21 8.81 3.25 8.12 2.20 13.84 0.40
## CYP51A1 25.63 16.73 10.83 19.14 7.26 23.39 4.62
## KRIT1 14.49 12.10 7.24 12.28 3.90 18.69 1.68
## RAD52 4.73 5.12 3.08 5.41 1.30 6.59 1.63
## BAD 35.08 59.05 54.43 30.86 72.54 19.00 62.40
## LAP3 38.60 41.57 25.13 49.72 20.92 57.27 7.75
## CD99 19.38 25.22 22.88 24.11 22.79 23.70 15.84
## HS3ST1 0.44 0.62 0.16 0.28 0.07 0.16 0.03
## AOC1 0.02 0.01 0.00 0.00 0.00 0.00 0.05
## WNT16 0.25 0.25 0.30 0.27 0.13 0.20 0.07
## HECW1 2.03 2.96 3.80 3.25 3.18 2.27 2.99
## MAD1L1 20.85 19.89 29.55 17.35 39.58 18.88 51.33
## LASP1 39.71 28.76 20.39 36.15 16.33 52.65 8.82
## SNX11 11.78 10.66 8.52 13.43 8.79 20.21 5.27
## TMEM176A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## M6PR 106.88 117.79 80.57 117.79 70.22 163.92 41.80
## KLHL13 1.05 1.51 0.43 1.08 0.28 1.06 0.03
## CYP26B1 0.22 0.23 0.14 0.10 0.09 0.16 0.03
## ICA1 10.80 9.93 8.55 14.16 5.93 13.41 3.07
## DBNDD1 14.86 23.80 13.26 10.10 14.47 9.31 8.00
## ALS2 5.53 5.44 2.17 6.57 1.25 8.47 0.63
## CASP10 0.44 0.50 0.49 0.55 0.45 1.05 0.46
## CFLAR 6.82 5.63 4.43 6.28 4.58 7.92 2.58
## TFPI 0.87 1.04 0.52 0.83 0.43 1.08 0.30
## NDUFAF7 15.37 17.35 13.22 19.67 14.24 21.25 12.92
## RBM5 30.39 25.55 18.96 31.47 14.13 48.72 8.67
## MTMR7 0.32 0.61 0.48 0.58 0.58 0.52 0.46
## SLC7A2 1.92 2.03 1.31 1.55 0.94 1.72 0.50
## ARF5 108.86 133.77 119.75 119.75 103.24 118.36 66.30
## SARM1 9.99 10.63 7.38 9.14 6.75 8.65 5.27
## POLDIP2 102.22 102.13 83.59 102.85 76.87 119.53 51.94
## PLXND1 18.44 17.68 14.22 8.63 25.33 6.68 27.19
## AK2 216.83 189.77 158.39 176.61 151.32 201.82 121.21
## CD38 0.00 0.11 0.00 0.07 0.00 0.06 0.00
## FKBP4 119.49 127.87 106.75 93.86 111.31 109.08 99.70
## KDM1A 55.28 69.01 47.78 41.50 39.27 42.31 30.39
## RBM6 35.72 40.78 44.57 36.82 47.10 38.89 49.29
## CAMKK1 2.35 2.40 1.94 1.38 1.68 1.25 1.61
## RECQL 46.73 29.17 14.50 37.98 8.85 57.70 4.85
## CCDC132 6.78 4.96 3.53 5.43 1.48 8.31 0.50
## HSPB6 0.41 0.50 0.42 0.15 0.46 0.34 0.34
## ARHGAP33 1.75 1.65 1.42 2.65 1.76 4.18 1.20
## NDUFAB1 230.02 281.81 317.18 265.42 335.75 229.37 363.65
## PDK4 2.77 6.41 2.11 2.84 0.88 2.23 0.35
## SLC22A16 0.00 0.04 0.02 0.02 0.14 0.08 0.00
## ZMYND10 0.71 1.19 1.02 0.84 1.94 0.66 2.09
## ABCB5 0.01 0.00 0.00 0.00 0.00 0.00 0.00
## ARX 0.02 0.06 0.02 0.04 0.00 0.02 0.01
## SLC25A13 20.36 19.34 11.70 16.11 7.88 22.72 4.38
## ST7 13.01 13.63 10.38 12.14 8.94 16.04 6.41
## CDC27 21.28 21.19 14.71 15.94 11.74 27.51 5.08
## SLC4A1 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## CALCR 0.00 0.00 0.00 0.01 0.00 0.00 0.00
## HCCS 57.99 55.75 46.92 48.02 37.12 60.98 29.48
## DVL2 32.20 29.68 20.73 25.33 16.87 35.90 14.22
## PRSS22 0.00 0.00 0.00 0.00 0.00 0.04 0.00
## UPF1 40.05 37.35 29.53 32.85 24.63 40.70 14.84
## SKAP2 9.44 8.10 3.98 11.12 1.90 14.48 0.46
## SLC25A5 639.68 606.37 534.41 562.88 438.64 452.13 195.62
## CCDC109B 14.32 15.94 10.42 13.14 8.37 12.65 6.19
## HOXA11 0.86 0.54 0.95 0.53 0.59 0.40 0.16
## POLR2J 135.23 175.39 163.25 131.48 176.30 109.01 166.27
## DHX33 9.09 8.75 4.54 7.82 4.24 12.33 3.27
## MEOX1 0.00 0.00 0.02 0.00 0.00 0.05 0.04
## THSD7A 0.18 0.07 0.03 0.10 0.02 0.07 0.00
## LIG3 10.27 7.30 5.75 5.90 3.93 8.73 2.68
## RPAP3 25.07 33.48 20.63 22.96 14.19 25.55 8.10
## ACSM3 2.32 2.44 2.24 3.14 1.17 1.34 1.08
## AC004381.6 10.80 7.43 6.43 8.49 5.74 6.97 3.32
## CIAPIN1 57.64 56.28 45.70 61.82 44.58 75.77 27.68
## FAM214B 8.31 9.08 7.31 11.90 7.76 20.26 8.65
## COPZ2 33.28 37.75 45.86 34.43 52.29 21.82 58.27
## PRKAR2B 5.15 7.40 2.07 5.27 1.11 6.40 0.28
## MSL3 12.95 12.63 8.58 12.89 6.42 17.12 3.27
## CREBBP 6.59 7.13 7.00 5.62 5.39 9.12 4.87
## BZRAP1 0.00 0.10 0.00 0.00 0.00 0.02 0.00
## MPO 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PON1 0.03 0.05 0.00 0.00 0.05 0.00 0.01
## GCFC2 31.10 24.17 25.58 24.39 26.82 22.12 27.78
## WDR54 51.47 65.06 75.96 48.58 94.04 28.88 138.93
## CROT 6.00 5.53 3.70 8.46 2.60 8.89 1.19
## ABCB4 4.88 7.63 6.75 3.28 6.28 0.80 7.02
## KMT2E 6.16 5.14 2.69 5.21 1.49 9.41 0.92
## RHBDD2 34.52 40.49 36.49 45.59 45.32 66.36 43.62
## SOX8 0.54 0.52 0.51 0.52 0.41 0.45 0.34
## IBTK 10.90 15.38 9.62 13.78 7.70 12.59 6.67
## ZNF195 10.67 10.23 5.83 13.94 4.30 19.82 2.57
## MYCBP2 4.75 4.45 2.15 3.97 1.35 5.50 0.24
## FBXL3 13.52 12.55 5.50 13.49 2.83 18.67 1.20
## ITGAL 0.04 0.00 0.00 0.00 0.00 0.01 0.00
## PDK2 8.45 10.89 8.10 7.47 7.47 7.50 4.68
## ITGA3 61.39 50.04 39.07 37.80 52.11 48.44 43.75
## ZFX 5.00 5.67 2.37 4.60 1.66 8.22 0.94
## LAMP2 32.79 28.96 11.44 35.23 6.36 69.60 2.40
## GGNBP2 43.88 40.48 34.94 42.75 25.46 52.27 14.80
## ITGA2B 0.12 0.37 0.49 0.00 0.12 0.17 0.14
## ASB4 0.00 0.00 0.10 0.00 0.00 0.00 0.01
## GDE1 22.30 26.58 18.04 25.45 16.16 33.96 9.03
## C19orf60 90.14 114.92 148.35 100.24 189.60 79.91 260.70
## CRLF1 17.33 24.21 21.96 18.59 28.82 16.92 24.44
## OSBPL7 6.89 6.64 5.23 6.87 4.33 6.69 4.54
## TMEM98 38.16 30.61 25.62 29.71 22.78 28.78 12.16
## YBX2 0.06 0.03 0.01 0.02 0.08 0.05 0.03
## KRT33A 0.00 0.00 0.00 0.00 0.00 0.02 0.00
## ABCC8 0.04 0.00 0.00 0.00 0.00 0.21 0.00
## CCL18 0.00 0.00 0.04 0.00 0.00 0.02 0.00
## CCL3 0.04 0.07 0.03 0.04 0.00 0.04 0.00
## SYNRG 7.42 6.37 3.89 6.97 2.66 11.98 1.53
## CACNG3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMEM132A 29.52 38.71 36.45 25.39 45.95 22.70 51.52
## AP2B1 45.22 36.97 28.20 39.82 23.45 60.98 17.42
## TAC1 28.26 58.95 30.92 34.60 19.54 61.61 8.99
## ZNF263 25.65 22.84 15.56 26.69 13.51 34.67 12.70
## CX3CL1 1.05 0.51 0.49 0.71 0.40 1.01 0.31
## SPATA20 27.73 24.19 19.39 26.81 15.52 28.39 9.55
## CACNA1G 0.01 0.01 0.02 0.01 0.02 0.04 0.01
## TNFRSF12A 272.03 149.15 131.23 245.74 152.53 300.44 82.28
## DLX6 0.43 0.37 0.32 0.32 0.16 0.29 0.11
## MAP3K9 0.67 0.69 0.35 0.47 0.41 0.72 0.24
## RALA 39.10 38.10 35.21 34.48 34.93 42.53 36.19
## BAIAP2L1 13.30 7.84 5.61 11.27 6.05 12.50 3.47
## KDM7A 1.39 1.22 0.70 2.13 0.39 3.48 0.13
## ETV1 10.47 13.67 5.61 10.41 3.83 12.98 2.02
## AGK 23.59 15.26 9.76 18.29 5.20 28.83 2.14
## ALDH3B1 3.98 4.31 3.49 3.70 2.72 3.35 1.99
## TTC22 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PHTF2 7.06 7.62 3.16 6.13 1.79 6.97 0.62
## CCL26 0.12 0.06 0.00 0.18 0.05 0.07 0.00
## FARP2 11.84 9.74 6.96 9.73 4.70 23.26 3.65
## USH1C 0.00 0.00 0.00 0.00 0.00 0.00 0.02
## GGCT 134.54 122.97 113.95 134.72 101.70 106.11 79.13
## DBF4 16.33 22.12 9.03 15.09 5.66 15.86 1.35
## TBXA2R 0.76 0.84 0.81 0.71 0.94 0.98 0.63
## IFRD1 26.30 16.86 12.77 32.48 8.56 64.87 7.38
## LGALS14 0.00 0.00 0.00 0.00 0.00 0.16 0.00
## COX10 10.29 9.30 6.19 11.29 4.80 17.22 3.67
## GTF2IRD1 19.71 21.28 18.21 23.36 16.57 20.96 8.09
## PAF1 34.13 46.14 36.65 31.08 38.00 27.40 31.81
## VPS41 14.88 11.68 6.88 17.45 4.29 30.49 2.90
## ARHGAP44 0.74 0.66 0.55 0.60 0.41 0.71 0.39
## ELAC2 33.95 40.24 29.26 30.24 30.87 31.69 20.93
## SCIN 0.11 0.22 0.14 0.09 0.03 0.04 0.02
## ARSD 11.45 10.36 10.95 15.02 9.89 16.54 10.57
## PNPLA4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MYH13 0.19 0.13 0.14 0.19 0.07 0.18 0.07
## ADIPOR2 24.17 22.67 15.09 22.05 11.21 34.05 5.84
## CDKL3 2.01 1.45 1.63 2.40 1.60 5.12 1.03
## UPP2 0.00 0.00 0.00 0.00 0.00 0.01 0.05
## PRSS21 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MARK4 11.50 10.14 6.79 10.98 5.84 16.36 4.08
## PROM1 0.07 0.05 0.04 0.11 0.07 0.15 0.10
## CCDC124 132.92 149.97 144.46 115.82 163.51 108.50 144.08
## CEACAM21 0.00 0.01 0.00 0.01 0.00 0.05 0.00
## PAFAH1B1 57.63 67.13 56.05 55.61 57.03 71.27 46.67
## NOS2 0.01 0.00 0.01 0.00 0.00 0.01 0.00
## DNAH9 1.81 2.44 1.28 2.08 1.34 3.35 0.95
## KIAA0100 25.76 25.51 16.68 18.77 13.20 27.28 9.27
## SLC13A2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GAS7 39.56 42.85 27.21 26.99 26.02 32.27 22.87
## TRAPPC6A 3.39 6.11 6.34 2.38 6.96 2.11 9.09
## MATK 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CEACAM7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CD79B 0.02 0.06 0.09 0.15 0.06 0.00 0.00
## SCN4A 0.00 0.01 0.00 0.00 0.00 0.01 0.00
## ST7L 11.07 10.89 11.76 10.63 9.52 9.95 8.62
## TKTL1 0.16 0.32 0.11 0.08 0.11 0.10 0.05
## PAX6 0.21 0.35 0.16 0.25 0.12 0.34 0.05
## RPUSD1 30.94 40.81 30.30 27.65 33.30 27.83 25.80
## RHBDF1 36.55 32.94 26.21 36.26 26.15 37.31 12.28
## LUC7L 27.11 40.80 32.16 28.07 35.31 25.47 25.76
## CACNA2D2 0.10 0.09 0.05 0.07 0.09 0.06 0.02
## BAIAP3 0.88 0.42 0.36 0.56 0.33 1.51 0.32
## TSR3 65.30 62.14 73.61 59.93 91.19 57.47 101.16
## PIGQ 20.80 24.31 22.88 18.91 26.50 14.68 29.90
## CRAMP1L 7.92 6.05 3.56 6.88 2.56 9.65 0.96
## TEAD3 5.17 4.19 2.73 4.70 1.93 5.98 0.93
## SELE 0.15 0.07 0.04 0.00 0.03 0.00 0.01
## DNAJC11 30.60 34.84 23.59 29.53 23.67 37.13 24.35
## FMO3 0.01 0.08 0.11 0.05 0.00 0.00 0.00
## MYLIP 7.37 9.97 6.60 5.99 2.92 5.54 1.16
## NOX1 0.19 0.30 0.33 0.50 0.37 0.37 0.15
## E2F2 6.37 4.70 3.57 3.22 4.19 1.66 2.88
## PSMB1 257.18 314.16 325.97 278.99 351.62 244.77 355.01
## SYN1 0.11 0.14 0.15 0.10 0.05 0.17 0.10
## JARID2 7.69 5.95 3.73 6.65 2.85 8.09 2.04
## CDKL5 0.09 0.08 0.01 0.11 0.02 0.18 0.01
## CAMK1G 0.05 0.05 0.00 0.00 0.00 0.00 0.00
## CDK11A 26.35 30.94 19.45 33.47 15.53 48.10 10.57
## NADK 24.15 27.07 18.58 21.32 16.96 27.54 12.54
## TFAP2B 47.50 104.49 62.99 49.40 43.91 25.50 27.36
## TFAP2D 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DLEC1 0.15 0.04 0.08 0.23 0.14 0.16 0.02
## CYTH3 6.92 4.74 2.66 5.94 1.81 8.49 1.21
## ADAM22 1.73 1.81 1.11 1.22 0.89 1.79 0.40
## SYPL1 43.58 51.61 24.58 50.24 21.71 55.29 10.99
## CYB561 21.62 22.78 17.02 18.76 16.42 19.83 13.70
## SPAG9 23.10 21.20 10.25 24.94 6.12 44.52 3.21
## CELSR3 2.56 2.61 1.84 2.41 1.38 2.65 0.74
## AASS 4.81 3.55 2.36 2.77 1.52 5.77 0.64
## PLEKHG6 0.28 0.25 0.05 0.24 0.10 0.45 0.13
## SS18L2 37.65 43.66 47.13 38.31 49.61 28.21 44.75
## MPND 10.86 14.00 16.85 7.20 19.18 5.49 30.47
## MGST1 89.38 63.56 45.36 97.38 33.21 96.24 10.03
## CRY1 6.84 13.01 4.04 4.42 1.82 4.92 0.37
## PGLYRP1 0.00 0.00 0.00 0.00 0.04 0.18 0.00
## NFIX 35.13 31.68 19.40 25.22 17.77 37.86 18.83
## ST3GAL1 8.88 6.20 3.80 7.18 3.53 10.34 2.54
## MMP25 0.47 0.53 0.39 0.60 0.38 1.33 0.43
## IL32 10.05 4.29 5.67 3.79 4.93 3.78 5.80
## PKD1 29.77 21.37 11.58 32.40 6.69 60.13 5.25
## MAPK8IP2 0.13 0.10 0.06 0.09 0.05 0.22 0.10
## MED24 36.39 34.50 28.51 25.70 23.80 30.83 14.42
## RHOBTB2 7.02 7.44 5.03 7.84 4.83 9.44 3.01
## HEATR5B 3.56 2.82 1.67 3.51 1.03 6.23 0.50
## SEC62 40.04 56.99 41.55 47.01 49.43 47.35 101.73
## RPS20 4067.62 3811.57 4883.42 3881.70 5034.52 3068.99 5941.54
## CSDE1 155.54 154.25 85.55 124.53 62.16 156.22 41.65
## UBE3C 26.80 22.58 12.68 21.09 9.39 33.92 5.41
## REV3L 5.11 4.69 2.84 4.92 1.51 5.80 0.31
## TENM1 0.30 0.33 0.15 0.17 0.09 0.23 0.12
## PAX7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MASP2 0.51 0.35 0.11 0.49 0.04 0.83 0.08
## IYD 0.00 0.00 0.00 0.01 0.00 0.00 0.00
## FAM76A 3.52 2.96 1.57 3.23 1.23 3.94 0.99
## TRAF3IP3 3.05 2.79 1.71 3.64 1.73 3.38 1.05
## POMT2 4.67 6.82 7.10 6.15 7.27 6.79 7.10
## VTA1 29.48 29.17 15.28 28.60 9.59 38.67 5.42
## MLXIPL 0.36 0.25 0.27 0.43 0.21 0.47 0.23
## BAZ1B 23.63 21.57 12.35 19.04 9.88 26.69 5.85
## RANBP9 12.70 14.73 5.82 11.26 3.40 17.29 0.83
## ETV7 0.13 0.02 0.09 0.02 0.12 0.00 0.08
## SPRTN 7.77 7.60 3.76 6.74 3.57 11.36 1.59
## METTL13 38.81 54.47 45.86 49.80 48.19 49.34 35.59
## DYRK4 31.46 36.86 37.10 27.46 35.42 26.05 27.22
## ZNF207 129.13 129.22 76.04 114.92 50.96 149.65 25.34
## UQCRC1 111.49 137.17 123.15 100.97 152.11 83.30 134.33
## STARD3NL 29.67 30.45 18.46 26.75 10.82 27.74 4.74
## CD9 133.90 144.82 94.13 149.55 55.35 145.20 16.06
## HHATL 0.00 0.00 0.00 0.00 0.07 0.00 0.00
## NCAPD2 27.12 28.29 17.68 19.99 13.11 24.71 5.36
## IFFO1 12.74 16.28 13.94 13.53 12.23 13.03 9.16
## GIPR 0.37 0.30 0.35 0.12 0.19 0.18 0.15
## PHF7 8.67 6.29 2.75 7.16 1.78 8.92 0.73
## SEMA3G 0.51 0.78 0.50 0.34 0.45 0.34 0.22
## NISCH 19.39 16.40 13.11 20.83 11.32 35.97 8.96
## STAB1 0.03 0.04 0.04 0.14 0.01 0.08 0.00
## FUZ 43.55 54.46 51.61 30.59 44.30 22.91 39.05
## SLC6A13 0.07 0.14 0.06 0.37 0.05 0.64 0.02
## IDS 31.75 30.97 20.14 28.81 19.21 44.82 13.09
## PRSS3 2.14 0.77 1.66 2.22 2.05 2.65 1.97
## ZNF200 12.45 7.76 5.17 9.19 3.45 13.58 1.92
## CD4 0.39 0.44 0.29 0.31 0.27 0.24 0.13
## LRRC23 18.37 18.51 21.77 20.29 23.15 15.40 36.89
## BTK 0.01 0.08 0.00 0.01 0.00 0.01 0.00
## HFE 2.25 2.88 2.07 2.79 0.80 3.07 0.20
## SCMH1 15.50 12.35 10.10 10.58 11.21 12.10 8.19
## FYN 16.88 21.08 11.67 18.82 9.26 29.38 3.68
## HIVEP2 2.04 1.56 0.96 1.47 0.70 1.66 0.36
## FMO1 0.05 0.00 0.09 0.03 0.01 0.00 0.00
## TCEB3 41.46 40.06 25.14 37.73 18.47 51.36 10.14
## LYPLA2 103.72 142.12 120.49 114.24 129.97 109.24 118.20
## CLCN6 2.14 2.11 1.30 2.31 1.05 4.95 0.53
## MRC2 15.55 22.64 17.09 14.35 15.65 13.02 11.44
## NME2 413.00 461.77 570.11 419.02 703.02 347.03 1225.67
## SLC6A7 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## TSPAN9 6.46 5.10 3.97 7.82 3.90 10.77 3.27
## BTBD7 3.10 3.31 1.75 3.12 1.55 4.28 0.71
## APBA3 10.09 8.53 7.57 9.29 5.88 11.86 4.41
## MKS1 11.04 8.86 7.97 9.59 7.32 10.32 4.04
## ABHD5 7.50 6.31 4.57 6.93 3.61 14.11 1.57
## KAL1 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## AKAP8L 34.93 39.41 34.24 41.75 32.24 55.39 42.74
## MBTD1 3.46 3.09 1.09 3.04 0.63 4.80 0.14
## UTP18 43.97 51.79 46.98 40.40 47.95 38.72 64.71
## RNF216 11.84 12.09 7.91 11.26 6.52 14.29 3.48
## TTC19 41.75 39.66 31.66 41.60 24.70 44.13 18.50
## PTBP1 139.43 130.26 102.40 107.73 102.58 155.03 92.08
## DPF1 7.10 9.89 7.00 6.68 7.67 5.83 6.86
## SYT7 0.21 0.07 0.03 0.15 0.06 0.48 0.04
## LARS2 6.77 6.19 4.66 6.62 2.67 8.70 1.42
## PIK3C2A 3.83 2.70 1.44 2.92 0.60 8.18 0.07
## PLAUR 36.29 23.21 20.24 27.01 22.74 25.25 12.61
## ANLN 16.61 23.49 9.27 9.75 4.43 6.94 1.35
## WIZ 21.46 18.81 10.26 14.97 7.84 22.13 4.07
## RABGAP1 7.06 5.65 3.56 6.62 2.83 11.11 1.77
## DCN 0.04 0.08 0.00 0.00 0.00 0.01 0.00
## QPCTL 11.02 12.05 12.33 7.77 11.90 7.91 13.35
## PPP5C 48.75 59.60 34.84 47.82 27.08 45.19 11.70
## CEP68 6.68 4.56 4.28 5.40 3.82 7.98 2.89
## MAP4K3 4.54 5.47 1.38 6.11 0.47 7.71 0.20
## ZBTB32 1.11 0.52 0.35 0.68 0.18 0.82 0.19
## TYROBP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMEM159 4.29 2.57 2.50 6.04 1.93 11.98 1.16
## GABRA3 2.84 4.65 2.83 2.94 2.17 3.84 1.29
## BRCA1 19.11 13.92 8.97 14.76 7.10 13.12 5.11
## ERCC1 148.18 124.68 140.87 94.63 173.20 100.89 241.56
## CD22 1.52 1.48 0.92 1.52 0.44 2.58 0.51
## MBTPS2 14.60 10.97 5.50 15.12 3.01 22.35 1.21
## PRICKLE3 5.09 5.03 2.57 4.92 1.92 6.15 1.46
## LTF 0.01 0.00 0.06 0.00 0.00 0.02 0.00
## EXTL3 7.41 6.19 4.63 5.86 4.14 10.22 3.39
## NR1H4 0.02 0.01 0.00 0.00 0.00 0.00 0.00
## ELOVL5 38.96 39.63 25.08 38.07 18.99 46.72 13.76
## ALOX5 0.00 0.06 0.00 0.00 0.00 0.00 0.00
## KDM5D 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CALCOCO1 18.16 16.06 14.18 17.82 9.70 21.67 6.72
## UBR7 23.24 23.95 12.75 20.87 10.01 21.20 16.30
## MAP4K5 6.80 6.97 2.83 6.50 1.62 9.39 0.70
## EHD3 7.86 11.44 6.54 8.08 4.79 12.72 2.50
## PSMC4 161.44 223.34 179.24 178.51 184.67 191.25 119.22
## MAN2B2 8.07 6.62 4.99 8.35 4.83 11.14 3.96
## SLC7A14 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## CLDN11 0.07 0.04 0.05 0.02 0.02 0.12 0.03
## SLC25A39 83.18 91.05 73.39 70.79 68.96 69.74 46.96
## MVP 34.28 51.26 43.78 42.53 40.21 40.17 32.56
## NUB1 47.22 44.61 23.21 42.52 17.80 54.57 15.75
## PGM3 11.79 6.46 6.12 10.22 4.51 21.82 2.44
## RWDD2A 4.48 3.91 3.63 6.07 2.84 8.01 1.88
## CLK1 21.97 24.45 18.51 28.51 17.31 36.22 8.22
## POLR3B 6.41 5.72 4.18 6.64 3.13 8.20 2.14
## ANGEL1 4.42 3.35 2.23 3.42 1.68 4.62 1.25
## RNF14 25.23 21.06 11.66 28.53 9.12 44.41 6.20
## DNASE1L1 14.30 14.11 11.00 11.75 6.94 10.39 3.04
## DDX11 38.28 26.89 19.98 37.55 19.85 38.30 19.53
## HEBP1 21.74 19.81 18.10 24.73 15.87 26.19 7.93
## GPRC5A 32.01 26.43 15.23 23.78 11.26 41.84 6.59
## MAMLD1 1.45 1.39 0.91 1.63 0.96 1.65 0.71
## CD6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TACC3 36.02 46.52 42.18 26.85 51.17 21.59 46.26
## UFL1 3.77 2.61 1.06 3.65 0.58 5.76 0.22
## POLA2 52.54 46.04 42.06 35.69 54.21 25.71 58.51
## ZC3H3 8.15 7.00 4.84 6.80 4.07 10.28 2.90
## CAPN1 29.41 35.76 24.71 26.02 27.10 27.96 18.39
## ACPP 0.44 0.56 0.32 0.25 0.26 0.13 0.35
## MDH1 175.51 206.64 175.46 194.33 134.87 172.85 49.93
## SLC30A9 29.87 37.39 17.87 34.43 12.58 44.42 10.00
## MTMR11 2.37 2.24 1.05 2.45 1.03 5.29 0.46
## COX15 30.02 23.73 18.10 27.72 13.15 37.88 11.45
## CCDC88C 0.37 0.48 0.30 0.36 0.28 0.18 0.39
## YAF2 8.53 9.01 5.41 8.45 2.42 11.54 1.63
## ZMYND11 12.52 14.33 6.14 13.38 3.81 19.17 1.49
## WAS 0.15 0.02 0.07 0.12 0.21 0.20 0.04
## DPEP1 0.00 0.01 0.00 0.00 0.00 0.07 0.00
## BID 24.99 25.37 24.68 22.30 21.39 22.10 9.84
## MATR3 223.21 251.05 111.78 221.70 60.30 212.96 23.53
## NPC1L1 0.00 0.01 0.01 0.02 0.00 0.08 0.00
## XYLT2 13.00 13.09 12.47 13.12 11.16 14.26 12.77
## RGPD5 1.60 1.24 0.92 1.93 0.50 2.48 0.11
## STMN4 0.00 0.02 0.00 0.02 0.00 0.02 0.00
## NUDCD3 24.72 24.86 20.78 26.06 31.45 31.46 39.00
## ISL1 2.54 3.29 2.62 2.09 1.51 1.65 1.07
## CHDH 0.06 0.02 0.01 0.00 0.00 0.07 0.01
## IL20RA 0.00 0.01 0.00 0.04 0.00 0.00 0.00
## CLCA1 0.01 0.01 0.01 0.00 0.01 0.02 0.00
## CLCA4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GLT8D1 57.20 68.02 55.69 56.33 38.05 44.73 19.64
## ATP2C1 27.27 22.21 15.96 30.75 7.80 47.09 2.50
## SRCIN1 1.73 2.06 1.14 1.16 1.43 2.08 1.39
## IGF1 0.00 0.00 0.00 0.01 0.00 0.00 0.00
## SLC38A5 0.08 0.09 0.12 0.10 0.09 0.38 0.19
## MAGIX 0.94 1.31 1.05 0.90 1.37 1.11 0.75
## RALBP1 12.34 11.27 6.89 9.64 5.73 13.46 7.28
## RUFY3 3.78 2.23 2.19 2.90 2.31 6.41 0.91
## CNTN1 0.25 0.59 0.26 0.36 0.05 0.30 0.03
## SLC11A1 0.08 0.07 0.09 0.28 0.09 0.06 0.08
## WWTR1 166.89 199.43 96.90 152.00 69.15 180.83 35.76
## AGPS 7.64 7.30 3.90 6.39 2.98 8.57 2.20
## CXorf56 27.08 28.41 21.21 30.75 15.62 32.14 5.76
## ATP1A2 0.01 0.02 0.00 0.01 0.00 0.00 0.00
## TTC27 16.83 12.90 11.93 11.16 9.22 9.32 6.85
## ZNF582 3.50 4.20 3.65 3.72 3.76 4.69 2.99
## VSIG2 0.90 0.86 0.54 0.44 0.32 0.41 0.37
## PHLDB1 23.67 19.43 15.09 16.80 16.30 17.60 7.92
## MARCO 0.00 0.05 0.00 0.00 0.00 0.00 0.00
## CYP24A1 0.00 0.14 0.00 0.00 0.00 0.00 0.00
## PRDM11 1.90 1.14 0.71 1.31 0.39 2.09 0.31
## SYT13 0.00 0.02 0.00 0.01 0.00 0.02 0.00
## SNAI2 2.83 8.19 4.11 5.86 2.02 5.66 0.47
## CD74 461.29 482.63 428.52 350.09 379.72 313.80 244.09
## HGF 0.15 0.11 0.13 0.04 0.04 0.02 0.00
## ZRANB1 7.65 8.99 4.45 7.20 2.96 8.20 1.50
## NCDN 22.82 23.30 14.65 25.46 10.65 39.09 6.35
## GPR124 1.42 1.21 0.67 1.01 0.65 1.41 0.17
## ZFP64 12.65 11.14 7.06 13.60 5.07 19.46 2.82
## MNAT1 36.59 37.18 30.70 37.92 20.56 37.13 10.92
## SAMD4A 1.51 1.42 0.99 1.25 1.39 1.89 0.99
## RUNX3 7.54 13.06 6.99 3.54 6.69 3.36 4.53
## MRE11A 17.88 12.04 7.78 11.65 4.04 14.57 1.10
## PLEKHB1 1.61 3.15 2.81 1.41 3.54 2.15 4.37
## SERPINB1 13.08 14.41 9.58 8.14 7.33 7.57 4.05
## CYP3A43 0.00 0.00 0.02 0.00 0.00 0.05 0.00
## SLC7A9 0.07 0.15 0.07 0.18 0.02 0.15 0.07
## SPAST 4.03 5.38 1.88 5.53 0.95 7.06 0.37
## NRXN3 0.17 0.12 0.04 0.15 0.07 0.13 0.05
## OSBPL5 4.95 5.73 4.40 4.70 3.66 7.74 3.32
## AQR 16.69 16.56 11.28 18.36 6.70 19.11 2.49
## CPS1 2.90 2.84 1.78 2.37 0.99 3.98 0.52
## C8B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## FHL1 5.22 7.32 4.25 3.83 2.84 3.93 1.49
## RTFDC1 126.92 115.87 96.01 125.07 79.47 155.06 49.72
## GABRA1 0.00 0.01 0.02 0.01 0.01 0.01 0.02
## NLRP2 0.24 0.20 0.30 0.40 0.09 0.22 0.15
## SLC45A4 3.37 2.50 1.83 3.68 1.58 6.88 1.09
## RNF10 61.54 63.50 64.33 59.61 58.37 69.02 48.21
## ZNF839 6.18 6.40 6.37 8.56 5.07 8.99 2.98
## ZDHHC6 16.95 17.78 11.89 17.36 7.82 19.43 4.04
## GRAMD1B 4.15 13.42 7.66 5.18 4.90 5.26 2.15
## RNH1 87.42 96.11 84.44 86.85 79.11 89.68 47.02
## NDUFS1 30.51 25.34 17.03 25.45 9.60 32.16 2.85
## RB1CC1 8.73 7.81 3.47 7.93 1.60 15.07 0.62
## ERP44 21.87 22.04 18.60 24.57 12.94 28.96 10.15
## ALAS1 32.96 28.03 25.43 28.17 24.78 33.84 13.51
## BIRC3 10.26 3.74 3.27 5.57 1.47 6.25 1.66
## AKAP11 5.04 4.44 1.45 4.60 0.65 7.20 0.16
## GLRX2 48.06 59.36 43.78 80.05 36.20 89.45 13.96
## SNAPC1 19.69 11.00 6.97 12.17 4.58 13.37 2.84
## DERA 26.25 23.63 16.86 25.09 12.33 30.19 6.81
## STRAP 197.60 226.72 161.25 227.40 136.09 248.08 67.85
## ABCC2 0.43 0.72 0.25 0.67 0.21 1.84 0.07
## DEF6 0.17 0.20 0.33 0.20 0.14 0.14 0.16
## PLEKHO1 16.37 24.25 23.37 11.20 26.84 10.93 22.13
## GCLM 11.85 11.00 4.30 21.15 2.18 41.12 0.34
## UBR2 2.27 2.57 1.59 2.55 0.96 3.97 0.54
## EHD2 14.78 14.94 10.75 9.02 10.46 9.60 11.09
## DEPDC1 4.19 4.45 2.30 3.11 1.65 2.98 0.45
## CCDC28A 10.13 9.78 9.45 12.04 7.36 10.11 4.23
## RRAGD 10.23 10.52 7.40 9.84 4.38 12.81 2.63
## HSF2 10.59 10.53 5.47 8.82 3.55 8.22 1.48
## PHF20 6.18 6.42 3.48 5.60 3.07 7.58 1.82
## HSD17B6 0.59 0.73 0.62 0.35 0.65 0.18 0.04
## NR1H3 6.99 6.04 7.24 7.27 9.41 6.83 11.30
## TYMP 0.88 1.16 1.76 0.93 2.40 0.48 4.00
## NCAPH2 35.17 33.75 35.91 26.63 48.97 22.86 61.84
## TOMM34 81.36 67.72 50.16 77.64 41.25 85.84 21.75
## SEC63 27.10 27.00 16.02 36.28 9.78 33.07 4.23
## KPNA6 15.17 13.25 8.76 12.58 6.87 20.99 3.55
## VIM 1537.27 1444.09 1194.11 1285.39 978.82 1034.06 372.76
## RTEL1-TNFRSF6B 2.16 2.08 1.49 1.89 1.02 1.77 0.80
## FAS 6.48 4.78 2.49 6.74 1.41 8.75 0.56
## RNASET2 10.73 12.68 13.29 17.52 15.89 15.62 17.89
## CD44 188.89 202.66 139.52 146.49 124.74 168.52 92.81
## KCNG1 50.38 29.74 26.77 65.08 17.21 86.12 9.11
## AGPAT4 0.77 1.52 0.76 1.19 0.82 1.06 0.67
## SLAMF7 0.33 0.84 0.24 0.26 0.15 1.49 0.28
## BTN3A1 3.08 2.86 1.72 1.99 0.98 3.03 0.64
## MIPEP 17.29 20.50 19.32 18.42 20.84 15.31 15.22
## PRKCH 4.61 4.78 2.97 4.87 1.73 4.90 0.85
## INSRR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## IFNGR1 10.18 11.09 5.35 12.17 3.18 15.78 0.69
## B4GALT7 21.71 19.36 19.90 20.86 19.92 21.21 22.67
## SH2D2A 0.23 0.18 0.21 0.06 0.07 0.13 0.10
## VRK2 12.50 7.93 4.88 10.86 2.52 16.21 0.66
## TNFRSF1B 2.54 1.94 1.90 1.00 1.80 0.66 1.84
## VEZT 16.60 15.77 8.37 16.70 4.42 23.64 1.70
## POU2F2 0.17 0.39 0.25 0.25 0.23 0.06 0.84
## BRD9 33.96 30.05 23.03 35.71 22.07 44.84 18.75
## SNX1 35.11 47.13 32.59 27.36 20.26 35.49 8.43
## TBPL1 17.82 23.51 15.49 21.44 12.25 24.94 6.50
## ARNTL2 10.09 3.54 2.36 5.77 1.69 6.33 1.05
## BCLAF1 64.74 54.61 23.75 46.33 17.17 76.08 7.37
## SLC39A9 24.76 23.92 20.39 27.97 16.05 44.57 7.20
## ANK1 0.31 0.60 0.44 0.17 0.26 0.12 0.13
## IBSP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TFB1M 16.16 14.31 13.06 13.76 11.47 12.12 6.26
## RABEP1 22.02 19.54 17.53 17.54 14.41 23.50 8.70
## HMGB3 34.87 42.43 40.00 30.36 38.67 24.04 40.94
## NUP160 28.44 23.30 13.53 21.14 10.47 29.65 5.77
## BAK1 15.19 15.37 12.66 19.92 12.15 29.15 8.88
## MUSK 0.01 0.03 0.04 0.00 0.01 0.00 0.00
## IKZF2 0.50 0.29 0.25 0.37 0.16 0.35 0.03
## GRN 80.19 87.93 96.01 88.24 112.49 99.99 126.23
## FAM13B 4.51 4.82 1.78 5.57 1.32 17.11 0.53
## ARHGAP31 4.83 5.49 3.51 4.32 2.97 4.97 2.06
## CENPQ 12.78 12.03 6.49 10.58 3.91 9.04 1.20
## SARS 111.35 69.36 69.36 139.39 60.54 180.03 55.34
## RANBP3 36.64 39.02 25.37 27.73 23.99 39.36 15.72
## ARID4A 1.56 1.37 0.49 1.57 0.32 2.88 0.56
## TSSC1 25.25 23.97 20.49 24.00 17.33 28.33 10.84
## PNPLA6 33.66 39.63 46.11 31.60 60.82 29.96 80.28
## IFT88 4.25 5.61 4.44 4.86 3.31 3.84 1.31
## ALG1 22.01 23.69 19.01 21.57 19.84 26.34 15.82
## ZCCHC8 11.39 9.44 5.85 16.50 2.62 22.10 0.81
## ABCF2 41.19 38.75 25.55 32.71 20.37 51.83 14.27
## CHPF2 29.40 28.46 25.34 31.02 22.07 36.26 17.01
## LRRC7 0.05 0.11 0.03 0.03 0.03 0.18 0.00
## FUT8 8.52 9.29 6.79 6.65 5.08 6.99 1.12
## UBA6 7.07 5.55 2.41 6.08 2.09 8.21 1.35
## GAB2 1.56 3.52 1.55 1.83 1.31 3.21 0.99
## ATP6V0A1 12.76 12.49 12.09 14.84 13.54 18.81 16.84
## PIAS1 8.22 10.16 5.08 7.39 3.82 10.25 1.69
## SLC4A7 8.08 5.72 1.47 6.57 0.90 16.12 1.81
## APBA2 14.30 14.15 9.21 12.66 9.39 17.25 7.66
## MAP2K3 68.65 75.56 61.53 62.11 50.73 65.14 46.37
## EFCAB1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMSB10 2791.51 2196.10 3202.43 3307.78 4100.49 3256.40 6114.14
## ASTE1 6.14 4.56 3.27 5.62 2.53 5.81 1.23
## RNF19A 4.93 4.70 1.87 5.97 1.11 8.48 0.44
## PEX3 11.89 11.72 9.64 15.63 6.41 16.00 3.23
## GABARAPL2 100.43 129.11 104.46 101.42 83.84 89.75 69.75
## MYOC 0.00 0.02 0.00 0.00 0.00 0.01 0.00
## SH3YL1 2.81 2.53 1.43 2.48 0.68 4.56 0.57
## FAM136A 83.75 77.99 63.37 89.01 55.50 92.96 40.07
## VCL 15.28 10.11 6.09 13.74 4.04 26.25 1.68
## DEPDC1B 7.09 7.93 3.23 4.84 1.99 4.63 0.98
## DAPK2 0.57 0.43 0.48 0.44 0.24 0.34 0.39
## NSMAF 17.73 17.96 9.54 15.74 6.85 23.87 4.11
## ADSS 43.96 46.42 23.92 38.36 14.35 42.40 5.51
## STAP1 0.02 0.05 0.00 0.05 0.03 0.00 0.00
## TIMP2 31.89 35.83 22.28 41.67 18.47 64.19 15.28
## RFC1 37.33 30.85 13.73 28.83 8.15 32.56 4.29
## TBC1D23 8.06 10.43 4.86 11.38 3.34 13.22 1.36
## CUL3 36.82 47.84 41.83 44.88 41.17 51.20 35.95
## MYOM2 0.37 0.21 0.30 0.72 0.37 1.21 0.40
## OTC 0.00 0.01 0.00 0.03 0.00 0.00 0.00
## CYP46A1 0.04 0.02 0.03 0.05 0.02 0.15 0.01
## ZZZ3 20.96 15.39 7.17 18.57 4.85 30.07 2.13
## SLC18A1 0.02 0.03 0.00 0.04 0.03 0.01 0.00
## USP2 0.40 0.80 0.56 0.67 0.56 0.43 0.48
## CASR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TUBG2 10.10 12.59 9.63 9.54 8.40 8.10 4.36
## RPL26L1 95.80 109.24 100.69 100.52 96.55 81.57 72.49
## FLT4 0.03 0.05 0.01 0.03 0.00 0.00 0.00
## NSUN2 49.53 55.64 32.38 53.90 22.50 64.78 11.40
## FBXO42 6.90 9.01 6.27 7.49 4.39 7.77 1.92
## MFAP3 14.78 13.23 5.71 14.89 3.39 30.78 1.35
## MRI1 42.35 47.33 32.80 47.60 20.40 52.91 8.24
## METTL1 42.10 41.76 44.57 34.69 43.64 30.84 42.53
## HOXC8 8.98 7.38 5.63 8.19 5.16 8.38 3.72
## AGA 18.51 21.96 11.89 20.85 8.78 18.85 4.71
## PI4K2B 7.78 9.45 4.96 7.86 3.93 8.89 3.70
## BOD1L1 14.43 11.65 5.46 13.55 2.19 19.06 1.10
## MAT2B 29.75 40.84 16.19 33.16 7.82 36.52 2.17
## TLL1 0.01 0.04 0.01 0.00 0.00 0.00 0.00
## EDC4 46.35 43.39 47.77 45.98 51.50 51.38 36.11
## TRIO 12.49 7.78 4.76 8.95 3.41 13.60 1.44
## VCAN 0.35 0.23 0.11 0.24 0.25 0.65 0.02
## CLEC16A 7.08 6.50 4.90 6.56 3.87 10.25 2.88
## MSR1 4.92 3.76 2.65 3.62 1.89 4.79 0.73
## CDH1 0.00 0.18 0.00 0.00 0.00 0.00 0.00
## SKIV2L2 38.90 33.51 25.32 29.03 12.00 39.02 3.75
## DNAH5 0.68 0.34 0.17 0.42 0.20 0.31 0.20
## ZFYVE16 6.88 6.86 3.43 7.48 1.71 12.32 1.40
## FAM65A 38.09 30.17 20.23 30.64 17.73 39.30 10.65
## C6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RAI14 17.70 15.18 6.96 13.75 6.51 21.18 4.00
## SOX30 0.04 0.01 0.00 0.06 0.00 0.06 0.00
## PNKP 36.11 36.01 33.67 28.63 37.57 44.53 45.62
## BEST2 0.01 0.02 0.00 0.00 0.01 0.16 0.00
## PHLPP2 2.26 1.88 0.95 2.39 0.78 4.43 0.36
## SPDL1 19.55 14.78 7.78 18.69 4.53 22.88 1.27
## STAU2 10.60 9.29 5.07 7.72 4.19 8.96 2.65
## PQLC2 19.40 20.74 19.37 21.02 20.18 27.08 20.63
## CTNS 6.54 6.90 5.04 5.84 4.77 10.93 3.57
## RTN4R 0.69 0.46 0.57 0.62 0.40 0.75 0.48
## PHF23 51.77 68.57 51.73 59.10 46.63 58.01 28.66
## CDH10 0.05 0.05 0.02 0.01 0.04 0.06 0.02
## INPP4A 2.69 2.40 1.45 2.37 0.71 3.57 0.34
## RAB27B 0.45 0.36 0.11 0.27 0.13 0.48 0.05
## PSMA4 205.27 271.19 257.89 209.90 261.98 167.40 256.11
## MYO16 0.16 0.17 0.08 0.16 0.07 0.10 0.06
## LSG1 17.64 17.21 10.20 19.55 7.32 27.24 4.26
## PARP3 11.83 9.47 6.60 12.47 5.18 16.63 2.32
## TNC 43.08 37.90 17.06 20.46 13.99 29.37 3.69
## THAP3 15.17 18.45 22.15 16.66 26.19 15.19 23.61
## FAM65C 0.16 0.07 0.04 0.07 0.11 0.07 0.06
## TDP1 5.08 5.58 3.35 4.59 2.48 5.47 1.64
## AIFM2 10.06 10.37 9.61 12.19 9.73 16.16 7.84
## C2orf83 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SPATA7 2.15 1.60 1.58 2.79 1.03 2.61 0.65
## MED17 40.79 43.83 20.91 41.77 10.80 53.85 2.33
## RETSAT 12.87 13.52 10.37 14.26 8.00 17.72 5.17
## CAPG 79.35 112.97 118.07 77.30 128.57 65.41 186.10
## AP2S1 369.09 396.54 454.55 392.12 594.41 321.27 859.49
## USH2A 0.02 0.01 0.01 0.02 0.00 0.01 0.01
## ZPBP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TG 0.01 0.03 0.07 0.00 0.06 0.07 0.00
## ADAM28 0.09 0.04 0.00 0.02 0.00 0.01 0.00
## BARX2 0.64 1.35 0.95 0.44 0.69 0.11 0.47
## DCUN1D1 11.92 9.24 3.69 10.26 2.54 15.48 1.03
## JADE2 9.91 9.31 5.09 6.70 6.40 9.59 6.17
## ZIC2 4.55 4.33 2.71 3.15 1.92 2.46 0.90
## LCP2 0.19 0.35 0.05 0.21 0.08 0.28 0.07
## TRIT1 22.11 23.94 20.50 20.32 15.32 20.61 10.19
## ADRB1 0.11 0.09 0.06 0.07 0.04 0.05 0.03
## GUCA2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CUL7 9.17 8.43 7.83 9.05 5.58 10.50 3.88
## CTNNA1 183.01 214.63 137.61 178.31 98.79 215.06 54.65
## PHKA2 8.06 5.86 6.32 9.40 6.03 10.85 5.66
## CNTLN 5.76 4.29 2.32 3.79 1.87 5.63 1.48
## EPHA3 2.51 7.63 1.84 2.78 0.83 2.64 0.22
## HSPA5 177.73 164.05 124.11 251.74 107.41 426.03 67.80
## DSG2 7.52 4.27 1.78 5.99 1.09 10.67 0.98
## GEMIN8 11.33 11.37 12.30 13.66 10.13 14.92 5.46
## OFD1 19.30 17.33 17.96 24.34 14.20 23.27 15.55
## GPM6B 0.35 0.45 0.15 0.34 0.16 0.29 0.09
## MAGEC2 99.42 92.38 49.76 89.58 26.31 100.78 5.46
## PREX2 0.01 0.01 0.02 0.11 0.10 0.03 0.00
## WDR37 8.18 6.80 4.05 8.94 2.80 14.06 1.11
## YTHDC2 3.79 3.62 1.62 3.54 0.84 5.66 0.39
## CTPS2 8.59 8.27 8.92 8.73 8.66 7.95 11.24
## ATP6V1H 26.91 30.26 24.82 31.09 20.03 43.14 9.91
## POLR2B 64.99 61.64 32.00 64.89 19.35 91.38 5.08
## FAM214A 6.55 7.24 4.71 8.72 2.42 13.01 1.03
## ARAP2 1.20 0.95 0.67 1.04 0.42 1.93 0.10
## TPR 49.73 49.30 39.75 45.68 22.55 45.96 4.85
## CP 0.13 0.07 0.05 0.05 0.08 0.55 0.09
## KIAA0556 4.72 4.50 1.74 4.26 1.22 8.16 0.63
## DTNBP1 7.93 11.15 9.07 9.24 12.07 9.61 10.96
## XK 0.27 0.19 0.06 0.27 0.06 0.52 0.01
## ANO2 0.01 0.10 0.06 0.01 0.00 0.01 0.04
## C12orf4 8.85 6.43 3.90 9.31 3.16 14.91 2.93
## SCML1 5.68 6.19 2.00 6.58 1.15 7.23 0.52
## WWC3 2.86 2.40 1.86 2.79 2.16 4.11 1.93
## ARHGAP6 0.25 0.43 0.25 0.38 0.29 0.27 0.01
## FAM184B 0.70 0.79 0.52 0.70 0.39 1.21 0.23
## MAP4 46.92 41.73 32.24 51.19 31.08 70.65 24.13
## GOPC 4.77 5.88 2.45 6.27 1.58 8.20 0.41
## ROS1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## USP28 5.75 3.92 1.86 3.51 1.25 7.17 0.49
## HDAC9 6.97 4.64 1.73 6.52 0.85 13.42 0.64
## TSPAN17 16.57 15.70 11.73 19.33 12.76 22.38 10.79
## NOP16 83.01 110.35 96.14 86.21 90.41 79.00 54.37
## CC2D2A 24.15 22.44 21.67 23.49 17.75 20.93 10.35
## RRM2B 8.83 8.37 3.66 10.19 2.48 18.56 0.73
## ZNF800 12.37 10.95 5.84 11.36 4.01 20.02 2.69
## TNFRSF17 0.00 0.00 0.05 0.00 0.04 0.00 0.00
## SNX29 3.62 2.52 2.57 3.08 1.80 5.62 1.21
## LMO3 0.16 0.17 0.08 0.18 0.08 0.17 0.01
## MRPS10 21.92 17.09 13.79 25.36 10.59 28.26 5.81
## GUCA1A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RSF1 6.74 7.33 4.74 6.75 3.41 8.80 3.10
## VPS13D 5.89 6.30 4.45 6.19 3.54 6.03 2.51
## CELF2 0.01 0.02 0.00 0.01 0.03 0.00 0.00
## FAM120A 33.23 35.39 19.03 32.91 15.92 50.07 14.69
## R3HDM1 7.85 8.40 4.27 8.52 3.59 12.88 1.89
## COL9A2 2.40 7.13 3.81 2.66 3.04 2.06 1.76
## KITLG 0.73 0.87 0.12 0.60 0.13 1.51 0.02
## ERCC8 5.99 5.38 3.34 4.84 2.90 6.88 1.78
## ADAMTS6 0.58 0.11 0.07 0.26 0.08 0.19 0.04
## H6PD 14.17 13.44 11.93 13.07 8.80 12.93 6.33
## VAMP3 63.60 56.08 36.52 65.37 30.27 92.62 16.05
## PER3 1.64 1.28 0.79 0.48 0.65 0.81 0.21
## UTS2 0.11 0.16 0.20 0.05 0.05 0.00 0.14
## TNFRSF9 0.75 0.36 0.43 0.27 0.14 0.31 0.13
## EPN3 0.01 0.06 0.01 0.00 0.00 0.05 0.00
## LTBP1 0.97 0.98 0.33 0.56 0.22 0.70 0.07
## RCN1 152.83 137.39 161.39 165.54 207.27 158.34 390.42
## ELN 0.01 0.22 0.01 0.00 0.06 0.00 0.00
## RFC2 78.58 68.77 62.94 55.13 72.28 48.76 47.37
## ARID1B 6.08 4.97 2.66 4.35 1.77 6.72 1.01
## CLPTM1L 127.72 152.79 115.65 120.49 103.22 144.55 48.56
## NEDD4L 19.85 12.53 12.89 17.17 10.57 20.69 5.84
## FOXP3 0.27 0.11 0.10 0.09 0.03 0.14 0.11
## PPP1R3F 0.40 0.64 0.57 0.44 0.66 0.78 0.37
## HEXB 132.27 145.63 147.55 152.13 147.12 160.23 127.10
## PTCD2 6.95 5.56 4.23 7.59 2.53 9.60 1.56
## KIAA2022 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## JKAMP 21.94 25.11 14.06 28.31 9.08 33.29 2.93
## DKK3 2.51 5.28 3.00 1.84 2.63 1.22 1.46
## ARHGEF5 0.36 0.38 0.37 0.23 0.27 0.27 0.12
## NFE2L3 22.08 22.57 13.74 14.37 7.95 11.42 3.51
## MCUR1 23.66 21.07 22.08 22.68 17.14 24.43 11.83
## LIMA1 13.66 19.50 9.03 12.42 6.68 13.68 2.21
## LETMD1 67.78 41.25 41.13 64.84 28.58 62.25 20.05
## SLC4A8 0.81 0.87 0.69 0.57 0.40 0.53 0.56
## LAMC3 0.05 0.19 0.03 0.10 0.06 0.08 0.06
## PTGER3 0.01 0.01 0.01 0.00 0.00 0.06 0.03
## TNIP3 0.12 0.06 0.00 0.14 0.03 0.15 0.01
## MAPK9 21.69 20.95 11.96 20.43 8.20 26.84 3.41
## COL23A1 0.02 0.01 0.06 0.04 0.00 0.01 0.02
## BCAR1 17.91 18.55 12.22 15.71 11.68 20.19 8.04
## FAM160A2 10.61 8.83 8.48 13.74 7.83 17.91 6.10
## HERPUD1 34.81 29.82 26.10 79.82 17.50 126.15 8.71
## HOMER3 82.26 90.37 87.63 89.54 96.25 85.93 87.63
## RAD51 41.67 27.40 24.69 29.12 27.19 14.99 18.13
## POLQ 2.62 2.00 1.22 1.94 0.73 1.92 0.43
## PIK3CB 9.57 9.65 5.65 8.20 3.42 11.44 2.02
## CYBA 95.55 126.68 133.82 91.25 172.69 71.87 200.12
## THOC3 29.36 27.76 24.47 24.65 15.42 21.81 4.76
## HEBP2 17.04 15.65 15.81 18.78 15.46 16.13 20.99
## MPHOSPH9 11.58 14.00 13.09 12.79 12.29 14.68 18.67
## PLEKHA5 4.14 4.93 2.40 4.08 1.50 3.65 0.47
## PRSS8 0.00 0.07 0.04 0.02 0.01 0.06 0.01
## SIKE1 37.08 29.68 35.17 27.37 36.98 41.62 33.65
## RRP12 78.93 83.73 84.92 77.40 92.51 74.94 87.97
## FNIP2 1.74 1.75 0.70 1.81 0.51 3.47 0.47
## MSMO1 8.04 8.27 4.75 8.81 3.63 13.46 1.86
## TTC17 35.11 33.39 23.16 42.84 17.30 71.29 11.85
## ALX4 0.47 0.42 0.23 0.43 0.24 0.52 0.21
## FSTL4 0.00 0.01 0.00 0.00 0.00 0.05 0.00
## FOXN3 2.70 2.67 1.73 2.31 1.04 3.52 0.76
## METTL24 0.00 0.03 0.00 0.00 0.00 0.00 0.00
## AKR7A2 42.56 52.44 56.95 36.46 54.61 27.52 43.14
## MRTO4 90.74 100.72 107.00 77.64 132.62 67.68 131.95
## NNAT 0.24 0.16 0.04 0.35 0.00 1.18 0.00
## USE1 96.29 101.14 116.01 81.76 129.20 68.49 112.89
## MCF2L2 0.27 0.26 0.34 0.58 0.08 0.33 0.39
## NRIP2 0.66 0.40 0.38 0.60 0.35 0.85 0.25
## LAMA3 1.10 1.88 1.06 1.27 0.95 0.52 0.44
## AP5M1 4.29 5.73 2.14 5.42 1.34 8.23 0.71
## ANAPC4 14.56 12.79 10.61 17.51 9.11 21.13 7.44
## KCNQ1 0.01 0.02 0.00 0.00 0.01 0.00 0.00
## TRAPPC3 52.79 62.58 53.89 52.83 47.84 70.49 35.10
## THRAP3 54.56 50.59 28.94 49.52 23.49 75.27 13.23
## PHPT1 82.26 89.94 118.41 82.61 144.31 66.38 176.02
## ENTPD2 0.05 0.07 0.00 0.00 0.06 0.04 0.08
## LY75 0.01 0.00 0.00 0.01 0.00 0.00 0.00
## ARID4B 9.69 9.05 3.30 9.18 1.76 15.38 0.98
## OPN3 1.79 1.42 0.83 1.37 0.82 2.89 0.36
## SDCCAG8 40.18 34.82 36.89 43.26 42.02 43.95 38.06
## PTPRN 0.87 0.62 0.56 1.06 0.40 1.80 0.50
## HHAT 2.23 1.80 1.26 2.08 0.64 2.52 0.43
## KIF1B 8.38 6.89 3.78 9.20 2.55 15.59 1.16
## FOXC1 7.64 8.25 4.82 5.80 3.39 6.32 2.17
## TBC1D22A 12.09 12.68 10.71 12.11 11.11 13.78 10.37
## SYNE2 2.03 3.27 1.52 1.44 1.19 1.44 0.82
## PLEKHH1 5.98 4.56 4.40 7.77 2.86 9.17 0.99
## ATP9A 11.51 9.84 6.23 9.35 4.63 14.31 3.61
## SPO11 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CBLN4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CHRDL2 0.04 0.00 0.00 0.01 0.01 0.08 0.00
## FAM168A 10.12 9.42 6.17 8.63 4.72 12.47 2.90
## RELT 12.73 11.94 8.65 11.31 6.57 13.56 4.58
## GALC 3.76 3.81 2.24 2.26 1.45 2.85 1.00
## NOP58 135.30 135.36 108.42 140.12 85.92 142.40 82.00
## SZRD1 80.90 75.89 50.58 71.19 47.76 103.31 33.01
## KCNH2 0.00 0.02 0.00 0.00 0.01 0.00 0.00
## CUL1 26.61 28.35 17.14 25.10 14.09 32.09 8.21
## FAM114A2 12.63 8.68 5.49 14.65 3.20 25.74 1.63
## CYFIP2 6.78 6.94 8.40 5.69 8.03 5.80 9.53
## TAB2 11.78 13.03 6.40 11.02 3.82 14.99 1.58
## GINM1 19.88 17.39 10.75 22.77 7.31 24.71 3.29
## EIF2AK2 17.94 13.71 6.00 13.17 3.86 22.59 1.81
## USP36 30.59 22.19 18.74 33.07 23.28 60.12 29.13
## KMT2C 9.74 11.84 5.61 9.74 2.71 9.52 1.25
## MCOLN3 2.14 1.75 1.05 2.60 0.76 4.38 0.53
## CCDC85A 0.02 0.03 0.00 0.00 0.01 0.03 0.00
## PUM2 21.38 18.85 9.43 17.98 6.00 28.23 2.62
## MRPL43 67.86 74.01 71.59 72.01 78.41 67.16 70.75
## ITIH4 1.75 2.49 2.19 2.10 2.43 2.83 2.49
## ITIH1 0.09 0.14 0.00 0.00 0.00 0.00 0.00
## C4orf27 26.63 25.89 25.21 27.30 25.30 20.47 23.63
## ZFR 28.06 25.63 11.52 29.45 7.90 47.75 2.99
## ZNF280C 1.40 1.01 0.25 1.30 0.11 3.65 0.01
## NPFFR2 0.27 0.46 0.19 0.56 0.12 1.16 0.04
## PHF21B 0.54 0.65 0.39 0.37 0.26 0.39 0.26
## TRAF1 26.04 16.79 12.56 19.12 8.95 16.98 6.03
## RC3H2 29.64 16.00 13.79 12.44 14.14 23.96 11.27
## PCGF2 34.34 39.65 37.02 32.66 38.62 33.52 33.00
## IL17RB 0.48 0.66 0.37 0.67 0.21 1.13 0.25
## TRAF3IP2 20.31 17.57 18.75 17.57 14.89 17.75 11.90
## GYG2 0.01 0.01 0.00 0.00 0.00 0.00 0.00
## DCBLD2 58.57 57.59 29.84 54.52 22.12 86.11 13.79
## SERPINB3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SOAT1 17.29 12.92 6.70 12.35 3.89 29.68 1.99
## PKP2 0.34 0.13 0.19 0.17 0.03 0.26 0.03
## MSH4 0.01 0.00 0.01 0.03 0.00 0.03 0.00
## F7 0.02 0.00 0.01 0.00 0.00 0.01 0.07
## GDI2 110.08 116.05 78.85 108.24 70.61 125.16 58.68
## PRDM1 0.56 0.10 0.08 0.22 0.03 0.13 0.01
## ATG5 7.31 8.47 5.42 8.03 3.81 9.42 1.34
## TMCC3 0.39 0.34 0.21 0.39 0.12 0.93 0.09
## PITHD1 45.77 51.50 44.58 54.58 42.49 51.49 23.61
## MTA3 18.26 16.34 13.80 13.92 11.94 13.17 8.52
## USP13 4.47 4.27 2.49 3.95 2.07 5.37 1.15
## ATP11B 7.64 6.44 3.30 5.92 2.43 9.44 2.09
## LAMC2 0.26 0.15 0.08 0.18 0.09 0.49 0.06
## CDK14 6.95 6.06 2.97 4.27 1.94 5.82 0.79
## SEC61A1 115.55 125.56 102.87 135.93 101.38 206.07 75.49
## PPP1R12A 12.62 10.57 4.45 11.59 3.66 23.70 15.93
## RASGRF1 0.03 0.01 0.00 0.04 0.04 0.06 0.01
## CAMK2B 0.08 0.23 0.20 0.07 0.23 0.05 0.23
## CROCC 7.46 6.13 3.95 12.26 2.83 14.26 2.04
## POLR3E 28.19 33.12 19.78 28.10 15.47 27.56 8.77
## ATP2B4 13.11 18.65 10.55 13.73 7.83 14.42 4.70
## ZC3H11A 40.62 38.19 19.16 37.66 12.74 55.17 4.17
## RIOK2 21.23 25.07 23.61 30.67 20.60 26.99 11.70
## YIPF1 15.71 16.68 14.11 21.97 13.93 26.91 11.72
## NDC1 19.23 18.47 12.61 17.16 10.10 18.69 5.82
## DGKG 2.37 2.68 1.60 2.38 1.23 5.42 0.64
## FLYWCH1 14.41 13.35 10.57 19.99 7.94 29.85 7.19
## UNKL 9.59 14.05 9.39 11.23 8.90 11.61 3.58
## TBXAS1 11.30 13.07 12.50 10.97 15.84 9.16 19.54
## PARP12 10.68 9.10 7.29 10.44 5.65 12.59 6.17
## ALDH18A1 36.20 37.83 22.55 32.41 15.90 42.40 7.51
## TARBP1 15.42 16.50 14.24 18.87 10.23 14.86 2.90
## PET112 8.90 10.53 11.45 9.78 11.02 8.89 6.50
## MXD1 4.34 2.74 2.95 6.04 2.55 18.90 1.50
## CDK17 7.25 6.15 1.39 6.16 0.90 11.26 0.18
## DNAJC25 21.26 10.60 13.19 32.34 10.79 27.48 6.76
## SLC2A3 17.07 20.41 17.73 21.12 16.83 30.28 27.19
## PSD 1.57 1.39 1.34 1.29 1.01 1.16 0.74
## CTDP1 6.24 8.26 6.19 6.31 6.14 6.83 4.78
## YBX3 276.75 217.81 207.94 221.10 149.48 237.96 67.25
## STYK1 0.21 0.18 0.02 0.22 0.08 0.50 0.06
## WNK1 16.71 15.43 9.55 12.64 7.10 21.53 3.52
## CCAR1 24.08 34.18 19.32 28.31 10.30 31.88 5.25
## OGFR 48.90 61.65 54.08 45.27 54.42 40.12 51.33
## GNA15 0.03 0.18 0.00 0.03 0.02 0.01 0.02
## CREB3L3 0.00 0.02 0.01 0.00 0.00 0.01 0.00
## PIGV 5.83 5.36 4.86 4.77 3.17 5.94 2.14
## PTPRU 4.14 3.59 2.45 2.23 2.27 2.14 1.59
## SNRNP40 54.31 58.35 57.60 57.37 55.36 57.62 31.56
## RIMBP2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## COL11A1 0.18 0.27 0.07 0.14 0.05 0.21 0.00
## QSER1 7.95 7.41 2.87 7.20 1.76 14.07 0.58
## MPC1 15.34 29.66 17.08 26.58 14.80 27.20 7.42
## ACAA1 24.28 31.92 32.19 38.16 28.03 38.91 19.32
## BCAT1 9.90 7.31 5.35 10.38 3.94 16.35 2.24
## HDAC7 19.99 15.27 11.92 18.05 12.10 23.44 8.79
## LZTS1 1.99 2.67 1.30 1.20 1.02 1.15 0.48
## PRDM6 0.07 0.10 0.06 0.28 0.02 0.11 0.04
## WNT8A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SPAG4 4.69 5.92 6.53 3.10 6.16 1.89 8.88
## NCKAP1 26.64 21.32 6.73 20.10 4.07 32.62 1.58
## MRPS35 51.53 51.86 36.73 53.14 27.89 56.56 19.67
## GUCY1B3 0.00 0.01 0.01 0.01 0.00 0.00 0.00
## SFSWAP 29.12 32.98 22.04 26.45 19.09 28.00 14.85
## TNK2 10.72 10.71 8.13 10.22 8.79 11.65 7.86
## MON2 4.68 4.43 2.42 6.20 2.17 7.17 0.61
## CDH3 0.03 0.08 0.02 0.04 0.06 0.11 0.00
## ARSF 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GPBP1 41.87 47.64 38.99 42.46 28.73 40.04 17.21
## DGAT2 3.56 2.77 3.19 2.39 3.36 2.67 2.63
## ZNF112 2.22 1.96 0.96 2.66 0.90 4.55 0.46
## CS 112.54 104.36 79.01 92.26 82.12 106.17 99.54
## LTK 0.18 0.21 0.09 0.15 0.11 0.36 0.11
## MRPS24 105.08 118.28 127.34 90.57 155.11 80.76 149.30
## ELMO2 14.03 14.46 9.56 18.55 7.92 30.89 4.48
## WAPAL 15.77 17.96 11.84 14.34 7.97 19.83 3.86
## VMP1 89.76 81.24 47.77 78.09 29.63 103.58 13.50
## APPBP2 4.06 5.06 1.83 4.56 1.25 8.63 0.54
## POLD1 58.22 71.62 80.73 39.31 121.46 23.75 144.53
## SEZ6 0.01 0.00 0.03 0.05 0.00 0.08 0.00
## EIF4B 264.42 220.60 147.39 213.58 108.18 276.54 80.77
## SLC6A16 0.19 0.35 0.46 0.17 0.80 0.34 0.66
## GLTSCR1 5.14 5.16 3.01 5.16 2.56 8.87 1.75
## SPHK2 10.14 10.69 7.41 12.23 6.02 17.31 4.53
## RPL18 3834.07 3286.14 4190.92 3776.12 4341.88 3515.31 4453.69
## CA11 3.77 7.47 7.44 2.53 13.22 2.24 13.90
## ISOC2 33.41 33.49 38.69 31.48 42.96 28.48 39.62
## U2AF2 159.07 116.64 75.54 132.50 53.76 193.05 30.45
## EPN1 79.26 89.99 77.87 69.75 77.66 77.75 80.79
## MED29 22.43 19.45 16.59 21.60 15.06 31.16 20.77
## AHRR 10.00 9.55 6.12 8.60 4.20 10.75 2.14
## GSC2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZNF275 4.75 2.94 2.02 4.88 1.40 9.35 0.82
## MTMR1 14.09 11.19 4.67 10.59 3.16 15.73 1.37
## GPC1 19.12 18.01 14.60 23.02 14.01 29.22 10.71
## ADCK1 2.51 2.56 2.07 2.97 2.11 3.22 1.98
## HAGH 42.58 57.36 52.10 39.84 46.75 28.07 25.18
## RNF4 24.91 24.11 13.42 24.96 9.48 37.84 3.24
## CASP8 21.80 17.47 10.70 18.50 5.77 23.10 2.33
## LIMCH1 9.91 8.21 4.71 8.34 3.96 11.68 2.62
## ASUN 31.94 37.65 25.27 30.52 17.41 30.68 5.89
## TM7SF3 28.42 26.69 17.62 32.28 10.61 55.45 5.57
## DLX3 0.05 0.03 0.04 0.02 0.04 0.07 0.00
## SPA17 11.32 15.80 13.34 12.52 10.05 8.88 7.08
## TSPAN32 0.01 0.04 0.00 0.01 0.00 0.00 0.04
## WISP2 0.01 0.13 0.06 0.03 0.09 0.07 0.01
## DMRT3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ST3GAL6 3.31 5.63 3.07 4.33 1.80 4.63 1.21
## ATP2C2 0.36 0.25 0.30 0.29 0.11 0.47 0.42
## NGFR 1.43 0.64 0.58 2.18 0.56 11.68 0.54
## CDON 2.90 2.50 1.15 2.50 0.95 6.61 0.40
## TAF2 9.57 7.14 2.43 7.49 0.70 14.57 0.08
## HIPK2 13.08 11.52 7.16 7.83 7.02 10.16 4.54
## TNPO3 14.41 12.65 5.73 14.08 3.27 30.12 1.65
## MEF2BNB-MEF2B 2.40 1.93 1.90 3.73 1.64 4.89 1.58
## RFXANK 113.07 122.72 169.08 90.97 254.69 72.72 421.62
## TMEM161A 40.41 40.53 36.46 39.02 40.74 44.42 35.46
## LPAR2 4.95 8.31 5.05 6.63 5.52 9.85 6.42
## CTSA 60.56 84.92 73.93 63.66 86.02 90.79 82.66
## SUGP2 28.64 34.58 34.21 33.31 34.01 31.16 32.42
## SLC12A2 5.99 6.42 2.89 5.63 1.47 11.21 0.67
## SNX24 17.86 13.48 9.65 17.64 8.76 16.58 5.68
## EYA2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CNN2 40.03 25.04 18.41 24.94 15.07 27.85 7.51
## ABCA7 1.64 2.36 2.14 1.39 2.87 1.39 5.81
## SNCAIP 0.22 0.06 0.14 0.23 0.06 0.28 0.05
## DDX20 13.77 12.69 7.30 12.37 5.15 13.35 2.31
## BTBD1 32.74 36.99 20.09 37.15 15.79 46.24 13.93
## FAR2 9.62 6.34 7.69 8.20 9.10 8.68 13.51
## BCAS1 0.06 0.00 0.01 0.00 0.00 0.00 0.01
## POU1F1 0.00 0.02 0.05 0.03 0.09 0.00 0.01
## CHI3L2 0.22 0.26 0.29 0.26 0.51 0.53 0.65
## SBNO2 22.60 23.65 16.38 20.41 13.38 25.86 9.52
## PMS1 5.14 6.32 3.85 5.09 2.44 5.85 1.45
## HMG20B 117.21 219.94 172.34 168.93 183.58 181.26 193.14
## CALCRL 0.19 0.05 0.01 0.08 0.01 0.33 0.00
## TAF11 24.41 25.64 20.33 24.33 16.37 25.58 10.87
## ANKS1A 2.89 2.79 1.68 2.33 1.23 3.20 0.83
## AP3D1 29.59 29.94 22.15 28.96 18.92 40.69 11.37
## ZNF76 8.51 8.05 6.17 9.73 5.39 12.64 2.67
## SLC9A3R2 50.12 60.16 57.87 47.39 67.88 52.13 56.49
## NTHL1 24.01 32.95 40.08 21.61 54.30 13.80 77.76
## UHRF1BP1 1.83 1.30 0.93 2.10 0.55 3.75 0.31
## GNAI3 39.56 40.55 23.62 42.33 17.01 54.84 7.94
## IPO5 71.16 54.75 38.15 51.18 32.00 66.00 24.48
## OAT 61.59 100.97 42.12 73.98 20.48 78.03 3.58
## WDR3 53.51 49.80 24.84 56.09 14.61 86.09 6.16
## PKN2 5.51 5.53 1.53 4.97 0.88 7.34 0.18
## WDR18 54.70 57.09 63.12 43.20 93.68 48.35 134.92
## TRAM2 7.62 7.14 4.37 6.08 3.88 10.14 1.74
## NTN1 0.30 0.15 0.13 0.15 0.09 0.27 0.03
## GLP2R 0.01 0.00 0.01 0.01 0.00 0.02 0.00
## MCM10 18.30 10.92 6.93 8.92 6.33 7.57 2.35
## DGKA 12.15 14.80 13.15 10.18 14.00 8.73 8.38
## ERBB3 66.05 98.97 87.94 61.08 94.57 48.31 84.02
## ROPN1 5.34 12.64 9.25 8.56 9.63 7.13 7.71
## ANKRD44 0.27 0.63 0.54 0.81 0.32 1.03 0.49
## KARS 236.69 227.78 256.92 217.17 298.05 218.31 514.15
## ADAT1 47.90 45.81 35.57 45.00 26.37 54.20 11.82
## PDIA5 8.14 8.67 6.24 7.90 4.73 10.63 2.20
## TBC1D22B 2.44 1.95 1.35 2.35 1.01 3.37 0.69
## NDUFB4 163.87 173.08 169.35 149.37 145.09 134.82 107.07
## SPEN 19.64 18.25 10.51 13.98 6.13 15.87 1.97
## MYLK 0.89 0.58 0.40 0.53 0.24 2.36 0.04
## ZC3H15 39.27 43.42 22.15 39.89 12.23 45.80 2.90
## MAP2K4 8.91 9.35 4.83 9.17 2.81 13.33 0.93
## TMEM206 12.10 9.73 6.54 11.23 4.90 18.20 2.56
## SNAP91 0.03 0.01 0.00 0.00 0.00 0.13 0.00
## SLK 11.21 10.66 4.40 10.73 2.72 13.96 1.31
## CYB5R4 5.86 5.71 2.51 6.05 1.36 7.09 0.26
## COL17A1 0.00 0.01 0.05 0.00 0.06 0.01 0.14
## GSTO2 0.24 0.31 0.10 0.40 0.25 0.77 0.15
## SEC61A2 2.14 2.42 1.49 2.71 1.16 3.41 0.86
## PRKCQ 1.26 1.19 0.95 1.22 0.69 1.22 0.36
## TLE2 5.39 5.75 5.52 4.23 5.35 4.29 4.37
## ASB1 24.90 25.77 24.42 22.72 28.07 20.96 29.96
## FAM107B 7.62 6.49 2.86 7.11 1.86 10.68 1.25
## ME1 13.05 13.68 5.92 12.33 4.68 15.44 1.39
## TBC1D1 30.02 29.29 26.44 20.99 26.50 17.73 21.58
## CDK13 9.86 11.50 5.81 11.30 4.53 21.30 2.31
## MTHFD2 165.39 95.11 59.20 253.90 33.32 338.80 15.74
## SLC9A7 2.85 1.81 1.05 2.85 1.36 4.11 0.74
## FOXJ2 8.69 6.43 4.37 8.13 3.60 12.95 2.59
## YBX1 988.09 1062.52 723.34 964.23 535.51 1036.52 189.58
## PDE4A 12.57 11.63 7.97 7.97 7.31 8.17 5.73
## PPP2R5A 10.61 11.59 7.08 12.39 4.51 16.48 2.52
## CTNNA2 0.00 0.02 0.00 0.00 0.00 0.00 0.00
## ELAVL1 52.02 48.70 30.64 40.53 23.00 50.49 13.22
## TIE1 0.96 0.39 0.49 0.61 0.25 0.59 0.28
## DIP2B 5.77 5.11 3.01 5.91 2.47 11.56 1.42
## SMARCD1 54.43 46.73 28.80 41.61 22.53 67.52 10.27
## KDM4A 12.53 11.17 6.61 17.01 4.65 28.41 2.82
## NFYC 31.48 31.94 21.86 26.95 18.24 37.04 12.60
## ZMYND12 0.09 0.03 0.02 0.17 0.00 0.05 0.03
## SLC9A3 0.01 0.03 0.00 0.01 0.03 0.02 0.01
## NGEF 1.37 1.13 1.15 0.61 0.85 0.95 0.43
## ASPM 5.53 7.35 3.96 3.14 2.48 2.03 0.77
## CD84 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ELOVL1 57.13 53.57 42.82 62.10 40.12 71.41 30.18
## SPI1 0.00 0.06 0.08 0.00 0.04 0.12 0.00
## ZNRD1 42.43 35.99 43.51 45.60 42.02 42.00 31.08
## MPPED2 1.03 1.84 0.69 1.05 0.47 1.25 0.38
## CLDN18 0.02 0.01 0.00 0.01 0.04 0.03 0.00
## ZBTB11 5.54 5.77 1.67 5.70 0.83 8.70 0.17
## ATXN3 8.58 6.11 5.57 6.09 4.10 10.99 1.97
## GOLGA5 12.05 16.20 10.38 15.41 9.61 17.08 6.97
## FGFR2 0.18 0.19 0.06 0.12 0.09 0.11 0.01
## LRRC40 5.74 6.63 1.82 5.31 0.64 6.65 0.05
## ISOC1 11.93 10.04 5.46 8.01 3.40 9.55 1.32
## EML1 3.30 3.62 1.82 2.62 1.69 3.23 1.18
## TRMT11 10.69 8.36 4.89 7.82 1.96 8.02 0.21
## THUMPD1 14.67 14.70 5.89 13.52 3.10 19.44 1.00
## MSANTD3 34.27 36.44 27.06 30.22 21.73 34.21 11.15
## KIF26A 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## ATG2B 1.24 1.74 0.88 1.67 0.45 3.27 0.16
## ARFGEF1 12.73 10.15 6.25 10.41 3.62 10.05 1.55
## ACSM2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZFAT 2.44 3.66 1.98 2.29 1.50 2.45 0.44
## MTFR1 13.78 12.49 5.86 15.55 4.56 20.30 2.00
## STAG3 0.92 1.39 0.88 1.23 1.25 0.69 1.27
## FECH 11.14 8.67 4.73 10.75 3.37 16.47 1.21
## MYO9A 2.56 1.75 0.84 2.09 0.64 3.59 0.21
## DDX3Y 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PFKP 83.04 76.55 51.38 64.55 44.43 75.37 27.91
## IDI1 13.38 18.82 11.65 15.83 8.90 14.58 4.26
## SP100 25.07 20.30 15.37 17.77 11.91 20.61 9.48
## KLF6 7.87 6.26 3.11 6.08 2.53 12.56 2.25
## PPAP2A 14.38 14.29 11.16 11.36 7.81 10.48 3.68
## NEO1 2.22 2.45 1.54 2.15 1.03 2.92 0.59
## TRAM1 68.97 56.58 21.43 63.19 14.05 118.39 13.20
## PHKA1 5.43 4.53 3.28 4.85 1.97 6.25 0.84
## TNFRSF1A 51.60 71.08 43.07 63.72 41.83 76.24 30.19
## CACNB1 4.87 3.89 2.55 5.46 2.43 8.59 2.31
## EVI5 3.03 2.81 1.15 2.85 0.53 5.61 0.14
## STOML1 6.49 5.93 5.37 7.49 6.45 8.30 5.10
## PKM 1134.29 1306.62 950.10 1155.27 938.07 1377.31 601.47
## DHX29 12.62 12.60 6.75 12.82 4.32 18.01 1.29
## DNTTIP2 60.76 61.85 71.88 64.00 72.73 62.93 83.62
## METTL22 11.33 11.79 10.90 11.88 11.56 13.96 10.27
## TP53BP1 12.63 11.12 8.62 10.16 7.53 15.93 4.47
## TRO 2.13 2.04 1.96 3.08 2.31 3.61 1.90
## RRP15 33.07 27.51 17.65 28.88 10.26 38.47 2.77
## RHOA 271.96 283.03 188.17 268.01 149.79 290.97 96.01
## DHX8 33.36 40.67 40.18 34.56 40.44 41.59 30.42
## PRKCZ 7.98 9.12 6.35 7.48 6.54 6.90 4.62
## ZFY 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## IARS2 68.60 70.09 39.26 61.63 24.63 65.75 8.37
## SYT1 4.02 1.28 1.01 4.37 0.52 9.70 0.18
## NAV3 0.47 0.03 0.00 0.61 0.03 0.52 0.08
## IDH3G 48.89 62.74 61.17 51.40 79.89 44.48 94.95
## ROGDI 6.54 9.70 8.79 10.48 10.11 9.65 8.33
## PDZD4 4.53 3.91 3.64 3.50 3.72 2.79 4.37
## ATP2B3 0.00 0.00 0.04 0.00 0.00 0.02 0.00
## ROCK1 6.01 6.00 2.12 6.50 1.04 10.37 0.47
## CBFB 43.41 45.89 18.62 40.53 10.28 69.84 3.18
## PDK3 4.76 4.95 3.54 3.62 2.62 3.97 1.32
## HYAL2 18.55 20.90 15.19 12.78 12.47 12.09 3.66
## HDAC4 2.06 2.31 1.18 1.49 1.16 2.11 0.76
## RASSF1 14.50 12.10 12.93 11.68 13.02 11.53 9.70
## FGFR3 1.80 2.90 2.49 1.82 1.69 2.00 1.65
## IFI35 32.45 41.62 47.78 27.49 44.69 15.54 39.88
## HEATR6 11.79 7.26 4.74 8.42 2.81 12.14 1.50
## COASY 58.33 80.23 83.22 44.34 101.58 40.56 99.52
## PLEKHH3 11.86 12.71 11.63 15.55 11.97 13.95 5.12
## MEF2A 12.13 10.09 4.06 11.63 2.43 20.53 0.69
## OTUD5 42.72 46.39 37.44 42.82 35.44 45.73 30.71
## TFE3 20.54 19.84 12.64 23.94 11.05 31.58 5.71
## TBC1D25 5.05 6.18 3.44 5.51 3.11 5.13 1.72
## ACSL4 4.80 4.88 1.65 4.95 0.82 7.67 0.24
## INPP5A 12.65 12.58 8.82 13.11 6.92 19.03 6.01
## GPKOW 26.66 22.10 22.87 20.14 22.35 17.97 15.55
## GRIPAP1 17.87 18.37 13.43 17.79 10.64 19.00 7.10
## FTSJ1 62.78 62.99 53.55 55.85 51.50 53.71 34.17
## PRR11 12.97 12.59 7.58 7.52 6.63 8.42 4.38
## REEP1 0.67 1.12 0.64 0.66 0.60 0.71 0.33
## ATP11A 5.46 4.47 2.15 4.51 1.24 10.00 0.76
## POLR1A 7.11 6.59 4.89 6.24 3.82 8.55 2.47
## LAPTM4A 101.80 106.76 72.78 98.31 55.77 105.33 29.77
## TTC7A 3.53 2.39 1.60 2.75 1.99 3.64 1.22
## IP6K2 27.25 37.33 27.10 30.73 20.68 38.29 10.15
## STON1-GTF2A1L 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SRBD1 7.89 5.93 3.70 7.81 2.10 10.09 1.00
## CYFIP1 52.64 45.89 37.29 43.52 23.67 49.10 13.53
## KIF2A 17.31 17.23 7.61 14.37 4.78 27.13 1.98
## RASGRP2 0.09 0.10 0.22 0.15 0.30 0.18 0.38
## PSME4 33.71 44.88 39.88 34.89 38.53 32.70 36.71
## IFT80 9.37 9.65 4.94 12.66 2.60 18.11 1.22
## SIRT2 12.79 13.29 11.49 13.08 10.21 18.53 7.70
## ERLEC1 50.41 51.23 30.95 56.66 19.44 63.95 11.99
## PPP2R5B 3.86 3.97 2.60 3.98 2.09 6.21 1.29
## PYGM 0.12 0.09 0.04 0.17 0.05 0.41 0.03
## PAGE1 10.31 5.93 11.04 7.35 9.80 6.48 20.88
## PITX1 0.47 0.34 0.43 0.41 0.32 0.47 0.18
## TRPC7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MAST4 0.61 0.32 0.21 0.47 0.24 0.48 0.33
## GPR116 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SDK2 0.04 0.03 0.03 0.00 0.00 0.01 0.00
## ADAM7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NUP133 25.94 31.07 22.70 26.59 15.27 21.74 7.75
## NUCKS1 67.44 86.21 87.20 62.84 96.91 53.51 115.09
## VPS35 32.11 27.67 16.94 28.81 13.18 42.80 7.76
## DNAJA2 44.04 44.70 27.36 43.94 16.88 51.47 9.54
## BCL3 8.66 11.27 8.98 10.82 7.16 13.47 3.66
## KCNAB2 5.71 6.25 4.41 5.11 3.62 5.84 3.37
## ABCC9 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GAL 20.19 10.74 13.44 15.71 13.71 16.20 11.64
## CLEC2D 0.66 0.56 0.17 0.52 0.18 1.72 0.00
## FUNDC1 17.71 20.49 17.54 17.23 12.17 14.29 4.89
## MAOB 0.54 1.82 0.96 0.67 0.70 0.68 0.43
## RORA 0.54 0.35 0.22 0.24 0.47 0.86 0.11
## DRD4 0.76 0.75 0.77 0.99 1.01 0.71 1.38
## TGFBR3 0.29 0.43 0.24 0.25 0.16 0.40 0.17
## KIAA1107 0.26 0.12 0.05 0.18 0.02 0.41 0.00
## PLA2G10 0.05 0.08 0.05 0.08 0.00 0.14 0.00
## HES2 0.03 0.09 0.00 0.08 0.03 0.01 0.01
## ATP1B3 151.44 184.42 160.06 176.48 143.79 202.66 81.49
## NEDD4 9.46 5.40 2.56 7.12 1.52 12.90 0.44
## PIGB 10.32 11.11 9.76 8.96 7.30 5.55 4.89
## MAPK6 21.82 19.10 6.65 24.50 3.59 53.12 1.23
## GNB5 16.49 12.10 7.72 12.51 7.19 16.53 4.11
## RAB27A 7.53 5.62 4.83 6.90 4.18 7.96 3.12
## CECR5 27.54 29.47 24.97 21.98 22.05 21.69 10.91
## UFD1L 76.12 96.21 86.28 88.65 97.21 83.89 73.23
## LRP6 4.74 5.02 2.58 4.48 1.70 7.48 0.73
## GUCY2C 0.00 0.01 0.01 0.02 0.00 0.01 0.03
## SCT 0.00 0.10 0.00 0.00 0.00 0.12 0.08
## PHRF1 13.36 12.39 11.04 11.14 10.79 13.48 11.44
## IKBKAP 12.93 15.12 8.94 13.32 6.08 18.63 2.22
## NUCB2 35.24 34.90 31.34 41.93 26.06 35.83 23.60
## PFN2 125.65 144.90 75.42 118.76 59.75 105.08 23.54
## PTPN3 7.39 6.74 3.97 6.22 3.17 8.53 1.83
## SPTB 0.29 0.27 0.15 0.23 0.07 0.14 0.06
## DAPP1 0.02 0.02 0.01 0.00 0.00 0.03 0.00
## FGF10 0.00 0.02 0.00 0.00 0.02 0.00 0.00
## SLC44A1 9.16 9.87 6.64 11.04 4.63 15.15 3.47
## TMEM260 2.32 1.74 1.54 2.54 1.07 3.79 0.63
## SMG6 9.38 9.40 8.39 11.15 7.84 13.99 6.90
## EXOC5 9.48 8.47 3.82 8.39 2.48 14.59 1.60
## CLTCL1 4.49 6.36 5.58 3.60 5.65 2.75 4.84
## FGF22 0.23 0.30 0.36 0.35 0.14 0.32 0.53
## FSTL3 18.61 20.24 19.77 15.94 18.52 15.39 17.74
## DGCR2 10.52 9.84 7.50 10.13 5.73 13.96 3.58
## RNF126 48.20 62.05 46.33 41.82 48.57 40.51 35.73
## MNT 9.94 7.60 5.70 9.44 3.82 12.84 3.45
## ZXDC 12.25 10.50 7.64 12.64 5.62 17.41 2.32
## JMJD6 25.52 32.54 30.22 31.46 34.64 40.95 40.43
## POLB 21.12 20.05 17.04 23.13 12.95 24.61 9.82
## ST6GALNAC1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## WIPI1 15.67 17.03 13.02 25.72 10.08 38.41 3.56
## FRMPD1 0.05 0.03 0.01 0.09 0.00 0.06 0.00
## GBA2 29.77 34.26 26.42 33.10 20.79 47.14 12.51
## NDST1 9.70 9.63 5.99 8.05 5.06 11.99 3.05
## ASNS 150.17 58.16 83.08 214.08 73.09 256.10 62.86
## AP3M2 13.43 6.84 6.80 8.59 4.96 10.61 2.98
## CNGB1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ST6GALNAC2 0.38 0.44 0.61 0.58 0.89 0.59 1.95
## CHAT 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PABPC1 1421.80 1064.07 973.08 1516.40 692.16 1815.08 419.75
## TESK2 1.45 1.74 1.06 1.85 0.62 2.26 0.49
## C16orf80 38.02 39.74 30.26 34.38 24.94 43.47 9.55
## CSNK2A2 49.61 46.21 32.23 53.10 23.97 78.76 14.17
## PTPN21 1.79 0.99 0.82 1.39 0.39 2.64 0.59
## EIF2B3 44.17 35.78 37.47 39.26 37.43 33.37 40.23
## CAMK2A 0.03 0.03 0.02 0.00 0.00 0.05 0.00
## TCOF1 61.38 59.92 55.26 42.71 66.87 39.51 124.49
## CDC42 125.87 124.58 75.48 128.04 57.39 166.48 35.25
## OSBPL3 6.93 3.77 3.97 4.60 3.49 7.99 2.46
## EPHA8 0.01 0.03 0.04 0.03 0.02 0.03 0.01
## SLC12A3 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## RAD18 12.70 9.39 5.55 9.82 5.31 11.58 3.87
## ATP2B1 9.46 15.99 5.74 8.54 2.33 11.24 1.06
## TRPM5 0.01 0.00 0.00 0.00 0.00 0.00 0.00
## NCK2 9.62 12.87 6.42 7.69 4.27 9.77 2.52
## MAP4K4 25.98 22.46 13.93 19.71 12.75 28.52 8.69
## MGAT4A 0.71 0.67 0.60 0.90 0.51 0.66 0.33
## RPL31 4895.55 4098.81 5373.45 4432.33 5206.28 3556.43 3692.27
## WDR1 106.91 87.63 65.19 102.49 59.75 156.58 41.92
## SNX13 9.19 6.50 3.18 8.32 1.73 14.79 0.68
## MS4A12 0.00 0.00 0.00 0.00 0.02 0.00 0.08
## ARHGAP10 6.28 6.06 5.27 5.42 4.74 7.16 3.85
## RPS6KA2 4.78 2.54 1.99 5.43 1.43 9.24 1.15
## ING3 17.04 20.42 9.47 14.38 4.82 14.86 1.42
## VASH1 4.13 4.82 3.92 3.17 4.11 3.40 3.27
## LMCD1 12.11 12.31 11.32 8.03 10.17 6.26 8.32
## WBSCR22 113.36 115.64 106.56 98.48 104.62 92.22 83.47
## SEL1L 8.17 6.20 3.32 9.30 1.97 18.30 1.13
## TRIP13 37.33 35.60 26.03 25.61 25.22 21.77 16.92
## ATP6AP1 56.04 66.79 50.52 51.79 46.04 58.81 40.61
## TCF3 38.32 37.12 29.25 31.88 26.06 36.66 17.66
## TRIB2 26.94 55.05 23.43 23.23 19.64 21.16 8.03
## DAZAP1 114.32 123.65 102.35 105.66 99.70 101.03 74.20
## MBD3 41.23 55.74 51.37 35.67 59.54 29.84 64.53
## PRLH 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## HLTF 21.62 12.21 6.11 13.89 2.79 16.32 0.50
## FAM50A 102.82 128.52 140.97 117.66 157.67 106.43 174.80
## FAM3A 39.88 36.39 38.46 40.01 39.83 34.68 36.33
## CPSF1 57.61 74.26 80.91 54.10 100.95 57.87 104.09
## MYO3B 0.05 0.02 0.04 0.02 0.00 0.02 0.00
## CYBRD1 5.17 6.01 3.76 5.62 3.02 8.85 1.63
## CDH19 8.57 9.28 4.21 6.72 2.61 7.71 0.85
## PDCD2 81.78 90.99 85.02 73.87 65.69 69.72 36.89
## SLC6A15 22.07 24.28 10.81 19.38 6.74 24.87 2.73
## RDH11 31.92 35.67 27.05 34.52 20.82 46.84 13.99
## PRKACA 44.13 41.91 26.52 38.05 23.16 56.76 13.23
## LPHN1 13.23 15.99 11.14 8.00 10.49 8.44 7.41
## SPP2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ACTN1 85.38 60.55 35.36 55.75 26.63 89.61 17.67
## ZFYVE26 1.92 1.56 1.13 1.71 0.96 3.09 0.62
## RPS6KA6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## EPN2 11.63 8.03 6.53 9.44 5.79 11.41 4.41
## PTPN18 12.37 9.97 7.72 13.31 8.49 14.60 8.24
## LIMS2 0.18 0.36 0.14 0.15 0.24 0.10 0.32
## ASIC4 0.10 0.15 0.09 0.21 0.03 0.35 0.12
## SPEG 5.60 5.43 5.15 4.99 5.65 3.59 6.64
## LNX1 2.04 2.05 1.22 1.77 0.62 2.03 0.17
## ALDH3A2 25.45 23.56 15.54 32.12 12.13 45.75 6.63
## TFRC 41.41 33.51 18.18 48.34 15.49 89.17 6.58
## SREBF1 42.39 62.73 46.69 28.21 42.46 18.00 24.43
## TRPC5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## AFF4 9.23 9.07 3.39 9.36 2.01 20.23 1.11
## UBE2D1 7.48 11.14 3.28 11.67 0.93 12.48 0.25
## MPP5 5.85 5.77 2.90 5.83 1.82 7.06 0.57
## RHOBTB1 2.57 2.69 1.65 3.04 0.83 3.06 0.48
## SMC1A 24.34 21.28 10.79 13.51 10.10 22.19 7.48
## HSD17B10 178.93 198.32 204.92 217.41 227.82 214.35 198.41
## MARK2 8.48 10.49 5.50 7.14 4.62 11.19 3.39
## HMMR 5.18 6.77 2.69 3.96 1.43 3.20 0.27
## CHFR 10.77 10.83 7.05 11.79 4.94 16.11 2.29
## TRHDE 2.41 2.94 0.74 1.80 0.45 1.44 0.28
## P4HA2 15.22 15.12 14.43 17.13 12.66 23.09 10.25
## FCGR2B 0.12 0.13 0.16 0.06 0.11 0.06 0.10
## NFATC3 9.92 11.45 7.04 9.21 5.58 14.02 2.80
## TRNT1 16.23 14.29 8.09 15.26 7.11 18.41 4.09
## ACADVL 323.01 483.29 424.34 395.78 433.22 411.76 406.90
## STK10 15.69 18.53 11.05 17.22 12.51 22.65 11.53
## FBXW11 20.18 20.94 10.28 20.20 7.75 32.73 4.11
## ACAP1 2.53 3.77 7.21 3.10 6.98 3.38 13.85
## CRMP1 2.10 1.03 0.92 2.02 0.71 3.49 0.37
## EVC 5.17 3.81 2.58 4.84 2.06 7.94 1.57
## DERL2 73.21 76.88 70.53 95.49 66.56 98.35 49.08
## SIDT1 0.12 0.14 0.10 0.05 0.01 0.06 0.02
## NDE1 26.28 27.95 16.18 29.94 8.96 43.31 6.49
## MRVI1 0.01 0.02 0.00 0.12 0.01 0.06 0.00
## TMEM38A 1.31 2.33 1.67 2.09 1.72 1.90 1.11
## AP1M1 73.95 74.34 62.11 68.70 60.89 82.72 52.40
## PVR 38.65 26.77 20.10 48.10 18.26 72.84 14.92
## IKBKG 30.35 30.58 26.00 39.29 25.67 44.62 14.55
## XRCC1 16.35 19.00 13.84 8.34 11.91 8.63 5.26
## SCARB1 40.85 57.99 47.16 38.90 40.84 38.25 22.48
## CYP2W1 0.02 0.15 0.02 0.00 0.01 0.16 0.00
## MCM2 77.85 49.52 38.74 52.41 31.95 50.04 18.44
## MOV10L1 0.15 0.01 0.02 0.11 0.00 0.19 0.01
## PANX2 0.82 1.03 0.53 1.91 0.79 1.92 0.49
## SELO 11.10 12.51 12.93 12.85 15.18 11.88 15.82
## TP63 0.00 0.00 0.00 0.01 0.00 0.00 0.00
## ALPK1 3.88 4.67 3.78 3.35 1.91 5.23 1.45
## LLGL2 1.45 1.90 1.68 1.33 1.30 1.11 1.63
## PDE8A 6.87 9.50 4.87 7.02 2.66 6.47 0.89
## CLCN4 0.78 0.74 0.45 0.46 0.38 0.95 0.13
## NLE1 20.82 18.72 16.81 14.63 17.03 18.55 13.13
## SDHA 62.79 70.81 78.48 54.00 88.52 41.50 88.14
## SMARCE1 91.32 91.83 71.32 74.55 63.26 80.66 48.00
## FNDC8 0.10 0.04 0.04 0.14 0.04 0.19 0.00
## GSDMB 2.13 1.86 1.94 3.08 1.60 4.66 1.36
## KDM5A 11.31 9.07 6.31 11.35 4.13 16.31 2.52
## ADAM11 2.30 2.62 1.64 1.98 1.62 2.34 1.26
## PPP2R3A 4.07 4.10 1.87 2.91 1.77 4.36 1.14
## FERMT2 10.70 9.33 5.56 9.82 4.92 14.68 4.25
## ABCB11 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DHRS9 0.00 0.02 0.02 0.00 0.00 0.00 0.05
## CD5L 0.08 0.14 0.03 0.06 0.01 0.02 0.01
## PTGS2 3.81 13.27 4.69 1.47 2.03 2.03 0.86
## IGF2BP2 19.72 27.01 17.05 19.97 13.32 21.08 9.88
## MAP3K13 13.32 11.29 8.34 12.32 6.09 11.41 2.87
## ST6GAL1 15.49 16.15 10.41 13.88 9.17 17.88 5.93
## TBX21 0.00 0.03 0.01 0.01 0.01 0.01 0.00
## FRY 0.11 0.25 0.09 0.18 0.04 0.92 0.06
## PICALM 51.55 44.99 25.81 45.75 18.92 79.71 11.04
## NSF 12.48 12.34 7.44 13.39 5.95 21.72 2.81
## GLI2 0.83 0.89 0.57 0.47 0.56 0.51 0.19
## CLASP1 6.67 6.50 3.82 6.21 2.39 10.53 1.23
## MRPS34 124.54 167.14 178.27 96.81 232.18 77.58 246.82
## NOTCH3 1.48 0.78 0.66 1.15 0.50 2.52 0.30
## CLNS1A 251.87 275.82 222.40 222.47 158.65 196.49 74.64
## PPP2R2C 0.03 0.14 0.14 0.14 0.02 0.10 0.00
## TEAD2 15.03 14.60 11.25 11.63 9.98 10.00 5.77
## EED 31.04 32.58 24.68 28.11 19.55 27.99 8.92
## CDHR2 0.01 0.06 0.00 0.12 0.01 0.04 0.08
## SNCB 0.10 0.28 0.20 0.12 0.14 0.07 0.12
## TSG101 96.55 91.94 68.34 89.82 48.25 100.37 20.30
## C17orf85 12.56 13.05 8.50 14.29 7.22 20.61 3.95
## ATP2A3 0.19 0.24 0.19 0.10 0.13 0.11 0.13
## CA12 0.04 0.13 0.11 0.16 0.07 0.06 0.02
## MGLL 20.41 13.45 10.59 16.06 11.75 14.08 10.66
## NTN4 1.55 1.54 0.85 1.41 0.26 1.66 0.14
## BCS1L 36.62 33.91 37.94 46.85 34.63 53.91 35.25
## NUAK1 1.28 0.98 0.69 0.60 0.66 0.57 0.34
## DPP8 18.31 18.13 14.61 12.62 15.77 14.00 10.43
## SLC24A1 6.38 4.75 3.86 7.41 2.45 8.15 1.43
## ZNF532 12.80 8.18 4.09 6.94 2.82 13.50 1.14
## SCARF1 0.12 0.05 0.08 0.19 0.05 0.50 0.05
## LMAN1 24.25 20.71 10.59 26.54 5.57 34.45 1.59
## PTPLAD1 60.10 53.96 33.91 49.86 25.20 61.29 12.06
## IPCEF1 0.03 0.04 0.00 0.09 0.00 0.13 0.00
## ZZEF1 3.83 3.34 2.32 3.77 1.74 6.86 1.08
## NOX3 0.34 0.06 0.12 0.28 0.08 0.33 0.04
## ENO1 1892.59 2031.07 1630.12 1684.38 1584.19 1753.53 1024.46
## SLC12A1 0.01 0.02 0.01 0.00 0.00 0.00 0.00
## C19orf10 116.63 127.31 140.97 114.44 176.98 116.67 171.34
## ANO8 4.30 5.26 3.20 4.56 2.24 5.13 0.75
## TUBE1 8.50 6.44 4.53 14.80 2.70 28.52 2.07
## ARHGEF10L 3.50 3.55 2.92 3.61 2.24 4.51 1.60
## TXK 2.77 1.35 0.54 1.05 0.58 0.85 0.30
## WSCD2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## KCNQ2 0.05 0.08 0.02 0.11 0.10 0.13 0.00
## TACR2 0.51 0.79 0.26 0.41 0.20 0.97 0.23
## ACTR6 33.68 32.98 19.36 38.49 9.75 44.34 1.86
## TIPIN 38.28 28.34 25.49 32.98 21.04 27.61 11.70
## SRI 213.25 233.80 241.16 185.37 205.57 136.37 126.69
## EIF4G3 23.94 20.68 11.81 19.99 6.87 28.96 3.39
## NUP37 57.95 44.98 41.88 51.90 37.26 47.26 26.26
## SEMA3A 8.68 4.24 2.89 5.57 1.63 12.59 1.18
## GTSE1 3.96 6.01 2.68 2.18 3.33 1.78 0.90
## SEMA3C 4.35 5.57 1.06 2.79 0.60 3.74 0.32
## TTC38 9.77 8.62 6.80 10.40 5.05 13.24 4.49
## ACAT1 56.69 65.01 65.74 55.27 64.38 43.10 50.70
## GRAMD4 4.26 5.60 2.76 3.73 2.57 6.16 1.25
## CELSR1 5.66 5.33 3.91 5.32 3.44 7.31 1.37
## WNT8B 0.02 0.00 0.00 0.00 0.00 0.01 0.00
## ZNF638 44.41 54.50 42.57 40.84 31.23 36.49 18.74
## SLC25A40 8.66 5.91 3.43 7.64 1.90 11.69 1.41
## TIMM21 20.03 21.44 13.56 19.52 11.20 18.70 5.08
## ADD2 6.90 4.86 3.70 5.27 2.71 5.59 2.69
## FGF4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RASAL2 5.15 1.59 0.69 3.07 0.73 7.51 0.27
## VPS9D1 7.66 9.45 8.16 10.43 7.14 10.52 6.28
## ZNF37A 3.13 2.80 1.61 2.58 0.96 4.82 0.72
## MARK3 31.91 34.00 26.87 36.63 23.97 46.54 19.78
## SLC25A3 597.88 596.59 639.93 578.17 689.24 548.82 593.51
## FNDC3B 5.95 6.63 3.26 6.18 3.36 8.82 1.80
## FOSL2 3.80 3.32 2.37 2.53 2.10 4.39 1.52
## CACNG5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CACNG4 0.00 0.02 0.01 0.00 0.00 0.00 0.00
## FRYL 7.97 9.14 4.51 7.40 2.58 8.72 1.78
## TMEM131 5.18 6.15 3.30 4.95 2.79 7.35 1.54
## FSCN1 126.18 125.48 91.20 100.11 89.54 132.02 49.92
## ACTB 2109.43 1761.17 1914.07 1868.02 2420.53 1965.70 2573.69
## MOCOS 25.93 38.67 39.55 38.19 24.10 41.02 14.66
## PLD1 3.81 2.32 2.79 1.66 2.20 1.81 1.55
## ATP12A 0.01 0.02 0.01 0.00 0.00 0.01 0.00
## WDR62 4.78 5.94 4.26 3.75 5.02 2.94 3.48
## DLG1 5.83 5.40 2.39 5.00 1.64 9.58 1.20
## RAB7A 160.39 184.81 112.31 177.92 83.70 283.10 45.41
## BCAP29 33.93 26.13 19.42 27.05 12.65 33.50 11.65
## SEC31B 1.36 1.31 1.23 1.14 0.91 1.64 1.75
## SART3 22.72 21.22 13.09 22.42 9.49 36.23 4.23
## ARHGAP15 0.23 0.32 0.44 0.20 0.13 0.05 0.29
## TUBA3D 0.10 0.05 0.00 0.07 0.01 0.09 0.00
## PAX2 0.19 0.12 0.21 0.17 0.12 0.15 0.12
## EXOSC7 46.87 41.26 43.80 42.68 40.90 42.08 26.88
## KIFAP3 30.84 35.42 29.49 29.97 19.78 26.07 12.21
## MKRN2 18.40 13.73 9.63 18.49 6.18 27.88 3.69
## MCM6 52.10 37.70 33.99 42.20 23.99 33.83 9.84
## REXO2 30.93 55.83 36.60 36.06 34.87 33.02 14.65
## RBM7 16.73 16.34 6.69 16.64 3.16 23.23 0.78
## RBMS2 2.24 1.88 1.65 1.44 1.29 1.80 0.99
## BAZ2A 12.69 10.44 6.82 11.33 5.70 19.02 9.50
## PTPN23 13.98 15.75 9.75 13.28 8.44 21.03 5.99
## MLH1 32.46 26.29 20.68 32.28 15.55 39.27 6.26
## UNG 79.77 52.40 38.30 40.96 28.98 30.73 12.82
## FMO4 3.37 3.23 1.70 3.26 0.99 2.26 0.19
## KLHL20 10.82 9.24 3.28 10.61 1.95 17.69 0.92
## RGS11 0.10 0.03 0.05 0.07 0.02 0.12 0.03
## SLC46A1 10.39 11.51 11.83 11.78 11.92 11.20 10.73
## PLXNA2 0.52 0.39 0.71 0.80 0.66 0.70 0.46
## SPAG5 12.21 15.40 8.22 6.47 5.42 5.45 2.19
## ANKRD13A 9.07 11.02 5.89 8.71 4.74 13.48 3.59
## TPD52 48.42 43.18 16.63 49.07 9.66 56.40 2.70
## ACACB 1.31 1.52 0.95 1.12 0.81 1.36 0.52
## TRAF4 53.54 56.43 41.51 56.41 36.79 72.71 23.51
## PAG1 0.83 0.65 0.17 0.33 0.15 0.77 0.11
## GPATCH1 6.18 5.73 4.15 5.48 3.82 6.78 2.75
## ICAM3 21.45 21.83 22.15 26.64 25.71 25.66 30.99
## NT5C2 26.83 20.65 12.25 28.93 7.48 51.70 3.99
## MCAM 70.69 67.57 40.71 41.93 33.26 33.04 16.48
## GPC4 1.65 1.76 1.11 1.86 0.61 2.70 0.25
## MBNL3 0.72 0.67 0.27 0.55 0.18 1.26 0.05
## CAMSAP3 0.06 0.03 0.03 0.01 0.02 0.06 0.06
## RAP1GAP 4.13 2.70 2.40 2.57 1.67 3.34 1.61
## XAB2 38.67 34.02 33.04 33.61 34.42 37.50 42.54
## ARHGEF1 140.53 135.10 127.26 105.16 143.74 83.03 100.85
## STXBP2 0.09 0.26 0.17 0.22 0.26 0.81 0.10
## MAP2K7 16.76 16.17 12.71 15.11 12.43 15.42 12.28
## NMRK2 0.00 0.04 0.03 0.07 0.00 0.05 0.00
## DGKD 14.04 9.14 6.53 8.61 5.25 12.63 4.10
## CTTNBP2 0.00 0.00 0.00 0.09 0.00 0.01 0.00
## ACTL6B 0.00 0.00 0.03 0.00 0.00 0.00 0.00
## RARB 0.39 0.36 0.18 0.32 0.07 0.30 0.04
## TOP2B 50.26 59.19 35.74 49.52 22.40 46.26 6.56
## TM9SF3 69.01 62.19 31.34 67.44 23.27 123.16 14.99
## NFKB2 67.43 42.78 43.33 55.86 32.69 63.41 20.79
## UBE2T 110.82 120.27 110.29 68.33 106.83 32.19 49.24
## PPP1R12B 1.90 1.94 0.97 1.80 1.17 2.52 0.56
## DNAJC10 24.47 16.50 10.42 27.68 5.50 41.70 3.37
## GTF3C1 46.73 65.18 52.23 46.45 50.62 42.97 43.94
## IL4R 4.79 4.09 2.72 2.36 2.52 2.42 1.87
## USP33 17.67 18.63 10.33 19.34 6.36 23.85 5.70
## PAK3 0.02 0.05 0.00 0.00 0.00 0.01 0.00
## CAPN6 0.00 0.00 0.01 0.00 0.00 0.01 0.00
## DCX 0.00 0.02 0.00 0.00 0.00 0.00 0.00
## SNRPA 71.16 104.00 84.02 58.40 95.61 40.25 78.11
## SPAG6 0.00 0.00 0.00 0.01 0.00 0.04 0.00
## EXOSC5 82.52 74.24 97.21 65.43 95.37 54.36 93.43
## DYNC1I2 15.25 13.39 7.84 13.01 7.06 17.15 11.42
## APBB1IP 0.00 0.00 0.00 0.00 0.00 0.02 0.00
## LRCH4 9.65 12.06 8.66 10.96 8.56 13.49 9.45
## FAM76B 11.55 9.17 3.07 10.74 1.13 18.49 0.58
## SIRT6 26.42 23.98 23.97 37.09 27.95 53.33 28.34
## TYR 0.00 0.00 0.02 0.00 0.00 0.00 0.00
## POLD3 19.59 16.66 10.83 13.84 9.56 12.77 3.93
## ACTN2 4.91 2.84 2.64 3.64 1.71 5.94 1.05
## CAPZB 136.05 136.51 108.03 134.18 87.00 153.94 50.21
## GPR137B 17.26 18.96 13.08 21.08 7.33 34.01 3.05
## NAALAD2 0.44 0.68 0.30 0.57 0.24 0.68 0.11
## JADE1 9.84 8.15 6.21 8.97 4.62 9.52 3.12
## SLC25A43 5.13 4.18 2.12 4.18 0.88 5.20 0.22
## UBE2A 57.73 53.62 34.36 64.08 27.50 78.54 15.34
## FGFR1 6.77 5.21 4.18 7.48 2.65 12.86 1.52
## FKBP6 0.00 0.03 0.00 0.02 0.08 0.04 0.00
## GTF2I 56.54 67.83 42.53 41.78 33.87 43.97 22.34
## SMC1B 0.00 0.02 0.00 0.00 0.01 0.02 0.01
## FBLN1 1.74 2.30 1.77 1.21 1.89 0.72 1.24
## ITGA8 0.01 0.01 0.01 0.00 0.00 0.00 0.00
## CST7 0.18 0.08 0.03 0.14 0.11 0.23 0.17
## MAP2 0.03 0.08 0.02 0.01 0.01 0.21 0.00
## PIAS2 10.71 9.57 6.29 8.51 4.38 11.79 2.96
## AMPH 0.02 0.07 0.04 0.01 0.00 0.01 0.00
## ARAF 43.41 48.73 51.87 39.51 61.10 36.08 84.29
## MCCC1 9.65 10.99 11.43 9.55 9.04 8.78 6.31
## LAMP3 0.72 0.20 0.29 0.74 0.12 1.59 0.10
## FAP 0.89 2.83 1.86 1.51 1.18 0.74 0.83
## NEBL 0.85 0.76 0.43 1.04 0.68 1.95 0.36
## ACER3 5.38 6.05 3.76 6.73 4.24 9.10 4.09
## UBE2K 47.34 52.86 46.85 47.86 43.10 49.53 32.55
## PIK3C3 41.33 39.60 32.13 43.27 23.88 46.64 17.46
## N4BP2 2.32 1.63 0.45 1.83 0.28 2.56 0.07
## C12orf5 15.69 17.40 11.39 16.99 7.17 26.34 2.42
## TULP3 14.34 13.07 8.63 13.68 7.43 23.49 3.57
## SYNJ2 10.74 7.58 5.78 6.22 5.16 6.12 2.93
## ADCY2 0.00 0.01 0.00 0.02 0.00 0.00 0.01
## PPP2R5C 46.83 44.96 34.18 48.33 31.13 53.35 29.06
## RBFOX1 0.00 0.02 0.01 0.00 0.00 0.00 0.00
## GNB1 184.42 161.04 117.70 165.73 85.03 219.16 49.47
## HOXA9 0.22 0.42 0.25 0.23 0.13 0.10 0.10
## EDN1 0.11 0.03 0.06 0.05 0.00 0.09 0.04
## MLLT10 8.20 7.01 2.89 6.44 1.64 8.96 0.51
## ZCWPW1 2.47 2.49 1.96 3.21 3.18 3.33 4.34
## ADCYAP1R1 0.04 0.02 0.01 0.07 0.02 0.04 0.00
## FGF20 0.00 0.00 0.00 0.03 0.00 0.00 0.00
## P2RY10 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## ITM2A 0.53 0.29 0.26 0.24 0.03 0.18 0.02
## NRD1 74.78 90.68 87.35 79.04 88.23 76.68 70.82
## VDAC3 70.45 79.29 60.66 69.39 46.12 64.41 21.02
## PCM1 37.77 37.70 37.16 37.82 29.58 36.98 25.90
## TNRC6C 2.59 2.32 1.57 3.03 1.50 4.68 1.19
## CBFA2T2 3.17 2.74 1.70 3.83 1.21 5.14 1.07
## BRINP1 0.00 0.03 0.00 0.00 0.01 0.00 0.00
## ITCH 16.44 12.14 5.71 13.08 3.40 23.89 2.25
## PKD2L2 0.06 0.07 0.07 0.07 0.03 0.21 0.03
## TP53INP2 2.54 2.91 1.66 2.18 1.40 3.39 0.95
## SDF4 89.48 106.81 84.14 93.14 72.34 94.51 50.27
## MYH7B 0.20 0.24 0.13 0.19 0.12 0.11 0.59
## BPIFB2 0.01 0.05 0.01 0.01 0.00 0.00 0.03
## TP73 5.97 6.65 4.68 2.47 4.72 1.63 2.59
## TOLLIP 13.79 13.69 11.15 16.72 12.51 26.91 8.91
## UBE2D4 12.11 12.00 11.05 12.01 8.99 14.23 7.38
## CLUL1 0.16 0.06 0.03 0.00 0.00 0.00 0.00
## RUNX1T1 0.67 0.32 0.27 0.40 0.19 0.88 0.22
## CDH17 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## THOC1 13.33 13.96 11.01 12.63 10.64 14.01 8.02
## FKBP7 7.29 12.87 8.71 10.36 5.71 11.27 1.94
## OSBPL6 5.93 4.89 3.56 7.64 3.33 9.58 2.21
## SLC1A3 1.87 1.77 1.38 0.67 0.53 1.12 1.19
## XRCC5 162.24 178.72 138.71 134.31 165.91 132.30 162.80
## LXN 0.09 0.02 0.04 0.12 0.02 0.08 0.18
## SP140 0.16 0.01 0.02 0.51 0.25 0.98 0.11
## MKNK1 16.27 18.00 14.09 16.28 11.61 22.29 10.03
## TNS1 0.12 0.17 0.08 0.06 0.06 0.13 0.04
## REXO1 12.09 12.15 8.41 11.54 4.58 15.71 2.31
## SAR1A 41.93 41.31 32.06 41.32 32.60 53.25 38.09
## CDC14A 2.36 1.80 0.58 1.53 0.32 2.36 0.07
## RAPGEF3 2.08 0.90 0.92 1.39 0.75 1.54 1.15
## CEACAM1 0.13 0.06 0.05 0.29 0.00 0.21 0.01
## SENP1 11.24 8.50 4.58 8.05 2.81 14.35 1.54
## DUSP13 0.00 0.04 0.00 0.00 0.03 0.00 0.10
## CIC 19.88 30.35 18.83 20.10 15.78 24.17 10.93
## LIPE 1.44 1.76 1.24 1.41 1.31 2.17 1.18
## FDFT1 44.44 56.98 43.25 51.37 32.73 57.05 24.72
## PAFAH1B3 24.38 36.70 39.38 21.83 49.78 18.61 42.72
## OPHN1 3.07 3.55 1.53 4.14 0.93 6.38 0.71
## AFM 0.02 0.00 0.00 0.00 0.02 0.00 0.07
## KIF22 61.66 60.24 66.24 51.65 77.45 41.37 80.88
## SCGN 0.00 0.04 0.00 0.00 0.02 0.00 0.00
## LRRC16A 0.92 1.29 0.88 1.17 0.72 1.03 0.33
## PGM1 23.27 42.14 26.62 19.21 25.24 17.50 13.38
## DDX1 93.99 96.65 62.09 82.25 44.77 82.78 16.63
## DNM2 75.48 78.23 55.66 76.47 51.61 93.72 36.98
## EPB41L2 29.69 19.52 11.56 28.98 8.74 38.75 7.35
## RIMS1 0.03 0.01 0.00 0.09 0.00 0.02 0.00
## MOXD1 0.57 1.25 0.63 0.71 0.53 0.61 0.26
## STX7 5.41 4.77 2.45 3.68 1.57 6.85 0.89
## RABL2B 11.50 10.58 8.12 10.90 6.10 13.27 4.19
## KEAP1 52.96 64.33 69.15 67.94 76.32 66.41 60.41
## DDX43 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PTPRH 5.31 2.98 2.44 5.28 1.32 7.96 1.00
## DCT 0.02 0.09 0.06 0.00 0.08 0.07 0.03
## SLC35C2 80.37 82.18 76.64 70.56 67.44 70.22 53.07
## CRYBG3 8.48 6.30 3.10 9.49 1.67 10.66 2.32
## EPHA6 0.21 0.15 0.17 0.20 0.05 0.22 0.05
## SCTR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RFX3 1.16 0.83 0.53 1.19 0.26 1.42 0.29
## RIF1 5.54 3.50 1.44 3.77 1.01 6.36 0.27
## RAB21 30.85 28.98 11.77 29.23 6.38 42.92 2.27
## SLC4A4 0.34 0.27 0.15 0.18 0.07 0.19 0.04
## SMARCA2 32.60 47.31 23.20 44.46 14.57 43.40 5.95
## RDH8 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SESN1 3.64 3.25 1.83 3.45 1.39 4.24 0.64
## MID2 0.86 0.64 0.38 1.04 0.33 1.34 0.15
## PIH1D3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## COL5A3 0.75 0.50 0.32 0.59 0.26 0.58 0.26
## SRCAP 15.84 14.33 10.25 11.86 10.33 18.53 8.23
## KIAA0020 144.38 148.38 156.71 134.01 166.66 112.51 181.50
## CPB2 0.05 0.11 0.01 0.10 0.01 0.05 0.01
## CHRNA3 0.10 0.21 0.10 0.15 0.10 0.24 0.09
## KCNN2 0.01 0.00 0.00 0.00 0.02 0.00 0.00
## CNOT4 5.81 6.41 3.87 6.52 3.27 10.55 2.90
## PSEN1 14.31 13.43 10.47 18.50 8.31 29.52 7.10
## CPOX 16.10 24.91 10.00 18.32 6.75 19.02 4.39
## CLDND1 66.50 56.10 38.97 52.07 25.65 65.48 11.46
## MOK 172.37 106.44 115.35 155.44 152.59 120.12 126.78
## HSP90AA1 557.70 616.91 401.90 487.81 334.33 616.51 364.39
## RBL1 8.00 5.33 3.25 6.48 3.37 8.27 3.41
## DLGAP4 29.05 27.25 17.11 22.43 18.23 32.47 25.69
## IGSF9B 0.85 0.73 0.25 0.79 0.29 1.23 0.32
## CFHR2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NDC80 10.07 11.18 9.18 6.36 7.29 3.66 3.26
## AP4E1 3.27 3.11 1.58 3.33 0.98 5.69 0.36
## RSBN1 2.77 3.42 1.37 2.61 0.91 5.61 0.48
## MAGI3 1.32 1.10 0.69 1.07 0.69 1.04 0.43
## CXCL2 4.29 3.38 3.11 2.79 1.74 2.36 0.50
## AFP 0.24 0.26 0.06 0.15 0.14 0.22 0.09
## COL4A4 0.04 0.04 0.02 0.06 0.01 0.13 0.01
## TCF7 0.71 1.20 0.53 0.72 0.55 1.40 0.48
## OSTM1 16.73 12.93 7.41 20.42 5.17 36.45 1.46
## CDH7 0.03 0.04 0.00 0.03 0.03 0.03 0.00
## IMPG2 0.03 0.03 0.02 0.03 0.01 0.07 0.00
## PCNP 104.94 105.18 52.41 108.73 36.74 133.34 21.33
## EXD2 3.70 3.12 2.09 3.12 1.17 4.76 0.48
## ARG2 5.21 6.12 4.39 4.34 3.81 5.73 1.97
## MEF2C 10.10 15.23 7.91 6.71 5.05 6.23 3.98
## PTPRC 0.00 0.04 0.01 0.06 0.00 0.08 0.01
## CACNA1S 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PKP1 0.00 0.00 0.00 0.00 0.00 0.03 0.00
## UBA5 22.59 27.23 15.42 26.20 12.09 30.92 12.18
## STK17B 0.85 1.07 0.52 1.07 0.33 1.73 0.04
## CDC14B 5.68 4.00 1.91 5.57 1.67 7.24 0.38
## ZNF510 3.34 2.80 1.40 3.39 1.46 5.53 0.98
## LRP2 0.01 0.18 0.09 0.05 0.02 0.06 0.00
## ZNF506 9.74 6.29 4.39 9.18 2.40 18.30 1.71
## JMJD4 27.20 29.86 28.01 19.94 26.79 16.74 22.94
## DUSP12 56.33 58.11 44.87 57.24 37.22 54.22 14.76
## AACS 12.27 12.32 9.51 13.72 9.02 19.61 4.69
## KIAA0141 57.37 51.75 39.87 50.38 32.83 40.82 21.65
## SLC13A1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CADPS2 2.02 2.05 1.39 1.29 1.00 1.03 0.69
## PCDHB4 0.15 0.14 0.06 0.23 0.04 0.23 0.00
## PCDHA6 2.70 2.13 1.06 1.82 0.63 2.36 0.07
## PCDHGA2 0.85 0.74 0.29 0.51 0.16 0.77 0.10
## HSPB11 80.35 101.31 86.64 87.14 90.17 70.73 45.21
## PHLPP1 2.56 2.36 1.49 1.69 1.56 1.57 0.85
## ATP8B1 0.07 0.13 0.06 0.01 0.05 0.09 0.00
## IL12RB2 0.04 0.02 0.02 0.09 0.01 0.05 0.00
## SMARCD3 20.34 26.93 22.66 22.31 20.17 24.48 14.51
## WDR70 31.21 34.93 42.67 28.75 50.61 23.79 60.43
## FYB 0.17 0.12 0.06 0.17 0.01 0.43 0.07
## MPP4 0.47 0.26 0.16 0.20 0.31 0.20 0.05
## STRADB 13.95 15.18 7.61 14.42 5.02 20.42 2.20
## BZW1 81.98 96.20 41.96 91.51 29.58 125.81 11.89
## PGR 0.00 0.01 0.01 0.00 0.00 0.00 0.00
## C1QTNF3 1.27 1.34 1.08 1.43 0.72 1.27 0.37
## ME2 18.42 18.88 9.37 16.69 5.10 23.19 0.65
## C5orf22 18.15 15.32 7.36 17.60 4.15 29.08 0.83
## CCNT2 2.80 2.82 1.02 3.63 0.70 8.01 0.23
## FAM135A 1.90 2.69 0.90 3.06 0.50 4.15 0.18
## COL19A1 9.12 9.37 6.05 7.09 5.76 8.23 3.31
## EPB41L3 0.02 0.12 0.01 0.19 0.11 0.28 0.01
## COBLL1 2.54 1.78 0.76 1.95 0.56 3.34 0.41
## DLG3 2.54 3.30 1.92 2.36 1.89 4.44 1.13
## KCNK2 0.46 0.29 0.19 0.44 0.08 0.47 0.04
## SERTAD4 34.26 40.93 24.80 28.94 23.26 24.74 9.29
## TRAF5 7.37 6.14 4.45 6.62 3.25 8.27 2.43
## MRPL22 59.49 59.21 63.35 58.01 59.28 57.32 46.34
## GEMIN5 10.38 8.67 4.63 7.07 2.83 9.35 0.98
## OPRK1 0.00 0.00 0.01 0.01 0.00 0.02 0.00
## NFE2L1 60.66 52.78 38.37 72.99 34.96 134.55 30.06
## SEMA5B 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## GSK3B 30.88 43.79 40.21 21.33 39.77 19.39 38.74
## ITGB5 31.43 40.54 30.46 33.61 36.58 34.06 19.38
## ERC1 5.58 5.03 2.92 4.05 2.36 6.51 1.19
## XPO1 51.81 64.00 33.00 58.99 22.09 75.03 9.34
## C4orf6 0.06 0.22 0.22 0.19 0.13 0.14 0.10
## RNF13 23.48 24.30 10.67 30.90 4.75 38.41 1.41
## TRPM3 0.77 1.59 0.72 0.79 1.17 0.43 0.71
## PALB2 10.56 14.68 5.73 11.69 4.79 10.53 1.44
## DOPEY1 1.26 1.26 0.65 1.17 0.31 1.92 0.09
## LYRM2 31.93 27.49 18.23 23.86 12.58 23.97 8.11
## BCKDHB 5.12 5.88 3.85 5.13 1.64 5.72 0.55
## mRNA_R10 mRNA_R14 mRNA_R13 mRNA_R12 mRNA_R11 mRNA_R9 mRNA_R8
## TSPAN6 6.22 7.73 5.59 7.72 8.73 7.69 7.28
## TNMD 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DPM1 98.06 81.59 100.83 86.01 87.73 75.97 96.31
## SCYL3 4.46 5.01 5.81 6.16 2.24 5.24 3.83
## C1orf112 8.48 14.43 10.52 7.09 1.85 7.89 3.84
## FGR 0.07 0.04 0.11 0.02 0.04 0.09 0.07
## CFH 2.11 1.44 1.55 1.72 1.66 1.60 1.54
## FUCA2 43.07 57.62 44.18 63.00 33.95 64.32 65.58
## GCLC 63.92 90.15 89.25 265.87 60.18 305.94 266.07
## NFYA 16.31 30.61 16.38 20.30 14.24 24.09 15.30
## STPG1 0.59 0.24 0.54 0.25 0.06 0.07 0.45
## NIPAL3 16.29 10.71 14.88 15.64 11.09 10.70 10.90
## LAS1L 46.29 50.00 44.09 39.82 38.82 51.57 40.59
## ENPP4 0.09 0.05 0.06 0.02 0.07 0.02 0.00
## SEMA3F 9.87 7.60 10.85 10.21 17.08 9.74 8.97
## CFTR 0.01 0.02 0.01 0.00 0.00 0.02 0.00
## ANKIB1 48.06 50.32 49.88 40.26 26.32 47.80 30.31
## CYP51A1 22.60 26.48 24.97 23.99 20.85 21.53 26.24
## KRIT1 52.60 56.49 51.33 49.83 28.54 56.94 36.27
## RAD52 8.69 9.22 8.33 9.20 8.89 9.70 8.35
## BAD 125.51 129.00 126.85 103.50 75.19 100.02 106.38
## LAP3 40.25 39.71 33.01 34.33 35.27 38.16 37.19
## CD99 440.12 405.17 430.73 547.68 486.60 491.22 662.88
## HS3ST1 0.22 0.12 0.12 0.19 0.02 0.15 0.16
## AOC1 0.11 0.03 0.00 0.11 0.07 0.15 0.14
## WNT16 0.00 0.00 0.00 0.04 0.00 0.00 0.00
## HECW1 7.85 14.11 7.94 18.45 8.55 17.73 21.56
## MAD1L1 63.79 44.45 61.92 58.98 122.75 47.59 67.01
## LASP1 176.35 131.92 198.94 136.66 105.47 118.47 109.97
## SNX11 14.76 14.17 13.21 14.16 13.16 12.36 11.69
## TMEM176A 0.23 0.07 0.10 0.00 0.09 0.05 0.00
## M6PR 64.36 71.38 58.92 73.49 69.49 72.71 74.86
## KLHL13 0.00 0.00 0.00 0.03 0.00 0.01 0.00
## CYP26B1 3.19 7.38 3.34 4.13 2.11 13.79 3.25
## ICA1 0.00 0.00 0.07 0.00 0.16 0.00 0.00
## DBNDD1 10.62 10.21 8.89 3.66 2.33 5.11 2.09
## ALS2 7.98 8.35 7.08 8.41 7.30 8.51 8.06
## CASP10 0.28 0.32 0.25 0.43 0.55 0.56 0.31
## CFLAR 19.26 18.49 19.64 18.04 23.37 21.37 17.78
## TFPI 128.91 65.10 124.32 142.97 142.38 119.61 140.79
## NDUFAF7 13.16 13.77 13.16 13.21 8.44 14.35 13.19
## RBM5 44.83 54.96 47.11 47.27 33.56 66.83 42.86
## MTMR7 1.29 1.22 1.45 1.84 0.59 1.44 2.42
## SLC7A2 3.33 3.78 4.17 4.95 5.06 5.39 3.79
## ARF5 195.68 152.06 175.96 181.75 276.53 166.99 200.95
## SARM1 11.61 17.91 13.42 14.87 11.66 19.41 10.63
## POLDIP2 108.58 117.40 104.47 112.66 101.51 106.78 104.00
## PLXND1 122.79 119.65 113.58 122.54 99.19 134.15 109.29
## AK2 193.01 180.79 203.49 163.38 166.32 168.84 148.66
## CD38 0.05 0.00 0.02 0.00 0.02 0.01 0.00
## FKBP4 69.99 118.48 96.26 71.58 94.76 84.32 76.60
## KDM1A 62.49 63.25 59.16 47.47 36.66 56.41 38.53
## RBM6 24.18 32.05 23.43 21.91 21.76 29.44 20.76
## CAMKK1 7.00 7.19 10.31 16.48 11.90 15.70 15.92
## RECQL 47.18 55.15 60.04 42.15 20.54 38.04 25.86
## CCDC132 17.11 20.14 16.01 18.64 12.22 18.78 14.50
## HSPB6 0.37 0.93 0.39 0.46 0.51 0.47 0.46
## ARHGAP33 12.48 14.40 13.56 15.05 8.32 15.38 8.49
## NDUFAB1 171.06 221.85 185.10 178.28 195.92 174.62 198.90
## PDK4 0.90 4.18 1.34 0.48 0.08 0.95 0.07
## SLC22A16 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZMYND10 6.09 3.20 5.31 3.28 2.60 3.85 2.85
## ABCB5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ARX 0.01 0.00 0.00 0.00 0.02 0.00 0.01
## SLC25A13 20.13 32.95 23.42 29.05 19.75 30.66 24.90
## ST7 11.05 15.68 13.42 14.15 8.22 11.87 12.82
## CDC27 50.81 66.21 58.70 57.04 31.67 62.88 36.63
## SLC4A1 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## CALCR 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## HCCS 26.54 30.74 25.28 20.81 25.99 20.54 18.29
## DVL2 44.27 41.69 43.90 45.35 45.50 45.64 44.86
## PRSS22 0.00 0.00 0.00 0.04 0.00 0.00 0.06
## UPF1 36.06 35.19 33.18 25.95 26.22 29.04 21.63
## SKAP2 9.30 9.65 12.08 11.58 10.33 8.98 8.10
## SLC25A5 347.29 525.52 442.05 338.18 316.49 337.16 288.43
## CCDC109B 7.84 7.05 7.44 5.56 11.75 4.69 4.42
## HOXA11 0.11 0.13 0.15 0.03 0.09 0.14 0.03
## POLR2J 141.37 175.39 144.23 124.00 120.58 120.76 157.11
## DHX33 11.53 15.62 11.81 10.78 5.87 12.96 7.81
## MEOX1 0.07 0.03 0.02 0.02 0.00 0.02 0.00
## THSD7A 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## LIG3 7.86 8.71 6.52 7.85 18.23 8.83 5.36
## RPAP3 22.50 29.68 24.18 23.04 16.87 22.35 24.68
## ACSM3 1.35 0.76 0.85 0.78 1.15 1.26 1.79
## AC004381.6 9.72 8.50 8.82 7.42 10.20 8.18 3.37
## CIAPIN1 56.62 64.98 59.56 56.27 51.29 61.89 52.80
## FAM214B 16.04 14.70 15.47 22.47 16.28 16.60 22.50
## COPZ2 94.89 71.09 72.48 101.24 120.31 86.87 84.95
## PRKAR2B 13.40 22.50 10.22 7.30 3.72 12.50 5.28
## MSL3 14.84 21.45 16.60 13.18 7.94 16.18 12.62
## CREBBP 11.09 15.93 12.62 9.99 5.87 15.55 7.78
## BZRAP1 0.04 0.10 0.14 0.07 0.00 0.18 0.05
## MPO 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PON1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GCFC2 12.32 12.06 11.28 10.12 8.25 9.89 10.33
## WDR54 62.43 46.43 59.11 45.58 33.97 46.27 34.08
## CROT 24.45 42.25 22.95 27.30 13.57 33.27 21.44
## ABCB4 0.00 0.00 0.00 0.12 0.03 0.08 0.20
## KMT2E 14.16 11.25 16.11 13.92 11.95 15.56 9.45
## RHBDD2 88.85 106.15 95.14 90.84 102.05 88.87 87.58
## SOX8 0.00 0.00 0.00 0.00 0.05 0.00 0.00
## IBTK 13.14 11.70 13.89 13.81 14.28 13.58 14.85
## ZNF195 8.62 13.87 9.63 10.18 6.32 12.60 8.47
## MYCBP2 11.61 17.96 10.65 11.51 3.19 14.14 8.51
## FBXL3 25.66 33.37 31.14 27.09 16.44 26.84 21.71
## ITGAL 0.09 0.12 0.08 0.01 0.13 0.11 0.01
## PDK2 35.46 36.27 27.64 40.23 38.94 40.23 38.31
## ITGA3 267.78 130.58 246.94 210.22 206.82 166.11 165.26
## ZFX 7.95 9.96 10.69 10.55 4.13 11.04 8.24
## LAMP2 109.42 87.33 104.45 149.65 101.09 128.33 141.06
## GGNBP2 54.92 46.77 52.30 43.23 40.25 47.14 44.53
## ITGA2B 0.29 1.05 0.19 0.03 0.23 0.38 0.27
## ASB4 0.00 0.00 0.08 0.02 0.00 0.00 0.00
## GDE1 54.13 69.91 57.80 52.60 46.92 54.09 41.17
## C19orf60 37.18 39.05 26.62 63.33 46.99 54.31 79.95
## CRLF1 46.29 41.71 46.80 54.07 43.20 45.81 41.30
## OSBPL7 10.24 8.25 9.51 11.52 11.65 13.96 10.88
## TMEM98 0.07 0.26 0.18 0.17 0.10 0.04 0.10
## YBX2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## KRT33A 0.03 0.09 0.03 0.00 0.00 0.02 0.02
## ABCC8 0.95 0.63 0.77 0.26 0.60 0.64 0.74
## CCL18 0.00 0.00 0.00 0.00 0.34 0.00 0.09
## CCL3 0.06 0.00 0.05 0.00 0.04 0.04 0.00
## SYNRG 14.25 13.22 12.17 13.70 11.89 12.98 10.48
## CACNG3 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## TMEM132A 87.95 108.76 100.38 79.00 59.83 108.62 67.13
## AP2B1 112.03 92.22 100.81 102.06 114.66 99.35 80.52
## TAC1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZNF263 24.55 20.87 27.43 24.53 20.33 25.68 18.79
## CX3CL1 1.61 3.95 2.67 2.00 0.91 4.89 1.03
## SPATA20 60.85 62.17 49.36 66.60 87.50 87.00 54.70
## CACNA1G 0.45 1.42 0.52 1.32 0.42 1.76 0.82
## TNFRSF12A 269.92 189.51 307.13 199.29 132.04 107.83 153.61
## DLX6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MAP3K9 0.69 0.77 0.78 0.51 0.32 0.62 0.33
## RALA 50.64 41.95 51.34 61.99 62.53 40.94 73.41
## BAIAP2L1 9.18 5.05 8.86 7.25 11.15 6.47 6.91
## KDM7A 1.23 1.49 1.65 2.10 1.46 1.38 1.63
## ETV1 0.23 0.15 0.30 0.11 0.48 0.06 0.04
## AGK 27.38 24.63 25.49 23.97 22.21 25.06 19.12
## ALDH3B1 45.09 16.35 32.98 47.01 65.27 35.15 43.00
## TTC22 0.00 0.00 0.00 0.00 0.00 0.01 0.01
## PHTF2 19.66 31.34 23.80 23.68 11.80 24.79 21.97
## CCL26 4.39 17.87 8.72 5.65 5.71 4.24 8.27
## FARP2 12.04 10.50 14.10 15.82 4.09 15.07 5.67
## USH1C 0.00 0.04 0.10 0.00 0.16 0.00 0.00
## GGCT 68.05 82.63 82.40 54.64 51.74 49.20 52.84
## DBF4 26.49 40.02 32.31 23.43 12.36 25.65 18.34
## TBXA2R 0.15 0.09 0.10 0.17 0.08 0.10 0.16
## IFRD1 29.86 32.12 33.99 34.13 46.70 30.99 40.01
## LGALS14 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## COX10 11.34 12.46 12.09 13.27 11.42 13.71 10.47
## GTF2IRD1 36.47 36.01 43.31 35.95 27.87 32.72 31.11
## PAF1 32.33 44.23 33.31 28.52 30.91 33.01 28.66
## VPS41 24.47 26.25 25.01 28.41 31.56 26.84 22.28
## ARHGAP44 0.02 0.06 0.01 0.06 0.06 0.04 0.03
## ELAC2 41.45 60.97 47.67 47.92 40.81 55.74 44.77
## SCIN 0.00 0.00 0.00 0.00 0.01 0.05 0.01
## ARSD 15.83 12.00 11.61 11.82 12.10 14.47 10.28
## PNPLA4 0.00 0.00 0.26 0.00 0.00 0.00 0.00
## MYH13 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ADIPOR2 31.33 34.77 32.65 32.98 19.75 29.61 28.10
## CDKL3 5.89 3.38 4.78 7.46 6.99 4.60 8.84
## UPP2 0.00 0.00 0.00 0.02 0.00 0.00 0.00
## PRSS21 0.07 0.00 0.00 0.00 0.00 0.00 0.00
## MARK4 33.91 25.94 29.88 25.07 27.53 28.50 21.86
## PROM1 0.11 0.14 0.02 0.06 0.29 0.11 0.00
## CCDC124 90.54 105.94 92.30 79.22 72.16 77.11 78.67
## CEACAM21 0.03 0.00 0.00 0.00 0.00 0.00 0.06
## PAFAH1B1 76.24 77.64 82.06 68.52 80.02 65.37 60.00
## NOS2 0.02 0.03 0.01 0.01 0.01 0.02 0.01
## DNAH9 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## KIAA0100 35.41 50.62 34.79 32.65 19.87 44.03 21.88
## SLC13A2 0.00 0.00 0.00 0.00 0.04 0.00 0.00
## GAS7 0.47 0.66 0.21 0.23 0.59 0.16 0.08
## TRAPPC6A 65.78 41.27 40.85 64.29 92.78 55.78 68.01
## MATK 0.02 0.00 0.00 0.11 1.56 0.06 0.09
## CEACAM7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CD79B 0.00 0.00 0.00 0.00 0.24 0.00 0.00
## SCN4A 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## ST7L 19.32 16.76 16.99 19.01 21.88 18.20 16.13
## TKTL1 0.00 0.03 0.00 0.00 0.04 0.00 0.00
## PAX6 2.20 1.84 2.07 2.00 1.13 1.53 1.77
## RPUSD1 22.63 38.83 31.38 26.10 13.04 28.08 23.33
## RHBDF1 33.80 29.99 27.29 31.45 34.12 36.86 35.47
## LUC7L 24.76 43.57 31.82 25.82 18.66 37.92 25.32
## CACNA2D2 0.39 0.30 0.64 0.34 0.06 0.33 0.15
## BAIAP3 0.45 0.25 0.54 0.62 0.11 0.29 0.13
## TSR3 86.49 78.71 79.69 75.02 110.53 79.74 80.64
## PIGQ 41.31 53.39 39.02 32.35 30.11 39.99 27.21
## CRAMP1L 8.17 11.97 9.84 8.63 4.97 10.27 6.60
## TEAD3 13.91 12.97 13.66 14.98 9.87 15.25 14.66
## SELE 0.00 0.02 0.00 0.00 0.02 0.00 0.00
## DNAJC11 26.69 34.65 28.53 24.54 18.27 31.92 21.01
## FMO3 0.80 0.10 0.18 0.07 0.20 0.11 0.08
## MYLIP 11.23 12.71 15.23 14.02 15.51 18.19 10.30
## NOX1 0.02 0.07 0.05 0.16 0.00 0.03 0.05
## E2F2 3.17 6.29 4.35 1.25 0.24 1.65 0.40
## PSMB1 298.84 292.85 274.44 408.11 337.93 314.67 480.34
## SYN1 0.58 0.60 0.48 0.56 0.75 0.48 0.23
## JARID2 9.16 6.98 10.28 17.60 17.10 13.65 17.02
## CDKL5 0.58 0.45 0.36 0.19 0.09 0.19 0.07
## CAMK1G 0.55 0.59 0.67 0.20 1.23 0.20 0.13
## CDK11A 26.08 36.29 28.08 25.98 23.33 29.96 24.61
## NADK 34.72 48.12 31.74 33.40 25.01 47.09 32.48
## TFAP2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TFAP2D 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DLEC1 0.03 0.09 0.05 0.01 0.08 0.05 0.06
## CYTH3 15.30 13.01 14.71 13.49 10.03 12.70 10.47
## ADAM22 3.13 3.20 1.68 2.25 1.58 2.81 1.54
## SYPL1 64.78 70.85 70.73 61.90 63.25 61.62 73.16
## CYB561 66.81 66.12 65.93 44.85 37.06 59.27 34.19
## SPAG9 43.35 26.79 44.61 36.39 32.17 32.62 33.04
## CELSR3 17.43 16.25 16.15 16.07 11.45 22.11 13.11
## AASS 6.59 7.24 5.29 5.92 4.27 9.38 5.02
## PLEKHG6 0.35 0.60 0.70 1.17 0.25 1.84 1.01
## SS18L2 23.06 26.77 24.47 23.73 17.82 21.28 24.96
## MPND 16.98 17.27 14.84 13.12 22.28 15.12 12.10
## MGST1 461.34 512.71 401.56 749.13 338.68 742.32 1191.50
## CRY1 7.40 10.99 9.74 7.74 6.07 7.23 6.27
## PGLYRP1 0.00 0.00 0.06 0.00 0.00 0.04 0.09
## NFIX 85.18 93.32 86.09 85.79 77.05 105.90 49.17
## ST3GAL1 38.11 91.83 53.95 53.85 28.02 93.64 31.11
## MMP25 1.20 1.37 0.93 2.19 0.82 3.13 1.51
## IL32 64.49 13.92 31.76 23.06 61.68 14.01 16.40
## PKD1 58.55 53.55 59.20 52.52 41.95 65.42 40.56
## MAPK8IP2 0.50 1.13 0.63 2.10 2.49 2.39 3.00
## MED24 54.42 52.02 50.53 43.88 57.22 54.81 36.61
## RHOBTB2 6.71 11.10 7.67 8.02 4.31 7.21 5.27
## HEATR5B 4.05 4.02 3.74 4.38 2.11 4.86 3.38
## SEC62 96.35 105.59 106.06 104.98 93.45 102.72 132.35
## RPS20 2194.40 2060.24 2063.85 2023.89 2709.44 1555.23 2093.98
## CSDE1 283.84 298.27 296.41 247.67 227.33 264.25 210.06
## UBE3C 37.23 53.01 42.75 35.56 30.67 40.84 27.12
## REV3L 9.07 5.86 5.79 6.26 10.61 8.97 6.71
## TENM1 0.01 0.02 0.01 0.00 0.01 0.01 0.00
## PAX7 0.01 0.01 0.00 0.00 0.03 0.01 0.00
## MASP2 0.84 0.59 1.14 0.55 0.15 0.71 0.33
## IYD 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## FAM76A 4.42 6.12 5.64 6.11 5.55 5.55 5.63
## TRAF3IP3 3.07 3.46 3.86 2.24 2.24 2.42 2.27
## POMT2 4.09 7.12 5.56 6.45 10.91 6.50 8.01
## VTA1 30.67 35.82 33.52 30.35 19.90 28.78 26.27
## MLXIPL 0.13 0.10 0.06 0.09 0.24 0.16 0.00
## BAZ1B 34.52 50.18 35.73 30.73 11.27 34.25 22.91
## RANBP9 37.60 46.19 49.31 39.40 23.12 38.40 36.13
## ETV7 2.03 1.98 1.42 0.33 1.44 0.89 0.38
## SPRTN 5.69 8.16 6.21 6.04 3.25 6.35 6.64
## METTL13 15.57 22.47 14.43 18.82 18.48 21.15 17.36
## DYRK4 32.77 26.73 30.38 19.42 43.82 27.20 22.39
## ZNF207 182.34 166.84 180.69 173.96 164.50 170.07 134.32
## UQCRC1 245.38 253.08 240.66 216.56 213.37 221.87 213.16
## STARD3NL 74.59 67.55 74.27 82.58 89.17 71.28 99.10
## CD9 108.93 99.74 126.78 82.10 140.77 75.12 66.56
## HHATL 0.00 0.00 0.00 0.00 0.00 0.00 0.08
## NCAPD2 35.92 58.12 44.51 28.15 22.21 41.51 18.68
## IFFO1 12.14 17.59 11.17 10.24 10.19 16.45 10.09
## GIPR 1.81 2.20 1.91 1.82 3.12 3.21 2.32
## PHF7 12.83 7.51 13.36 14.47 12.40 15.89 10.97
## SEMA3G 0.14 0.24 0.31 0.10 0.04 0.18 0.11
## NISCH 31.63 31.04 27.62 30.16 32.62 41.71 22.67
## STAB1 0.02 0.10 0.01 0.05 0.01 0.02 0.02
## FUZ 19.99 27.32 17.31 12.94 18.93 19.26 10.79
## SLC6A13 0.00 0.11 0.21 0.07 0.07 0.00 0.00
## IDS 88.21 65.19 91.88 87.70 71.82 75.60 63.51
## PRSS3 0.00 0.00 0.00 0.07 0.04 0.00 0.00
## ZNF200 6.18 4.51 5.64 6.14 5.24 6.01 4.92
## CD4 0.73 0.31 0.34 0.36 0.56 0.50 0.25
## LRRC23 29.79 23.91 27.45 29.23 36.59 25.32 28.19
## BTK 0.00 0.00 0.00 0.00 0.00 0.03 0.06
## HFE 9.97 14.29 8.44 18.42 6.60 19.17 13.92
## SCMH1 25.53 27.27 28.88 23.68 17.05 25.82 17.82
## FYN 7.99 4.74 7.16 4.33 9.62 5.82 6.35
## HIVEP2 4.33 4.11 4.24 2.70 2.84 2.84 1.91
## FMO1 0.32 0.07 0.18 0.12 0.72 0.04 0.06
## TCEB3 24.68 22.29 24.87 23.67 17.80 22.65 20.17
## LYPLA2 54.10 63.87 52.80 58.42 43.08 53.82 50.64
## CLCN6 8.34 5.78 7.69 8.67 10.83 8.86 7.63
## MRC2 318.74 258.64 257.38 245.66 194.43 311.08 185.82
## NME2 495.49 630.67 549.58 492.47 623.87 558.41 627.07
## SLC6A7 0.01 0.00 0.00 0.00 0.00 0.01 0.00
## TSPAN9 6.52 5.07 4.74 9.37 7.39 7.88 7.98
## BTBD7 7.09 5.99 6.14 6.09 3.18 5.33 4.33
## APBA3 14.04 13.35 13.61 9.97 7.15 10.96 8.84
## MKS1 15.87 13.61 11.89 13.75 17.73 16.15 11.64
## ABHD5 10.68 16.09 13.56 12.41 10.73 10.42 11.18
## KAL1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## AKAP8L 45.37 46.15 48.19 45.64 34.32 49.62 48.11
## MBTD1 4.73 4.53 5.45 5.68 2.85 6.41 4.95
## UTP18 44.67 58.50 55.87 51.59 32.37 55.58 51.44
## RNF216 31.82 36.26 35.89 27.47 18.70 34.81 24.22
## TTC19 40.15 38.52 37.55 32.38 45.00 37.71 28.31
## PTBP1 162.04 191.21 191.51 142.38 82.98 178.95 114.64
## DPF1 1.84 5.31 2.88 1.70 1.19 1.94 1.06
## SYT7 0.32 0.33 0.72 0.57 2.17 0.19 0.15
## LARS2 7.89 10.76 7.97 8.01 4.52 9.25 6.43
## PIK3C2A 8.12 12.53 10.22 10.16 4.82 9.86 7.87
## PLAUR 65.42 25.09 57.71 62.21 51.80 35.76 54.19
## ANLN 52.96 83.08 72.28 28.00 13.18 36.66 10.97
## WIZ 20.22 26.53 23.01 19.57 16.90 25.50 15.03
## RABGAP1 14.56 16.83 13.68 14.39 7.57 15.99 12.21
## DCN 0.46 0.47 0.62 0.53 0.28 0.58 0.24
## QPCTL 21.34 13.85 18.60 22.08 22.13 21.32 23.74
## PPP5C 38.04 56.45 46.24 39.16 30.38 40.55 33.29
## CEP68 5.95 6.48 4.56 6.90 6.41 8.34 6.46
## MAP4K3 9.70 9.38 9.33 9.25 6.12 9.54 10.17
## ZBTB32 0.17 0.02 0.02 0.10 0.23 0.09 0.16
## TYROBP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMEM159 17.18 7.78 18.13 18.40 21.50 10.81 16.31
## GABRA3 3.77 4.79 3.17 3.66 0.97 4.63 2.08
## BRCA1 15.67 25.58 17.52 9.54 3.59 11.91 5.17
## ERCC1 94.23 84.27 86.50 78.83 107.81 78.23 69.25
## CD22 1.58 2.40 2.63 6.95 4.39 4.75 8.16
## MBTPS2 15.90 19.71 17.21 17.89 14.09 19.36 15.60
## PRICKLE3 6.33 6.84 6.64 8.19 7.08 9.00 6.93
## LTF 0.00 0.00 0.08 0.07 0.16 0.00 0.00
## EXTL3 13.84 16.68 13.69 14.52 7.05 16.97 10.58
## NR1H4 0.00 0.05 0.00 0.00 0.07 0.02 0.00
## ELOVL5 101.28 110.04 112.46 104.40 76.24 97.93 112.73
## ALOX5 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## KDM5D 6.12 10.96 5.86 6.25 6.42 11.22 4.83
## CALCOCO1 53.66 51.72 42.21 66.28 35.49 76.00 52.30
## UBR7 17.16 24.31 20.69 13.16 9.68 12.68 9.77
## MAP4K5 11.47 9.88 12.82 10.39 4.45 9.02 9.72
## EHD3 3.68 4.95 3.50 2.19 1.12 3.18 1.66
## PSMC4 99.28 121.14 107.59 141.05 87.51 114.56 194.45
## MAN2B2 23.52 20.63 20.02 24.49 18.25 25.74 19.56
## SLC7A14 0.00 0.01 0.00 0.00 0.00 0.01 0.00
## CLDN11 3.42 3.34 2.07 1.63 1.93 2.89 1.00
## SLC25A39 118.17 131.91 111.76 104.60 112.82 107.10 95.02
## MVP 279.05 221.02 227.15 224.03 203.96 263.49 204.26
## NUB1 97.12 80.55 78.15 61.73 74.89 67.15 56.18
## PGM3 36.21 14.19 36.97 19.14 27.67 15.09 12.28
## RWDD2A 9.34 6.80 7.81 9.74 6.96 8.47 8.99
## CLK1 27.11 25.25 30.87 29.71 27.50 44.30 35.59
## POLR3B 2.49 5.05 3.38 2.76 1.59 3.54 2.60
## ANGEL1 4.95 5.59 4.24 4.79 4.15 6.57 3.87
## RNF14 32.99 43.20 34.75 50.28 67.06 42.75 52.57
## DNASE1L1 44.45 31.80 36.43 39.44 48.85 36.71 32.14
## DDX11 25.30 33.64 26.66 21.52 12.36 28.32 17.09
## HEBP1 86.80 72.06 82.76 119.72 106.94 102.11 162.00
## GPRC5A 48.42 9.72 24.38 21.33 47.21 11.96 26.95
## MAMLD1 4.32 2.84 5.66 2.38 1.76 1.99 1.82
## CD6 0.01 0.00 0.01 0.00 0.00 0.00 0.10
## TACC3 25.51 46.73 31.66 17.29 14.11 27.31 11.69
## UFL1 17.79 10.87 16.44 18.02 16.08 15.30 18.28
## POLA2 33.26 49.75 39.40 16.47 10.04 21.98 12.89
## ZC3H3 15.66 14.07 16.11 14.34 14.14 16.73 13.84
## CAPN1 109.11 113.38 103.51 100.44 82.36 112.37 87.56
## ACPP 0.58 0.61 0.72 0.52 0.32 0.54 0.51
## MDH1 164.94 187.38 165.22 183.62 191.87 178.31 207.19
## SLC30A9 30.41 33.45 33.21 31.53 23.58 30.57 28.49
## MTMR11 16.40 12.36 16.27 14.50 9.65 14.35 11.42
## COX15 24.00 28.86 23.57 30.50 26.85 31.98 25.49
## CCDC88C 0.83 1.05 0.36 0.52 0.49 0.31 0.22
## YAF2 15.45 16.74 12.41 10.33 9.66 12.55 14.90
## ZMYND11 22.27 22.66 23.09 19.78 15.50 21.25 22.96
## WAS 0.13 0.16 0.06 0.09 0.11 0.22 0.20
## DPEP1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## BID 97.10 80.86 104.04 78.91 77.76 73.07 79.41
## MATR3 227.35 251.87 254.83 232.84 152.57 222.67 222.36
## NPC1L1 0.04 0.05 0.10 0.04 0.09 0.12 0.03
## XYLT2 34.60 25.10 27.87 27.78 28.30 32.27 25.18
## RGPD5 1.92 1.41 1.97 1.45 1.86 2.94 1.37
## STMN4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NUDCD3 58.72 48.85 45.44 39.25 53.31 41.64 37.42
## ISL1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CHDH 0.03 0.07 0.04 0.01 0.00 0.00 0.01
## IL20RA 0.00 0.00 0.04 0.00 0.00 0.00 0.00
## CLCA1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CLCA4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GLT8D1 107.81 68.22 99.73 100.04 93.55 95.66 81.92
## ATP2C1 50.35 50.07 52.49 47.65 26.50 45.70 40.63
## SRCIN1 0.08 0.15 0.18 0.08 0.13 0.06 0.15
## IGF1 0.01 0.00 0.00 0.00 0.13 0.00 0.00
## SLC38A5 0.36 0.36 0.92 0.14 0.16 0.40 0.08
## MAGIX 0.81 1.33 0.58 1.11 1.36 1.23 1.29
## RALBP1 23.35 27.44 23.82 21.31 15.86 21.57 19.96
## RUFY3 11.19 10.83 11.92 17.92 9.69 17.94 18.17
## CNTN1 0.02 0.00 0.11 0.00 0.00 0.00 0.00
## SLC11A1 0.19 0.07 0.16 0.22 0.31 0.20 0.20
## WWTR1 63.35 72.94 59.80 66.09 32.07 72.81 51.43
## AGPS 27.45 32.46 29.33 20.01 12.58 21.39 14.83
## CXorf56 24.96 25.50 22.41 24.80 32.57 26.22 25.75
## ATP1A2 0.02 0.00 0.04 0.02 0.09 0.10 0.01
## TTC27 5.32 5.15 5.92 3.34 4.98 4.56 2.47
## ZNF582 0.47 0.36 0.33 0.26 1.34 0.36 0.29
## VSIG2 0.00 0.29 0.06 0.00 0.00 0.02 0.00
## PHLDB1 25.77 29.27 23.55 21.32 12.63 25.29 14.18
## MARCO 0.00 0.00 0.00 0.00 0.04 0.00 0.00
## CYP24A1 0.08 0.00 0.08 0.00 0.00 0.00 0.00
## PRDM11 2.05 4.25 2.20 2.29 1.50 2.69 1.76
## SYT13 0.01 0.03 0.08 0.04 0.04 0.01 0.01
## SNAI2 29.89 55.84 47.43 115.66 22.24 103.26 153.61
## CD74 55.35 24.31 32.99 35.13 84.13 39.80 35.25
## HGF 0.04 0.07 0.01 0.00 0.00 0.00 0.01
## ZRANB1 9.83 10.31 11.53 8.64 4.93 9.22 7.48
## NCDN 23.02 25.61 22.62 42.44 25.90 40.93 34.04
## GPR124 21.56 16.50 14.77 8.13 8.55 13.75 4.31
## ZFP64 12.14 12.78 11.62 11.76 8.53 13.60 10.28
## MNAT1 39.90 32.99 35.64 24.63 29.17 24.15 24.58
## SAMD4A 3.62 1.48 2.82 0.94 2.27 1.06 0.67
## RUNX3 0.87 0.79 0.86 0.36 1.14 0.49 0.39
## MRE11A 14.00 21.56 16.07 12.09 4.42 14.96 6.73
## PLEKHB1 0.44 0.62 0.34 0.09 0.15 0.49 0.42
## SERPINB1 0.01 0.05 0.09 0.00 0.00 0.03 0.08
## CYP3A43 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SLC7A9 0.11 0.08 0.19 0.00 0.04 0.03 0.06
## SPAST 3.11 4.89 4.18 4.41 2.98 5.05 4.95
## NRXN3 0.16 0.21 0.50 0.18 0.03 0.21 0.17
## OSBPL5 26.10 16.16 25.63 19.20 15.55 22.97 15.03
## AQR 13.99 12.73 11.67 13.38 11.30 15.53 14.08
## CPS1 12.09 14.03 9.91 9.25 3.79 12.13 6.16
## C8B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## FHL1 79.48 85.72 81.55 59.17 42.86 70.92 48.13
## RTFDC1 183.23 171.98 177.09 148.02 204.31 142.93 136.95
## GABRA1 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## NLRP2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SLC45A4 4.31 5.93 4.15 5.68 2.76 5.83 5.07
## RNF10 76.77 86.17 84.90 71.79 74.11 82.99 83.18
## ZNF839 5.49 4.93 4.28 4.70 4.91 5.40 4.09
## ZDHHC6 14.56 19.63 19.79 12.47 11.35 13.22 12.80
## GRAMD1B 0.58 0.75 0.39 0.51 0.37 0.56 0.32
## RNH1 311.39 309.24 298.29 291.27 318.35 315.00 280.87
## NDUFS1 42.79 54.93 42.75 39.55 55.31 46.82 32.35
## RB1CC1 47.14 36.58 48.94 74.29 42.90 67.65 70.49
## ERP44 20.82 17.70 21.62 17.64 16.49 17.74 19.73
## ALAS1 42.06 48.11 41.69 33.18 47.93 42.76 33.43
## BIRC3 27.32 10.03 20.53 4.56 10.21 4.24 1.77
## AKAP11 7.44 10.77 9.31 9.07 4.24 9.86 7.47
## GLRX2 23.25 40.69 29.89 29.17 17.70 26.77 42.92
## SNAPC1 3.36 4.13 3.69 2.69 3.39 2.92 3.72
## DERA 45.29 43.72 40.44 38.35 23.44 37.68 30.40
## STRAP 116.42 131.56 129.98 109.48 109.09 105.19 113.22
## ABCC2 0.47 1.00 0.74 0.90 0.23 1.29 0.85
## DEF6 0.11 0.13 0.12 0.07 0.08 0.09 0.03
## PLEKHO1 27.54 29.58 29.43 41.31 25.80 32.95 62.16
## GCLM 89.32 77.02 87.44 165.68 43.63 157.62 183.67
## UBR2 9.37 10.06 8.14 8.27 5.43 9.18 7.05
## EHD2 105.01 72.70 104.17 75.63 55.12 83.49 58.96
## DEPDC1 11.20 24.75 16.34 6.18 5.36 11.49 3.70
## CCDC28A 16.91 11.15 13.26 14.26 18.68 12.47 15.67
## RRAGD 0.12 0.09 0.09 0.08 2.18 0.07 0.29
## HSF2 8.21 7.87 9.88 8.66 6.96 8.46 10.38
## PHF20 22.00 21.28 19.84 18.19 11.58 20.11 14.02
## HSD17B6 0.50 0.42 0.45 0.58 0.58 0.18 0.27
## NR1H3 18.45 28.37 19.38 17.55 17.93 26.18 16.31
## TYMP 5.70 4.61 4.31 5.44 7.15 5.66 5.61
## NCAPH2 73.10 95.97 87.97 50.23 48.20 57.29 33.97
## TOMM34 128.91 97.27 120.29 117.81 103.36 94.32 91.74
## SEC63 39.61 48.02 47.39 33.75 28.02 45.19 43.05
## KPNA6 23.83 25.28 23.69 22.11 19.97 25.45 16.70
## VIM 3143.27 1709.72 3478.65 2026.67 3326.54 1665.89 1473.45
## RTEL1-TNFRSF6B 3.42 5.41 3.28 3.48 2.66 5.02 2.06
## FAS 6.16 5.63 5.92 5.77 3.94 5.84 3.47
## RNASET2 20.63 20.47 17.08 29.22 15.18 27.36 31.19
## CD44 1410.08 720.30 1501.59 791.50 1666.77 688.20 503.77
## KCNG1 15.18 11.79 15.65 7.50 8.43 8.27 9.59
## AGPAT4 15.52 7.92 15.26 10.34 19.04 7.61 11.15
## SLAMF7 0.00 0.00 0.00 0.08 0.07 0.01 0.03
## BTN3A1 23.04 17.05 18.72 13.33 22.81 17.55 8.62
## MIPEP 15.13 19.04 16.91 18.24 13.03 19.35 17.82
## PRKCH 0.27 0.32 0.23 0.19 0.20 0.25 0.29
## INSRR 0.00 0.01 0.01 0.00 0.01 0.00 0.01
## IFNGR1 34.55 26.22 31.82 34.95 28.93 32.59 38.31
## B4GALT7 50.63 34.66 38.75 43.64 67.81 48.19 45.47
## SH2D2A 0.29 0.16 0.24 0.25 1.16 0.29 0.27
## VRK2 13.81 18.69 15.45 11.71 14.74 12.56 10.52
## TNFRSF1B 1.24 0.70 0.77 0.48 0.62 0.48 0.29
## VEZT 16.43 20.41 14.26 22.13 16.11 20.33 22.99
## POU2F2 0.70 0.33 0.67 0.22 0.50 0.20 0.20
## BRD9 49.68 38.03 45.54 40.64 61.26 45.21 34.97
## SNX1 53.96 71.68 51.13 53.71 40.95 62.47 42.33
## TBPL1 17.00 20.03 17.99 19.24 10.25 19.74 20.71
## ARNTL2 26.78 13.89 24.92 13.15 10.24 8.16 5.50
## BCLAF1 77.34 81.38 86.50 69.05 35.17 74.47 41.85
## SLC39A9 25.30 23.19 28.61 25.36 23.41 22.34 18.31
## ANK1 1.48 2.18 2.36 0.55 0.29 0.55 0.44
## IBSP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TFB1M 11.26 9.46 10.12 6.99 11.31 8.55 6.91
## RABEP1 26.29 36.75 33.69 34.57 28.73 34.99 32.52
## HMGB3 47.21 73.70 57.74 43.47 32.04 51.35 30.90
## NUP160 29.29 35.30 29.92 22.09 14.93 26.29 15.30
## BAK1 21.57 22.68 23.06 20.97 18.97 19.76 17.59
## MUSK 0.34 0.18 0.28 0.32 0.38 0.21 0.33
## IKZF2 0.17 0.27 0.17 0.43 0.96 0.30 0.16
## GRN 252.99 220.85 202.09 340.05 253.41 361.74 422.10
## FAM13B 6.94 10.85 8.72 7.87 4.18 8.05 4.87
## ARHGAP31 2.93 3.80 3.12 3.21 1.23 2.70 2.01
## CENPQ 12.56 19.14 15.43 9.32 4.18 8.66 7.10
## SARS 149.42 138.16 152.21 119.09 234.97 120.66 128.91
## RANBP3 50.95 50.86 49.12 42.86 39.88 52.19 42.63
## ARID4A 3.12 2.45 2.64 3.16 1.57 3.63 2.59
## TSSC1 11.71 14.78 11.15 10.01 12.57 12.00 10.11
## PNPLA6 50.60 66.89 56.81 37.02 38.03 44.35 31.02
## IFT88 8.20 11.97 8.45 10.15 6.77 10.78 10.60
## ALG1 24.52 35.24 24.56 32.80 26.56 35.84 35.10
## ZCCHC8 9.77 9.52 10.54 10.66 10.16 11.53 11.81
## ABCF2 50.70 74.47 54.40 50.98 36.66 64.28 42.09
## CHPF2 57.17 54.50 52.12 78.64 26.69 92.14 77.38
## LRRC7 0.23 0.17 0.15 0.06 0.11 0.28 0.21
## FUT8 17.53 18.02 17.51 14.56 10.31 14.58 11.75
## UBA6 8.33 10.19 8.88 6.84 4.42 8.16 5.75
## GAB2 1.88 1.53 2.90 6.17 3.79 3.52 5.99
## ATP6V0A1 23.90 22.96 18.75 38.48 45.76 36.11 46.57
## PIAS1 18.29 19.07 19.10 16.84 11.36 17.53 15.19
## SLC4A7 48.45 38.79 39.81 45.24 29.66 37.60 26.03
## APBA2 11.44 12.51 11.19 8.32 6.53 9.92 6.91
## MAP2K3 33.15 28.08 37.78 20.35 19.61 21.23 17.79
## EFCAB1 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## TMSB10 6094.03 4206.74 5573.14 4298.59 5552.74 3534.34 4171.88
## ASTE1 4.34 4.73 4.32 3.88 3.78 4.25 3.52
## RNF19A 15.01 13.41 15.38 10.46 7.06 10.67 8.41
## PEX3 16.43 19.68 18.81 21.53 16.67 19.47 25.84
## GABARAPL2 161.43 151.79 152.44 167.64 143.16 151.56 204.41
## MYOC 0.00 0.00 0.02 0.00 0.00 0.00 0.00
## SH3YL1 14.08 7.76 13.17 15.94 22.46 12.74 14.29
## FAM136A 45.61 52.71 51.24 40.05 28.86 37.41 38.26
## VCL 66.68 42.07 47.10 37.67 30.41 37.34 23.82
## DEPDC1B 7.17 11.77 7.12 4.71 2.41 7.80 2.08
## DAPK2 2.65 0.48 1.28 0.57 0.48 0.48 0.58
## NSMAF 32.62 36.83 35.38 42.24 32.66 41.65 43.83
## ADSS 32.58 42.19 33.70 47.02 43.15 48.51 43.63
## STAP1 0.00 0.00 0.02 0.00 0.00 0.00 0.00
## TIMP2 371.66 275.15 323.98 432.60 312.65 387.94 423.25
## RFC1 25.02 25.76 25.41 19.21 15.45 18.04 15.86
## TBC1D23 28.89 23.23 29.91 24.61 21.34 21.55 25.73
## CUL3 71.78 80.91 83.56 92.53 50.39 80.39 97.88
## MYOM2 1.63 1.05 1.56 3.16 2.72 1.93 4.29
## OTC 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CYP46A1 0.20 0.51 0.23 0.48 0.70 0.45 0.33
## ZZZ3 30.04 33.20 36.74 33.70 27.37 32.93 29.60
## SLC18A1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## USP2 0.40 0.56 0.35 0.26 0.83 0.35 0.21
## CASR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TUBG2 18.36 17.98 16.66 10.09 13.05 15.40 11.66
## RPL26L1 114.68 117.70 102.32 96.47 117.81 92.58 110.79
## FLT4 0.00 0.00 0.00 0.00 0.02 0.00 0.00
## NSUN2 37.82 49.41 43.66 29.97 24.46 38.48 28.16
## FBXO42 11.20 11.12 10.22 11.41 7.61 11.83 9.85
## MFAP3 19.58 21.31 20.93 16.95 14.32 17.55 13.65
## MRI1 16.74 20.55 18.84 13.07 7.03 18.62 11.64
## METTL1 16.64 19.39 17.40 19.17 31.75 19.90 15.22
## HOXC8 2.59 2.95 2.23 2.00 1.01 2.91 1.95
## AGA 19.23 22.77 16.90 16.75 10.99 17.55 16.01
## PI4K2B 12.95 13.90 15.69 9.85 7.49 9.64 8.60
## BOD1L1 14.00 11.73 15.35 14.48 10.63 15.13 14.34
## MAT2B 63.30 74.84 62.02 51.22 44.34 65.24 51.87
## TLL1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## EDC4 48.80 51.83 44.59 31.54 29.80 44.06 29.78
## TRIO 49.61 33.62 46.51 56.80 22.77 48.89 51.67
## VCAN 0.23 0.08 0.06 0.23 0.28 0.16 0.03
## CLEC16A 8.05 10.94 7.81 6.91 9.30 10.16 8.28
## MSR1 0.04 0.00 0.00 0.00 0.00 0.00 0.00
## CDH1 0.00 0.01 0.08 0.00 0.00 0.00 0.11
## SKIV2L2 47.04 44.69 47.81 35.83 37.63 39.36 33.18
## DNAH5 10.85 3.70 8.34 5.92 7.21 5.63 4.90
## ZFYVE16 14.96 15.34 18.87 21.93 8.36 14.47 25.60
## FAM65A 63.61 55.99 75.61 58.58 62.98 66.17 49.53
## C6 0.23 0.12 0.12 0.11 0.01 0.01 0.02
## RAI14 64.29 27.10 58.93 57.29 42.18 40.35 45.51
## SOX30 0.16 0.03 0.11 0.04 0.01 0.12 0.15
## PNKP 10.56 19.71 12.15 12.36 15.12 14.03 10.63
## BEST2 0.04 0.02 0.02 0.02 0.00 0.00 0.01
## PHLPP2 3.64 5.29 4.56 3.46 1.89 3.41 2.36
## SPDL1 25.56 37.19 32.14 18.07 11.01 22.56 13.76
## STAU2 24.12 30.44 25.59 23.26 14.21 28.15 19.28
## PQLC2 17.96 20.78 19.23 28.19 17.50 23.98 30.88
## CTNS 8.64 12.92 7.87 14.42 11.31 15.44 12.98
## RTN4R 4.08 2.81 4.17 2.31 5.17 1.99 2.37
## PHF23 38.64 49.47 38.57 59.09 26.36 59.26 64.48
## CDH10 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## INPP4A 9.12 9.51 8.82 6.83 4.30 8.98 6.26
## RAB27B 8.36 7.21 7.40 11.24 17.92 9.32 8.80
## PSMA4 188.05 275.43 192.87 205.54 127.80 198.61 254.83
## MYO16 0.06 0.05 0.02 0.09 0.04 0.04 0.06
## LSG1 21.33 33.39 24.17 26.17 23.01 29.41 19.10
## PARP3 38.61 30.94 31.16 35.41 35.79 36.70 30.07
## TNC 23.05 19.67 25.55 11.08 11.22 11.11 3.91
## THAP3 27.90 21.05 24.59 20.10 27.57 21.90 23.52
## FAM65C 10.64 7.36 8.07 5.65 2.98 5.42 3.25
## TDP1 8.39 9.79 8.68 6.78 2.77 8.24 5.52
## AIFM2 15.85 18.53 14.19 18.04 13.77 18.24 19.99
## C2orf83 0.00 0.00 0.00 0.00 0.00 0.00 0.03
## SPATA7 3.70 3.79 2.95 3.20 2.72 2.81 2.76
## MED17 35.04 36.86 37.40 34.17 19.31 38.01 33.36
## RETSAT 24.25 26.45 23.91 28.58 21.70 29.88 24.29
## CAPG 2.73 3.06 2.08 2.44 4.39 2.27 2.83
## AP2S1 252.54 261.13 225.27 268.73 287.62 236.35 259.00
## USH2A 0.01 0.00 0.00 0.00 0.01 0.00 0.00
## ZPBP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TG 1.53 1.21 0.99 0.50 1.13 0.82 0.28
## ADAM28 0.12 0.58 0.26 0.59 0.19 1.02 0.89
## BARX2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DCUN1D1 22.27 26.68 22.55 27.23 15.27 23.22 20.95
## JADE2 13.78 35.08 22.92 13.56 16.29 17.29 8.90
## ZIC2 15.55 17.73 16.60 13.21 9.80 14.41 12.67
## LCP2 0.03 0.21 0.57 0.18 0.30 0.13 0.06
## TRIT1 16.98 12.55 17.40 12.74 10.18 13.80 11.30
## ADRB1 0.41 0.45 0.47 0.46 0.22 0.75 0.18
## GUCA2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CUL7 28.00 21.14 24.23 27.35 36.62 30.40 20.85
## CTNNA1 217.57 200.63 196.16 166.97 142.45 172.68 163.09
## PHKA2 11.30 12.68 11.73 9.53 10.13 15.24 8.46
## CNTLN 4.22 5.91 4.94 3.60 2.16 3.85 3.19
## EPHA3 0.00 0.02 0.05 0.00 0.00 0.00 0.03
## HSPA5 441.45 194.90 345.17 419.05 398.87 334.04 495.47
## DSG2 0.08 0.01 0.04 0.02 0.00 0.01 0.02
## GEMIN8 13.92 11.23 12.53 16.75 12.52 15.76 15.32
## OFD1 11.28 8.71 11.32 13.08 11.01 15.13 12.25
## GPM6B 0.06 0.09 0.03 0.07 0.00 0.08 0.03
## MAGEC2 0.38 0.24 0.31 0.12 0.43 0.40 0.24
## PREX2 0.85 2.03 0.69 0.67 1.18 1.47 0.44
## WDR37 6.37 4.57 6.55 7.72 3.72 6.86 6.38
## YTHDC2 4.66 6.40 4.54 4.50 3.65 6.47 4.77
## CTPS2 4.08 5.19 3.87 3.62 2.99 4.39 2.69
## ATP6V1H 40.55 45.40 38.79 53.69 66.64 51.62 58.52
## POLR2B 52.48 61.51 53.28 54.03 38.72 60.74 48.88
## FAM214A 8.95 8.62 8.75 13.69 8.15 12.68 13.75
## ARAP2 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## TPR 43.70 46.06 37.09 39.48 30.95 50.55 37.49
## CP 7.96 14.78 13.94 15.35 19.26 16.39 15.19
## KIAA0556 8.95 10.77 8.22 7.86 8.59 9.56 6.03
## DTNBP1 19.58 22.11 19.96 18.48 12.55 20.05 18.16
## XK 0.00 0.01 0.00 0.00 0.01 0.00 0.00
## ANO2 0.04 0.02 0.06 0.00 0.15 0.01 0.00
## C12orf4 5.30 9.22 8.09 8.83 8.79 7.44 7.66
## SCML1 11.85 13.91 13.86 13.96 9.62 13.62 19.93
## WWC3 11.21 10.27 10.11 7.86 5.26 9.30 5.83
## ARHGAP6 0.00 0.04 0.04 0.01 0.08 0.03 0.03
## FAM184B 1.20 0.95 0.88 1.16 0.96 1.85 1.15
## MAP4 149.78 105.44 131.49 109.95 80.81 112.20 84.81
## GOPC 15.09 15.43 15.50 13.76 8.54 14.71 12.69
## ROS1 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## USP28 12.56 13.50 10.98 7.63 5.42 10.42 6.86
## HDAC9 10.22 8.43 9.44 6.27 2.98 4.54 3.89
## TSPAN17 53.70 72.01 59.00 60.66 45.75 61.86 51.74
## NOP16 39.34 53.28 44.45 47.02 27.30 51.01 46.84
## CC2D2A 4.56 5.33 3.96 3.31 5.71 4.81 3.15
## RRM2B 16.33 17.42 15.54 16.94 12.93 17.76 14.89
## ZNF800 11.49 11.97 12.20 12.26 8.45 12.31 8.52
## TNFRSF17 0.00 0.12 0.15 0.07 0.00 0.00 0.00
## SNX29 6.75 9.30 8.31 9.00 6.92 7.47 7.79
## LMO3 0.44 0.23 0.33 0.41 0.01 0.58 0.58
## MRPS10 54.63 54.85 58.73 58.90 70.35 47.00 60.91
## GUCA1A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RSF1 15.44 16.76 14.13 15.41 14.85 15.65 9.76
## VPS13D 10.66 9.41 8.23 9.11 5.48 10.48 8.76
## CELF2 0.49 0.72 0.44 0.42 0.56 0.50 0.35
## FAM120A 59.89 68.94 60.49 48.08 32.42 57.54 48.04
## R3HDM1 16.30 25.02 20.94 18.02 6.44 19.72 13.09
## COL9A2 0.03 0.00 0.08 0.01 0.04 0.09 0.01
## KITLG 12.24 9.32 18.23 18.38 2.64 16.08 14.07
## ERCC8 14.43 17.37 13.86 13.61 6.46 14.15 12.69
## ADAMTS6 0.85 0.36 0.63 0.12 0.17 0.24 0.07
## H6PD 17.98 10.48 12.29 12.00 19.59 14.14 7.46
## VAMP3 116.90 105.40 115.94 115.08 120.38 95.96 111.87
## PER3 8.91 7.73 8.24 6.64 5.97 7.05 5.00
## UTS2 0.09 0.00 0.12 0.08 0.07 0.00 0.00
## TNFRSF9 4.46 1.35 4.35 4.48 6.86 1.90 2.35
## EPN3 0.07 0.05 0.09 0.03 0.12 0.08 0.02
## LTBP1 14.52 7.12 13.73 7.80 3.33 7.49 4.81
## RCN1 407.83 311.36 397.11 408.25 276.00 357.04 503.12
## ELN 0.00 0.00 0.00 0.01 0.11 0.00 0.00
## RFC2 56.47 68.48 62.64 38.14 35.21 33.80 29.27
## ARID1B 7.97 11.01 7.56 6.61 3.42 8.54 4.66
## CLPTM1L 86.98 105.30 94.48 93.98 62.72 101.21 95.08
## NEDD4L 14.16 10.13 10.94 13.00 17.12 10.57 15.44
## FOXP3 0.05 0.00 0.01 0.07 0.23 0.05 0.07
## PPP1R3F 5.04 6.64 5.54 3.78 2.36 3.35 4.35
## HEXB 242.33 217.51 244.64 344.29 233.86 288.49 421.60
## PTCD2 7.52 7.42 5.85 9.14 13.48 9.86 8.96
## KIAA2022 0.01 0.00 0.00 0.00 0.00 0.00 0.00
## JKAMP 39.36 42.04 42.39 48.40 33.31 44.18 48.35
## DKK3 367.08 250.81 343.95 294.34 248.34 244.61 242.47
## ARHGEF5 0.00 0.00 0.02 0.01 0.04 0.00 0.01
## NFE2L3 43.38 18.64 28.32 14.85 11.99 18.00 10.21
## MCUR1 29.22 34.49 34.23 29.97 25.17 25.37 29.72
## LIMA1 52.33 64.48 48.15 39.99 23.81 48.94 31.69
## LETMD1 52.37 36.15 49.29 55.84 78.42 53.91 46.69
## SLC4A8 0.77 0.49 0.46 0.36 0.84 0.42 0.43
## LAMC3 0.01 0.02 0.01 0.05 0.01 0.10 0.00
## PTGER3 0.32 0.55 0.40 0.12 0.06 0.27 0.10
## TNIP3 0.60 0.38 0.85 0.51 0.27 0.60 0.37
## MAPK9 38.52 50.65 44.81 34.81 20.04 33.43 33.71
## COL23A1 0.01 0.01 0.03 0.05 0.06 0.03 0.04
## BCAR1 88.96 76.17 76.13 115.27 76.71 83.98 111.00
## FAM160A2 14.42 12.10 12.07 14.98 26.15 17.06 13.50
## HERPUD1 94.29 62.28 84.64 105.37 76.39 77.62 131.94
## HOMER3 78.05 90.05 92.33 95.11 69.34 81.65 97.63
## RAD51 14.91 18.23 20.09 6.65 3.12 5.52 2.85
## POLQ 1.71 4.37 2.79 1.63 0.62 1.66 0.66
## PIK3CB 11.22 11.93 11.90 10.47 11.21 10.24 7.97
## CYBA 0.00 0.11 0.20 0.00 0.09 0.02 0.04
## THOC3 58.98 66.04 61.27 40.18 34.52 45.26 36.88
## HEBP2 96.38 78.84 85.98 73.89 91.29 60.92 71.51
## MPHOSPH9 11.51 19.50 11.80 10.77 9.35 16.25 9.39
## PLEKHA5 6.55 8.14 6.54 5.61 7.19 6.26 4.23
## PRSS8 0.06 0.09 0.00 0.02 0.02 0.10 0.02
## SIKE1 32.86 22.61 28.14 25.33 54.65 23.25 21.20
## RRP12 16.39 17.15 15.09 15.46 20.15 22.29 14.57
## FNIP2 2.38 3.38 2.68 4.24 2.27 2.89 3.24
## MSMO1 24.09 23.75 22.02 41.70 16.66 23.43 94.76
## TTC17 38.04 49.87 47.56 32.65 26.77 41.74 25.10
## ALX4 6.05 11.44 6.44 10.34 6.56 14.59 6.09
## FSTL4 0.16 0.07 0.12 0.15 0.16 0.05 0.20
## FOXN3 7.14 10.99 7.92 9.05 5.52 10.40 6.05
## METTL24 0.00 0.00 0.00 0.10 0.00 0.00 0.00
## AKR7A2 80.41 72.24 74.43 71.72 92.09 68.02 64.75
## MRTO4 35.36 41.63 41.06 35.84 41.43 38.53 30.09
## NNAT 0.46 0.54 1.00 0.86 0.18 0.96 0.42
## USE1 18.88 19.46 14.21 15.33 37.68 15.15 13.95
## MCF2L2 0.14 0.02 0.31 0.39 0.93 0.37 0.18
## NRIP2 0.53 0.38 0.48 0.55 1.79 0.74 0.25
## LAMA3 3.39 3.67 4.17 4.24 2.96 3.97 3.02
## AP5M1 6.06 10.33 9.34 9.36 3.97 8.75 9.08
## ANAPC4 9.59 13.13 10.02 9.54 8.17 10.28 8.48
## KCNQ1 0.04 0.00 0.08 0.04 0.12 0.03 0.00
## TRAPPC3 71.54 93.86 83.55 91.97 58.06 90.22 93.63
## THRAP3 54.42 49.58 51.57 46.41 41.60 51.21 36.89
## PHPT1 126.59 91.09 123.46 112.40 143.45 102.69 102.03
## ENTPD2 0.12 0.00 0.03 0.07 0.15 0.04 0.10
## LY75 0.00 0.01 0.01 0.00 0.00 0.00 0.00
## ARID4B 14.02 12.06 12.29 14.18 8.76 15.00 12.01
## OPN3 32.06 17.23 29.24 21.39 6.00 27.27 22.60
## SDCCAG8 29.37 23.41 26.03 27.86 21.74 25.41 27.61
## PTPRN 20.99 9.76 24.42 43.17 48.20 30.73 42.75
## HHAT 2.67 1.74 1.60 2.89 2.88 2.45 2.07
## KIF1B 10.53 11.76 11.54 13.36 6.84 10.88 12.87
## FOXC1 5.43 5.45 5.77 4.46 3.64 4.61 4.25
## TBC1D22A 42.66 37.39 35.87 39.73 45.72 38.89 34.91
## SYNE2 4.12 5.39 3.51 2.46 1.25 3.46 1.91
## PLEKHH1 0.27 0.43 0.32 0.32 0.42 0.54 0.26
## ATP9A 25.00 21.63 22.47 21.52 12.02 21.00 13.81
## SPO11 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CBLN4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CHRDL2 0.16 0.00 0.19 0.03 0.07 0.04 0.14
## FAM168A 21.60 23.95 24.68 18.31 13.45 20.44 9.42
## RELT 7.86 10.93 9.70 8.66 7.93 7.01 7.24
## GALC 0.07 0.08 0.00 0.00 0.06 0.11 0.06
## NOP58 65.54 66.32 72.33 51.36 47.95 59.13 47.55
## SZRD1 138.06 149.07 141.54 146.25 92.27 130.15 96.60
## KCNH2 0.05 0.10 0.08 0.03 0.07 0.02 0.00
## CUL1 36.05 45.60 37.84 41.36 15.07 39.16 40.80
## FAM114A2 18.76 16.48 16.32 25.17 22.14 18.22 17.02
## CYFIP2 0.84 0.35 0.69 0.25 0.84 0.33 0.37
## TAB2 31.99 32.92 34.76 28.46 14.43 29.31 21.37
## GINM1 32.29 27.80 30.42 38.93 43.82 33.49 43.81
## EIF2AK2 13.17 20.75 17.37 11.63 9.07 14.03 8.84
## USP36 31.48 25.84 31.79 35.72 49.24 38.27 33.03
## KMT2C 7.27 10.75 8.18 8.33 4.00 9.64 8.70
## MCOLN3 1.52 2.56 1.57 2.12 1.44 2.69 1.89
## CCDC85A 0.02 0.00 0.00 0.00 0.00 0.00 0.00
## PUM2 19.79 22.62 20.46 19.58 9.33 19.11 15.45
## MRPL43 61.32 53.33 53.29 61.13 65.99 58.85 64.79
## ITIH4 2.75 1.31 1.57 1.80 1.08 1.96 0.87
## ITIH1 0.00 0.00 0.06 0.06 0.15 0.00 0.05
## C4orf27 24.32 30.02 29.09 16.42 11.90 18.60 19.41
## ZFR 33.28 38.35 38.35 33.04 33.30 33.93 32.04
## ZNF280C 2.73 2.54 2.59 2.19 2.01 3.06 1.99
## NPFFR2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PHF21B 1.12 1.53 1.01 0.93 0.92 1.42 0.69
## TRAF1 3.86 1.20 2.10 2.12 2.63 1.11 1.75
## RC3H2 12.08 15.35 14.00 25.24 16.93 23.99 8.19
## PCGF2 34.11 33.56 32.60 29.03 24.69 32.98 33.78
## IL17RB 0.95 1.14 1.15 1.09 0.23 1.08 1.02
## TRAF3IP2 21.09 19.65 22.16 24.93 36.32 25.27 24.18
## GYG2 4.01 6.63 3.21 2.54 1.35 5.03 2.07
## DCBLD2 92.59 56.41 120.21 63.64 38.15 48.14 47.92
## SERPINB3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SOAT1 25.78 39.58 27.46 32.00 25.80 31.75 22.78
## PKP2 0.27 0.15 0.26 0.33 0.48 0.21 0.07
## MSH4 0.02 0.00 0.01 0.00 0.00 0.00 0.01
## F7 0.00 0.00 0.01 0.00 0.00 0.00 0.02
## GDI2 155.34 166.43 195.95 134.71 102.97 124.43 111.18
## PRDM1 4.16 2.46 2.19 2.70 1.94 2.75 1.65
## ATG5 15.99 16.85 16.87 13.05 10.48 12.24 12.63
## TMCC3 0.21 0.01 0.07 0.04 0.18 0.02 0.04
## PITHD1 66.17 36.20 77.67 58.24 49.93 42.05 74.22
## MTA3 22.61 28.12 20.87 19.08 21.06 25.91 20.96
## USP13 8.95 11.34 9.40 6.89 7.04 8.77 4.79
## ATP11B 12.49 11.80 14.02 9.11 8.78 10.44 8.00
## LAMC2 1.37 1.10 1.83 1.03 0.82 0.77 0.88
## CDK14 4.72 6.93 6.74 4.73 4.40 5.15 3.05
## SEC61A1 227.96 198.65 269.65 205.66 142.74 190.01 168.66
## PPP1R12A 21.98 19.24 22.16 16.94 8.54 18.00 13.86
## RASGRF1 0.24 0.17 0.13 0.26 0.47 0.19 0.15
## CAMK2B 0.28 0.22 0.09 0.04 0.50 0.07 0.05
## CROCC 7.55 8.62 4.84 7.71 5.71 10.94 8.12
## POLR3E 21.09 29.36 22.25 25.04 19.92 29.52 29.02
## ATP2B4 33.98 22.32 40.03 26.52 15.70 21.53 19.25
## ZC3H11A 60.80 70.45 67.95 46.46 23.10 57.24 39.08
## RIOK2 30.15 31.22 33.36 33.35 30.27 29.03 36.91
## YIPF1 30.54 34.42 26.73 30.69 30.97 31.31 27.06
## NDC1 14.47 26.91 20.05 12.17 5.74 15.39 7.13
## DGKG 7.31 6.33 6.91 11.54 7.90 8.46 10.08
## FLYWCH1 42.62 40.69 42.15 58.64 38.05 60.25 63.91
## UNKL 29.75 28.55 28.86 38.29 20.34 45.29 38.95
## TBXAS1 49.15 137.08 73.64 61.73 13.28 97.22 56.99
## PARP12 18.55 20.04 17.68 12.43 11.84 16.90 10.27
## ALDH18A1 51.94 33.74 49.75 32.64 50.28 38.08 29.10
## TARBP1 19.35 18.92 15.29 17.49 12.54 24.94 17.45
## PET112 17.70 16.49 16.07 20.34 19.45 19.57 24.87
## MXD1 3.94 2.56 4.70 5.67 6.52 3.57 6.50
## CDK17 11.46 11.99 11.20 11.14 8.98 11.85 10.67
## DNAJC25 30.08 21.93 30.51 26.33 25.90 22.33 12.58
## SLC2A3 48.73 20.03 28.16 49.34 54.08 55.59 47.73
## PSD 1.55 1.91 1.97 1.58 2.62 1.59 1.17
## CTDP1 8.79 9.68 8.54 9.77 7.22 9.49 10.10
## YBX3 280.32 218.99 227.46 289.79 364.26 319.18 311.17
## STYK1 0.95 0.44 0.74 1.38 1.04 1.39 1.29
## WNK1 29.67 37.62 30.62 33.25 16.47 37.16 21.54
## CCAR1 22.93 41.96 29.74 26.67 22.23 33.78 29.93
## OGFR 73.64 88.82 64.22 59.10 57.82 70.75 54.61
## GNA15 0.00 0.00 0.02 0.02 0.04 0.01 0.06
## CREB3L3 0.00 0.02 0.00 0.01 0.06 0.01 0.00
## PIGV 15.40 16.51 13.59 12.87 13.39 14.74 10.55
## PTPRU 18.43 19.49 17.24 14.86 11.01 18.68 10.08
## SNRNP40 46.02 57.39 48.01 36.89 27.87 39.79 35.94
## RIMBP2 0.02 0.00 0.03 0.01 0.15 0.01 0.00
## COL11A1 0.06 0.02 0.05 0.02 0.00 0.15 0.05
## QSER1 11.14 11.42 12.14 10.94 5.31 11.55 8.09
## MPC1 32.21 36.33 33.75 40.50 57.50 29.62 55.69
## ACAA1 32.32 36.55 29.51 33.86 57.66 43.24 32.90
## BCAT1 13.13 10.58 15.42 7.75 7.16 8.40 5.47
## HDAC7 40.88 37.62 39.79 22.54 16.95 28.83 17.57
## LZTS1 5.54 7.68 5.36 3.04 1.40 3.96 1.48
## PRDM6 0.33 0.50 0.47 0.59 0.41 0.51 0.40
## WNT8A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SPAG4 20.93 14.25 23.13 23.39 29.73 20.25 17.57
## NCKAP1 47.78 57.41 46.34 43.77 31.09 47.54 45.28
## MRPS35 44.88 50.15 49.07 44.00 54.32 44.37 46.40
## GUCY1B3 0.00 0.08 0.09 0.00 0.01 0.04 0.00
## SFSWAP 19.41 18.27 19.93 18.79 20.26 22.10 18.07
## TNK2 26.57 31.01 28.07 25.60 21.44 33.64 27.77
## MON2 11.09 10.12 9.75 8.10 12.44 11.79 7.39
## CDH3 0.43 0.05 0.10 0.11 0.12 0.07 0.06
## ARSF 0.02 0.02 0.02 0.04 0.00 0.01 0.00
## GPBP1 58.39 54.23 60.39 49.09 38.36 54.42 46.75
## DGAT2 8.53 9.30 8.07 7.38 8.05 8.26 6.59
## ZNF112 0.86 2.57 1.28 1.43 0.96 1.70 0.95
## CS 97.04 122.17 112.46 85.21 90.76 101.51 66.00
## LTK 5.04 8.76 6.83 5.73 3.49 8.24 4.38
## MRPS24 190.67 200.80 192.22 149.40 224.51 148.63 163.90
## ELMO2 34.03 46.51 30.64 39.03 36.30 42.89 32.25
## WAPAL 14.17 13.97 12.59 11.38 7.81 13.14 11.98
## VMP1 229.74 157.22 188.44 194.50 206.06 222.05 202.28
## APPBP2 12.63 16.34 15.80 13.29 6.22 15.02 11.95
## POLD1 28.80 42.59 32.70 15.69 11.58 20.83 11.26
## SEZ6 0.05 0.08 0.04 0.19 0.05 0.00 0.00
## EIF4B 164.03 164.56 178.75 186.78 193.25 177.64 153.40
## SLC6A16 1.11 3.06 1.99 0.96 0.23 2.05 0.64
## GLTSCR1 6.05 4.81 5.76 6.59 3.59 6.48 4.93
## SPHK2 10.37 16.59 10.08 14.94 10.03 15.98 16.86
## RPL18 2036.40 1683.72 1853.96 2015.21 2654.32 1677.43 2186.86
## CA11 3.99 5.62 4.32 13.12 6.55 8.74 6.46
## ISOC2 91.82 109.97 86.64 96.70 92.86 96.08 99.37
## U2AF2 97.76 136.57 101.75 108.22 86.00 123.59 84.80
## EPN1 111.51 117.29 115.46 90.91 85.25 100.60 78.31
## MED29 37.31 30.79 29.70 30.93 45.78 31.30 28.86
## AHRR 39.74 48.13 45.28 39.05 22.10 50.10 22.15
## GSC2 0.00 0.00 0.04 0.00 0.00 0.00 0.00
## ZNF275 8.67 6.40 10.14 8.64 5.49 7.70 6.60
## MTMR1 17.71 16.93 16.67 11.32 6.02 13.85 8.06
## GPC1 178.94 140.73 171.14 257.84 138.05 282.92 252.96
## ADCK1 2.08 2.89 1.70 2.12 1.70 2.83 1.70
## HAGH 46.92 51.83 48.04 33.45 49.37 34.84 35.22
## RNF4 34.14 37.35 34.88 30.81 25.62 31.97 23.21
## CASP8 14.83 17.29 10.19 16.72 11.41 20.16 12.74
## LIMCH1 68.55 79.02 56.00 26.73 11.00 38.99 15.70
## ASUN 23.56 34.74 28.34 22.62 9.63 26.71 24.22
## TM7SF3 26.82 31.79 25.29 24.90 15.11 24.38 20.58
## DLX3 1.46 7.48 2.33 1.61 0.76 1.12 0.29
## SPA17 15.55 18.36 15.41 13.99 8.10 10.99 13.62
## TSPAN32 0.29 0.45 0.24 0.49 0.51 0.92 0.21
## WISP2 0.20 0.11 0.26 1.24 0.89 0.73 1.50
## DMRT3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ST3GAL6 1.83 4.27 1.67 2.75 0.99 2.36 1.85
## ATP2C2 0.04 0.26 0.02 0.01 0.10 0.17 0.14
## NGFR 0.74 0.21 0.34 0.55 43.78 0.17 0.55
## CDON 7.43 8.10 7.02 10.07 11.41 12.35 4.73
## TAF2 16.85 20.96 16.42 15.41 10.28 18.05 12.31
## HIPK2 31.68 46.68 44.19 33.70 21.85 38.89 23.50
## TNPO3 30.03 34.15 36.27 26.51 23.32 29.15 19.47
## MEF2BNB-MEF2B 2.38 1.95 3.77 4.00 3.41 2.96 2.36
## RFXANK 93.95 88.53 78.53 61.97 75.27 71.56 64.22
## TMEM161A 31.34 29.36 24.27 37.55 31.28 42.56 48.73
## LPAR2 6.48 7.92 6.28 4.82 2.88 5.21 3.88
## CTSA 296.55 244.78 244.24 441.82 397.14 401.10 595.73
## SUGP2 27.80 33.43 34.02 23.65 14.05 28.95 21.71
## SLC12A2 3.65 7.07 5.31 5.12 3.61 6.10 4.52
## SNX24 13.15 12.54 12.17 11.82 12.43 10.14 10.02
## EYA2 2.09 1.66 2.32 1.20 1.63 1.10 0.68
## CNN2 200.50 89.80 114.10 52.94 88.97 65.60 32.22
## ABCA7 5.17 8.68 4.62 5.38 2.07 8.43 3.86
## SNCAIP 13.14 29.61 14.36 8.91 6.84 26.33 5.37
## DDX20 8.49 11.73 9.23 10.14 3.64 9.96 8.09
## BTBD1 46.43 50.73 46.10 39.82 35.10 41.11 44.30
## FAR2 1.44 2.82 2.49 1.84 0.81 2.20 1.25
## BCAS1 0.01 0.06 0.03 0.00 0.03 0.01 0.02
## POU1F1 0.00 0.03 0.00 0.00 0.00 0.09 0.00
## CHI3L2 5.32 2.51 6.50 18.87 17.22 12.85 21.52
## SBNO2 48.18 38.42 40.90 39.63 37.89 49.40 35.86
## PMS1 7.42 9.89 6.31 7.52 7.18 7.73 6.46
## HMG20B 184.92 135.45 175.40 164.24 115.25 161.33 177.07
## CALCRL 0.16 0.42 0.25 0.20 0.00 0.35 0.08
## TAF11 29.23 28.70 29.52 26.20 23.25 25.83 23.74
## ANKS1A 5.04 6.10 4.85 3.27 2.32 4.63 2.90
## AP3D1 48.18 53.71 54.82 45.73 46.87 53.59 44.53
## ZNF76 24.36 32.20 27.87 28.21 16.99 35.28 25.19
## SLC9A3R2 78.33 72.53 73.33 54.42 52.07 67.62 50.01
## NTHL1 30.92 32.26 25.95 22.83 35.75 30.00 23.38
## UHRF1BP1 5.22 4.81 4.89 3.71 3.54 4.02 2.65
## GNAI3 70.51 64.92 76.44 57.40 48.70 51.12 53.59
## IPO5 87.27 103.26 96.40 75.73 71.64 83.64 57.41
## OAT 99.12 85.99 87.08 80.53 61.63 74.53 87.69
## WDR3 28.01 33.65 25.92 32.78 21.31 35.99 25.14
## PKN2 16.95 16.79 16.51 15.05 8.10 16.13 11.67
## WDR18 47.55 53.09 49.29 34.34 50.28 47.45 31.76
## TRAM2 53.44 50.22 54.31 43.02 35.93 44.18 29.52
## NTN1 1.01 1.57 0.98 1.26 1.00 2.19 1.06
## GLP2R 0.62 5.35 1.12 0.50 0.31 0.88 0.26
## MCM10 6.88 12.27 10.01 3.43 0.45 3.35 0.81
## DGKA 14.50 18.61 11.75 14.68 5.36 19.50 11.10
## ERBB3 0.13 0.31 0.19 0.20 0.37 0.12 0.21
## ROPN1 0.11 0.00 0.09 0.22 0.03 0.22 0.30
## ANKRD44 2.88 4.97 2.11 3.22 1.12 4.43 1.84
## KARS 200.27 192.63 208.65 148.34 199.59 159.20 134.61
## ADAT1 25.04 41.95 30.08 26.26 27.51 34.58 17.67
## PDIA5 15.43 6.49 14.39 11.45 11.98 10.38 9.33
## TBC1D22B 5.63 5.57 5.77 5.39 3.29 5.57 4.31
## NDUFB4 291.15 328.84 295.87 317.30 215.25 325.95 369.90
## SPEN 17.60 15.81 17.97 13.09 9.83 16.02 13.05
## MYLK 261.77 145.17 188.32 294.16 91.14 299.38 164.56
## ZC3H15 34.22 46.92 37.61 37.35 29.69 36.25 40.83
## MAP2K4 18.49 20.77 22.36 21.35 12.90 18.60 18.36
## TMEM206 11.44 9.76 11.40 10.75 9.08 10.67 13.02
## SNAP91 0.00 0.00 0.00 0.00 0.00 0.00 0.04
## SLK 9.65 10.39 10.46 11.71 6.30 11.98 10.37
## CYB5R4 8.01 12.13 9.81 12.38 6.20 9.86 13.78
## COL17A1 0.18 0.25 0.28 0.30 1.24 0.36 0.49
## GSTO2 0.52 0.17 0.35 0.20 0.95 0.13 0.26
## SEC61A2 5.25 6.15 4.98 5.88 5.46 5.81 4.55
## PRKCQ 0.02 0.05 0.07 0.00 0.03 0.00 0.01
## TLE2 5.00 8.69 6.72 3.89 2.69 5.13 3.23
## ASB1 30.37 24.58 28.66 24.54 31.36 23.16 29.22
## FAM107B 72.72 38.27 73.86 44.52 37.99 33.15 26.89
## ME1 1.35 3.86 2.03 3.18 1.22 3.80 3.43
## TBC1D1 31.90 51.31 42.89 30.93 22.51 30.13 23.29
## CDK13 14.93 17.31 18.96 15.94 6.38 16.48 14.08
## MTHFD2 79.52 74.43 93.84 42.71 76.01 46.30 53.29
## SLC9A7 14.65 10.69 15.32 12.11 19.58 11.18 3.86
## FOXJ2 13.82 14.51 15.84 14.40 11.42 14.89 11.38
## YBX1 1044.66 1350.72 1102.31 1007.58 891.87 889.38 1105.32
## PDE4A 13.86 14.33 16.08 10.27 4.35 13.37 7.66
## PPP2R5A 19.47 16.43 18.91 18.31 17.90 16.37 16.93
## CTNNA2 0.00 0.00 0.08 0.00 0.00 0.00 0.01
## ELAVL1 56.94 74.88 65.00 45.27 36.78 52.22 37.95
## TIE1 4.58 2.32 3.63 7.63 6.61 4.42 5.50
## DIP2B 6.65 7.70 6.43 8.26 4.60 8.35 6.23
## SMARCD1 27.24 37.50 29.59 26.86 15.72 33.05 17.87
## KDM4A 23.70 33.74 24.64 24.98 12.34 29.70 20.41
## NFYC 38.39 51.88 36.74 32.52 59.37 43.75 33.12
## ZMYND12 0.02 0.02 0.04 0.02 0.10 0.03 0.00
## SLC9A3 1.06 1.48 1.27 1.15 0.60 2.22 0.98
## NGEF 1.05 1.39 1.88 1.01 1.96 0.91 0.45
## ASPM 8.42 16.59 11.74 6.13 2.07 13.93 3.89
## CD84 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ELOVL1 133.29 166.64 153.50 145.67 117.60 131.75 130.88
## SPI1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZNRD1 38.64 29.84 31.71 40.37 86.17 37.53 42.80
## MPPED2 16.39 9.59 8.46 7.68 7.03 8.23 5.52
## CLDN18 0.02 0.07 0.03 0.00 0.01 0.07 0.02
## ZBTB11 7.23 7.25 7.94 6.46 5.68 7.11 5.95
## ATXN3 8.68 7.45 7.14 7.20 9.39 8.66 6.66
## GOLGA5 23.70 16.84 23.69 17.58 15.07 17.97 20.31
## FGFR2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## LRRC40 18.21 17.23 21.04 15.36 9.85 14.44 13.92
## ISOC1 15.72 19.12 13.24 9.45 8.19 12.08 9.39
## EML1 16.61 11.65 27.18 20.28 13.11 13.69 13.88
## TRMT11 12.54 10.01 9.47 8.50 12.97 10.20 8.10
## THUMPD1 19.28 20.28 20.60 17.16 11.23 18.20 15.12
## MSANTD3 52.92 35.41 55.21 51.42 50.26 36.12 54.02
## KIF26A 0.06 0.00 0.02 0.02 0.00 0.01 0.00
## ATG2B 3.36 3.95 3.14 4.37 2.26 4.41 3.29
## ARFGEF1 26.36 25.69 22.50 21.30 15.67 23.97 23.79
## ACSM2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZFAT 2.45 5.11 3.87 3.74 1.92 3.50 2.15
## MTFR1 21.28 21.58 25.10 21.79 16.23 21.15 21.53
## STAG3 0.88 1.92 1.08 0.79 0.72 1.99 0.56
## FECH 22.09 28.45 18.00 31.75 23.42 37.15 25.26
## MYO9A 4.84 5.30 6.24 5.87 3.01 5.65 3.80
## DDX3Y 4.36 7.42 5.78 2.75 1.80 4.29 1.44
## PFKP 166.32 112.69 186.69 132.17 182.43 125.97 112.94
## IDI1 18.33 21.18 17.27 25.94 11.06 17.42 53.76
## SP100 97.03 64.50 81.87 87.74 101.53 84.52 94.11
## KLF6 20.03 18.51 19.67 13.80 10.25 16.47 9.90
## PPAP2A 71.44 228.03 77.46 72.45 46.53 158.65 52.30
## NEO1 15.87 27.51 16.70 11.73 7.97 24.44 6.03
## TRAM1 242.99 208.05 298.33 213.81 127.62 181.26 156.65
## PHKA1 2.23 2.94 2.35 2.99 1.68 2.56 2.61
## TNFRSF1A 167.99 185.45 149.57 229.72 139.08 274.60 280.95
## CACNB1 4.34 4.95 4.56 5.95 4.38 6.98 5.72
## EVI5 8.40 7.95 8.21 8.49 4.05 8.74 6.56
## STOML1 9.32 9.01 7.35 9.01 19.37 10.61 9.14
## PKM 2951.88 3563.11 3272.38 3476.89 1828.33 3610.93 3171.12
## DHX29 21.59 24.05 23.31 19.50 12.89 20.64 17.16
## DNTTIP2 65.41 57.84 72.02 85.80 54.71 72.36 100.89
## METTL22 31.88 25.39 28.47 25.69 32.58 28.64 21.51
## TP53BP1 15.86 20.18 14.73 15.80 11.93 18.12 11.93
## TRO 11.18 12.55 15.34 11.56 8.09 16.07 6.54
## RRP15 9.29 14.22 10.19 9.66 10.25 11.94 7.85
## RHOA 388.19 378.11 427.17 329.81 284.87 299.89 305.97
## DHX8 31.10 40.75 29.60 27.75 23.11 37.31 25.45
## PRKCZ 0.50 1.21 0.65 1.07 1.06 0.97 0.70
## ZFY 3.95 5.65 5.56 4.51 1.73 5.23 3.64
## IARS2 74.55 73.35 71.26 79.11 43.67 80.98 72.14
## SYT1 0.10 0.03 0.06 0.00 0.07 0.01 0.01
## NAV3 7.48 2.63 8.89 5.43 3.41 3.37 5.18
## IDH3G 107.63 118.02 105.88 112.32 104.88 106.23 93.47
## ROGDI 26.39 31.02 16.44 21.83 25.05 28.28 19.49
## PDZD4 17.07 20.10 19.96 15.07 9.31 17.29 13.17
## ATP2B3 0.00 0.00 0.00 0.00 0.03 0.00 0.00
## ROCK1 13.76 13.70 14.37 13.04 7.52 12.43 9.78
## CBFB 65.13 80.03 70.72 63.03 43.81 61.00 45.97
## PDK3 7.33 8.28 11.61 7.44 8.94 6.41 5.54
## HYAL2 25.17 34.06 26.25 29.74 13.15 36.24 24.13
## HDAC4 5.09 9.71 7.11 6.23 3.92 8.66 3.55
## RASSF1 17.63 13.97 22.98 13.07 11.63 12.37 11.67
## FGFR3 2.71 4.55 3.35 2.51 2.03 2.41 1.65
## IFI35 62.89 57.15 40.17 41.70 97.74 47.68 33.27
## HEATR6 9.99 10.41 8.93 5.77 8.89 8.26 5.86
## COASY 98.67 118.79 95.50 67.22 83.13 97.04 61.79
## PLEKHH3 17.38 19.84 16.63 13.68 8.03 16.30 14.58
## MEF2A 26.52 18.17 30.27 20.65 16.78 22.03 13.13
## OTUD5 58.57 48.73 55.57 45.69 43.50 50.02 44.14
## TFE3 39.72 46.26 42.91 38.69 35.25 42.81 37.01
## TBC1D25 7.95 7.33 8.13 6.68 6.29 7.61 6.71
## ACSL4 35.62 40.76 31.60 30.33 18.49 31.79 28.82
## INPP5A 10.11 9.78 11.40 8.21 7.12 7.91 9.21
## GPKOW 24.01 24.49 27.34 21.61 23.47 23.52 20.98
## GRIPAP1 14.19 15.88 11.42 11.90 11.15 16.51 11.33
## FTSJ1 53.09 37.49 57.24 37.58 38.58 34.30 28.81
## PRR11 33.48 45.74 39.69 21.10 19.38 28.15 9.01
## REEP1 2.14 5.26 2.78 3.35 0.55 4.24 2.14
## ATP11A 8.80 11.46 8.43 7.89 3.75 10.08 4.10
## POLR1A 4.90 8.56 4.96 5.79 4.52 7.75 4.01
## LAPTM4A 240.15 194.50 206.37 247.65 267.99 240.48 288.78
## TTC7A 10.96 6.54 9.76 5.90 7.59 6.71 4.54
## IP6K2 54.78 69.07 51.78 61.21 44.02 75.41 63.89
## STON1-GTF2A1L 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SRBD1 5.47 8.48 5.07 5.72 2.60 6.79 5.14
## CYFIP1 70.97 55.87 64.79 54.39 40.19 54.13 39.44
## KIF2A 24.83 33.50 31.06 23.16 15.61 23.54 14.45
## RASGRP2 0.16 0.40 0.12 0.00 0.13 0.08 0.00
## PSME4 28.43 32.39 31.51 30.83 14.52 33.87 39.76
## IFT80 22.41 21.18 18.73 20.93 15.54 28.31 22.03
## SIRT2 41.82 38.35 43.12 50.16 48.97 42.33 51.55
## ERLEC1 69.14 49.16 69.07 60.54 62.19 55.95 58.64
## PPP2R5B 14.59 16.64 16.27 10.34 7.81 12.07 8.83
## PYGM 0.20 0.02 0.18 0.03 0.06 0.02 0.11
## PAGE1 0.54 0.74 0.44 0.12 0.68 0.23 0.45
## PITX1 60.97 64.75 58.04 36.76 24.62 43.27 27.84
## TRPC7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MAST4 0.11 0.08 0.28 0.07 0.16 0.06 0.03
## GPR116 0.01 0.07 0.02 0.01 0.00 0.01 0.00
## SDK2 0.04 0.07 0.03 0.07 0.10 0.07 0.06
## ADAM7 0.00 0.00 0.01 0.00 0.00 0.00 0.01
## NUP133 17.75 19.84 16.45 14.76 15.39 17.28 12.87
## NUCKS1 144.08 187.16 173.36 104.29 140.03 142.25 79.17
## VPS35 58.89 57.11 60.07 59.58 53.00 57.69 55.62
## DNAJA2 67.48 77.33 71.78 62.58 59.13 70.61 64.94
## BCL3 48.19 54.24 37.87 56.56 40.93 83.54 67.97
## KCNAB2 17.49 21.31 17.76 24.21 14.79 25.53 21.34
## ABCC9 0.00 0.00 0.01 0.01 0.00 0.00 0.00
## GAL 0.00 0.15 0.34 0.05 0.12 0.03 0.04
## CLEC2D 1.34 1.91 1.21 2.19 1.40 2.39 2.23
## FUNDC1 7.43 8.95 7.88 6.79 7.03 7.23 8.43
## MAOB 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RORA 0.81 0.21 0.41 0.22 0.49 0.27 0.11
## DRD4 0.85 0.03 0.31 0.39 1.71 0.68 0.36
## TGFBR3 1.58 2.98 2.32 2.19 1.72 2.21 2.26
## KIAA1107 0.99 0.83 0.51 1.11 0.31 0.94 1.07
## PLA2G10 0.08 0.00 0.08 0.00 0.00 0.00 0.09
## HES2 0.12 0.39 0.18 0.16 0.15 0.06 0.04
## ATP1B3 135.71 239.79 192.50 139.45 67.23 139.44 146.68
## NEDD4 24.65 21.78 25.30 18.50 10.95 18.23 14.42
## PIGB 9.02 9.07 9.45 8.13 9.19 9.13 8.33
## MAPK6 24.76 26.54 30.42 44.13 24.77 33.12 42.21
## GNB5 23.35 26.18 23.10 23.93 19.67 24.06 18.69
## RAB27A 33.75 33.76 36.03 33.18 24.69 32.23 25.74
## CECR5 41.83 42.66 45.68 40.45 33.07 46.50 34.85
## UFD1L 84.97 125.72 99.99 161.18 69.75 107.27 219.12
## LRP6 5.18 6.38 5.51 4.79 2.24 5.87 3.57
## GUCY2C 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## SCT 0.33 0.00 0.00 0.31 0.13 0.00 0.00
## PHRF1 22.17 26.92 19.97 22.25 13.86 26.98 19.87
## IKBKAP 12.47 13.54 10.81 11.17 7.54 12.72 8.62
## NUCB2 211.58 158.19 220.96 195.43 148.93 179.61 201.88
## PFN2 362.92 297.73 356.74 351.65 179.87 300.56 423.80
## PTPN3 0.00 0.01 0.01 0.00 0.00 0.00 0.00
## SPTB 0.11 0.06 0.10 0.03 0.06 0.02 0.01
## DAPP1 0.00 0.00 0.04 0.01 0.00 0.00 0.00
## FGF10 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SLC44A1 9.79 11.55 12.02 10.23 6.49 10.12 8.30
## TMEM260 2.62 2.42 3.14 2.55 3.58 3.29 3.44
## SMG6 28.17 24.05 24.56 24.37 38.34 23.03 23.50
## EXOC5 13.45 17.80 14.84 11.41 7.69 12.26 9.51
## CLTCL1 4.11 4.06 3.68 5.17 2.64 5.23 5.53
## FGF22 0.41 0.21 0.08 0.63 0.34 1.08 0.58
## FSTL3 17.67 12.57 18.37 12.51 12.68 12.39 11.27
## DGCR2 40.73 43.33 38.34 43.24 32.36 47.36 35.20
## RNF126 49.11 50.90 52.19 33.93 31.11 41.07 36.91
## MNT 9.52 10.04 8.10 14.22 12.12 14.75 12.32
## ZXDC 9.16 10.72 10.18 7.64 5.40 9.85 7.96
## JMJD6 32.52 31.00 33.72 29.23 19.97 25.04 31.74
## POLB 25.55 29.55 22.77 19.75 32.21 22.44 21.25
## ST6GALNAC1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## WIPI1 101.54 54.94 97.61 135.67 166.57 97.48 146.32
## FRMPD1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GBA2 26.82 27.36 26.53 22.37 21.73 26.58 18.56
## NDST1 40.20 38.86 41.77 42.86 23.72 43.19 27.94
## ASNS 54.05 37.94 56.27 23.61 74.98 29.46 35.56
## AP3M2 15.12 8.73 14.19 10.55 13.99 9.33 7.04
## CNGB1 0.11 0.78 0.14 0.18 0.10 0.19 0.17
## ST6GALNAC2 7.46 6.59 9.35 6.96 13.09 4.82 4.62
## CHAT 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PABPC1 1048.17 895.86 1044.08 942.64 1143.63 1051.35 898.53
## TESK2 2.09 2.15 1.76 1.08 0.64 1.52 1.17
## C16orf80 31.50 31.12 33.31 28.48 23.45 30.08 28.81
## CSNK2A2 61.54 60.09 70.65 60.64 66.03 61.62 56.26
## PTPN21 3.05 2.87 3.06 2.54 0.95 2.07 1.51
## EIF2B3 47.35 54.04 44.10 40.13 45.77 42.36 42.71
## CAMK2A 0.00 0.01 0.01 0.02 0.00 0.06 0.08
## TCOF1 33.27 49.81 37.66 22.58 13.02 33.77 23.53
## CDC42 211.52 208.13 240.19 201.31 134.90 162.83 182.97
## OSBPL3 7.23 8.66 7.16 3.67 4.86 4.51 2.76
## EPHA8 0.02 0.00 0.04 0.00 0.00 0.03 0.00
## SLC12A3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RAD18 9.17 12.27 10.55 6.69 5.71 7.47 4.58
## ATP2B1 9.37 17.38 14.23 15.35 6.67 16.43 13.84
## TRPM5 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## NCK2 40.79 39.12 41.81 37.25 19.86 36.59 30.04
## MAP4K4 87.29 67.43 100.16 76.89 40.97 65.59 51.37
## MGAT4A 0.22 0.39 0.59 0.07 0.26 0.04 0.09
## RPL31 2259.24 1884.19 1987.47 1873.76 2794.14 1528.72 1990.67
## WDR1 165.13 138.41 180.75 113.26 135.27 95.01 84.51
## SNX13 13.03 14.51 13.28 19.63 11.98 17.01 14.76
## MS4A12 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ARHGAP10 8.99 8.54 9.70 9.28 7.66 8.10 7.44
## RPS6KA2 9.58 4.73 7.61 6.61 8.11 6.16 5.39
## ING3 5.73 10.96 7.74 6.32 6.50 6.67 5.73
## VASH1 2.65 4.34 2.83 2.75 0.69 3.22 1.90
## LMCD1 2.62 2.28 2.23 0.76 0.98 0.75 0.66
## WBSCR22 96.46 90.39 96.99 98.58 92.46 94.20 103.59
## SEL1L 13.84 13.15 15.90 15.59 9.04 15.42 14.57
## TRIP13 25.93 29.03 29.67 13.94 10.04 14.85 7.19
## ATP6AP1 92.59 98.21 93.25 104.10 81.07 118.56 112.69
## TCF3 77.00 82.83 88.15 51.51 37.63 65.45 45.50
## TRIB2 19.40 48.38 24.85 20.71 8.58 28.87 12.64
## DAZAP1 93.42 107.13 123.56 98.65 105.62 99.08 106.91
## MBD3 47.81 87.84 60.27 43.88 19.31 59.82 36.56
## PRLH 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## HLTF 40.24 46.63 35.78 26.95 19.71 29.26 21.36
## FAM50A 165.60 160.50 180.09 148.37 122.54 143.95 167.83
## FAM3A 61.07 53.49 61.96 56.21 57.82 58.05 53.03
## CPSF1 61.50 80.45 70.26 36.88 46.64 59.93 35.24
## MYO3B 0.01 0.01 0.01 0.01 0.01 0.00 0.01
## CYBRD1 68.22 64.08 68.80 83.94 43.62 83.60 80.53
## CDH19 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PDCD2 47.84 50.98 47.14 41.95 39.71 42.44 42.87
## SLC6A15 0.00 0.03 0.00 0.01 0.00 0.00 0.00
## RDH11 29.41 35.66 29.78 41.54 14.75 35.92 60.10
## PRKACA 66.13 76.17 72.42 69.70 61.00 68.56 46.70
## LPHN1 6.06 11.08 8.46 4.12 2.19 6.74 2.44
## SPP2 0.00 0.00 0.14 0.00 0.00 0.00 0.00
## ACTN1 170.23 117.92 140.04 87.46 81.81 89.14 62.68
## ZFYVE26 2.59 2.56 2.05 2.87 1.80 3.49 2.29
## RPS6KA6 0.01 0.04 0.00 0.00 0.01 0.04 0.02
## EPN2 10.19 10.42 10.90 8.12 7.61 8.62 6.76
## PTPN18 39.87 27.53 32.12 37.11 37.92 37.50 29.41
## LIMS2 0.09 0.06 0.05 0.06 0.65 0.00 0.00
## ASIC4 1.40 0.09 1.32 0.35 1.95 0.25 0.21
## SPEG 22.56 16.49 16.84 19.10 11.90 24.64 20.94
## LNX1 0.64 0.99 0.97 0.26 0.31 0.50 0.62
## ALDH3A2 162.19 200.78 162.13 151.18 90.64 232.96 120.25
## TFRC 89.27 113.66 125.18 110.64 42.38 87.98 97.20
## SREBF1 35.47 27.08 32.65 57.12 50.81 51.90 75.05
## TRPC5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## AFF4 21.63 24.32 24.97 23.53 11.69 23.98 19.40
## UBE2D1 13.56 15.64 16.63 15.15 8.55 14.18 24.08
## MPP5 12.57 10.05 13.50 9.57 5.99 8.32 8.85
## RHOBTB1 7.44 8.74 6.72 6.52 2.94 8.70 3.96
## SMC1A 17.04 34.95 21.66 12.51 4.96 18.26 6.63
## HSD17B10 67.93 73.12 62.35 81.50 66.45 79.26 95.77
## MARK2 12.50 17.67 14.68 11.50 6.92 13.81 8.08
## HMMR 20.71 41.38 27.27 14.34 12.71 28.28 11.47
## CHFR 8.43 7.82 7.79 5.53 6.25 7.54 4.70
## TRHDE 3.42 4.58 5.21 2.37 1.90 2.54 1.63
## P4HA2 195.13 85.07 256.97 179.87 135.40 133.72 111.98
## FCGR2B 0.00 0.00 0.01 0.01 0.01 0.00 0.00
## NFATC3 10.47 17.41 13.82 9.89 6.43 11.87 7.64
## TRNT1 11.06 13.78 10.13 9.71 9.71 11.47 9.63
## ACADVL 387.90 544.26 413.72 323.28 289.13 434.95 259.05
## STK10 13.56 17.51 17.22 13.70 11.65 15.20 11.83
## FBXW11 39.99 46.07 44.34 37.87 25.59 37.82 26.95
## ACAP1 6.67 2.27 7.65 7.71 10.06 4.95 7.42
## CRMP1 32.91 31.70 34.67 24.20 23.38 30.70 21.04
## EVC 11.13 10.54 11.25 10.11 6.38 12.02 6.32
## DERL2 77.46 73.45 84.64 84.46 79.04 60.88 91.73
## SIDT1 0.16 0.00 0.02 0.00 0.09 0.12 0.00
## NDE1 37.33 37.72 41.14 27.30 42.08 30.56 21.78
## MRVI1 0.76 1.02 0.62 0.22 0.10 0.58 0.09
## TMEM38A 6.56 12.96 7.11 4.35 2.22 5.66 2.88
## AP1M1 63.19 55.33 70.96 46.31 41.61 45.85 36.17
## PVR 20.28 22.80 17.73 17.47 27.18 19.16 13.95
## IKBKG 35.81 45.22 33.39 36.66 30.01 42.44 35.78
## XRCC1 36.22 41.67 39.73 19.86 16.33 25.24 16.70
## SCARB1 34.29 26.31 35.84 25.24 22.42 28.13 17.94
## CYP2W1 0.00 0.00 0.03 0.08 0.02 0.00 0.00
## MCM2 45.25 62.25 46.79 28.35 22.23 29.11 15.98
## MOV10L1 2.07 2.04 1.36 0.98 1.47 2.09 0.61
## PANX2 33.41 26.12 30.49 43.74 33.32 39.04 38.50
## SELO 26.84 30.65 26.47 22.82 17.79 29.52 27.09
## TP63 0.08 0.06 0.04 0.03 0.05 0.04 0.00
## ALPK1 6.00 5.45 4.88 5.71 6.18 6.65 4.04
## LLGL2 2.45 3.67 2.12 1.56 1.41 2.45 1.24
## PDE8A 18.77 22.31 23.45 17.74 7.51 19.80 14.03
## CLCN4 0.70 0.97 0.70 0.90 2.11 1.31 0.70
## NLE1 13.25 14.85 12.69 11.00 30.79 13.76 8.88
## SDHA 194.77 185.60 189.35 158.86 179.71 182.17 124.85
## SMARCE1 207.43 204.73 212.41 206.86 163.69 215.30 178.88
## FNDC8 0.03 0.00 0.03 0.03 0.25 0.08 0.05
## GSDMB 3.01 3.25 4.28 1.72 2.15 3.60 1.73
## KDM5A 11.05 12.49 13.33 12.28 9.06 12.54 8.70
## ADAM11 1.16 1.16 1.21 1.82 1.51 1.78 1.15
## PPP2R3A 3.97 3.77 4.04 4.27 2.23 4.52 4.03
## FERMT2 18.79 14.01 16.39 12.67 12.99 10.71 12.74
## ABCB11 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DHRS9 0.00 0.19 0.00 0.00 0.00 0.03 0.00
## CD5L 0.08 0.05 0.06 0.03 0.12 0.09 0.01
## PTGS2 0.43 1.41 0.27 0.26 0.22 0.39 0.17
## IGF2BP2 22.34 19.12 23.48 15.58 9.77 19.34 12.52
## MAP3K13 30.63 23.32 23.87 26.56 20.52 28.55 29.34
## ST6GAL1 0.64 0.82 0.30 0.29 0.32 0.59 0.43
## TBX21 0.00 0.03 0.04 0.04 0.04 0.04 0.06
## FRY 11.93 5.92 4.16 1.64 1.87 2.62 0.86
## PICALM 117.63 96.07 117.89 88.96 70.82 81.22 62.98
## NSF 29.46 37.31 28.02 33.48 20.13 33.89 28.37
## GLI2 1.14 1.25 1.92 0.62 0.77 0.82 0.38
## CLASP1 17.98 26.15 19.09 17.41 9.13 26.46 12.18
## MRPS34 152.85 181.22 171.48 111.84 103.54 135.77 112.27
## NOTCH3 2.64 1.64 3.37 3.88 1.72 5.18 3.71
## CLNS1A 131.15 133.06 117.66 111.77 138.87 126.91 126.41
## PPP2R2C 0.37 0.45 0.63 0.81 0.34 0.63 0.69
## TEAD2 28.94 56.13 32.03 25.72 10.59 34.79 18.70
## EED 22.02 30.47 26.81 19.46 13.07 21.09 16.42
## CDHR2 0.05 0.53 0.43 0.69 0.07 0.40 0.26
## SNCB 1.54 1.41 1.24 3.81 5.33 3.57 5.17
## TSG101 86.23 84.19 86.98 82.11 100.37 69.84 78.89
## C17orf85 22.52 23.60 16.41 20.83 24.84 21.94 19.05
## ATP2A3 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## CA12 36.21 21.67 55.25 53.00 27.95 46.60 35.99
## MGLL 14.33 12.30 20.05 9.48 5.89 4.70 4.25
## NTN4 14.05 7.02 7.41 6.10 5.96 6.54 4.95
## BCS1L 50.04 65.01 51.91 57.58 57.59 63.65 57.80
## NUAK1 2.83 2.92 3.82 2.73 1.34 2.62 1.47
## DPP8 14.11 14.74 18.17 13.19 9.63 13.19 8.13
## SLC24A1 5.99 4.28 3.09 4.71 15.56 6.35 4.23
## ZNF532 17.01 33.04 20.20 16.57 9.34 24.34 10.15
## SCARF1 0.26 0.12 0.23 0.20 0.38 0.25 0.20
## LMAN1 78.56 47.98 97.49 61.54 52.68 49.39 54.40
## PTPLAD1 65.44 79.24 74.33 68.30 50.27 71.76 62.31
## IPCEF1 0.03 0.10 0.08 0.02 0.08 0.05 0.01
## ZZEF1 9.85 11.19 10.56 9.16 8.63 11.66 6.82
## NOX3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ENO1 3049.32 2753.26 3634.20 3382.34 1714.82 3163.27 2743.93
## SLC12A1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## C19orf10 245.91 155.53 255.97 241.27 213.28 187.80 244.72
## ANO8 3.02 4.06 3.28 2.32 2.54 2.75 1.55
## TUBE1 4.59 4.29 5.28 4.44 7.85 3.98 3.86
## ARHGEF10L 9.95 8.29 8.80 12.48 10.69 11.60 10.52
## TXK 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## WSCD2 0.09 0.09 0.01 0.01 0.00 0.00 0.01
## KCNQ2 0.00 0.00 0.10 0.09 0.17 0.04 0.00
## TACR2 0.35 0.40 0.48 0.69 0.17 0.38 0.36
## ACTR6 18.21 20.33 16.88 16.52 19.74 16.87 19.59
## TIPIN 10.91 18.10 13.24 11.45 10.60 11.17 11.46
## SRI 433.23 416.09 424.70 410.31 347.61 407.42 372.03
## EIF4G3 27.15 36.19 21.69 25.33 11.00 32.94 20.87
## NUP37 34.79 38.96 35.06 28.70 31.94 29.04 27.98
## SEMA3A 17.71 15.63 22.31 9.46 7.58 11.17 5.58
## GTSE1 16.54 37.42 23.33 11.23 6.70 19.43 4.22
## SEMA3C 108.54 200.95 105.97 68.55 29.07 117.94 37.07
## TTC38 26.65 36.10 30.07 21.40 18.31 27.99 18.93
## ACAT1 56.05 63.92 49.00 63.88 55.46 68.26 70.32
## GRAMD4 16.30 20.22 20.82 19.47 13.41 19.30 16.25
## CELSR1 26.17 19.27 24.10 30.85 31.04 29.30 30.65
## WNT8B 0.00 0.00 0.02 0.00 0.00 0.00 0.01
## ZNF638 46.87 53.77 43.16 41.92 27.57 56.96 46.61
## SLC25A40 17.49 26.43 22.19 18.79 17.33 17.99 13.14
## TIMM21 19.17 25.90 22.76 15.46 10.40 18.36 15.60
## ADD2 0.23 0.08 0.16 0.04 0.09 0.10 0.00
## FGF4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RASAL2 6.78 3.81 5.98 5.00 3.49 3.71 3.36
## VPS9D1 12.22 13.85 12.56 13.32 9.84 14.34 12.04
## ZNF37A 4.51 4.57 3.90 4.54 5.03 5.24 3.91
## MARK3 28.39 24.98 26.64 22.42 18.65 24.67 21.51
## SLC25A3 415.09 453.34 438.64 401.72 418.66 398.74 377.59
## FNDC3B 45.59 42.22 53.87 34.57 37.45 39.90 23.90
## FOSL2 36.31 41.34 28.43 68.56 50.76 95.30 55.34
## CACNG5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CACNG4 5.68 4.02 5.67 2.49 0.60 2.93 1.47
## FRYL 8.98 9.53 9.13 7.53 4.24 7.26 5.91
## TMEM131 17.04 17.95 19.36 18.32 12.42 20.86 13.15
## FSCN1 174.65 75.63 175.94 95.45 105.17 88.69 54.09
## ACTB 3492.61 2528.04 2861.49 1772.91 2015.49 1599.36 1530.51
## MOCOS 0.58 0.76 0.82 0.31 0.35 0.67 0.21
## PLD1 3.09 3.21 3.26 1.50 5.55 2.66 1.71
## ATP12A 0.02 0.15 0.01 0.06 0.00 0.06 0.00
## WDR62 5.10 11.10 7.84 2.92 1.17 3.96 1.47
## DLG1 34.72 33.90 38.07 26.31 22.89 30.70 18.90
## RAB7A 167.64 167.32 166.74 204.90 176.26 193.93 228.63
## BCAP29 49.13 60.34 57.94 47.48 25.56 45.31 41.97
## SEC31B 2.33 3.61 2.10 2.03 1.61 4.57 2.37
## SART3 19.99 21.18 17.67 17.78 16.40 17.90 14.99
## ARHGAP15 0.00 0.39 0.21 0.03 0.02 0.09 0.09
## TUBA3D 0.00 0.07 0.09 0.09 0.00 0.07 0.00
## PAX2 0.53 1.67 0.83 0.94 0.42 1.24 0.81
## EXOSC7 40.86 30.66 38.13 34.40 55.45 39.59 37.14
## KIFAP3 20.09 15.29 16.82 21.02 18.28 18.85 21.47
## MKRN2 23.48 19.86 23.08 23.35 27.87 22.43 21.78
## MCM6 37.03 44.22 37.28 21.53 16.83 19.91 16.59
## REXO2 87.78 109.78 89.12 104.80 60.64 102.25 137.09
## RBM7 29.40 29.81 30.84 28.37 37.38 28.78 22.53
## RBMS2 6.83 7.08 4.90 3.75 2.94 4.44 2.14
## BAZ2A 17.71 20.33 21.49 18.14 9.74 22.12 11.82
## PTPN23 23.32 23.86 25.85 28.46 20.00 30.32 22.43
## MLH1 19.44 25.89 20.65 20.82 28.72 20.99 18.55
## UNG 39.57 49.28 44.29 21.96 12.65 23.66 16.96
## FMO4 2.26 2.19 1.35 4.03 4.68 2.93 3.62
## KLHL20 11.90 10.86 10.57 11.27 9.87 11.83 8.64
## RGS11 0.34 0.47 0.23 0.39 0.46 0.57 0.40
## SLC46A1 8.65 13.78 9.05 8.21 7.25 13.58 9.82
## PLXNA2 4.79 10.38 7.21 1.89 0.80 3.51 0.79
## SPAG5 18.39 37.63 25.30 10.34 7.05 18.29 4.46
## ANKRD13A 43.04 29.08 45.28 22.73 30.13 22.01 13.51
## TPD52 25.86 17.70 34.82 15.98 14.24 12.52 13.77
## ACACB 1.09 1.69 1.15 0.89 1.18 1.11 0.74
## TRAF4 32.43 44.21 34.44 24.64 25.14 28.71 19.78
## PAG1 4.18 2.51 3.32 4.09 1.93 3.05 1.90
## GPATCH1 5.86 6.79 6.47 5.17 3.98 6.25 5.79
## ICAM3 24.76 22.92 25.47 25.84 15.93 22.74 23.71
## NT5C2 45.31 41.99 48.42 52.19 44.49 49.22 44.07
## MCAM 7.26 10.23 7.16 5.73 5.62 5.97 6.30
## GPC4 1.13 1.08 0.88 0.60 0.92 1.01 0.39
## MBNL3 0.57 1.43 0.98 0.81 0.60 0.99 0.45
## CAMSAP3 0.21 0.01 0.02 0.00 0.01 0.00 0.00
## RAP1GAP 3.96 6.25 4.93 10.91 6.05 10.42 10.12
## XAB2 36.94 29.01 35.44 30.64 52.77 33.08 28.56
## ARHGEF1 66.41 70.02 68.32 58.30 32.90 66.65 57.94
## STXBP2 1.39 0.28 0.78 0.25 0.38 0.10 0.22
## MAP2K7 15.32 17.96 17.99 17.03 12.41 20.69 13.97
## NMRK2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DGKD 64.78 71.92 60.99 52.61 36.72 73.52 37.54
## CTTNBP2 0.13 0.67 0.20 0.07 0.02 0.33 0.10
## ACTL6B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RARB 52.67 53.56 58.32 47.24 23.39 47.89 31.92
## TOP2B 44.20 43.42 37.34 36.68 25.58 44.44 43.72
## TM9SF3 53.70 64.90 68.98 58.60 31.74 55.90 45.53
## NFKB2 32.47 12.29 23.95 15.63 36.51 14.21 13.59
## UBE2T 56.13 83.64 68.81 28.27 20.89 39.35 18.87
## PPP1R12B 2.75 4.30 2.47 2.65 1.61 2.82 1.95
## DNAJC10 20.39 23.67 23.24 20.51 16.02 21.99 16.18
## GTF3C1 55.67 61.30 46.14 49.58 40.43 61.49 52.70
## IL4R 30.86 26.39 23.26 16.28 26.88 22.37 10.17
## USP33 34.04 44.44 35.34 39.52 22.77 41.84 41.53
## PAK3 0.00 0.07 0.04 0.00 0.00 0.00 0.03
## CAPN6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DCX 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SNRPA 69.63 76.52 74.24 52.66 71.32 63.85 50.17
## SPAG6 0.00 0.00 0.08 0.00 0.00 0.01 0.00
## EXOSC5 36.05 34.63 31.52 37.01 52.90 41.77 40.17
## DYNC1I2 64.61 73.03 70.12 58.52 55.73 63.12 53.24
## APBB1IP 0.00 0.00 0.00 0.00 0.02 0.00 0.00
## LRCH4 16.37 22.13 18.24 14.93 13.62 20.67 12.08
## FAM76B 9.54 12.15 11.85 15.21 11.47 16.13 11.02
## SIRT6 24.03 23.54 23.96 30.33 32.01 26.39 32.17
## TYR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## POLD3 20.92 29.58 25.41 13.52 10.04 16.20 8.85
## ACTN2 0.05 0.00 0.00 0.00 0.00 0.00 0.00
## CAPZB 361.03 292.19 305.81 320.60 273.37 309.97 312.42
## GPR137B 14.90 12.91 11.97 21.45 13.62 15.99 20.09
## NAALAD2 0.18 0.31 0.23 0.21 0.03 0.27 0.38
## JADE1 7.23 7.63 7.19 5.49 7.69 7.76 5.41
## SLC25A43 21.36 17.00 22.05 17.11 10.23 17.01 15.22
## UBE2A 90.96 100.01 97.90 94.24 74.44 84.17 103.68
## FGFR1 48.25 28.14 44.39 26.48 32.08 26.02 18.64
## FKBP6 0.03 0.03 0.20 0.13 0.18 0.02 0.04
## GTF2I 107.36 163.73 114.63 99.64 47.63 134.95 76.80
## SMC1B 0.01 0.00 0.00 0.00 0.00 0.00 0.00
## FBLN1 31.46 27.48 27.98 30.82 29.67 29.76 25.86
## ITGA8 15.87 27.01 10.92 6.83 2.45 16.67 6.17
## CST7 23.95 16.39 20.90 23.98 30.51 16.71 25.74
## MAP2 1.98 0.93 1.36 3.72 0.76 2.73 4.10
## PIAS2 10.73 14.05 12.16 12.09 7.44 13.82 9.23
## AMPH 0.97 1.73 0.97 1.15 1.59 1.19 0.80
## ARAF 28.32 33.26 28.09 23.27 36.53 28.55 18.17
## MCCC1 19.21 21.62 16.75 21.76 10.29 22.69 23.36
## LAMP3 0.03 0.00 0.00 0.01 0.02 0.04 0.02
## FAP 16.77 7.75 13.16 15.74 7.79 11.38 20.71
## NEBL 0.03 0.05 0.07 0.08 0.12 0.16 0.02
## ACER3 8.11 13.65 10.28 7.24 5.13 9.66 5.85
## UBE2K 47.14 52.36 48.29 47.66 17.94 43.90 55.96
## PIK3C3 29.16 29.32 28.27 36.97 23.66 37.73 32.83
## N4BP2 0.97 1.19 1.00 1.02 0.67 1.15 0.67
## C12orf5 5.81 12.10 8.97 5.32 4.16 5.74 4.54
## TULP3 31.22 27.26 33.32 27.24 21.87 23.94 22.62
## SYNJ2 51.68 51.45 57.71 70.68 38.30 65.56 51.11
## ADCY2 0.01 0.06 0.03 0.00 0.01 0.00 0.00
## PPP2R5C 47.53 57.32 52.24 53.37 63.09 48.70 51.64
## RBFOX1 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## GNB1 309.42 303.85 333.46 231.33 185.37 237.12 191.34
## HOXA9 0.13 0.08 0.10 0.00 0.04 0.02 0.00
## EDN1 1.06 0.70 0.57 0.28 0.30 0.35 0.16
## MLLT10 6.51 7.65 7.40 6.60 5.15 8.18 7.89
## ZCWPW1 2.61 4.28 3.96 4.62 2.49 4.28 5.01
## ADCYAP1R1 0.08 0.01 0.02 0.05 0.34 0.05 0.05
## FGF20 0.00 0.00 0.02 0.00 0.00 0.00 0.00
## P2RY10 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ITM2A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NRD1 126.74 150.23 124.37 136.67 103.55 144.14 150.58
## VDAC3 124.49 170.20 161.32 146.97 94.86 134.65 145.01
## PCM1 54.89 51.88 49.58 55.25 46.25 53.47 50.70
## TNRC6C 3.03 4.83 3.19 2.29 1.32 3.68 1.74
## CBFA2T2 9.75 9.23 8.82 11.20 8.54 12.06 9.84
## BRINP1 0.02 0.04 0.01 0.17 0.00 0.01 0.03
## ITCH 30.08 26.09 35.19 26.66 15.83 22.47 17.87
## PKD2L2 0.02 0.02 0.06 0.00 0.01 0.00 0.00
## TP53INP2 13.44 12.27 9.42 16.51 12.52 15.26 17.22
## SDF4 185.35 171.19 177.52 202.97 173.66 205.85 231.38
## MYH7B 0.11 0.30 0.38 0.23 0.36 0.29 0.20
## BPIFB2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TP73 3.08 3.71 3.84 1.63 0.46 1.62 0.60
## TOLLIP 72.58 58.38 69.01 70.70 84.40 63.21 77.86
## UBE2D4 14.53 14.71 12.63 16.29 14.15 11.28 15.00
## CLUL1 0.06 0.18 0.06 0.14 0.21 0.36 0.05
## RUNX1T1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CDH17 0.08 0.01 0.04 0.02 0.05 0.02 0.04
## THOC1 10.37 17.65 13.44 14.24 9.16 16.36 13.15
## FKBP7 148.26 134.40 139.82 172.06 115.37 155.38 175.71
## OSBPL6 2.26 3.21 3.39 2.62 1.93 2.47 1.45
## SLC1A3 0.95 1.39 0.93 0.58 0.38 0.63 0.34
## XRCC5 218.94 313.08 216.38 180.46 138.80 214.62 141.60
## LXN 0.00 0.00 0.00 0.00 0.00 0.08 0.03
## SP140 0.32 0.63 0.31 0.61 0.90 0.50 0.33
## MKNK1 32.58 35.63 37.02 35.50 26.41 40.26 31.37
## TNS1 0.21 0.07 0.59 0.11 0.41 0.17 0.08
## REXO1 14.90 15.75 14.48 11.52 10.12 12.66 10.97
## SAR1A 68.13 58.64 80.69 54.80 44.26 50.23 49.48
## CDC14A 2.60 2.32 1.89 1.31 1.50 1.76 1.05
## RAPGEF3 2.58 2.02 2.68 0.79 1.56 0.91 0.63
## CEACAM1 0.30 0.23 0.19 0.13 0.20 0.22 0.12
## SENP1 10.62 15.44 12.38 8.68 6.64 9.64 5.60
## DUSP13 0.00 0.08 0.13 0.22 0.13 0.15 0.50
## CIC 38.29 41.04 39.75 37.44 21.60 41.81 31.16
## LIPE 1.50 2.49 1.48 1.22 1.17 1.58 1.47
## FDFT1 88.69 89.15 80.77 100.33 91.46 90.60 153.66
## PAFAH1B3 35.32 55.86 40.34 35.16 21.30 39.37 33.13
## OPHN1 1.14 2.37 1.14 1.88 1.83 1.61 0.63
## AFM 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## KIF22 49.52 75.26 58.67 38.03 36.87 56.70 26.62
## SCGN 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## LRRC16A 2.83 3.57 2.88 2.43 1.25 2.96 2.44
## PGM1 112.80 97.97 136.57 90.61 62.75 99.75 62.93
## DDX1 62.38 68.32 71.03 61.87 50.19 62.45 55.37
## DNM2 110.81 114.74 119.07 88.36 71.12 102.69 79.35
## EPB41L2 20.51 21.22 21.21 15.82 8.94 18.99 12.65
## RIMS1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MOXD1 0.98 0.49 1.03 0.68 0.59 0.44 0.51
## STX7 14.02 10.38 12.04 11.06 16.02 11.89 11.26
## RABL2B 21.79 25.31 23.42 18.52 21.63 22.60 14.52
## KEAP1 89.05 98.50 88.26 116.77 68.41 110.44 108.53
## DDX43 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PTPRH 3.69 2.33 3.59 3.65 6.66 3.76 2.38
## DCT 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## SLC35C2 99.12 76.21 92.07 92.89 97.99 94.88 77.69
## CRYBG3 7.26 10.33 8.78 9.14 5.13 10.28 9.65
## EPHA6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SCTR 0.19 0.28 0.35 0.00 0.04 0.19 0.07
## RFX3 0.65 0.79 0.51 0.93 1.04 0.90 0.68
## RIF1 5.67 7.96 6.25 4.82 2.33 5.40 2.90
## RAB21 26.83 27.30 25.72 30.86 30.33 26.00 32.93
## SLC4A4 0.10 0.55 0.20 0.10 0.02 0.14 0.04
## SMARCA2 24.87 32.85 19.83 28.23 24.01 29.03 35.13
## RDH8 0.00 0.00 0.00 0.00 0.05 0.00 0.00
## SESN1 1.10 1.95 1.76 2.23 1.61 1.92 2.07
## MID2 1.38 2.17 1.97 1.61 1.99 1.32 0.87
## PIH1D3 0.00 0.00 0.00 0.00 0.03 0.00 0.00
## COL5A3 0.29 0.04 0.11 0.33 0.99 0.20 0.20
## SRCAP 19.78 32.44 24.20 21.92 10.15 25.01 11.87
## KIAA0020 21.00 24.58 20.82 17.63 34.90 22.68 18.68
## CPB2 0.02 0.05 0.04 0.00 0.00 0.00 0.00
## CHRNA3 0.20 0.06 0.10 0.04 0.12 0.10 0.00
## KCNN2 0.00 0.00 0.00 0.00 0.00 0.00 0.04
## CNOT4 9.85 11.32 11.30 12.33 6.59 12.11 12.30
## PSEN1 19.55 18.71 19.80 20.13 15.39 20.78 15.17
## CPOX 17.49 25.74 18.76 17.22 8.51 20.67 14.98
## CLDND1 88.75 66.64 87.71 78.82 61.59 75.29 71.52
## MOK 15.44 9.85 12.38 10.18 10.12 10.54 8.73
## HSP90AA1 282.62 402.85 351.24 235.13 154.20 222.28 222.64
## RBL1 5.85 10.10 6.73 5.04 1.87 5.10 2.73
## DLGAP4 94.61 78.19 106.12 72.38 84.97 76.26 51.96
## IGSF9B 2.45 0.55 1.64 1.16 1.78 0.76 0.40
## CFHR2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NDC80 15.95 29.21 19.59 8.74 6.82 16.49 4.31
## AP4E1 3.16 4.69 3.72 3.82 2.74 4.03 3.26
## RSBN1 6.31 6.19 6.56 5.15 4.29 5.13 4.30
## MAGI3 3.47 3.05 3.87 2.59 2.74 2.66 1.56
## CXCL2 0.14 0.03 0.11 0.07 0.29 0.05 0.19
## AFP 0.24 0.48 0.22 0.50 0.19 0.08 0.67
## COL4A4 0.01 0.01 0.01 0.01 0.00 0.01 0.00
## TCF7 44.74 43.46 51.42 80.20 25.72 62.47 68.15
## OSTM1 20.49 30.95 21.57 36.62 30.32 29.88 34.02
## CDH7 0.06 0.01 0.00 0.16 0.00 0.09 0.21
## IMPG2 0.02 0.00 0.00 0.00 0.00 0.01 0.00
## PCNP 120.73 118.24 133.99 120.66 99.17 109.72 132.27
## EXD2 5.38 5.06 4.87 4.38 2.14 5.43 3.76
## ARG2 4.61 11.84 6.80 4.84 1.80 4.21 3.55
## MEF2C 0.19 0.09 0.23 0.08 0.02 0.01 0.07
## PTPRC 0.00 0.00 0.00 0.01 0.00 0.02 0.00
## CACNA1S 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PKP1 0.11 0.01 0.02 0.01 0.01 0.00 0.01
## UBA5 20.60 22.07 19.70 16.20 19.62 18.53 16.13
## STK17B 7.28 5.94 7.76 5.90 6.10 6.20 4.71
## CDC14B 14.19 15.04 14.97 19.62 14.06 19.63 15.59
## ZNF510 3.04 4.36 3.56 3.37 3.48 3.49 2.26
## LRP2 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## ZNF506 4.43 3.59 3.95 3.69 5.59 3.05 2.84
## JMJD4 13.33 16.00 10.46 10.73 17.94 14.29 9.35
## DUSP12 31.51 37.04 39.33 30.73 34.18 30.93 28.83
## AACS 13.82 15.98 12.32 10.70 10.91 13.08 7.66
## KIAA0141 55.02 57.35 55.65 55.26 51.55 62.49 47.48
## SLC13A1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CADPS2 2.76 2.74 2.71 1.02 0.63 1.06 0.48
## PCDHB4 0.27 0.29 0.16 0.27 0.29 0.36 0.32
## PCDHA6 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## PCDHGA2 0.67 0.90 0.58 0.66 0.65 0.89 0.64
## HSPB11 145.36 167.72 154.97 125.42 73.31 102.01 121.51
## PHLPP1 1.61 1.91 1.56 1.27 0.72 1.52 1.03
## ATP8B1 7.99 3.11 7.12 3.64 4.60 3.08 2.20
## IL12RB2 0.04 0.02 0.03 0.03 0.01 0.02 0.01
## SMARCD3 59.69 59.33 51.74 51.17 50.39 66.30 54.58
## WDR70 27.58 25.94 23.29 25.92 15.03 29.31 31.76
## FYB 0.62 0.59 1.17 1.73 0.24 1.07 1.40
## MPP4 0.31 0.24 0.28 0.05 0.12 0.04 0.08
## STRADB 15.99 15.46 14.78 13.37 12.76 14.14 13.20
## BZW1 142.78 133.70 152.22 140.30 141.86 122.65 114.30
## PGR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## C1QTNF3 1.69 1.41 1.91 0.66 0.71 1.38 1.02
## ME2 18.33 19.76 18.34 13.17 20.84 13.11 14.91
## C5orf22 16.56 16.10 18.49 18.40 18.78 16.27 16.08
## CCNT2 6.82 7.60 6.10 5.74 3.89 8.18 5.06
## FAM135A 1.90 2.59 2.38 2.23 1.49 2.21 2.31
## COL19A1 0.35 0.38 0.22 0.22 0.05 0.32 0.08
## EPB41L3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## COBLL1 3.81 3.85 5.00 1.93 1.45 2.53 1.17
## DLG3 4.82 5.52 4.30 3.33 2.55 3.85 1.78
## KCNK2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SERTAD4 1.49 2.93 1.89 0.51 0.07 0.80 0.36
## TRAF5 3.27 4.07 3.03 1.69 1.88 2.82 1.09
## MRPL22 90.68 84.41 90.15 85.19 86.76 78.72 94.39
## GEMIN5 12.15 16.48 10.89 12.76 8.64 14.77 9.53
## OPRK1 0.00 0.00 0.03 0.00 0.01 0.00 0.05
## NFE2L1 78.34 81.64 74.33 88.26 168.50 80.73 71.24
## SEMA5B 0.00 0.00 0.03 0.00 0.01 0.00 0.00
## GSK3B 16.77 20.22 18.80 17.34 25.40 18.41 13.49
## ITGB5 68.60 43.00 60.65 58.49 22.90 46.12 59.53
## ERC1 9.87 11.26 9.99 8.72 4.32 10.31 5.06
## XPO1 49.09 81.44 54.75 51.35 44.87 58.32 47.90
## C4orf6 0.00 0.14 0.15 0.09 0.27 0.11 0.00
## RNF13 35.74 40.44 42.11 48.03 30.94 46.28 65.56
## TRPM3 0.03 0.01 0.01 0.01 0.01 0.02 0.01
## PALB2 9.76 13.17 10.95 8.97 5.66 8.54 10.03
## DOPEY1 1.91 1.91 1.64 1.90 1.39 2.29 1.75
## LYRM2 22.11 31.73 22.75 30.20 21.19 30.89 27.29
## BCKDHB 18.72 18.13 14.69 19.65 11.13 20.35 16.43
## mRNA_R3 mRNA_R7 mRNA_R6 mRNA_R5 mRNA_R4 mRNA_R2 mRNA_R1
## TSPAN6 5.32 5.00 4.42 3.22 4.13 4.48 4.64
## TNMD 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DPM1 75.27 72.06 68.96 75.23 80.33 87.15 72.45
## SCYL3 6.71 7.07 5.51 10.49 7.89 8.51 8.67
## C1orf112 12.05 10.21 8.96 7.03 10.64 10.74 10.77
## FGR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CFH 0.02 0.09 0.01 0.00 0.02 0.05 0.03
## FUCA2 78.60 73.15 60.68 24.41 55.03 66.94 54.06
## GCLC 54.69 75.74 50.15 123.58 137.28 175.46 111.48
## NFYA 28.04 25.76 16.38 32.36 29.25 32.30 28.43
## STPG1 5.83 6.06 4.62 11.50 7.15 7.35 6.94
## NIPAL3 29.52 34.29 24.08 26.49 35.11 39.20 35.55
## LAS1L 50.95 43.42 37.91 33.80 49.30 52.31 40.89
## ENPP4 6.96 8.76 6.29 8.37 10.02 9.89 8.83
## SEMA3F 1.58 1.50 1.37 1.07 0.85 1.21 1.21
## CFTR 0.04 0.22 0.04 0.01 0.01 0.03 0.01
## ANKIB1 17.86 21.72 15.00 27.24 21.91 21.28 23.10
## CYP51A1 191.83 179.26 130.49 216.53 225.20 245.95 207.27
## KRIT1 21.57 23.56 18.32 22.82 25.57 24.97 27.98
## RAD52 10.29 9.07 7.25 12.62 9.40 8.91 11.14
## BAD 105.71 108.78 105.00 112.31 115.96 107.63 97.41
## LAP3 41.15 38.22 29.93 82.06 50.90 55.72 43.66
## CD99 32.89 34.43 34.86 29.78 39.39 37.51 42.41
## HS3ST1 0.12 0.13 0.08 0.02 0.20 0.06 0.08
## AOC1 0.70 0.52 0.40 0.77 0.43 0.53 0.41
## WNT16 0.07 0.03 0.09 0.22 0.03 0.04 0.07
## HECW1 0.02 0.00 0.01 0.07 0.03 0.01 0.03
## MAD1L1 33.40 29.37 30.41 14.95 22.23 26.93 26.44
## LASP1 112.06 89.97 75.09 215.70 133.90 144.97 116.49
## SNX11 13.51 11.12 10.53 33.89 16.49 16.91 14.87
## TMEM176A 0.05 0.00 0.00 0.00 0.00 0.00 0.00
## M6PR 82.87 80.92 68.99 81.45 89.44 98.13 76.45
## KLHL13 3.18 3.76 2.34 0.43 1.47 2.61 1.84
## CYP26B1 0.09 0.05 0.06 0.09 0.02 0.02 0.09
## ICA1 44.19 41.14 42.49 62.37 52.81 59.51 50.64
## DBNDD1 24.12 27.03 24.74 10.06 18.42 21.83 21.86
## ALS2 7.54 7.05 5.30 18.19 11.70 12.06 8.79
## CASP10 0.07 0.11 0.01 0.11 0.06 0.07 0.07
## CFLAR 11.94 10.32 8.71 20.54 10.24 11.20 11.29
## TFPI 37.25 45.74 36.42 20.26 32.60 39.16 34.04
## NDUFAF7 9.85 7.75 7.70 15.83 10.48 11.04 11.17
## RBM5 35.71 39.22 33.57 54.96 41.41 44.06 51.18
## MTMR7 1.50 1.89 1.90 3.89 2.45 2.21 1.94
## SLC7A2 9.83 12.89 8.88 4.07 9.65 11.14 12.88
## ARF5 461.15 426.62 463.04 526.03 518.55 499.52 460.74
## SARM1 30.77 32.10 24.48 12.05 25.15 29.22 24.51
## POLDIP2 108.21 108.68 96.13 147.09 115.02 120.05 100.53
## PLXND1 8.87 13.31 12.30 3.07 7.30 8.67 8.98
## AK2 215.08 202.37 162.27 146.11 192.86 227.60 167.96
## CD38 0.13 0.09 0.15 0.00 0.00 0.02 0.00
## FKBP4 344.30 304.09 249.77 296.68 376.97 390.52 297.65
## KDM1A 40.36 46.57 42.07 31.32 35.32 39.92 38.29
## RBM6 35.63 33.11 34.85 46.66 36.98 37.07 35.98
## CAMKK1 2.85 4.35 3.48 1.16 2.90 4.28 3.72
## RECQL 38.89 35.30 22.47 36.61 39.07 39.96 38.24
## CCDC132 15.22 16.74 13.06 17.99 18.08 18.35 15.68
## HSPB6 493.04 228.89 271.66 94.00 279.52 379.06 346.26
## ARHGAP33 12.26 11.67 10.86 10.96 14.46 12.33 23.52
## NDUFAB1 311.95 296.07 286.42 237.50 293.65 328.47 262.32
## PDK4 34.98 18.70 21.03 31.47 66.02 67.25 48.66
## SLC22A16 0.26 0.40 0.29 0.08 0.27 0.27 0.07
## ZMYND10 5.88 4.16 4.99 2.01 3.09 3.47 4.25
## ABCB5 0.03 0.02 0.01 0.02 0.00 0.04 0.01
## ARX 0.33 0.39 0.40 0.28 0.32 0.39 0.32
## SLC25A13 26.82 31.30 23.45 17.70 29.57 33.75 27.26
## ST7 26.91 27.70 25.26 21.87 27.69 31.07 28.80
## CDC27 31.14 31.29 22.38 37.41 28.53 34.95 29.85
## SLC4A1 0.13 0.02 0.05 0.03 0.06 0.02 0.10
## CALCR 0.02 0.00 0.00 0.02 0.02 0.06 0.05
## HCCS 37.30 34.79 30.91 46.59 37.99 42.81 29.38
## DVL2 32.67 36.64 29.34 41.78 38.65 41.15 46.15
## PRSS22 1.31 1.29 1.45 0.73 1.61 1.23 2.70
## UPF1 26.41 27.75 25.75 33.03 25.40 24.90 24.28
## SKAP2 23.43 26.32 15.64 25.52 31.60 36.60 37.08
## SLC25A5 678.12 741.28 642.78 332.20 632.49 699.99 611.07
## CCDC109B 38.66 31.07 28.40 41.55 39.22 36.99 35.45
## HOXA11 0.37 0.24 0.43 0.06 0.34 0.32 0.29
## POLR2J 184.59 173.88 181.58 158.92 174.11 179.23 158.32
## DHX33 14.49 17.79 11.49 16.20 15.18 17.09 14.55
## MEOX1 0.00 0.00 0.00 0.03 0.00 0.00 0.00
## THSD7A 0.00 0.00 0.00 0.07 0.07 0.16 0.02
## LIG3 19.51 19.93 14.34 13.72 18.83 24.18 19.18
## RPAP3 51.02 52.27 39.80 47.12 49.10 56.46 39.81
## ACSM3 31.23 37.23 40.07 23.22 29.78 31.19 45.02
## AC004381.6 48.49 39.02 34.58 23.07 35.51 38.15 38.48
## CIAPIN1 74.48 72.35 67.26 84.91 70.42 79.28 55.28
## FAM214B 18.45 18.32 18.11 50.08 36.62 31.76 34.13
## COPZ2 10.58 9.84 8.76 3.59 5.27 8.25 6.68
## PRKAR2B 10.31 14.41 8.17 2.32 5.88 8.39 9.76
## MSL3 21.53 28.43 25.49 16.08 18.78 20.02 17.99
## CREBBP 10.04 9.79 5.85 18.03 9.92 10.54 11.75
## BZRAP1 19.15 30.96 27.09 6.19 12.38 11.13 22.50
## MPO 0.08 0.11 0.05 0.03 0.03 0.03 0.02
## PON1 37.32 68.99 64.25 7.52 17.91 20.56 34.74
## GCFC2 19.42 24.16 21.59 15.98 14.71 18.43 16.57
## WDR54 42.38 42.47 43.41 11.61 26.48 31.93 39.19
## CROT 48.36 58.49 46.92 31.16 51.71 61.47 49.24
## ABCB4 0.62 0.68 0.71 0.08 0.34 0.22 0.92
## KMT2E 20.00 19.51 11.34 29.37 21.84 28.44 26.83
## RHBDD2 152.97 145.68 149.07 479.27 190.10 175.15 157.28
## SOX8 0.01 0.03 0.02 0.00 0.00 0.00 0.00
## IBTK 25.03 23.47 18.75 37.57 28.21 31.16 24.94
## ZNF195 18.02 20.00 17.68 23.46 18.59 19.13 17.90
## MYCBP2 11.10 13.01 9.17 15.20 12.47 12.88 12.29
## FBXL3 18.79 19.76 14.78 40.44 24.35 24.62 21.53
## ITGAL 0.58 0.33 0.45 0.90 0.65 0.37 0.42
## PDK2 23.80 28.78 23.09 12.39 23.62 23.50 28.06
## ITGA3 10.26 7.73 7.51 22.70 13.69 13.59 11.32
## ZFX 7.35 11.09 6.06 6.05 7.46 7.29 7.21
## LAMP2 41.52 40.45 28.60 99.36 57.70 62.96 54.36
## GGNBP2 51.01 46.81 43.79 80.23 61.38 62.11 57.26
## ITGA2B 1.75 2.43 2.27 0.32 0.22 0.37 1.62
## ASB4 0.13 0.34 0.22 0.03 0.07 0.14 0.11
## GDE1 59.31 64.72 52.28 66.05 63.06 66.84 57.71
## C19orf60 118.94 106.48 112.63 52.29 102.59 116.41 98.51
## CRLF1 9.63 8.68 8.88 7.46 9.21 7.99 11.10
## OSBPL7 0.12 0.02 0.06 0.36 0.02 0.11 0.05
## TMEM98 27.84 31.57 25.10 9.48 16.80 16.59 18.09
## YBX2 14.73 18.02 18.81 4.04 9.71 8.26 15.10
## KRT33A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ABCC8 0.58 0.75 0.54 0.37 0.50 0.17 0.67
## CCL18 0.06 0.00 0.00 0.00 0.00 0.00 0.00
## CCL3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SYNRG 11.99 9.81 7.52 22.52 13.08 13.88 12.22
## CACNG3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMEM132A 39.22 52.37 45.23 10.47 20.43 24.86 26.11
## AP2B1 81.82 64.47 51.69 107.06 98.60 102.09 97.54
## TAC1 0.00 0.00 0.00 0.04 0.00 0.00 0.00
## ZNF263 19.39 24.70 18.53 54.58 21.44 22.54 25.24
## CX3CL1 6.07 12.07 8.87 1.74 3.07 3.76 4.53
## SPATA20 79.94 85.72 86.55 57.70 75.38 78.47 79.58
## CACNA1G 0.12 0.26 0.21 0.22 0.36 0.38 0.37
## TNFRSF12A 53.34 22.05 30.64 94.28 49.59 44.41 29.27
## DLX6 0.00 0.05 0.00 0.04 0.00 0.00 0.00
## MAP3K9 3.20 3.16 2.17 6.55 4.46 4.69 4.10
## RALA 39.28 39.77 33.18 45.20 40.78 43.38 36.16
## BAIAP2L1 26.45 23.72 20.70 58.60 38.74 32.76 36.11
## KDM7A 3.47 3.09 2.77 11.50 7.06 7.47 8.36
## ETV1 11.37 7.14 4.47 16.04 14.91 14.08 12.02
## AGK 28.23 28.55 23.00 25.31 30.04 36.38 27.35
## ALDH3B1 1.33 1.69 1.47 0.39 0.83 0.78 0.97
## TTC22 0.00 0.00 0.01 0.01 0.00 0.00 0.01
## PHTF2 41.74 47.74 31.84 48.74 46.00 45.10 46.02
## CCL26 0.00 0.00 0.00 0.41 0.07 0.00 0.00
## FARP2 11.60 10.61 6.48 20.76 13.09 16.43 15.30
## USH1C 1.52 3.59 3.20 0.41 0.68 1.16 2.15
## GGCT 244.09 213.27 207.77 124.85 216.95 225.06 200.32
## DBF4 43.10 50.10 34.94 38.98 39.11 42.06 38.80
## TBXA2R 2.67 2.59 1.82 1.94 2.60 2.10 2.05
## IFRD1 31.19 23.20 24.22 137.68 59.38 38.99 42.71
## LGALS14 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## COX10 11.62 10.19 7.83 12.33 12.34 13.68 10.78
## GTF2IRD1 9.83 14.02 14.53 5.54 8.57 9.09 10.76
## PAF1 56.77 60.92 54.54 53.22 53.29 57.34 46.60
## VPS41 35.91 32.86 20.38 48.46 37.05 43.88 43.92
## ARHGAP44 1.03 1.19 0.84 0.40 0.69 0.97 1.04
## ELAC2 44.33 44.13 37.19 30.52 43.88 49.56 36.46
## SCIN 6.65 9.43 6.26 1.69 4.66 5.53 4.65
## ARSD 17.41 14.45 14.68 16.76 14.38 17.78 13.28
## PNPLA4 18.71 18.17 16.97 22.97 21.27 22.03 20.15
## MYH13 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ADIPOR2 34.58 38.32 29.13 67.70 42.68 43.77 38.24
## CDKL3 3.85 3.42 3.55 12.69 7.36 6.39 6.07
## UPP2 0.00 0.00 0.00 0.04 0.00 0.00 0.06
## PRSS21 47.60 49.54 52.89 19.29 23.68 27.49 27.59
## MARK4 7.29 8.12 6.94 11.83 8.31 9.71 10.76
## PROM1 0.01 0.01 0.01 0.00 0.00 0.00 0.00
## CCDC124 184.41 178.18 161.42 114.39 170.49 186.08 139.10
## CEACAM21 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PAFAH1B1 53.80 46.42 37.99 109.91 67.34 77.23 54.61
## NOS2 0.00 0.00 0.00 0.00 0.01 0.00 0.01
## DNAH9 0.01 0.00 0.00 0.00 0.00 0.02 0.00
## KIAA0100 42.58 50.91 35.06 40.69 42.43 47.43 41.72
## SLC13A2 0.02 0.01 0.00 0.00 0.00 0.03 0.01
## GAS7 0.00 0.00 0.01 0.02 0.00 0.00 0.00
## TRAPPC6A 77.94 92.19 93.55 63.53 71.26 70.65 84.25
## MATK 33.93 47.53 42.13 4.92 17.55 24.27 23.67
## CEACAM7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CD79B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SCN4A 0.08 0.07 0.01 0.24 0.08 0.15 0.15
## ST7L 19.67 17.35 16.38 12.67 16.27 19.69 15.46
## TKTL1 0.19 0.16 0.01 0.02 0.07 0.12 0.12
## PAX6 3.34 5.19 2.79 11.37 6.04 6.14 9.07
## RPUSD1 26.94 35.71 33.51 13.71 23.88 23.68 23.22
## RHBDF1 21.85 23.20 26.67 39.31 26.37 24.12 28.35
## LUC7L 25.95 26.00 38.10 31.37 22.49 20.22 26.02
## CACNA2D2 6.17 7.40 5.22 4.22 3.82 4.23 4.99
## BAIAP3 3.44 4.37 3.64 10.53 6.28 5.99 12.38
## TSR3 74.15 71.43 65.07 42.01 62.78 72.93 53.05
## PIGQ 24.97 32.18 31.51 12.87 16.49 18.60 21.06
## CRAMP1L 10.91 10.68 8.97 18.99 12.52 12.22 15.20
## TEAD3 4.98 6.14 6.13 6.93 5.07 5.77 5.42
## SELE 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DNAJC11 33.84 33.29 27.41 22.97 35.41 34.78 28.82
## FMO3 0.05 0.00 0.01 0.00 0.00 0.02 0.00
## MYLIP 7.55 10.14 8.13 15.98 8.40 10.28 10.08
## NOX1 0.04 0.03 0.03 0.05 0.11 0.14 0.07
## E2F2 18.02 22.31 16.07 8.86 13.89 13.61 16.53
## PSMB1 409.24 348.69 358.59 471.62 466.15 500.91 387.91
## SYN1 2.29 2.53 2.51 1.57 1.95 1.87 2.25
## JARID2 2.80 3.24 2.24 2.86 2.95 3.44 3.66
## CDKL5 0.17 0.29 0.12 0.50 0.29 0.49 0.33
## CAMK1G 0.00 0.00 0.06 0.00 0.00 0.00 0.00
## CDK11A 17.64 17.20 15.38 57.70 19.51 17.71 17.66
## NADK 42.19 53.98 42.76 71.59 56.34 49.81 51.58
## TFAP2B 0.01 0.04 0.05 0.01 0.02 0.02 0.00
## TFAP2D 0.31 0.14 0.17 0.06 0.10 0.17 0.14
## DLEC1 0.13 0.09 0.02 0.17 0.05 0.13 0.13
## CYTH3 10.91 13.21 9.93 25.05 15.61 13.63 16.39
## ADAM22 4.50 6.59 3.60 1.29 3.77 4.34 5.51
## SYPL1 47.82 43.43 37.43 62.79 62.99 66.70 47.61
## CYB561 86.55 102.33 84.95 55.40 72.11 76.18 67.44
## SPAG9 25.74 25.22 17.37 86.32 45.12 46.18 39.36
## CELSR3 20.15 25.38 27.94 19.14 19.85 19.75 25.36
## AASS 2.57 3.00 2.26 6.45 3.19 4.24 3.28
## PLEKHG6 7.28 11.05 9.04 8.97 10.05 9.73 8.98
## SS18L2 39.90 41.54 46.75 43.40 36.77 38.82 35.69
## MPND 18.73 19.99 19.94 8.31 17.19 16.31 15.15
## MGST1 359.60 317.86 292.04 457.40 550.87 564.63 362.66
## CRY1 12.26 14.04 10.19 27.49 15.84 17.54 12.03
## PGLYRP1 0.06 0.05 0.05 0.05 0.05 0.00 0.05
## NFIX 125.55 169.57 93.81 53.05 91.34 114.97 159.25
## ST3GAL1 79.76 68.78 58.07 59.37 82.47 93.97 65.72
## MMP25 0.46 0.92 0.81 1.08 0.47 0.57 0.72
## IL32 0.08 0.28 0.25 0.98 0.38 0.15 0.19
## PKD1 22.43 24.14 22.92 41.42 29.94 30.04 46.02
## MAPK8IP2 65.10 67.77 57.45 53.78 75.03 76.60 76.61
## MED24 48.62 53.83 47.72 27.51 42.38 48.05 47.59
## RHOBTB2 9.34 10.30 7.53 17.54 12.85 11.29 12.47
## HEATR5B 7.29 7.78 5.26 11.11 10.72 11.61 11.43
## SEC62 64.88 68.84 60.90 85.94 73.39 78.80 64.07
## RPS20 2245.17 2248.88 2574.22 1986.90 2036.59 1989.85 2334.32
## CSDE1 192.39 211.68 152.63 195.15 190.98 227.41 195.71
## UBE3C 51.08 54.70 39.41 54.21 55.52 63.84 48.12
## REV3L 9.82 9.04 9.26 17.14 11.03 13.30 10.16
## TENM1 0.46 0.55 0.55 0.10 0.19 0.47 0.44
## PAX7 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## MASP2 0.29 0.37 0.22 0.36 0.12 0.22 0.27
## IYD 0.13 0.02 0.01 0.00 0.00 0.06 0.04
## FAM76A 6.66 7.10 4.86 5.34 5.87 6.40 5.94
## TRAF3IP3 3.32 2.24 1.81 4.43 2.44 3.08 2.66
## POMT2 11.15 11.08 7.25 11.53 12.52 10.83 10.63
## VTA1 51.83 53.98 41.91 56.38 62.66 68.36 53.03
## MLXIPL 4.72 4.05 5.69 5.67 4.55 3.41 7.51
## BAZ1B 47.94 52.15 35.59 45.39 46.81 44.73 46.69
## RANBP9 32.38 33.28 23.60 68.43 45.13 49.59 40.30
## ETV7 1.36 1.29 1.39 4.35 1.85 1.97 1.68
## SPRTN 11.37 11.91 9.75 24.37 13.62 14.20 11.42
## METTL13 37.89 37.60 34.49 49.35 41.27 43.31 35.46
## DYRK4 30.08 29.40 28.83 8.24 13.08 20.45 18.84
## ZNF207 106.12 110.52 91.05 82.05 74.68 95.51 72.43
## UQCRC1 271.79 304.65 295.36 190.73 256.87 272.70 232.48
## STARD3NL 91.90 109.34 97.67 71.39 82.92 93.68 75.35
## CD9 240.21 311.05 262.04 158.55 212.50 216.44 231.82
## HHATL 0.00 0.04 0.00 0.42 0.05 0.05 0.05
## NCAPD2 60.67 72.06 49.15 34.99 52.02 48.87 66.01
## IFFO1 3.02 2.69 3.15 2.28 2.36 2.58 3.18
## GIPR 0.29 0.31 0.44 1.10 0.44 0.33 0.73
## PHF7 9.72 11.47 8.90 12.41 13.14 13.20 14.99
## SEMA3G 0.96 1.71 1.29 0.54 0.27 0.36 0.57
## NISCH 24.31 22.93 20.09 47.72 25.91 25.04 32.07
## STAB1 0.70 1.06 2.15 0.19 0.20 0.25 0.58
## FUZ 10.22 15.41 16.51 4.58 6.51 6.55 7.13
## SLC6A13 0.04 0.14 0.11 1.38 0.06 0.21 0.06
## IDS 29.69 22.18 17.36 72.14 43.52 46.96 35.37
## PRSS3 5.26 3.63 2.75 3.88 5.10 6.23 2.29
## ZNF200 5.98 5.65 5.21 11.86 5.96 7.40 6.62
## CD4 0.61 0.79 0.90 0.24 0.25 0.32 0.50
## LRRC23 16.19 12.91 14.52 13.78 14.59 15.64 17.31
## BTK 0.00 0.10 0.10 0.03 0.01 0.00 0.01
## HFE 0.48 0.21 0.13 0.09 0.12 0.29 0.19
## SCMH1 19.13 23.92 18.12 9.92 15.43 15.98 19.62
## FYN 3.36 3.26 1.55 3.27 2.45 2.88 3.70
## HIVEP2 3.58 4.93 2.53 7.78 3.54 4.13 4.31
## FMO1 0.10 0.08 0.00 0.02 0.00 0.17 0.00
## TCEB3 31.74 30.84 24.23 46.43 40.72 42.14 32.84
## LYPLA2 41.90 49.34 52.67 71.65 57.72 57.24 51.15
## CLCN6 2.41 2.63 2.18 3.85 3.01 4.08 3.91
## MRC2 1.41 1.31 1.14 1.03 0.73 0.89 1.36
## NME2 838.64 812.44 802.43 351.48 672.18 704.34 626.06
## SLC6A7 0.02 0.06 0.12 0.00 0.00 0.02 0.01
## TSPAN9 1.48 1.16 0.83 1.22 0.91 1.35 1.58
## BTBD7 6.99 8.43 5.92 10.42 8.36 8.80 8.08
## APBA3 10.61 9.95 10.70 17.36 13.47 11.32 11.91
## MKS1 15.11 15.38 14.50 12.09 12.41 14.44 12.05
## ABHD5 16.02 13.48 9.96 44.58 21.78 21.44 16.63
## KAL1 1.28 1.30 1.11 0.85 1.17 1.30 1.74
## AKAP8L 35.94 34.48 37.59 116.37 55.04 43.64 55.97
## MBTD1 6.66 8.76 6.83 8.37 8.67 8.23 9.46
## UTP18 43.58 49.98 44.51 23.99 45.66 48.61 39.93
## RNF216 12.22 13.70 10.81 17.66 15.84 16.16 15.72
## TTC19 55.56 54.74 47.63 36.40 43.32 54.09 41.08
## PTBP1 152.13 170.22 144.26 116.87 144.81 153.69 145.52
## DPF1 1.64 1.54 1.02 0.42 1.53 1.24 1.02
## SYT7 14.79 18.73 12.88 6.48 10.43 13.65 15.32
## LARS2 17.33 17.69 11.50 12.65 15.98 18.83 17.27
## PIK3C2A 11.13 12.46 5.64 33.90 15.29 21.54 16.18
## PLAUR 5.11 5.08 4.83 2.32 4.21 3.89 5.47
## ANLN 60.32 78.71 45.19 29.27 50.85 53.45 61.01
## WIZ 19.46 23.66 17.27 19.73 19.77 20.23 20.42
## RABGAP1 10.30 13.37 10.21 21.00 14.31 14.98 16.41
## DCN 0.58 0.30 0.48 0.23 0.23 0.16 0.05
## QPCTL 11.31 12.12 11.21 9.70 12.13 13.02 13.25
## PPP5C 62.24 70.01 63.04 36.06 59.71 62.28 62.86
## CEP68 4.47 4.36 3.75 6.15 5.81 6.29 6.82
## MAP4K3 10.38 12.68 9.33 19.19 15.02 16.35 14.87
## ZBTB32 0.44 0.32 0.34 0.52 0.24 0.30 0.51
## TYROBP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMEM159 8.91 8.03 7.69 16.30 13.15 10.77 13.06
## GABRA3 1.26 1.87 1.48 0.68 1.20 1.03 1.68
## BRCA1 36.37 37.46 25.51 27.43 38.45 32.50 36.38
## ERCC1 34.24 35.43 34.40 25.82 30.11 35.17 34.97
## CD22 0.00 0.00 0.00 0.03 0.00 0.00 0.00
## MBTPS2 14.66 16.29 12.11 9.23 15.25 16.45 15.84
## PRICKLE3 9.01 10.54 7.95 9.40 11.51 10.87 12.05
## LTF 0.00 0.00 0.08 0.00 0.00 0.10 0.00
## EXTL3 13.05 15.12 11.47 18.05 14.48 15.78 14.78
## NR1H4 1.58 3.50 2.48 0.15 0.53 0.77 1.08
## ELOVL5 80.19 110.85 81.89 168.15 119.10 104.13 102.99
## ALOX5 0.02 0.07 0.04 0.00 0.19 0.01 0.00
## KDM5D 9.19 12.13 8.24 7.86 8.94 9.98 8.16
## CALCOCO1 22.06 30.62 26.38 16.53 26.06 26.39 33.80
## UBR7 43.73 45.49 34.94 41.95 42.95 41.92 44.88
## MAP4K5 11.66 15.50 10.43 24.76 17.29 14.94 16.34
## EHD3 0.71 0.62 0.39 0.09 0.14 0.42 0.29
## PSMC4 123.91 109.84 96.42 206.76 144.46 151.03 99.18
## MAN2B2 11.54 10.31 8.03 13.25 9.33 10.25 11.44
## SLC7A14 0.02 0.04 0.06 0.02 0.04 0.02 0.04
## CLDN11 32.81 58.18 46.57 15.44 32.70 28.83 38.20
## SLC25A39 365.03 377.98 384.12 272.26 356.03 374.16 321.58
## MVP 74.25 86.78 77.02 132.62 102.05 102.42 92.66
## NUB1 66.23 65.87 51.08 74.40 68.44 73.35 62.21
## PGM3 22.56 20.17 14.60 29.46 23.85 31.41 24.43
## RWDD2A 12.58 13.03 11.15 15.31 14.22 16.47 16.08
## CLK1 28.80 33.75 41.67 98.87 36.18 36.41 46.39
## POLR3B 12.70 12.12 9.11 4.91 11.06 14.30 10.07
## ANGEL1 6.90 7.74 5.30 8.49 7.34 7.20 7.81
## RNF14 44.19 44.58 34.03 83.65 65.61 63.29 52.80
## DNASE1L1 28.43 37.98 32.26 15.23 15.12 18.36 18.64
## DDX11 52.58 50.21 43.99 31.77 53.23 45.78 64.52
## HEBP1 37.62 35.27 36.15 25.88 38.48 38.22 39.42
## GPRC5A 4.07 1.94 1.60 2.12 3.31 2.88 2.03
## MAMLD1 1.25 1.11 0.88 0.86 0.98 0.90 1.18
## CD6 1.32 1.20 0.77 0.29 0.31 0.43 0.52
## TACC3 89.28 102.30 88.85 55.69 72.76 66.36 84.70
## UFL1 12.48 11.92 7.41 20.63 15.01 17.57 15.08
## POLA2 48.39 48.86 40.34 26.32 38.97 33.82 32.75
## ZC3H3 11.64 11.18 10.12 18.88 13.42 13.43 12.24
## CAPN1 49.32 52.27 44.11 45.23 56.61 54.45 54.44
## ACPP 8.02 8.68 6.12 1.60 4.66 4.14 6.23
## MDH1 316.66 304.51 281.02 294.42 337.48 367.76 289.39
## SLC30A9 63.17 67.39 49.70 54.53 67.27 74.69 69.36
## MTMR11 11.14 10.54 11.42 28.33 17.31 12.57 22.40
## COX15 52.37 49.06 35.97 51.82 60.93 69.23 51.96
## CCDC88C 2.84 3.18 2.50 0.81 2.43 2.77 2.52
## YAF2 13.50 16.02 9.89 24.65 15.08 16.66 15.39
## ZMYND11 30.42 38.51 28.15 38.93 38.72 38.16 37.08
## WAS 0.65 1.13 0.88 1.83 1.19 0.75 1.24
## DPEP1 0.10 0.00 0.03 0.00 0.00 0.02 0.02
## BID 8.38 8.35 8.43 8.05 8.53 9.52 7.47
## MATR3 234.16 236.71 187.00 158.96 222.85 243.16 186.55
## NPC1L1 0.43 0.86 0.53 0.47 0.24 0.31 0.64
## XYLT2 6.40 5.79 5.87 5.39 5.95 5.86 6.94
## RGPD5 1.19 1.97 2.29 8.14 3.12 5.81 3.67
## STMN4 3.07 1.45 1.72 1.07 1.52 1.75 0.71
## NUDCD3 47.05 46.92 42.57 66.83 48.97 49.61 50.94
## ISL1 1.17 0.69 0.77 1.66 1.20 1.52 1.06
## CHDH 9.33 10.99 7.26 5.31 7.69 9.47 9.55
## IL20RA 0.58 0.34 0.21 0.06 0.06 0.10 0.11
## CLCA1 0.00 0.00 0.01 0.00 0.00 0.00 0.02
## CLCA4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GLT8D1 54.73 67.59 67.49 36.94 48.14 51.26 53.80
## ATP2C1 58.09 62.53 49.94 77.36 72.86 77.96 70.14
## SRCIN1 6.44 5.69 5.33 3.73 3.90 4.56 6.44
## IGF1 0.44 1.84 1.14 0.46 0.40 0.37 0.49
## SLC38A5 0.32 0.62 0.81 0.45 0.52 0.20 0.38
## MAGIX 0.79 0.52 0.70 1.62 1.13 1.26 0.87
## RALBP1 24.17 27.53 20.38 35.78 30.12 30.91 26.50
## RUFY3 10.27 10.58 6.52 10.25 12.60 13.63 11.17
## CNTN1 1.80 2.66 1.15 0.38 0.68 1.30 2.05
## SLC11A1 1.74 1.07 1.05 1.25 0.99 1.56 1.43
## WWTR1 4.80 4.03 2.73 3.84 2.55 2.40 3.44
## AGPS 3.35 3.54 2.30 2.52 4.10 4.63 3.40
## CXorf56 18.03 17.87 16.62 27.98 21.75 22.87 20.54
## ATP1A2 0.00 0.01 0.00 0.00 0.01 0.00 0.01
## TTC27 15.22 16.16 14.27 6.34 13.57 15.13 13.95
## ZNF582 2.92 2.91 3.20 2.68 2.94 3.57 3.74
## VSIG2 0.30 0.16 0.28 0.27 0.34 0.12 0.22
## PHLDB1 7.97 8.05 7.06 6.05 7.16 8.22 8.11
## MARCO 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CYP24A1 0.00 0.00 0.02 0.00 0.05 0.00 0.05
## PRDM11 0.74 0.80 0.55 0.55 0.58 0.43 0.58
## SYT13 0.09 0.02 0.00 0.00 0.01 0.02 0.00
## SNAI2 0.02 0.01 0.01 0.03 0.00 0.02 0.01
## CD74 0.00 0.16 0.04 0.03 0.07 0.00 0.02
## HGF 154.71 166.18 138.77 30.02 98.93 125.87 109.51
## ZRANB1 8.11 10.63 7.32 15.17 9.40 9.74 10.58
## NCDN 32.87 29.37 22.06 24.58 32.78 41.87 27.80
## GPR124 0.01 0.01 0.06 0.01 0.00 0.02 0.00
## ZFP64 8.96 9.21 7.26 8.58 8.96 9.97 9.70
## MNAT1 45.74 45.97 45.68 43.67 41.47 49.78 43.14
## SAMD4A 4.12 5.03 2.52 2.55 2.17 2.44 2.24
## RUNX3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MRE11A 5.15 4.51 3.51 8.18 5.84 5.55 6.49
## PLEKHB1 3.62 4.11 2.92 2.14 2.12 2.00 2.72
## SERPINB1 57.22 55.54 54.26 25.36 35.83 43.92 39.80
## CYP3A43 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SLC7A9 0.24 0.22 0.38 0.27 0.28 0.24 0.32
## SPAST 6.72 7.45 5.46 12.71 10.10 9.32 8.55
## NRXN3 0.04 0.02 0.01 0.00 0.03 0.01 0.01
## OSBPL5 21.39 14.39 12.54 19.77 18.10 24.20 18.71
## AQR 19.19 17.36 16.24 22.94 20.33 19.72 18.32
## CPS1 0.63 0.68 0.31 0.18 0.13 0.29 0.45
## C8B 0.00 0.00 0.00 0.02 0.00 0.00 0.00
## FHL1 0.10 0.18 0.02 0.01 0.00 0.03 0.05
## RTFDC1 74.34 70.34 62.68 62.00 69.00 73.67 66.00
## GABRA1 6.52 6.41 5.07 3.01 4.56 6.74 5.30
## NLRP2 0.14 0.00 0.03 0.02 0.00 0.00 0.00
## SLC45A4 3.46 3.31 2.41 8.68 3.78 4.78 4.32
## RNF10 128.70 123.81 110.35 154.60 140.53 127.85 125.43
## ZNF839 17.78 15.55 18.52 18.14 15.78 16.23 18.93
## ZDHHC6 17.46 15.03 15.61 17.81 17.22 15.55 16.90
## GRAMD1B 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## RNH1 87.59 86.79 81.63 98.48 98.37 98.74 85.91
## NDUFS1 91.72 101.50 68.08 84.94 93.83 116.90 92.36
## RB1CC1 9.28 12.81 8.82 48.58 17.11 17.21 16.35
## ERP44 28.43 27.14 21.13 33.12 35.02 34.78 34.75
## ALAS1 40.70 40.62 36.78 50.23 46.63 50.32 30.74
## BIRC3 0.68 0.58 0.50 0.40 0.45 0.75 0.51
## AKAP11 6.43 6.62 4.38 7.54 6.81 8.25 7.17
## GLRX2 40.38 37.48 35.98 64.71 50.96 49.80 37.05
## SNAPC1 6.32 6.94 5.99 5.63 6.93 6.46 7.89
## DERA 48.89 49.51 37.89 41.25 45.01 47.55 43.78
## STRAP 245.88 227.41 189.07 402.95 288.04 315.79 215.52
## ABCC2 3.30 3.68 3.00 7.26 6.11 6.30 4.47
## DEF6 12.19 9.59 9.64 10.09 11.06 12.96 12.91
## PLEKHO1 8.55 11.24 12.32 9.86 5.53 6.73 6.26
## GCLM 29.66 17.94 13.98 118.73 81.38 79.22 50.64
## UBR2 8.40 9.61 6.77 11.48 9.44 10.76 10.15
## EHD2 1.00 0.86 0.64 1.07 0.83 0.85 0.75
## DEPDC1 16.59 20.72 13.71 8.99 12.31 12.01 15.83
## CCDC28A 13.39 14.93 13.83 28.02 18.71 16.62 19.62
## RRAGD 23.10 19.87 18.05 52.67 38.52 38.31 42.74
## HSF2 10.57 13.11 11.10 14.99 13.01 12.41 12.51
## PHF20 13.61 13.62 10.30 15.76 14.57 16.18 15.99
## HSD17B6 1.83 3.36 2.42 0.99 1.92 1.82 1.34
## NR1H3 20.66 18.20 16.91 11.43 18.07 21.80 13.52
## TYMP 17.91 15.56 17.27 4.67 8.75 10.05 9.83
## NCAPH2 51.21 53.42 48.73 49.04 45.46 40.00 44.52
## TOMM34 44.58 45.62 38.03 51.41 51.57 58.99 47.42
## SEC63 35.48 33.83 32.16 39.55 33.36 33.50 31.29
## KPNA6 19.17 20.27 15.07 28.96 22.66 22.85 20.67
## VIM 13.42 9.81 10.89 4.31 6.27 7.81 10.28
## RTEL1-TNFRSF6B 1.43 1.93 2.08 1.24 1.31 1.54 2.38
## FAS 4.30 4.47 3.36 10.38 8.36 10.36 6.09
## RNASET2 41.50 30.76 35.92 21.23 34.50 37.45 40.88
## CD44 64.61 58.84 56.15 43.10 48.18 62.78 50.31
## KCNG1 0.31 0.89 0.72 0.05 0.25 0.29 0.34
## AGPAT4 0.20 0.27 0.32 0.30 0.03 0.19 0.07
## SLAMF7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## BTN3A1 1.34 1.42 0.90 0.45 0.33 0.48 0.75
## MIPEP 36.07 35.20 32.37 12.90 23.61 25.99 27.12
## PRKCH 1.39 1.25 1.46 0.45 1.02 0.71 0.64
## INSRR 0.11 0.10 0.10 0.03 0.02 0.06 0.13
## IFNGR1 14.84 14.90 12.15 31.07 18.94 19.31 18.32
## B4GALT7 13.76 12.24 13.10 15.25 14.67 16.05 13.71
## SH2D2A 1.91 1.63 1.17 0.10 0.62 0.93 0.51
## VRK2 27.44 23.59 18.61 35.33 30.24 34.48 28.60
## TNFRSF1B 0.05 0.06 0.02 0.01 0.02 0.03 0.02
## VEZT 64.97 69.03 51.42 74.98 71.75 82.34 62.88
## POU2F2 0.06 0.13 0.12 0.13 0.05 0.14 0.13
## BRD9 25.57 25.09 21.69 46.13 32.85 32.52 29.63
## SNX1 58.85 67.52 55.82 60.09 55.91 61.73 55.49
## TBPL1 25.35 27.42 22.87 31.67 24.45 25.25 27.06
## ARNTL2 4.53 3.94 2.87 2.03 3.92 2.85 2.92
## BCLAF1 87.55 87.75 51.45 104.27 75.47 98.55 64.93
## SLC39A9 49.09 50.74 39.49 94.15 55.83 61.08 56.23
## ANK1 0.91 0.91 0.96 0.80 1.01 0.81 1.11
## IBSP 0.00 0.18 0.09 0.03 0.00 0.07 0.00
## TFB1M 11.12 10.02 9.74 8.04 11.37 12.95 10.54
## RABEP1 31.33 31.58 22.80 30.00 32.21 34.59 27.05
## HMGB3 103.44 102.59 88.99 74.00 82.84 90.84 79.97
## NUP160 22.41 27.81 19.31 25.56 25.78 27.85 25.13
## BAK1 15.71 12.12 11.49 41.35 22.31 21.47 15.49
## MUSK 0.00 0.00 0.02 0.00 0.00 0.00 0.00
## IKZF2 0.82 0.48 0.41 0.78 0.92 0.90 1.05
## GRN 89.62 83.42 84.41 135.37 101.55 103.35 115.41
## FAM13B 9.57 10.37 7.77 16.46 12.97 12.08 10.61
## ARHGAP31 0.92 0.68 0.52 1.73 0.81 1.17 0.73
## CENPQ 16.46 18.29 14.32 17.70 17.44 15.79 15.52
## SARS 132.86 110.61 104.94 219.57 193.77 178.05 173.65
## RANBP3 31.10 40.12 32.51 45.42 35.13 37.53 38.96
## ARID4A 6.88 5.92 4.40 14.10 7.54 8.19 8.53
## TSSC1 28.92 32.34 30.16 25.72 27.25 29.51 25.38
## PNPLA6 32.56 36.99 31.59 44.96 50.18 45.16 47.76
## IFT88 15.34 13.63 12.78 15.67 16.31 16.90 14.08
## ALG1 29.86 29.82 28.47 18.13 25.80 29.86 23.23
## ZCCHC8 23.26 20.48 19.07 36.77 30.68 27.11 27.22
## ABCF2 60.66 58.63 40.49 76.37 58.69 66.88 44.25
## CHPF2 16.01 17.69 18.97 75.50 24.23 22.58 20.80
## LRRC7 0.40 0.41 0.37 0.35 0.33 0.48 0.58
## FUT8 7.82 6.29 4.24 5.85 7.78 7.69 8.55
## UBA6 16.41 15.86 11.20 27.65 21.49 26.91 20.83
## GAB2 3.50 5.04 3.54 5.86 4.54 5.08 4.97
## ATP6V0A1 40.52 36.82 35.74 54.87 56.53 54.43 49.85
## PIAS1 7.83 8.89 5.37 11.83 8.86 8.86 8.37
## SLC4A7 2.61 2.86 1.55 4.40 3.53 4.82 3.00
## APBA2 10.31 10.45 8.80 5.29 9.71 10.50 10.65
## MAP2K3 61.76 48.93 49.58 191.58 88.01 86.40 61.99
## EFCAB1 0.00 0.00 0.05 0.06 0.06 0.00 0.00
## TMSB10 8667.99 9634.93 9738.34 3841.11 6594.14 7287.26 7926.99
## ASTE1 4.81 4.86 3.62 5.45 4.58 5.15 4.72
## RNF19A 7.45 6.03 4.28 15.08 10.37 8.81 9.71
## PEX3 28.45 27.52 23.61 34.08 36.58 39.33 34.16
## GABARAPL2 138.68 159.08 160.18 224.79 169.33 171.63 165.62
## MYOC 0.00 0.00 0.00 0.02 0.00 0.00 0.00
## SH3YL1 14.98 18.59 14.04 17.63 13.74 15.35 12.14
## FAM136A 89.05 91.88 80.73 48.87 75.74 83.61 69.02
## VCL 28.28 24.42 17.73 27.70 28.93 29.09 28.12
## DEPDC1B 18.33 23.74 16.76 7.22 12.28 12.12 13.97
## DAPK2 1.57 1.36 2.10 2.56 2.01 2.10 1.33
## NSMAF 13.35 17.10 12.75 11.76 12.78 15.14 13.95
## ADSS 30.86 31.70 26.83 33.57 34.75 37.63 32.60
## STAP1 0.00 0.00 0.00 0.02 0.00 0.00 0.02
## TIMP2 0.45 0.62 0.43 0.46 0.23 0.26 0.44
## RFC1 44.12 47.39 36.65 53.81 45.01 46.53 50.53
## TBC1D23 4.74 4.39 3.72 12.23 7.20 7.47 6.24
## CUL3 76.82 79.94 71.21 111.32 79.70 82.36 73.58
## MYOM2 0.41 0.17 0.42 0.41 0.88 0.31 0.55
## OTC 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CYP46A1 0.16 0.10 0.07 0.18 0.32 0.32 0.39
## ZZZ3 26.02 26.42 18.26 28.47 28.32 30.41 29.56
## SLC18A1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## USP2 1.50 1.36 1.20 1.38 1.32 1.67 1.64
## CASR 0.01 0.00 0.00 0.00 0.00 0.00 0.00
## TUBG2 12.99 13.25 13.77 10.90 12.49 11.86 11.74
## RPL26L1 104.70 90.83 92.96 91.18 94.21 109.75 76.54
## FLT4 0.68 0.48 0.32 0.20 0.46 0.64 0.38
## NSUN2 55.05 67.27 58.81 68.49 55.63 58.51 51.87
## FBXO42 12.10 13.43 12.13 28.55 19.14 17.08 21.11
## MFAP3 17.05 19.23 14.13 33.03 22.28 26.34 20.67
## MRI1 22.55 22.20 17.85 8.85 15.99 18.59 18.25
## METTL1 87.03 78.73 78.42 28.36 65.86 82.70 53.87
## HOXC8 0.70 0.61 0.91 0.41 0.60 0.82 0.56
## AGA 9.36 6.69 5.99 3.94 4.91 7.13 7.52
## PI4K2B 22.25 25.93 19.34 24.63 24.01 27.15 22.30
## BOD1L1 7.39 7.50 6.33 11.82 7.64 9.25 9.22
## MAT2B 49.22 63.22 48.24 61.79 54.60 58.70 54.00
## TLL1 0.85 0.51 0.31 0.14 0.28 0.65 0.42
## EDC4 40.77 47.44 47.47 56.14 46.77 43.04 47.23
## TRIO 6.53 6.70 5.79 10.92 6.76 7.83 8.62
## VCAN 2.23 1.67 1.54 3.24 1.59 1.84 1.64
## CLEC16A 10.94 10.82 7.97 11.65 12.23 14.20 12.36
## MSR1 0.15 0.41 0.24 0.09 0.08 0.03 0.04
## CDH1 178.32 183.51 186.81 219.09 200.40 203.14 208.95
## SKIV2L2 33.88 33.85 24.41 28.30 35.13 40.07 31.55
## DNAH5 0.61 0.75 0.80 0.09 0.31 0.20 0.38
## ZFYVE16 10.74 9.73 7.38 18.04 11.89 15.45 14.60
## FAM65A 23.84 29.92 25.67 16.20 21.17 20.61 30.40
## C6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RAI14 10.53 11.79 8.16 10.10 15.00 16.53 10.91
## SOX30 0.03 0.03 0.02 0.00 0.00 0.00 0.01
## PNKP 20.07 32.87 33.00 24.47 19.19 20.20 26.51
## BEST2 0.04 0.13 0.13 0.35 0.05 0.06 0.14
## PHLPP2 4.89 4.42 3.32 9.97 6.33 6.04 5.58
## SPDL1 22.01 25.43 18.05 16.38 16.50 17.89 18.14
## STAU2 21.08 20.38 13.88 19.72 20.67 25.27 25.71
## PQLC2 12.29 13.06 11.94 23.34 14.35 13.67 11.47
## CTNS 6.71 7.24 6.18 9.69 7.14 7.10 6.69
## RTN4R 4.27 4.08 4.26 9.41 5.57 4.27 4.97
## PHF23 43.79 42.64 41.97 50.47 47.26 51.93 39.68
## CDH10 0.16 0.28 0.43 0.00 0.06 0.11 0.06
## INPP4A 3.24 3.95 2.50 3.23 4.24 4.16 4.64
## RAB27B 6.11 5.67 3.92 1.31 2.87 4.77 3.80
## PSMA4 296.17 275.07 259.94 252.13 287.17 315.82 236.38
## MYO16 0.00 0.00 0.00 0.00 0.00 0.02 0.00
## LSG1 24.02 23.92 19.93 42.42 30.20 31.17 24.39
## PARP3 5.86 4.44 4.42 5.59 4.86 5.58 6.78
## TNC 6.36 10.31 7.83 1.86 3.55 4.70 5.42
## THAP3 17.76 17.75 18.49 24.93 18.94 18.05 18.20
## FAM65C 0.00 0.01 0.09 0.15 0.00 0.00 0.01
## TDP1 16.94 17.17 12.63 12.27 17.61 16.47 17.07
## AIFM2 1.45 1.19 1.43 2.98 2.12 2.16 1.59
## C2orf83 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SPATA7 3.50 3.04 2.81 3.18 2.99 3.47 3.23
## MED17 29.63 33.91 29.27 55.03 35.23 39.36 30.34
## RETSAT 14.81 9.76 10.11 31.78 15.24 12.97 13.40
## CAPG 5.77 3.88 5.04 6.02 5.10 5.08 5.65
## AP2S1 293.44 271.45 284.54 227.51 303.97 299.60 256.23
## USH2A 0.01 0.02 0.01 0.00 0.00 0.01 0.01
## ZPBP 0.04 0.00 0.08 0.00 0.00 0.09 0.00
## TG 0.00 0.00 0.00 0.22 0.00 0.10 0.08
## ADAM28 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## BARX2 0.00 0.00 0.02 0.00 0.00 0.06 0.00
## DCUN1D1 17.02 18.30 12.00 29.40 21.96 25.18 20.84
## JADE2 13.90 15.74 9.73 11.34 12.62 13.48 13.93
## ZIC2 4.08 4.77 5.24 4.36 4.34 4.38 4.85
## LCP2 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## TRIT1 21.49 23.64 20.92 13.68 16.41 19.01 18.85
## ADRB1 0.18 0.08 0.09 0.17 0.18 0.09 0.25
## GUCA2B 0.16 0.18 0.00 0.00 0.00 0.07 0.18
## CUL7 10.63 10.50 9.42 13.59 13.08 12.72 14.65
## CTNNA1 176.10 188.84 153.86 273.66 202.77 206.22 190.12
## PHKA2 4.28 4.55 4.31 2.91 3.93 4.42 5.42
## CNTLN 4.65 5.49 3.10 2.62 3.96 4.59 4.36
## EPHA3 26.93 44.12 28.78 8.80 27.51 36.63 36.49
## HSPA5 252.75 294.71 211.17 137.09 191.28 235.69 185.33
## DSG2 32.88 27.71 20.07 57.27 39.43 41.16 40.12
## GEMIN8 16.78 20.24 19.43 12.51 14.65 15.49 14.83
## OFD1 13.76 15.83 17.65 26.49 18.39 12.79 14.23
## GPM6B 2.61 2.94 2.24 0.74 2.02 2.78 2.49
## MAGEC2 0.45 0.18 0.21 0.08 0.21 0.34 0.18
## PREX2 0.13 0.11 0.15 0.04 0.12 0.12 0.30
## WDR37 9.77 8.85 6.79 25.09 11.46 12.65 11.91
## YTHDC2 10.17 12.46 9.49 6.94 9.19 11.87 10.61
## CTPS2 9.95 8.23 6.29 4.42 8.25 7.76 9.04
## ATP6V1H 49.82 44.50 37.20 91.57 67.07 72.50 55.62
## POLR2B 67.25 83.21 58.19 106.97 83.28 93.00 79.77
## FAM214A 9.52 8.01 8.76 48.55 17.63 16.34 13.11
## ARAP2 2.04 2.00 1.49 4.16 2.96 3.25 2.35
## TPR 61.83 72.68 64.10 71.08 62.84 66.64 70.60
## CP 2.13 2.06 3.20 1.36 2.41 3.37 3.09
## KIAA0556 8.54 8.32 6.23 10.67 9.91 9.77 10.96
## DTNBP1 19.76 21.17 20.45 15.33 18.70 19.21 18.85
## XK 1.47 1.72 1.06 0.29 0.74 0.91 0.82
## ANO2 0.23 0.24 0.30 0.06 0.15 0.07 0.08
## C12orf4 18.96 16.86 11.63 20.45 22.86 21.84 19.67
## SCML1 18.93 16.77 14.63 36.23 25.25 26.01 25.55
## WWC3 3.19 2.38 1.81 4.57 3.26 3.00 2.67
## ARHGAP6 16.11 25.52 17.87 3.58 13.17 15.85 18.17
## FAM184B 0.93 1.39 1.02 1.60 1.22 1.33 1.09
## MAP4 123.33 117.53 94.31 115.04 142.32 147.31 158.31
## GOPC 14.38 16.41 12.81 26.21 18.57 19.21 18.08
## ROS1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## USP28 5.30 5.72 4.48 3.11 4.56 6.04 7.41
## HDAC9 1.42 0.47 0.36 0.27 0.60 0.65 0.63
## TSPAN17 34.07 35.51 28.67 54.69 40.82 40.30 35.41
## NOP16 89.46 98.85 99.99 55.71 83.95 93.82 65.59
## CC2D2A 3.92 2.46 1.89 0.40 1.03 1.77 2.09
## RRM2B 17.24 15.73 11.50 44.75 27.20 31.03 23.87
## ZNF800 18.08 15.17 12.23 41.71 20.80 22.00 20.55
## TNFRSF17 0.00 0.00 0.00 0.18 0.00 0.00 0.00
## SNX29 2.84 2.73 1.68 1.16 1.56 2.59 2.15
## LMO3 0.42 0.31 0.26 0.18 0.09 0.36 0.18
## MRPS10 51.98 46.83 38.85 51.08 49.01 53.01 44.48
## GUCA1A 0.00 0.02 0.00 0.02 0.00 0.00 0.00
## RSF1 7.17 5.99 4.08 10.21 8.40 9.64 10.33
## VPS13D 10.92 11.26 10.45 11.27 12.29 13.92 13.02
## CELF2 0.02 0.00 0.00 0.00 0.00 0.00 0.00
## FAM120A 64.63 77.40 55.71 79.22 81.66 83.60 76.55
## R3HDM1 10.80 11.91 7.05 10.76 12.01 11.90 12.55
## COL9A2 1.86 2.76 2.58 1.21 1.58 1.33 1.67
## KITLG 4.09 2.29 1.66 2.82 2.98 3.95 3.14
## ERCC8 8.79 8.27 6.75 6.97 8.44 9.95 7.97
## ADAMTS6 0.16 0.09 0.04 0.09 0.10 0.05 0.24
## H6PD 5.85 6.34 4.97 3.88 4.55 5.08 6.37
## VAMP3 43.34 38.96 36.57 85.64 54.25 54.77 43.47
## PER3 0.44 0.30 0.20 0.40 0.16 0.46 0.26
## UTS2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TNFRSF9 0.02 0.00 0.00 0.00 0.00 0.00 0.00
## EPN3 14.87 20.61 17.71 2.74 7.42 11.36 8.70
## LTBP1 1.86 1.92 1.45 0.88 1.03 1.20 1.75
## RCN1 44.19 51.33 46.53 25.71 36.86 33.74 41.47
## ELN 0.04 0.12 0.06 0.03 0.00 0.07 0.03
## RFC2 160.23 170.41 146.78 72.31 112.12 118.58 114.42
## ARID1B 7.95 9.35 5.25 11.15 8.38 9.41 10.08
## CLPTM1L 81.41 95.17 96.33 103.75 96.28 90.99 76.87
## NEDD4L 27.48 27.94 23.12 34.99 28.41 33.43 26.80
## FOXP3 0.28 0.21 0.24 0.22 0.28 0.20 0.52
## PPP1R3F 1.64 6.67 6.42 6.59 2.91 2.41 3.32
## HEXB 125.93 102.07 98.13 206.67 118.67 134.27 115.50
## PTCD2 10.01 8.89 6.06 11.70 12.47 12.44 11.42
## KIAA2022 0.11 0.14 0.10 0.07 0.09 0.12 0.20
## JKAMP 51.25 53.77 42.82 82.00 69.69 75.39 56.06
## DKK3 0.13 0.00 0.08 0.04 0.00 0.04 0.02
## ARHGEF5 15.05 13.43 11.89 43.87 20.63 19.66 20.29
## NFE2L3 2.98 4.74 3.69 3.66 1.95 2.27 2.79
## MCUR1 23.43 21.34 15.98 23.08 24.78 27.73 23.96
## LIMA1 36.26 40.89 33.37 49.43 39.01 41.44 37.88
## LETMD1 105.51 108.43 119.09 96.25 105.74 113.21 143.61
## SLC4A8 1.66 2.50 1.73 0.64 1.04 2.00 2.23
## LAMC3 0.13 0.28 0.27 0.04 0.05 0.05 0.05
## PTGER3 0.45 0.64 0.63 0.30 0.13 0.24 0.30
## TNIP3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MAPK9 30.94 35.69 24.83 41.52 33.49 34.52 31.90
## COL23A1 0.05 0.04 0.04 0.00 0.00 0.02 0.01
## BCAR1 23.67 24.04 18.98 54.84 28.09 28.93 22.22
## FAM160A2 18.35 14.98 15.90 40.68 22.12 21.99 22.29
## HERPUD1 51.78 63.79 52.31 114.47 84.58 83.48 93.14
## HOMER3 14.68 17.01 15.48 9.39 9.64 11.15 12.59
## RAD51 51.54 45.43 40.65 24.50 42.67 36.12 35.83
## POLQ 4.09 4.52 2.95 3.95 4.03 4.62 4.16
## PIK3CB 22.89 24.33 18.95 24.38 27.49 27.04 25.46
## CYBA 0.65 0.27 0.49 2.77 0.31 0.89 0.59
## THOC3 92.83 100.75 89.07 67.85 92.19 91.89 96.26
## HEBP2 281.41 341.54 343.43 192.87 260.24 310.60 245.12
## MPHOSPH9 27.56 30.90 28.18 23.67 31.80 31.27 32.61
## PLEKHA5 10.79 12.33 10.49 8.66 10.35 11.20 12.01
## PRSS8 11.57 11.85 12.02 10.61 13.55 12.23 18.60
## SIKE1 23.70 19.15 13.46 30.45 26.05 27.53 22.10
## RRP12 52.63 41.46 45.14 52.03 55.39 57.64 40.90
## FNIP2 2.59 3.03 1.85 11.55 5.53 5.50 4.63
## MSMO1 67.39 81.17 58.66 142.78 104.51 110.92 118.55
## TTC17 24.92 29.02 24.62 43.56 33.44 32.76 37.72
## ALX4 0.97 0.76 0.66 0.33 0.70 1.04 0.88
## FSTL4 0.81 0.91 0.63 0.34 0.12 0.28 0.47
## FOXN3 2.39 3.43 2.62 2.61 2.50 3.60 4.64
## METTL24 0.24 0.11 0.13 0.06 0.08 0.06 0.08
## AKR7A2 55.21 57.86 57.35 34.96 49.64 52.05 49.22
## MRTO4 60.27 61.09 57.44 30.32 48.10 54.97 41.09
## NNAT 0.13 0.12 0.32 1.66 0.44 0.48 0.34
## USE1 35.37 38.47 39.04 18.32 28.17 38.22 30.93
## MCF2L2 0.09 0.06 0.00 0.05 0.10 0.09 0.26
## NRIP2 1.15 1.21 0.89 1.13 1.17 1.46 1.75
## LAMA3 1.44 1.28 1.78 0.92 0.82 1.27 0.87
## AP5M1 22.16 25.97 19.44 32.49 25.56 31.56 23.45
## ANAPC4 17.35 14.59 13.61 16.79 14.53 15.78 13.91
## KCNQ1 0.56 0.82 0.62 0.25 0.25 0.37 0.49
## TRAPPC3 80.58 92.32 75.15 133.01 94.87 97.78 92.98
## THRAP3 70.72 81.11 59.35 92.46 79.56 91.55 88.69
## PHPT1 171.40 147.15 176.96 63.86 130.09 143.63 162.24
## ENTPD2 13.48 11.41 12.79 5.82 8.28 10.18 13.35
## LY75 0.00 0.00 0.00 0.02 0.00 0.00 0.00
## ARID4B 18.66 20.76 14.88 33.58 22.87 25.99 22.75
## OPN3 1.66 1.82 2.06 4.30 2.03 1.64 1.88
## SDCCAG8 43.57 46.02 40.65 42.45 47.75 49.40 47.50
## PTPRN 0.21 0.16 0.03 0.20 0.16 0.47 0.31
## HHAT 1.65 1.83 1.12 0.44 0.61 1.12 1.56
## KIF1B 10.24 10.05 7.01 19.45 15.38 14.85 13.03
## FOXC1 0.36 0.20 0.18 0.43 0.32 0.44 0.26
## TBC1D22A 14.84 12.54 11.09 10.98 13.32 16.09 14.01
## SYNE2 7.46 6.98 7.85 6.14 6.53 5.75 7.99
## PLEKHH1 6.81 9.59 9.92 6.73 6.77 7.88 11.47
## ATP9A 10.16 10.49 7.34 15.14 13.37 14.10 13.14
## SPO11 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CBLN4 0.36 0.48 0.46 0.16 0.49 0.44 0.33
## CHRDL2 0.00 0.00 0.00 0.02 0.05 0.03 0.00
## FAM168A 9.24 10.11 7.19 9.01 10.03 9.70 12.69
## RELT 4.29 4.07 3.42 15.96 7.03 5.95 6.86
## GALC 2.90 3.53 2.92 1.07 1.36 1.90 2.27
## NOP58 134.59 124.68 122.00 122.08 118.09 138.07 102.93
## SZRD1 93.18 105.91 83.43 160.08 109.19 114.32 93.17
## KCNH2 11.03 12.63 9.51 6.74 11.42 12.75 11.67
## CUL1 43.67 52.53 39.80 60.96 51.56 54.23 47.15
## FAM114A2 18.14 18.33 13.30 36.35 29.86 31.43 24.98
## CYFIP2 15.40 13.96 13.53 4.14 10.84 13.45 15.07
## TAB2 10.42 13.22 9.26 20.69 12.41 13.46 12.56
## GINM1 38.02 38.56 32.54 44.90 45.67 47.64 43.55
## EIF2AK2 12.22 11.75 7.70 10.33 11.39 14.57 12.60
## USP36 22.39 23.74 20.65 58.49 31.58 32.16 31.35
## KMT2C 11.50 13.65 12.37 20.73 13.45 16.74 15.80
## MCOLN3 0.15 0.10 0.13 0.06 0.08 0.10 0.14
## CCDC85A 1.45 3.11 2.35 1.76 1.87 1.29 2.19
## PUM2 36.69 43.61 33.03 47.91 46.97 47.91 50.19
## MRPL43 110.38 114.88 109.17 78.14 106.58 114.59 93.39
## ITIH4 2.05 0.97 0.97 1.14 1.06 1.85 1.45
## ITIH1 0.00 0.00 0.00 0.04 0.00 0.00 0.00
## C4orf27 19.55 16.16 16.06 15.22 18.93 18.88 16.68
## ZFR 21.43 22.51 17.77 41.92 33.21 36.69 31.05
## ZNF280C 2.60 2.29 1.83 3.02 3.20 3.52 3.12
## NPFFR2 0.00 0.00 0.00 0.21 0.00 0.00 0.00
## PHF21B 1.25 2.30 1.85 0.48 0.61 0.47 0.61
## TRAF1 0.69 0.62 0.64 0.59 0.51 0.38 0.83
## RC3H2 28.58 24.99 15.99 42.46 44.67 37.72 18.46
## PCGF2 25.58 27.40 27.28 19.76 25.41 25.59 24.81
## IL17RB 21.02 19.93 15.76 12.99 20.12 18.06 19.55
## TRAF3IP2 11.25 9.93 9.98 13.59 9.79 9.49 9.04
## GYG2 0.25 0.19 0.13 0.01 0.07 0.06 0.06
## DCBLD2 5.40 5.78 3.71 6.00 6.05 5.69 6.13
## SERPINB3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SOAT1 29.36 29.63 19.29 36.83 43.63 50.40 51.74
## PKP2 7.27 8.50 5.41 10.88 10.76 9.77 9.20
## MSH4 0.07 0.04 0.04 0.31 0.06 0.06 0.09
## F7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GDI2 176.07 170.68 135.06 177.11 172.85 188.74 158.35
## PRDM1 0.18 0.21 0.05 0.65 0.09 0.16 0.12
## ATG5 18.94 21.35 16.89 25.12 19.42 21.38 18.28
## TMCC3 1.22 1.85 1.24 0.32 0.59 1.35 1.38
## PITHD1 61.98 61.24 61.30 156.05 69.62 71.31 59.79
## MTA3 13.86 12.46 10.93 7.36 10.17 13.60 12.15
## USP13 8.43 9.90 6.74 7.09 9.12 10.04 9.54
## ATP11B 7.71 5.60 4.19 10.53 8.43 9.28 7.89
## LAMC2 2.26 0.53 0.92 4.96 2.78 3.09 1.32
## CDK14 23.12 24.84 18.13 17.97 25.67 30.81 27.39
## SEC61A1 108.31 107.25 95.03 177.51 122.00 124.51 117.20
## PPP1R12A 18.48 18.64 11.44 42.20 27.45 25.85 28.33
## RASGRF1 0.04 0.06 0.02 0.31 0.00 0.01 0.02
## CAMK2B 6.46 7.12 6.21 2.39 5.18 5.11 6.85
## CROCC 9.06 8.84 7.81 8.58 8.63 8.23 12.31
## POLR3E 31.97 34.94 32.59 23.42 30.08 31.97 23.32
## ATP2B4 3.63 3.36 2.46 1.07 2.08 2.79 3.00
## ZC3H11A 52.67 60.00 48.03 74.68 56.84 56.67 54.56
## RIOK2 34.25 24.91 22.60 64.30 31.19 32.89 27.32
## YIPF1 33.60 25.76 24.73 24.39 27.25 34.47 25.12
## NDC1 33.37 40.09 28.71 12.73 29.34 32.23 28.92
## DGKG 0.27 0.30 0.12 0.00 0.23 0.06 0.11
## FLYWCH1 12.61 11.39 9.64 22.56 16.57 13.82 12.86
## UNKL 10.86 11.24 9.89 24.31 18.25 14.30 18.42
## TBXAS1 2.86 2.47 1.64 0.66 1.08 1.48 0.75
## PARP12 3.57 3.87 3.46 0.94 1.96 2.08 1.60
## ALDH18A1 58.12 68.58 50.26 38.42 58.99 63.98 56.30
## TARBP1 6.65 8.73 11.13 2.62 5.38 5.38 9.02
## PET112 19.31 22.95 21.35 11.52 15.94 17.85 18.02
## MXD1 5.81 5.64 5.59 35.51 9.95 11.13 9.98
## CDK17 10.34 12.89 8.46 18.84 13.90 14.22 13.54
## DNAJC25 18.41 20.88 18.32 28.87 23.84 22.98 18.61
## SLC2A3 0.00 0.01 0.00 0.00 0.00 0.00 0.03
## PSD 11.23 14.78 15.15 12.59 10.76 11.21 18.08
## CTDP1 8.71 9.88 9.42 17.29 10.35 12.39 9.97
## YBX3 404.12 378.41 341.03 333.59 370.08 405.13 302.94
## STYK1 17.38 13.59 11.48 24.67 24.74 19.35 19.17
## WNK1 31.82 33.11 23.22 43.09 31.82 38.32 38.78
## CCAR1 39.84 38.70 41.17 57.63 38.08 47.49 37.55
## OGFR 20.48 22.49 23.04 26.62 17.65 16.48 17.66
## GNA15 0.11 0.10 0.05 0.03 0.00 0.00 0.03
## CREB3L3 0.02 0.00 0.02 0.01 0.00 0.00 0.00
## PIGV 10.45 15.20 12.94 10.77 10.28 10.08 12.52
## PTPRU 9.67 8.75 7.29 7.58 10.80 11.75 14.13
## SNRNP40 73.01 73.09 59.96 86.55 75.96 73.21 67.66
## RIMBP2 0.06 0.00 0.00 0.00 0.00 0.00 0.00
## COL11A1 0.00 0.00 0.00 0.05 0.00 0.00 0.00
## QSER1 6.31 5.98 3.66 5.00 5.56 6.73 5.69
## MPC1 39.42 41.09 36.33 80.01 65.78 63.41 50.61
## ACAA1 64.76 56.46 54.45 111.28 75.31 79.38 63.81
## BCAT1 0.70 0.30 0.26 0.54 0.38 0.63 0.58
## HDAC7 17.81 20.62 23.07 19.70 17.10 15.26 18.66
## LZTS1 0.03 0.03 0.00 0.03 0.01 0.01 0.00
## PRDM6 0.55 1.04 0.28 0.51 0.76 0.83 0.67
## WNT8A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SPAG4 2.68 3.24 3.05 1.87 1.20 1.70 2.04
## NCKAP1 65.17 71.81 52.35 86.35 82.92 88.61 73.90
## MRPS35 155.96 169.73 146.00 131.20 162.50 183.04 151.21
## GUCY1B3 4.53 3.82 2.68 3.63 4.16 4.06 3.76
## SFSWAP 23.64 26.94 24.36 25.91 22.92 25.75 25.38
## TNK2 8.82 8.22 8.52 7.75 8.21 7.54 11.98
## MON2 12.31 15.72 11.52 16.20 13.97 18.14 16.03
## CDH3 18.80 26.20 22.33 16.52 17.77 17.45 19.89
## ARSF 0.00 0.00 0.00 0.02 0.00 0.00 0.00
## GPBP1 48.29 48.18 44.53 68.93 55.93 51.52 50.99
## DGAT2 8.87 14.74 11.58 5.25 8.62 8.09 9.49
## ZNF112 1.46 2.05 1.52 3.86 2.18 2.27 2.28
## CS 320.14 332.65 255.46 236.64 330.08 349.20 337.22
## LTK 0.05 0.03 0.07 0.18 0.02 0.06 0.03
## MRPS24 176.20 198.66 189.84 129.27 166.28 171.48 153.14
## ELMO2 13.31 14.52 14.53 27.72 22.13 20.45 19.65
## WAPAL 21.30 18.92 16.42 28.78 22.53 22.64 19.94
## VMP1 59.42 47.91 37.81 64.22 61.87 68.54 42.47
## APPBP2 10.33 8.45 6.18 19.96 9.58 12.34 10.41
## POLD1 60.67 71.70 69.62 20.78 46.44 44.56 51.53
## SEZ6 16.22 22.71 16.56 6.11 13.24 12.73 16.13
## EIF4B 372.01 527.24 425.38 371.45 385.77 424.83 530.74
## SLC6A16 2.99 1.93 2.86 1.10 1.73 2.03 3.17
## GLTSCR1 4.74 4.84 4.35 11.55 4.96 6.20 6.54
## SPHK2 8.84 10.93 9.36 15.69 14.50 14.22 12.43
## RPL18 2398.22 2554.98 2851.67 2470.61 2419.83 2351.91 2665.56
## CA11 199.31 164.18 179.85 108.28 178.44 199.95 214.17
## ISOC2 118.24 154.35 136.92 44.57 95.34 105.94 95.37
## U2AF2 142.90 153.15 122.11 100.97 135.45 152.46 139.90
## EPN1 45.49 58.71 50.24 55.64 51.47 45.65 56.05
## MED29 31.96 30.36 24.66 38.87 28.00 31.04 27.99
## AHRR 0.54 0.99 0.71 0.76 0.36 0.68 1.01
## GSC2 0.08 0.03 0.00 0.00 0.03 0.03 0.00
## ZNF275 4.94 5.82 4.44 8.61 4.63 4.86 5.55
## MTMR1 17.58 20.22 14.67 13.86 14.43 15.87 15.55
## GPC1 4.42 4.98 4.53 5.93 4.98 4.49 6.61
## ADCK1 6.65 6.87 6.34 3.28 5.07 6.46 5.49
## HAGH 56.83 82.89 68.91 47.17 63.61 60.86 57.14
## RNF4 40.99 41.37 33.46 56.19 39.52 40.25 41.23
## CASP8 4.15 3.41 2.49 4.03 2.33 2.69 2.20
## LIMCH1 40.12 47.66 31.65 32.04 46.78 59.66 48.58
## ASUN 31.88 33.64 26.25 36.75 41.05 39.32 35.77
## TM7SF3 69.10 70.61 50.60 55.10 75.31 87.04 71.56
## DLX3 0.54 1.51 1.08 1.06 0.88 1.02 0.54
## SPA17 37.12 38.74 37.06 10.61 22.16 29.78 25.72
## TSPAN32 0.02 0.23 0.20 0.02 0.10 0.07 0.06
## WISP2 0.06 0.02 0.02 0.07 0.00 0.07 0.11
## DMRT3 0.09 0.13 0.05 0.09 0.11 0.13 0.06
## ST3GAL6 1.15 0.90 0.96 2.15 1.31 0.88 1.40
## ATP2C2 0.84 0.44 0.40 0.52 0.41 0.32 0.86
## NGFR 2.45 0.26 0.24 10.37 4.27 4.15 2.99
## CDON 1.32 1.83 1.19 2.58 1.86 1.94 1.93
## TAF2 16.49 15.25 10.50 25.87 18.66 21.85 16.60
## HIPK2 8.41 8.49 5.71 11.34 9.13 9.90 9.33
## TNPO3 38.25 40.01 24.91 57.71 45.41 48.96 42.81
## MEF2BNB-MEF2B 1.53 1.99 1.90 5.34 3.19 2.71 3.31
## RFXANK 61.67 65.26 72.60 49.82 59.16 67.47 65.65
## TMEM161A 41.22 41.12 44.24 40.07 52.70 44.21 44.16
## LPAR2 4.12 4.50 6.21 12.61 4.70 3.79 5.84
## CTSA 63.66 53.49 51.18 72.33 69.19 72.68 56.22
## SUGP2 15.96 20.27 22.67 25.03 20.83 18.94 23.97
## SLC12A2 11.69 10.12 7.59 10.52 13.09 16.94 11.56
## SNX24 5.46 4.50 3.99 3.78 6.56 5.62 5.77
## EYA2 0.05 0.05 0.06 0.02 0.00 0.04 0.05
## CNN2 25.62 24.99 21.42 19.27 24.81 20.87 20.74
## ABCA7 27.82 27.69 28.61 21.60 29.35 27.95 30.58
## SNCAIP 0.42 0.58 0.41 0.07 0.22 0.17 0.27
## DDX20 12.71 13.68 11.29 15.92 12.46 13.71 12.06
## BTBD1 57.05 56.84 46.32 48.55 57.25 63.83 47.92
## FAR2 36.58 43.01 29.65 15.74 25.40 31.20 31.36
## BCAS1 0.68 1.02 1.01 0.20 0.45 0.44 0.51
## POU1F1 0.10 0.08 0.06 0.09 0.00 0.00 0.04
## CHI3L2 0.00 0.00 0.00 0.08 0.00 0.02 0.02
## SBNO2 25.81 37.38 32.49 19.08 21.68 27.08 27.76
## PMS1 14.16 14.71 11.54 9.66 13.37 14.80 12.63
## HMG20B 236.77 264.54 260.27 132.87 197.77 217.44 244.11
## CALCRL 0.18 0.18 0.12 0.11 0.15 0.29 0.11
## TAF11 48.61 47.16 45.72 72.77 50.16 48.20 42.73
## ANKS1A 8.73 9.96 8.01 13.46 10.54 10.68 10.99
## AP3D1 51.46 56.96 50.99 50.24 54.04 58.41 53.83
## ZNF76 30.18 41.91 33.78 38.14 34.87 32.68 35.54
## SLC9A3R2 58.19 69.21 66.99 20.42 41.58 47.89 43.34
## NTHL1 37.88 40.59 38.72 8.95 24.21 28.53 24.63
## UHRF1BP1 7.42 7.43 4.79 10.42 8.54 9.15 8.93
## GNAI3 58.88 49.28 41.45 77.00 61.07 65.92 52.78
## IPO5 100.16 113.22 80.90 64.19 94.39 105.13 98.84
## OAT 75.10 69.87 53.62 119.91 101.20 132.00 58.26
## WDR3 38.79 35.59 24.55 51.85 50.59 60.58 41.78
## PKN2 14.58 17.80 12.70 22.09 17.77 20.58 19.45
## WDR18 63.77 64.20 65.70 34.55 51.19 58.25 50.11
## TRAM2 3.17 3.34 2.55 3.39 2.78 3.30 3.20
## NTN1 0.08 0.09 0.06 0.04 0.04 0.03 0.14
## GLP2R 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MCM10 23.12 20.83 13.39 8.49 16.25 16.67 16.05
## DGKA 24.84 18.21 18.21 23.14 28.38 29.28 20.31
## ERBB3 66.95 71.18 58.05 52.87 63.19 68.78 66.95
## ROPN1 0.00 0.00 0.09 0.10 0.02 0.00 0.02
## ANKRD44 3.75 2.88 0.82 1.25 1.71 3.26 3.63
## KARS 170.05 142.81 125.86 158.94 159.55 175.17 139.36
## ADAT1 45.27 43.69 32.86 29.53 38.99 48.64 40.62
## PDIA5 21.17 22.24 18.71 10.10 19.73 20.28 17.75
## TBC1D22B 5.44 5.68 4.56 12.98 7.19 7.44 7.18
## NDUFB4 332.11 312.25 324.07 283.32 375.46 403.31 331.26
## SPEN 26.80 28.21 23.70 23.37 22.13 26.23 27.55
## MYLK 1.33 1.59 0.69 0.13 0.68 1.44 0.61
## ZC3H15 57.42 62.97 53.09 82.39 62.86 71.62 53.57
## MAP2K4 17.18 15.92 13.04 26.12 18.33 20.64 16.82
## TMEM206 9.18 9.34 6.98 8.03 10.35 12.12 8.84
## SNAP91 14.39 12.04 10.14 26.17 21.35 25.26 24.48
## SLK 16.37 16.08 11.71 30.62 20.89 22.54 18.46
## CYB5R4 2.46 2.43 2.20 5.16 3.55 3.45 3.06
## COL17A1 0.05 0.13 0.02 0.09 0.01 0.06 0.05
## GSTO2 56.65 53.03 49.40 27.72 39.01 47.11 43.25
## SEC61A2 6.62 6.03 4.83 9.61 7.90 7.53 7.78
## PRKCQ 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TLE2 14.54 21.60 17.86 6.89 13.46 9.83 14.83
## ASB1 18.09 17.15 21.92 29.18 18.66 18.81 18.17
## FAM107B 18.43 18.98 14.09 17.87 14.62 15.78 15.50
## ME1 7.86 4.97 5.28 10.27 13.14 13.97 10.53
## TBC1D1 18.07 15.31 14.90 12.19 17.48 15.86 16.11
## CDK13 14.18 15.60 11.61 28.35 18.41 16.29 16.14
## MTHFD2 186.48 169.42 149.01 265.23 232.12 200.95 220.55
## SLC9A7 3.31 3.12 2.11 4.84 5.03 4.68 4.22
## FOXJ2 14.96 13.14 9.63 20.20 16.70 17.53 18.21
## YBX1 824.81 848.79 715.18 645.20 836.78 872.57 685.44
## PDE4A 5.66 7.47 6.00 3.28 5.33 6.00 6.80
## PPP2R5A 31.78 24.38 24.33 57.62 46.03 47.27 37.85
## CTNNA2 0.67 0.52 0.46 0.51 0.47 0.55 0.57
## ELAVL1 60.44 69.69 56.15 48.63 60.08 60.66 56.98
## TIE1 0.04 0.04 0.00 0.30 0.08 0.15 0.10
## DIP2B 14.37 14.53 10.15 25.92 17.26 20.49 17.35
## SMARCD1 51.39 56.93 47.23 63.65 47.21 53.41 53.20
## KDM4A 13.66 16.20 11.95 31.25 18.04 17.82 18.91
## NFYC 23.23 27.67 24.15 16.15 20.01 20.97 20.98
## ZMYND12 2.41 1.07 1.02 0.59 0.81 1.22 1.14
## SLC9A3 0.10 0.23 0.16 0.06 0.14 0.30 0.19
## NGEF 4.28 4.07 3.65 3.65 4.08 4.09 5.35
## ASPM 13.79 17.66 13.88 7.38 9.38 10.44 13.59
## CD84 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ELOVL1 148.93 148.24 132.63 183.71 174.38 186.51 145.54
## SPI1 0.74 0.24 0.26 0.19 0.26 0.18 0.20
## ZNRD1 44.13 38.32 43.64 52.41 46.46 46.34 41.04
## MPPED2 0.29 0.29 0.25 0.11 0.20 0.49 0.42
## CLDN18 0.02 0.01 0.04 0.00 0.00 0.03 0.03
## ZBTB11 9.64 12.12 8.01 18.00 13.93 15.18 13.73
## ATXN3 14.95 11.26 8.97 18.06 14.10 19.25 16.91
## GOLGA5 22.45 23.49 20.02 37.44 24.00 25.43 26.85
## FGFR2 0.01 0.01 0.00 0.00 0.00 0.00 0.03
## LRRC40 18.76 20.82 14.15 22.52 20.04 21.14 18.43
## ISOC1 35.40 43.76 33.64 28.69 36.66 36.65 33.71
## EML1 4.74 4.55 3.39 2.02 4.06 4.87 2.71
## TRMT11 10.95 13.15 12.28 7.44 10.01 11.26 12.31
## THUMPD1 22.26 25.96 19.65 32.53 22.49 24.89 24.44
## MSANTD3 12.14 13.24 11.05 9.68 10.36 11.92 11.75
## KIF26A 0.15 0.18 0.08 0.09 0.04 0.08 0.06
## ATG2B 3.56 4.66 3.44 10.24 5.96 5.92 6.70
## ARFGEF1 19.60 24.33 17.05 26.06 22.73 25.81 23.75
## ACSM2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZFAT 2.34 4.37 3.26 1.34 3.16 3.59 3.54
## MTFR1 27.88 31.53 24.36 40.10 33.05 37.56 31.92
## STAG3 1.90 2.23 1.15 3.57 2.01 2.57 2.23
## FECH 55.68 65.75 39.18 71.24 71.55 84.80 64.32
## MYO9A 5.01 5.12 3.24 9.90 7.03 7.92 7.79
## DDX3Y 20.93 24.48 17.95 37.87 28.06 29.78 30.17
## PFKP 12.79 7.36 6.50 8.89 7.60 9.86 9.07
## IDI1 83.12 93.25 70.27 153.77 111.80 123.81 121.20
## SP100 0.07 0.32 0.14 0.33 0.06 0.08 0.02
## KLF6 7.68 7.38 4.82 23.64 18.67 14.96 14.27
## PPAP2A 33.59 60.02 51.31 10.30 22.37 28.14 30.97
## NEO1 8.25 9.31 6.76 12.80 9.92 11.54 14.62
## TRAM1 74.94 77.32 52.29 93.81 79.24 93.49 71.98
## PHKA1 11.17 11.55 8.61 9.48 11.73 13.68 11.98
## TNFRSF1A 72.55 70.77 65.80 160.63 120.17 106.78 96.38
## CACNB1 2.88 2.23 2.23 4.41 2.76 2.52 3.38
## EVI5 3.43 3.89 2.20 4.12 5.06 4.99 3.79
## STOML1 10.12 9.51 9.32 9.85 12.91 13.33 10.75
## PKM 604.54 548.61 460.44 626.68 574.29 591.09 693.40
## DHX29 15.24 15.58 11.61 22.66 15.29 20.14 15.25
## DNTTIP2 55.14 49.64 49.59 105.41 57.04 64.72 46.36
## METTL22 10.96 11.10 12.82 19.48 11.42 13.48 11.11
## TP53BP1 17.36 16.39 12.93 21.38 19.15 18.81 17.25
## TRO 0.09 0.10 0.07 0.02 0.05 0.09 0.11
## RRP15 41.46 45.34 28.71 30.16 40.38 48.01 30.03
## RHOA 413.46 419.72 357.21 477.03 511.77 504.23 402.21
## DHX8 27.60 30.00 27.87 41.30 30.23 32.34 30.99
## PRKCZ 11.38 13.08 11.12 19.82 15.56 14.02 14.97
## ZFY 3.37 4.86 3.38 4.70 3.47 4.39 3.55
## IARS2 100.05 129.31 99.72 61.48 101.37 112.16 115.29
## SYT1 0.32 0.28 0.30 0.35 0.23 0.39 0.32
## NAV3 0.26 0.24 0.29 0.03 0.17 0.08 0.30
## IDH3G 47.79 50.83 49.35 45.01 49.84 51.95 53.02
## ROGDI 36.90 27.67 28.30 14.78 30.64 33.84 27.79
## PDZD4 2.07 1.83 1.99 1.32 1.69 1.54 1.79
## ATP2B3 0.07 0.11 0.08 0.00 0.04 0.06 0.08
## ROCK1 16.17 15.68 10.18 23.40 18.79 19.59 17.55
## CBFB 34.25 31.49 26.92 54.74 42.57 43.73 35.92
## PDK3 5.74 4.72 3.66 2.05 4.95 5.42 7.27
## HYAL2 27.74 36.78 32.97 23.86 27.46 32.30 24.59
## HDAC4 1.68 1.62 1.07 2.15 1.67 1.78 2.30
## RASSF1 25.01 24.22 23.71 31.21 20.47 20.95 21.38
## FGFR3 23.85 27.10 21.51 21.67 24.38 25.34 25.89
## IFI35 11.08 6.72 7.43 6.74 8.40 8.77 6.47
## HEATR6 9.26 9.18 7.04 5.33 6.88 8.53 7.71
## COASY 73.06 124.94 104.05 62.53 61.01 66.10 56.35
## PLEKHH3 46.93 46.24 43.50 61.95 67.83 62.08 62.69
## MEF2A 9.88 10.21 6.27 19.41 11.48 14.02 13.30
## OTUD5 26.63 27.71 26.95 40.76 28.35 28.33 29.42
## TFE3 10.98 10.65 8.92 31.71 15.19 14.44 13.66
## TBC1D25 4.40 6.03 5.11 6.20 6.73 5.42 7.49
## ACSL4 1.62 1.66 0.82 0.90 1.54 1.73 1.66
## INPP5A 6.63 5.34 5.82 16.74 10.76 11.97 8.51
## GPKOW 27.76 26.22 24.21 34.97 31.79 32.87 24.28
## GRIPAP1 25.79 26.36 23.71 22.76 26.25 27.13 27.58
## FTSJ1 43.79 48.71 42.16 19.02 34.63 41.54 33.13
## PRR11 8.78 10.48 5.74 3.04 5.43 7.02 8.27
## REEP1 3.64 2.69 2.34 2.16 3.44 3.83 3.95
## ATP11A 0.31 0.13 0.09 0.01 0.03 0.14 0.18
## POLR1A 9.24 8.89 6.21 9.42 9.46 10.43 8.34
## LAPTM4A 114.73 125.80 108.95 242.96 169.19 159.73 142.20
## TTC7A 2.60 2.39 1.66 1.46 1.93 2.27 2.36
## IP6K2 57.93 62.01 62.67 126.39 61.50 66.97 61.60
## STON1-GTF2A1L 0.00 0.00 0.00 0.04 0.00 0.00 0.00
## SRBD1 4.87 4.24 3.73 4.41 5.77 6.36 6.19
## CYFIP1 58.39 59.74 52.60 49.49 63.30 66.43 60.94
## KIF2A 23.30 26.41 15.82 35.67 25.33 27.79 23.30
## RASGRP2 2.26 2.89 3.24 0.62 1.03 1.47 1.21
## PSME4 29.65 29.79 30.04 57.63 42.43 41.44 31.28
## IFT80 12.18 14.45 10.21 15.54 13.39 14.02 15.88
## SIRT2 28.64 33.26 30.67 36.93 33.97 33.88 34.70
## ERLEC1 25.60 26.05 23.39 28.67 32.25 32.56 28.93
## PPP2R5B 4.85 5.47 4.49 7.92 6.91 7.52 8.74
## PYGM 0.23 0.20 0.12 2.03 0.20 0.20 0.23
## PAGE1 0.14 0.32 0.10 0.06 0.53 0.06 0.10
## PITX1 7.65 8.63 8.45 4.99 8.13 8.53 6.84
## TRPC7 0.00 0.04 0.00 0.00 0.00 0.00 0.00
## MAST4 1.49 1.32 0.95 3.21 1.85 2.03 1.94
## GPR116 0.05 0.12 0.16 0.01 0.14 0.22 0.09
## SDK2 0.02 0.01 0.01 0.00 0.00 0.08 0.02
## ADAM7 0.02 0.03 0.03 0.02 0.02 0.03 0.01
## NUP133 48.11 56.84 44.02 53.61 50.50 54.44 55.80
## NUCKS1 259.04 255.19 174.11 157.34 222.82 241.47 204.00
## VPS35 61.56 64.31 47.52 79.22 74.57 79.05 70.03
## DNAJA2 61.07 66.21 54.99 81.53 74.34 79.24 59.97
## BCL3 14.11 12.95 15.26 8.36 13.56 13.56 11.76
## KCNAB2 4.38 3.87 3.83 1.79 3.17 4.33 3.63
## ABCC9 0.06 0.16 0.09 0.01 0.03 0.03 0.03
## GAL 57.84 42.26 36.49 22.31 38.04 46.74 22.78
## CLEC2D 0.73 0.83 1.03 0.63 0.64 0.56 0.61
## FUNDC1 22.13 18.98 18.80 21.37 17.74 19.36 18.31
## MAOB 0.11 0.09 0.09 0.10 0.17 0.18 0.21
## RORA 0.64 0.41 0.24 0.51 0.15 0.55 0.49
## DRD4 1.71 1.61 2.01 2.35 1.43 1.56 2.24
## TGFBR3 0.81 0.80 0.63 0.56 1.11 1.37 1.49
## KIAA1107 1.94 1.57 1.15 2.48 2.52 2.63 2.68
## PLA2G10 0.55 0.73 0.72 0.44 0.40 0.46 0.53
## HES2 0.66 0.29 0.55 0.39 0.63 0.68 0.49
## ATP1B3 61.63 62.94 56.98 114.37 64.23 60.48 47.68
## NEDD4 5.56 4.75 3.00 8.80 7.34 6.63 6.27
## PIGB 10.97 13.52 13.55 5.47 7.43 9.63 9.27
## MAPK6 29.16 26.79 19.66 88.05 48.40 51.46 44.62
## GNB5 9.60 7.27 6.51 8.14 10.94 9.66 10.50
## RAB27A 9.45 9.90 6.07 10.64 9.67 9.29 10.60
## CECR5 54.09 56.45 55.17 30.35 48.24 56.23 52.52
## UFD1L 111.89 98.70 83.21 142.66 149.39 137.35 115.35
## LRP6 6.65 6.46 4.71 7.64 7.95 7.74 7.16
## GUCY2C 0.26 0.09 0.13 0.05 0.02 0.17 0.03
## SCT 0.33 0.26 0.92 0.14 0.00 0.86 0.52
## PHRF1 12.93 13.88 11.09 14.92 13.73 13.06 13.11
## IKBKAP 21.44 22.56 17.60 18.79 24.58 26.37 21.24
## NUCB2 132.19 126.67 105.44 94.57 130.72 133.55 125.80
## PFN2 125.36 92.73 78.43 52.39 104.78 128.29 99.89
## PTPN3 15.45 13.13 10.19 16.25 15.80 17.65 14.46
## SPTB 1.38 1.82 1.70 1.31 1.34 1.28 1.69
## DAPP1 0.21 0.11 0.06 0.62 0.33 0.20 0.08
## FGF10 0.03 0.23 0.11 0.00 0.05 0.06 0.15
## SLC44A1 16.07 18.01 12.08 15.05 18.77 18.55 21.43
## TMEM260 6.03 6.97 5.91 8.85 9.19 7.92 9.40
## SMG6 12.14 15.01 12.75 23.99 16.16 16.43 18.46
## EXOC5 37.41 31.08 22.36 55.86 41.83 43.65 36.86
## CLTCL1 7.89 8.24 8.52 3.11 3.76 4.92 4.10
## FGF22 0.80 0.88 1.10 1.56 0.68 0.62 1.02
## FSTL3 20.97 13.48 11.59 10.39 14.16 18.92 14.49
## DGCR2 23.90 31.47 23.68 37.26 26.69 29.74 28.82
## RNF126 50.33 66.15 60.87 40.46 38.59 43.04 37.57
## MNT 8.11 10.52 8.24 18.20 14.08 13.14 16.57
## ZXDC 11.93 11.60 10.07 15.33 11.51 12.84 13.36
## JMJD6 21.35 17.79 19.37 54.57 29.13 25.79 25.45
## POLB 39.20 35.87 35.92 78.23 47.24 48.97 39.22
## ST6GALNAC1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## WIPI1 11.37 7.67 6.36 33.22 18.54 19.75 17.50
## FRMPD1 0.35 0.46 0.26 0.18 0.24 0.36 0.45
## GBA2 43.24 48.00 50.05 59.11 48.95 50.35 46.43
## NDST1 15.48 20.00 13.85 7.84 11.79 14.84 13.79
## ASNS 135.44 105.13 104.30 273.36 220.58 187.86 231.65
## AP3M2 20.49 18.89 14.12 13.71 17.81 18.66 17.96
## CNGB1 0.00 0.00 0.00 0.00 0.00 0.00 0.05
## ST6GALNAC2 2.26 1.41 1.63 1.56 1.77 1.69 2.16
## CHAT 0.00 0.00 0.00 0.00 0.02 0.00 0.00
## PABPC1 705.30 753.18 622.98 841.69 831.33 833.48 890.94
## TESK2 2.59 3.32 2.87 3.86 3.24 3.31 4.10
## C16orf80 46.78 49.61 45.49 54.59 47.09 51.98 44.34
## CSNK2A2 32.75 33.21 27.58 44.12 33.74 34.36 35.58
## PTPN21 1.27 1.48 0.87 1.64 1.70 1.58 1.26
## EIF2B3 34.14 27.30 24.99 21.36 34.51 38.67 26.81
## CAMK2A 0.02 0.01 0.00 0.00 0.00 0.00 0.00
## TCOF1 39.73 40.31 33.15 15.67 33.54 27.67 29.49
## CDC42 198.05 194.56 151.94 313.28 222.08 249.63 193.35
## OSBPL3 6.13 8.07 5.94 3.63 6.10 7.79 6.34
## EPHA8 0.26 0.39 0.20 0.04 0.08 0.10 0.16
## SLC12A3 0.00 0.00 0.00 0.00 0.00 0.05 0.00
## RAD18 13.85 12.05 8.91 16.30 14.07 14.19 14.15
## ATP2B1 24.25 27.14 21.29 36.97 31.56 33.65 28.67
## TRPM5 0.00 0.02 0.01 0.00 0.00 0.00 0.01
## NCK2 4.37 5.37 5.10 4.58 5.18 4.70 5.67
## MAP4K4 17.13 15.78 11.19 28.25 20.09 22.99 20.02
## MGAT4A 4.14 3.56 2.79 3.56 4.57 5.27 4.57
## RPL31 2666.70 2710.63 2936.30 2279.69 2325.13 2686.27 2475.38
## WDR1 113.51 97.03 85.81 156.23 135.79 125.48 102.04
## SNX13 20.42 21.58 14.71 30.05 26.46 30.31 25.83
## MS4A12 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ARHGAP10 3.95 3.51 4.01 2.25 3.45 4.21 3.94
## RPS6KA2 0.40 0.29 0.23 0.61 0.41 0.30 0.47
## ING3 22.68 25.18 18.72 22.36 24.00 25.05 22.02
## VASH1 0.92 0.98 0.60 0.27 0.36 0.51 0.77
## LMCD1 0.27 0.17 0.00 0.14 0.22 0.15 0.21
## WBSCR22 262.40 226.59 213.01 239.97 252.59 269.04 182.19
## SEL1L 20.14 22.97 14.44 41.20 24.02 30.63 28.69
## TRIP13 42.66 44.35 32.29 12.82 29.16 29.88 26.48
## ATP6AP1 103.85 112.86 102.76 147.12 121.15 121.68 109.98
## TCF3 42.91 50.18 42.82 42.98 45.48 43.55 47.49
## TRIB2 0.06 0.17 0.10 0.06 0.00 0.00 0.01
## DAZAP1 137.41 157.69 142.81 81.39 136.91 138.10 138.03
## MBD3 63.90 82.12 84.66 41.65 54.45 59.05 62.73
## PRLH 0.00 0.50 0.26 0.81 0.00 0.00 1.06
## HLTF 47.87 51.42 38.22 21.49 43.12 48.40 49.81
## FAM50A 72.56 68.06 75.79 64.47 74.93 74.06 72.14
## FAM3A 39.92 35.19 34.72 34.09 42.65 42.20 39.40
## CPSF1 50.74 61.96 77.95 40.75 43.22 41.01 55.52
## MYO3B 0.00 0.00 0.00 0.00 0.00 0.00 0.02
## CYBRD1 0.02 0.02 0.01 0.01 0.02 0.01 0.00
## CDH19 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PDCD2 82.52 93.83 92.55 63.07 76.09 83.81 68.37
## SLC6A15 10.19 11.24 9.60 7.06 10.62 11.85 10.41
## RDH11 101.24 133.10 99.64 99.96 110.14 112.70 151.90
## PRKACA 66.79 66.87 48.98 78.75 77.32 75.92 70.04
## LPHN1 17.38 24.72 17.20 8.69 14.07 15.87 16.78
## SPP2 0.00 0.00 0.12 0.00 0.00 0.00 0.00
## ACTN1 41.78 48.00 33.48 50.70 47.66 46.15 44.93
## ZFYVE26 3.31 3.41 2.37 8.04 4.28 4.14 4.16
## RPS6KA6 7.57 8.04 4.41 10.03 10.43 12.11 9.70
## EPN2 14.19 19.06 15.37 12.25 12.71 14.14 15.29
## PTPN18 69.17 77.41 65.77 34.44 51.98 57.96 60.29
## LIMS2 0.00 0.05 0.00 0.00 0.01 0.09 0.00
## ASIC4 0.07 0.00 0.02 0.14 0.03 0.03 0.03
## SPEG 0.39 0.76 0.39 0.25 0.49 0.27 0.33
## LNX1 3.61 3.08 2.41 2.22 3.13 2.92 3.02
## ALDH3A2 533.38 661.01 488.29 348.35 583.28 683.99 649.80
## TFRC 74.13 112.18 74.41 114.87 91.49 95.89 95.32
## SREBF1 53.62 126.66 92.96 34.00 50.39 46.97 135.68
## TRPC5 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## AFF4 14.38 13.23 8.58 48.09 21.46 23.04 21.34
## UBE2D1 9.83 11.53 9.41 28.56 13.69 12.93 9.90
## MPP5 11.13 12.43 8.61 15.56 15.31 14.11 12.58
## RHOBTB1 3.48 3.50 3.64 2.51 2.13 3.21 2.26
## SMC1A 57.61 67.61 32.66 25.42 54.54 57.38 55.81
## HSD17B10 194.40 182.28 185.05 196.73 237.99 239.84 186.04
## MARK2 22.11 25.87 18.99 32.30 24.89 24.70 25.71
## HMMR 38.61 49.98 35.50 26.36 31.17 28.89 40.12
## CHFR 19.81 19.95 17.63 39.01 19.06 20.88 16.66
## TRHDE 1.30 1.57 1.10 0.54 1.01 0.91 0.85
## P4HA2 4.47 3.19 2.09 8.92 6.46 4.44 8.92
## FCGR2B 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## NFATC3 10.35 10.75 6.64 12.37 10.94 13.26 11.72
## TRNT1 19.56 22.10 18.69 21.64 20.05 18.15 15.11
## ACADVL 387.34 429.47 510.53 345.22 309.58 341.02 351.82
## STK10 5.01 5.93 4.17 14.39 8.68 7.91 5.66
## FBXW11 17.39 23.55 15.96 28.45 24.70 24.37 26.63
## ACAP1 2.67 2.51 1.66 2.45 1.70 1.58 2.27
## CRMP1 1.63 1.73 1.14 1.51 1.90 1.76 2.41
## EVC 2.81 3.54 2.27 2.84 2.86 2.84 4.32
## DERL2 73.26 51.71 57.45 92.59 65.74 80.03 55.56
## SIDT1 0.32 0.11 0.06 0.06 0.14 0.26 0.37
## NDE1 25.46 27.50 15.37 23.78 27.02 24.42 28.51
## MRVI1 0.00 0.00 0.00 0.00 0.00 0.01 0.02
## TMEM38A 1.30 1.85 1.20 0.92 0.88 1.43 1.14
## AP1M1 29.65 28.17 26.41 28.50 30.15 31.30 26.62
## PVR 49.61 40.56 31.73 62.48 59.13 59.29 40.57
## IKBKG 11.64 9.15 10.04 25.41 12.58 11.62 12.76
## XRCC1 16.10 20.70 17.30 9.42 14.60 14.79 15.64
## SCARB1 101.07 123.86 106.12 58.09 98.58 112.00 105.32
## CYP2W1 0.03 0.15 0.01 0.12 0.03 0.00 0.08
## MCM2 95.28 105.53 81.00 52.38 82.15 76.39 89.28
## MOV10L1 4.77 2.00 3.25 2.65 3.72 4.35 3.44
## PANX2 8.67 6.84 6.37 13.57 16.31 15.27 13.86
## SELO 26.80 38.33 40.53 31.49 29.69 26.93 30.13
## TP63 0.00 0.01 0.00 0.00 0.00 0.00 0.01
## ALPK1 4.09 3.11 2.57 6.30 4.00 3.69 4.93
## LLGL2 79.82 89.73 81.85 98.96 92.89 86.42 83.32
## PDE8A 11.98 11.82 9.23 10.52 13.61 13.95 12.96
## CLCN4 0.65 0.95 0.63 0.46 0.50 0.95 0.60
## NLE1 22.47 25.93 23.86 6.64 17.99 20.89 17.14
## SDHA 127.50 138.32 138.26 126.77 121.45 123.67 118.46
## SMARCE1 140.53 148.03 116.16 108.00 124.14 142.60 125.67
## FNDC8 0.19 0.08 0.13 0.10 0.05 0.09 0.23
## GSDMB 3.98 4.92 8.32 5.90 5.58 3.80 11.29
## KDM5A 13.75 14.09 8.99 32.77 16.30 20.17 16.47
## ADAM11 3.45 4.10 3.02 1.45 2.33 3.05 3.74
## PPP2R3A 1.70 1.47 1.15 1.92 1.59 1.84 2.10
## FERMT2 12.83 14.60 10.40 22.53 18.02 16.42 15.41
## ABCB11 0.00 0.00 0.00 0.01 0.00 0.01 0.00
## DHRS9 0.05 0.00 0.00 0.14 0.00 0.05 0.06
## CD5L 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PTGS2 0.26 0.14 0.22 0.20 0.17 0.29 0.24
## IGF2BP2 3.25 3.09 2.74 8.60 5.42 4.52 5.02
## MAP3K13 29.97 22.67 21.00 40.73 33.27 34.60 29.19
## ST6GAL1 8.50 13.09 9.93 4.54 6.73 6.49 10.31
## TBX21 0.00 0.00 0.02 0.01 0.01 0.04 0.01
## FRY 6.71 5.18 4.69 5.79 7.47 8.18 6.78
## PICALM 83.69 83.60 62.60 145.66 109.19 121.51 96.42
## NSF 34.37 30.51 22.61 53.10 41.01 46.49 35.96
## GLI2 0.03 0.02 0.01 0.07 0.06 0.09 0.07
## CLASP1 5.70 5.66 4.04 7.53 5.87 6.90 6.51
## MRPS34 196.30 231.88 236.48 62.55 137.97 163.77 132.01
## NOTCH3 6.94 10.26 7.94 6.09 6.25 5.85 9.24
## CLNS1A 227.41 248.63 234.97 160.00 218.74 242.30 206.63
## PPP2R2C 2.57 1.52 1.22 2.97 4.13 5.05 4.25
## TEAD2 26.65 42.21 34.09 13.94 26.82 22.52 29.23
## EED 27.80 23.97 20.85 26.70 28.93 26.69 22.54
## CDHR2 0.17 0.75 0.44 0.25 0.14 0.13 0.63
## SNCB 2.11 2.03 1.81 0.09 0.65 1.07 2.83
## TSG101 85.17 98.90 96.27 120.36 98.47 111.79 87.93
## C17orf85 18.74 18.63 14.80 43.66 20.05 19.12 20.06
## ATP2A3 0.60 0.45 0.36 0.25 0.56 0.41 0.35
## CA12 15.13 14.38 11.28 9.83 16.89 20.04 14.05
## MGLL 5.15 6.87 3.56 2.59 3.44 3.28 3.45
## NTN4 0.25 0.17 0.30 0.27 0.38 0.43 0.10
## BCS1L 48.81 50.21 49.85 57.06 60.12 56.64 51.35
## NUAK1 0.86 1.10 0.68 0.63 0.31 0.32 0.65
## DPP8 11.05 13.31 10.16 13.71 9.99 12.78 10.96
## SLC24A1 2.67 2.75 1.42 2.84 2.61 3.11 4.70
## ZNF532 3.06 2.63 1.67 0.58 1.98 2.02 2.88
## SCARF1 0.34 0.47 0.62 2.71 0.71 0.51 0.87
## LMAN1 18.17 20.83 15.39 12.37 18.78 19.37 21.48
## PTPLAD1 131.72 137.68 101.81 78.27 127.75 133.43 123.95
## IPCEF1 0.04 0.03 0.12 0.10 0.08 0.02 0.35
## ZZEF1 5.60 6.34 4.09 9.29 7.43 8.32 8.28
## NOX3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ENO1 1045.50 904.56 803.64 828.00 1007.47 1021.49 1139.16
## SLC12A1 0.02 0.01 0.01 0.01 0.00 0.00 0.03
## C19orf10 161.29 154.14 151.85 137.77 160.24 167.84 137.79
## ANO8 6.77 7.80 5.96 3.89 5.94 7.15 9.58
## TUBE1 14.42 11.59 9.70 26.66 21.09 17.71 17.30
## ARHGEF10L 6.83 7.72 7.35 6.05 7.33 7.26 8.64
## TXK 0.09 0.01 0.12 0.25 0.08 0.11 0.16
## WSCD2 0.00 0.00 0.02 0.00 0.01 0.00 0.00
## KCNQ2 4.21 3.45 3.37 0.70 1.56 2.80 3.08
## TACR2 0.31 0.34 0.27 0.26 0.25 0.28 0.30
## ACTR6 54.26 50.72 45.05 86.52 72.03 76.05 63.78
## TIPIN 40.21 34.33 29.67 28.01 36.68 40.37 31.98
## SRI 110.45 104.80 105.17 100.38 113.31 115.19 95.15
## EIF4G3 20.95 23.88 15.93 11.27 19.50 23.99 22.42
## NUP37 79.66 76.48 65.78 59.35 70.45 75.88 71.58
## SEMA3A 0.00 0.07 0.01 0.00 0.00 0.01 0.00
## GTSE1 17.56 24.52 17.14 8.06 12.35 11.07 15.29
## SEMA3C 29.17 19.89 15.91 16.01 25.40 36.22 24.30
## TTC38 19.21 23.04 18.71 21.87 17.68 18.97 19.02
## ACAT1 68.21 79.49 65.48 54.55 66.77 69.12 67.15
## GRAMD4 6.55 9.10 7.73 9.79 9.42 10.54 8.69
## CELSR1 9.85 10.17 8.80 6.20 8.80 10.09 9.57
## WNT8B 1.56 2.49 1.13 0.16 0.45 0.90 0.85
## ZNF638 60.86 57.51 63.24 74.97 60.23 55.24 58.86
## SLC25A40 26.00 28.92 18.69 22.27 30.64 28.45 30.38
## TIMM21 37.95 35.82 31.67 25.19 31.57 36.18 30.60
## ADD2 0.00 0.00 0.00 0.01 0.00 0.00 0.01
## FGF4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RASAL2 3.17 3.21 1.78 2.98 3.32 4.09 3.36
## VPS9D1 7.73 8.25 7.84 6.83 7.25 7.64 10.43
## ZNF37A 7.13 6.51 4.45 8.18 7.18 8.05 6.51
## MARK3 42.06 39.89 40.31 65.39 49.27 46.89 47.37
## SLC25A3 911.82 1020.85 929.38 1104.47 1014.96 1095.74 913.52
## FNDC3B 4.98 4.04 2.71 7.35 6.71 5.83 5.30
## FOSL2 3.63 2.38 2.04 26.33 6.17 5.75 5.73
## CACNG5 0.00 0.00 0.02 0.05 0.04 0.04 0.04
## CACNG4 0.31 0.68 0.40 0.09 0.16 0.21 0.23
## FRYL 10.35 9.28 8.00 22.49 13.42 14.50 11.81
## TMEM131 7.26 9.69 6.51 12.85 11.46 12.18 12.44
## FSCN1 4.31 5.01 4.92 8.00 3.76 4.04 5.58
## ACTB 2001.04 1748.04 1644.55 1279.22 2149.35 1913.00 1424.48
## MOCOS 6.47 5.52 5.52 8.96 7.08 7.21 5.72
## PLD1 0.23 0.17 0.40 0.31 0.53 0.96 0.46
## ATP12A 0.26 0.37 0.28 0.10 0.10 0.12 0.19
## WDR62 7.93 9.20 8.52 9.00 9.34 7.41 10.96
## DLG1 37.42 46.44 27.22 32.24 44.21 47.93 47.53
## RAB7A 170.67 178.33 152.03 319.63 216.51 227.69 185.40
## BCAP29 45.31 51.41 31.62 41.23 46.90 53.61 43.63
## SEC31B 3.40 2.58 3.30 2.38 1.74 1.77 3.81
## SART3 38.72 43.70 34.44 59.62 45.67 41.84 46.06
## ARHGAP15 2.67 3.54 3.44 1.62 2.67 2.90 2.38
## TUBA3D 0.31 0.75 0.80 0.07 0.23 0.16 0.25
## PAX2 0.49 0.77 0.59 0.37 0.57 0.50 0.62
## EXOSC7 65.84 61.85 62.93 56.77 64.95 65.69 52.62
## KIFAP3 44.02 38.20 34.35 54.62 52.41 58.03 44.29
## MKRN2 15.24 13.25 10.97 31.95 20.11 21.03 20.09
## MCM6 49.34 52.41 42.31 26.91 37.81 40.26 40.52
## REXO2 60.74 60.93 58.35 63.76 71.68 83.17 62.12
## RBM7 15.51 15.56 12.29 19.42 16.72 18.87 17.90
## RBMS2 2.93 3.18 2.20 1.83 2.37 3.64 3.10
## BAZ2A 47.90 53.03 31.01 83.24 61.06 68.47 72.05
## PTPN23 16.57 19.94 14.43 27.57 20.87 21.14 25.70
## MLH1 50.70 51.55 43.75 56.74 57.84 59.62 57.07
## UNG 162.72 199.36 164.11 63.41 121.45 127.53 145.24
## FMO4 2.17 1.54 2.14 1.15 1.20 1.73 1.41
## KLHL20 8.71 8.80 5.63 19.43 10.93 10.85 9.25
## RGS11 10.55 8.94 10.29 6.27 7.55 7.70 12.05
## SLC46A1 17.83 21.34 21.67 12.35 15.83 17.00 17.70
## PLXNA2 5.24 6.15 4.58 9.17 8.50 7.16 7.62
## SPAG5 31.11 47.05 29.34 14.07 26.06 25.19 28.54
## ANKRD13A 22.26 25.93 19.75 40.59 26.02 31.16 30.15
## TPD52 105.54 108.09 87.47 60.77 117.46 116.71 114.32
## ACACB 3.07 3.63 2.85 1.02 2.04 2.21 4.69
## TRAF4 73.69 87.37 79.78 74.29 80.19 91.08 81.83
## PAG1 2.71 3.12 1.45 1.93 3.09 3.59 3.77
## GPATCH1 5.24 4.71 4.52 7.60 5.70 5.80 5.89
## ICAM3 35.82 31.30 27.12 22.09 39.10 38.33 40.84
## NT5C2 32.40 28.57 21.75 70.34 39.25 41.16 43.21
## MCAM 1.11 1.34 0.77 0.34 0.44 0.70 0.44
## GPC4 6.75 8.60 5.41 6.94 8.33 7.47 8.93
## MBNL3 1.53 1.33 0.79 0.48 0.89 1.46 0.95
## CAMSAP3 11.96 16.50 15.12 14.93 11.84 10.11 11.96
## RAP1GAP 21.37 27.16 22.35 14.21 20.50 21.89 23.49
## XAB2 33.89 38.27 33.40 50.15 33.20 33.13 34.35
## ARHGEF1 24.70 26.77 25.98 23.70 24.93 32.70 27.92
## STXBP2 58.05 64.42 60.16 92.47 64.65 64.98 69.03
## MAP2K7 17.39 22.67 19.80 18.27 19.82 21.18 22.74
## NMRK2 0.10 0.19 0.08 0.06 0.10 0.15 0.08
## DGKD 6.05 8.65 8.16 6.41 6.39 6.92 7.65
## CTTNBP2 0.27 0.41 0.21 1.07 0.47 0.19 0.58
## ACTL6B 5.53 8.57 7.23 1.86 4.42 3.94 6.36
## RARB 1.65 3.94 2.13 0.42 0.86 1.15 2.48
## TOP2B 87.96 90.44 77.88 97.53 101.63 98.10 88.40
## TM9SF3 64.16 73.24 51.88 118.25 82.91 99.74 76.78
## NFKB2 32.03 26.31 25.05 53.69 41.89 36.32 37.95
## UBE2T 244.32 274.23 251.42 65.90 156.19 166.73 178.91
## PPP1R12B 4.02 5.96 4.10 4.62 5.49 6.87 7.15
## DNAJC10 69.58 59.01 40.52 39.01 58.77 75.48 56.98
## GTF3C1 44.43 52.44 54.83 48.56 53.67 49.11 50.39
## IL4R 1.09 0.60 0.52 0.47 0.73 0.47 0.39
## USP33 23.76 24.69 19.25 30.02 25.99 26.72 27.84
## PAK3 0.14 0.18 0.13 0.07 0.03 0.04 0.14
## CAPN6 0.03 0.00 0.01 0.04 0.02 0.02 0.00
## DCX 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SNRPA 85.16 102.89 101.48 40.04 78.32 79.76 75.08
## SPAG6 0.05 0.00 0.00 0.08 0.04 0.00 0.00
## EXOSC5 52.04 58.23 58.96 22.95 49.31 54.68 45.97
## DYNC1I2 38.11 33.77 25.80 55.38 44.94 53.93 39.23
## APBB1IP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## LRCH4 23.49 29.97 28.55 50.81 28.43 29.09 38.45
## FAM76B 16.73 17.76 12.05 29.98 20.61 22.26 21.55
## SIRT6 23.77 22.86 24.91 43.71 28.39 26.45 28.47
## TYR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## POLD3 24.76 26.41 20.36 16.87 23.37 22.58 23.76
## ACTN2 6.04 4.87 4.79 1.15 2.72 2.77 3.93
## CAPZB 158.56 165.67 150.56 166.10 176.76 181.30 158.15
## GPR137B 6.97 6.82 7.69 12.25 9.04 9.65 9.53
## NAALAD2 0.30 0.23 0.29 1.45 0.40 0.42 0.28
## JADE1 24.02 21.55 17.84 23.72 25.58 27.14 26.86
## SLC25A43 7.68 10.31 6.92 1.98 4.85 5.48 6.42
## UBE2A 45.59 45.35 38.24 101.08 62.79 63.00 46.06
## FGFR1 10.32 7.80 5.30 16.20 12.08 13.09 10.44
## FKBP6 0.22 0.49 0.16 0.14 0.17 0.21 0.34
## GTF2I 125.71 192.14 150.35 88.65 130.35 135.66 138.43
## SMC1B 3.79 2.48 2.11 1.07 2.09 2.39 2.93
## FBLN1 5.76 7.42 5.97 2.31 3.74 3.00 4.76
## ITGA8 0.03 0.18 0.01 0.00 0.00 0.00 0.00
## CST7 0.04 0.00 0.00 0.04 0.07 0.00 0.00
## MAP2 11.94 15.81 10.40 11.34 13.94 14.44 16.04
## PIAS2 11.75 13.17 8.02 12.45 13.44 14.77 11.79
## AMPH 0.56 0.32 0.20 0.18 0.37 0.51 0.45
## ARAF 43.12 48.82 46.52 19.78 39.67 46.15 39.74
## MCCC1 30.43 42.86 41.16 34.76 29.11 33.10 34.18
## LAMP3 0.29 0.12 0.08 2.63 0.95 0.89 1.08
## FAP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NEBL 5.67 5.88 3.49 5.33 6.88 9.59 10.14
## ACER3 7.85 7.78 4.31 11.90 10.81 11.17 8.67
## UBE2K 78.83 73.54 60.28 131.62 100.53 99.23 77.09
## PIK3C3 29.58 29.23 21.60 29.97 29.06 34.15 29.41
## N4BP2 3.83 3.18 1.82 2.99 4.19 4.78 4.31
## C12orf5 7.11 5.03 4.63 15.78 5.66 7.45 3.66
## TULP3 32.83 30.97 23.73 73.57 37.08 34.97 38.85
## SYNJ2 2.55 3.15 2.60 2.67 2.32 3.51 2.50
## ADCY2 0.00 0.00 0.01 0.00 0.00 0.00 0.01
## PPP2R5C 75.48 74.26 60.91 108.07 86.40 91.30 81.03
## RBFOX1 0.01 0.05 0.01 0.00 0.00 0.01 0.00
## GNB1 199.79 208.07 162.95 248.82 230.20 230.42 208.81
## HOXA9 4.02 4.01 3.53 5.10 2.58 3.88 3.04
## EDN1 3.99 3.38 3.86 5.22 7.18 5.15 3.17
## MLLT10 11.80 14.71 9.74 13.66 15.47 15.97 17.53
## ZCWPW1 2.73 1.50 2.23 2.22 2.55 2.14 3.59
## ADCYAP1R1 0.00 0.01 0.01 0.00 0.00 0.00 0.00
## FGF20 0.00 0.02 0.00 0.02 0.02 0.04 0.00
## P2RY10 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ITM2A 0.24 0.04 0.08 0.16 0.23 0.08 0.07
## NRD1 90.89 83.10 75.03 145.18 109.29 102.42 95.93
## VDAC3 232.21 228.65 198.50 175.59 217.37 248.56 196.97
## PCM1 85.34 76.42 80.45 105.33 96.37 100.62 95.74
## TNRC6C 1.89 1.56 0.96 4.22 2.55 1.83 1.95
## CBFA2T2 3.70 4.55 3.51 12.04 6.25 6.41 7.81
## BRINP1 0.72 1.08 0.72 0.20 0.36 0.58 0.46
## ITCH 16.72 17.51 12.60 23.48 18.98 21.57 21.80
## PKD2L2 0.15 0.04 0.05 0.15 0.33 0.17 0.21
## TP53INP2 21.06 15.02 14.77 48.56 21.28 23.01 21.95
## SDF4 108.18 115.17 102.55 139.09 120.13 124.35 109.87
## MYH7B 0.34 0.19 0.16 0.25 0.12 0.09 0.09
## BPIFB2 0.02 0.00 0.01 0.00 0.00 0.00 0.00
## TP73 0.69 0.90 0.79 0.22 0.38 0.62 0.91
## TOLLIP 14.58 16.81 16.01 47.64 20.45 19.47 18.45
## UBE2D4 16.42 17.93 13.01 12.25 17.97 20.14 18.93
## CLUL1 0.83 0.98 0.90 0.97 0.72 0.46 2.40
## RUNX1T1 0.00 0.00 0.01 0.00 0.00 0.11 0.00
## CDH17 3.04 4.12 2.73 3.55 2.90 2.68 3.99
## THOC1 24.91 30.56 32.24 32.49 29.27 23.35 27.58
## FKBP7 2.50 3.80 2.80 0.95 1.76 2.14 2.93
## OSBPL6 1.52 1.52 0.75 2.48 2.52 2.11 2.88
## SLC1A3 4.68 4.06 2.68 5.02 4.21 4.05 4.15
## XRCC5 237.40 240.09 188.16 174.60 210.68 245.33 192.02
## LXN 21.82 17.81 22.75 14.73 16.89 21.51 16.43
## SP140 0.64 0.42 0.21 0.37 0.32 0.67 0.60
## MKNK1 13.12 12.30 10.00 19.51 17.22 14.46 15.06
## TNS1 0.78 0.67 0.35 0.25 0.63 0.74 0.80
## REXO1 13.09 15.12 14.87 22.00 13.81 13.42 15.91
## SAR1A 56.87 53.51 47.22 108.70 62.77 64.70 57.31
## CDC14A 4.67 6.12 3.93 10.02 5.80 6.82 6.63
## RAPGEF3 0.54 0.38 0.44 0.96 0.43 0.38 0.50
## CEACAM1 0.29 0.97 0.26 0.64 0.31 0.49 0.55
## SENP1 20.66 21.45 13.28 19.79 21.19 22.17 22.75
## DUSP13 0.14 0.00 0.00 0.26 0.13 0.27 0.05
## CIC 18.04 21.56 17.58 25.68 19.08 19.39 25.23
## LIPE 3.74 5.72 4.60 1.48 3.33 2.78 5.73
## FDFT1 280.83 343.57 264.97 430.91 378.24 406.36 450.29
## PAFAH1B3 129.96 168.91 155.10 45.48 103.76 99.07 111.37
## OPHN1 0.92 1.19 0.65 1.30 1.60 1.52 1.59
## AFM 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## KIF22 97.68 104.23 103.63 71.03 85.99 72.83 87.90
## SCGN 1.91 3.15 2.60 0.95 1.25 1.69 1.12
## LRRC16A 9.98 9.52 7.43 7.36 8.69 9.05 9.66
## PGM1 17.30 16.43 13.80 7.94 14.87 16.42 18.41
## DDX1 88.03 99.38 82.82 79.70 93.22 111.27 84.54
## DNM2 79.14 89.59 77.13 114.01 83.11 83.87 94.14
## EPB41L2 6.33 6.50 3.42 2.35 3.72 4.52 5.27
## RIMS1 1.42 2.35 1.01 0.24 0.83 0.93 1.01
## MOXD1 5.42 3.84 2.93 3.65 4.50 3.78 4.06
## STX7 9.87 10.92 8.20 11.94 13.63 13.27 12.67
## RABL2B 18.26 14.41 12.34 16.92 15.82 17.87 15.20
## KEAP1 58.32 56.11 56.59 68.64 75.05 79.56 59.22
## DDX43 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PTPRH 0.84 0.27 0.42 2.72 1.12 1.12 0.66
## DCT 0.18 0.11 0.11 0.05 0.06 0.17 0.30
## SLC35C2 46.80 42.58 42.22 36.99 42.61 49.82 40.91
## CRYBG3 5.36 7.08 5.51 6.58 7.65 7.88 7.72
## EPHA6 2.93 3.85 2.02 1.06 2.02 2.22 3.25
## SCTR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RFX3 1.68 2.02 1.60 1.44 1.93 2.45 2.22
## RIF1 6.54 6.81 4.17 6.24 6.24 7.11 5.62
## RAB21 68.54 62.39 50.15 129.82 95.89 99.23 81.63
## SLC4A4 0.58 0.55 0.42 0.25 0.35 0.43 0.45
## SMARCA2 57.38 53.65 48.15 73.65 67.96 68.17 70.69
## RDH8 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SESN1 4.93 5.50 5.08 17.69 8.51 11.99 10.05
## MID2 3.14 2.05 1.23 6.82 3.73 4.00 3.24
## PIH1D3 0.76 0.06 0.03 0.18 0.25 0.26 0.23
## COL5A3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SRCAP 18.32 20.22 13.66 22.19 20.83 20.14 22.72
## KIAA0020 49.51 48.21 43.96 40.30 52.45 56.13 39.40
## CPB2 0.02 0.02 0.00 0.02 0.00 0.02 0.02
## CHRNA3 2.90 2.64 1.78 4.11 4.27 3.40 2.93
## KCNN2 3.54 4.81 3.94 1.77 2.70 3.88 3.70
## CNOT4 9.97 9.13 7.02 22.32 11.77 11.74 11.37
## PSEN1 24.68 21.63 18.28 70.52 33.23 34.98 29.95
## CPOX 12.99 14.45 12.13 10.29 14.12 14.24 15.97
## CLDND1 56.03 53.66 45.94 85.22 60.01 68.69 67.90
## MOK 24.33 18.20 21.50 24.90 21.14 20.54 20.28
## HSP90AA1 952.95 779.32 612.50 1692.66 1357.73 1142.51 987.65
## RBL1 7.31 7.27 5.00 6.24 8.09 8.37 9.91
## DLGAP4 15.26 16.10 13.10 31.38 18.79 18.49 18.15
## IGSF9B 0.09 0.06 0.00 0.04 0.08 0.02 0.01
## CFHR2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NDC80 38.80 40.38 36.17 17.41 27.64 26.96 32.49
## AP4E1 6.32 6.08 4.19 8.90 6.54 7.65 5.81
## RSBN1 3.57 3.68 3.59 9.06 5.32 5.31 5.06
## MAGI3 5.77 5.56 3.68 11.49 7.32 7.60 6.41
## CXCL2 0.08 0.00 0.00 0.81 0.16 0.03 0.00
## AFP 0.06 0.15 0.01 0.00 0.02 0.11 0.00
## COL4A4 0.17 0.20 0.14 0.10 0.17 0.14 0.24
## TCF7 3.59 3.69 2.98 2.07 2.99 2.94 2.83
## OSTM1 13.43 9.37 7.71 38.66 22.34 21.28 12.49
## CDH7 3.68 6.57 3.88 0.91 2.14 2.78 3.42
## IMPG2 0.03 0.03 0.00 0.02 0.01 0.03 0.03
## PCNP 128.97 143.94 116.04 127.36 156.44 164.53 147.05
## EXD2 10.36 10.67 7.30 8.70 10.94 11.45 11.25
## ARG2 17.31 16.79 14.90 24.58 25.07 21.92 31.08
## MEF2C 2.16 1.29 0.67 1.33 1.54 2.07 2.17
## PTPRC 0.00 0.00 0.01 0.01 0.01 0.00 0.00
## CACNA1S 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PKP1 2.05 3.29 1.89 0.50 1.20 1.47 1.57
## UBA5 44.69 45.24 35.03 38.48 47.16 55.86 42.88
## STK17B 2.91 4.23 2.38 6.98 2.82 3.59 3.80
## CDC14B 3.32 2.67 2.04 6.99 5.78 6.50 4.74
## ZNF510 5.16 5.81 4.03 8.51 6.04 7.70 6.61
## LRP2 0.41 0.11 0.51 0.00 0.32 0.05 0.35
## ZNF506 10.68 8.30 7.26 13.45 8.35 11.46 8.57
## JMJD4 16.97 21.42 16.55 9.02 11.79 17.50 8.66
## DUSP12 37.63 45.25 41.24 37.20 37.65 43.05 35.32
## AACS 35.97 45.98 36.86 38.28 38.76 39.51 43.04
## KIAA0141 46.04 49.88 43.25 21.58 39.50 49.28 39.92
## SLC13A1 0.03 0.00 0.01 0.00 0.00 0.00 0.00
## CADPS2 5.63 9.57 7.94 0.98 2.44 3.59 4.85
## PCDHB4 0.19 0.28 0.34 0.16 0.20 0.20 0.30
## PCDHA6 0.53 0.58 0.56 0.56 0.39 0.70 0.55
## PCDHGA2 0.48 0.35 0.20 0.35 0.27 0.36 0.29
## HSPB11 56.73 58.57 55.92 55.64 54.05 49.43 51.59
## PHLPP1 4.70 4.96 3.93 5.20 4.68 4.69 5.71
## ATP8B1 8.86 8.56 5.92 6.85 11.75 11.82 11.65
## IL12RB2 0.07 0.05 0.12 0.07 0.02 0.14 0.02
## SMARCD3 24.74 24.70 23.41 23.73 21.51 23.42 26.78
## WDR70 16.72 28.97 30.90 18.82 19.22 24.43 21.19
## FYB 0.00 0.00 0.00 0.01 0.00 0.00 0.00
## MPP4 0.08 0.04 0.02 0.07 0.03 0.01 0.00
## STRADB 17.21 13.48 14.56 13.20 15.65 16.20 13.99
## BZW1 273.86 220.19 184.49 450.46 329.19 362.84 255.68
## PGR 0.02 0.01 0.00 0.05 0.01 0.03 0.01
## C1QTNF3 1.29 2.41 2.93 0.42 0.74 1.35 1.51
## ME2 27.51 21.40 17.13 37.43 38.06 45.88 28.53
## C5orf22 24.27 25.14 18.56 42.21 30.75 38.29 28.79
## CCNT2 4.87 5.57 4.14 14.82 7.23 7.53 6.71
## FAM135A 5.27 6.57 5.07 10.71 7.70 8.17 5.86
## COL19A1 0.08 0.00 0.03 0.08 0.02 0.03 0.25
## EPB41L3 0.38 0.06 0.20 0.07 0.02 0.00 0.11
## COBLL1 8.10 10.13 6.34 8.92 10.63 11.92 12.47
## DLG3 30.94 31.08 19.76 9.44 18.33 22.97 21.82
## KCNK2 0.16 0.15 0.24 0.00 0.06 0.19 0.14
## SERTAD4 0.23 0.23 0.19 0.13 0.04 0.04 0.02
## TRAF5 3.14 3.16 2.78 0.89 2.21 2.58 2.17
## MRPL22 49.01 46.58 45.84 66.60 58.99 60.06 46.07
## GEMIN5 11.16 12.00 8.78 4.92 11.16 14.07 9.85
## OPRK1 0.01 0.01 0.00 0.01 0.00 0.02 0.00
## NFE2L1 58.60 52.03 36.76 154.88 82.37 77.90 83.82
## SEMA5B 0.03 0.05 0.04 0.15 0.02 0.04 0.04
## GSK3B 29.23 26.49 16.99 41.76 28.64 37.97 30.78
## ITGB5 92.42 74.05 64.09 70.40 113.33 122.10 71.75
## ERC1 6.14 5.94 3.57 5.97 7.12 7.31 7.35
## XPO1 85.86 97.05 73.02 119.78 108.85 102.38 102.41
## C4orf6 0.05 0.14 0.07 0.00 0.00 0.00 0.00
## RNF13 32.33 33.36 27.23 41.44 40.22 39.60 40.95
## TRPM3 0.27 0.00 0.00 0.00 0.00 0.03 0.11
## PALB2 5.27 6.38 6.12 4.27 5.14 4.78 5.67
## DOPEY1 5.61 5.47 4.58 8.93 6.31 7.10 6.32
## LYRM2 51.93 48.22 34.28 54.10 43.39 54.92 40.40
## BCKDHB 13.40 18.36 13.19 6.00 10.75 14.46 17.30
## mRNA_R52 mRNA_R56 mRNA_R55 mRNA_R54 mRNA_R53 mRNA_R51 mRNA_R50
## TSPAN6 17.47 17.69 17.81 11.23 13.34 14.64 13.59
## TNMD 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DPM1 122.39 123.47 121.18 111.65 127.87 116.58 124.17
## SCYL3 9.73 8.77 8.84 12.03 10.22 11.08 11.11
## C1orf112 9.19 10.26 8.29 9.24 11.03 10.10 9.93
## FGR 0.02 0.00 0.02 0.00 0.09 0.04 0.10
## CFH 0.08 0.04 0.03 0.03 0.00 0.04 0.03
## FUCA2 38.77 36.25 36.27 41.70 44.13 43.91 41.28
## GCLC 20.54 20.80 22.25 54.55 33.70 40.17 33.99
## NFYA 10.64 9.02 9.22 6.94 9.51 9.05 9.19
## STPG1 8.21 7.41 7.85 9.62 8.55 8.66 8.74
## NIPAL3 31.65 27.21 28.43 19.40 22.43 26.70 25.21
## LAS1L 21.65 21.26 21.00 17.28 21.38 21.02 22.15
## ENPP4 4.38 4.16 4.01 4.81 4.61 5.63 4.84
## SEMA3F 32.81 37.92 34.68 23.23 29.38 27.52 33.37
## CFTR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ANKIB1 12.26 10.41 9.57 10.61 10.61 11.21 11.95
## CYP51A1 26.36 20.65 21.24 31.71 30.44 31.94 31.26
## KRIT1 20.63 20.43 20.58 20.22 19.00 20.73 22.51
## RAD52 10.22 10.14 9.83 8.09 7.17 9.49 8.04
## BAD 110.64 98.58 97.76 101.46 107.54 99.15 103.05
## LAP3 26.31 23.43 25.23 32.19 32.45 32.19 32.17
## CD99 114.95 107.91 113.88 119.56 126.10 112.28 118.04
## HS3ST1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## AOC1 0.09 0.12 0.06 0.00 0.00 0.01 0.06
## WNT16 0.00 0.00 0.00 0.03 0.00 0.00 0.00
## HECW1 0.00 0.00 0.00 0.00 0.09 0.00 0.07
## MAD1L1 16.63 12.40 12.23 7.58 13.86 9.72 11.47
## LASP1 165.86 149.10 158.28 124.71 133.71 151.49 145.46
## SNX11 19.89 17.48 18.07 27.26 24.60 24.48 25.94
## TMEM176A 0.00 0.00 0.00 0.06 0.00 0.00 0.00
## M6PR 27.57 27.90 24.25 49.37 31.24 43.97 30.69
## KLHL13 4.50 4.07 3.45 1.21 3.22 2.63 3.20
## CYP26B1 0.27 0.28 0.32 0.39 0.47 0.26 0.35
## ICA1 62.98 69.90 60.14 85.15 74.17 66.26 71.41
## DBNDD1 33.62 30.99 32.48 23.08 31.30 25.97 31.81
## ALS2 9.73 7.66 7.95 15.18 12.11 12.78 12.23
## CASP10 0.06 0.04 0.08 0.01 0.01 0.01 0.01
## CFLAR 17.66 16.36 16.82 16.19 17.15 19.03 15.52
## TFPI 0.09 0.08 0.00 0.11 0.06 0.08 0.05
## NDUFAF7 10.72 11.91 10.17 11.54 12.10 10.09 11.96
## RBM5 42.99 47.55 46.73 54.86 40.82 43.81 46.85
## MTMR7 0.39 0.51 0.47 0.81 0.53 0.38 0.48
## SLC7A2 0.04 0.01 0.02 0.03 0.01 0.02 0.03
## ARF5 133.58 140.94 135.72 148.24 147.54 143.20 139.55
## SARM1 0.72 1.87 0.91 2.69 1.47 1.32 1.93
## POLDIP2 137.40 122.86 125.14 148.00 157.67 137.25 155.08
## PLXND1 27.93 31.56 24.37 19.71 22.17 19.44 23.88
## AK2 162.67 148.74 150.09 136.05 160.49 154.12 161.30
## CD38 0.11 0.00 0.02 0.00 0.00 0.00 0.05
## FKBP4 299.74 301.52 286.96 347.11 485.40 311.83 474.20
## KDM1A 37.79 33.11 34.82 29.68 36.36 32.39 36.25
## RBM6 32.68 47.00 40.19 37.46 33.48 35.46 33.44
## CAMKK1 4.09 4.18 4.11 3.91 4.93 5.56 4.53
## RECQL 26.73 21.86 19.57 20.57 27.61 27.60 30.41
## CCDC132 9.93 8.07 8.39 11.76 10.51 11.83 11.80
## HSPB6 0.38 0.43 0.27 0.07 0.23 0.34 0.22
## ARHGAP33 13.10 19.00 14.95 25.47 13.99 19.76 16.77
## NDUFAB1 230.32 201.50 190.34 221.63 252.70 236.29 248.85
## PDK4 1.60 0.88 0.91 0.57 0.73 0.74 0.74
## SLC22A16 0.00 0.00 0.00 0.00 0.00 0.02 0.00
## ZMYND10 23.13 27.64 22.49 8.26 13.90 12.32 13.95
## ABCB5 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## ARX 0.76 0.52 0.62 0.44 0.52 0.53 0.57
## SLC25A13 11.53 9.99 10.17 18.98 16.42 19.42 17.08
## ST7 10.11 10.15 9.58 8.54 10.71 9.98 10.01
## CDC27 52.92 47.89 46.30 43.87 57.60 50.61 54.46
## SLC4A1 0.02 0.02 0.01 0.11 0.00 0.02 0.00
## CALCR 4.20 3.27 3.08 1.48 3.02 2.46 3.98
## HCCS 41.74 36.99 36.46 39.86 46.85 42.89 43.56
## DVL2 19.84 18.61 19.73 52.12 25.44 34.59 27.81
## PRSS22 38.18 40.49 39.21 92.13 47.49 63.56 54.32
## UPF1 26.14 24.78 25.21 23.68 26.08 23.99 26.71
## SKAP2 50.42 31.58 35.21 27.14 34.13 47.66 34.03
## SLC25A5 257.38 231.12 218.24 278.25 311.06 285.18 289.20
## CCDC109B 10.28 11.65 12.78 13.14 16.85 13.02 14.48
## HOXA11 1.24 1.15 1.08 0.40 1.19 0.92 0.91
## POLR2J 89.54 83.79 84.69 77.31 90.71 76.88 82.34
## DHX33 7.30 5.84 6.31 6.51 6.84 7.33 7.74
## MEOX1 0.03 0.00 0.00 0.00 0.00 0.00 0.00
## THSD7A 0.25 0.09 0.14 0.19 0.15 0.17 0.19
## LIG3 26.40 26.69 25.02 28.76 26.46 31.00 28.59
## RPAP3 33.91 33.53 33.12 35.00 34.45 37.91 35.22
## ACSM3 5.04 4.72 3.45 4.45 4.80 4.61 5.18
## AC004381.6 21.54 23.91 23.95 25.24 24.75 28.81 25.85
## CIAPIN1 41.89 40.86 39.23 39.00 49.07 40.31 46.92
## FAM214B 6.56 6.35 7.36 12.66 9.76 10.59 10.31
## COPZ2 29.23 30.47 30.93 15.55 16.08 21.45 17.03
## PRKAR2B 3.39 3.10 2.76 3.38 3.07 3.53 2.84
## MSL3 19.55 22.72 20.05 16.56 17.05 17.23 19.22
## CREBBP 11.29 9.22 10.96 12.87 9.68 12.05 12.95
## BZRAP1 0.92 1.34 0.92 0.45 0.53 0.60 0.45
## MPO 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## PON1 0.26 0.27 0.16 0.55 0.36 0.25 0.34
## GCFC2 16.53 17.17 18.25 20.11 16.59 22.08 19.96
## WDR54 18.15 14.24 16.76 9.39 13.11 14.97 12.24
## CROT 18.27 17.66 17.03 21.83 23.38 22.74 21.44
## ABCB4 0.73 0.84 0.94 0.09 0.14 0.34 0.32
## KMT2E 8.52 8.72 8.92 10.72 8.19 12.61 10.90
## RHBDD2 85.07 84.29 90.51 102.24 90.32 76.42 82.16
## SOX8 0.02 0.01 0.01 0.00 0.00 0.08 0.02
## IBTK 24.63 23.85 24.00 26.91 25.33 28.53 25.78
## ZNF195 8.43 10.24 9.29 11.61 9.28 9.59 9.80
## MYCBP2 7.45 6.50 6.37 7.92 7.67 7.57 8.27
## FBXL3 17.95 15.76 15.02 16.53 19.21 17.79 19.07
## ITGAL 2.67 2.31 1.79 0.80 1.50 1.17 1.26
## PDK2 44.90 44.38 43.20 43.51 40.56 47.80 42.44
## ITGA3 25.74 25.50 27.32 26.75 23.80 26.46 24.12
## ZFX 5.01 4.46 4.56 5.89 4.72 5.65 5.12
## LAMP2 70.75 61.93 62.22 97.06 91.06 105.87 98.19
## GGNBP2 74.55 81.39 78.28 99.64 86.94 88.11 91.07
## ITGA2B 4.78 6.78 4.48 4.86 4.53 2.97 4.97
## ASB4 0.17 0.32 0.07 0.23 0.00 0.09 0.11
## GDE1 54.03 51.28 48.76 48.64 54.59 48.54 61.24
## C19orf60 27.65 28.55 30.42 33.67 30.27 35.44 32.21
## CRLF1 34.64 35.86 35.20 30.50 34.37 32.94 35.12
## OSBPL7 20.01 21.58 18.91 12.70 10.88 17.12 15.31
## TMEM98 11.81 9.60 10.79 9.50 9.95 11.22 11.01
## YBX2 49.76 62.05 54.64 64.70 54.63 49.62 56.81
## KRT33A 0.64 0.39 0.51 0.13 0.32 0.21 0.27
## ABCC8 0.29 0.67 0.34 0.23 0.42 0.27 0.29
## CCL18 0.06 0.06 0.04 0.05 0.00 0.11 0.05
## CCL3 0.05 0.00 0.11 0.00 0.04 0.00 0.00
## SYNRG 13.42 11.65 11.32 13.75 13.51 15.78 14.40
## CACNG3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMEM132A 260.32 338.30 307.43 172.25 191.26 178.95 195.08
## AP2B1 135.63 105.86 111.21 125.52 142.79 152.06 154.00
## TAC1 0.00 0.00 0.00 0.00 0.00 0.00 0.05
## ZNF263 29.19 26.05 26.36 44.22 30.84 33.25 34.08
## CX3CL1 0.08 0.04 0.03 0.01 0.01 0.00 0.02
## SPATA20 68.95 69.66 70.23 106.10 60.15 93.78 64.92
## CACNA1G 0.02 0.07 0.05 0.06 0.04 0.03 0.04
## TNFRSF12A 83.22 69.28 73.35 123.83 134.09 116.74 112.18
## DLX6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MAP3K9 4.89 4.58 4.45 7.51 5.93 7.65 7.22
## RALA 44.73 39.81 36.34 44.27 47.57 43.72 46.83
## BAIAP2L1 28.28 25.81 25.81 29.62 27.77 31.10 27.67
## KDM7A 7.79 6.63 6.82 8.69 7.22 8.23 7.51
## ETV1 1.13 2.15 1.78 1.01 1.53 1.66 1.87
## AGK 14.67 16.01 14.90 13.73 12.49 14.74 14.93
## ALDH3B1 22.92 22.26 23.63 25.28 18.10 29.55 20.01
## TTC22 0.23 0.16 0.15 0.06 0.10 0.15 0.17
## PHTF2 30.08 25.20 25.67 30.24 33.37 32.65 33.97
## CCL26 0.09 0.00 0.13 0.30 0.00 0.00 0.07
## FARP2 5.04 4.68 4.52 7.11 6.61 5.81 6.84
## USH1C 1.10 0.73 0.52 0.30 0.59 0.51 0.08
## GGCT 231.74 281.87 264.48 567.25 381.82 479.11 404.48
## DBF4 22.42 21.83 21.50 26.41 27.84 27.46 28.14
## TBXA2R 0.67 0.63 0.56 0.35 0.41 0.54 0.40
## IFRD1 17.95 16.56 16.95 43.37 27.61 35.38 27.27
## LGALS14 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## COX10 8.85 6.24 6.29 10.43 8.23 10.75 9.59
## GTF2IRD1 24.17 25.93 27.19 39.87 29.21 31.69 30.25
## PAF1 44.87 42.47 40.83 32.29 42.38 31.08 39.45
## VPS41 47.28 34.12 40.47 66.23 47.63 77.66 60.31
## ARHGAP44 1.56 1.24 1.75 1.37 1.07 1.33 1.33
## ELAC2 31.91 30.54 27.88 30.83 30.50 27.88 30.93
## SCIN 1.14 1.12 1.08 2.06 1.04 2.21 1.01
## ARSD 29.74 28.21 30.23 24.64 27.14 29.49 29.06
## PNPLA4 25.16 19.12 22.21 20.60 21.77 22.87 21.96
## MYH13 0.01 0.00 0.00 0.00 0.00 0.00 0.00
## ADIPOR2 34.65 29.58 27.99 32.12 35.06 34.44 36.13
## CDKL3 4.89 3.88 3.06 8.83 4.94 5.53 5.82
## UPP2 0.00 0.00 0.01 0.00 0.01 0.00 0.01
## PRSS21 0.12 0.13 0.12 0.00 0.04 0.17 0.05
## MARK4 7.05 6.91 7.48 6.15 8.07 7.21 7.35
## PROM1 0.34 0.15 0.23 0.16 0.10 0.40 0.27
## CCDC124 70.81 67.59 69.87 64.54 71.50 58.03 66.54
## CEACAM21 0.42 0.42 0.53 0.34 0.39 0.51 0.39
## PAFAH1B1 57.78 44.25 46.74 55.70 64.13 58.77 61.81
## NOS2 0.02 0.00 0.01 0.00 0.01 0.00 0.01
## DNAH9 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## KIAA0100 60.28 53.63 54.65 69.28 59.39 59.23 66.95
## SLC13A2 0.04 0.03 0.02 0.00 0.00 0.00 0.00
## GAS7 0.73 0.64 0.92 0.19 0.40 0.41 0.39
## TRAPPC6A 57.93 56.97 53.92 57.87 53.61 60.80 55.77
## MATK 0.00 0.00 0.06 0.08 0.03 0.15 0.08
## CEACAM7 0.08 0.04 0.00 0.00 0.00 0.01 0.05
## CD79B 0.15 0.00 0.00 0.00 0.00 0.00 0.00
## SCN4A 0.08 0.01 0.08 0.03 0.07 0.09 0.02
## ST7L 11.85 13.70 11.95 8.59 10.25 12.90 10.17
## TKTL1 0.00 0.00 0.00 0.00 0.10 0.07 0.00
## PAX6 6.24 4.68 6.45 4.23 4.64 5.53 4.82
## RPUSD1 19.56 16.51 19.39 21.65 21.37 17.62 21.38
## RHBDF1 60.01 73.25 68.51 99.83 67.73 69.61 66.90
## LUC7L 31.84 38.15 30.95 30.64 29.43 21.32 29.32
## CACNA2D2 2.36 2.41 2.50 1.10 1.41 0.98 1.44
## BAIAP3 15.84 17.54 17.20 31.08 16.26 23.41 17.24
## TSR3 48.89 44.73 48.34 46.36 46.49 47.60 45.84
## PIGQ 34.31 38.01 36.80 32.58 33.07 32.48 33.78
## CRAMP1L 7.43 8.14 7.62 13.11 8.86 12.35 10.26
## TEAD3 25.92 27.81 26.40 27.77 25.91 22.14 25.89
## SELE 0.05 0.02 0.03 0.00 0.00 0.01 0.01
## DNAJC11 21.16 20.81 20.39 26.62 24.83 24.63 25.62
## FMO3 0.09 0.19 0.13 0.07 0.06 0.09 0.11
## MYLIP 8.13 9.05 8.49 8.78 8.02 9.42 8.74
## NOX1 0.10 0.00 0.05 0.02 0.00 0.01 0.04
## E2F2 2.75 2.69 2.55 2.04 2.91 2.11 2.87
## PSMB1 236.02 242.25 235.10 254.95 281.81 237.31 264.10
## SYN1 2.75 2.02 1.96 0.79 2.05 1.31 2.04
## JARID2 7.70 8.60 8.53 7.05 6.98 8.31 7.28
## CDKL5 0.28 0.16 0.22 0.33 0.34 0.28 0.30
## CAMK1G 0.01 0.00 0.00 0.00 0.01 0.00 0.00
## CDK11A 26.91 31.10 24.00 47.80 31.22 31.82 38.25
## NADK 34.08 37.02 34.86 60.49 41.05 41.43 41.48
## TFAP2B 0.08 0.17 0.08 0.05 0.03 0.10 0.16
## TFAP2D 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DLEC1 0.10 0.10 0.12 0.12 0.23 0.25 0.06
## CYTH3 2.96 1.97 2.36 8.68 5.11 5.84 4.79
## ADAM22 1.49 1.01 1.19 1.32 0.83 1.08 1.11
## SYPL1 79.78 68.24 66.42 64.77 76.05 78.21 76.01
## CYB561 152.06 161.55 156.34 115.13 134.77 127.22 141.85
## SPAG9 33.81 29.47 29.64 59.33 47.07 54.57 50.47
## CELSR3 16.43 17.70 14.99 17.55 15.54 15.84 16.10
## AASS 1.10 0.93 1.21 0.71 0.61 0.91 0.74
## PLEKHG6 4.61 4.37 4.14 6.27 5.77 4.97 4.35
## SS18L2 49.35 53.04 54.04 60.60 62.46 52.22 58.39
## MPND 10.65 10.73 11.93 8.86 9.54 10.33 8.73
## MGST1 406.23 467.65 428.89 527.14 549.36 560.87 514.71
## CRY1 13.36 12.45 10.54 13.18 16.28 15.09 13.94
## PGLYRP1 0.12 0.11 0.08 0.05 0.10 0.05 0.08
## NFIX 13.71 10.80 10.79 5.53 8.01 9.33 9.52
## ST3GAL1 14.52 13.58 16.54 17.29 10.28 17.43 12.55
## MMP25 2.86 3.31 3.28 1.75 2.14 2.10 2.19
## IL32 6.40 4.98 6.00 2.75 5.88 5.24 4.18
## PKD1 22.79 26.65 29.41 59.29 29.50 40.02 34.72
## MAPK8IP2 2.16 1.00 1.66 13.90 6.92 8.80 7.78
## MED24 67.85 72.50 62.44 68.35 56.91 62.46 62.05
## RHOBTB2 3.84 3.53 3.94 4.24 4.41 3.59 4.06
## HEATR5B 7.72 6.38 6.65 7.97 7.17 8.10 8.71
## SEC62 298.11 297.53 282.19 214.34 258.68 244.31 270.03
## RPS20 2456.01 2396.99 2418.44 1999.38 2341.85 2354.93 2269.54
## CSDE1 130.76 106.12 112.59 109.49 125.20 134.83 132.61
## UBE3C 22.53 15.72 18.31 19.83 21.29 24.25 22.55
## REV3L 8.06 6.73 6.91 9.93 8.41 7.14 7.72
## TENM1 0.10 0.12 0.14 0.04 0.03 0.03 0.07
## PAX7 0.02 0.04 0.00 0.00 0.00 0.00 0.00
## MASP2 0.29 0.53 0.41 0.57 0.23 0.42 0.35
## IYD 0.62 0.45 0.52 0.10 0.11 0.57 0.47
## FAM76A 6.40 5.38 6.54 10.21 7.52 9.26 9.35
## TRAF3IP3 3.31 2.88 3.31 3.40 2.81 2.69 3.16
## POMT2 13.20 14.85 13.21 16.74 17.13 14.19 17.78
## VTA1 37.56 30.93 31.40 32.16 39.08 34.24 38.72
## MLXIPL 18.82 25.16 21.35 25.37 18.18 19.84 21.90
## BAZ1B 32.93 26.34 26.33 32.87 32.47 34.34 36.25
## RANBP9 38.82 38.81 37.49 52.55 44.38 51.52 47.89
## ETV7 2.28 2.62 3.12 0.60 1.58 1.41 1.35
## SPRTN 14.44 14.90 12.75 13.71 18.57 15.98 17.46
## METTL13 36.47 31.86 32.79 39.90 39.19 39.56 39.06
## DYRK4 16.60 18.57 16.40 3.77 8.39 9.17 8.97
## ZNF207 146.58 132.28 136.63 106.23 131.99 120.98 126.99
## UQCRC1 167.96 173.46 178.66 194.33 162.53 179.73 172.33
## STARD3NL 35.89 30.12 29.86 34.20 36.25 35.91 38.03
## CD9 106.70 110.90 99.33 73.70 102.12 97.26 102.89
## HHATL 0.00 0.00 0.00 0.00 0.06 0.03 0.00
## NCAPD2 10.62 11.26 10.44 10.16 11.02 10.38 12.75
## IFFO1 0.06 0.19 0.07 0.05 0.07 0.00 0.12
## GIPR 12.82 15.00 14.66 17.88 10.92 15.29 13.87
## PHF7 13.34 17.76 14.43 16.50 16.38 24.20 20.19
## SEMA3G 4.59 3.79 4.61 3.26 4.95 4.31 4.81
## NISCH 26.46 26.49 28.28 43.10 26.00 34.85 29.70
## STAB1 0.22 0.42 0.55 0.24 0.12 0.05 0.13
## FUZ 9.87 10.43 10.38 5.40 5.40 7.29 6.08
## SLC6A13 0.09 0.09 0.12 0.10 0.09 0.11 0.05
## IDS 19.22 16.35 17.71 23.32 21.65 28.40 24.30
## PRSS3 0.00 0.00 0.03 0.00 0.04 0.00 0.00
## ZNF200 9.27 8.74 8.04 8.84 8.99 7.66 9.85
## CD4 0.47 0.26 0.39 0.15 0.26 0.11 0.13
## LRRC23 10.41 6.73 8.54 5.31 6.03 6.82 6.93
## BTK 0.00 0.00 0.08 0.00 0.00 0.04 0.00
## HFE 33.87 27.89 26.50 24.13 26.70 30.26 34.20
## SCMH1 20.32 23.21 22.51 14.01 15.70 16.23 17.62
## FYN 1.51 1.19 1.17 0.56 0.56 1.21 0.74
## HIVEP2 1.52 1.28 1.21 1.25 1.26 1.28 1.35
## FMO1 0.05 0.05 0.07 0.00 0.06 0.00 0.02
## TCEB3 17.31 14.10 15.93 16.28 17.01 16.76 18.59
## LYPLA2 48.50 48.53 43.89 46.14 47.72 41.29 47.60
## CLCN6 4.34 4.60 4.71 7.47 4.93 6.86 5.06
## MRC2 1.18 0.88 0.99 0.62 0.69 0.71 0.73
## NME2 387.08 390.55 332.04 405.20 456.05 489.13 411.76
## SLC6A7 0.00 0.02 0.00 0.00 0.00 0.00 0.00
## TSPAN9 23.22 23.98 25.35 16.18 18.13 18.54 21.16
## BTBD7 11.73 10.31 10.24 13.31 12.72 13.48 13.37
## APBA3 6.58 7.54 6.93 10.93 7.76 8.48 7.70
## MKS1 36.79 39.75 37.02 31.35 30.92 33.50 32.20
## ABHD5 23.47 21.96 21.32 27.93 27.68 26.19 27.13
## KAL1 0.00 0.00 0.05 0.00 0.01 0.00 0.00
## AKAP8L 45.68 52.90 46.05 60.74 57.11 55.20 62.11
## MBTD1 11.27 10.47 10.32 13.13 11.61 11.96 11.94
## UTP18 62.62 54.55 51.04 68.30 78.99 70.39 74.58
## RNF216 13.32 11.82 12.30 14.95 14.80 15.30 16.11
## TTC19 31.60 28.25 29.27 22.78 27.67 29.75 27.82
## PTBP1 123.64 128.34 130.49 139.66 141.08 124.94 145.95
## DPF1 2.17 2.32 2.67 1.83 2.59 2.26 1.85
## SYT7 43.91 41.03 41.29 20.64 23.73 30.04 27.36
## LARS2 10.30 9.84 9.67 10.38 10.19 11.23 11.16
## PIK3C2A 8.37 7.15 7.27 10.80 8.13 11.45 9.04
## PLAUR 1.63 1.63 1.64 0.89 1.71 1.40 1.33
## ANLN 67.39 81.52 65.23 61.38 79.82 63.22 76.30
## WIZ 15.51 12.84 14.12 14.91 14.54 14.75 15.29
## RABGAP1 47.87 43.76 39.99 45.14 42.87 41.59 47.04
## DCN 0.00 0.42 0.01 0.38 0.00 0.05 0.06
## QPCTL 8.07 8.99 9.02 6.97 8.00 6.71 7.71
## PPP5C 49.24 53.77 51.93 51.46 46.58 43.54 49.47
## CEP68 2.28 1.70 1.99 2.63 2.29 2.95 2.58
## MAP4K3 11.94 11.63 10.52 12.76 12.58 12.43 12.93
## ZBTB32 0.75 0.52 0.77 0.54 0.53 0.50 0.14
## TYROBP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMEM159 65.72 57.03 57.45 53.05 59.56 61.57 64.03
## GABRA3 0.08 0.16 0.49 0.02 0.04 0.16 0.05
## BRCA1 17.32 19.07 15.53 19.25 21.42 20.01 20.71
## ERCC1 60.31 62.84 58.95 45.18 45.28 47.15 52.17
## CD22 0.80 0.50 0.67 1.78 0.78 1.83 1.08
## MBTPS2 22.31 16.81 18.14 16.63 20.18 22.31 21.78
## PRICKLE3 12.61 12.87 13.33 19.67 13.56 16.39 13.70
## LTF 0.08 0.02 0.08 0.00 0.01 0.03 0.06
## EXTL3 4.96 4.10 4.34 4.96 5.29 4.91 5.00
## NR1H4 0.00 0.00 0.00 0.00 0.02 0.00 0.04
## ELOVL5 80.20 71.18 67.80 81.68 83.82 81.86 86.30
## ALOX5 0.11 0.13 0.09 0.06 0.33 0.30 0.08
## KDM5D 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CALCOCO1 56.69 54.64 50.74 49.90 43.09 52.55 49.71
## UBR7 43.82 41.39 39.83 40.43 48.04 41.13 47.00
## MAP4K5 18.81 20.04 18.79 19.68 18.82 22.76 22.02
## EHD3 0.70 0.51 0.58 0.14 0.14 0.30 0.28
## PSMC4 89.11 88.78 85.51 94.88 99.50 87.54 91.65
## MAN2B2 30.88 29.73 30.69 26.96 27.83 27.33 31.09
## SLC7A14 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## CLDN11 0.23 0.07 0.15 0.08 0.02 0.06 0.10
## SLC25A39 197.44 201.96 202.13 280.22 243.01 231.69 238.40
## MVP 11.01 10.93 12.46 12.46 11.74 11.27 11.98
## NUB1 44.38 36.31 36.54 28.93 37.78 36.97 42.52
## PGM3 27.19 27.99 29.09 23.80 27.58 33.03 30.93
## RWDD2A 8.72 7.16 8.83 10.79 10.81 10.41 11.04
## CLK1 25.41 24.90 28.18 36.41 27.35 26.83 28.47
## POLR3B 8.31 6.87 8.17 6.25 8.45 7.82 8.55
## ANGEL1 20.78 17.15 17.23 22.20 21.82 24.22 23.41
## RNF14 69.11 54.40 57.95 96.28 85.70 102.82 85.16
## DNASE1L1 13.63 13.48 12.95 19.10 14.46 15.64 13.49
## DDX11 18.07 24.02 23.31 26.07 23.62 21.63 26.47
## HEBP1 18.07 18.02 17.29 18.45 19.83 20.86 19.24
## GPRC5A 3.89 2.82 2.95 1.25 2.39 2.34 2.35
## MAMLD1 0.17 0.12 0.08 0.10 0.11 0.09 0.18
## CD6 0.28 0.42 0.31 0.06 0.23 0.14 0.15
## TACC3 46.36 57.36 50.28 53.83 57.18 44.89 51.65
## UFL1 32.47 30.93 31.45 28.53 27.13 30.55 29.85
## POLA2 31.40 40.21 33.97 34.58 36.37 36.61 39.11
## ZC3H3 19.69 19.31 20.45 19.13 19.23 17.88 19.25
## CAPN1 101.70 95.72 96.42 114.86 103.00 105.03 110.68
## ACPP 0.43 0.30 0.27 0.10 0.30 0.24 0.26
## MDH1 169.24 167.62 159.09 187.57 203.68 198.25 198.66
## SLC30A9 45.49 41.90 41.26 42.15 47.43 45.55 47.07
## MTMR11 13.15 17.39 16.42 25.21 19.01 19.97 18.70
## COX15 68.11 58.19 60.43 56.91 56.93 63.87 59.79
## CCDC88C 9.21 10.12 10.89 10.26 10.15 9.96 11.23
## YAF2 8.88 7.71 9.60 11.56 10.41 11.07 10.90
## ZMYND11 56.38 55.19 52.65 58.06 59.66 56.91 61.57
## WAS 0.32 0.30 0.52 0.72 0.38 0.25 0.45
## DPEP1 0.00 0.00 0.05 0.00 0.00 0.00 0.00
## BID 40.78 45.01 41.79 30.80 40.49 30.61 37.36
## MATR3 186.58 176.58 182.72 159.23 195.64 207.31 204.21
## NPC1L1 0.04 0.05 0.03 0.03 0.01 0.01 0.03
## XYLT2 48.20 48.41 47.98 61.29 52.73 57.12 54.19
## RGPD5 1.61 0.59 0.44 0.23 0.22 0.35 0.63
## STMN4 0.47 0.40 0.30 0.11 0.10 0.08 0.17
## NUDCD3 39.52 38.14 35.12 42.65 38.86 44.55 39.46
## ISL1 0.00 0.00 0.00 0.00 0.00 0.04 0.00
## CHDH 8.42 8.44 8.24 9.84 9.41 10.76 10.68
## IL20RA 21.85 22.34 22.83 14.83 18.12 20.56 18.05
## CLCA1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CLCA4 0.00 0.00 0.07 0.00 0.00 0.00 0.00
## GLT8D1 85.68 86.70 78.80 71.71 75.57 72.80 78.18
## ATP2C1 45.49 39.64 36.80 47.70 45.23 43.81 47.74
## SRCIN1 8.76 8.32 7.57 6.77 5.37 6.84 6.79
## IGF1 0.00 0.00 0.01 0.07 0.00 0.00 0.00
## SLC38A5 0.20 0.43 0.31 0.28 0.12 0.14 0.32
## MAGIX 5.97 6.38 6.11 10.79 8.43 10.67 7.56
## RALBP1 18.33 16.83 16.82 20.37 19.62 19.96 19.68
## RUFY3 11.72 15.05 12.27 15.28 12.87 13.29 14.71
## CNTN1 0.02 0.01 0.00 0.05 0.00 0.00 0.01
## SLC11A1 0.16 0.22 0.23 0.25 0.17 0.09 0.08
## WWTR1 25.09 18.12 17.91 17.83 18.61 27.00 22.26
## AGPS 0.00 0.00 0.00 0.01 0.01 0.00 0.01
## CXorf56 15.42 13.17 15.51 18.85 18.55 20.29 17.01
## ATP1A2 0.07 0.01 0.02 0.03 0.02 0.05 0.03
## TTC27 13.77 9.69 10.21 9.02 13.07 10.76 11.67
## ZNF582 3.23 3.17 1.59 2.75 2.61 2.62 2.58
## VSIG2 0.14 0.03 0.13 0.17 0.22 0.09 0.10
## PHLDB1 25.13 23.38 23.73 24.06 24.38 24.30 25.44
## MARCO 0.02 0.02 0.00 0.00 0.00 0.05 0.03
## CYP24A1 0.03 0.00 0.02 0.00 0.24 0.00 0.00
## PRDM11 3.55 2.90 2.82 2.87 3.37 3.77 3.63
## SYT13 0.53 0.16 0.17 0.27 0.25 0.28 0.22
## SNAI2 0.02 0.00 0.01 0.03 0.01 0.00 0.01
## CD74 53.90 58.58 55.54 40.71 42.53 50.95 41.10
## HGF 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZRANB1 7.62 7.36 6.89 8.71 8.26 7.50 8.25
## NCDN 12.57 12.39 12.81 10.81 12.45 10.64 13.07
## GPR124 0.15 0.12 0.18 0.13 0.08 0.16 0.09
## ZFP64 12.89 10.24 10.17 13.01 12.96 12.80 12.56
## MNAT1 67.29 72.98 66.53 69.13 78.14 72.84 79.44
## SAMD4A 12.04 10.14 10.32 12.25 8.71 14.28 10.37
## RUNX3 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## MRE11A 27.67 22.60 23.37 22.35 23.70 25.65 26.71
## PLEKHB1 4.70 3.87 6.43 2.57 3.38 5.30 4.67
## SERPINB1 9.84 10.81 10.12 7.53 7.63 8.03 7.07
## CYP3A43 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SLC7A9 0.09 0.07 0.22 0.17 0.06 0.17 0.10
## SPAST 5.11 3.90 4.14 5.19 5.27 5.09 5.18
## NRXN3 0.02 0.00 0.01 0.00 0.00 0.01 0.00
## OSBPL5 14.68 12.61 12.77 10.41 9.83 10.27 10.19
## AQR 27.10 29.40 28.54 29.12 28.82 24.98 26.88
## CPS1 0.09 0.07 0.08 0.02 0.01 0.02 0.05
## C8B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## FHL1 0.00 0.10 0.00 0.00 0.01 0.00 0.00
## RTFDC1 147.27 144.99 148.34 133.03 144.17 138.23 142.44
## GABRA1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NLRP2 42.68 42.21 41.61 37.21 44.37 41.05 47.06
## SLC45A4 2.71 1.78 2.13 3.76 2.86 3.28 3.44
## RNF10 155.87 168.89 165.77 208.31 176.42 178.30 181.96
## ZNF839 25.59 27.35 28.35 27.89 22.49 26.00 22.81
## ZDHHC6 18.18 19.42 18.92 18.83 20.11 18.86 17.76
## GRAMD1B 0.42 0.17 0.28 0.34 0.33 0.22 0.25
## RNH1 81.04 80.12 81.07 95.89 87.11 86.30 89.16
## NDUFS1 66.66 60.54 58.88 59.54 65.96 69.32 69.45
## RB1CC1 20.72 16.86 15.64 24.18 20.70 21.67 22.87
## ERP44 18.10 17.32 18.10 25.55 21.26 23.58 21.98
## ALAS1 31.17 30.70 29.57 22.32 28.94 24.32 27.78
## BIRC3 1.51 1.89 2.10 0.48 0.80 1.07 0.82
## AKAP11 7.93 6.11 6.52 8.54 7.16 8.83 8.10
## GLRX2 34.44 34.92 31.79 42.46 48.42 40.20 45.89
## SNAPC1 10.85 8.93 10.90 16.07 12.85 14.02 12.94
## DERA 135.73 128.77 125.02 60.54 89.90 116.89 79.31
## STRAP 187.39 168.07 175.76 173.63 203.73 185.96 189.74
## ABCC2 0.27 0.42 0.22 0.32 0.30 0.32 0.39
## DEF6 27.91 32.33 31.63 28.42 22.82 26.18 25.72
## PLEKHO1 2.22 3.07 2.64 1.08 2.56 1.09 1.86
## GCLM 6.91 5.89 7.37 40.45 23.63 26.65 23.93
## UBR2 9.99 9.00 9.08 8.66 8.97 9.48 9.53
## EHD2 27.16 24.39 25.66 13.99 19.26 16.31 17.88
## DEPDC1 12.20 12.61 10.91 11.44 14.69 14.53 15.75
## CCDC28A 7.11 6.56 6.73 6.08 6.12 6.38 6.15
## RRAGD 4.94 2.39 4.59 31.47 12.36 28.23 12.83
## HSF2 8.10 8.83 8.38 10.67 10.53 9.58 9.59
## PHF20 22.43 17.56 17.98 21.15 20.24 23.42 22.38
## HSD17B6 0.52 0.56 0.66 0.54 0.63 0.41 0.44
## NR1H3 27.68 28.55 28.44 21.13 22.90 24.58 23.11
## TYMP 4.25 3.64 4.89 2.74 2.75 3.31 2.81
## NCAPH2 29.91 30.76 29.46 39.77 33.04 29.89 33.39
## TOMM34 39.69 39.39 38.02 53.94 42.21 52.06 43.40
## SEC63 49.07 60.03 57.37 53.20 56.45 58.73 54.79
## KPNA6 11.67 10.56 10.23 10.97 11.47 11.70 12.02
## VIM 1.98 1.36 1.90 0.91 1.47 1.86 1.50
## RTEL1-TNFRSF6B 4.99 7.62 6.09 6.56 5.50 5.23 5.03
## FAS 13.45 14.03 12.32 12.57 15.55 17.77 15.89
## RNASET2 22.86 26.01 25.59 24.41 23.33 26.50 24.43
## CD44 32.58 32.09 32.67 22.35 30.27 28.59 27.56
## KCNG1 1.45 0.90 0.83 0.65 1.17 0.95 0.76
## AGPAT4 0.55 1.02 0.98 0.28 0.64 0.40 0.52
## SLAMF7 0.06 0.00 0.00 0.16 0.05 0.18 0.00
## BTN3A1 6.16 8.50 7.55 3.11 3.08 5.36 3.45
## MIPEP 15.16 20.07 16.66 17.43 16.26 19.04 16.22
## PRKCH 13.58 12.40 11.91 17.76 14.72 17.36 15.04
## INSRR 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## IFNGR1 12.95 10.82 11.49 11.43 13.33 13.44 13.36
## B4GALT7 18.27 18.58 20.62 21.89 19.94 22.30 20.46
## SH2D2A 0.91 1.05 1.55 0.77 0.39 0.96 0.58
## VRK2 12.29 10.45 10.03 13.57 13.80 13.69 14.17
## TNFRSF1B 0.19 0.25 0.25 0.14 0.15 0.11 0.08
## VEZT 56.78 46.61 47.85 50.88 51.85 56.22 54.86
## POU2F2 0.15 0.03 0.06 0.02 0.05 0.01 0.10
## BRD9 30.94 33.79 34.07 57.48 39.72 41.04 41.17
## SNX1 62.24 59.54 56.50 47.30 59.17 57.93 58.97
## TBPL1 10.77 7.56 8.21 9.93 9.89 9.47 11.13
## ARNTL2 0.33 0.20 0.41 0.10 0.52 0.37 0.40
## BCLAF1 69.22 61.10 63.81 51.30 60.55 68.21 66.00
## SLC39A9 86.72 76.76 77.96 73.57 80.30 80.71 83.83
## ANK1 3.11 1.84 1.58 0.70 0.94 1.49 1.01
## IBSP 0.08 0.04 0.03 0.03 0.13 0.03 0.03
## TFB1M 12.43 12.26 12.76 8.95 10.23 8.95 10.69
## RABEP1 78.51 76.70 72.34 76.28 69.77 73.35 81.48
## HMGB3 84.21 88.13 83.92 48.31 81.26 65.49 76.57
## NUP160 26.03 24.85 24.69 27.60 28.89 29.08 31.96
## BAK1 23.13 19.00 21.59 24.73 25.88 22.39 24.07
## MUSK 0.00 0.14 0.03 0.00 0.03 0.00 0.01
## IKZF2 3.16 3.24 3.30 2.03 2.02 3.18 2.99
## GRN 337.03 297.95 313.85 532.27 361.29 478.62 399.45
## FAM13B 10.27 9.04 8.54 11.32 10.59 11.42 11.67
## ARHGAP31 0.80 0.64 0.63 0.50 0.59 0.79 0.69
## CENPQ 9.61 8.65 8.66 7.81 9.77 8.87 9.38
## SARS 92.32 73.11 76.83 107.39 106.27 119.63 108.18
## RANBP3 24.41 32.70 27.36 29.44 26.95 21.16 25.77
## ARID4A 12.81 11.54 12.01 15.26 11.12 14.41 12.93
## TSSC1 22.14 22.24 23.33 21.44 19.65 21.82 20.99
## PNPLA6 13.29 12.31 12.01 16.26 13.21 12.79 11.89
## IFT88 13.04 14.15 11.84 9.50 13.51 13.12 12.73
## ALG1 27.99 25.18 24.81 27.64 26.73 27.59 28.13
## ZCCHC8 26.09 30.12 26.73 48.94 30.58 33.64 32.63
## ABCF2 19.71 15.11 16.51 16.86 22.09 19.55 22.00
## CHPF2 9.54 9.03 9.79 12.70 10.60 9.35 11.90
## LRRC7 0.05 0.11 0.00 0.00 0.05 0.03 0.03
## FUT8 5.77 5.59 4.31 4.06 4.54 4.01 4.60
## UBA6 12.37 9.29 8.11 7.99 9.61 8.63 10.10
## GAB2 12.25 9.70 11.14 16.21 14.30 24.11 17.38
## ATP6V0A1 52.17 52.82 53.51 72.81 56.07 65.61 63.16
## PIAS1 13.05 11.06 11.29 11.60 12.01 12.59 11.92
## SLC4A7 15.51 14.46 13.85 13.02 14.96 14.83 17.13
## APBA2 0.00 0.00 0.00 0.00 0.02 0.00 0.00
## MAP2K3 18.15 17.17 20.03 20.54 19.32 19.75 19.04
## EFCAB1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMSB10 946.87 844.85 858.35 734.77 951.98 874.54 862.41
## ASTE1 7.38 5.85 6.69 7.11 6.33 7.05 6.46
## RNF19A 15.67 16.74 17.58 15.52 13.63 15.34 16.58
## PEX3 14.73 15.30 15.63 17.55 16.75 18.01 16.65
## GABARAPL2 169.41 159.89 146.21 124.41 163.68 145.88 166.53
## MYOC 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## SH3YL1 70.71 76.41 71.24 107.25 76.40 81.89 83.29
## FAM136A 31.18 30.59 29.18 27.68 30.63 28.60 29.21
## VCL 35.07 30.36 29.99 33.39 36.91 37.13 41.13
## DEPDC1B 12.73 15.36 12.69 9.97 14.72 10.98 12.79
## DAPK2 5.51 4.89 4.77 4.72 5.09 5.48 5.24
## NSMAF 19.97 20.73 20.46 22.73 20.63 24.15 20.60
## ADSS 31.52 28.08 28.56 30.27 32.19 35.80 34.15
## STAP1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TIMP2 115.30 119.24 109.00 113.10 114.05 114.69 114.53
## RFC1 26.22 22.97 23.19 25.26 26.62 23.35 28.02
## TBC1D23 19.27 18.42 17.71 16.98 17.76 18.10 18.15
## CUL3 54.30 57.21 51.74 57.35 66.37 52.83 61.89
## MYOM2 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## OTC 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CYP46A1 0.44 0.47 0.49 0.48 0.27 0.39 0.39
## ZZZ3 14.44 11.62 13.08 17.94 15.18 16.97 15.72
## SLC18A1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## USP2 3.12 2.64 2.80 2.04 3.45 3.62 3.02
## CASR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TUBG2 43.79 47.65 44.98 40.70 42.59 38.00 43.08
## RPL26L1 75.28 75.77 70.76 70.42 81.96 69.17 77.97
## FLT4 13.87 14.97 12.00 9.63 13.00 9.20 14.26
## NSUN2 54.74 47.66 46.14 53.12 60.33 51.02 62.85
## FBXO42 9.21 8.72 9.03 12.79 10.45 8.41 10.29
## MFAP3 25.74 19.55 19.37 20.91 23.69 25.68 26.23
## MRI1 18.64 20.68 21.16 19.84 19.63 19.44 20.74
## METTL1 43.52 39.07 42.89 35.30 46.50 40.25 44.41
## HOXC8 0.76 1.42 1.45 0.51 0.50 0.68 0.49
## AGA 26.31 20.36 21.35 21.44 31.59 29.15 26.67
## PI4K2B 19.19 17.01 16.72 19.27 20.12 21.65 18.85
## BOD1L1 11.53 12.84 12.73 11.99 8.83 10.03 10.38
## MAT2B 53.48 47.64 47.00 51.72 53.73 56.58 55.21
## TLL1 0.08 0.01 0.01 0.00 0.07 0.07 0.05
## EDC4 39.68 41.17 39.98 57.73 50.73 43.19 49.86
## TRIO 8.73 9.26 7.42 11.92 9.09 8.58 10.21
## VCAN 0.40 0.29 0.49 0.14 0.29 0.29 0.46
## CLEC16A 9.30 9.31 8.18 9.10 9.42 8.55 10.19
## MSR1 0.15 0.28 0.13 0.26 0.24 0.41 0.21
## CDH1 416.45 432.64 441.05 440.29 404.40 394.54 436.79
## SKIV2L2 52.34 45.69 47.22 47.87 50.89 48.07 53.50
## DNAH5 2.72 3.26 4.46 2.00 2.06 2.27 2.10
## ZFYVE16 15.13 18.98 17.97 20.43 17.91 17.89 18.85
## FAM65A 23.92 21.08 22.43 28.88 21.86 28.04 24.30
## C6 0.00 0.00 0.01 0.00 0.01 0.00 0.00
## RAI14 7.45 5.11 4.55 15.12 9.08 11.71 10.17
## SOX30 0.02 0.06 0.04 0.08 0.05 0.05 0.03
## PNKP 20.73 20.34 20.26 30.73 20.46 23.72 23.57
## BEST2 0.09 0.05 0.03 0.06 0.00 0.06 0.08
## PHLPP2 4.40 3.93 3.56 8.04 6.47 6.31 7.05
## SPDL1 17.47 19.11 18.36 19.06 20.55 17.71 21.13
## STAU2 30.97 27.39 28.24 23.01 27.44 27.72 29.63
## PQLC2 12.86 13.47 11.90 24.22 20.32 18.24 19.10
## CTNS 8.20 8.98 8.19 20.65 13.97 16.24 14.33
## RTN4R 3.30 2.53 3.29 7.01 5.42 5.33 4.40
## PHF23 35.95 32.61 34.88 35.75 37.80 33.79 36.01
## CDH10 0.10 0.04 0.02 0.00 0.02 0.00 0.00
## INPP4A 2.86 2.42 2.49 3.22 3.07 2.89 2.76
## RAB27B 12.16 10.05 9.66 8.46 8.37 11.07 9.99
## PSMA4 197.92 212.82 185.98 187.50 225.51 191.02 217.27
## MYO16 0.02 0.07 0.03 0.03 0.00 0.07 0.02
## LSG1 62.99 56.82 59.55 81.97 75.68 85.08 82.03
## PARP3 10.06 10.84 10.18 8.10 6.22 8.99 7.52
## TNC 0.12 0.10 0.06 0.01 0.01 0.12 0.13
## THAP3 16.79 16.89 16.08 18.69 20.23 13.37 15.90
## FAM65C 4.66 4.40 4.67 3.00 2.88 2.70 3.64
## TDP1 23.20 23.60 23.70 21.08 25.49 24.00 24.16
## AIFM2 0.57 0.72 0.91 0.88 0.55 0.75 0.80
## C2orf83 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SPATA7 12.20 11.31 12.40 9.35 10.61 11.07 10.62
## MED17 39.56 34.37 32.10 40.35 36.34 37.76 39.35
## RETSAT 29.93 31.96 32.12 33.28 32.26 35.50 31.71
## CAPG 100.07 107.48 96.62 73.38 94.93 79.37 84.04
## AP2S1 262.44 263.26 265.55 248.38 282.57 249.76 268.01
## USH2A 0.04 0.06 0.05 0.03 0.03 0.02 0.03
## ZPBP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TG 0.00 0.00 0.00 0.00 0.20 0.00 0.00
## ADAM28 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## BARX2 2.81 1.62 1.80 0.87 1.10 1.98 1.31
## DCUN1D1 45.15 31.88 32.85 39.47 46.77 46.15 49.14
## JADE2 6.11 5.84 5.85 8.37 7.49 9.52 7.71
## ZIC2 3.40 4.23 4.75 4.34 4.28 4.40 3.96
## LCP2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TRIT1 16.53 15.18 17.18 15.39 15.46 15.09 17.10
## ADRB1 0.16 0.13 0.13 0.13 0.26 0.11 0.27
## GUCA2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CUL7 14.59 13.33 13.78 15.02 12.34 12.89 14.00
## CTNNA1 174.15 157.70 160.56 192.94 187.40 173.85 186.19
## PHKA2 24.47 26.20 28.28 22.37 19.97 23.95 23.24
## CNTLN 2.40 2.03 2.44 2.27 2.44 2.62 2.42
## EPHA3 0.01 0.00 0.01 0.00 0.00 0.01 0.01
## HSPA5 763.15 732.20 787.25 951.88 775.16 993.36 800.63
## DSG2 25.54 21.18 22.14 22.26 25.42 27.45 27.32
## GEMIN8 22.40 22.59 23.81 18.20 23.69 21.45 20.01
## OFD1 27.39 33.26 30.33 32.52 29.97 31.69 31.97
## GPM6B 0.38 0.54 0.65 0.36 0.31 0.44 0.30
## MAGEC2 0.39 0.28 0.38 0.13 0.27 0.29 0.17
## PREX2 0.00 0.00 0.01 0.00 0.00 0.00 0.01
## WDR37 10.82 9.63 10.02 14.76 11.03 12.70 12.81
## YTHDC2 11.79 11.40 10.46 9.08 9.40 10.61 11.31
## CTPS2 26.83 28.08 25.52 24.00 23.66 24.65 25.90
## ATP6V1H 84.01 78.54 79.82 116.98 104.63 110.59 101.26
## POLR2B 54.22 50.00 49.13 50.00 53.09 55.13 58.49
## FAM214A 54.65 56.69 54.11 60.88 48.39 57.87 54.84
## ARAP2 4.39 4.06 3.55 3.95 4.39 4.45 4.75
## TPR 56.32 57.95 52.51 49.42 53.77 52.68 56.41
## CP 0.50 0.41 0.21 0.15 0.20 0.21 0.23
## KIAA0556 19.17 18.58 16.31 16.48 15.74 15.65 17.75
## DTNBP1 16.37 17.42 14.45 23.50 22.88 20.13 21.43
## XK 1.65 1.20 1.29 1.05 1.33 1.22 1.50
## ANO2 1.34 1.15 0.78 0.27 0.76 0.40 0.72
## C12orf4 3.14 2.50 2.74 4.66 4.74 4.92 4.65
## SCML1 7.21 8.17 7.66 17.09 11.55 12.74 12.33
## WWC3 56.16 50.87 52.74 48.87 51.49 51.32 59.58
## ARHGAP6 0.00 0.00 0.01 0.00 0.01 0.00 0.00
## FAM184B 2.10 2.23 2.18 2.44 1.62 1.94 2.07
## MAP4 37.70 32.46 33.26 46.30 41.95 42.73 44.84
## GOPC 13.91 13.94 13.24 14.09 13.47 14.77 14.61
## ROS1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## USP28 12.91 10.64 9.71 12.65 11.88 14.01 13.15
## HDAC9 1.15 0.56 0.37 0.51 0.76 0.64 0.57
## TSPAN17 19.67 15.78 17.35 22.75 24.65 21.96 24.77
## NOP16 30.35 25.39 28.65 28.14 35.24 27.99 33.16
## CC2D2A 4.19 2.59 3.93 1.60 2.00 2.68 2.44
## RRM2B 22.92 15.58 16.71 19.77 24.69 30.28 23.71
## ZNF800 5.09 3.88 4.41 4.86 5.38 5.77 5.58
## TNFRSF17 0.00 0.00 0.00 0.04 0.00 0.00 0.00
## SNX29 2.67 2.12 2.11 1.91 2.36 2.33 2.44
## LMO3 0.38 0.28 0.25 0.29 0.47 0.10 0.09
## MRPS10 74.68 65.84 62.50 91.50 93.68 92.60 86.58
## GUCA1A 0.05 0.00 0.00 0.00 0.00 0.02 0.02
## RSF1 14.52 11.24 12.32 13.97 12.05 15.63 14.14
## VPS13D 17.35 19.14 17.11 15.03 14.72 14.04 14.92
## CELF2 0.01 0.00 0.00 0.00 0.00 0.01 0.00
## FAM120A 63.07 59.47 56.35 58.48 64.02 61.06 68.66
## R3HDM1 15.06 12.62 12.17 14.84 14.05 12.80 16.00
## COL9A2 13.80 14.09 13.35 12.36 10.28 13.11 11.69
## KITLG 13.09 7.65 8.37 10.02 11.09 13.81 12.15
## ERCC8 19.66 16.75 15.06 16.79 17.64 18.16 21.66
## ADAMTS6 0.07 0.06 0.04 0.03 0.05 0.05 0.04
## H6PD 5.39 4.75 5.26 4.11 4.25 5.50 4.82
## VAMP3 72.56 61.55 62.93 70.70 74.15 74.12 72.42
## PER3 8.43 9.49 9.46 10.27 9.28 11.65 9.02
## UTS2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TNFRSF9 0.02 0.00 0.00 0.00 0.00 0.00 0.01
## EPN3 69.85 72.73 67.78 77.23 62.44 72.74 63.11
## LTBP1 13.86 14.77 12.29 8.32 12.14 8.61 12.22
## RCN1 103.39 87.66 92.10 79.72 93.04 89.15 90.52
## ELN 0.08 0.10 0.02 0.01 0.06 0.00 0.14
## RFC2 65.18 70.12 65.96 51.27 71.40 54.32 63.37
## ARID1B 9.93 8.58 9.35 8.09 8.51 9.78 10.00
## CLPTM1L 242.81 205.71 215.47 182.80 214.54 196.64 220.30
## NEDD4L 18.87 15.40 17.70 22.85 20.99 20.23 20.29
## FOXP3 1.14 0.75 0.86 0.51 0.43 0.86 0.66
## PPP1R3F 3.20 3.00 3.59 2.22 1.75 2.07 1.99
## HEXB 144.01 156.82 144.78 256.18 195.48 249.38 195.08
## PTCD2 14.87 11.91 12.84 15.17 13.70 17.05 14.88
## KIAA2022 0.20 0.21 0.19 0.09 0.10 0.13 0.14
## JKAMP 67.79 73.87 67.21 80.03 84.00 76.87 81.56
## DKK3 0.06 0.03 0.04 0.00 0.00 0.02 0.12
## ARHGEF5 7.92 7.27 7.34 10.16 9.52 9.64 9.94
## NFE2L3 1.10 1.30 1.41 1.13 1.00 0.85 0.95
## MCUR1 14.11 16.35 16.68 21.40 21.30 21.85 19.41
## LIMA1 48.42 46.98 44.20 57.49 50.94 60.44 51.02
## LETMD1 108.96 123.92 119.28 106.30 90.16 117.34 103.18
## SLC4A8 6.50 8.79 8.18 7.42 7.35 7.56 8.46
## LAMC3 0.05 0.05 0.02 0.14 0.04 0.05 0.01
## PTGER3 52.20 35.36 35.81 43.06 50.09 54.10 51.56
## TNIP3 0.00 0.04 0.00 0.00 0.00 0.05 0.11
## MAPK9 38.19 36.99 34.25 34.96 45.07 39.15 46.60
## COL23A1 0.01 0.07 0.09 0.03 0.04 0.01 0.02
## BCAR1 23.27 23.80 23.97 40.31 28.68 29.95 27.34
## FAM160A2 16.32 18.58 18.97 22.09 16.81 21.63 19.18
## HERPUD1 58.92 50.36 63.38 113.72 57.26 98.15 66.16
## HOMER3 20.92 21.97 21.67 41.71 29.76 33.64 28.63
## RAD51 21.33 24.56 21.77 23.74 28.08 22.04 27.94
## POLQ 2.14 2.86 2.45 3.02 2.91 2.19 3.12
## PIK3CB 33.58 31.69 29.05 29.61 31.58 32.84 34.89
## CYBA 0.51 0.40 0.60 0.42 0.11 0.54 0.40
## THOC3 47.37 49.51 52.64 43.66 44.15 43.14 43.85
## HEBP2 101.00 98.68 100.03 97.34 105.40 93.45 98.23
## MPHOSPH9 16.45 17.85 15.39 24.95 16.99 21.73 16.89
## PLEKHA5 6.01 6.24 5.94 4.11 5.73 6.44 5.61
## PRSS8 56.65 66.12 64.79 107.30 59.55 75.38 65.40
## SIKE1 22.17 19.06 16.64 17.53 19.62 24.09 22.38
## RRP12 35.93 28.39 30.95 29.40 37.10 34.85 37.48
## FNIP2 2.33 2.81 2.14 8.64 5.22 6.92 5.32
## MSMO1 24.27 20.35 20.36 35.80 26.96 27.44 27.51
## TTC17 68.95 80.35 71.65 67.30 57.59 67.05 66.12
## ALX4 0.02 0.05 0.04 0.05 0.01 0.04 0.01
## FSTL4 0.04 0.06 0.04 0.04 0.01 0.05 0.00
## FOXN3 5.67 4.50 4.43 8.70 6.14 8.73 7.38
## METTL24 0.00 0.00 0.00 0.00 0.00 0.03 0.00
## AKR7A2 78.80 73.85 74.74 50.78 68.47 65.26 70.39
## MRTO4 28.60 26.36 28.57 20.87 27.58 24.71 26.96
## NNAT 0.85 0.66 0.77 1.50 0.60 0.84 1.45
## USE1 18.31 18.12 17.73 15.05 17.00 17.56 16.00
## MCF2L2 1.72 1.61 2.01 1.22 1.13 1.46 1.48
## NRIP2 0.89 0.73 0.66 1.18 0.71 1.30 1.00
## LAMA3 8.52 9.24 9.42 9.33 7.93 9.33 8.50
## AP5M1 27.28 24.66 22.18 28.61 29.42 26.90 30.02
## ANAPC4 13.47 15.34 12.16 14.13 13.96 14.09 13.97
## KCNQ1 0.30 0.12 0.25 0.14 0.32 0.07 0.16
## TRAPPC3 59.26 51.38 57.08 82.09 78.73 72.63 74.99
## THRAP3 45.80 41.24 42.78 48.43 44.31 48.52 49.95
## PHPT1 141.70 132.92 137.57 116.54 118.68 127.85 121.70
## ENTPD2 52.83 56.11 57.08 47.93 46.04 45.44 50.02
## LY75 0.18 0.05 0.07 0.06 0.03 0.07 0.05
## ARID4B 20.83 19.91 17.06 17.04 17.34 17.33 21.40
## OPN3 4.50 4.09 3.73 3.91 4.38 3.21 4.23
## SDCCAG8 17.12 17.43 18.12 20.62 19.37 16.75 21.05
## PTPRN 0.18 0.00 0.06 0.01 0.12 0.11 0.11
## HHAT 6.57 7.82 8.27 5.35 4.88 5.58 5.97
## KIF1B 6.36 5.23 4.84 6.49 6.53 7.11 7.11
## FOXC1 1.57 1.85 1.68 1.79 2.60 2.36 2.37
## TBC1D22A 13.45 11.67 12.64 10.55 12.00 13.34 11.34
## SYNE2 17.62 23.47 19.64 23.60 18.15 17.72 18.60
## PLEKHH1 31.11 41.14 35.69 29.55 28.61 25.41 30.28
## ATP9A 6.72 5.53 6.44 7.52 6.26 7.68 7.33
## SPO11 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CBLN4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CHRDL2 0.18 0.34 0.00 3.00 0.75 1.89 0.52
## FAM168A 24.36 18.76 19.34 18.76 20.11 20.93 21.53
## RELT 3.41 4.73 4.87 10.00 6.16 5.84 5.16
## GALC 19.54 15.11 16.66 12.40 14.02 18.63 14.98
## NOP58 69.83 64.12 68.81 52.03 69.70 66.19 71.80
## SZRD1 51.74 44.68 46.28 56.39 54.40 58.68 56.75
## KCNH2 0.20 0.20 0.15 0.28 0.10 0.41 0.17
## CUL1 14.66 13.24 13.13 14.94 17.43 14.78 17.01
## FAM114A2 26.86 20.18 23.04 27.70 27.08 29.25 28.77
## CYFIP2 16.56 13.93 16.02 29.58 15.63 22.27 17.94
## TAB2 38.00 32.28 31.15 31.24 33.86 34.54 37.00
## GINM1 38.72 35.13 34.81 39.85 41.25 39.49 42.17
## EIF2AK2 7.63 6.91 6.32 5.60 6.75 8.50 7.04
## USP36 34.73 27.46 31.95 60.23 43.02 51.72 46.65
## KMT2C 7.76 6.83 7.54 8.53 6.84 7.07 8.22
## MCOLN3 4.08 4.39 4.56 15.44 8.37 14.12 9.13
## CCDC85A 2.95 2.94 2.65 1.57 2.32 1.70 2.58
## PUM2 24.21 21.67 21.00 26.65 23.90 28.12 26.86
## MRPL43 156.88 146.85 147.07 125.57 149.23 131.21 140.49
## ITIH4 2.82 2.25 3.76 2.26 1.66 1.73 2.83
## ITIH1 0.00 0.00 0.17 0.00 0.00 0.02 0.01
## C4orf27 29.98 30.08 27.07 26.53 31.40 27.50 30.62
## ZFR 30.10 21.76 22.97 35.89 32.93 34.78 33.40
## ZNF280C 0.86 0.85 0.92 1.14 0.97 1.08 1.32
## NPFFR2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PHF21B 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## TRAF1 1.28 1.59 1.72 1.68 1.21 1.57 1.30
## RC3H2 26.42 16.70 17.67 40.30 23.68 26.31 43.63
## PCGF2 70.94 85.30 82.41 74.03 60.77 66.33 61.01
## IL17RB 14.57 22.03 18.38 21.80 21.93 17.56 21.29
## TRAF3IP2 23.04 25.68 24.25 19.92 21.59 17.91 21.09
## GYG2 6.47 5.02 5.36 2.70 3.48 3.32 3.18
## DCBLD2 13.40 11.66 10.66 12.03 12.48 13.36 14.17
## SERPINB3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SOAT1 17.08 12.98 13.73 16.05 16.60 22.54 17.81
## PKP2 10.15 8.18 8.84 7.66 8.27 10.96 8.74
## MSH4 0.00 0.00 0.00 0.00 0.00 0.02 0.00
## F7 0.55 0.61 0.52 0.77 0.50 0.48 0.50
## GDI2 234.31 214.82 219.14 212.88 250.87 237.49 253.67
## PRDM1 0.52 0.60 0.28 0.17 0.20 0.30 0.63
## ATG5 14.13 12.41 12.67 15.32 14.67 14.26 14.59
## TMCC3 0.02 0.00 0.02 0.00 0.03 0.01 0.01
## PITHD1 37.98 39.37 35.44 42.14 42.18 37.91 40.79
## MTA3 33.90 33.57 33.80 22.39 27.64 27.83 26.92
## USP13 12.91 11.17 10.75 10.53 12.88 15.33 14.18
## ATP11B 9.51 8.74 7.84 8.10 9.45 9.37 9.96
## LAMC2 2.69 2.76 3.05 2.73 3.29 3.65 2.84
## CDK14 2.77 3.04 3.38 2.04 2.88 2.67 2.81
## SEC61A1 121.97 110.81 115.85 140.43 131.06 136.63 142.27
## PPP1R12A 23.84 19.91 18.97 27.37 25.47 27.83 29.30
## RASGRF1 0.19 0.17 0.17 0.11 0.07 0.11 0.14
## CAMK2B 2.84 2.61 2.54 1.10 1.41 1.28 1.42
## CROCC 9.62 13.39 11.18 19.77 11.21 10.06 12.72
## POLR3E 42.87 44.06 39.06 36.54 35.10 32.88 38.25
## ATP2B4 9.40 8.44 9.33 7.48 8.08 10.06 8.78
## ZC3H11A 75.25 76.96 69.86 61.26 66.92 61.52 69.20
## RIOK2 30.50 31.11 33.32 39.86 34.59 33.14 35.87
## YIPF1 59.19 49.48 54.00 40.85 46.08 48.99 50.92
## NDC1 23.85 16.62 18.55 16.80 19.80 26.35 21.15
## DGKG 0.01 0.00 0.00 0.00 0.00 0.01 0.00
## FLYWCH1 19.49 20.01 21.86 54.22 25.59 30.96 25.39
## UNKL 20.00 24.26 20.85 57.56 29.06 46.70 31.28
## TBXAS1 1.56 1.50 1.66 0.93 1.50 1.23 1.37
## PARP12 10.17 11.20 12.45 7.97 8.55 8.93 9.59
## ALDH18A1 52.69 50.36 52.92 29.66 40.69 38.85 44.55
## TARBP1 10.92 16.51 14.92 16.10 14.39 14.81 14.60
## PET112 16.62 17.18 15.93 16.02 16.19 15.63 15.47
## MXD1 2.58 3.20 3.40 6.12 3.39 4.11 3.63
## CDK17 13.42 14.01 13.15 11.42 12.38 13.73 13.29
## DNAJC25 8.67 30.77 31.48 30.14 33.22 10.28 28.31
## SLC2A3 0.00 0.07 0.05 0.00 0.01 0.01 0.06
## PSD 1.70 2.48 2.68 4.83 1.85 3.52 2.13
## CTDP1 5.98 5.23 4.83 8.05 6.44 6.10 6.51
## YBX3 40.07 40.51 42.99 38.10 42.52 41.48 42.82
## STYK1 2.09 2.53 1.78 2.71 2.56 3.24 3.14
## WNK1 47.44 44.61 40.18 47.72 43.25 49.04 52.25
## CCAR1 70.70 67.86 67.91 68.66 72.42 63.76 69.02
## OGFR 26.26 26.90 27.90 16.40 21.37 18.51 20.92
## GNA15 0.02 0.05 0.05 0.01 0.00 0.01 0.00
## CREB3L3 0.00 0.04 0.00 0.04 0.00 0.02 0.00
## PIGV 12.92 13.81 12.19 9.86 9.67 10.62 9.78
## PTPRU 9.14 8.33 8.73 6.12 6.23 7.70 7.15
## SNRNP40 30.61 26.79 27.82 26.79 31.77 28.41 30.12
## RIMBP2 0.01 0.01 0.06 0.01 0.00 0.00 0.00
## COL11A1 0.00 0.00 0.00 0.05 0.00 0.05 0.00
## QSER1 10.32 9.68 9.37 9.62 10.78 10.33 12.55
## MPC1 46.90 51.81 49.91 89.63 67.75 67.92 66.30
## ACAA1 56.96 60.19 61.10 62.24 60.05 59.07 60.25
## BCAT1 0.03 0.00 0.00 0.01 0.00 0.01 0.00
## HDAC7 25.69 29.92 27.31 24.47 22.49 24.29 24.25
## LZTS1 0.05 0.00 0.01 0.00 0.01 0.00 0.00
## PRDM6 0.39 0.55 0.48 0.49 0.56 0.45 0.64
## WNT8A 0.00 0.00 0.00 0.02 0.00 0.00 0.00
## SPAG4 32.03 17.17 28.14 11.68 15.84 14.78 13.75
## NCKAP1 42.00 32.44 33.25 54.71 51.93 55.31 52.98
## MRPS35 83.22 66.97 70.40 68.04 77.82 81.56 81.47
## GUCY1B3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SFSWAP 39.48 43.74 40.08 40.88 37.16 35.95 38.51
## TNK2 100.47 141.64 121.89 130.62 107.41 98.12 110.10
## MON2 35.47 37.66 35.63 32.81 31.86 31.03 34.66
## CDH3 21.90 19.10 22.94 22.48 21.40 23.93 22.44
## ARSF 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GPBP1 98.45 107.74 99.48 106.54 100.81 91.84 100.69
## DGAT2 1.55 1.37 1.41 1.52 0.90 1.36 1.33
## ZNF112 2.72 2.55 2.29 2.84 2.38 2.74 2.25
## CS 186.99 182.83 182.01 200.67 196.11 207.35 207.53
## LTK 0.34 0.44 0.37 0.26 0.25 0.24 0.25
## MRPS24 163.38 157.48 154.94 154.84 176.76 162.61 159.70
## ELMO2 35.64 36.75 35.46 45.22 36.96 32.74 38.61
## WAPAL 30.09 29.18 27.48 29.46 29.77 28.78 29.66
## VMP1 138.22 147.98 140.48 138.64 125.59 152.02 138.97
## APPBP2 23.45 16.99 17.99 18.58 18.57 19.96 23.72
## POLD1 17.42 18.49 16.78 21.24 21.22 15.96 20.89
## SEZ6 0.25 0.01 0.12 0.05 0.00 0.00 0.04
## EIF4B 289.32 205.93 228.75 230.77 212.18 307.79 250.66
## SLC6A16 0.52 0.86 0.69 0.82 1.05 0.53 0.40
## GLTSCR1 4.13 3.11 4.44 4.75 3.41 3.65 3.74
## SPHK2 6.32 6.74 6.94 8.36 6.57 6.93 6.99
## RPL18 1387.32 1270.61 1308.90 1197.49 1257.38 1313.29 1249.68
## CA11 20.12 20.10 19.45 15.98 16.31 17.42 18.22
## ISOC2 71.32 70.37 69.55 76.35 77.15 66.14 70.07
## U2AF2 95.98 86.86 83.82 97.26 94.64 85.93 94.19
## EPN1 48.19 44.51 46.64 53.95 51.83 44.61 50.00
## MED29 26.60 23.47 24.89 26.62 26.41 29.47 27.97
## AHRR 0.61 1.29 1.21 0.97 0.59 0.36 0.41
## GSC2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZNF275 1.29 1.18 1.51 0.67 1.05 1.29 1.05
## MTMR1 19.67 17.23 17.38 14.82 18.27 17.27 21.25
## GPC1 22.12 28.60 29.41 33.79 26.49 25.36 27.11
## ADCK1 9.87 9.88 8.49 12.44 10.10 10.26 10.13
## HAGH 51.52 62.91 53.21 57.28 66.47 59.75 63.00
## RNF4 43.18 36.05 38.11 45.09 47.36 47.75 49.85
## CASP8 12.74 9.88 12.30 11.97 11.23 12.41 12.90
## LIMCH1 4.89 3.57 4.26 4.13 3.87 5.18 3.75
## ASUN 29.71 29.88 29.59 28.91 31.66 27.76 33.67
## TM7SF3 59.16 55.07 52.80 56.62 59.44 67.46 65.53
## DLX3 17.47 16.95 18.49 18.37 14.55 19.26 15.23
## SPA17 87.39 86.27 85.02 37.41 76.23 56.65 70.48
## TSPAN32 0.04 0.04 0.11 0.12 0.00 0.00 0.01
## WISP2 3.32 2.86 4.58 1.76 2.35 1.57 1.95
## DMRT3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ST3GAL6 0.18 0.39 0.24 0.26 0.26 0.38 0.31
## ATP2C2 11.28 11.54 13.02 16.08 11.26 18.41 13.83
## NGFR 3.07 2.53 3.91 6.66 2.52 9.62 2.62
## CDON 3.47 3.10 3.83 5.20 4.20 5.82 4.03
## TAF2 18.93 15.94 15.79 17.15 15.90 17.06 18.01
## HIPK2 4.33 3.99 3.95 4.06 3.34 4.34 3.93
## TNPO3 17.57 14.71 15.60 19.27 17.99 20.26 19.98
## MEF2BNB-MEF2B 0.68 1.60 0.97 1.28 1.41 0.85 0.75
## RFXANK 85.50 78.85 84.26 67.99 81.07 61.91 69.45
## TMEM161A 20.14 20.00 20.52 19.63 18.90 19.98 18.89
## LPAR2 13.78 15.22 14.69 14.72 16.16 14.34 14.77
## CTSA 157.30 172.96 174.94 362.99 190.87 284.49 219.30
## SUGP2 28.32 29.64 27.90 38.33 32.77 30.57 30.95
## SLC12A2 3.88 2.84 3.80 4.61 4.41 4.17 4.70
## SNX24 26.11 23.03 23.85 27.89 35.23 23.56 35.88
## EYA2 2.98 2.41 1.93 1.20 1.82 1.47 1.95
## CNN2 166.17 160.58 170.08 129.83 147.65 131.13 147.69
## ABCA7 9.33 11.17 9.19 8.37 10.57 7.78 10.48
## SNCAIP 0.29 0.26 0.36 0.04 0.15 0.12 0.22
## DDX20 10.34 7.87 8.72 8.37 10.91 9.91 11.31
## BTBD1 36.39 27.72 31.03 26.81 31.85 33.46 33.28
## FAR2 2.22 1.64 1.35 1.89 1.30 1.06 2.42
## BCAS1 20.85 22.23 20.41 13.58 10.58 14.08 13.33
## POU1F1 0.00 0.00 0.03 0.00 0.00 0.02 0.04
## CHI3L2 0.11 0.25 0.14 0.17 0.20 0.07 0.04
## SBNO2 22.15 22.96 24.75 38.40 26.08 34.70 27.62
## PMS1 7.24 6.48 6.31 7.05 7.16 6.49 7.01
## HMG20B 211.60 241.78 225.74 229.50 197.16 182.46 213.94
## CALCRL 0.00 0.00 0.00 0.00 0.02 0.01 0.00
## TAF11 49.24 47.23 45.70 50.46 51.89 46.71 50.87
## ANKS1A 6.90 5.26 5.74 5.27 5.74 5.95 6.26
## AP3D1 41.23 39.35 39.58 63.46 48.34 51.84 52.85
## ZNF76 26.67 28.84 26.04 36.46 23.83 27.52 26.52
## SLC9A3R2 130.05 128.54 132.42 79.35 95.08 79.50 97.74
## NTHL1 23.95 24.00 25.07 14.85 18.28 18.10 17.36
## UHRF1BP1 10.35 8.56 8.40 10.64 10.14 11.53 11.25
## GNAI3 42.99 34.49 34.52 40.99 50.45 47.97 51.04
## IPO5 29.17 25.54 26.53 28.47 31.17 31.94 32.77
## OAT 87.01 90.61 83.80 80.22 80.06 84.07 81.90
## WDR3 17.07 13.93 13.79 13.32 16.98 17.66 18.84
## PKN2 14.31 13.52 13.41 13.22 13.50 14.95 14.75
## WDR18 38.36 36.96 37.58 35.66 38.29 37.34 36.08
## TRAM2 13.51 9.76 10.08 9.53 10.23 12.02 12.03
## NTN1 12.47 11.30 11.38 7.32 11.29 8.90 11.09
## GLP2R 0.00 0.01 0.00 0.00 0.00 0.01 0.00
## MCM10 9.37 9.17 9.39 7.48 11.07 7.88 10.90
## DGKA 32.67 35.61 36.23 24.73 32.85 32.70 34.90
## ERBB3 186.08 199.74 188.58 187.64 159.50 185.85 169.90
## ROPN1 0.00 0.00 0.05 0.00 0.07 0.03 0.02
## ANKRD44 1.70 2.14 1.65 2.24 1.99 0.89 1.76
## KARS 128.00 116.40 121.60 121.60 139.35 121.99 138.05
## ADAT1 43.96 43.58 40.52 48.04 49.34 48.20 49.90
## PDIA5 16.12 16.50 19.25 12.23 13.36 14.56 12.37
## TBC1D22B 6.51 5.72 5.70 8.21 6.15 6.84 6.66
## NDUFB4 312.55 326.64 323.63 342.53 389.04 332.07 378.92
## SPEN 6.19 7.39 8.24 8.61 6.93 6.02 6.89
## MYLK 1.32 1.30 0.93 0.59 0.72 0.83 0.64
## ZC3H15 44.14 37.29 38.93 40.30 45.99 42.56 45.99
## MAP2K4 13.42 11.87 11.42 12.91 15.33 14.03 14.35
## TMEM206 22.36 18.50 17.43 14.68 21.50 15.07 24.35
## SNAP91 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SLK 9.93 8.78 8.58 15.25 12.71 14.41 12.66
## CYB5R4 6.51 5.34 5.83 5.25 5.93 5.66 6.74
## COL17A1 0.02 0.01 0.05 0.00 0.02 0.08 0.07
## GSTO2 73.65 71.84 72.63 50.38 59.49 69.62 56.95
## SEC61A2 7.84 9.60 8.48 13.40 11.97 12.09 12.25
## PRKCQ 0.02 0.01 0.00 0.00 0.00 0.00 0.00
## TLE2 17.80 15.26 14.17 12.27 12.09 12.10 14.07
## ASB1 12.27 12.11 13.62 11.89 10.31 10.60 11.56
## FAM107B 33.85 23.58 25.10 25.73 28.52 36.56 30.57
## ME1 0.02 0.00 0.04 0.00 0.00 0.00 0.01
## TBC1D1 10.87 12.01 10.01 8.59 11.18 11.69 10.34
## CDK13 15.25 14.63 12.95 17.88 13.88 13.99 16.25
## MTHFD2 177.84 165.34 161.02 204.30 177.74 206.70 185.15
## SLC9A7 10.89 10.26 10.81 9.26 10.52 13.52 11.47
## FOXJ2 3.21 2.75 2.97 3.78 3.62 4.05 4.26
## YBX1 239.92 228.82 233.57 245.91 282.97 248.98 266.93
## PDE4A 0.75 0.62 0.63 0.60 0.61 0.63 0.71
## PPP2R5A 48.98 44.03 43.10 46.95 46.53 48.38 47.33
## CTNNA2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ELAVL1 49.55 40.88 40.50 44.60 53.07 47.21 52.22
## TIE1 0.03 0.00 0.01 0.06 0.01 0.06 0.05
## DIP2B 18.71 16.04 17.01 22.44 18.94 24.23 20.83
## SMARCD1 52.13 47.84 48.94 52.10 50.83 51.17 49.93
## KDM4A 14.44 11.80 12.16 14.65 13.05 14.60 13.57
## NFYC 25.85 25.29 25.03 26.53 22.57 25.45 23.76
## ZMYND12 0.26 0.21 0.18 0.08 0.11 0.10 0.09
## SLC9A3 0.29 0.14 0.18 0.16 0.12 0.17 0.19
## NGEF 23.31 22.58 24.18 21.55 22.87 21.97 20.32
## ASPM 14.74 19.71 16.00 13.47 17.59 15.51 17.01
## CD84 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ELOVL1 103.54 107.88 103.53 95.63 113.98 95.89 118.79
## SPI1 0.20 0.00 0.09 0.17 0.03 0.08 0.00
## ZNRD1 69.37 60.44 61.66 56.88 68.69 73.35 68.09
## MPPED2 3.37 3.20 3.39 1.10 2.52 1.61 2.32
## CLDN18 0.02 0.00 0.00 0.00 0.00 0.00 0.03
## ZBTB11 14.41 12.87 12.66 14.06 14.29 14.04 15.07
## ATXN3 23.56 21.83 24.97 21.28 21.14 27.48 24.17
## GOLGA5 65.27 68.18 61.99 55.68 54.70 52.86 58.26
## FGFR2 26.38 19.67 17.97 17.06 16.88 21.66 19.40
## LRRC40 10.57 10.12 9.77 9.75 11.11 10.05 10.89
## ISOC1 28.10 29.55 27.51 26.51 29.79 24.85 27.66
## EML1 6.84 5.51 5.99 4.04 4.97 5.31 5.04
## TRMT11 13.03 12.51 12.02 13.59 12.81 13.75 13.61
## THUMPD1 22.33 20.06 20.35 18.60 19.20 20.71 20.85
## MSANTD3 5.86 5.24 5.23 6.70 7.93 7.65 6.95
## KIF26A 0.33 0.29 0.40 0.10 0.21 0.19 0.24
## ATG2B 8.72 7.88 8.30 14.27 8.39 14.52 11.72
## ARFGEF1 67.63 63.43 60.78 57.39 63.47 53.36 64.55
## ACSM2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZFAT 3.17 3.30 2.46 3.40 2.81 2.40 2.22
## MTFR1 52.31 54.15 53.68 73.92 64.88 66.77 65.96
## STAG3 1.34 1.09 0.98 1.75 1.22 0.95 1.12
## FECH 28.08 19.83 20.24 35.39 34.85 42.91 39.89
## MYO9A 6.18 4.30 4.35 7.89 6.02 7.64 6.47
## DDX3Y 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PFKP 51.62 31.17 51.31 67.33 58.32 64.47 54.57
## IDI1 87.85 86.64 77.90 135.43 104.62 91.85 102.84
## SP100 12.17 11.24 10.39 8.43 11.39 11.24 10.91
## KLF6 18.22 11.70 12.62 22.07 20.40 22.50 22.89
## PPAP2A 18.72 18.95 18.57 16.34 20.82 16.58 20.02
## NEO1 9.65 5.98 6.33 6.76 6.38 7.05 7.32
## TRAM1 132.92 94.36 99.03 103.31 120.45 128.63 133.56
## PHKA1 2.81 2.17 1.83 2.45 2.41 2.80 2.79
## TNFRSF1A 24.83 24.96 23.08 30.70 25.54 25.10 27.78
## CACNB1 14.72 18.04 16.91 20.48 16.60 17.32 15.50
## EVI5 3.23 2.05 2.46 2.79 2.76 3.90 4.20
## STOML1 8.91 9.06 8.75 10.74 10.25 10.58 9.74
## PKM 829.44 634.79 744.01 788.00 857.00 758.36 828.59
## DHX29 25.56 24.25 23.45 29.15 31.18 30.89 34.04
## DNTTIP2 30.39 31.28 34.06 41.63 40.83 36.01 35.60
## METTL22 18.18 25.32 23.62 24.90 21.48 23.63 18.67
## TP53BP1 26.84 25.30 27.72 19.96 21.22 22.27 24.02
## TRO 0.10 0.03 0.01 0.03 0.00 0.03 0.02
## RRP15 24.02 14.19 16.84 15.92 22.24 21.27 20.34
## RHOA 213.80 195.56 194.49 203.76 233.80 218.46 225.47
## DHX8 25.91 26.13 25.37 27.64 28.72 28.23 30.37
## PRKCZ 22.47 19.84 19.25 21.98 17.99 18.53 19.99
## ZFY 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## IARS2 146.97 126.05 124.68 123.39 150.12 141.92 158.55
## SYT1 7.07 5.65 6.06 4.81 5.78 6.19 6.50
## NAV3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## IDH3G 29.92 31.02 29.57 43.75 35.79 30.10 34.31
## ROGDI 67.69 71.52 69.11 59.97 47.15 56.33 51.29
## PDZD4 2.50 2.01 2.35 1.78 2.49 1.36 1.91
## ATP2B3 0.00 0.00 0.01 0.01 0.00 0.00 0.00
## ROCK1 14.80 12.31 12.56 15.55 16.51 15.33 17.62
## CBFB 22.52 21.77 20.90 23.65 23.39 23.37 22.59
## PDK3 10.04 9.52 9.98 8.67 10.35 11.91 10.56
## HYAL2 22.75 24.29 23.65 20.91 24.68 20.69 24.20
## HDAC4 1.26 1.10 1.34 1.19 1.94 1.33 1.31
## RASSF1 15.89 15.96 16.75 17.61 17.97 15.91 17.78
## FGFR3 27.35 28.58 28.70 17.16 23.32 20.32 23.88
## IFI35 37.49 37.46 38.68 38.50 35.59 44.40 37.39
## HEATR6 14.56 16.17 15.24 13.49 11.22 15.16 12.80
## COASY 144.57 149.45 145.12 112.86 139.64 127.69 137.45
## PLEKHH3 60.10 60.35 57.77 77.03 67.62 61.16 64.54
## MEF2A 11.20 10.97 11.84 17.77 12.78 16.48 15.83
## OTUD5 45.39 43.50 42.15 38.42 38.08 34.22 38.15
## TFE3 32.18 29.98 30.97 52.79 44.50 40.82 44.62
## TBC1D25 8.21 6.50 5.55 7.03 7.49 7.47 6.83
## ACSL4 0.19 0.19 0.24 0.22 0.19 0.39 0.32
## INPP5A 13.38 12.71 12.97 12.95 12.59 12.17 13.54
## GPKOW 35.80 33.41 33.26 30.25 34.61 29.95 34.79
## GRIPAP1 34.66 41.19 36.77 48.54 36.17 42.01 41.56
## FTSJ1 49.04 48.19 49.04 41.03 50.29 44.77 48.17
## PRR11 24.15 24.27 22.63 19.07 25.95 26.36 27.69
## REEP1 1.82 1.42 1.37 1.32 2.13 1.85 2.01
## ATP11A 1.69 1.29 1.77 1.29 1.61 1.35 1.61
## POLR1A 5.35 3.54 4.41 4.62 4.62 5.54 6.07
## LAPTM4A 117.02 114.43 108.80 112.66 125.22 124.06 128.78
## TTC7A 5.15 4.89 4.66 3.71 4.99 4.02 4.97
## IP6K2 74.16 90.68 82.44 73.11 64.88 70.47 68.19
## STON1-GTF2A1L 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SRBD1 4.79 4.93 4.75 6.25 5.55 6.47 5.54
## CYFIP1 56.03 55.54 53.53 47.25 60.34 54.53 61.08
## KIF2A 17.42 12.99 13.67 15.34 18.70 18.38 21.19
## RASGRP2 0.75 0.80 0.88 0.69 0.89 0.24 0.58
## PSME4 29.69 30.83 26.82 28.38 32.62 27.69 31.32
## IFT80 38.26 41.42 37.90 34.33 36.42 45.59 45.01
## SIRT2 32.17 31.73 33.70 64.25 35.44 44.51 41.33
## ERLEC1 66.66 66.50 64.14 49.94 63.35 60.49 68.24
## PPP2R5B 9.16 8.42 9.71 7.12 9.40 5.56 9.04
## PYGM 0.34 0.51 0.39 0.46 0.49 0.29 0.37
## PAGE1 0.00 0.00 0.05 0.06 0.00 0.00 0.00
## PITX1 54.31 53.11 52.19 38.87 43.81 38.02 42.71
## TRPC7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MAST4 2.35 2.38 2.12 2.35 1.69 2.86 1.99
## GPR116 0.01 0.00 0.01 0.00 0.01 0.08 0.07
## SDK2 0.14 0.14 0.06 0.05 0.05 0.03 0.03
## ADAM7 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## NUP133 29.75 28.23 27.29 28.29 30.62 31.01 30.37
## NUCKS1 144.26 137.46 131.66 108.19 126.21 146.45 132.85
## VPS35 43.11 38.99 40.39 62.54 54.19 60.83 58.10
## DNAJA2 42.65 39.04 38.17 41.65 46.97 42.14 44.71
## BCL3 13.35 18.75 17.74 13.28 13.09 11.80 13.36
## KCNAB2 4.87 4.46 4.93 15.09 6.94 12.65 7.96
## ABCC9 0.02 0.02 0.03 0.00 0.01 0.00 0.01
## GAL 1.20 1.05 1.67 1.60 1.30 2.35 1.33
## CLEC2D 1.52 2.10 2.04 2.27 1.23 1.11 1.69
## FUNDC1 50.04 51.69 46.96 47.66 45.90 43.47 45.08
## MAOB 0.03 0.05 0.03 0.05 0.02 0.02 0.00
## RORA 0.31 0.31 0.26 0.24 0.27 0.84 0.36
## DRD4 0.27 0.70 0.77 0.77 0.34 0.36 0.27
## TGFBR3 1.34 0.89 0.83 1.41 2.17 1.16 1.80
## KIAA1107 0.99 1.04 1.08 1.10 0.90 0.96 1.14
## PLA2G10 0.11 0.10 0.51 0.07 0.20 0.23 0.08
## HES2 0.82 0.63 0.93 0.67 1.05 1.74 1.25
## ATP1B3 125.85 146.80 121.62 208.11 181.31 150.97 169.86
## NEDD4 10.05 8.53 8.58 9.49 10.40 10.68 10.69
## PIGB 17.27 18.84 17.01 10.38 13.97 11.70 11.58
## MAPK6 26.78 20.08 20.95 58.50 40.16 46.75 41.80
## GNB5 8.38 6.31 5.96 8.25 8.23 6.96 8.21
## RAB27A 9.23 8.68 9.05 9.75 9.75 10.18 10.86
## CECR5 31.59 27.97 32.12 36.92 33.23 34.96 32.79
## UFD1L 48.42 42.52 42.92 62.96 67.67 47.59 60.83
## LRP6 2.89 2.50 2.60 2.39 2.83 3.09 3.33
## GUCY2C 0.00 0.01 0.01 0.01 0.01 0.02 0.00
## SCT 0.16 0.00 0.11 0.00 0.00 0.14 0.00
## PHRF1 7.16 7.52 7.04 8.17 7.48 6.59 8.27
## IKBKAP 31.50 24.19 23.66 27.23 31.75 31.05 33.61
## NUCB2 158.98 178.14 170.21 297.70 200.89 283.18 223.54
## PFN2 61.98 51.09 59.46 74.83 73.42 92.05 77.83
## PTPN3 13.06 11.29 11.52 13.09 12.39 15.94 13.62
## SPTB 0.89 0.96 1.00 0.67 0.87 0.80 0.79
## DAPP1 1.53 1.60 1.73 0.94 1.18 0.88 0.97
## FGF10 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SLC44A1 18.92 15.29 16.21 15.87 16.97 22.54 19.65
## TMEM260 6.45 6.29 6.84 6.49 5.97 8.40 6.79
## SMG6 12.72 13.60 13.17 16.65 13.11 13.03 13.59
## EXOC5 42.72 31.56 30.87 35.32 38.44 50.71 45.07
## CLTCL1 13.17 14.57 13.30 6.41 7.67 7.93 8.39
## FGF22 0.74 0.88 1.07 3.34 1.38 1.70 1.18
## FSTL3 8.22 5.86 6.23 7.65 6.12 8.06 7.35
## DGCR2 21.34 19.68 20.31 21.63 20.62 21.40 22.19
## RNF126 25.02 26.25 25.35 25.33 27.10 21.31 24.03
## MNT 5.71 5.29 7.03 10.86 4.82 8.44 6.21
## ZXDC 12.30 12.77 13.93 15.51 12.65 13.78 12.60
## JMJD6 30.02 26.22 27.83 39.78 40.49 31.29 35.76
## POLB 56.79 51.21 49.87 55.26 62.31 58.76 59.37
## ST6GALNAC1 0.09 0.25 0.06 0.05 0.00 0.13 0.02
## WIPI1 146.37 145.96 136.23 186.02 157.54 150.62 171.47
## FRMPD1 0.01 0.02 0.02 0.01 0.03 0.01 0.02
## GBA2 34.81 36.94 36.02 50.14 39.45 40.04 42.53
## NDST1 40.62 34.56 34.98 24.28 26.82 32.68 31.57
## ASNS 54.90 32.54 40.17 67.24 70.49 83.04 65.74
## AP3M2 19.54 17.60 19.80 15.71 19.11 20.29 18.59
## CNGB1 0.00 0.00 0.06 0.15 0.00 0.00 0.03
## ST6GALNAC2 70.02 85.22 77.61 96.68 66.64 72.95 68.98
## CHAT 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PABPC1 980.16 793.45 871.93 855.83 862.50 1055.70 949.75
## TESK2 8.23 7.80 7.01 14.59 9.05 11.05 9.81
## C16orf80 21.45 22.79 20.59 23.27 27.28 22.60 24.24
## CSNK2A2 25.87 22.75 24.66 26.07 26.51 28.79 26.66
## PTPN21 12.60 10.13 9.30 12.22 10.98 10.85 11.96
## EIF2B3 22.45 22.78 21.75 21.16 26.04 22.50 26.28
## CAMK2A 0.19 0.18 0.11 0.07 0.02 0.11 0.04
## TCOF1 18.09 16.50 16.25 19.26 19.69 17.40 19.65
## CDC42 162.04 151.97 148.67 149.19 174.41 162.35 173.69
## OSBPL3 7.28 6.73 5.80 6.41 7.72 7.40 8.53
## EPHA8 0.74 0.75 0.85 0.33 0.73 0.23 0.47
## SLC12A3 0.06 0.02 0.01 0.01 0.09 0.06 0.04
## RAD18 9.92 9.60 9.33 11.58 11.32 12.04 12.27
## ATP2B1 10.18 7.67 8.21 10.97 13.84 10.73 12.97
## TRPM5 0.02 0.01 0.03 0.00 0.00 0.00 0.01
## NCK2 10.03 8.05 8.97 8.54 9.86 9.24 8.79
## MAP4K4 7.21 4.65 5.85 6.74 7.66 8.96 9.63
## MGAT4A 8.29 6.70 5.52 6.53 9.11 7.27 8.54
## RPL31 1444.27 1526.90 1506.69 1191.06 1327.03 1385.19 1317.17
## WDR1 87.79 71.00 74.42 82.39 92.42 97.45 100.06
## SNX13 24.87 21.64 22.52 28.30 26.14 29.65 27.64
## MS4A12 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ARHGAP10 0.74 0.53 0.60 0.80 0.95 0.81 0.99
## RPS6KA2 0.79 0.43 0.31 0.83 0.82 1.00 0.61
## ING3 5.06 4.08 4.49 3.92 4.65 4.99 4.35
## VASH1 1.45 1.67 2.09 1.09 1.35 1.37 1.21
## LMCD1 37.10 36.87 40.10 23.87 27.43 24.80 27.50
## WBSCR22 145.65 140.79 144.15 137.69 164.41 138.94 153.09
## SEL1L 61.71 47.95 50.51 63.38 54.89 71.90 63.98
## TRIP13 33.11 37.93 34.51 28.70 34.71 29.73 34.48
## ATP6AP1 139.44 149.85 146.48 146.33 143.41 140.75 149.76
## TCF3 35.98 38.37 34.70 34.36 36.74 30.70 33.63
## TRIB2 0.06 0.01 0.01 0.02 0.00 0.01 0.02
## DAZAP1 88.05 90.88 91.12 103.27 106.21 85.68 92.84
## MBD3 27.09 27.75 28.97 29.68 28.65 20.55 26.64
## PRLH 0.00 0.59 0.21 0.27 0.00 0.27 0.00
## HLTF 53.27 52.60 48.20 47.40 51.16 54.47 58.51
## FAM50A 74.36 73.49 70.34 117.27 93.65 83.13 95.30
## FAM3A 32.44 31.48 30.92 38.02 34.32 30.87 35.62
## CPSF1 108.31 136.41 124.15 124.65 113.59 103.45 119.49
## MYO3B 0.22 0.07 0.18 0.03 0.05 0.08 0.09
## CYBRD1 32.86 24.93 26.07 28.98 24.50 30.60 28.74
## CDH19 1.68 1.33 1.30 1.23 1.26 1.06 1.49
## PDCD2 48.06 47.47 40.92 37.43 45.74 39.35 46.72
## SLC6A15 0.00 0.00 0.00 0.02 0.00 0.00 0.01
## RDH11 62.43 60.24 54.18 63.12 69.81 52.25 65.34
## PRKACA 59.01 57.12 56.97 49.45 52.73 53.40 60.10
## LPHN1 11.92 8.77 9.86 6.46 8.61 7.27 9.03
## SPP2 0.00 0.00 0.10 0.00 0.00 0.00 0.11
## ACTN1 72.66 69.94 66.79 77.47 84.31 75.55 85.83
## ZFYVE26 8.54 8.18 7.86 19.48 11.33 14.50 12.51
## RPS6KA6 0.67 0.26 0.47 0.45 0.23 0.44 0.48
## EPN2 19.59 17.64 17.52 13.07 14.90 16.69 16.84
## PTPN18 23.25 29.64 26.03 31.09 23.09 26.92 25.86
## LIMS2 0.36 0.50 0.37 0.31 0.34 0.34 0.34
## ASIC4 0.05 0.07 0.08 0.01 0.06 0.04 0.05
## SPEG 2.57 1.55 2.00 2.62 1.88 1.98 1.91
## LNX1 5.72 5.28 5.66 4.91 3.82 5.58 5.06
## ALDH3A2 54.32 52.09 52.76 82.76 60.75 71.92 66.42
## TFRC 179.65 101.33 110.38 311.13 252.78 310.54 295.98
## SREBF1 100.15 119.17 112.67 127.65 97.79 98.22 117.25
## TRPC5 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## AFF4 21.19 16.49 16.79 34.16 22.67 29.94 26.65
## UBE2D1 15.81 14.75 13.48 17.82 18.92 17.72 17.56
## MPP5 18.41 15.48 14.48 17.13 16.57 19.05 18.47
## RHOBTB1 4.04 4.51 5.11 2.72 3.13 4.61 3.97
## SMC1A 35.14 28.11 25.30 29.80 30.54 35.12 38.75
## HSD17B10 164.04 165.37 155.25 187.10 215.40 165.47 197.16
## MARK2 31.97 28.48 30.82 26.96 28.96 31.41 32.17
## HMMR 51.05 52.64 49.31 42.11 56.89 50.86 56.15
## CHFR 30.36 30.98 30.37 49.79 36.04 35.95 38.09
## TRHDE 0.00 0.00 0.00 0.00 0.00 0.01 0.06
## P4HA2 22.01 18.56 23.14 25.55 21.41 20.96 21.61
## FCGR2B 0.00 0.00 0.00 0.00 0.00 0.09 0.07
## NFATC3 7.65 5.04 5.27 5.79 6.63 8.07 7.58
## TRNT1 15.16 15.82 14.26 13.15 15.68 14.54 14.71
## ACADVL 352.13 406.42 368.10 276.50 287.18 263.72 286.46
## STK10 5.77 5.05 6.72 6.04 5.84 5.61 7.04
## FBXW11 26.27 22.15 21.93 23.35 24.50 27.20 27.72
## ACAP1 11.75 9.25 8.20 4.16 7.00 5.47 8.14
## CRMP1 0.30 0.45 0.51 0.30 0.27 0.44 0.29
## EVC 0.73 0.46 0.58 0.40 0.42 0.65 0.48
## DERL2 69.45 72.41 74.75 80.35 84.19 80.05 86.24
## SIDT1 13.46 11.69 12.79 10.77 9.86 12.59 11.02
## NDE1 38.72 36.18 34.95 31.71 34.29 38.82 36.08
## MRVI1 0.01 0.01 0.00 0.02 0.01 0.01 0.02
## TMEM38A 4.24 3.51 3.35 3.93 4.73 3.57 4.03
## AP1M1 22.26 21.55 21.22 19.93 22.77 21.27 20.83
## PVR 22.61 19.79 21.43 24.64 28.98 27.39 28.41
## IKBKG 14.86 16.79 14.95 30.29 21.02 21.04 21.62
## XRCC1 20.86 19.40 19.71 13.95 16.81 14.20 17.22
## SCARB1 66.64 65.75 67.70 81.66 66.86 74.29 70.21
## CYP2W1 0.68 0.83 0.91 0.26 0.35 0.39 0.35
## MCM2 36.63 33.20 32.76 25.55 37.68 33.11 40.29
## MOV10L1 0.15 0.14 0.09 0.16 0.21 0.17 0.19
## PANX2 1.16 1.60 1.50 5.08 3.73 3.74 3.53
## SELO 12.64 14.06 14.48 19.26 15.80 13.66 15.23
## TP63 0.15 0.16 0.16 0.03 0.05 0.12 0.02
## ALPK1 8.07 8.24 8.96 11.64 8.04 11.10 8.20
## LLGL2 97.28 110.64 107.13 128.72 119.35 109.26 120.24
## PDE8A 5.45 5.11 5.48 6.22 5.12 5.31 5.73
## CLCN4 0.47 0.22 0.28 0.42 0.35 0.61 0.39
## NLE1 20.32 14.03 16.08 12.01 14.79 18.34 15.85
## SDHA 177.65 173.73 165.91 155.15 169.09 143.64 162.28
## SMARCE1 221.76 202.93 209.72 158.18 187.02 176.71 198.94
## FNDC8 0.10 0.13 0.07 0.00 0.06 0.09 0.09
## GSDMB 10.82 18.70 15.19 11.76 7.86 8.41 9.04
## KDM5A 8.96 6.38 7.48 7.73 7.27 9.34 10.62
## ADAM11 1.70 1.83 2.22 2.59 1.74 2.66 2.52
## PPP2R3A 4.96 4.20 4.01 5.37 5.05 5.10 5.44
## FERMT2 21.38 19.42 18.63 28.49 29.04 27.24 29.34
## ABCB11 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DHRS9 0.04 0.00 0.00 0.07 0.03 0.04 0.06
## CD5L 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PTGS2 0.00 0.00 0.00 0.01 0.04 0.01 0.00
## IGF2BP2 0.53 0.67 0.44 0.30 0.62 0.52 0.60
## MAP3K13 69.17 72.16 71.64 63.25 63.91 68.66 70.07
## ST6GAL1 30.35 25.72 25.59 14.63 13.65 16.14 14.32
## TBX21 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## FRY 0.81 0.64 0.73 0.61 0.61 0.72 0.27
## PICALM 95.09 89.94 84.15 141.44 116.98 127.93 121.77
## NSF 49.55 41.36 39.95 46.54 51.75 51.82 56.18
## GLI2 0.00 0.01 0.11 0.02 0.00 0.01 0.06
## CLASP1 5.00 5.11 5.33 5.23 4.53 6.24 5.53
## MRPS34 155.80 150.64 145.08 112.99 144.17 125.57 142.41
## NOTCH3 22.94 21.47 21.55 18.46 21.89 19.07 22.70
## CLNS1A 182.44 175.77 171.84 136.95 154.62 162.79 154.05
## PPP2R2C 7.77 6.59 6.74 11.97 12.60 11.35 14.08
## TEAD2 13.79 13.57 11.04 10.88 12.36 10.73 12.87
## EED 31.02 32.10 31.87 37.08 35.71 32.71 35.09
## CDHR2 0.23 0.02 0.17 0.24 0.09 0.08 0.06
## SNCB 6.34 6.51 8.63 6.11 5.30 5.48 4.37
## TSG101 75.96 64.25 59.82 62.05 75.97 73.08 79.48
## C17orf85 22.65 17.06 20.43 19.69 20.47 20.63 20.64
## ATP2A3 26.41 28.57 29.62 22.74 20.12 22.66 22.90
## CA12 157.06 182.88 176.57 122.44 147.36 153.54 177.41
## MGLL 7.34 6.74 7.21 5.08 6.23 6.24 6.12
## NTN4 3.64 3.71 3.67 3.26 2.52 3.61 2.04
## BCS1L 31.62 32.27 33.92 42.72 39.03 43.59 39.81
## NUAK1 0.71 0.67 0.78 0.36 0.59 0.50 0.55
## DPP8 15.78 11.57 13.07 12.28 14.73 13.33 16.56
## SLC24A1 10.38 10.99 11.86 9.05 7.93 14.49 11.12
## ZNF532 22.95 17.39 20.30 19.38 13.81 18.22 17.96
## SCARF1 1.28 1.23 1.24 3.29 1.04 2.21 1.26
## LMAN1 45.38 43.78 43.44 38.46 41.61 46.47 47.00
## PTPLAD1 90.93 83.93 79.79 63.43 86.54 84.59 88.93
## IPCEF1 0.00 0.00 0.00 0.01 0.00 0.00 0.06
## ZZEF1 6.66 6.35 6.83 8.50 7.14 7.42 7.74
## NOX3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ENO1 1008.94 766.37 920.21 900.26 993.58 904.27 923.76
## SLC12A1 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## C19orf10 113.32 110.93 110.07 127.15 129.18 127.81 131.05
## ANO8 7.21 7.75 7.53 11.86 7.21 8.51 8.56
## TUBE1 7.88 6.22 6.44 14.60 9.81 11.48 10.50
## ARHGEF10L 11.66 11.76 11.72 12.43 9.92 14.40 11.66
## TXK 0.00 0.01 0.04 0.13 0.04 0.02 0.21
## WSCD2 0.00 0.00 0.00 0.00 0.00 0.00 0.06
## KCNQ2 0.23 0.03 0.06 0.02 0.00 0.05 0.09
## TACR2 0.40 0.30 0.32 0.15 0.28 0.19 0.33
## ACTR6 47.12 48.02 43.05 48.94 49.73 48.71 52.45
## TIPIN 16.49 17.10 17.94 19.70 21.61 21.87 21.98
## SRI 53.47 39.40 43.43 47.42 46.70 50.92 47.57
## EIF4G3 15.36 14.57 14.48 16.66 14.22 15.60 16.34
## NUP37 73.12 61.80 60.87 53.60 73.81 66.12 68.80
## SEMA3A 0.46 0.64 0.62 0.05 0.24 0.29 0.46
## GTSE1 11.42 15.91 13.14 10.77 12.18 10.69 11.88
## SEMA3C 133.87 111.62 109.92 72.38 121.48 103.88 133.26
## TTC38 21.47 18.26 18.53 22.91 20.51 22.07 22.73
## ACAT1 91.42 96.52 94.38 140.75 114.11 141.56 114.80
## GRAMD4 11.69 12.43 12.00 10.65 10.03 10.94 11.21
## CELSR1 45.37 54.08 49.19 38.64 41.91 35.90 44.29
## WNT8B 0.54 0.66 0.47 0.12 0.23 0.24 0.25
## ZNF638 50.40 55.08 48.68 43.54 42.63 42.82 44.63
## SLC25A40 13.02 12.54 10.49 15.98 15.82 14.43 16.60
## TIMM21 25.02 26.36 24.38 27.61 26.14 25.30 26.32
## ADD2 0.01 0.11 0.02 0.04 0.02 0.01 0.04
## FGF4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RASAL2 5.45 4.78 4.51 3.76 4.75 5.28 5.35
## VPS9D1 20.30 22.35 22.08 28.14 20.38 19.85 20.70
## ZNF37A 10.89 11.18 11.40 8.35 8.29 10.23 8.49
## MARK3 64.00 66.95 62.51 63.91 65.62 60.25 68.12
## SLC25A3 627.24 588.74 572.29 652.17 683.49 640.02 659.08
## FNDC3B 19.16 13.50 16.43 21.45 22.27 26.71 24.04
## FOSL2 4.60 3.05 4.49 5.99 6.19 5.81 6.01
## CACNG5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CACNG4 41.16 38.89 36.48 41.80 51.44 38.36 48.00
## FRYL 10.20 10.08 8.92 10.71 10.22 10.10 10.59
## TMEM131 11.38 9.43 8.47 11.37 10.96 11.58 11.69
## FSCN1 2.38 1.13 1.47 1.03 0.98 1.44 1.23
## ACTB 3104.21 3164.36 3226.88 2480.70 2924.86 2677.90 2889.24
## MOCOS 1.96 1.50 1.39 2.11 2.16 2.13 2.50
## PLD1 9.85 9.45 8.36 14.00 9.63 11.67 11.09
## ATP12A 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## WDR62 5.21 6.26 5.43 11.23 9.19 8.30 8.68
## DLG1 100.55 98.68 88.25 105.45 99.98 105.67 119.47
## RAB7A 206.39 194.78 194.91 330.00 253.16 300.43 268.41
## BCAP29 27.71 24.33 26.27 22.22 31.02 24.67 29.77
## SEC31B 8.60 10.30 9.33 7.08 5.62 6.77 7.30
## SART3 35.87 33.75 31.98 41.36 35.40 38.08 37.41
## ARHGAP15 6.18 6.27 7.49 1.37 3.48 3.39 2.75
## TUBA3D 0.05 0.14 0.00 0.10 0.34 0.02 0.06
## PAX2 0.24 0.20 0.20 0.11 0.14 0.18 0.17
## EXOSC7 54.47 52.95 54.59 56.63 58.33 54.78 57.27
## KIFAP3 19.61 22.22 21.00 16.85 19.80 22.27 21.18
## MKRN2 29.21 28.81 28.54 38.89 32.20 35.11 33.80
## MCM6 26.81 24.49 25.40 21.49 32.12 24.71 31.64
## REXO2 123.73 112.62 118.21 154.61 139.80 145.34 148.97
## RBM7 17.34 13.78 14.14 16.36 18.25 21.07 19.36
## RBMS2 6.40 5.02 5.47 3.73 4.28 5.79 5.34
## BAZ2A 42.71 39.68 39.34 43.17 32.75 46.12 43.46
## PTPN23 17.72 16.50 17.75 29.63 21.40 25.02 22.80
## MLH1 49.71 44.43 45.39 46.76 52.53 54.81 53.20
## UNG 68.98 61.52 59.85 38.63 63.04 48.76 62.01
## FMO4 5.52 4.65 4.93 3.87 4.01 5.80 5.32
## KLHL20 12.07 10.48 11.32 12.74 12.20 14.58 13.77
## RGS11 7.27 7.27 7.46 7.52 5.80 8.16 7.99
## SLC46A1 7.94 6.36 7.40 4.47 5.21 6.18 6.25
## PLXNA2 0.41 0.42 0.41 0.28 0.30 0.19 0.26
## SPAG5 33.18 40.57 35.31 32.63 40.48 32.77 39.23
## ANKRD13A 32.61 30.02 32.44 39.70 33.63 40.22 34.46
## TPD52 121.07 101.59 107.81 113.73 121.70 128.00 132.31
## ACACB 1.36 1.38 1.31 1.55 1.29 2.00 1.65
## TRAF4 71.48 82.83 80.65 98.02 73.35 84.99 77.64
## PAG1 1.93 1.66 1.72 2.56 1.73 3.47 2.22
## GPATCH1 6.48 6.24 6.15 6.77 6.06 6.85 6.66
## ICAM3 34.17 33.13 30.52 32.60 32.54 29.03 35.43
## NT5C2 51.80 44.46 43.62 69.00 63.24 72.39 66.45
## MCAM 5.27 4.67 3.84 2.86 4.59 5.64 3.52
## GPC4 0.90 0.82 0.95 0.80 0.83 1.29 0.88
## MBNL3 0.87 0.70 0.77 0.76 0.76 1.09 1.01
## CAMSAP3 21.12 21.69 24.27 15.66 17.47 15.12 20.63
## RAP1GAP 3.45 4.18 4.14 7.81 3.88 6.78 4.33
## XAB2 28.92 29.20 31.83 30.24 30.81 28.92 31.74
## ARHGEF1 31.69 34.80 33.62 34.99 28.41 31.06 32.77
## STXBP2 86.68 88.91 91.56 109.11 92.12 88.52 98.86
## MAP2K7 14.40 14.86 13.75 22.02 15.08 15.13 16.39
## NMRK2 0.00 0.00 0.02 0.00 0.00 0.00 0.00
## DGKD 5.45 6.89 7.61 7.22 5.73 6.42 5.75
## CTTNBP2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ACTL6B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RARB 0.13 0.27 0.21 0.08 0.08 0.12 0.14
## TOP2B 59.54 60.57 58.26 56.57 60.20 57.55 58.47
## TM9SF3 122.40 93.26 96.76 97.47 109.52 124.37 126.93
## NFKB2 34.34 39.61 38.99 43.82 39.33 40.30 38.74
## UBE2T 91.21 109.38 94.64 89.65 118.59 95.19 105.76
## PPP1R12B 4.31 4.37 3.89 5.76 4.32 6.76 4.77
## DNAJC10 40.11 36.11 34.70 40.48 37.02 48.24 38.48
## GTF3C1 49.58 55.12 54.10 52.97 57.95 49.08 52.41
## IL4R 6.52 5.83 5.08 2.50 5.26 3.11 3.95
## USP33 19.23 16.31 15.83 19.87 19.71 20.77 19.64
## PAK3 0.00 0.00 0.00 0.00 0.00 0.00 0.04
## CAPN6 0.02 0.00 0.00 0.00 0.00 0.03 0.01
## DCX 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SNRPA 71.35 88.23 87.41 72.62 67.17 72.58 68.85
## SPAG6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## EXOSC5 17.95 17.15 19.42 14.39 16.77 17.99 18.19
## DYNC1I2 58.05 51.00 50.63 57.94 64.45 64.46 64.25
## APBB1IP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## LRCH4 30.99 35.93 33.81 40.74 30.54 29.90 33.03
## FAM76B 24.13 25.82 23.48 28.32 24.84 25.28 26.17
## SIRT6 14.77 15.00 15.28 27.54 17.59 17.79 18.68
## TYR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## POLD3 15.62 14.81 14.01 12.17 15.32 13.96 15.30
## ACTN2 1.57 1.02 1.50 0.56 0.39 0.94 0.45
## CAPZB 170.81 166.55 162.99 150.73 167.83 149.79 169.52
## GPR137B 32.37 29.86 31.13 35.98 29.38 38.16 32.73
## NAALAD2 0.31 0.29 0.25 0.64 0.41 0.35 0.38
## JADE1 7.32 7.49 6.85 7.47 7.83 7.76 7.27
## SLC25A43 6.20 6.04 6.26 4.58 6.29 5.50 7.04
## UBE2A 64.94 59.53 56.39 69.28 77.09 70.18 76.67
## FGFR1 18.53 17.37 16.55 21.48 19.19 20.59 20.59
## FKBP6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GTF2I 113.14 115.33 105.66 68.25 79.11 75.76 83.78
## SMC1B 0.17 0.20 0.21 0.08 0.08 0.09 0.10
## FBLN1 1.30 0.81 1.43 1.23 1.12 0.86 1.40
## ITGA8 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CST7 0.30 0.12 0.03 0.65 0.14 0.34 0.28
## MAP2 3.81 3.13 4.22 6.52 3.70 5.98 4.78
## PIAS2 8.99 6.24 7.69 10.43 9.75 9.62 9.73
## AMPH 0.23 0.14 0.12 0.12 0.09 0.09 0.29
## ARAF 73.14 81.21 77.88 59.55 65.31 69.48 68.36
## MCCC1 98.62 103.63 100.15 121.55 106.72 114.56 109.58
## LAMP3 4.98 3.91 4.19 8.49 8.30 8.89 7.36
## FAP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NEBL 22.55 16.19 18.94 22.01 18.50 26.58 21.90
## ACER3 19.83 17.92 19.74 21.66 26.35 25.35 26.70
## UBE2K 52.37 48.18 45.65 47.16 54.95 51.94 54.41
## PIK3C3 26.32 21.22 22.19 19.80 25.02 24.37 23.83
## N4BP2 2.26 1.89 1.97 1.93 1.93 2.68 2.36
## C12orf5 3.86 2.60 2.90 2.60 4.74 2.87 4.14
## TULP3 20.08 18.51 18.56 25.16 20.66 22.24 21.89
## SYNJ2 6.13 6.17 6.10 4.38 4.46 5.38 5.49
## ADCY2 0.19 0.33 0.08 0.02 0.09 0.03 0.09
## PPP2R5C 143.68 131.61 133.30 135.69 153.62 141.97 150.37
## RBFOX1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GNB1 163.46 133.52 131.81 135.71 160.79 142.95 155.39
## HOXA9 0.00 0.00 0.02 0.00 0.00 0.00 0.00
## EDN1 79.66 88.26 85.07 71.97 66.57 75.07 76.92
## MLLT10 10.30 7.81 8.32 15.42 11.08 14.20 13.56
## ZCWPW1 4.68 5.04 3.87 6.46 4.94 4.94 5.05
## ADCYAP1R1 0.00 0.00 0.05 0.00 0.00 0.00 0.00
## FGF20 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## P2RY10 0.30 0.20 0.38 0.55 0.26 0.11 0.45
## ITM2A 4.09 3.17 3.45 2.62 3.84 3.06 2.61
## NRD1 67.54 73.88 67.04 93.30 80.05 74.84 83.29
## VDAC3 244.69 227.50 217.13 231.03 271.95 253.67 262.23
## PCM1 61.81 64.54 57.87 64.34 58.81 63.22 63.94
## TNRC6C 3.87 3.40 3.41 4.16 3.42 4.48 4.36
## CBFA2T2 8.78 9.23 8.69 21.63 10.45 12.84 12.11
## BRINP1 0.02 0.00 0.05 0.01 0.02 0.02 0.02
## ITCH 25.68 17.70 20.33 22.59 24.11 27.76 25.11
## PKD2L2 0.00 0.01 0.00 0.03 0.03 0.00 0.03
## TP53INP2 33.47 22.40 24.40 33.27 27.66 27.02 31.07
## SDF4 121.51 132.65 130.59 131.63 119.51 121.61 123.02
## MYH7B 0.64 0.46 0.71 0.35 0.26 0.46 0.39
## BPIFB2 0.15 0.09 0.24 0.02 0.02 0.12 0.07
## TP73 5.07 4.78 4.62 2.75 3.93 3.01 3.75
## TOLLIP 26.97 22.64 24.11 39.76 32.18 36.44 31.08
## UBE2D4 10.35 9.42 9.24 14.93 11.04 12.71 11.16
## CLUL1 0.40 1.02 0.54 0.67 0.28 0.71 0.92
## RUNX1T1 0.14 0.01 0.08 0.00 0.05 0.08 0.23
## CDH17 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## THOC1 19.93 23.20 22.08 23.86 20.18 19.54 23.27
## FKBP7 2.23 1.29 2.07 1.52 1.39 1.48 1.90
## OSBPL6 1.83 1.36 1.48 2.58 1.92 2.00 2.30
## SLC1A3 0.19 0.09 0.12 0.13 0.12 0.40 0.17
## XRCC5 139.71 123.81 122.87 114.79 142.26 128.32 145.08
## LXN 0.06 0.00 0.05 0.00 0.00 0.00 0.07
## SP140 0.39 0.76 0.79 0.60 0.37 0.56 0.85
## MKNK1 21.99 19.98 21.09 32.11 23.49 27.90 27.32
## TNS1 0.32 0.41 0.58 0.29 0.38 0.95 0.38
## REXO1 12.25 11.56 10.86 15.66 10.79 10.35 11.66
## SAR1A 48.35 46.51 44.45 47.04 49.82 49.91 51.34
## CDC14A 1.68 1.45 1.39 1.66 1.90 1.50 2.13
## RAPGEF3 21.09 31.96 24.65 23.81 17.33 19.39 19.61
## CEACAM1 1.40 1.25 1.30 1.46 0.97 1.73 1.36
## SENP1 15.90 12.11 11.61 12.91 15.27 16.00 15.51
## DUSP13 0.73 2.15 1.69 5.68 3.28 3.52 3.06
## CIC 17.63 14.42 14.85 21.25 15.88 15.45 17.48
## LIPE 0.65 1.17 1.20 0.98 0.48 0.39 0.78
## FDFT1 155.81 166.71 153.78 185.66 208.04 158.88 211.63
## PAFAH1B3 85.73 93.65 91.26 91.87 92.91 84.17 91.56
## OPHN1 2.72 2.42 2.23 2.64 2.49 3.14 2.64
## AFM 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## KIF22 68.12 81.04 74.09 79.10 83.88 73.68 77.89
## SCGN 0.00 0.06 0.04 0.00 0.00 0.00 0.02
## LRRC16A 5.94 6.28 5.63 5.48 6.53 5.95 6.86
## PGM1 16.48 11.87 15.07 12.65 15.13 14.20 15.16
## DDX1 54.44 55.59 53.19 47.99 56.07 53.04 58.72
## DNM2 61.66 65.09 66.25 79.61 71.06 64.58 71.08
## EPB41L2 3.03 2.60 3.80 3.09 2.96 5.02 3.99
## RIMS1 0.95 0.69 0.67 0.36 0.55 0.77 0.51
## MOXD1 0.00 0.00 0.00 0.01 0.00 0.07 0.01
## STX7 21.03 14.18 15.22 22.98 21.05 25.70 21.84
## RABL2B 16.53 20.29 18.86 12.44 15.95 16.54 14.56
## KEAP1 50.49 51.84 46.67 67.68 54.83 60.60 52.73
## DDX43 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PTPRH 1.14 0.48 0.82 0.65 0.58 1.10 0.80
## DCT 0.00 0.00 0.00 0.00 0.02 0.00 0.00
## SLC35C2 67.41 69.29 66.80 67.40 63.47 66.72 67.48
## CRYBG3 8.45 6.75 7.25 8.21 7.85 7.84 8.93
## EPHA6 0.17 0.03 0.02 0.06 0.09 0.09 0.06
## SCTR 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## RFX3 1.50 1.36 1.01 1.01 1.13 1.15 1.05
## RIF1 5.52 5.51 4.98 5.14 5.13 5.33 5.23
## RAB21 55.01 48.94 50.67 71.91 61.57 63.31 67.34
## SLC4A4 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## SMARCA2 27.69 29.79 25.84 20.62 22.89 25.75 24.39
## RDH8 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SESN1 5.10 5.64 5.12 5.01 4.77 5.05 4.69
## MID2 3.26 2.29 2.99 3.18 3.99 4.02 3.79
## PIH1D3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## COL5A3 0.01 0.01 0.00 0.01 0.01 0.00 0.01
## SRCAP 22.17 18.18 18.52 24.22 20.03 22.82 23.28
## KIAA0020 15.01 14.39 17.18 17.53 18.64 19.28 17.61
## CPB2 0.05 0.15 0.04 0.04 0.04 0.09 0.03
## CHRNA3 0.65 0.49 0.51 0.28 0.33 0.32 0.23
## KCNN2 0.46 0.51 0.37 0.10 0.22 0.18 0.17
## CNOT4 9.60 8.50 8.80 8.42 8.91 8.38 9.41
## PSEN1 57.42 48.03 49.81 64.18 64.25 63.83 65.95
## CPOX 10.09 9.67 8.95 8.73 9.95 10.02 10.10
## CLDND1 34.54 33.02 31.80 34.38 29.62 34.75 34.65
## MOK 26.65 26.21 27.25 19.60 21.10 22.90 23.55
## HSP90AA1 656.15 593.41 564.91 1317.04 815.74 716.22 847.05
## RBL1 4.84 4.45 4.82 5.49 6.32 5.65 7.41
## DLGAP4 52.63 44.52 48.53 59.61 46.16 53.34 49.24
## IGSF9B 0.19 0.40 0.39 0.22 0.22 0.36 0.23
## CFHR2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NDC80 15.09 20.58 17.82 14.25 19.69 15.44 17.50
## AP4E1 5.27 4.61 4.43 4.90 5.40 5.17 5.89
## RSBN1 3.47 2.90 3.79 4.10 4.03 4.10 4.39
## MAGI3 7.16 6.40 6.63 6.83 5.60 7.26 6.86
## CXCL2 0.57 0.47 0.24 0.03 0.22 0.21 0.02
## AFP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## COL4A4 0.00 0.02 0.02 0.03 0.02 0.02 0.02
## TCF7 2.02 1.26 1.75 1.58 1.65 1.08 1.44
## OSTM1 16.82 12.38 13.45 28.81 27.70 26.38 22.89
## CDH7 0.41 0.27 0.32 0.05 0.11 0.15 0.33
## IMPG2 0.03 0.00 0.05 0.01 0.03 0.01 0.03
## PCNP 101.41 87.01 87.82 98.47 111.08 98.23 102.56
## EXD2 24.49 20.60 20.04 18.97 20.54 20.81 21.36
## ARG2 14.67 12.01 10.78 5.59 9.49 7.29 9.66
## MEF2C 0.02 0.12 0.16 0.03 0.06 0.01 0.02
## PTPRC 0.01 0.09 0.01 0.02 0.00 0.00 0.01
## CACNA1S 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## PKP1 0.02 0.05 0.01 0.01 0.02 0.01 0.01
## UBA5 28.34 29.34 30.38 27.76 30.50 30.41 30.64
## STK17B 3.60 2.85 3.12 4.05 3.72 5.17 3.97
## CDC14B 2.14 1.54 1.77 1.75 1.63 1.95 1.55
## ZNF510 4.66 4.05 4.47 4.42 4.45 4.89 5.04
## LRP2 0.02 0.02 0.01 0.02 0.01 0.01 0.13
## ZNF506 11.30 8.45 10.71 8.24 7.01 8.65 8.77
## JMJD4 25.46 21.15 24.11 17.83 23.45 22.44 22.64
## DUSP12 32.27 30.26 32.11 32.62 35.16 38.89 34.38
## AACS 26.99 23.89 23.80 21.64 24.47 26.94 24.78
## KIAA0141 115.02 112.39 113.05 91.93 94.83 103.15 96.88
## SLC13A1 0.00 0.00 0.00 0.00 0.00 0.01 0.01
## CADPS2 4.95 4.95 4.28 3.30 4.16 2.77 4.28
## PCDHB4 0.31 0.37 0.42 0.45 0.33 0.38 0.45
## PCDHA6 0.22 0.36 0.38 0.20 0.22 0.22 0.28
## PCDHGA2 0.57 0.36 0.59 0.50 0.29 0.31 0.41
## HSPB11 116.36 104.43 98.79 172.33 160.39 177.83 159.29
## PHLPP1 2.65 2.26 2.54 2.61 2.17 3.54 2.63
## ATP8B1 12.34 10.26 11.17 13.84 11.36 15.21 13.33
## IL12RB2 0.03 0.01 0.04 0.02 0.01 0.02 0.05
## SMARCD3 12.44 14.09 13.87 11.01 10.38 10.08 10.54
## WDR70 26.06 28.00 23.49 19.21 22.79 18.63 21.01
## FYB 0.06 0.00 0.00 0.00 0.00 0.00 0.00
## MPP4 0.03 0.06 0.03 0.06 0.00 0.07 0.05
## STRADB 8.10 10.51 8.57 11.63 11.62 11.67 10.60
## BZW1 80.41 62.96 66.67 61.22 82.66 72.00 80.08
## PGR 75.34 63.82 61.85 40.08 69.19 58.02 77.34
## C1QTNF3 1.84 5.10 3.17 1.32 1.16 0.90 1.80
## ME2 9.11 9.11 9.69 13.61 13.86 14.12 13.19
## C5orf22 26.40 22.57 25.29 28.98 27.27 29.64 29.23
## CCNT2 9.63 10.05 9.87 14.22 11.26 11.32 10.89
## FAM135A 1.33 1.52 1.13 2.09 1.60 1.89 1.78
## COL19A1 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## EPB41L3 3.53 3.06 2.67 2.35 2.65 2.54 3.71
## COBLL1 9.47 7.55 7.91 11.73 10.25 12.49 10.50
## DLG3 22.40 15.98 18.51 15.01 16.68 19.39 18.40
## KCNK2 76.72 58.57 61.58 31.81 58.72 50.44 60.75
## SERTAD4 22.51 20.90 17.26 10.57 19.56 14.74 19.07
## TRAF5 7.31 9.09 8.31 12.32 7.19 9.99 8.05
## MRPL22 148.13 143.35 132.97 135.19 157.83 129.52 146.00
## GEMIN5 11.63 9.23 10.79 9.97 12.08 11.57 12.79
## OPRK1 0.00 0.00 0.00 0.00 0.03 0.00 0.00
## NFE2L1 119.85 90.79 102.99 156.41 126.56 179.47 141.09
## SEMA5B 0.00 0.00 0.04 0.00 0.00 0.06 0.00
## GSK3B 27.53 19.67 22.46 27.05 26.80 30.73 26.14
## ITGB5 77.19 71.74 58.48 69.89 64.67 64.11 63.85
## ERC1 7.46 5.87 6.12 5.50 6.42 6.83 7.01
## XPO1 75.44 71.88 70.01 99.14 77.67 94.88 81.69
## C4orf6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RNF13 91.21 81.81 82.65 94.99 89.15 103.21 87.41
## TRPM3 0.01 0.01 0.00 0.00 0.00 0.00 0.00
## PALB2 12.67 9.82 12.15 16.61 16.24 15.16 14.10
## DOPEY1 2.86 3.05 3.51 3.68 3.27 3.85 3.56
## LYRM2 35.43 33.54 31.97 43.20 43.87 44.08 41.52
## BCKDHB 16.68 12.63 12.57 11.74 14.75 14.73 15.07
## mRNA_R31 mRNA_R35 mRNA_R34 mRNA_R33 mRNA_R32 mRNA_R30 mRNA_R29
## TSPAN6 19.42 19.69 18.56 17.74 16.08 18.37 17.42
## TNMD 0.00 0.04 0.00 0.00 0.00 0.00 0.00
## DPM1 118.91 124.45 124.31 110.52 134.33 107.29 134.78
## SCYL3 2.92 3.78 3.34 2.53 3.27 3.66 2.96
## C1orf112 4.11 4.16 6.52 4.97 4.38 3.99 2.83
## FGR 0.28 0.30 0.32 0.20 0.57 0.24 0.72
## CFH 4.01 5.14 4.84 4.56 4.85 4.62 5.38
## FUCA2 69.66 75.77 82.49 71.80 83.97 76.41 79.45
## GCLC 25.22 40.47 33.50 42.71 54.53 64.56 47.87
## NFYA 6.04 8.91 8.58 7.49 7.08 8.82 9.29
## STPG1 5.31 5.52 5.48 5.09 5.99 6.60 7.43
## NIPAL3 11.84 16.33 11.18 12.38 11.62 15.79 14.48
## LAS1L 24.56 31.04 26.35 27.27 31.29 26.42 33.04
## ENPP4 3.11 5.54 5.86 3.52 4.61 4.39 3.33
## SEMA3F 0.65 0.90 0.26 0.65 0.94 0.51 0.88
## CFTR 0.03 0.15 0.03 0.01 0.08 0.15 0.05
## ANKIB1 13.73 21.23 17.06 14.26 14.88 19.89 16.62
## CYP51A1 41.18 47.57 32.64 45.37 58.63 53.83 50.20
## KRIT1 13.58 20.07 19.66 12.37 12.57 16.28 13.99
## RAD52 6.93 10.26 6.90 8.63 7.77 5.82 10.15
## BAD 100.08 74.96 97.64 94.40 63.67 75.52 61.78
## LAP3 46.33 55.25 53.33 48.86 80.31 53.96 66.07
## CD99 123.62 122.60 106.72 114.08 112.23 113.58 117.24
## HS3ST1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## AOC1 0.00 0.08 0.00 0.00 0.07 0.00 0.07
## WNT16 0.03 0.04 0.07 0.08 0.09 0.03 0.05
## HECW1 7.56 8.46 6.23 4.91 6.59 6.17 6.59
## MAD1L1 17.86 17.27 17.23 21.88 14.52 13.05 12.47
## LASP1 90.47 105.09 79.41 99.97 86.24 100.84 82.82
## SNX11 28.17 25.63 26.83 26.31 26.99 31.56 28.02
## TMEM176A 0.05 0.05 0.11 0.04 0.00 0.00 0.00
## M6PR 83.05 89.54 104.07 99.50 134.14 118.33 110.13
## KLHL13 1.69 2.62 2.88 1.38 1.43 1.53 1.60
## CYP26B1 19.01 34.16 13.24 17.04 6.45 14.38 10.47
## ICA1 0.08 0.13 0.23 0.04 0.07 0.09 0.04
## DBNDD1 1.89 1.76 1.89 2.41 0.90 1.19 1.05
## ALS2 12.67 16.58 16.16 13.74 19.21 19.52 20.03
## CASP10 3.74 4.82 3.49 2.70 2.15 2.90 4.31
## CFLAR 54.84 58.31 58.19 48.25 44.39 49.63 65.08
## TFPI 190.92 214.00 192.41 161.40 138.36 190.34 147.47
## NDUFAF7 15.93 23.85 20.42 23.70 19.25 20.26 16.62
## RBM5 31.22 49.47 42.65 38.33 41.15 45.04 36.34
## MTMR7 1.78 2.47 2.10 3.05 2.92 3.02 2.59
## SLC7A2 0.01 0.02 0.01 0.00 0.01 0.00 0.03
## ARF5 222.57 188.15 191.09 199.90 187.95 179.66 203.20
## SARM1 5.15 6.75 7.86 7.26 6.88 6.01 6.56
## POLDIP2 128.82 120.23 128.27 141.97 141.14 146.25 134.75
## PLXND1 20.15 30.34 14.31 22.49 17.35 20.67 20.95
## AK2 209.01 194.98 271.23 226.02 208.94 209.38 172.25
## CD38 0.79 0.85 0.65 0.40 0.42 0.31 0.67
## FKBP4 132.16 133.89 141.63 167.42 149.92 162.34 111.65
## KDM1A 36.19 46.17 38.17 42.51 39.29 41.72 34.80
## RBM6 22.04 31.92 25.53 29.38 26.37 29.05 27.11
## CAMKK1 17.56 19.45 18.32 17.59 13.65 13.48 13.85
## RECQL 26.93 39.44 45.32 39.38 37.49 37.52 28.13
## CCDC132 8.63 11.88 11.10 10.24 9.88 10.75 9.45
## HSPB6 15.98 20.30 10.90 15.10 16.82 14.78 22.35
## ARHGAP33 2.63 5.90 4.05 4.57 4.10 3.50 6.38
## NDUFAB1 144.38 114.08 155.70 134.48 140.03 131.21 129.83
## PDK4 4.83 8.74 1.27 1.87 1.73 2.53 2.93
## SLC22A16 0.00 0.14 0.00 0.09 0.02 0.11 0.03
## ZMYND10 2.09 1.52 3.41 1.85 0.99 1.34 0.84
## ABCB5 0.00 0.00 0.07 0.02 0.00 0.00 0.02
## ARX 0.00 0.02 0.00 0.01 0.01 0.03 0.00
## SLC25A13 10.14 12.24 12.55 13.06 14.19 13.83 11.25
## ST7 17.91 20.62 17.34 18.21 15.75 18.60 15.97
## CDC27 36.05 43.78 48.36 42.73 36.15 44.12 28.38
## SLC4A1 0.03 0.12 0.06 0.14 0.08 0.23 0.03
## CALCR 0.11 0.07 0.04 0.04 0.01 0.02 0.04
## HCCS 50.81 49.17 51.41 52.70 63.07 64.29 54.00
## DVL2 20.63 25.20 23.72 24.52 26.45 24.67 29.22
## PRSS22 2.99 3.13 2.47 0.91 1.34 1.07 2.02
## UPF1 28.48 34.20 27.51 39.65 37.11 36.66 31.38
## SKAP2 12.32 19.30 17.74 10.95 10.46 15.87 11.78
## SLC25A5 299.78 260.32 318.05 304.56 298.63 312.56 268.67
## CCDC109B 25.46 24.53 24.97 22.82 21.78 23.90 22.09
## HOXA11 0.72 1.13 0.74 0.67 0.86 0.57 1.31
## POLR2J 122.16 93.69 128.35 101.38 107.44 91.33 99.76
## DHX33 8.47 10.43 9.68 9.09 11.08 12.31 11.19
## MEOX1 0.56 0.80 0.57 0.46 0.04 0.14 0.06
## THSD7A 0.22 0.17 0.16 0.02 0.08 0.01 0.00
## LIG3 4.92 9.00 6.18 5.95 5.55 7.13 7.32
## RPAP3 21.76 27.64 26.93 25.24 30.15 29.99 23.02
## ACSM3 2.61 4.25 1.56 1.75 3.74 2.94 4.20
## AC004381.6 6.46 8.57 9.11 7.44 7.90 6.23 9.42
## CIAPIN1 59.14 53.42 57.73 64.29 62.20 63.08 59.75
## FAM214B 29.74 38.16 28.85 34.48 35.68 43.19 34.06
## COPZ2 158.91 133.57 131.20 114.09 120.50 103.72 144.64
## PRKAR2B 0.55 1.17 1.24 0.75 0.90 0.85 1.02
## MSL3 21.01 27.29 21.10 20.87 18.39 20.78 17.29
## CREBBP 2.77 5.34 4.49 4.23 3.88 6.32 4.18
## BZRAP1 0.35 0.72 0.30 0.22 0.30 0.27 0.63
## MPO 0.01 0.13 0.01 0.03 0.00 0.00 0.01
## PON1 0.00 0.00 0.09 0.00 0.00 0.00 0.15
## GCFC2 15.74 14.64 18.24 14.68 15.10 17.34 17.86
## WDR54 74.03 63.33 86.42 69.05 51.77 55.82 51.23
## CROT 12.72 15.59 15.68 13.81 15.22 14.20 12.61
## ABCB4 0.34 0.50 0.16 0.15 0.50 0.34 0.15
## KMT2E 11.75 18.55 15.32 11.62 11.73 17.50 15.03
## RHBDD2 78.44 72.58 64.29 66.99 80.92 72.37 90.68
## SOX8 0.01 0.01 0.03 0.01 0.01 0.00 0.02
## IBTK 10.49 15.27 12.83 12.24 14.62 15.77 12.97
## ZNF195 9.48 14.33 12.95 12.69 15.97 14.73 14.74
## MYCBP2 13.51 22.87 18.02 18.01 13.45 20.57 13.16
## FBXL3 33.58 44.26 43.25 39.83 39.54 43.94 36.18
## ITGAL 0.45 0.26 0.50 0.60 0.39 0.45 1.01
## PDK2 12.98 12.31 11.29 9.95 11.00 8.58 10.18
## ITGA3 289.54 331.55 280.31 367.49 251.45 289.55 257.48
## ZFX 3.50 7.76 6.43 5.03 5.42 7.29 5.67
## LAMP2 51.75 73.90 65.29 54.92 71.62 86.49 73.55
## GGNBP2 38.09 52.72 50.73 45.83 51.54 42.65 49.58
## ITGA2B 0.18 0.43 0.13 0.38 0.15 0.72 0.19
## ASB4 0.08 0.06 0.01 0.01 0.03 0.02 0.02
## GDE1 45.55 55.19 47.53 51.50 43.82 52.90 45.23
## C19orf60 83.20 62.69 77.39 68.07 76.39 53.45 84.74
## CRLF1 2.12 1.96 2.82 3.88 3.47 2.69 1.91
## OSBPL7 4.74 6.81 6.37 4.94 4.22 2.54 4.60
## TMEM98 22.49 21.53 29.94 26.56 22.23 22.68 18.00
## YBX2 0.10 0.07 0.03 0.15 0.18 0.14 0.12
## KRT33A 0.05 0.04 0.03 0.10 0.09 0.09 0.14
## ABCC8 0.00 0.00 0.06 0.00 0.07 0.00 0.00
## CCL18 0.14 0.09 0.06 0.05 0.57 0.03 0.65
## CCL3 22.55 15.84 10.48 12.74 18.12 15.48 16.55
## SYNRG 7.93 13.00 9.51 8.44 9.84 12.01 12.61
## CACNG3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMEM132A 530.61 555.49 506.53 577.74 410.01 432.58 448.78
## AP2B1 58.83 77.63 63.09 63.33 61.62 74.60 63.37
## TAC1 0.06 0.03 0.00 0.00 0.00 0.00 0.07
## ZNF263 13.21 16.24 12.77 13.55 17.14 16.41 17.26
## CX3CL1 0.21 0.17 0.01 0.06 0.03 0.08 0.09
## SPATA20 18.83 21.83 20.99 21.57 19.80 18.00 22.67
## CACNA1G 0.29 0.51 0.26 0.52 0.55 0.40 0.88
## TNFRSF12A 382.28 285.69 339.33 306.89 291.28 297.44 319.10
## DLX6 0.13 0.13 0.10 0.06 0.05 0.14 0.11
## MAP3K9 1.57 2.75 1.87 2.43 1.97 3.19 1.64
## RALA 32.71 32.89 29.85 35.68 44.20 44.79 42.27
## BAIAP2L1 0.59 0.91 1.00 1.26 0.60 1.32 0.75
## KDM7A 3.04 6.02 3.33 3.10 3.53 4.76 3.44
## ETV1 8.88 14.59 24.49 11.42 5.36 9.00 5.51
## AGK 32.23 33.64 32.51 32.90 34.72 34.62 34.75
## ALDH3B1 55.79 62.18 36.74 35.14 40.37 37.22 74.94
## TTC22 0.00 0.01 0.00 0.01 0.00 0.01 0.00
## PHTF2 12.50 17.74 16.09 13.79 11.54 15.33 8.09
## CCL26 11.67 8.83 9.32 10.19 12.18 12.26 13.03
## FARP2 10.79 12.96 12.25 10.14 11.45 20.35 15.07
## USH1C 0.52 0.54 0.13 0.17 0.53 0.09 2.24
## GGCT 46.21 44.10 44.80 57.42 66.30 50.69 58.35
## DBF4 12.69 15.21 16.48 15.13 18.13 19.35 15.08
## TBXA2R 3.62 3.81 3.54 5.49 4.30 4.99 3.28
## IFRD1 45.00 42.84 45.83 44.80 55.72 52.84 64.40
## LGALS14 0.00 0.04 0.00 0.05 0.00 0.00 0.28
## COX10 15.99 15.27 13.62 13.44 16.05 17.30 17.38
## GTF2IRD1 17.15 18.96 15.33 21.60 17.18 18.17 11.55
## PAF1 37.13 45.55 40.60 44.07 40.50 38.39 35.74
## VPS41 14.33 22.85 20.17 14.55 21.03 22.31 19.86
## ARHGAP44 0.80 2.18 1.14 0.48 0.34 0.47 0.62
## ELAC2 32.10 39.21 35.80 46.21 43.49 37.25 29.37
## SCIN 0.60 0.74 0.66 0.63 0.61 0.91 0.74
## ARSD 15.36 17.09 10.64 12.44 15.01 12.85 19.39
## PNPLA4 0.00 0.16 0.00 0.06 0.00 0.00 0.00
## MYH13 0.01 0.00 0.01 0.01 0.01 0.00 0.01
## ADIPOR2 28.26 37.36 32.09 33.11 32.06 38.91 30.13
## CDKL3 13.22 12.68 8.30 10.53 10.60 9.43 11.98
## UPP2 0.00 0.01 0.05 0.00 0.04 0.00 0.01
## PRSS21 0.00 0.00 0.05 0.00 0.10 0.05 0.00
## MARK4 16.79 21.48 12.36 17.46 15.13 16.24 15.08
## PROM1 0.12 0.18 0.23 0.08 0.06 0.39 0.22
## CCDC124 158.38 136.42 144.00 179.26 180.31 151.15 145.01
## CEACAM21 0.07 0.07 0.08 0.03 0.04 0.03 0.26
## PAFAH1B1 61.44 83.05 77.70 74.98 76.21 87.45 63.59
## NOS2 0.00 0.02 0.00 0.00 0.00 0.01 0.01
## DNAH9 0.00 0.02 0.00 0.00 0.01 0.03 0.02
## KIAA0100 30.32 47.27 35.48 43.37 31.57 41.37 27.96
## SLC13A2 0.14 0.13 0.09 0.04 0.06 0.05 0.53
## GAS7 0.01 0.02 0.02 0.00 0.00 0.11 0.04
## TRAPPC6A 31.13 28.03 23.07 21.91 29.18 25.50 40.19
## MATK 0.10 0.18 0.13 0.02 0.15 0.00 0.53
## CEACAM7 0.00 0.00 0.00 0.08 0.00 0.00 0.00
## CD79B 1.02 0.13 0.26 0.20 0.17 0.19 0.53
## SCN4A 0.02 0.02 0.03 0.01 0.04 0.03 0.07
## ST7L 32.30 31.59 22.37 23.12 25.84 28.33 34.54
## TKTL1 0.11 0.17 0.00 0.01 0.14 0.06 0.19
## PAX6 11.47 11.62 10.46 9.03 9.00 10.61 9.96
## RPUSD1 14.11 12.24 16.67 23.02 17.63 17.76 12.26
## RHBDF1 11.75 16.42 18.70 19.69 17.63 17.06 13.63
## LUC7L 8.97 12.28 9.08 15.19 13.70 11.63 10.18
## CACNA2D2 0.61 0.93 0.27 0.50 0.38 0.39 0.70
## BAIAP3 0.51 1.05 0.46 0.47 0.40 0.63 0.63
## TSR3 38.06 33.80 36.56 40.67 42.35 34.46 37.36
## PIGQ 8.10 9.61 10.54 9.97 7.65 7.21 7.76
## CRAMP1L 3.22 5.88 3.52 3.85 4.01 4.83 4.10
## TEAD3 5.04 6.75 5.65 6.43 5.39 6.23 6.51
## SELE 0.00 0.01 0.00 0.01 0.01 0.00 0.01
## DNAJC11 32.56 39.27 38.33 41.14 42.25 43.12 37.29
## FMO3 0.16 0.14 0.08 0.06 0.05 0.08 0.07
## MYLIP 1.21 2.10 1.18 1.00 1.52 1.45 2.46
## NOX1 0.24 0.22 0.16 0.37 0.63 0.39 0.37
## E2F2 1.10 1.35 3.09 3.49 1.99 1.61 1.09
## PSMB1 482.36 402.75 389.91 408.13 384.58 401.81 406.96
## SYN1 2.89 4.03 2.52 2.96 2.37 3.08 2.73
## JARID2 5.14 10.25 6.58 5.97 6.69 8.19 5.43
## CDKL5 0.38 0.79 0.58 0.32 0.39 0.72 0.33
## CAMK1G 0.37 0.86 0.13 0.16 0.29 0.10 0.81
## CDK11A 16.39 26.62 20.79 26.99 25.32 24.58 20.06
## NADK 27.03 32.36 33.04 39.19 35.80 35.68 32.30
## TFAP2B 0.11 0.26 0.19 0.26 0.09 0.11 0.16
## TFAP2D 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DLEC1 0.03 0.16 0.23 0.13 0.09 0.11 0.13
## CYTH3 5.38 7.93 6.39 7.49 5.89 9.15 6.05
## ADAM22 1.04 1.74 1.48 1.07 1.53 1.40 1.06
## SYPL1 57.15 76.79 76.26 64.29 91.56 81.56 68.49
## CYB561 20.23 23.14 18.32 16.70 17.24 16.15 20.66
## SPAG9 23.47 39.06 33.02 29.03 30.50 42.25 29.01
## CELSR3 9.46 12.41 8.50 13.67 10.91 12.25 10.43
## AASS 2.89 4.10 2.51 2.34 2.72 3.65 3.42
## PLEKHG6 0.25 0.61 0.70 0.55 0.12 1.30 0.78
## SS18L2 36.68 28.74 36.73 35.40 32.56 35.68 33.03
## MPND 11.63 11.20 8.81 11.02 9.13 9.58 9.81
## MGST1 731.07 671.51 762.55 744.37 791.08 800.54 685.55
## CRY1 8.84 11.82 11.31 8.89 10.74 9.78 10.91
## PGLYRP1 0.00 0.09 0.00 0.00 0.00 0.12 0.31
## NFIX 18.25 24.65 20.50 18.08 13.29 20.93 17.72
## ST3GAL1 139.42 187.85 119.39 119.00 124.45 143.11 127.15
## MMP25 0.97 1.51 0.69 1.12 2.27 1.83 1.58
## IL32 8.93 7.71 8.13 6.39 6.51 7.23 14.68
## PKD1 25.62 38.26 29.18 43.50 25.92 35.51 25.34
## MAPK8IP2 0.84 1.21 0.87 1.31 1.21 1.16 1.20
## MED24 56.43 64.63 60.93 58.80 48.57 51.60 42.84
## RHOBTB2 8.71 11.44 10.76 11.98 10.53 11.65 8.33
## HEATR5B 2.82 4.74 5.21 4.32 3.74 4.85 2.60
## SEC62 92.09 124.87 88.84 100.01 163.24 131.42 130.79
## RPS20 2991.89 2267.58 2453.02 2445.37 2572.92 2315.66 2831.33
## CSDE1 255.29 368.13 287.43 277.90 286.33 325.38 306.39
## UBE3C 47.16 69.20 61.89 60.89 56.47 72.53 49.80
## REV3L 5.49 8.40 7.83 6.66 7.79 8.39 6.51
## TENM1 0.01 0.02 0.02 0.00 0.00 0.01 0.00
## PAX7 0.02 0.00 0.00 0.00 0.01 0.00 0.00
## MASP2 0.56 1.24 1.16 1.55 1.10 1.69 1.01
## IYD 0.04 0.12 0.12 0.01 0.08 0.16 0.13
## FAM76A 4.10 6.41 4.44 5.50 5.35 5.52 6.53
## TRAF3IP3 1.74 2.85 1.82 1.84 2.47 2.20 2.12
## POMT2 8.33 11.25 11.60 13.64 13.76 10.66 10.78
## VTA1 18.36 19.48 22.98 19.92 24.63 24.78 21.10
## MLXIPL 0.94 2.68 1.32 1.09 1.59 1.13 3.20
## BAZ1B 23.41 37.67 31.21 33.61 30.54 40.05 28.44
## RANBP9 12.46 16.16 16.55 13.56 14.32 16.96 12.65
## ETV7 0.21 0.35 0.16 0.06 0.27 0.04 0.47
## SPRTN 7.07 8.68 7.85 9.64 9.96 11.54 7.08
## METTL13 18.55 21.49 21.65 20.59 24.09 21.16 20.17
## DYRK4 39.98 36.90 42.32 32.53 28.17 24.64 33.68
## ZNF207 134.49 145.30 177.34 149.18 154.26 171.77 147.52
## UQCRC1 224.19 191.68 203.70 215.08 182.72 188.19 188.32
## STARD3NL 49.43 53.01 60.89 53.05 49.13 56.20 46.30
## CD9 77.82 77.77 80.40 72.15 53.38 66.91 53.97
## HHATL 0.05 0.19 0.12 0.26 0.18 0.13 0.05
## NCAPD2 15.77 21.29 23.55 20.79 14.88 17.65 14.38
## IFFO1 17.48 22.64 20.99 18.61 13.95 12.92 11.80
## GIPR 1.14 3.17 2.04 1.95 1.60 1.53 1.74
## PHF7 7.96 11.50 6.40 6.18 6.36 7.95 11.65
## SEMA3G 0.10 0.25 0.09 0.16 0.15 0.12 0.22
## NISCH 20.77 29.05 23.75 24.70 25.43 24.57 26.92
## STAB1 0.96 0.67 0.53 0.57 0.52 0.71 0.73
## FUZ 13.70 11.12 12.19 9.03 9.52 7.59 12.07
## SLC6A13 0.64 1.03 0.65 1.22 0.70 1.29 0.92
## IDS 101.10 131.48 126.87 91.87 96.36 133.57 105.56
## PRSS3 12.73 10.24 21.29 17.53 13.63 13.55 7.92
## ZNF200 3.23 3.75 3.61 4.03 4.38 4.82 4.30
## CD4 0.87 0.85 0.53 0.40 0.35 0.47 0.43
## LRRC23 21.13 19.30 16.15 15.84 16.51 15.14 20.97
## BTK 0.20 0.11 0.10 0.17 0.37 0.18 0.65
## HFE 2.60 5.05 5.00 3.34 3.82 3.29 3.91
## SCMH1 11.89 13.14 12.24 11.36 8.91 10.99 10.84
## FYN 168.17 225.88 215.46 194.18 107.04 143.94 115.52
## HIVEP2 4.86 7.69 6.58 6.05 5.30 8.51 5.04
## FMO1 0.36 0.93 0.17 0.22 0.16 0.33 0.24
## TCEB3 27.15 33.80 29.72 33.71 40.21 43.00 35.50
## LYPLA2 54.07 51.79 64.35 59.77 50.16 50.65 40.15
## CLCN6 3.95 6.20 5.17 4.59 5.36 5.58 5.98
## MRC2 64.04 76.71 54.79 68.38 54.03 61.65 67.15
## NME2 489.61 256.03 584.06 410.98 414.68 428.39 408.69
## SLC6A7 0.89 1.42 0.50 0.28 0.48 0.28 2.59
## TSPAN9 16.74 21.61 13.98 13.73 9.00 14.02 12.39
## BTBD7 6.36 10.39 8.60 8.02 8.67 11.66 7.44
## APBA3 19.15 22.00 17.55 19.28 15.53 18.42 16.91
## MKS1 14.24 15.89 17.35 12.29 14.14 12.07 16.82
## ABHD5 21.03 18.06 27.86 30.10 29.57 31.40 23.76
## KAL1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## AKAP8L 54.09 61.66 46.87 57.62 63.28 61.50 57.24
## MBTD1 2.04 2.92 2.97 2.52 2.81 3.54 2.73
## UTP18 44.99 42.63 42.59 52.77 54.59 55.19 47.64
## RNF216 19.27 27.46 25.16 24.72 15.47 21.69 14.70
## TTC19 31.24 37.26 33.93 32.45 36.92 36.55 44.04
## PTBP1 112.02 113.10 115.17 155.51 125.74 148.23 95.96
## DPF1 9.24 11.58 15.39 19.14 12.23 11.07 8.84
## SYT7 0.95 1.30 1.34 1.06 0.61 0.75 0.70
## LARS2 10.52 14.17 14.96 13.44 12.04 13.12 10.33
## PIK3C2A 6.08 9.96 8.62 7.49 9.28 12.37 8.33
## PLAUR 239.93 242.57 293.17 253.33 209.57 233.19 168.85
## ANLN 10.30 14.76 28.03 21.00 14.65 13.59 9.68
## WIZ 15.74 20.37 19.22 19.95 19.28 20.78 16.46
## RABGAP1 8.91 13.68 11.02 11.64 9.88 12.32 10.02
## DCN 13.06 17.91 18.80 12.60 10.91 13.00 14.18
## QPCTL 34.99 34.33 21.53 25.19 25.17 28.51 39.99
## PPP5C 47.18 48.38 58.47 64.14 44.18 46.94 35.76
## CEP68 3.21 4.01 3.25 3.15 4.68 3.52 5.26
## MAP4K3 8.76 14.23 14.80 10.88 9.57 11.38 6.07
## ZBTB32 0.27 0.05 0.09 0.09 0.24 0.15 0.28
## TYROBP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMEM159 67.10 58.83 40.79 56.75 56.50 67.71 77.73
## GABRA3 1.29 1.68 2.05 1.86 1.03 1.31 1.19
## BRCA1 6.36 9.90 16.77 14.45 10.77 9.23 7.36
## ERCC1 114.80 105.13 111.65 116.00 116.26 104.18 112.64
## CD22 0.17 0.34 0.28 0.29 0.64 0.34 1.92
## MBTPS2 11.05 17.53 14.09 10.79 13.09 13.78 13.38
## PRICKLE3 12.43 13.73 8.58 11.29 11.52 15.24 13.06
## LTF 2.06 1.37 0.95 1.09 1.24 1.51 2.80
## EXTL3 13.52 19.32 14.05 16.65 15.51 19.76 14.94
## NR1H4 0.00 0.05 0.03 0.00 0.02 0.01 0.02
## ELOVL5 64.22 75.90 61.66 65.52 70.83 79.85 60.27
## ALOX5 0.00 0.00 0.00 0.00 0.00 0.29 0.00
## KDM5D 0.17 0.40 0.65 0.46 0.31 0.21 0.23
## CALCOCO1 32.00 44.83 33.85 24.93 21.20 28.25 31.57
## UBR7 20.25 23.10 33.51 29.73 23.28 23.38 14.72
## MAP4K5 10.23 14.37 15.89 15.03 15.98 18.23 11.47
## EHD3 6.54 9.09 7.60 6.59 5.60 7.59 6.36
## PSMC4 179.79 160.46 190.08 189.77 186.82 186.01 167.37
## MAN2B2 18.86 25.15 20.87 20.32 21.06 21.38 23.16
## SLC7A14 0.01 0.02 0.02 0.01 0.01 0.02 0.02
## CLDN11 0.37 0.60 0.30 0.63 0.21 0.49 0.22
## SLC25A39 133.45 117.49 134.99 140.29 149.44 125.56 139.38
## MVP 134.32 168.13 132.35 152.70 138.41 128.91 129.79
## NUB1 76.03 102.53 79.27 68.03 69.92 75.22 81.77
## PGM3 18.53 22.87 20.38 16.77 17.88 18.61 21.95
## RWDD2A 4.89 7.10 6.61 5.04 5.83 6.28 6.99
## CLK1 45.43 53.57 55.17 51.28 56.54 56.89 48.69
## POLR3B 1.56 2.32 2.28 2.09 2.28 2.31 1.86
## ANGEL1 6.68 8.09 6.04 6.00 6.86 7.04 7.81
## RNF14 33.50 37.87 38.33 33.49 49.82 43.94 53.05
## DNASE1L1 35.40 36.96 32.92 32.15 26.66 30.86 34.13
## DDX11 20.39 31.56 31.77 36.23 32.50 26.72 26.64
## HEBP1 64.94 58.76 52.98 56.82 66.01 62.12 64.34
## GPRC5A 22.27 21.25 28.73 32.78 24.28 43.95 20.84
## MAMLD1 12.24 19.45 15.90 15.96 10.09 13.56 11.55
## CD6 6.74 6.43 7.97 7.97 3.84 4.61 3.04
## TACC3 22.32 25.97 37.74 39.15 25.04 20.83 19.48
## UFL1 13.57 22.46 19.49 11.93 19.76 15.71 18.99
## POLA2 26.10 24.64 48.81 48.02 30.99 27.45 16.46
## ZC3H3 9.68 11.72 10.17 11.76 11.64 12.35 11.22
## CAPN1 48.38 53.40 58.86 64.59 42.86 54.99 34.65
## ACPP 4.14 6.88 17.80 7.42 3.18 4.11 1.62
## MDH1 237.52 215.07 249.85 219.37 210.62 208.74 212.37
## SLC30A9 40.47 57.43 54.54 45.94 51.86 50.80 47.04
## MTMR11 9.11 14.64 13.62 10.99 11.09 10.47 10.38
## COX15 17.12 22.38 19.35 19.95 20.10 24.46 20.46
## CCDC88C 0.57 0.83 0.47 0.34 0.32 0.32 0.26
## YAF2 14.93 16.74 14.85 16.28 16.30 14.83 14.02
## ZMYND11 21.52 28.51 28.69 24.64 27.75 29.00 22.31
## WAS 0.59 0.51 0.46 0.55 0.95 0.76 0.39
## DPEP1 0.17 0.32 0.05 0.21 0.29 0.23 0.44
## BID 106.58 82.60 94.06 88.82 58.62 72.43 62.06
## MATR3 153.19 201.91 202.48 177.92 205.13 199.06 176.55
## NPC1L1 0.19 0.15 0.22 0.31 0.14 0.38 0.07
## XYLT2 25.97 34.34 26.70 34.05 23.99 25.50 21.05
## RGPD5 2.85 6.03 5.75 3.84 4.56 4.68 5.71
## STMN4 0.36 0.40 0.48 0.33 0.40 0.31 0.39
## NUDCD3 27.64 31.74 27.05 32.24 34.18 30.47 32.66
## ISL1 0.08 0.20 0.34 0.15 0.22 0.23 0.18
## CHDH 0.05 0.14 0.05 0.03 0.04 0.06 0.05
## IL20RA 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## CLCA1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CLCA4 0.00 0.00 0.01 0.00 0.01 0.00 0.01
## GLT8D1 79.98 102.74 92.20 77.33 72.51 69.85 84.14
## ATP2C1 69.74 90.46 72.80 87.16 59.99 80.65 58.33
## SRCIN1 0.11 0.17 0.14 0.11 0.02 0.10 0.15
## IGF1 0.23 0.33 0.53 0.88 0.31 0.12 0.46
## SLC38A5 3.24 2.42 2.75 3.25 2.30 2.81 1.91
## MAGIX 2.14 1.83 1.50 1.99 1.22 1.93 1.54
## RALBP1 24.51 34.77 25.48 29.07 24.44 35.12 24.51
## RUFY3 24.58 40.10 26.50 27.67 28.90 33.59 32.96
## CNTN1 0.00 0.02 0.01 0.08 0.01 0.01 0.01
## SLC11A1 0.72 1.06 1.27 0.73 1.01 0.81 1.10
## WWTR1 28.62 44.39 37.60 31.03 25.79 39.51 25.28
## AGPS 8.01 11.30 11.98 11.09 11.06 13.05 8.37
## CXorf56 16.67 21.41 17.62 18.44 23.86 20.72 22.44
## ATP1A2 2.39 4.11 2.86 2.91 2.28 2.45 2.91
## TTC27 19.51 19.72 13.94 16.25 19.69 16.81 18.47
## ZNF582 0.31 0.22 0.03 0.02 0.19 0.08 0.12
## VSIG2 0.79 0.58 0.68 0.87 0.66 0.44 0.69
## PHLDB1 11.51 15.26 14.61 14.20 9.29 10.32 11.22
## MARCO 0.21 0.12 0.13 0.00 0.12 0.07 0.12
## CYP24A1 0.04 0.34 0.14 0.03 0.03 0.26 0.05
## PRDM11 0.35 0.41 0.14 0.37 0.32 0.14 0.36
## SYT13 0.02 0.02 0.00 0.00 0.00 0.01 0.01
## SNAI2 49.90 54.52 55.99 56.72 67.05 57.88 61.08
## CD74 3744.78 3542.72 3027.80 2852.34 3046.73 3151.52 3918.17
## HGF 5.99 9.59 10.94 5.86 4.50 4.78 5.65
## ZRANB1 10.67 15.13 12.29 14.13 12.00 16.44 10.13
## NCDN 32.70 35.66 34.12 37.52 44.47 46.91 43.81
## GPR124 0.39 0.36 0.30 0.15 0.15 0.18 0.30
## ZFP64 12.20 16.69 13.18 12.19 15.13 16.40 15.91
## MNAT1 52.17 53.77 52.95 53.42 46.32 46.35 45.70
## SAMD4A 10.32 12.65 9.80 13.48 9.77 14.76 9.19
## RUNX3 0.01 0.03 0.03 0.00 0.01 0.00 0.05
## MRE11A 2.90 4.93 4.67 4.31 4.02 3.82 2.77
## PLEKHB1 1.44 1.52 1.44 1.19 2.47 1.28 2.07
## SERPINB1 22.67 26.96 21.80 19.33 25.36 21.68 28.93
## CYP3A43 0.00 0.04 0.11 0.05 0.04 0.13 0.11
## SLC7A9 0.23 0.07 0.16 0.25 0.18 0.29 0.10
## SPAST 5.08 8.42 6.30 6.13 7.74 7.77 5.81
## NRXN3 0.13 0.17 0.15 0.34 0.15 0.11 0.08
## OSBPL5 10.71 10.71 10.36 11.07 8.13 8.45 7.78
## AQR 11.66 15.91 16.30 13.86 17.09 14.17 17.15
## CPS1 5.02 7.81 6.13 5.47 2.94 4.86 3.73
## C8B 0.03 0.13 0.10 0.01 0.12 0.10 0.19
## FHL1 7.15 8.41 9.32 7.70 5.21 6.62 6.05
## RTFDC1 160.92 155.39 156.05 145.58 146.20 142.75 156.93
## GABRA1 0.00 0.02 0.00 0.07 0.02 0.04 0.04
## NLRP2 0.08 0.42 0.12 0.10 0.18 0.42 0.19
## SLC45A4 2.22 2.51 1.83 1.73 1.68 2.18 2.05
## RNF10 136.10 113.05 88.65 124.00 135.39 136.33 120.04
## ZNF839 9.00 12.34 9.21 11.04 9.31 8.81 11.09
## ZDHHC6 27.85 30.78 32.31 32.24 32.53 31.91 32.37
## GRAMD1B 2.11 2.96 2.51 2.71 1.36 2.54 1.12
## RNH1 165.10 147.50 149.66 154.16 151.08 143.67 164.88
## NDUFS1 23.24 34.90 30.38 25.92 26.02 27.28 32.87
## RB1CC1 15.19 25.16 13.47 14.26 14.07 22.27 17.74
## ERP44 22.82 25.13 20.30 20.90 22.55 24.68 20.78
## ALAS1 65.44 69.72 68.80 78.76 79.25 95.99 72.31
## BIRC3 19.61 27.99 15.13 11.94 8.57 11.32 10.75
## AKAP11 5.82 12.96 11.53 8.24 9.89 12.49 9.23
## GLRX2 41.15 33.10 43.58 42.81 53.66 44.37 46.60
## SNAPC1 29.78 27.31 27.55 41.18 71.53 49.29 63.60
## DERA 44.85 43.82 50.48 39.33 37.14 36.99 42.89
## STRAP 149.77 152.45 168.13 151.48 185.80 179.06 160.88
## ABCC2 2.86 5.05 3.35 4.15 3.99 5.91 4.28
## DEF6 0.18 0.17 0.10 0.38 0.64 0.26 0.24
## PLEKHO1 111.06 93.78 107.38 128.19 80.05 92.89 60.61
## GCLM 60.46 73.46 58.59 59.68 64.29 83.65 69.15
## UBR2 2.31 3.45 2.40 2.50 2.41 3.12 2.86
## EHD2 49.31 64.09 52.40 54.83 35.30 47.70 35.35
## DEPDC1 6.97 9.64 12.50 8.35 8.71 8.54 6.11
## CCDC28A 7.35 8.99 6.10 4.75 5.48 5.47 5.96
## RRAGD 5.46 6.25 6.72 6.77 11.93 10.14 9.90
## HSF2 9.22 11.83 10.74 10.63 12.60 12.33 10.89
## PHF20 14.69 23.37 17.92 16.37 15.38 20.46 16.94
## HSD17B6 1.97 2.55 2.80 1.46 2.03 2.56 2.92
## NR1H3 20.94 19.38 18.69 17.06 18.15 12.50 21.07
## TYMP 4.16 4.49 3.76 2.56 2.88 1.98 3.98
## NCAPH2 42.90 36.37 50.05 52.67 36.41 38.08 34.24
## TOMM34 91.88 92.29 110.54 102.29 107.45 100.67 101.62
## SEC63 36.50 55.12 44.33 54.37 52.08 49.50 40.48
## KPNA6 18.58 28.64 17.06 20.75 21.32 26.35 25.19
## VIM 3515.28 3490.65 3959.34 4423.10 3246.52 3309.37 3052.78
## RTEL1-TNFRSF6B 1.04 1.94 2.19 2.51 1.74 1.44 2.02
## FAS 19.78 22.95 24.82 21.84 33.43 27.52 31.09
## RNASET2 25.74 27.06 25.06 25.93 23.82 23.22 26.39
## CD44 823.10 1024.29 943.01 828.47 793.36 874.86 709.01
## KCNG1 27.08 23.90 19.41 20.39 22.44 21.14 28.11
## AGPAT4 22.53 29.49 20.78 21.56 12.24 18.45 13.96
## SLAMF7 7.22 6.60 7.70 7.57 8.40 7.21 9.16
## BTN3A1 7.03 12.70 7.34 4.17 4.39 4.67 8.44
## MIPEP 7.44 10.25 9.69 9.66 8.43 8.73 8.79
## PRKCH 6.30 6.51 6.18 6.46 6.69 6.34 6.85
## INSRR 0.01 0.01 0.01 0.01 0.00 0.00 0.01
## IFNGR1 21.85 28.22 24.76 22.16 24.44 26.97 23.49
## B4GALT7 37.60 38.18 45.39 37.13 36.02 31.08 36.67
## SH2D2A 2.44 2.48 2.47 1.54 1.08 0.90 1.00
## VRK2 10.72 13.55 15.30 12.16 12.37 12.26 12.75
## TNFRSF1B 33.70 36.29 35.63 47.47 40.02 49.55 36.02
## VEZT 9.43 12.78 15.19 11.50 13.75 14.16 12.69
## POU2F2 40.83 69.10 36.32 37.17 17.35 30.87 25.38
## BRD9 29.01 37.03 31.04 39.69 41.14 37.47 41.30
## SNX1 37.98 49.55 52.32 45.97 35.51 46.51 37.29
## TBPL1 31.80 27.83 31.63 33.38 38.85 36.79 33.92
## ARNTL2 12.33 17.67 18.48 16.05 13.76 17.30 12.08
## BCLAF1 20.86 37.62 27.36 32.05 32.53 33.61 29.43
## SLC39A9 37.03 45.79 35.48 41.04 40.28 51.42 39.14
## ANK1 12.54 19.04 7.32 7.38 5.35 6.88 12.18
## IBSP 0.06 0.14 0.00 0.03 0.04 0.16 0.07
## TFB1M 21.45 19.76 23.16 23.07 16.46 17.71 15.77
## RABEP1 25.93 25.24 26.45 27.61 25.99 30.35 26.72
## HMGB3 22.84 31.36 26.96 26.47 29.21 25.17 27.92
## NUP160 11.54 16.18 15.85 15.19 14.36 16.94 12.46
## BAK1 13.09 11.75 11.52 14.45 16.18 17.64 14.62
## MUSK 0.03 0.02 0.03 0.03 0.05 0.00 0.06
## IKZF2 1.43 2.22 1.43 0.78 0.77 0.44 0.77
## GRN 162.06 185.74 153.68 181.93 204.71 209.29 183.62
## FAM13B 5.49 7.07 9.29 7.41 8.27 9.18 6.77
## ARHGAP31 8.61 11.66 10.23 9.12 6.74 9.52 6.02
## CENPQ 9.35 9.72 19.76 14.12 14.18 10.06 8.59
## SARS 211.50 214.68 179.73 167.64 202.50 185.32 271.51
## RANBP3 39.04 46.13 40.24 42.13 42.15 49.96 36.02
## ARID4A 2.32 4.68 2.80 2.77 2.68 3.81 2.95
## TSSC1 18.59 15.45 22.89 20.09 18.01 17.72 16.79
## PNPLA6 70.26 81.24 57.05 87.16 73.20 77.18 66.40
## IFT88 2.95 4.54 4.53 3.49 3.37 2.81 3.00
## ALG1 11.25 9.68 11.34 12.87 13.51 12.08 11.09
## ZCCHC8 15.29 19.44 20.54 20.32 21.02 21.31 17.91
## ABCF2 91.47 102.61 108.03 114.81 132.31 126.75 116.01
## CHPF2 70.62 89.12 72.51 93.01 67.95 89.70 59.78
## LRRC7 0.34 0.45 0.35 0.46 0.47 0.21 0.17
## FUT8 23.14 29.85 26.35 25.31 13.83 19.83 13.34
## UBA6 17.32 24.54 29.40 25.28 20.53 26.02 18.00
## GAB2 1.33 2.38 1.22 1.36 1.16 2.00 2.10
## ATP6V0A1 22.96 28.70 24.27 32.81 28.95 32.94 29.89
## PIAS1 8.16 12.76 11.65 8.75 9.18 11.49 9.78
## SLC4A7 12.25 22.19 19.34 18.87 17.23 26.06 15.72
## APBA2 0.09 0.04 0.09 0.02 0.08 0.07 0.07
## MAP2K3 116.89 120.95 82.51 123.33 99.83 119.31 107.47
## EFCAB1 3.10 3.16 2.22 2.63 2.10 2.29 3.30
## TMSB10 6791.14 4845.94 6936.12 6062.47 5563.06 5085.65 5629.15
## ASTE1 3.66 4.25 4.60 3.90 4.83 3.64 4.81
## RNF19A 12.49 20.06 14.45 13.06 12.37 15.95 13.42
## PEX3 25.48 29.08 45.72 35.39 35.65 33.41 23.17
## GABARAPL2 169.09 148.25 146.35 144.05 138.49 153.99 135.19
## MYOC 0.01 0.00 0.00 0.01 0.02 0.04 0.03
## SH3YL1 22.37 27.01 20.18 21.84 28.28 23.56 31.89
## FAM136A 66.78 65.85 70.55 81.43 82.55 75.44 62.46
## VCL 53.60 76.70 75.36 62.76 51.95 63.74 49.04
## DEPDC1B 5.09 6.38 7.70 6.02 5.43 5.59 4.28
## DAPK2 0.20 0.24 0.16 0.34 0.18 0.13 0.44
## NSMAF 39.06 47.68 41.83 39.33 44.60 50.71 52.55
## ADSS 18.21 23.84 20.60 20.76 24.86 21.81 25.60
## STAP1 0.00 0.13 0.00 0.10 0.15 0.05 0.06
## TIMP2 35.16 47.64 37.96 39.29 34.21 41.85 37.66
## RFC1 18.08 28.04 23.29 27.19 26.57 25.16 23.62
## TBC1D23 17.26 23.17 22.15 18.26 20.32 20.43 17.41
## CUL3 64.84 67.41 63.94 69.21 78.76 80.80 62.77
## MYOM2 3.47 2.52 2.86 3.66 3.80 3.65 6.47
## OTC 0.13 0.00 0.00 0.00 0.13 0.15 0.04
## CYP46A1 0.57 0.75 0.61 0.46 0.48 0.33 0.64
## ZZZ3 17.81 24.48 20.99 20.79 25.82 29.32 24.84
## SLC18A1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## USP2 0.14 0.35 0.08 0.08 0.14 0.06 0.18
## CASR 0.01 0.00 0.01 0.00 0.00 0.00 0.00
## TUBG2 23.12 26.49 25.32 25.13 20.45 20.84 18.95
## RPL26L1 157.18 118.80 139.04 140.75 146.48 126.73 140.40
## FLT4 0.10 0.01 0.01 0.01 0.01 0.01 0.01
## NSUN2 36.14 46.83 51.88 56.61 60.72 56.06 48.98
## FBXO42 12.99 16.69 14.95 17.33 12.02 15.99 12.07
## MFAP3 15.23 19.93 17.22 14.75 17.77 22.49 17.39
## MRI1 11.23 14.71 18.77 15.08 9.03 12.44 7.79
## METTL1 37.03 26.60 36.88 33.65 40.98 28.06 43.64
## HOXC8 2.92 3.87 2.27 2.72 3.22 2.88 2.57
## AGA 9.19 11.61 12.76 7.88 11.18 11.96 8.87
## PI4K2B 12.44 18.89 19.32 14.19 16.55 15.10 15.44
## BOD1L1 9.44 15.00 14.65 14.54 12.49 13.17 13.28
## MAT2B 30.23 35.81 33.29 28.27 31.75 32.36 33.61
## TLL1 0.02 0.00 0.02 0.07 0.00 0.00 0.02
## EDC4 36.76 44.07 43.83 47.66 44.39 44.24 39.18
## TRIO 71.81 132.98 134.80 111.15 54.23 84.35 56.49
## VCAN 19.81 36.11 29.58 24.36 18.01 22.38 25.88
## CLEC16A 9.70 13.49 10.05 12.38 8.56 10.75 8.11
## MSR1 0.20 0.04 0.04 0.15 0.03 0.30 0.07
## CDH1 0.25 0.46 0.18 0.40 0.46 0.39 0.29
## SKIV2L2 26.74 44.25 29.86 33.85 31.17 33.24 30.99
## DNAH5 0.90 1.46 1.27 0.76 0.95 0.62 0.76
## ZFYVE16 6.87 14.64 9.78 11.95 10.32 10.17 12.28
## FAM65A 31.57 39.21 28.87 38.38 33.12 39.96 40.80
## C6 0.00 0.00 0.00 0.00 0.07 0.00 0.01
## RAI14 83.57 108.13 110.39 116.37 97.50 127.49 86.65
## SOX30 0.35 0.43 0.24 0.20 0.36 0.37 0.27
## PNKP 25.78 26.67 32.04 30.32 25.78 24.74 25.47
## BEST2 0.25 0.23 0.26 0.11 0.35 0.50 0.24
## PHLPP2 4.48 7.16 5.41 6.31 6.72 9.17 6.16
## SPDL1 17.43 24.46 33.74 31.22 25.49 21.97 19.55
## STAU2 12.31 17.19 18.76 11.05 9.26 13.20 11.47
## PQLC2 30.00 27.14 28.59 38.96 38.01 39.64 32.65
## CTNS 10.00 10.50 12.94 12.55 16.02 17.51 14.32
## RTN4R 0.21 0.35 0.28 0.18 0.32 0.33 0.31
## PHF23 46.50 44.67 51.14 55.48 54.02 50.53 45.65
## CDH10 0.03 0.08 0.04 0.02 0.05 0.08 0.03
## INPP4A 5.22 8.90 7.72 6.38 5.04 8.47 5.33
## RAB27B 31.79 62.23 52.28 30.45 33.28 37.38 33.64
## PSMA4 207.37 198.44 228.45 222.02 191.34 193.88 186.52
## MYO16 0.42 0.70 0.80 0.53 0.73 0.65 1.03
## LSG1 24.11 29.09 25.84 30.03 36.96 33.20 37.73
## PARP3 28.85 32.82 32.04 25.87 24.68 21.25 29.79
## TNC 548.47 639.00 660.33 647.98 403.67 460.52 558.47
## THAP3 26.01 20.06 21.04 20.40 21.26 20.79 22.39
## FAM65C 25.06 39.27 36.37 27.95 10.44 17.18 13.02
## TDP1 19.55 24.01 23.94 23.84 19.23 21.86 15.35
## AIFM2 17.41 19.32 15.59 19.60 25.50 24.28 28.22
## C2orf83 0.03 0.04 0.00 0.00 0.04 0.02 0.02
## SPATA7 5.48 7.57 5.97 4.38 4.17 5.42 5.22
## MED17 13.63 16.75 13.89 16.22 19.58 19.53 17.62
## RETSAT 29.69 34.52 30.99 30.54 35.10 33.81 40.29
## CAPG 253.81 194.44 221.24 212.23 207.16 193.34 221.21
## AP2S1 327.86 248.10 303.88 301.05 274.55 273.04 245.79
## USH2A 0.01 0.02 0.01 0.12 0.01 0.01 0.05
## ZPBP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TG 2.12 3.57 3.68 3.90 3.22 3.25 3.42
## ADAM28 1.28 1.90 1.83 0.94 0.68 1.22 1.14
## BARX2 0.00 0.01 0.00 0.00 0.00 0.00 0.02
## DCUN1D1 13.98 17.89 14.65 12.84 17.69 23.92 17.50
## JADE2 13.86 21.26 13.70 11.58 11.49 13.62 16.29
## ZIC2 5.70 6.05 6.13 6.95 9.99 7.26 7.68
## LCP2 0.26 0.19 0.16 0.14 0.14 0.07 0.49
## TRIT1 33.69 32.21 30.20 32.33 30.74 31.88 32.76
## ADRB1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GUCA2B 0.00 0.11 0.00 0.00 0.07 0.00 0.00
## CUL7 6.71 8.82 6.92 7.46 6.42 6.91 7.04
## CTNNA1 125.03 177.03 159.31 151.30 131.35 150.12 136.64
## PHKA2 7.32 11.61 8.01 8.51 7.59 8.74 7.30
## CNTLN 2.17 3.40 3.23 2.18 2.17 2.50 2.01
## EPHA3 0.49 0.91 1.87 0.82 0.29 0.54 0.11
## HSPA5 222.30 278.68 227.95 241.02 243.92 244.76 347.36
## DSG2 6.15 9.33 8.97 6.41 6.77 8.42 6.82
## GEMIN8 12.85 11.98 11.89 11.52 13.19 11.35 15.58
## OFD1 20.55 26.42 16.98 20.09 19.65 20.21 18.08
## GPM6B 0.34 0.49 0.41 0.38 0.34 0.50 0.41
## MAGEC2 1.99 2.11 2.41 2.04 2.45 2.09 2.33
## PREX2 0.00 0.00 0.01 0.00 0.01 0.00 0.00
## WDR37 14.64 20.13 15.24 16.23 18.88 21.79 17.03
## YTHDC2 4.60 8.56 6.14 4.81 6.04 6.12 6.01
## CTPS2 2.94 5.42 3.45 3.30 2.58 3.27 2.73
## ATP6V1H 39.49 45.02 42.09 44.78 56.38 52.13 58.40
## POLR2B 40.58 57.78 49.38 56.77 52.83 60.74 45.62
## FAM214A 6.63 10.99 9.26 8.97 6.86 11.37 6.59
## ARAP2 0.84 0.50 0.70 0.45 0.89 0.92 0.74
## TPR 14.57 20.85 22.28 19.53 18.04 17.12 15.74
## CP 1.04 0.65 0.30 0.67 0.94 1.17 0.82
## KIAA0556 13.79 19.46 16.64 13.85 8.90 12.55 10.32
## DTNBP1 5.79 5.12 4.59 5.72 5.92 6.11 4.54
## XK 0.25 0.52 0.41 0.30 0.48 0.43 0.32
## ANO2 0.25 0.33 0.20 0.07 0.04 0.04 0.32
## C12orf4 9.51 12.69 14.98 10.83 14.15 11.30 13.00
## SCML1 11.72 14.71 16.66 17.19 23.10 22.46 16.27
## WWC3 8.32 11.99 8.30 8.64 9.27 9.53 12.58
## ARHGAP6 0.30 0.28 0.11 0.20 0.08 0.08 0.11
## FAM184B 0.74 1.58 0.93 1.28 1.26 1.25 1.47
## MAP4 106.30 164.94 118.92 130.90 100.21 134.42 119.11
## GOPC 11.29 16.43 14.79 13.47 14.20 14.96 13.76
## ROS1 0.22 0.21 0.37 0.18 0.07 0.29 0.15
## USP28 1.87 1.78 1.88 1.39 1.86 2.08 1.84
## HDAC9 4.20 4.87 4.91 3.35 7.52 6.63 5.55
## TSPAN17 41.40 42.61 41.24 46.41 46.62 48.35 38.81
## NOP16 73.17 48.52 55.47 73.86 88.12 77.54 79.27
## CC2D2A 9.97 12.94 13.29 14.42 11.33 10.97 16.00
## RRM2B 32.99 53.00 33.77 25.94 31.11 38.71 42.56
## ZNF800 14.32 19.60 14.69 15.23 21.26 24.60 21.28
## TNFRSF17 0.08 0.12 0.18 0.14 0.18 0.08 0.11
## SNX29 8.12 10.55 7.14 7.88 4.78 8.05 6.40
## LMO3 0.54 0.52 0.29 0.84 0.20 0.56 0.24
## MRPS10 28.38 29.23 29.76 26.48 34.12 28.85 31.91
## GUCA1A 0.00 0.02 0.00 0.02 0.00 0.00 0.00
## RSF1 3.57 5.22 5.83 4.66 4.83 4.95 3.95
## VPS13D 8.40 14.31 9.77 10.29 8.43 10.69 8.35
## CELF2 0.01 0.05 0.04 0.05 0.03 0.05 0.08
## FAM120A 51.50 72.84 60.68 62.46 68.30 72.64 54.28
## R3HDM1 13.76 17.57 18.64 15.90 14.70 20.70 14.34
## COL9A2 1.36 1.88 1.36 1.43 1.62 1.11 2.53
## KITLG 3.70 5.17 4.51 4.85 7.81 8.46 7.06
## ERCC8 13.00 13.52 13.97 12.60 12.79 15.13 16.19
## ADAMTS6 5.58 6.22 7.08 6.31 4.41 6.37 6.92
## H6PD 13.31 23.85 13.05 13.66 12.03 14.39 18.09
## VAMP3 101.89 115.09 110.66 104.11 131.63 123.51 120.29
## PER3 4.35 6.15 5.55 4.15 4.47 5.27 5.70
## UTS2 0.22 0.28 0.06 0.05 0.24 0.00 0.12
## TNFRSF9 2.69 3.79 3.33 2.40 2.11 2.65 4.80
## EPN3 0.18 0.02 0.05 0.00 0.00 0.10 0.12
## LTBP1 82.68 111.65 81.25 78.10 38.06 64.80 47.63
## RCN1 436.58 505.04 420.38 437.97 525.34 474.12 483.06
## ELN 0.19 0.38 0.44 0.40 0.18 0.13 0.51
## RFC2 28.64 26.50 51.77 46.82 34.30 28.37 26.76
## ARID1B 6.08 10.02 7.53 6.59 5.02 8.21 6.12
## CLPTM1L 85.47 95.57 75.31 106.41 112.18 107.42 84.71
## NEDD4L 33.83 46.94 40.71 41.36 27.86 44.99 27.91
## FOXP3 0.06 0.07 0.20 0.07 0.10 0.08 0.27
## PPP1R3F 3.59 4.29 2.23 3.40 2.96 2.82 3.19
## HEXB 187.96 210.52 213.07 218.73 235.57 225.34 199.56
## PTCD2 6.99 8.56 8.55 7.12 9.46 9.37 12.46
## KIAA2022 0.00 0.00 0.00 0.00 0.01 0.00 0.00
## JKAMP 71.76 78.82 83.56 83.51 85.62 86.99 77.65
## DKK3 26.99 31.53 23.33 22.41 19.89 24.20 25.28
## ARHGEF5 2.91 4.22 2.18 2.89 3.25 3.51 3.58
## NFE2L3 0.38 1.27 1.16 1.31 1.13 1.02 0.84
## MCUR1 20.41 18.12 18.85 18.32 22.27 20.85 21.70
## LIMA1 63.92 60.96 61.47 70.28 67.38 75.07 59.78
## LETMD1 51.88 58.63 48.58 51.23 45.49 46.83 63.50
## SLC4A8 2.81 3.68 3.35 2.58 3.55 2.44 3.62
## LAMC3 0.01 0.01 0.01 0.00 0.05 0.01 0.01
## PTGER3 0.39 0.48 0.58 0.43 0.57 0.54 0.43
## TNIP3 25.75 34.19 21.35 17.68 25.00 34.84 31.34
## MAPK9 19.10 24.79 26.21 24.14 22.38 23.62 19.85
## COL23A1 0.22 0.10 0.10 0.02 0.05 0.08 0.19
## BCAR1 40.02 47.98 39.48 54.31 49.90 49.78 41.36
## FAM160A2 20.29 27.21 21.20 24.86 27.48 22.93 26.88
## HERPUD1 71.65 71.60 62.12 66.01 59.17 71.80 73.65
## HOMER3 180.67 147.21 172.36 192.62 175.08 166.51 151.39
## RAD51 11.55 11.14 24.10 22.12 16.12 12.37 8.13
## POLQ 0.66 1.18 2.31 2.54 1.17 1.33 1.13
## PIK3CB 9.19 15.15 11.65 10.08 9.37 12.17 8.80
## CYBA 233.60 158.98 199.96 186.79 180.03 165.60 196.42
## THOC3 19.83 25.63 23.00 29.36 21.76 20.63 18.58
## HEBP2 52.34 45.78 39.82 42.18 38.48 38.20 43.20
## MPHOSPH9 8.54 13.17 10.12 10.70 10.92 9.72 11.48
## PLEKHA5 5.33 7.20 4.95 4.92 6.03 5.59 5.45
## PRSS8 0.07 0.06 0.04 0.08 0.28 0.09 0.07
## SIKE1 91.79 79.86 71.22 64.64 71.02 67.61 92.90
## RRP12 43.98 43.93 30.68 44.83 62.52 45.57 64.87
## FNIP2 4.44 8.47 7.90 6.91 9.96 12.46 7.45
## MSMO1 25.01 25.95 24.80 22.67 29.59 31.34 30.93
## TTC17 29.81 41.86 32.76 35.50 36.24 43.42 31.50
## ALX4 0.01 0.02 0.01 0.00 0.01 0.01 0.01
## FSTL4 0.18 0.18 0.32 0.17 0.30 0.33 0.26
## FOXN3 3.82 6.68 4.86 3.46 2.66 4.11 2.31
## METTL24 0.00 0.00 0.00 0.00 0.00 0.00 0.03
## AKR7A2 56.99 51.47 54.08 47.54 42.03 41.80 47.86
## MRTO4 68.53 57.87 64.77 70.71 90.92 73.02 90.63
## NNAT 0.59 1.61 1.01 1.11 0.77 0.88 1.43
## USE1 42.17 30.01 33.44 35.34 38.29 34.68 48.31
## MCF2L2 1.72 1.46 1.13 1.02 0.94 1.15 1.41
## NRIP2 0.52 0.99 0.61 0.40 0.51 0.44 1.16
## LAMA3 2.95 4.07 3.35 3.23 2.47 2.53 3.39
## AP5M1 18.93 21.61 20.44 17.10 20.70 26.02 21.21
## ANAPC4 10.69 14.06 15.16 14.43 13.74 13.40 12.75
## KCNQ1 0.34 0.16 0.08 0.03 0.07 0.08 0.11
## TRAPPC3 131.37 129.75 119.64 145.03 154.22 154.40 140.32
## THRAP3 25.24 39.68 31.78 38.89 34.95 41.68 33.83
## PHPT1 179.71 151.35 203.74 161.99 134.86 118.68 157.95
## ENTPD2 0.11 0.07 0.10 0.08 0.04 0.05 0.13
## LY75 0.01 0.01 0.00 0.00 0.00 0.03 0.00
## ARID4B 6.22 12.05 9.41 7.83 6.24 11.01 6.70
## OPN3 5.45 5.09 4.10 6.46 4.31 7.07 4.04
## SDCCAG8 18.63 25.79 17.60 22.23 17.02 17.98 13.24
## PTPRN 199.73 230.45 200.10 198.53 196.82 181.77 209.91
## HHAT 0.99 1.82 0.88 0.90 0.75 0.80 1.02
## KIF1B 9.48 18.61 14.98 13.49 16.14 20.57 13.85
## FOXC1 3.70 4.13 2.93 3.10 5.07 3.38 5.04
## TBC1D22A 17.46 19.34 19.63 19.03 12.57 13.92 12.82
## SYNE2 1.50 2.15 2.60 1.87 1.12 1.81 1.92
## PLEKHH1 1.78 4.53 2.66 3.12 2.00 2.15 1.71
## ATP9A 6.00 11.00 6.21 4.63 4.84 5.95 6.29
## SPO11 0.00 0.02 0.00 0.00 0.00 0.05 0.00
## CBLN4 0.01 0.00 0.00 0.02 0.00 0.00 0.00
## CHRDL2 0.02 0.17 0.00 0.06 0.12 0.00 0.00
## FAM168A 6.97 10.79 9.23 8.09 4.86 8.60 5.23
## RELT 17.90 18.68 18.49 18.66 16.66 19.89 14.01
## GALC 1.36 2.11 1.83 1.36 1.58 1.61 1.45
## NOP58 93.98 95.86 84.92 104.49 130.34 104.65 129.55
## SZRD1 97.11 105.93 111.27 100.17 97.78 111.32 94.05
## KCNH2 0.27 0.29 0.24 0.15 0.12 0.15 0.12
## CUL1 56.46 73.38 67.20 66.94 63.13 74.08 60.22
## FAM114A2 21.04 27.59 24.01 19.88 28.20 24.21 28.85
## CYFIP2 9.26 11.79 8.90 9.07 7.44 7.48 8.28
## TAB2 39.01 52.46 48.26 41.64 35.87 52.15 31.61
## GINM1 42.22 47.52 46.80 44.11 48.65 47.20 48.92
## EIF2AK2 7.36 12.58 10.23 9.75 9.47 12.57 8.83
## USP36 30.67 35.38 28.75 36.74 63.48 50.45 67.96
## KMT2C 6.56 11.41 9.94 9.94 7.26 10.28 6.90
## MCOLN3 0.01 0.01 0.02 0.00 0.04 0.01 0.02
## CCDC85A 0.01 0.02 0.01 0.01 0.02 0.01 0.02
## PUM2 13.67 21.58 17.82 16.33 16.46 20.53 15.70
## MRPL43 79.26 63.91 79.98 73.62 69.94 66.66 71.82
## ITIH4 2.09 1.39 0.98 0.97 1.24 0.85 1.80
## ITIH1 0.70 0.78 0.70 0.62 0.58 0.56 1.84
## C4orf27 36.84 40.21 43.78 39.44 38.57 36.78 37.12
## ZFR 34.97 49.67 38.33 42.35 48.49 51.86 46.85
## ZNF280C 1.45 2.15 1.50 1.46 2.43 3.01 3.02
## NPFFR2 0.15 0.02 0.00 0.05 0.03 0.07 0.06
## PHF21B 0.02 0.04 0.00 0.03 0.02 0.06 0.16
## TRAF1 11.86 14.58 8.34 7.31 11.22 10.19 14.41
## RC3H2 11.95 21.12 34.03 16.33 30.51 25.88 18.06
## PCGF2 25.66 32.08 26.39 35.06 25.23 28.08 22.27
## IL17RB 0.85 1.71 1.22 1.37 1.21 1.66 1.26
## TRAF3IP2 75.01 81.27 74.98 57.70 67.58 62.75 67.09
## GYG2 0.00 0.03 0.01 0.00 0.00 0.00 0.01
## DCBLD2 76.08 101.53 121.73 120.03 120.36 132.74 88.66
## SERPINB3 0.49 0.88 0.99 0.41 0.47 0.49 0.55
## SOAT1 12.47 17.24 15.11 15.60 19.94 24.53 18.40
## PKP2 0.00 0.07 0.00 0.00 0.02 0.00 0.01
## MSH4 0.09 0.20 0.13 0.09 0.19 0.22 0.14
## F7 0.10 0.06 0.12 0.12 0.07 0.05 0.18
## GDI2 150.61 158.37 159.36 174.47 187.95 204.24 156.33
## PRDM1 13.59 25.55 16.68 12.89 17.25 18.61 18.36
## ATG5 27.40 28.12 34.25 28.47 30.28 33.00 25.37
## TMCC3 4.06 5.55 4.89 4.30 6.34 7.10 5.02
## PITHD1 91.36 85.36 80.03 95.72 112.28 106.98 94.77
## MTA3 17.69 21.02 20.81 18.59 17.78 16.89 14.29
## USP13 5.59 9.06 6.72 5.58 5.33 5.71 6.08
## ATP11B 7.81 13.80 11.71 10.05 8.13 12.20 8.70
## LAMC2 6.64 7.67 7.25 7.57 6.30 8.49 6.23
## CDK14 3.72 6.66 5.32 4.72 2.41 3.83 3.09
## SEC61A1 211.29 241.03 244.31 266.36 229.05 265.54 204.54
## PPP1R12A 7.45 14.31 9.57 9.80 9.57 13.73 8.08
## RASGRF1 0.15 0.29 0.13 0.30 0.55 0.62 0.40
## CAMK2B 0.13 0.09 0.38 0.13 0.12 0.04 0.20
## CROCC 4.08 7.21 5.83 6.03 5.99 5.67 4.51
## POLR3E 21.01 26.84 17.93 27.21 25.30 23.85 20.86
## ATP2B4 49.55 67.41 70.97 75.79 45.85 59.71 31.55
## ZC3H11A 37.51 63.16 44.22 46.39 37.76 55.16 34.59
## RIOK2 32.21 31.83 27.13 38.58 41.13 39.32 35.62
## YIPF1 35.99 38.56 36.59 41.15 39.10 41.61 33.07
## NDC1 8.03 11.05 12.38 10.59 10.21 10.06 8.36
## DGKG 16.60 22.59 23.22 15.98 18.74 23.69 20.72
## FLYWCH1 33.64 40.95 29.58 29.85 33.98 32.19 35.27
## UNKL 13.52 14.15 9.47 12.54 11.94 16.36 11.52
## TBXAS1 8.78 8.69 10.80 10.98 10.13 7.65 11.73
## PARP12 22.44 28.03 24.09 19.23 20.51 22.18 19.01
## ALDH18A1 39.21 45.93 46.14 47.19 42.61 39.88 42.30
## TARBP1 6.96 10.97 11.84 11.82 7.82 8.52 7.42
## PET112 16.55 16.69 16.40 15.01 15.50 14.29 15.82
## MXD1 8.14 9.23 7.37 8.17 10.52 12.87 12.96
## CDK17 5.73 7.98 6.73 7.14 9.04 9.56 8.26
## DNAJC25 21.14 46.40 44.18 42.60 64.71 24.94 44.27
## SLC2A3 94.22 108.99 87.95 100.28 111.68 149.04 102.08
## PSD 2.25 3.09 2.49 1.37 0.98 1.56 2.05
## CTDP1 11.43 13.57 12.77 14.47 11.97 12.60 10.27
## YBX3 324.09 317.14 246.27 295.72 324.13 310.74 347.54
## STYK1 4.00 2.84 3.50 5.59 6.52 7.21 5.90
## WNK1 22.34 35.85 30.47 29.41 27.51 44.96 29.68
## CCAR1 29.40 42.04 39.26 45.22 49.74 42.28 30.88
## OGFR 58.18 61.20 56.14 73.50 64.17 56.31 54.03
## GNA15 16.54 14.32 10.62 5.64 5.10 5.06 9.32
## CREB3L3 0.01 0.03 0.05 0.01 0.01 0.08 0.07
## PIGV 23.36 22.28 16.46 17.96 16.98 21.01 21.43
## PTPRU 6.17 8.91 5.45 4.93 2.47 3.94 3.77
## SNRNP40 52.10 43.77 48.98 55.22 55.56 49.51 45.34
## RIMBP2 0.00 0.00 0.02 0.00 0.00 0.01 0.00
## COL11A1 1.10 1.02 1.07 1.15 1.08 0.99 2.08
## QSER1 7.42 14.87 11.81 11.07 11.92 14.83 10.30
## MPC1 27.47 26.39 23.90 24.92 32.78 25.86 37.34
## ACAA1 26.97 25.10 30.14 33.29 30.33 27.27 28.88
## BCAT1 22.29 33.80 33.05 24.67 25.59 27.47 26.34
## HDAC7 35.92 43.66 35.77 49.38 38.20 39.82 28.56
## LZTS1 0.01 0.06 0.01 0.02 0.01 0.00 0.05
## PRDM6 0.32 0.17 0.13 0.14 0.26 0.21 0.08
## WNT8A 0.00 0.00 0.00 0.00 0.00 0.00 0.02
## SPAG4 93.96 86.51 103.74 72.85 48.50 58.65 66.24
## NCKAP1 74.75 111.88 93.21 93.60 82.01 111.00 80.50
## MRPS35 56.74 53.46 56.92 52.16 64.17 58.62 62.90
## GUCY1B3 8.17 13.39 12.77 8.28 7.41 8.56 7.65
## SFSWAP 18.47 24.49 18.89 19.08 20.67 19.32 23.40
## TNK2 17.65 27.50 20.43 30.37 21.95 22.59 15.54
## MON2 4.45 8.21 7.38 6.43 4.97 7.74 6.02
## CDH3 0.09 0.32 0.18 0.17 0.59 0.12 0.37
## ARSF 0.00 0.00 0.02 0.00 0.00 0.00 0.00
## GPBP1 47.20 60.78 43.44 51.07 47.00 59.37 44.15
## DGAT2 15.30 16.52 17.47 14.32 10.12 11.07 8.96
## ZNF112 2.16 2.73 3.33 2.45 2.08 2.15 2.22
## CS 76.77 88.48 88.46 91.18 86.21 93.02 81.88
## LTK 0.16 0.23 0.19 0.25 0.30 0.24 0.13
## MRPS24 248.45 185.05 196.05 217.02 211.08 201.26 218.25
## ELMO2 38.74 43.03 41.11 38.78 36.69 40.90 42.71
## WAPAL 13.06 16.80 14.46 16.61 16.92 17.84 17.25
## VMP1 155.21 188.89 167.75 129.24 104.59 119.17 134.87
## APPBP2 7.78 10.90 9.95 8.06 10.31 11.97 9.76
## POLD1 21.14 22.43 36.77 49.66 27.11 23.36 13.17
## SEZ6 0.04 0.05 0.05 0.03 0.05 0.00 0.02
## EIF4B 106.78 151.40 98.78 111.44 131.70 137.91 131.55
## SLC6A16 0.06 0.17 0.12 0.17 0.13 0.06 0.14
## GLTSCR1 1.56 2.05 1.37 2.45 2.26 2.90 1.82
## SPHK2 6.24 6.91 6.67 6.67 5.82 7.00 7.02
## RPL18 1232.25 865.66 961.73 959.85 1030.91 970.21 1159.54
## CA11 5.66 4.59 3.07 3.26 4.96 3.80 6.56
## ISOC2 58.00 42.30 39.82 41.69 49.57 39.42 62.40
## U2AF2 80.64 79.82 95.26 101.89 101.76 99.05 90.55
## EPN1 81.30 86.27 76.13 99.13 76.04 85.61 66.73
## MED29 31.12 33.83 30.12 27.85 34.66 31.54 41.67
## AHRR 11.82 21.19 12.59 12.27 10.46 15.39 14.66
## GSC2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZNF275 4.11 5.95 4.06 3.90 5.23 6.24 6.66
## MTMR1 4.38 5.49 5.23 3.40 3.12 3.99 2.80
## GPC1 91.23 96.11 58.12 82.98 79.41 92.60 94.93
## ADCK1 2.90 3.01 2.79 3.30 2.21 2.38 2.71
## HAGH 42.37 42.17 38.34 36.37 32.17 32.08 37.88
## RNF4 37.73 44.45 53.59 47.69 54.53 54.79 52.56
## CASP8 18.29 29.27 22.73 20.09 19.52 20.25 22.62
## LIMCH1 0.92 1.32 1.58 0.97 0.78 1.15 0.94
## ASUN 40.36 44.23 44.17 58.27 48.84 50.94 33.23
## TM7SF3 27.85 35.55 38.07 25.12 32.96 30.37 32.08
## DLX3 1.07 1.95 1.30 0.86 0.78 0.55 1.06
## SPA17 12.69 11.73 12.04 10.36 10.02 9.12 10.88
## TSPAN32 0.11 0.02 0.00 0.01 0.07 0.01 0.13
## WISP2 1.61 1.20 1.16 0.85 1.12 1.10 1.66
## DMRT3 0.00 0.00 0.11 0.01 0.00 0.00 0.00
## ST3GAL6 4.74 5.73 8.53 8.12 5.14 6.19 3.99
## ATP2C2 0.45 0.80 0.84 0.79 0.89 0.53 0.63
## NGFR 0.24 1.10 0.15 0.26 0.35 0.20 3.18
## CDON 1.01 1.52 1.04 0.99 0.77 1.19 1.25
## TAF2 13.99 23.37 20.56 17.26 18.45 20.61 16.38
## HIPK2 23.35 43.45 26.42 31.02 23.85 45.50 24.56
## TNPO3 46.40 60.82 53.43 53.18 50.80 68.64 50.69
## MEF2BNB-MEF2B 8.45 7.78 4.99 7.99 9.10 6.82 6.61
## RFXANK 116.34 84.02 85.20 87.70 60.01 71.08 77.42
## TMEM161A 24.73 24.57 21.62 25.81 28.52 23.45 29.74
## LPAR2 4.23 6.88 2.37 4.43 5.77 6.38 5.36
## CTSA 233.00 264.53 258.52 258.23 312.77 261.70 294.07
## SUGP2 40.07 51.16 43.38 52.56 48.62 51.43 43.17
## SLC12A2 4.87 7.38 6.64 5.66 7.95 10.88 7.06
## SNX24 16.53 16.33 20.49 20.35 18.91 19.00 17.74
## EYA2 0.07 0.05 0.07 0.08 0.08 0.05 0.09
## CNN2 60.02 49.67 61.48 70.20 34.18 53.21 25.47
## ABCA7 2.51 4.96 4.03 5.50 2.65 3.96 2.61
## SNCAIP 0.44 0.36 0.52 0.47 0.16 0.25 0.81
## DDX20 12.10 13.32 13.39 15.14 15.79 16.64 14.29
## BTBD1 48.49 63.58 64.01 54.41 65.84 61.79 51.92
## FAR2 10.17 10.88 9.34 9.81 8.94 11.40 8.61
## BCAS1 0.55 0.54 0.47 0.34 0.49 0.35 0.58
## POU1F1 0.04 0.05 0.00 0.11 0.06 0.21 0.02
## CHI3L2 54.14 53.84 54.12 43.72 44.80 46.91 50.10
## SBNO2 52.55 64.49 54.85 68.56 49.36 60.83 44.05
## PMS1 8.18 10.57 7.54 8.73 9.62 7.97 11.26
## HMG20B 124.96 120.73 96.45 119.14 90.76 99.54 88.58
## CALCRL 0.12 0.25 0.21 0.11 0.14 0.30 0.06
## TAF11 12.65 13.98 13.93 13.99 14.14 13.78 13.39
## ANKS1A 1.73 2.97 2.07 2.15 1.40 2.06 1.30
## AP3D1 47.73 62.19 47.53 69.25 64.01 63.96 60.48
## ZNF76 10.18 13.38 12.62 11.92 10.76 12.04 9.16
## SLC9A3R2 4.99 4.44 3.48 4.18 2.42 3.60 2.07
## NTHL1 7.34 5.68 5.86 6.56 5.51 4.71 5.83
## UHRF1BP1 1.14 1.90 1.18 1.04 1.14 1.26 1.47
## GNAI3 77.45 86.23 101.51 79.65 93.26 97.56 76.53
## IPO5 153.10 208.90 160.97 157.83 147.06 173.64 182.20
## OAT 54.01 71.32 54.13 60.18 74.39 68.12 70.25
## WDR3 38.14 45.07 38.15 42.53 63.50 59.74 63.17
## PKN2 4.53 7.50 7.46 5.84 6.21 7.14 5.74
## WDR18 36.37 26.68 29.48 34.61 29.59 28.53 34.83
## TRAM2 16.00 21.84 19.77 24.55 18.39 24.52 17.06
## NTN1 0.17 0.37 0.13 0.18 0.10 0.19 0.25
## GLP2R 0.07 0.02 0.02 0.00 0.02 0.00 0.07
## MCM10 3.46 4.63 11.61 10.38 7.54 6.66 4.31
## DGKA 14.87 22.45 13.05 17.67 9.83 12.87 9.04
## ERBB3 0.22 0.37 1.19 0.29 0.24 0.20 0.39
## ROPN1 0.04 0.05 0.12 0.00 0.02 0.06 0.00
## ANKRD44 1.66 2.76 3.42 1.58 1.27 0.89 0.92
## KARS 186.65 174.99 175.94 190.53 202.18 190.56 198.95
## ADAT1 26.92 34.11 25.71 26.90 29.87 28.54 37.15
## PDIA5 15.21 25.20 14.19 14.85 16.12 12.53 17.44
## TBC1D22B 4.70 5.22 4.17 4.60 4.51 5.40 3.41
## NDUFB4 384.90 312.37 326.61 347.21 313.02 323.54 313.21
## SPEN 14.99 26.64 20.35 24.42 16.05 20.78 17.15
## MYLK 16.56 25.31 18.37 19.97 15.15 20.21 20.29
## ZC3H15 59.92 65.72 70.53 66.42 86.25 78.54 73.68
## MAP2K4 13.03 19.24 15.21 14.28 15.22 17.87 14.15
## TMEM206 17.03 17.43 15.68 19.08 22.41 23.95 22.13
## SNAP91 0.00 0.03 0.00 0.00 0.00 0.00 0.02
## SLK 8.78 15.45 11.81 10.91 14.07 16.10 11.48
## CYB5R4 8.16 10.10 10.73 9.14 11.08 11.36 9.85
## COL17A1 0.26 0.32 0.33 0.74 0.41 0.59 0.43
## GSTO2 1.95 2.56 2.16 2.22 4.21 2.81 4.75
## SEC61A2 9.99 11.12 11.41 10.16 10.54 12.25 11.47
## PRKCQ 0.01 0.04 0.00 0.00 0.00 0.00 0.00
## TLE2 1.08 0.57 0.46 0.48 0.72 0.64 1.00
## ASB1 180.41 170.17 131.79 210.02 198.63 181.89 221.54
## FAM107B 4.95 6.96 6.42 5.21 6.30 8.65 8.60
## ME1 0.11 0.08 0.06 0.05 0.04 0.08 0.17
## TBC1D1 29.62 36.48 34.52 35.76 25.91 29.62 27.45
## CDK13 10.02 14.22 10.30 11.93 12.77 15.62 12.69
## MTHFD2 138.44 136.28 137.57 116.56 158.44 140.61 190.46
## SLC9A7 7.77 11.81 9.10 7.69 6.54 9.33 8.35
## FOXJ2 12.10 18.02 12.13 14.80 14.75 19.14 14.86
## YBX1 704.88 652.36 669.19 782.29 847.29 810.23 685.08
## PDE4A 2.09 3.37 2.15 2.56 1.25 2.32 1.32
## PPP2R5A 25.75 30.60 25.92 22.68 24.55 25.67 22.42
## CTNNA2 0.65 0.66 0.46 0.67 0.71 0.42 0.79
## ELAVL1 36.14 36.53 37.43 41.78 37.27 39.49 34.30
## TIE1 1.09 2.08 1.98 2.11 1.30 1.87 1.23
## DIP2B 4.72 8.07 6.45 6.87 7.73 9.99 7.10
## SMARCD1 29.28 33.95 31.56 32.04 32.34 33.23 31.04
## KDM4A 9.62 15.90 12.92 11.69 9.92 13.77 8.99
## NFYC 45.55 44.30 44.87 42.49 44.27 42.50 44.07
## ZMYND12 0.04 0.09 0.00 0.10 0.02 0.00 0.12
## SLC9A3 0.74 1.10 0.41 0.46 0.38 0.41 0.65
## NGEF 1.35 1.34 1.70 0.82 1.05 0.64 1.59
## ASPM 3.27 5.30 5.16 4.48 2.57 3.36 3.04
## CD84 0.00 0.00 0.01 0.00 0.05 0.00 0.01
## ELOVL1 144.34 118.95 169.01 177.02 144.59 159.99 115.60
## SPI1 0.38 0.18 0.39 0.54 0.92 1.21 0.72
## ZNRD1 35.87 26.87 24.64 22.89 28.79 28.38 39.43
## MPPED2 0.16 0.47 0.03 0.13 0.08 0.10 0.23
## CLDN18 0.06 0.11 0.08 0.09 0.10 0.13 0.05
## ZBTB11 4.15 6.53 6.00 5.07 6.32 6.34 6.40
## ATXN3 19.30 20.35 17.70 15.36 16.48 20.01 22.75
## GOLGA5 26.43 33.38 27.66 27.52 26.86 29.19 26.21
## FGFR2 0.09 0.11 0.03 0.02 0.07 0.04 0.03
## LRRC40 8.94 9.98 10.95 9.12 12.12 10.86 8.68
## ISOC1 13.11 16.07 12.96 14.26 20.44 16.56 19.34
## EML1 64.08 89.65 72.97 53.79 42.30 60.00 55.47
## TRMT11 15.77 19.82 16.14 14.65 13.93 16.74 17.41
## THUMPD1 13.22 19.36 16.52 16.17 19.34 19.25 20.29
## MSANTD3 81.86 97.55 110.87 89.34 85.13 87.72 78.01
## KIF26A 0.00 0.01 0.00 0.00 0.00 0.01 0.00
## ATG2B 2.60 4.50 3.46 3.22 2.62 4.97 3.47
## ARFGEF1 13.83 21.54 13.63 17.19 12.93 17.52 12.07
## ACSM2B 0.00 0.00 0.00 0.00 0.00 0.01 0.01
## ZFAT 3.66 4.99 3.50 4.91 2.81 3.84 2.41
## MTFR1 18.47 25.00 17.82 21.01 24.98 23.19 24.34
## STAG3 2.37 3.37 3.57 3.06 2.79 2.33 2.35
## FECH 12.95 16.01 15.36 12.81 19.15 15.78 17.15
## MYO9A 3.15 6.51 5.36 4.71 3.65 6.99 3.67
## DDX3Y 2.17 3.67 2.99 2.19 2.50 3.35 2.70
## PFKP 259.80 275.55 282.80 290.87 242.55 264.15 245.94
## IDI1 22.99 27.75 28.00 24.68 28.20 29.71 29.97
## SP100 41.81 55.45 48.96 35.00 36.28 43.38 41.48
## KLF6 26.20 25.91 26.31 28.72 37.99 39.62 24.66
## PPAP2A 16.57 18.48 16.69 17.00 14.64 16.43 15.53
## NEO1 2.85 5.81 3.83 2.96 1.94 4.49 3.01
## TRAM1 78.46 100.58 109.49 89.34 86.80 122.24 75.34
## PHKA1 4.53 6.61 5.06 5.75 4.51 5.50 4.43
## TNFRSF1A 91.72 93.18 95.30 95.62 79.56 94.18 64.60
## CACNB1 6.28 8.66 7.93 8.88 7.21 7.20 5.59
## EVI5 2.42 4.74 3.88 2.85 2.85 4.10 2.49
## STOML1 17.23 13.42 18.24 17.47 16.24 12.41 20.72
## PKM 2236.49 2123.76 2812.89 2668.99 2241.43 2563.37 1783.25
## DHX29 15.52 21.71 18.85 18.79 21.68 22.78 20.79
## DNTTIP2 32.25 36.40 30.57 38.17 43.65 35.03 43.72
## METTL22 12.98 14.17 12.68 11.52 12.07 13.38 14.26
## TP53BP1 11.78 20.91 18.22 16.04 15.94 18.03 16.13
## TRO 2.99 5.04 4.58 4.49 3.26 3.10 4.00
## RRP15 12.71 12.54 15.88 14.55 17.31 14.21 16.21
## RHOA 380.42 396.66 389.88 399.02 424.67 443.54 349.08
## DHX8 22.20 27.88 23.25 30.28 25.73 27.20 22.77
## PRKCZ 0.29 0.52 0.28 0.43 0.19 0.22 0.43
## ZFY 0.40 0.28 0.36 0.52 0.43 0.42 0.40
## IARS2 37.00 51.93 50.24 51.10 40.32 46.56 29.66
## SYT1 0.94 1.31 0.92 0.71 0.45 0.80 0.51
## NAV3 8.04 8.48 9.90 13.19 13.00 14.37 10.28
## IDH3G 50.87 53.23 57.00 55.16 50.63 47.47 43.50
## ROGDI 3.81 5.32 6.46 5.06 5.39 3.97 5.56
## PDZD4 0.20 0.12 0.04 0.28 0.19 0.14 0.15
## ATP2B3 0.01 0.07 0.02 0.02 0.00 0.07 0.24
## ROCK1 14.76 25.05 19.96 18.95 19.02 23.39 15.77
## CBFB 42.72 64.96 52.75 50.80 56.46 58.53 47.28
## PDK3 7.00 8.33 10.52 8.45 6.58 8.87 6.10
## HYAL2 31.13 28.46 31.27 31.26 28.03 28.92 31.22
## HDAC4 9.00 14.25 8.79 7.93 5.51 9.21 6.65
## RASSF1 53.18 32.39 49.26 71.16 50.49 59.62 38.64
## FGFR3 0.11 0.12 0.06 0.15 0.07 0.19 0.11
## IFI35 30.29 28.12 28.32 18.82 23.75 17.81 36.09
## HEATR6 9.21 12.22 10.45 10.05 9.67 10.22 11.76
## COASY 58.20 58.57 58.23 61.33 46.66 52.19 46.24
## PLEKHH3 11.69 12.42 13.55 13.20 8.89 9.91 7.57
## MEF2A 15.36 23.32 23.91 15.73 16.83 20.98 18.31
## OTUD5 49.07 60.75 51.25 51.22 45.57 48.80 43.67
## TFE3 69.35 67.97 59.84 81.67 62.63 82.49 58.31
## TBC1D25 8.59 13.46 10.40 11.36 10.03 11.52 7.29
## ACSL4 31.93 50.66 45.76 40.58 40.39 45.90 29.68
## INPP5A 11.15 12.59 10.44 12.97 11.70 13.18 9.14
## GPKOW 27.68 29.57 24.73 25.88 24.42 24.42 23.68
## GRIPAP1 12.27 22.10 16.53 16.99 11.39 13.37 13.30
## FTSJ1 137.01 119.41 133.72 131.39 114.87 110.99 110.40
## PRR11 10.75 14.98 14.20 12.67 7.72 10.49 8.27
## REEP1 1.11 1.55 1.22 0.71 0.77 0.73 1.29
## ATP11A 1.12 2.19 2.07 1.80 1.09 1.90 0.97
## POLR1A 4.31 7.00 6.06 6.82 6.98 8.17 6.57
## LAPTM4A 266.88 288.48 235.27 249.15 301.98 293.46 331.57
## TTC7A 8.65 10.48 10.85 13.80 8.84 11.51 7.92
## IP6K2 68.71 70.37 72.00 73.48 69.35 72.84 62.95
## STON1-GTF2A1L 0.67 0.62 0.00 0.00 0.81 0.21 0.37
## SRBD1 3.28 5.97 5.42 5.77 4.82 4.53 4.47
## CYFIP1 37.35 48.42 42.50 41.65 35.73 41.88 33.36
## KIF2A 10.76 15.66 15.59 13.76 16.09 19.52 13.56
## RASGRP2 0.21 0.19 0.38 0.14 0.42 0.22 0.51
## PSME4 25.97 34.66 25.10 32.56 30.55 35.28 30.37
## IFT80 8.59 20.16 15.45 12.57 9.29 9.99 11.02
## SIRT2 38.13 33.35 34.88 35.91 32.86 33.24 36.45
## ERLEC1 52.58 72.45 54.04 45.99 41.79 49.89 47.10
## PPP2R5B 59.24 57.99 78.29 69.58 43.93 54.94 35.35
## PYGM 0.80 1.04 0.91 0.96 1.46 1.20 0.78
## PAGE1 1.48 0.57 0.66 0.95 1.04 0.81 0.75
## PITX1 10.97 10.37 7.94 9.83 9.44 7.86 9.45
## TRPC7 0.00 0.00 0.00 0.00 0.00 0.00 0.10
## MAST4 4.33 7.06 6.05 3.97 3.73 5.91 4.35
## GPR116 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## SDK2 0.15 0.10 0.07 0.08 0.09 0.03 0.13
## ADAM7 0.18 0.20 0.15 0.18 0.41 0.21 0.86
## NUP133 9.91 13.80 10.33 10.87 11.19 10.44 10.89
## NUCKS1 64.28 70.54 58.88 65.80 54.84 56.03 65.64
## VPS35 38.78 48.44 48.29 52.63 47.00 54.10 44.42
## DNAJA2 53.09 57.17 50.35 56.71 63.51 64.06 64.92
## BCL3 35.90 45.00 26.36 29.94 30.92 28.13 41.19
## KCNAB2 7.42 8.93 5.64 7.04 5.99 6.62 8.00
## ABCC9 1.72 2.29 2.30 2.29 3.12 3.23 3.21
## GAL 0.00 0.55 0.00 0.04 0.00 0.05 0.04
## CLEC2D 2.79 5.37 3.49 3.12 4.66 3.81 7.44
## FUNDC1 23.24 25.33 26.30 24.82 24.62 19.72 21.57
## MAOB 0.05 0.07 0.02 0.02 0.01 0.00 0.00
## RORA 15.27 26.58 15.75 11.27 12.76 16.90 15.09
## DRD4 0.53 0.56 0.21 0.65 0.75 1.11 0.99
## TGFBR3 0.68 1.05 1.05 0.87 1.14 1.36 1.18
## KIAA1107 0.32 0.80 0.31 0.29 0.15 0.29 0.29
## PLA2G10 0.10 0.09 0.00 0.10 0.11 0.12 0.18
## HES2 0.44 0.27 0.10 0.34 0.57 0.66 0.76
## ATP1B3 200.23 195.42 218.08 273.96 223.97 256.33 178.90
## NEDD4 16.44 23.67 22.78 22.45 20.46 27.71 16.84
## PIGB 9.65 10.75 12.50 9.57 8.39 8.88 8.87
## MAPK6 35.05 50.85 48.83 41.60 68.94 68.55 64.06
## GNB5 34.01 40.48 39.52 32.57 28.95 35.07 31.22
## RAB27A 34.35 45.80 48.06 38.47 33.91 37.39 33.94
## CECR5 39.15 37.35 50.48 52.90 39.58 39.81 33.76
## UFD1L 129.36 115.94 139.98 140.70 133.77 143.23 113.36
## LRP6 1.90 4.13 3.36 2.48 2.29 3.71 2.72
## GUCY2C 0.07 0.05 0.05 0.03 0.08 0.08 0.11
## SCT 0.13 0.00 0.18 0.00 0.44 0.00 0.14
## PHRF1 9.84 13.78 11.97 16.62 15.11 15.70 11.67
## IKBKAP 16.17 28.85 22.26 21.70 20.50 20.91 19.16
## NUCB2 122.28 139.46 125.49 127.84 118.38 112.27 123.82
## PFN2 210.81 225.73 240.57 217.67 217.61 259.40 200.50
## PTPN3 7.71 13.83 10.46 8.57 6.83 9.88 6.00
## SPTB 0.06 0.10 0.08 0.07 0.08 0.04 0.10
## DAPP1 0.27 0.49 0.29 0.22 0.41 0.63 0.58
## FGF10 0.01 0.01 0.02 0.00 0.05 0.00 0.00
## SLC44A1 9.40 14.62 11.47 10.20 7.58 11.77 7.87
## TMEM260 4.94 6.03 4.52 4.45 5.37 4.95 5.27
## SMG6 31.84 37.45 30.16 32.16 28.00 26.61 33.90
## EXOC5 18.53 28.24 28.12 21.29 24.34 27.58 17.27
## CLTCL1 1.43 2.16 2.05 2.22 1.36 1.82 1.30
## FGF22 0.36 0.51 0.45 0.09 0.41 0.26 0.49
## FSTL3 5.48 7.07 5.17 5.09 5.74 4.38 6.71
## DGCR2 18.42 23.17 17.37 22.11 19.51 22.56 19.27
## RNF126 91.39 70.93 91.86 93.20 81.34 82.07 74.42
## MNT 7.65 10.73 7.95 9.44 10.58 9.77 11.18
## ZXDC 7.93 12.18 9.16 9.18 8.87 8.81 8.89
## JMJD6 96.92 81.84 100.41 117.45 89.78 104.81 72.07
## POLB 28.09 26.20 26.01 22.90 28.23 23.28 35.56
## ST6GALNAC1 0.12 0.27 0.14 0.04 0.05 0.03 0.00
## WIPI1 66.06 82.27 48.31 55.54 66.38 70.20 91.59
## FRMPD1 0.07 0.12 0.10 0.06 0.05 0.08 0.12
## GBA2 40.60 58.36 56.38 61.57 54.99 56.19 42.57
## NDST1 28.76 38.37 37.81 39.54 29.94 43.32 26.63
## ASNS 162.14 172.70 87.56 79.81 186.56 137.74 321.17
## AP3M2 14.90 18.47 18.33 14.85 14.97 14.97 16.22
## CNGB1 0.03 0.05 0.02 0.20 0.00 0.07 0.12
## ST6GALNAC2 0.36 0.48 0.46 0.31 0.35 0.28 0.59
## CHAT 0.03 0.00 0.00 0.00 0.02 0.00 0.00
## PABPC1 716.25 937.40 732.74 791.51 891.04 821.77 991.43
## TESK2 1.83 2.29 1.75 2.15 1.73 2.23 1.59
## C16orf80 30.32 26.17 32.71 37.34 37.58 33.49 34.54
## CSNK2A2 61.82 76.96 56.53 69.00 74.09 77.15 70.49
## PTPN21 5.30 7.62 5.73 6.70 6.54 8.51 5.73
## EIF2B3 32.59 33.50 32.86 34.27 29.60 29.44 31.15
## CAMK2A 6.88 14.91 7.57 7.37 3.05 4.54 4.86
## TCOF1 24.68 30.83 30.50 38.49 32.48 31.05 21.34
## CDC42 154.26 159.08 194.36 173.27 187.48 199.39 156.66
## OSBPL3 7.24 11.37 11.39 11.28 12.26 13.02 10.23
## EPHA8 0.02 0.03 0.08 0.02 0.02 0.01 0.06
## SLC12A3 0.10 0.06 0.00 0.04 0.05 0.01 0.10
## RAD18 6.31 8.68 9.69 9.93 9.63 9.33 6.32
## ATP2B1 14.57 27.08 21.43 20.86 17.69 20.85 10.81
## TRPM5 0.04 0.04 0.00 0.01 0.00 0.01 0.02
## NCK2 16.12 18.24 17.32 18.64 11.21 18.05 12.77
## MAP4K4 63.27 93.85 77.68 80.00 61.02 91.60 54.49
## MGAT4A 0.08 0.04 0.43 0.04 0.06 0.02 0.18
## RPL31 3248.63 2670.34 2745.04 2690.06 2545.41 2575.33 3244.31
## WDR1 322.50 337.62 316.32 336.36 316.69 319.40 288.45
## SNX13 6.35 12.53 9.75 7.60 8.46 11.72 11.59
## MS4A12 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ARHGAP10 13.83 15.79 13.33 15.73 11.23 15.42 10.59
## RPS6KA2 14.03 19.52 8.36 9.51 10.85 14.12 20.82
## ING3 10.73 11.46 15.26 10.35 11.11 12.28 9.80
## VASH1 1.92 3.79 3.19 3.09 1.96 2.16 1.38
## LMCD1 4.75 3.18 5.03 3.50 4.76 3.67 3.97
## WBSCR22 207.42 200.17 189.48 217.25 209.08 201.94 190.28
## SEL1L 20.94 35.00 30.59 22.75 26.07 33.38 29.25
## TRIP13 30.42 27.95 40.81 38.76 31.75 33.40 37.43
## ATP6AP1 73.49 74.85 71.77 79.56 68.60 81.36 64.00
## TCF3 53.39 59.23 53.84 70.46 54.06 59.82 46.94
## TRIB2 14.67 19.25 19.77 14.99 15.81 15.25 11.44
## DAZAP1 98.82 110.77 89.79 123.06 116.01 102.64 119.46
## MBD3 57.16 61.62 50.50 84.03 60.07 63.34 56.58
## PRLH 1.91 3.69 1.41 1.00 0.28 1.53 1.85
## HLTF 14.04 22.91 19.72 15.86 14.46 16.84 14.75
## FAM50A 186.03 183.12 179.20 213.03 188.37 173.19 163.73
## FAM3A 68.08 54.71 61.39 60.62 52.91 53.82 51.99
## CPSF1 39.07 48.10 46.00 64.40 43.52 47.11 32.97
## MYO3B 0.26 0.37 0.35 0.33 0.24 0.38 0.41
## CYBRD1 27.98 39.48 27.79 29.19 33.21 43.22 31.04
## CDH19 0.03 0.03 0.01 0.02 0.01 0.08 0.07
## PDCD2 96.78 86.31 91.40 98.52 88.35 86.66 82.43
## SLC6A15 9.84 12.82 8.42 9.38 13.18 11.86 15.43
## RDH11 89.52 111.00 103.39 107.45 98.88 103.23 108.75
## PRKACA 66.37 81.72 75.01 80.08 55.14 79.63 61.89
## LPHN1 5.35 8.06 5.91 6.87 3.70 6.02 3.42
## SPP2 0.00 0.00 0.14 0.00 0.09 0.11 0.00
## ACTN1 172.30 204.20 172.44 153.30 154.93 160.28 182.90
## ZFYVE26 3.89 7.58 4.71 4.74 5.34 5.93 4.53
## RPS6KA6 0.39 0.70 0.64 0.50 0.27 0.49 0.26
## EPN2 31.86 39.29 36.24 32.32 25.42 35.66 23.39
## PTPN18 39.19 47.19 39.59 35.63 33.37 34.25 41.43
## LIMS2 0.13 0.29 0.16 0.09 0.19 0.14 0.31
## ASIC4 0.54 0.88 0.24 0.39 0.53 0.44 0.52
## SPEG 47.62 63.29 54.21 59.00 38.49 43.55 38.95
## LNX1 5.56 7.02 7.38 4.47 6.07 5.14 5.89
## ALDH3A2 29.33 43.40 35.90 37.20 36.73 39.99 36.76
## TFRC 132.52 178.22 172.01 177.04 193.05 226.86 164.12
## SREBF1 49.22 62.90 52.68 69.29 45.08 61.32 48.43
## TRPC5 0.00 0.02 0.02 0.02 0.02 0.01 0.00
## AFF4 13.80 24.87 22.67 17.24 20.55 29.40 21.06
## UBE2D1 17.94 22.57 21.77 15.93 30.99 25.44 22.74
## MPP5 12.89 19.28 17.21 14.45 16.19 19.00 14.48
## RHOBTB1 4.42 6.57 3.37 3.13 3.77 3.42 4.46
## SMC1A 6.37 12.60 17.70 14.10 8.56 13.71 5.99
## HSD17B10 115.19 88.51 106.45 113.06 130.41 109.11 101.81
## MARK2 9.68 12.94 11.22 11.78 10.24 14.24 8.17
## HMMR 8.24 10.27 14.39 11.91 10.98 10.27 9.92
## CHFR 0.05 0.14 0.09 0.04 0.00 0.07 0.09
## TRHDE 0.01 0.00 0.00 0.01 0.00 0.01 0.01
## P4HA2 269.19 326.10 340.85 320.34 210.40 262.80 218.62
## FCGR2B 0.01 0.07 0.04 0.04 0.00 0.02 0.01
## NFATC3 7.81 13.42 6.72 8.68 8.52 11.13 9.00
## TRNT1 14.26 16.57 15.80 16.59 18.96 18.53 20.13
## ACADVL 473.60 643.15 753.70 692.09 518.84 457.32 396.69
## STK10 27.50 41.35 28.97 36.41 33.64 40.05 31.27
## FBXW11 18.57 26.12 21.15 19.94 17.80 24.43 19.98
## ACAP1 22.48 19.83 24.10 18.27 16.86 15.94 28.55
## CRMP1 8.59 21.25 13.80 13.42 12.42 18.23 11.66
## EVC 61.83 73.58 58.93 58.75 59.43 67.81 77.76
## DERL2 96.76 77.29 89.66 93.70 96.24 92.77 78.70
## SIDT1 0.25 0.42 0.32 0.30 0.54 0.36 0.45
## NDE1 23.35 31.40 18.42 20.32 19.40 25.63 21.93
## MRVI1 0.14 0.10 0.13 0.09 0.15 0.19 0.21
## TMEM38A 3.19 3.09 2.79 4.37 2.91 3.91 2.08
## AP1M1 78.04 69.06 76.97 90.90 63.63 78.37 53.19
## PVR 34.10 34.03 37.17 54.08 62.80 60.79 46.82
## IKBKG 37.87 38.60 40.56 46.90 39.77 41.21 38.33
## XRCC1 25.49 29.42 25.96 24.73 17.70 20.29 16.55
## SCARB1 29.69 38.06 31.86 31.41 31.24 30.43 30.99
## CYP2W1 0.00 0.08 0.00 0.01 0.01 0.05 0.04
## MCM2 25.03 26.83 45.12 45.86 38.10 30.72 25.91
## MOV10L1 0.45 0.58 0.63 0.16 0.53 0.26 1.58
## PANX2 1.54 2.50 1.28 1.83 2.02 2.01 1.91
## SELO 14.81 14.71 13.62 18.28 16.63 15.55 14.01
## TP63 0.08 0.14 0.11 0.07 0.03 0.02 0.05
## ALPK1 4.14 7.51 4.28 3.41 3.57 4.47 6.26
## LLGL2 0.95 0.46 0.83 0.79 0.47 0.54 0.63
## PDE8A 28.01 45.93 37.67 36.60 32.12 36.53 30.77
## CLCN4 1.38 1.69 1.72 1.36 1.65 1.43 1.67
## NLE1 12.63 10.23 11.58 11.21 13.82 12.76 15.70
## SDHA 90.00 112.85 93.29 82.61 46.16 61.73 57.59
## SMARCE1 97.62 106.50 106.79 100.20 108.38 108.37 107.81
## FNDC8 0.17 0.23 0.04 0.17 0.42 0.28 0.43
## GSDMB 1.56 5.11 2.18 3.24 1.69 2.29 2.46
## KDM5A 6.87 12.72 10.33 9.09 8.19 12.14 10.53
## ADAM11 0.49 0.50 0.35 0.27 0.29 0.27 0.55
## PPP2R3A 4.59 7.39 6.42 6.04 5.84 8.91 4.99
## FERMT2 19.09 21.96 25.38 23.31 21.76 24.09 14.79
## ABCB11 0.01 0.03 0.03 0.02 0.01 0.04 0.03
## DHRS9 0.29 0.38 0.47 0.20 0.21 0.38 0.13
## CD5L 0.76 0.96 0.90 0.49 0.61 0.78 0.83
## PTGS2 57.95 96.96 59.02 45.00 28.62 46.85 27.83
## IGF2BP2 18.12 23.82 18.01 23.05 16.36 23.79 15.17
## MAP3K13 39.55 35.31 36.36 30.07 36.37 35.25 40.30
## ST6GAL1 0.08 0.08 0.00 0.17 0.00 0.01 0.08
## TBX21 0.03 0.02 0.03 0.05 0.05 0.03 0.02
## FRY 0.50 0.75 0.54 0.48 0.43 0.19 0.34
## PICALM 40.83 50.36 55.33 57.09 50.34 59.90 43.30
## NSF 26.88 36.75 36.15 31.73 28.07 33.94 28.08
## GLI2 4.98 9.23 7.10 6.94 3.03 5.53 3.24
## CLASP1 9.70 16.50 13.55 12.53 8.79 13.74 10.02
## MRPS34 52.95 38.29 50.35 57.09 46.54 40.29 43.17
## NOTCH3 61.96 89.76 41.64 53.16 38.83 63.79 65.03
## CLNS1A 41.77 42.04 46.99 50.49 46.29 46.77 36.26
## PPP2R2C 0.16 0.23 0.15 0.09 0.08 0.07 0.22
## TEAD2 1.92 2.29 2.10 2.85 1.74 1.80 1.35
## EED 12.54 14.63 15.99 16.93 13.73 15.28 11.64
## CDHR2 0.50 0.70 0.51 0.79 0.13 0.63 0.08
## SNCB 0.27 0.20 0.27 0.38 0.06 0.25 0.46
## TSG101 93.20 102.01 101.78 83.20 86.40 87.19 87.51
## C17orf85 10.34 14.02 14.24 13.29 14.39 12.55 15.58
## ATP2A3 2.54 3.82 2.35 2.98 2.89 3.30 4.03
## CA12 134.85 190.15 210.13 149.92 104.98 162.58 124.07
## MGLL 116.34 117.87 104.85 130.30 95.02 135.29 99.15
## NTN4 3.10 4.86 1.49 1.49 2.56 2.67 3.13
## BCS1L 56.46 60.15 57.72 67.10 78.87 63.91 70.37
## NUAK1 1.18 1.92 1.01 0.98 0.90 1.02 1.08
## DPP8 14.61 23.33 19.53 14.00 15.81 21.67 18.77
## SLC24A1 2.97 4.15 2.88 1.91 2.01 3.77 5.01
## ZNF532 13.44 22.51 17.23 10.96 14.26 17.69 16.46
## SCARF1 0.66 0.92 0.40 0.42 0.62 0.39 0.83
## LMAN1 72.63 119.24 107.66 88.71 89.71 106.58 77.15
## PTPLAD1 47.70 56.58 56.65 52.47 53.21 59.57 50.45
## IPCEF1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZZEF1 7.05 11.37 9.60 9.32 7.92 10.74 8.33
## NOX3 0.33 0.41 0.17 0.32 0.28 0.24 0.31
## ENO1 2675.59 2347.31 3264.30 2886.37 2727.33 2910.57 2188.86
## SLC12A1 0.00 0.02 0.01 0.07 0.00 0.08 0.01
## C19orf10 304.17 239.41 261.12 263.89 238.58 248.90 242.01
## ANO8 8.27 10.64 10.33 10.35 5.23 7.78 6.51
## TUBE1 31.22 37.55 26.89 23.66 24.74 24.98 43.93
## ARHGEF10L 8.52 11.43 8.42 9.12 5.37 7.40 5.99
## TXK 0.00 0.00 0.04 0.03 0.03 0.09 0.00
## WSCD2 0.00 0.01 0.02 0.00 0.01 0.00 0.03
## KCNQ2 0.02 0.06 0.09 0.06 0.14 0.10 0.01
## TACR2 2.15 2.75 2.10 2.58 2.45 4.52 1.97
## ACTR6 11.75 15.25 10.59 10.24 12.58 13.19 13.41
## TIPIN 24.72 23.02 32.93 38.53 41.43 34.30 35.07
## SRI 196.84 164.65 174.29 175.29 152.80 151.41 143.79
## EIF4G3 22.87 38.81 30.75 27.50 20.55 31.05 21.79
## NUP37 37.95 36.72 41.98 35.48 41.26 37.81 41.72
## SEMA3A 6.24 10.25 8.59 5.25 8.00 7.45 9.13
## GTSE1 7.97 10.17 18.29 17.67 8.26 9.25 6.25
## SEMA3C 9.93 15.34 17.13 14.84 12.35 16.97 13.92
## TTC38 12.39 11.48 12.56 12.52 12.35 13.55 11.32
## ACAT1 20.77 23.51 20.60 20.56 22.18 22.55 24.51
## GRAMD4 4.27 5.49 2.49 6.14 4.08 5.41 4.16
## CELSR1 8.20 10.42 8.15 9.49 7.03 7.61 7.95
## WNT8B 0.03 0.04 0.00 0.01 0.00 0.00 0.05
## ZNF638 45.40 78.57 48.28 62.85 51.23 56.70 54.89
## SLC25A40 6.91 7.41 9.26 8.07 8.09 7.73 5.69
## TIMM21 36.97 38.48 54.24 46.60 44.68 38.89 33.99
## ADD2 0.17 0.24 0.16 0.15 0.19 0.32 0.15
## FGF4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RASAL2 1.46 2.68 2.06 2.17 2.10 3.24 1.85
## VPS9D1 8.66 12.02 10.40 10.12 9.21 8.44 8.71
## ZNF37A 4.06 6.50 5.48 4.33 4.12 5.63 4.33
## MARK3 51.44 63.03 49.84 53.14 50.10 52.76 54.24
## SLC25A3 291.09 258.28 250.56 283.64 279.33 278.39 285.37
## FNDC3B 23.85 37.33 32.45 22.85 22.25 28.58 30.55
## FOSL2 52.05 73.16 53.46 55.20 45.16 64.28 51.10
## CACNG5 0.00 0.00 0.00 0.04 0.05 0.00 0.00
## CACNG4 0.01 0.00 0.00 0.00 0.00 0.00 0.00
## FRYL 7.63 12.59 11.99 12.77 9.03 13.37 8.48
## TMEM131 17.69 25.99 21.15 20.78 18.96 27.02 19.65
## FSCN1 92.31 91.09 97.10 105.73 72.74 78.88 76.45
## ACTB 3251.67 2767.12 2997.70 3481.29 2765.57 2547.08 2384.61
## MOCOS 9.03 9.22 4.12 5.29 6.96 5.51 14.76
## PLD1 6.63 8.46 4.02 4.15 3.58 3.78 9.75
## ATP12A 0.02 0.01 0.02 0.00 0.02 0.00 0.01
## WDR62 4.93 6.12 8.94 11.93 7.88 7.58 5.17
## DLG1 18.44 29.44 25.68 24.82 16.42 28.41 21.83
## RAB7A 188.48 218.33 224.72 227.30 263.39 279.61 237.03
## BCAP29 73.01 92.10 98.80 81.45 70.79 91.58 56.80
## SEC31B 1.34 2.91 2.89 2.38 1.29 1.79 1.58
## SART3 17.45 23.79 21.88 19.68 22.30 21.59 24.64
## ARHGAP15 1.80 2.03 2.09 1.84 1.62 1.46 1.84
## TUBA3D 0.06 0.09 0.05 0.20 0.10 0.07 0.08
## PAX2 0.05 0.01 0.00 0.00 0.02 0.01 0.00
## EXOSC7 51.09 50.09 42.47 55.45 54.67 52.40 65.06
## KIFAP3 10.58 13.92 13.76 13.20 8.86 11.92 8.45
## MKRN2 28.54 30.02 24.96 26.19 30.79 33.24 38.95
## MCM6 28.88 35.51 45.71 52.73 33.54 30.23 35.98
## REXO2 59.69 58.42 65.06 62.84 62.53 61.60 60.86
## RBM7 9.20 13.04 10.14 9.43 11.11 10.75 11.06
## RBMS2 1.95 2.42 1.73 1.74 1.64 1.93 1.47
## BAZ2A 12.34 23.36 16.03 15.67 12.88 22.48 13.14
## PTPN23 11.97 16.65 13.14 17.56 15.53 19.87 15.21
## MLH1 18.15 21.27 22.88 18.38 22.37 19.10 26.07
## UNG 24.17 23.65 32.14 31.93 27.65 23.57 24.79
## FMO4 1.52 2.05 1.39 1.52 1.49 1.09 1.66
## KLHL20 6.36 9.43 6.90 7.26 6.74 8.69 6.88
## RGS11 0.00 0.05 0.19 0.06 0.02 0.02 0.03
## SLC46A1 3.78 5.82 3.53 9.07 4.84 6.13 6.33
## PLXNA2 3.43 5.39 5.43 5.73 2.93 3.73 2.56
## SPAG5 12.57 17.19 23.01 20.27 14.45 15.74 11.52
## ANKRD13A 40.68 45.64 52.43 58.94 42.95 57.51 42.84
## TPD52 27.84 38.98 54.45 39.73 37.61 32.61 24.06
## ACACB 2.09 3.02 2.09 2.05 1.06 2.11 1.46
## TRAF4 27.21 26.57 25.32 35.24 36.35 32.94 37.32
## PAG1 5.66 9.64 7.31 6.13 6.62 12.44 5.88
## GPATCH1 4.42 6.86 4.77 5.84 5.09 5.26 4.96
## ICAM3 25.24 18.71 17.56 20.82 18.86 20.50 16.44
## NT5C2 35.40 40.24 33.71 32.24 37.65 45.10 38.56
## MCAM 25.58 27.43 27.83 30.36 24.08 27.27 25.52
## GPC4 0.01 0.07 0.02 0.00 0.02 0.01 0.05
## MBNL3 0.09 0.18 0.25 0.14 0.12 0.14 0.23
## CAMSAP3 0.16 0.08 0.21 0.14 0.24 0.11 0.06
## RAP1GAP 1.06 1.40 0.62 0.42 0.94 0.69 1.50
## XAB2 39.89 38.99 29.44 35.43 38.20 37.10 40.31
## ARHGEF1 51.66 54.89 56.39 80.39 51.23 54.87 34.63
## STXBP2 3.88 4.56 4.17 5.40 5.28 3.93 4.06
## MAP2K7 11.91 15.17 14.52 18.07 14.26 17.99 10.84
## NMRK2 0.05 0.00 0.07 0.04 0.00 0.00 0.06
## DGKD 8.87 14.54 9.27 10.39 9.87 11.08 10.97
## CTTNBP2 3.28 4.52 4.48 4.89 3.58 4.10 3.63
## ACTL6B 0.03 0.00 0.00 0.00 0.00 0.00 0.03
## RARB 3.22 4.09 5.66 4.84 4.14 5.25 3.17
## TOP2B 30.49 53.56 33.09 32.06 31.86 36.30 30.55
## TM9SF3 50.16 78.37 63.59 59.95 72.05 87.53 54.73
## NFKB2 91.22 110.72 73.70 78.43 73.06 78.19 93.50
## UBE2T 36.00 27.23 61.45 51.05 41.30 33.85 28.71
## PPP1R12B 1.24 2.75 1.72 2.11 1.34 1.77 1.18
## DNAJC10 35.35 51.10 44.53 41.15 41.92 43.89 44.14
## GTF3C1 15.46 24.77 16.90 25.52 19.02 24.34 15.26
## IL4R 4.31 4.95 4.56 2.29 2.09 3.85 4.03
## USP33 19.03 25.16 20.67 19.28 20.35 23.67 21.02
## PAK3 0.11 0.07 0.15 0.06 0.03 0.09 0.08
## CAPN6 0.12 0.13 0.10 0.08 0.13 0.05 0.13
## DCX 0.03 0.10 0.04 0.03 0.03 0.05 0.06
## SNRPA 48.20 44.57 38.64 41.38 37.91 33.93 47.95
## SPAG6 0.10 0.19 0.11 0.22 0.09 0.11 0.20
## EXOSC5 57.04 38.89 40.27 38.43 42.00 36.56 53.45
## DYNC1I2 48.04 61.32 63.68 58.47 50.22 56.52 45.54
## APBB1IP 8.34 10.50 8.85 9.46 8.38 9.69 8.49
## LRCH4 17.86 22.22 21.24 24.74 16.97 18.85 15.21
## FAM76B 3.64 5.67 4.81 3.02 4.92 5.51 5.39
## SIRT6 42.13 37.18 40.43 45.33 52.88 46.42 46.92
## TYR 0.00 0.00 0.00 0.00 0.00 0.00 0.08
## POLD3 6.11 7.79 11.31 8.93 7.48 7.33 6.20
## ACTN2 1.23 0.65 0.43 0.79 1.42 0.92 1.50
## CAPZB 234.95 218.89 236.31 239.59 164.56 199.00 163.67
## GPR137B 6.89 9.53 6.72 6.30 8.16 8.79 9.72
## NAALAD2 0.52 0.88 0.65 0.71 0.92 1.24 0.58
## JADE1 11.08 18.14 11.48 14.29 13.33 12.89 13.40
## SLC25A43 18.07 18.10 19.60 18.51 16.15 19.04 13.47
## UBE2A 94.65 94.18 105.18 93.10 113.22 118.36 90.11
## FGFR1 77.92 115.84 87.40 110.95 93.64 114.68 90.74
## FKBP6 0.06 0.15 0.03 0.12 0.02 0.03 0.16
## GTF2I 40.14 59.58 54.97 50.48 33.93 45.88 31.30
## SMC1B 0.00 0.01 0.00 0.05 0.04 0.03 0.01
## FBLN1 0.24 0.52 0.25 0.32 0.35 0.35 0.39
## ITGA8 0.00 0.01 0.00 0.00 0.01 0.00 0.00
## CST7 0.00 0.47 0.05 0.04 0.00 0.00 0.00
## MAP2 1.50 2.49 2.97 1.40 1.72 1.59 1.53
## PIAS2 11.41 16.93 17.35 13.94 12.78 15.31 12.73
## AMPH 5.83 8.19 8.31 8.56 6.26 8.35 5.68
## ARAF 37.26 45.31 48.79 45.43 35.94 41.19 36.62
## MCCC1 9.21 9.84 10.45 10.56 13.04 9.82 9.85
## LAMP3 0.11 0.27 0.15 0.07 0.31 0.11 0.51
## FAP 17.48 19.85 17.79 17.23 20.90 19.54 18.99
## NEBL 0.20 0.22 0.17 0.05 0.10 0.12 0.11
## ACER3 3.73 5.40 5.20 4.79 4.53 5.92 3.37
## UBE2K 30.29 34.74 34.86 35.91 34.55 40.21 28.04
## PIK3C3 32.79 46.65 50.80 39.71 31.71 42.29 25.22
## N4BP2 0.83 1.88 1.53 0.92 1.56 1.62 1.55
## C12orf5 24.48 25.52 28.97 25.70 27.50 25.69 32.69
## TULP3 22.24 30.29 23.63 18.95 21.90 22.51 25.29
## SYNJ2 49.72 49.08 53.77 48.35 33.04 51.31 32.96
## ADCY2 0.08 0.06 0.03 0.01 0.00 0.02 0.12
## PPP2R5C 78.41 84.57 76.72 79.27 75.04 80.97 80.15
## RBFOX1 0.02 0.07 0.00 0.00 0.00 0.00 0.00
## GNB1 286.59 330.51 298.33 311.33 307.91 353.93 289.16
## HOXA9 0.02 0.09 0.00 0.00 0.00 0.00 0.02
## EDN1 0.17 0.24 0.35 1.03 1.13 1.30 0.41
## MLLT10 6.99 12.18 9.84 8.96 8.76 12.29 7.68
## ZCWPW1 4.15 5.38 4.33 3.71 4.66 5.17 5.28
## ADCYAP1R1 0.57 1.23 0.70 0.30 0.60 0.58 1.28
## FGF20 0.29 0.08 0.12 0.10 0.23 0.02 0.04
## P2RY10 0.10 0.11 0.05 0.02 0.02 0.13 0.15
## ITM2A 0.00 0.03 0.00 0.00 0.00 0.09 0.00
## NRD1 118.34 153.42 126.51 154.01 125.18 142.14 115.52
## VDAC3 114.17 115.08 176.40 144.94 134.04 134.03 110.66
## PCM1 33.99 48.05 36.44 43.49 42.29 40.72 38.97
## TNRC6C 0.62 1.49 1.12 0.65 1.00 0.87 1.19
## CBFA2T2 4.96 8.22 5.69 6.90 7.32 8.35 6.85
## BRINP1 0.14 0.15 0.18 0.06 0.08 0.12 0.07
## ITCH 23.93 33.69 27.87 23.07 22.76 33.02 23.79
## PKD2L2 0.29 0.31 0.35 0.33 0.17 0.21 0.35
## TP53INP2 21.46 33.24 19.84 20.98 20.98 26.18 31.86
## SDF4 201.25 211.46 166.86 203.07 210.74 195.90 197.12
## MYH7B 0.19 0.70 0.19 0.40 0.31 0.37 0.43
## BPIFB2 0.00 0.00 0.00 0.00 0.00 0.00 0.03
## TP73 0.18 0.26 0.20 0.26 0.12 0.17 0.17
## TOLLIP 58.61 54.02 49.72 57.27 76.06 73.85 74.35
## UBE2D4 13.43 13.51 13.96 13.28 11.26 13.99 12.12
## CLUL1 0.00 0.14 0.19 0.16 0.20 0.04 0.14
## RUNX1T1 0.16 0.35 0.35 0.20 0.32 0.39 0.38
## CDH17 0.01 0.06 0.03 0.08 0.03 0.01 0.19
## THOC1 19.95 26.35 24.38 25.82 26.86 24.69 24.41
## FKBP7 20.92 23.53 18.78 19.97 19.43 22.21 21.46
## OSBPL6 11.09 15.09 13.73 12.63 11.77 15.23 12.05
## SLC1A3 14.90 19.14 21.02 19.62 13.69 19.19 10.56
## XRCC5 128.29 153.30 156.70 164.86 143.53 150.22 113.49
## LXN 12.78 12.46 15.69 9.31 10.22 9.60 11.79
## SP140 0.63 1.19 0.78 1.04 0.87 0.85 1.88
## MKNK1 18.50 22.72 20.00 20.61 18.00 22.91 18.45
## TNS1 5.73 13.63 11.05 5.64 3.69 5.06 5.43
## REXO1 16.30 19.45 14.98 23.39 19.33 21.35 21.23
## SAR1A 62.62 65.71 60.35 64.65 73.83 83.58 70.80
## CDC14A 2.44 2.81 2.48 2.55 2.22 2.98 2.69
## RAPGEF3 10.29 12.46 7.90 13.57 8.47 10.52 8.59
## CEACAM1 0.29 0.39 0.31 0.21 0.32 0.37 0.20
## SENP1 8.12 13.49 12.55 9.86 10.60 14.37 11.22
## DUSP13 0.18 0.11 0.14 0.16 0.30 0.24 0.20
## CIC 28.41 44.95 41.19 48.42 32.89 42.85 23.90
## LIPE 5.53 5.50 2.88 3.66 5.05 5.35 5.63
## FDFT1 67.23 69.30 56.62 73.65 72.28 74.09 73.95
## PAFAH1B3 20.04 15.11 27.72 28.79 24.04 19.86 19.91
## OPHN1 0.82 1.49 0.99 0.93 0.98 1.02 0.91
## AFM 0.00 0.09 0.00 0.00 0.00 0.00 0.00
## KIF22 34.39 33.10 49.84 45.65 36.12 28.35 33.92
## SCGN 0.00 0.00 0.00 0.05 0.00 0.00 0.02
## LRRC16A 2.04 2.40 2.59 3.12 1.10 1.63 1.08
## PGM1 71.80 73.64 100.33 96.48 59.83 81.89 40.36
## DDX1 60.00 77.58 76.20 81.71 80.73 80.07 68.99
## DNM2 103.05 113.03 100.02 109.85 89.28 105.67 89.31
## EPB41L2 19.37 34.59 33.53 28.77 24.47 28.00 20.96
## RIMS1 0.00 0.01 0.01 0.02 0.00 0.00 0.00
## MOXD1 29.05 36.83 31.09 29.19 28.03 32.37 30.44
## STX7 16.30 17.07 18.45 15.18 15.79 17.74 17.41
## RABL2B 11.02 19.79 16.93 12.46 12.20 9.88 15.35
## KEAP1 103.21 92.99 72.94 99.94 93.80 98.24 96.45
## DDX43 0.00 0.00 0.00 0.00 0.00 0.04 0.00
## PTPRH 5.38 6.55 5.53 5.04 4.27 6.81 4.61
## DCT 0.14 0.37 0.25 0.18 0.07 0.38 0.19
## SLC35C2 74.30 88.66 68.86 58.69 56.55 53.64 72.79
## CRYBG3 11.85 19.28 19.36 20.30 17.12 18.33 12.63
## EPHA6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SCTR 0.21 0.13 0.00 0.16 0.07 0.02 0.36
## RFX3 0.80 1.15 0.79 1.04 0.68 0.86 0.66
## RIF1 3.73 6.99 7.91 5.08 6.22 7.81 5.24
## RAB21 25.28 31.43 26.55 27.85 35.84 34.45 32.98
## SLC4A4 1.89 3.29 3.13 3.29 2.13 3.10 1.76
## SMARCA2 20.00 32.36 28.33 22.26 21.23 21.34 25.27
## RDH8 4.04 4.84 2.77 2.33 1.13 1.96 2.65
## SESN1 5.27 8.89 7.92 5.93 8.43 7.01 8.99
## MID2 0.02 0.04 0.05 0.01 0.05 0.03 0.07
## PIH1D3 0.00 0.03 0.00 0.00 0.00 0.00 0.00
## COL5A3 47.27 64.20 35.00 32.98 22.14 27.02 36.96
## SRCAP 14.32 22.01 17.50 19.29 17.04 27.00 17.34
## KIAA0020 33.25 33.72 34.69 42.57 55.56 46.42 46.03
## CPB2 0.00 0.03 0.03 0.07 0.08 0.04 0.13
## CHRNA3 0.41 0.41 0.67 0.48 0.88 0.90 0.80
## KCNN2 0.26 0.35 0.27 0.12 0.21 0.34 0.14
## CNOT4 12.13 15.33 13.20 12.71 15.53 18.84 14.11
## PSEN1 37.72 41.08 37.29 38.00 38.03 45.65 36.82
## CPOX 19.57 27.55 34.14 34.01 26.23 28.72 15.30
## CLDND1 165.66 187.76 172.70 147.07 166.92 192.99 190.44
## MOK 245.60 143.08 153.87 242.73 124.11 162.06 157.07
## HSP90AA1 892.76 1157.72 1075.25 1242.65 1230.53 1378.42 834.87
## RBL1 5.13 7.41 14.67 12.28 9.72 9.87 5.08
## DLGAP4 67.06 86.23 53.34 62.67 52.09 73.70 58.30
## IGSF9B 0.41 0.89 1.72 0.94 0.47 0.97 0.38
## CFHR2 0.08 0.16 0.12 0.00 0.00 0.15 0.18
## NDC80 11.82 13.50 22.52 17.27 9.62 9.91 8.98
## AP4E1 4.54 8.54 7.62 6.11 6.47 7.41 5.94
## RSBN1 6.35 9.71 7.67 7.48 6.47 7.59 5.54
## MAGI3 3.37 3.86 3.44 3.17 2.49 3.01 3.05
## CXCL2 632.48 630.31 384.66 349.06 702.19 481.27 855.12
## AFP 4.90 4.08 5.93 6.39 8.52 6.31 5.27
## COL4A4 0.06 0.08 0.05 0.03 0.05 0.05 0.08
## TCF7 26.66 36.75 30.79 23.95 19.64 24.39 16.94
## OSTM1 55.20 71.91 66.95 65.36 78.62 86.18 72.81
## CDH7 0.47 0.79 1.06 0.31 0.72 0.64 0.51
## IMPG2 0.04 0.07 0.04 0.02 0.02 0.04 0.01
## PCNP 96.71 117.17 118.24 107.57 114.52 123.70 95.84
## EXD2 0.04 0.13 0.04 0.03 0.04 0.03 0.03
## ARG2 8.93 8.43 9.54 7.46 6.31 7.73 8.51
## MEF2C 2.59 3.88 2.05 1.09 1.38 1.34 3.32
## PTPRC 0.01 0.00 0.01 0.01 0.02 0.02 0.01
## CACNA1S 0.00 0.01 0.00 0.00 0.00 0.01 0.01
## PKP1 2.00 2.71 2.23 1.56 1.02 1.03 1.56
## UBA5 24.85 40.01 44.30 33.35 38.26 33.78 26.17
## STK17B 6.71 8.42 7.23 7.26 10.39 10.72 9.90
## CDC14B 4.10 5.70 3.53 3.83 3.07 5.20 5.25
## ZNF510 2.96 4.20 3.62 3.37 2.62 3.63 2.38
## LRP2 0.03 0.06 0.02 0.01 0.08 0.01 0.05
## ZNF506 0.21 0.22 0.09 0.10 0.16 0.13 0.21
## JMJD4 10.67 9.72 11.55 9.73 9.81 8.20 12.27
## DUSP12 31.75 27.77 32.72 29.27 33.57 27.50 30.24
## AACS 11.94 12.47 10.93 15.40 13.11 13.84 11.23
## KIAA0141 47.08 49.03 55.14 44.82 37.76 42.23 38.48
## SLC13A1 0.01 0.04 0.07 0.01 0.03 0.02 0.07
## CADPS2 6.63 9.79 6.48 5.50 2.97 4.43 3.27
## PCDHB4 0.13 0.30 0.31 0.12 0.13 0.12 0.17
## PCDHA6 0.00 0.04 0.02 0.02 0.09 0.00 0.01
## PCDHGA2 0.86 1.23 0.84 0.91 0.84 0.85 0.83
## HSPB11 123.60 102.70 146.37 122.25 116.60 105.68 105.83
## PHLPP1 2.18 3.09 2.69 3.73 2.90 3.91 2.15
## ATP8B1 0.17 0.32 0.13 0.20 0.14 0.29 0.07
## IL12RB2 0.07 0.10 0.08 0.10 0.07 0.12 0.16
## SMARCD3 42.54 57.70 46.56 48.44 40.55 38.13 41.95
## WDR70 22.01 21.33 20.10 24.69 18.03 18.16 12.42
## FYB 0.29 0.20 0.10 0.05 0.08 0.07 0.13
## MPP4 16.60 18.30 15.04 16.46 10.25 12.50 12.09
## STRADB 29.11 35.75 31.95 30.37 32.01 29.44 33.97
## BZW1 213.32 265.11 268.87 248.71 313.94 334.37 285.78
## PGR 0.02 0.07 0.05 0.07 0.07 0.14 0.06
## C1QTNF3 0.56 0.92 0.46 0.13 0.20 0.38 0.21
## ME2 27.17 33.63 34.73 29.95 35.52 30.36 32.98
## C5orf22 12.20 16.42 11.55 10.89 15.56 15.61 18.45
## CCNT2 5.45 8.19 9.04 7.28 7.74 9.15 8.37
## FAM135A 1.48 2.42 1.89 1.92 2.06 2.47 2.46
## COL19A1 0.26 0.34 0.14 0.11 0.14 0.06 0.24
## EPB41L3 0.21 0.28 0.20 0.09 0.28 0.15 0.29
## COBLL1 2.12 3.79 5.49 2.99 3.63 4.24 2.68
## DLG3 4.28 5.20 5.28 4.45 3.18 4.58 4.27
## KCNK2 0.20 0.26 0.08 0.16 0.06 0.09 0.31
## SERTAD4 0.01 0.00 0.01 0.13 0.09 0.00 0.00
## TRAF5 1.59 2.33 1.84 1.49 2.00 1.50 2.06
## MRPL22 94.82 69.61 79.59 79.57 65.11 73.27 68.94
## GEMIN5 6.45 7.83 6.24 6.43 7.76 8.32 7.39
## OPRK1 0.34 0.58 0.14 0.22 0.28 0.36 0.53
## NFE2L1 239.43 353.83 216.28 196.82 264.76 256.41 357.44
## SEMA5B 0.09 0.35 0.16 0.11 0.05 0.07 0.20
## GSK3B 13.76 16.93 16.90 15.40 15.78 18.24 12.59
## ITGB5 52.98 65.31 61.02 67.22 47.80 54.37 45.77
## ERC1 6.23 10.42 8.52 9.21 6.65 10.58 6.45
## XPO1 37.41 58.56 52.73 48.81 58.94 58.09 63.39
## C4orf6 1.47 0.81 2.16 0.71 0.74 0.82 0.49
## RNF13 28.94 25.75 31.99 23.27 23.18 28.50 24.33
## TRPM3 0.28 0.37 0.31 0.14 0.49 0.51 1.20
## PALB2 9.04 10.62 14.01 14.22 14.93 12.96 11.40
## DOPEY1 1.12 1.73 1.75 1.23 1.12 1.44 1.25
## LYRM2 38.22 46.13 49.20 32.39 47.56 36.54 54.69
## BCKDHB 4.63 5.61 5.16 4.39 3.68 3.82 4.09
## mRNA_R59 mRNA_R63 mRNA_R62 mRNA_R61 mRNA_R60 mRNA_R58 mRNA_R57
## TSPAN6 16.09 15.69 16.39 11.46 9.38 14.81 9.84
## TNMD 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DPM1 101.79 105.81 110.63 91.56 85.66 100.57 70.69
## SCYL3 4.33 5.21 5.92 3.56 3.49 4.09 4.40
## C1orf112 16.98 16.10 11.90 17.67 13.37 19.29 12.16
## FGR 0.03 0.05 0.09 0.04 0.03 0.00 0.03
## CFH 1.90 2.12 2.38 1.40 1.58 2.13 1.44
## FUCA2 93.27 90.46 85.90 86.65 73.60 101.87 73.84
## GCLC 32.14 36.21 46.19 36.90 90.60 55.33 152.47
## NFYA 33.10 34.14 34.48 23.96 25.79 27.54 39.42
## STPG1 15.57 14.36 12.88 20.47 15.35 20.02 21.73
## NIPAL3 23.09 27.72 23.15 23.97 18.02 25.96 28.29
## LAS1L 48.16 47.81 35.15 50.86 41.48 52.53 53.07
## ENPP4 5.44 7.20 5.96 4.06 4.53 5.42 5.63
## SEMA3F 4.29 4.71 4.12 2.82 1.96 3.10 2.65
## CFTR 0.00 0.01 0.01 0.00 0.00 0.00 0.01
## ANKIB1 16.47 19.68 18.46 12.99 14.26 17.95 18.69
## CYP51A1 48.74 41.34 41.66 56.85 70.16 66.99 105.70
## KRIT1 19.33 17.89 19.29 13.48 14.76 17.13 17.40
## RAD52 4.82 4.06 4.86 2.85 2.02 3.10 4.71
## BAD 134.39 135.72 147.59 147.69 108.22 149.82 89.92
## LAP3 62.82 61.30 54.13 58.59 63.65 67.34 68.50
## CD99 355.92 326.15 354.38 339.80 305.79 367.54 283.13
## HS3ST1 5.16 3.09 5.02 3.73 1.68 3.25 2.00
## AOC1 0.00 0.00 0.00 0.00 0.00 0.02 0.02
## WNT16 0.02 0.02 0.06 0.03 0.06 0.00 0.06
## HECW1 1.15 1.74 1.02 1.16 1.86 1.01 1.67
## MAD1L1 53.39 51.39 55.14 57.78 86.94 56.20 126.65
## LASP1 232.37 224.97 201.77 213.83 205.27 243.80 227.04
## SNX11 16.31 17.16 16.58 17.94 23.71 19.39 27.45
## TMEM176A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## M6PR 81.98 73.43 64.31 98.76 98.40 106.45 162.00
## KLHL13 0.03 0.00 0.13 0.02 0.03 0.02 0.03
## CYP26B1 2.28 2.65 2.61 1.30 0.95 2.07 1.58
## ICA1 2.87 5.34 4.94 2.31 3.39 2.88 4.26
## DBNDD1 1.49 1.65 1.59 0.70 0.41 1.11 0.37
## ALS2 18.65 18.07 16.01 14.87 16.38 15.33 21.19
## CASP10 2.27 2.55 2.49 1.43 1.41 1.45 1.84
## CFLAR 82.21 69.67 80.74 45.83 46.27 52.58 49.27
## TFPI 121.79 139.77 141.38 103.15 78.53 116.88 77.03
## NDUFAF7 10.17 11.93 12.43 9.91 7.52 10.46 10.48
## RBM5 62.26 61.60 59.63 45.99 48.24 44.23 72.54
## MTMR7 0.72 0.89 0.91 0.64 0.78 0.85 0.99
## SLC7A2 8.43 11.17 9.05 5.47 4.82 7.25 4.42
## ARF5 146.07 144.28 155.03 149.77 151.26 144.19 155.43
## SARM1 0.92 0.94 0.97 0.55 0.84 1.18 0.75
## POLDIP2 106.95 102.38 96.62 116.95 104.03 110.52 109.09
## PLXND1 55.40 51.10 60.31 41.42 30.84 50.23 33.25
## AK2 184.73 165.29 145.38 187.18 147.53 196.74 156.25
## CD38 0.23 0.19 0.16 0.04 0.06 0.12 0.10
## FKBP4 96.02 81.11 72.25 93.24 81.48 100.52 84.89
## KDM1A 61.24 58.87 56.58 51.73 41.44 57.89 48.56
## RBM6 41.00 40.09 38.42 36.41 35.42 40.50 46.20
## CAMKK1 4.41 5.69 5.02 4.37 3.80 5.35 5.15
## RECQL 34.04 37.09 29.52 28.08 32.65 35.72 36.92
## CCDC132 10.82 12.07 12.94 9.62 10.25 11.31 13.26
## HSPB6 0.06 0.05 0.15 0.03 0.06 0.00 0.10
## ARHGAP33 7.03 6.22 4.39 8.18 6.12 7.71 8.45
## NDUFAB1 126.20 124.31 125.63 130.66 126.53 135.35 126.92
## PDK4 0.65 1.64 3.00 0.37 0.52 0.57 0.41
## SLC22A16 0.00 0.06 0.00 0.00 0.00 0.00 0.00
## ZMYND10 0.49 0.65 0.37 0.40 0.16 0.47 0.95
## ABCB5 0.00 0.00 0.01 0.00 0.00 0.00 0.05
## ARX 0.02 0.03 0.01 0.01 0.03 0.00 0.03
## SLC25A13 20.46 18.86 20.93 22.04 20.83 22.72 25.42
## ST7 23.25 21.61 21.36 24.23 20.80 27.12 25.04
## CDC27 75.64 76.88 72.21 52.51 49.64 71.89 63.37
## SLC4A1 0.00 0.00 0.01 0.03 0.01 0.02 0.02
## CALCR 2.74 2.39 3.57 1.61 1.20 2.70 1.15
## HCCS 69.53 64.28 63.14 62.86 66.53 70.01 65.01
## DVL2 36.58 35.05 33.89 36.93 34.22 40.06 52.10
## PRSS22 6.14 6.91 8.46 4.52 6.77 3.76 10.20
## UPF1 45.67 40.24 37.18 38.85 36.38 41.50 45.90
## SKAP2 29.19 33.01 37.56 19.66 22.83 27.01 31.71
## SLC25A5 513.65 493.45 443.25 552.18 441.16 545.64 369.25
## CCDC109B 43.02 42.05 43.23 39.82 33.74 44.19 31.66
## HOXA11 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## POLR2J 164.58 137.30 140.73 177.75 148.67 163.07 153.05
## DHX33 15.67 14.50 11.77 13.23 13.64 13.39 20.08
## MEOX1 0.00 0.00 0.01 0.00 0.02 0.00 0.00
## THSD7A 0.01 0.00 0.05 0.09 0.07 0.01 0.13
## LIG3 8.96 10.21 7.92 7.38 7.11 8.55 9.20
## RPAP3 24.57 25.84 24.54 23.98 21.82 27.70 24.60
## ACSM3 0.40 0.59 0.55 0.34 0.39 0.59 0.55
## AC004381.6 3.72 3.80 2.72 3.24 3.84 4.33 4.39
## CIAPIN1 44.59 42.00 38.38 46.90 46.56 45.60 49.47
## FAM214B 14.61 19.99 21.35 13.16 17.67 16.70 21.94
## COPZ2 8.76 8.09 10.09 7.97 7.64 6.73 7.51
## PRKAR2B 1.71 1.93 1.42 1.35 1.13 1.93 1.85
## MSL3 20.86 25.01 22.65 21.28 19.63 21.50 20.11
## CREBBP 8.71 9.93 8.32 5.94 8.60 7.47 11.06
## BZRAP1 7.93 8.29 10.38 4.58 3.57 4.42 3.90
## MPO 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PON1 0.00 0.06 0.05 0.01 0.09 0.27 0.07
## GCFC2 21.56 19.44 17.77 21.20 17.49 20.03 18.75
## WDR54 35.02 35.90 34.97 38.03 27.45 39.55 29.14
## CROT 5.40 6.09 5.48 5.44 5.39 5.77 5.36
## ABCB4 0.00 0.13 0.00 0.00 0.01 0.00 0.00
## KMT2E 18.03 18.54 16.75 11.69 13.66 14.33 21.57
## RHBDD2 44.68 44.86 46.78 41.06 38.06 39.80 44.22
## SOX8 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## IBTK 24.12 26.65 27.28 17.41 21.54 21.38 25.55
## ZNF195 18.68 16.77 15.70 16.63 20.13 18.15 27.59
## MYCBP2 9.02 10.82 10.71 7.45 8.40 9.21 9.84
## FBXL3 21.25 22.60 22.35 17.22 17.54 21.43 21.57
## ITGAL 0.14 0.10 0.04 0.00 0.00 0.01 0.02
## PDK2 23.83 27.67 28.65 17.08 18.48 25.46 30.88
## ITGA3 597.03 511.59 435.32 605.71 395.90 616.84 513.82
## ZFX 12.14 12.59 12.13 8.14 9.28 9.80 12.92
## LAMP2 172.80 169.53 162.74 137.82 146.48 179.49 180.42
## GGNBP2 69.72 65.87 64.71 59.70 59.76 65.49 77.29
## ITGA2B 0.29 0.24 0.18 0.03 0.09 0.01 0.32
## ASB4 0.06 0.13 0.41 0.01 0.16 0.07 0.00
## GDE1 47.79 45.33 48.83 39.76 40.01 51.28 43.31
## C19orf60 40.73 40.56 46.87 42.40 45.68 44.71 43.55
## CRLF1 2.65 2.23 1.52 2.03 1.99 1.81 2.07
## OSBPL7 4.90 5.82 6.14 4.19 3.03 3.83 4.84
## TMEM98 0.42 0.27 0.23 0.35 0.21 0.45 0.23
## YBX2 0.02 0.00 0.04 0.01 0.00 0.02 0.06
## KRT33A 0.00 0.00 0.00 0.00 0.00 0.03 0.00
## ABCC8 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## CCL18 0.00 0.00 0.00 0.00 0.00 0.00 0.29
## CCL3 0.05 0.06 0.00 0.00 0.00 0.06 0.26
## SYNRG 8.01 10.17 8.43 5.97 7.27 7.28 11.34
## CACNG3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMEM132A 45.70 39.41 41.13 37.74 22.59 35.66 29.81
## AP2B1 145.49 162.09 135.73 124.38 119.90 150.22 153.39
## TAC1 0.00 0.00 0.03 0.00 0.00 0.00 0.00
## ZNF263 19.86 17.17 18.79 19.60 20.22 17.06 24.52
## CX3CL1 5.18 5.22 6.82 1.64 1.57 2.06 1.84
## SPATA20 37.76 42.02 44.23 32.09 37.36 30.18 52.12
## CACNA1G 0.03 0.05 0.03 0.04 0.06 0.03 0.07
## TNFRSF12A 376.67 325.83 324.91 445.57 406.41 400.61 417.01
## DLX6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MAP3K9 3.48 4.24 3.26 3.22 3.24 3.28 5.35
## RALA 50.55 45.57 47.98 50.07 55.69 54.14 69.27
## BAIAP2L1 30.44 26.05 27.15 26.52 29.92 28.67 36.32
## KDM7A 1.27 1.90 2.11 1.01 1.97 1.31 3.15
## ETV1 38.35 50.03 48.61 17.65 20.32 31.69 23.89
## AGK 27.02 22.82 23.63 22.66 20.44 26.76 22.84
## ALDH3B1 24.10 34.04 35.83 16.70 14.07 19.26 17.77
## TTC22 0.43 0.33 0.38 0.18 0.34 0.22 0.29
## PHTF2 21.20 20.38 15.18 21.09 22.44 23.79 26.77
## CCL26 6.51 5.24 6.60 4.41 4.04 4.70 2.70
## FARP2 12.32 8.81 8.87 8.51 10.09 9.79 16.08
## USH1C 0.00 0.00 0.00 0.01 0.00 0.00 0.00
## GGCT 81.44 61.08 48.38 97.05 80.12 95.82 68.97
## DBF4 34.62 30.97 23.84 32.65 30.80 37.62 32.06
## TBXA2R 1.22 1.28 1.08 1.08 0.94 1.46 0.97
## IFRD1 45.22 41.24 41.86 45.46 67.09 48.96 78.91
## LGALS14 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## COX10 14.27 13.50 11.15 13.38 15.17 14.31 20.78
## GTF2IRD1 21.70 22.33 29.35 25.02 22.35 24.04 25.11
## PAF1 60.35 60.39 57.12 49.29 37.07 56.93 38.21
## VPS41 20.73 23.71 23.16 15.54 21.40 20.51 33.98
## ARHGAP44 0.08 0.08 0.08 0.08 0.06 0.09 0.07
## ELAC2 60.82 60.05 49.31 59.30 42.21 62.02 46.84
## SCIN 0.45 0.50 0.76 0.23 0.14 0.31 0.30
## ARSD 5.92 7.15 7.22 5.37 6.95 5.71 8.79
## PNPLA4 25.47 21.83 22.85 19.55 26.38 23.39 29.13
## MYH13 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ADIPOR2 31.35 32.22 31.82 30.32 33.11 33.07 41.62
## CDKL3 3.13 3.41 3.75 2.81 4.73 3.83 5.50
## UPP2 0.00 0.01 0.00 0.00 0.00 0.00 0.00
## PRSS21 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MARK4 10.60 12.69 13.06 7.82 7.12 9.18 11.25
## PROM1 0.00 0.12 0.06 0.02 0.15 0.09 0.19
## CCDC124 170.11 149.95 148.67 194.44 150.86 193.36 142.11
## CEACAM21 0.00 0.00 0.00 0.00 0.00 0.02 0.00
## PAFAH1B1 100.87 98.23 97.39 75.72 98.04 93.50 111.14
## NOS2 0.00 0.02 0.02 0.01 0.02 0.00 0.03
## DNAH9 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## KIAA0100 57.00 57.63 48.34 49.86 42.74 62.50 45.90
## SLC13A2 0.01 0.01 0.01 0.00 0.00 0.00 0.04
## GAS7 0.40 0.35 0.76 0.36 0.13 0.65 0.38
## TRAPPC6A 6.91 6.84 9.37 5.45 6.70 6.79 8.11
## MATK 0.10 0.17 0.10 0.10 0.38 0.39 0.68
## CEACAM7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CD79B 0.05 0.00 0.00 0.04 0.00 0.00 0.00
## SCN4A 0.00 0.00 0.01 0.00 0.00 0.09 0.01
## ST7L 28.79 24.33 25.99 28.34 23.33 31.45 24.82
## TKTL1 0.00 0.06 0.01 0.00 0.00 0.00 0.00
## PAX6 0.48 0.56 0.53 0.36 0.50 0.50 0.40
## RPUSD1 22.75 19.17 20.28 28.70 19.92 25.49 20.16
## RHBDF1 27.64 29.61 31.85 27.22 21.98 21.43 30.06
## LUC7L 36.87 34.36 38.39 31.03 25.32 33.62 19.74
## CACNA2D2 0.11 0.21 0.17 0.12 0.06 0.16 0.08
## BAIAP3 5.26 5.60 7.03 3.24 3.76 3.38 5.93
## TSR3 46.86 46.63 50.60 56.52 44.26 54.20 42.72
## PIGQ 20.42 20.09 20.16 16.92 12.61 17.41 13.99
## CRAMP1L 5.73 6.50 6.68 4.19 5.00 5.62 8.29
## TEAD3 35.77 34.51 34.91 34.98 35.00 32.88 46.14
## SELE 0.00 0.01 0.01 0.00 0.00 0.00 0.00
## DNAJC11 42.51 42.84 33.43 40.41 35.19 42.00 47.18
## FMO3 0.72 0.89 0.75 0.37 0.18 0.68 0.14
## MYLIP 17.21 20.59 19.85 11.97 13.02 15.54 15.61
## NOX1 0.25 0.19 0.06 0.11 0.03 0.08 0.06
## E2F2 5.13 3.53 2.12 3.36 1.20 3.85 0.82
## PSMB1 419.31 426.93 434.35 440.73 471.20 465.74 400.21
## SYN1 0.30 0.34 0.47 0.08 0.13 0.21 0.17
## JARID2 25.00 35.58 30.15 23.27 26.51 22.99 35.94
## CDKL5 0.38 0.63 0.50 0.10 0.24 0.43 0.60
## CAMK1G 0.01 0.03 0.08 0.05 0.01 0.09 0.17
## CDK11A 40.99 39.40 39.40 40.61 40.61 35.85 52.20
## NADK 57.76 64.44 73.88 53.87 55.64 57.62 63.94
## TFAP2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TFAP2D 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## DLEC1 0.09 0.17 0.16 0.07 0.29 0.06 0.09
## CYTH3 20.76 19.74 19.36 22.27 20.83 23.27 23.87
## ADAM22 0.90 0.93 0.79 0.65 0.44 0.63 0.21
## SYPL1 120.37 124.03 120.85 119.21 127.52 134.30 143.52
## CYB561 45.61 46.63 54.44 33.33 30.55 41.37 37.19
## SPAG9 37.81 43.69 40.28 36.03 48.86 36.62 66.87
## CELSR3 1.65 2.39 2.46 1.50 1.10 1.14 1.97
## AASS 13.20 13.60 11.87 9.38 8.88 10.82 11.42
## PLEKHG6 0.34 0.22 0.32 0.20 0.34 0.04 0.18
## SS18L2 36.29 31.37 32.99 38.99 33.67 39.60 36.20
## MPND 9.98 10.22 9.72 9.02 7.31 7.50 4.99
## MGST1 339.46 321.98 357.11 407.40 484.78 447.26 539.93
## CRY1 19.68 18.14 18.40 15.78 15.72 16.49 15.10
## PGLYRP1 0.00 0.03 0.10 0.00 0.22 0.00 0.05
## NFIX 31.32 30.45 25.31 22.07 22.35 26.28 29.65
## ST3GAL1 14.04 16.17 15.48 12.37 10.13 16.06 12.66
## MMP25 0.41 0.27 0.18 0.14 0.34 0.11 0.35
## IL32 92.08 79.28 90.35 86.17 65.90 69.64 71.39
## PKD1 17.05 20.73 18.70 20.30 23.38 19.42 35.71
## MAPK8IP2 0.16 0.21 0.23 0.11 0.21 0.14 0.31
## MED24 57.97 63.69 63.85 48.15 41.53 54.99 46.69
## RHOBTB2 5.04 5.17 4.15 5.13 5.13 5.38 8.09
## HEATR5B 4.53 5.72 5.50 4.09 4.99 4.38 6.33
## SEC62 97.14 93.91 91.96 73.93 69.10 93.78 84.03
## RPS20 1298.83 1253.67 1319.47 1344.94 1452.11 1369.19 1134.87
## CSDE1 259.51 263.85 251.58 205.00 212.37 250.30 245.90
## UBE3C 58.31 56.34 49.76 49.71 52.96 58.86 61.98
## REV3L 6.03 7.00 7.63 4.60 7.26 5.83 6.83
## TENM1 0.00 0.01 0.14 0.01 0.01 0.01 0.01
## PAX7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MASP2 0.60 0.79 0.57 0.43 0.70 0.41 0.85
## IYD 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## FAM76A 6.14 5.81 5.06 4.82 4.93 5.92 6.72
## TRAF3IP3 1.30 1.56 1.65 1.26 0.99 1.99 1.48
## POMT2 21.27 19.59 21.22 20.46 16.94 18.98 20.62
## VTA1 35.12 30.26 28.68 30.54 31.18 38.46 36.68
## MLXIPL 3.51 4.84 7.39 1.66 1.10 1.84 2.31
## BAZ1B 38.34 37.71 33.79 30.07 34.39 37.39 43.11
## RANBP9 65.38 65.65 62.14 57.93 62.75 68.08 82.01
## ETV7 5.58 5.68 7.23 1.67 1.40 1.81 1.18
## SPRTN 9.46 8.79 8.99 8.08 6.75 9.70 7.08
## METTL13 21.61 23.21 21.07 22.20 24.85 24.19 32.24
## DYRK4 26.97 29.02 23.62 25.84 19.22 25.81 22.68
## ZNF207 108.47 89.79 87.41 78.26 62.04 80.61 70.31
## UQCRC1 128.19 121.20 137.45 108.73 90.86 134.29 85.04
## STARD3NL 49.66 53.25 50.07 50.34 49.26 54.98 51.90
## CD9 315.73 357.64 377.48 278.12 292.86 332.35 298.29
## HHATL 0.00 0.13 0.00 0.04 0.02 0.09 0.10
## NCAPD2 56.89 62.57 45.73 51.68 34.00 57.61 39.49
## IFFO1 1.73 1.78 1.75 1.55 1.27 1.18 1.53
## GIPR 1.35 1.71 2.20 1.07 0.67 1.03 1.48
## PHF7 12.80 16.38 14.32 14.85 12.01 15.62 15.26
## SEMA3G 0.11 0.07 0.09 0.04 0.08 0.12 0.04
## NISCH 20.91 23.46 23.36 18.86 22.74 17.99 38.99
## STAB1 0.00 0.12 0.03 0.03 0.02 0.00 0.02
## FUZ 4.82 4.20 5.33 3.12 2.31 3.95 3.41
## SLC6A13 0.23 0.10 0.46 0.04 0.12 0.23 0.32
## IDS 86.28 99.22 87.74 71.38 84.03 82.20 111.85
## PRSS3 25.73 30.08 28.74 30.76 15.17 29.47 13.72
## ZNF200 5.60 5.78 4.60 5.26 5.32 4.66 6.68
## CD4 0.00 0.00 0.00 0.00 0.01 0.02 0.07
## LRRC23 8.71 7.75 9.36 7.58 6.06 7.99 7.96
## BTK 0.23 0.27 0.11 0.02 0.01 0.02 0.11
## HFE 18.64 19.39 18.50 9.71 6.83 13.90 7.31
## SCMH1 28.13 24.23 22.32 22.71 14.79 21.89 15.90
## FYN 29.19 29.09 26.82 32.35 24.63 29.95 38.28
## HIVEP2 9.18 11.57 10.89 5.93 8.30 7.24 10.86
## FMO1 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## TCEB3 31.43 29.58 25.68 28.37 34.33 31.55 43.24
## LYPLA2 80.67 79.95 86.54 81.44 81.54 81.09 92.35
## CLCN6 5.47 5.63 6.15 7.08 6.26 6.18 11.93
## MRC2 11.17 9.96 11.63 6.83 4.72 8.16 6.50
## NME2 574.98 605.00 482.31 700.16 586.40 558.78 820.70
## SLC6A7 0.09 0.10 0.10 0.02 0.01 0.01 0.06
## TSPAN9 26.19 22.77 21.83 17.37 14.68 24.03 10.51
## BTBD7 11.69 12.89 12.21 11.56 12.09 12.33 15.24
## APBA3 16.44 16.78 19.07 15.71 9.42 15.66 11.95
## MKS1 10.67 13.47 11.63 9.07 7.29 9.03 10.76
## ABHD5 37.94 30.79 26.35 54.94 56.71 51.09 80.05
## KAL1 22.71 20.83 20.46 15.87 9.28 20.33 9.90
## AKAP8L 63.78 62.87 68.32 55.40 53.90 53.27 59.45
## MBTD1 3.52 4.84 4.82 3.33 4.98 3.62 5.79
## UTP18 75.74 68.99 63.95 75.49 78.03 85.88 81.51
## RNF216 19.60 20.89 20.35 18.24 15.53 16.67 19.40
## TTC19 46.07 46.78 44.84 39.32 42.42 45.58 58.78
## PTBP1 242.52 194.97 145.12 244.70 206.71 235.34 241.35
## DPF1 3.72 3.49 2.61 4.90 3.12 4.31 3.96
## SYT7 0.17 0.11 0.20 0.21 0.32 0.24 1.24
## LARS2 16.97 15.99 13.26 13.59 14.07 16.00 15.99
## PIK3C2A 11.47 12.05 11.16 7.66 14.44 11.17 20.57
## PLAUR 122.31 115.90 104.31 138.68 127.35 127.31 159.66
## ANLN 132.05 150.26 99.03 131.21 89.74 138.89 101.55
## WIZ 25.26 23.82 20.89 20.49 17.60 22.66 25.50
## RABGAP1 17.04 20.53 19.50 13.83 14.42 17.13 18.72
## DCN 0.00 0.01 0.03 0.03 0.00 0.15 0.00
## QPCTL 16.50 16.63 19.35 18.57 13.50 18.16 13.60
## PPP5C 82.01 75.14 60.37 81.39 58.34 87.46 65.23
## CEP68 4.30 5.20 4.30 3.86 3.72 4.21 5.81
## MAP4K3 15.21 17.27 17.49 12.44 12.42 14.04 16.10
## ZBTB32 0.02 0.02 0.08 0.03 0.06 0.05 0.07
## TYROBP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMEM159 21.94 22.04 23.60 30.20 34.31 31.25 52.32
## GABRA3 0.02 0.03 0.01 0.01 0.00 0.01 0.02
## BRCA1 12.70 12.64 8.48 12.47 9.70 16.37 11.50
## ERCC1 66.67 60.68 58.89 72.62 52.57 60.56 55.32
## CD22 15.23 17.02 13.02 18.50 17.18 18.45 23.51
## MBTPS2 17.81 20.26 18.38 12.61 15.52 16.99 18.41
## PRICKLE3 10.22 9.82 10.93 9.39 10.57 8.92 13.67
## LTF 0.39 0.38 0.28 0.12 0.42 0.23 0.50
## EXTL3 13.13 14.43 11.52 11.21 9.52 13.44 12.43
## NR1H4 0.00 0.00 0.01 0.00 0.00 0.01 0.04
## ELOVL5 187.39 169.96 157.17 180.79 179.06 203.32 184.62
## ALOX5 2.76 3.16 4.03 1.45 1.22 1.97 1.47
## KDM5D 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CALCOCO1 32.79 35.14 46.73 18.08 16.34 22.59 27.45
## UBR7 40.93 39.09 28.79 39.95 30.33 44.65 29.90
## MAP4K5 30.81 29.12 29.76 26.62 27.69 27.39 36.42
## EHD3 1.91 1.67 1.95 0.76 0.50 1.32 0.59
## PSMC4 113.50 99.69 91.62 118.39 106.06 115.00 112.84
## MAN2B2 22.45 23.54 22.74 18.11 14.63 20.99 17.17
## SLC7A14 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CLDN11 0.40 0.32 0.22 0.30 0.12 0.15 0.35
## SLC25A39 165.76 155.20 152.93 185.36 142.08 170.39 167.69
## MVP 116.17 123.73 124.51 94.23 76.64 107.38 99.85
## NUB1 100.31 105.70 102.86 69.65 67.26 88.16 83.83
## PGM3 35.20 35.07 35.15 31.72 34.36 36.25 42.81
## RWDD2A 7.26 7.93 8.56 7.56 8.99 7.99 10.12
## CLK1 36.06 38.88 50.60 36.45 49.40 32.06 48.03
## POLR3B 4.86 5.28 5.13 4.66 3.90 5.51 4.36
## ANGEL1 5.27 5.44 5.23 4.43 4.38 4.97 6.03
## RNF14 46.45 47.61 45.92 43.54 64.92 53.04 83.66
## DNASE1L1 25.39 25.92 28.44 26.00 15.15 26.25 19.37
## DDX11 27.67 23.13 18.04 29.29 19.98 23.01 26.48
## HEBP1 80.78 70.15 73.23 88.76 92.66 88.93 100.57
## GPRC5A 60.28 65.74 58.66 52.45 33.86 45.99 47.34
## MAMLD1 17.10 17.93 15.52 11.96 7.60 15.86 9.00
## CD6 0.00 0.01 0.01 0.02 0.00 0.00 0.04
## TACC3 97.38 91.15 68.31 101.62 51.98 97.06 59.94
## UFL1 9.28 10.49 10.93 5.87 7.34 8.09 8.86
## POLA2 24.69 20.49 15.80 22.21 9.95 22.40 10.41
## ZC3H3 9.70 9.86 8.36 9.88 9.02 9.98 14.17
## CAPN1 125.56 127.76 127.00 101.31 78.33 116.71 80.07
## ACPP 0.06 0.04 0.14 0.17 0.02 0.09 0.06
## MDH1 166.42 171.99 171.37 145.98 132.63 171.92 145.93
## SLC30A9 36.46 37.63 39.14 28.41 28.65 34.26 31.51
## MTMR11 15.63 18.69 18.47 12.92 12.55 13.51 15.88
## COX15 17.07 15.76 14.82 12.83 13.79 15.30 18.11
## CCDC88C 7.50 8.37 6.83 6.89 5.24 7.22 5.25
## YAF2 9.88 7.13 9.10 6.87 10.04 10.97 13.60
## ZMYND11 40.02 39.12 37.11 30.81 32.23 39.51 38.40
## WAS 0.68 1.20 0.85 0.55 0.91 0.68 0.79
## DPEP1 0.18 0.34 0.27 0.22 0.08 0.21 0.15
## BID 47.75 40.39 53.21 43.71 34.01 49.84 25.05
## MATR3 268.00 242.96 202.57 216.72 229.63 250.39 257.33
## NPC1L1 0.03 0.03 0.07 0.03 0.03 0.02 0.07
## XYLT2 11.23 13.63 10.94 9.44 5.96 10.53 8.27
## RGPD5 3.19 4.05 3.81 1.25 2.99 2.03 7.26
## STMN4 0.00 0.00 0.02 0.08 0.00 0.00 0.00
## NUDCD3 39.72 33.62 32.83 33.62 26.25 33.53 39.30
## ISL1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CHDH 0.15 0.20 0.10 0.12 0.05 0.20 0.05
## IL20RA 0.88 0.71 0.84 0.23 0.32 0.51 0.43
## CLCA1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CLCA4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## GLT8D1 90.37 87.96 90.99 72.82 58.12 81.41 66.37
## ATP2C1 64.18 63.91 63.86 56.78 51.97 67.68 55.22
## SRCIN1 0.28 0.19 0.25 0.13 0.09 0.21 0.30
## IGF1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SLC38A5 1.84 1.58 1.39 1.65 1.45 1.16 0.68
## MAGIX 1.91 2.01 3.07 1.35 1.42 1.51 1.24
## RALBP1 45.17 47.38 42.93 40.67 40.50 46.72 52.99
## RUFY3 13.97 16.32 16.42 12.92 11.68 12.33 17.19
## CNTN1 0.05 0.04 0.01 0.01 0.00 0.00 0.01
## SLC11A1 0.13 0.06 0.15 0.07 0.06 0.05 0.03
## WWTR1 51.67 47.32 44.53 26.59 32.67 41.62 37.93
## AGPS 18.14 16.23 15.58 14.07 14.68 17.59 17.72
## CXorf56 22.87 23.10 21.12 20.73 23.18 24.50 30.61
## ATP1A2 0.07 0.06 0.13 0.10 0.07 0.26 0.07
## TTC27 21.78 21.37 20.59 19.74 19.29 26.86 22.28
## ZNF582 0.93 1.38 1.11 1.14 0.78 1.01 1.08
## VSIG2 0.54 0.59 0.31 0.59 0.28 0.47 0.31
## PHLDB1 20.52 17.56 18.75 13.80 6.53 15.45 9.84
## MARCO 0.09 0.05 0.00 0.06 0.00 0.19 0.02
## CYP24A1 1.78 0.91 1.06 0.67 0.45 1.27 0.19
## PRDM11 4.20 4.21 4.37 2.91 3.37 4.37 3.32
## SYT13 0.08 0.08 0.13 0.06 0.02 0.06 0.03
## SNAI2 40.94 24.28 24.72 40.37 40.31 37.31 55.15
## CD74 533.78 500.67 547.40 361.00 354.27 379.48 351.42
## HGF 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZRANB1 11.71 11.72 13.18 9.63 9.54 10.72 11.26
## NCDN 21.34 18.63 18.30 16.81 14.45 17.82 19.35
## GPR124 0.06 0.08 0.05 0.03 0.03 0.11 0.04
## ZFP64 6.01 7.79 7.55 4.98 4.98 6.56 6.84
## MNAT1 74.08 70.49 70.58 67.66 64.19 72.67 59.20
## SAMD4A 18.69 18.99 18.60 15.83 10.91 13.84 15.95
## RUNX3 0.07 0.02 0.04 0.00 0.00 0.00 0.00
## MRE11A 20.14 20.42 16.98 16.74 11.44 20.84 13.49
## PLEKHB1 1.26 0.44 0.67 0.78 0.61 0.46 0.39
## SERPINB1 153.83 174.69 193.17 97.41 82.52 113.58 83.83
## CYP3A43 0.00 0.07 0.04 0.00 0.00 0.02 0.00
## SLC7A9 0.10 0.09 0.20 0.11 0.22 0.11 0.21
## SPAST 3.94 4.56 4.78 3.35 4.50 4.55 5.61
## NRXN3 0.01 0.00 0.01 0.00 0.00 0.01 0.01
## OSBPL5 8.29 8.17 9.56 5.87 4.43 7.87 5.36
## AQR 21.72 20.25 16.88 19.33 20.41 19.62 24.19
## CPS1 0.89 0.96 1.10 0.62 0.66 0.63 0.62
## C8B 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## FHL1 2.74 2.38 2.99 1.94 2.39 1.88 2.42
## RTFDC1 140.49 139.21 138.79 131.77 127.29 141.66 139.86
## GABRA1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NLRP2 3.56 3.60 3.47 2.61 2.45 2.70 2.97
## SLC45A4 4.96 5.97 5.68 3.80 3.27 4.66 4.70
## RNF10 122.94 142.99 162.59 139.09 110.50 129.80 146.45
## ZNF839 14.50 15.76 15.57 14.41 11.89 12.80 17.84
## ZDHHC6 28.64 26.34 23.56 31.13 25.89 32.73 33.43
## GRAMD1B 0.32 0.71 0.68 0.10 0.03 0.18 0.04
## RNH1 172.82 174.41 170.37 194.66 162.25 185.52 200.75
## NDUFS1 40.23 42.09 38.86 27.17 24.77 36.96 33.96
## RB1CC1 15.31 19.06 19.90 10.81 14.24 15.46 18.89
## ERP44 28.04 28.14 28.89 27.72 28.41 30.37 28.85
## ALAS1 45.03 48.30 46.37 37.17 31.75 41.67 38.69
## BIRC3 32.49 39.80 33.85 9.18 10.19 13.40 8.96
## AKAP11 6.61 7.61 6.74 4.64 5.08 5.93 6.82
## GLRX2 42.59 35.03 34.24 51.32 49.03 54.80 45.34
## SNAPC1 46.89 35.11 32.27 41.88 41.41 43.68 63.57
## DERA 39.87 37.76 32.03 42.57 38.80 46.29 39.22
## STRAP 139.71 139.40 125.22 152.20 168.29 154.02 176.14
## ABCC2 0.32 0.50 0.46 0.51 0.88 0.48 1.25
## DEF6 15.64 15.70 14.49 10.89 9.90 13.65 11.00
## PLEKHO1 13.28 14.62 15.94 20.72 14.11 19.51 18.52
## GCLM 60.49 42.20 48.42 74.92 150.10 92.78 182.07
## UBR2 17.75 24.26 25.35 12.45 14.50 17.49 18.10
## EHD2 77.58 81.16 74.30 66.70 57.79 76.92 66.53
## DEPDC1 33.79 37.60 26.82 25.53 22.78 31.66 26.04
## CCDC28A 10.19 12.62 14.49 7.97 11.40 10.20 14.74
## RRAGD 7.94 8.75 9.30 12.59 17.13 14.52 26.83
## HSF2 16.78 16.58 15.81 15.14 14.34 16.16 14.20
## PHF20 14.97 18.36 15.40 11.94 14.38 14.79 17.28
## HSD17B6 0.62 0.49 0.51 0.36 0.53 0.30 0.41
## NR1H3 12.19 11.74 15.65 8.29 5.91 11.67 9.82
## TYMP 19.08 17.62 28.47 10.53 11.86 10.64 11.47
## NCAPH2 31.24 25.23 21.63 37.74 19.69 32.89 21.98
## TOMM34 140.28 149.35 118.51 176.94 126.08 170.27 166.89
## SEC63 40.85 36.50 41.88 37.72 34.61 44.14 35.77
## KPNA6 23.33 23.89 23.22 18.42 19.27 22.99 25.04
## VIM 2200.45 1989.94 1722.36 2413.10 1740.75 2452.49 2061.67
## RTEL1-TNFRSF6B 5.05 4.98 3.89 4.32 2.88 2.53 4.54
## FAS 3.46 4.33 3.49 4.00 3.89 4.25 4.24
## RNASET2 71.72 66.82 74.04 62.61 58.72 71.79 70.89
## CD44 1074.16 1061.18 952.04 832.68 792.74 924.52 757.18
## KCNG1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## AGPAT4 2.88 4.34 5.00 3.17 1.28 3.53 1.05
## SLAMF7 13.45 13.50 10.39 14.38 10.86 14.13 16.28
## BTN3A1 18.31 22.86 26.48 7.33 5.47 11.16 8.23
## MIPEP 8.05 9.53 8.84 6.65 5.87 10.25 9.87
## PRKCH 2.28 2.72 3.49 1.85 1.70 1.74 1.94
## INSRR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## IFNGR1 29.65 29.50 32.76 21.15 21.66 26.64 26.88
## B4GALT7 22.08 22.87 22.31 26.57 20.54 22.76 28.52
## SH2D2A 0.16 0.25 0.33 0.36 0.19 0.27 0.36
## VRK2 23.27 23.85 22.14 20.98 23.33 24.15 26.15
## TNFRSF1B 9.59 11.46 12.10 4.91 2.33 7.44 2.24
## VEZT 44.62 42.31 39.42 31.53 29.79 39.87 35.98
## POU2F2 2.14 3.12 1.89 2.34 0.84 2.08 0.58
## BRD9 53.04 52.63 48.55 51.44 47.23 52.20 54.01
## SNX1 39.66 38.16 38.22 33.05 24.78 36.69 29.56
## TBPL1 16.97 16.57 18.23 16.45 19.83 19.56 17.56
## ARNTL2 22.35 21.50 15.99 20.48 20.32 24.58 20.73
## BCLAF1 76.20 65.89 57.57 42.09 40.16 54.66 50.28
## SLC39A9 33.12 35.63 35.23 27.51 34.18 31.11 41.29
## ANK1 3.05 3.27 3.02 1.51 0.70 1.98 0.63
## IBSP 0.06 0.04 0.00 0.03 0.00 0.08 0.09
## TFB1M 6.82 6.90 7.43 6.33 3.91 7.45 4.40
## RABEP1 32.22 27.79 26.36 27.86 27.43 35.90 31.94
## HMGB3 152.01 195.92 184.42 107.17 88.21 131.90 98.57
## NUP160 26.62 23.80 20.78 22.38 23.36 26.27 25.90
## BAK1 53.60 57.45 64.22 56.31 56.20 62.14 66.50
## MUSK 3.52 4.63 3.32 2.78 1.37 2.49 0.60
## IKZF2 1.17 0.89 1.13 0.37 0.60 0.70 0.46
## GRN 304.34 285.72 296.51 286.10 315.93 316.64 457.45
## FAM13B 17.17 16.26 12.87 14.79 21.25 16.93 33.71
## ARHGAP31 2.30 2.31 2.27 1.70 1.76 2.48 2.63
## CENPQ 28.06 24.75 17.47 29.84 21.17 29.36 23.67
## SARS 150.39 145.90 146.31 170.60 178.27 163.87 244.48
## RANBP3 64.44 58.96 59.20 52.88 40.22 57.40 49.43
## ARID4A 4.53 6.06 6.65 3.14 3.76 5.14 5.73
## TSSC1 29.05 27.46 26.66 28.76 21.22 31.63 22.00
## PNPLA6 68.64 62.98 72.09 50.20 39.78 58.13 53.48
## IFT88 9.55 8.86 8.73 6.07 6.08 8.38 6.38
## ALG1 22.19 19.30 16.94 19.74 15.62 20.66 18.42
## ZCCHC8 19.53 20.22 19.87 19.77 22.41 19.06 25.55
## ABCF2 75.47 60.88 54.73 61.94 58.91 68.12 79.03
## CHPF2 51.54 50.82 54.30 41.84 40.32 47.64 44.02
## LRRC7 0.18 0.14 0.19 0.10 0.11 0.10 0.06
## FUT8 62.31 59.81 57.93 46.56 29.71 58.39 31.00
## UBA6 23.83 21.08 17.88 15.65 16.45 19.27 21.59
## GAB2 4.40 5.01 4.47 4.76 4.06 5.34 7.10
## ATP6V0A1 21.67 21.65 22.31 24.51 34.53 25.90 49.10
## PIAS1 11.03 11.76 11.02 8.04 6.44 8.98 7.95
## SLC4A7 11.84 11.96 9.43 8.59 9.47 9.62 12.88
## APBA2 8.35 9.08 7.09 10.38 8.58 10.44 11.51
## MAP2K3 70.70 71.49 74.73 64.05 51.22 71.11 59.49
## EFCAB1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TMSB10 4759.64 4460.29 4578.03 5301.79 5545.57 5468.02 5178.89
## ASTE1 3.31 2.84 2.76 2.62 2.90 3.91 3.69
## RNF19A 20.98 17.42 18.17 12.01 16.51 14.25 21.55
## PEX3 15.95 15.04 14.83 16.87 16.01 18.98 17.99
## GABARAPL2 62.31 66.27 80.12 51.20 45.11 62.88 40.12
## MYOC 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## SH3YL1 7.71 6.27 6.65 6.16 8.89 8.38 12.38
## FAM136A 71.90 68.07 59.01 76.27 70.34 83.29 69.98
## VCL 111.42 126.58 104.57 92.36 95.48 111.37 117.68
## DEPDC1B 12.13 15.63 11.96 12.34 7.14 13.20 7.35
## DAPK2 3.00 3.43 5.29 1.53 1.18 1.95 1.40
## NSMAF 22.96 23.82 21.50 20.93 19.23 24.07 27.80
## ADSS 48.03 47.66 44.36 45.87 50.59 51.42 71.41
## STAP1 0.00 0.00 0.00 0.00 0.04 0.00 0.02
## TIMP2 383.18 378.76 356.58 363.80 345.30 416.91 462.19
## RFC1 34.14 29.85 25.18 25.08 22.95 30.23 27.08
## TBC1D23 31.99 34.52 33.72 28.38 30.20 31.94 35.25
## CUL3 61.95 60.78 64.86 54.54 63.75 62.01 63.20
## MYOM2 1.53 1.71 2.62 1.68 3.66 1.81 4.43
## OTC 0.06 0.00 0.00 0.00 0.02 0.00 0.00
## CYP46A1 0.10 0.08 0.09 0.06 0.04 0.10 0.24
## ZZZ3 36.26 35.48 35.83 31.53 44.59 39.64 53.75
## SLC18A1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## USP2 0.25 0.19 0.24 0.26 0.10 0.12 0.44
## CASR 0.00 0.01 0.01 0.00 0.00 0.00 0.00
## TUBG2 12.71 15.53 16.33 8.84 6.49 9.03 8.53
## RPL26L1 98.19 87.95 87.19 103.17 119.06 106.16 108.90
## FLT4 0.01 0.00 0.00 0.00 0.00 0.00 0.01
## NSUN2 81.01 63.57 63.70 70.66 64.93 66.76 74.13
## FBXO42 9.02 11.21 11.70 9.85 9.15 10.05 11.40
## MFAP3 14.31 16.73 15.20 12.41 16.25 13.78 21.14
## MRI1 13.65 14.76 15.12 12.11 7.96 11.61 10.74
## METTL1 33.55 26.63 24.67 34.57 22.39 31.49 25.12
## HOXC8 0.29 0.29 0.43 0.26 0.30 0.47 0.32
## AGA 28.06 26.30 26.77 20.06 22.01 24.99 24.72
## PI4K2B 24.82 27.75 21.85 20.53 18.16 25.33 19.57
## BOD1L1 17.16 19.36 17.80 13.17 15.71 15.64 23.80
## MAT2B 57.07 69.20 76.12 48.60 46.69 60.00 57.50
## TLL1 0.00 0.00 0.00 0.00 0.19 0.00 0.00
## EDC4 31.80 30.06 24.52 30.87 28.48 23.25 40.27
## TRIO 49.92 51.22 51.33 49.33 63.43 44.14 73.97
## VCAN 0.09 0.03 0.08 0.10 0.35 0.09 0.23
## CLEC16A 7.53 7.17 6.88 5.73 5.24 7.27 6.38
## MSR1 0.09 0.19 0.18 0.26 0.09 0.07 0.16
## CDH1 0.20 0.13 0.34 0.19 0.19 0.21 0.56
## SKIV2L2 15.90 16.51 13.55 13.53 11.99 15.90 15.49
## DNAH5 4.56 5.13 5.23 3.48 2.99 4.06 2.04
## ZFYVE16 10.78 12.04 11.96 8.84 9.93 12.06 14.09
## FAM65A 51.24 43.40 40.44 46.78 40.68 50.71 49.15
## C6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RAI14 55.46 47.45 45.65 50.28 60.37 54.70 75.36
## SOX30 0.01 0.03 0.06 0.01 0.06 0.15 0.05
## PNKP 32.65 31.48 33.13 33.73 25.48 27.92 33.49
## BEST2 0.05 0.02 0.01 0.00 0.01 0.00 0.19
## PHLPP2 3.78 3.71 3.06 3.30 4.49 3.73 5.95
## SPDL1 53.06 48.55 36.77 49.38 36.68 52.58 40.33
## STAU2 11.48 13.17 13.52 8.17 7.23 12.66 9.67
## PQLC2 25.17 23.24 22.45 31.44 27.57 28.44 36.04
## CTNS 9.15 8.75 10.73 10.68 11.52 11.47 17.95
## RTN4R 1.35 1.19 1.11 1.59 1.38 2.28 2.55
## PHF23 42.01 40.60 48.81 35.15 34.87 42.70 36.96
## CDH10 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## INPP4A 7.91 8.46 8.61 6.15 5.49 7.32 8.00
## RAB27B 9.28 11.04 11.76 6.89 10.07 10.95 15.08
## PSMA4 175.32 166.04 172.71 150.84 123.22 172.19 107.15
## MYO16 0.25 0.27 0.36 0.10 0.22 0.24 0.31
## LSG1 27.07 25.32 21.19 25.82 30.32 25.35 40.13
## PARP3 16.73 19.19 19.94 10.46 13.54 11.56 16.36
## TNC 20.51 16.25 13.59 10.40 6.69 11.90 10.42
## THAP3 18.12 18.38 23.48 17.91 18.05 18.99 22.98
## FAM65C 0.17 0.17 0.23 0.25 0.21 0.30 0.12
## TDP1 28.82 28.60 23.19 29.52 22.90 31.28 22.55
## AIFM2 19.87 19.53 19.21 21.89 24.01 24.17 28.48
## C2orf83 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SPATA7 4.17 4.98 5.82 3.53 3.38 4.68 3.75
## MED17 63.29 63.07 68.89 53.84 57.30 62.17 71.78
## RETSAT 30.12 32.48 32.61 23.50 21.30 29.14 30.72
## CAPG 425.56 396.32 423.30 458.73 402.54 478.15 452.59
## AP2S1 373.24 359.42 350.53 446.50 399.11 410.91 340.50
## USH2A 0.00 0.00 0.01 0.00 0.00 0.01 0.00
## ZPBP 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TG 0.02 0.06 0.01 0.11 0.32 0.01 0.27
## ADAM28 1.53 1.23 1.57 0.70 0.32 1.09 0.70
## BARX2 0.70 1.06 0.93 0.80 0.40 0.83 0.57
## DCUN1D1 20.48 21.04 21.56 16.60 22.49 18.92 27.53
## JADE2 16.29 21.15 22.18 10.41 9.12 15.97 13.90
## ZIC2 3.69 3.83 3.47 4.14 3.37 4.51 3.86
## LCP2 0.00 0.01 0.00 0.09 0.05 0.00 0.06
## TRIT1 22.38 20.46 21.98 17.07 15.14 20.55 15.18
## ADRB1 0.09 0.14 0.13 0.07 0.08 0.07 0.11
## GUCA2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CUL7 21.81 25.46 27.21 12.02 11.89 12.66 14.85
## CTNNA1 340.32 358.37 340.54 261.41 312.31 336.60 357.13
## PHKA2 11.80 12.26 12.23 9.64 8.38 8.61 11.03
## CNTLN 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## EPHA3 0.00 0.02 0.00 0.01 0.00 0.01 0.00
## HSPA5 947.00 898.38 1124.84 867.58 825.91 922.58 917.00
## DSG2 34.89 37.10 28.24 38.98 41.07 46.37 70.39
## GEMIN8 13.75 14.73 18.71 15.88 16.40 17.62 17.53
## OFD1 22.08 22.79 25.20 18.90 21.99 18.95 26.00
## GPM6B 0.23 0.24 0.18 0.14 0.11 0.20 0.27
## MAGEC2 0.51 0.49 0.38 0.44 0.35 0.34 0.34
## PREX2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## WDR37 16.22 16.86 15.99 17.14 22.56 16.82 27.95
## YTHDC2 8.10 8.87 7.28 5.77 5.92 6.30 8.47
## CTPS2 7.39 8.42 8.20 6.66 5.91 8.22 5.92
## ATP6V1H 29.56 33.63 32.60 31.36 42.98 38.15 65.37
## POLR2B 91.34 94.42 90.14 76.19 83.56 89.46 98.55
## FAM214A 3.05 5.76 5.74 2.68 4.63 3.84 6.43
## ARAP2 2.30 2.01 2.42 2.41 2.43 2.27 3.08
## TPR 39.70 44.23 39.00 35.01 33.70 40.80 53.34
## CP 0.10 0.24 0.19 0.06 0.11 0.11 0.22
## KIAA0556 4.96 6.16 4.54 3.08 3.80 4.23 4.70
## DTNBP1 25.88 25.46 24.90 29.73 26.92 31.57 33.20
## XK 1.24 1.59 0.98 1.24 1.12 1.58 1.60
## ANO2 0.05 0.08 0.01 0.01 0.00 0.00 0.00
## C12orf4 10.72 9.16 8.16 10.62 12.95 12.70 16.29
## SCML1 22.51 21.50 18.69 24.35 30.85 25.34 38.16
## WWC3 26.66 28.53 29.98 21.69 22.89 25.08 26.02
## ARHGAP6 0.02 0.00 0.00 0.00 0.00 0.00 0.00
## FAM184B 0.58 0.75 0.64 0.58 0.38 0.60 0.49
## MAP4 131.96 130.26 113.56 115.52 96.35 131.20 117.67
## GOPC 10.66 11.30 11.54 8.08 10.48 11.01 10.75
## ROS1 0.00 0.01 0.01 0.00 0.00 0.00 0.00
## USP28 21.20 17.38 17.33 12.73 13.52 16.91 15.80
## HDAC9 18.21 16.75 16.67 24.82 36.28 27.99 51.55
## TSPAN17 50.08 49.74 49.60 49.97 47.62 52.72 55.45
## NOP16 83.19 61.30 58.17 87.94 81.16 82.49 78.87
## CC2D2A 10.20 9.25 9.20 7.40 6.50 8.73 7.42
## RRM2B 13.70 18.01 18.27 10.54 15.14 14.91 19.57
## ZNF800 15.55 12.83 11.57 10.26 13.54 11.65 16.16
## TNFRSF17 0.03 0.00 0.00 0.00 0.05 0.00 0.00
## SNX29 2.15 2.61 2.50 1.86 1.67 2.32 2.48
## LMO3 0.03 0.06 0.11 0.00 0.09 0.04 0.03
## MRPS10 198.79 196.40 189.77 201.09 187.32 224.89 200.64
## GUCA1A 0.00 0.01 0.01 0.00 0.00 0.00 0.02
## RSF1 12.19 15.19 13.78 8.85 10.40 12.41 13.46
## VPS13D 7.18 8.52 9.72 5.59 7.17 8.20 6.97
## CELF2 2.75 2.90 1.80 3.30 3.28 3.09 5.51
## FAM120A 86.84 85.38 73.54 72.95 74.52 89.51 94.52
## R3HDM1 15.94 13.35 11.31 13.17 11.53 17.73 14.21
## COL9A2 5.46 5.63 6.35 6.19 4.62 6.33 5.50
## KITLG 19.88 14.88 17.12 12.38 19.30 17.86 25.62
## ERCC8 11.59 11.05 10.83 10.06 10.36 10.05 10.80
## ADAMTS6 1.70 1.41 0.91 1.37 0.31 1.21 0.35
## H6PD 16.58 21.33 21.99 7.61 6.46 10.37 7.26
## VAMP3 118.51 125.33 116.31 113.99 140.20 123.85 152.81
## PER3 7.37 8.61 7.92 4.72 2.30 6.26 3.92
## UTS2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TNFRSF9 3.36 3.34 4.35 1.13 0.64 0.84 1.20
## EPN3 0.88 0.37 0.54 0.12 0.16 0.41 0.28
## LTBP1 34.22 37.78 40.42 14.71 14.26 24.76 13.40
## RCN1 404.95 371.15 396.12 330.88 333.27 370.19 313.35
## ELN 0.00 0.02 0.10 0.04 0.02 0.00 0.07
## RFC2 77.42 59.21 45.04 77.92 51.26 78.91 49.58
## ARID1B 3.72 4.42 3.82 2.66 3.15 3.02 3.82
## CLPTM1L 182.43 155.94 159.91 169.75 147.91 185.35 133.84
## NEDD4L 65.63 56.81 41.85 85.43 70.68 72.98 107.78
## FOXP3 0.15 0.14 0.15 0.12 0.12 0.15 0.30
## PPP1R3F 13.07 13.36 16.60 12.18 8.04 14.29 7.48
## HEXB 188.49 181.44 202.43 203.71 212.17 255.01 248.38
## PTCD2 5.12 5.40 5.22 4.64 5.20 5.82 7.08
## KIAA2022 0.03 0.02 0.09 0.03 0.02 0.02 0.01
## JKAMP 88.04 87.66 93.05 76.63 89.43 90.39 102.33
## DKK3 1.16 1.16 1.16 1.21 1.35 1.35 1.69
## ARHGEF5 5.79 6.36 5.26 4.95 6.17 5.46 10.31
## NFE2L3 86.69 78.03 75.34 63.68 41.58 75.08 31.00
## MCUR1 48.53 47.87 43.20 59.54 65.01 56.52 66.24
## LIMA1 88.23 99.85 79.22 84.56 65.54 89.98 60.43
## LETMD1 32.20 33.97 33.67 32.31 28.70 30.18 34.65
## SLC4A8 0.83 0.56 0.52 0.41 0.46 0.51 0.79
## LAMC3 0.00 0.00 0.00 0.01 0.00 0.01 0.01
## PTGER3 0.03 0.01 0.01 0.01 0.01 0.00 0.02
## TNIP3 0.95 0.64 0.51 0.76 1.41 0.53 1.63
## MAPK9 38.14 39.88 38.75 31.47 23.40 43.10 26.95
## COL23A1 0.01 0.00 0.01 0.01 0.00 0.01 0.00
## BCAR1 52.54 51.93 53.02 40.85 37.07 45.28 43.51
## FAM160A2 14.91 15.54 14.76 15.54 17.11 12.69 23.02
## HERPUD1 68.64 66.35 151.26 57.96 95.91 53.37 110.93
## HOMER3 54.23 50.66 52.93 59.03 46.05 64.09 53.10
## RAD51 24.77 18.35 13.43 25.91 18.84 29.93 17.47
## POLQ 2.63 2.13 1.51 2.31 1.81 2.31 3.00
## PIK3CB 18.71 20.99 21.33 13.26 14.69 17.56 16.42
## CYBA 136.13 131.73 151.17 154.80 129.75 140.51 117.78
## THOC3 54.59 53.01 50.46 52.88 42.72 57.89 48.39
## HEBP2 83.35 83.67 94.14 87.73 93.60 94.53 81.31
## MPHOSPH9 25.01 28.20 23.00 21.31 15.86 22.33 20.24
## PLEKHA5 24.90 23.98 25.34 20.44 19.74 22.67 20.87
## PRSS8 0.12 0.17 0.15 0.28 0.31 0.37 0.79
## SIKE1 34.63 33.79 34.74 29.25 30.12 30.50 29.46
## RRP12 33.42 28.52 23.80 35.56 31.97 33.90 41.51
## FNIP2 4.66 4.78 4.22 5.61 9.20 7.22 15.82
## MSMO1 47.07 37.93 45.28 67.06 68.84 71.18 116.51
## TTC17 39.79 46.92 43.81 34.74 33.16 41.46 38.20
## ALX4 0.02 0.01 0.02 0.00 0.00 0.01 0.00
## FSTL4 0.04 0.06 0.08 0.08 0.01 0.02 0.01
## FOXN3 12.05 14.05 12.30 10.67 9.19 13.99 12.73
## METTL24 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## AKR7A2 74.68 72.07 78.67 74.72 59.44 73.35 60.53
## MRTO4 86.01 63.56 54.44 90.60 69.80 84.50 67.05
## NNAT 0.83 0.80 0.95 0.67 0.73 0.64 1.51
## USE1 23.04 23.14 25.53 21.52 15.52 19.80 17.07
## MCF2L2 0.43 0.77 0.37 0.43 0.35 0.32 0.30
## NRIP2 0.22 0.18 0.13 0.17 0.14 0.19 0.26
## LAMA3 25.55 29.87 29.03 17.33 14.45 23.03 18.60
## AP5M1 18.58 20.14 19.53 14.83 16.43 18.94 23.02
## ANAPC4 17.23 19.46 16.82 14.80 16.87 16.49 17.41
## KCNQ1 0.88 0.39 0.33 0.20 0.26 0.43 0.62
## TRAPPC3 123.54 111.63 128.21 113.49 119.84 122.27 121.36
## THRAP3 70.45 71.67 61.68 56.64 50.44 60.82 72.90
## PHPT1 142.08 134.32 146.07 134.58 120.81 132.72 110.63
## ENTPD2 0.20 0.10 0.11 0.07 0.37 0.11 0.61
## LY75 3.16 3.34 2.71 2.01 1.99 2.47 2.78
## ARID4B 8.65 11.43 12.26 5.76 8.90 9.48 11.30
## OPN3 8.45 7.69 7.93 6.61 5.46 7.97 4.26
## SDCCAG8 13.51 12.68 11.91 10.51 9.93 12.78 9.40
## PTPRN 0.01 0.00 0.00 0.00 0.07 0.00 0.00
## HHAT 4.14 3.83 4.01 3.04 2.41 3.42 3.28
## KIF1B 8.28 10.33 9.76 7.07 9.10 8.36 12.28
## FOXC1 11.22 11.03 10.47 11.32 8.63 12.22 13.82
## TBC1D22A 11.35 11.26 11.26 10.15 7.87 10.33 9.05
## SYNE2 8.70 10.79 10.40 8.68 6.92 8.75 7.57
## PLEKHH1 2.41 3.04 2.48 2.66 1.43 2.09 2.77
## ATP9A 3.49 4.97 4.97 2.63 4.79 3.35 6.27
## SPO11 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CBLN4 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## CHRDL2 0.30 0.73 0.59 0.12 0.97 0.21 1.35
## FAM168A 14.57 17.30 15.98 8.56 6.51 12.60 7.25
## RELT 13.19 10.26 8.03 16.04 16.30 12.67 17.70
## GALC 17.01 19.74 19.62 13.05 14.20 16.54 18.56
## NOP58 90.00 70.44 62.50 82.21 85.69 84.26 97.05
## SZRD1 154.62 144.85 124.54 146.97 132.32 160.77 155.08
## KCNH2 0.01 0.00 0.01 0.04 0.01 0.02 0.03
## CUL1 48.11 46.81 46.66 40.54 47.71 47.15 51.10
## FAM114A2 12.22 14.47 15.12 11.66 16.73 14.77 21.69
## CYFIP2 1.58 3.21 2.11 1.61 1.54 2.15 1.91
## TAB2 33.07 34.47 35.00 21.91 22.85 28.24 26.10
## GINM1 38.31 40.67 39.87 37.90 43.31 44.76 42.42
## EIF2AK2 20.87 20.22 18.18 14.67 13.81 17.64 18.97
## USP36 32.67 30.37 23.64 36.58 45.34 37.53 83.97
## KMT2C 6.57 8.09 8.93 5.46 6.55 5.54 6.68
## MCOLN3 2.15 2.06 2.14 2.80 2.98 2.68 5.44
## CCDC85A 0.01 0.01 0.02 0.01 0.01 0.02 0.01
## PUM2 28.34 31.91 33.91 22.29 28.09 29.81 34.19
## MRPL43 102.29 92.77 103.73 101.35 85.21 104.41 86.90
## ITIH4 9.38 12.43 16.75 2.93 2.54 3.54 3.36
## ITIH1 0.01 0.00 0.00 0.00 0.00 0.00 0.00
## C4orf27 38.99 34.94 33.15 34.63 26.66 42.00 24.22
## ZFR 58.57 57.49 51.04 41.46 65.65 53.46 94.77
## ZNF280C 2.43 2.41 1.75 1.73 2.20 2.29 3.06
## NPFFR2 0.03 0.00 0.00 0.00 0.00 0.03 0.00
## PHF21B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TRAF1 13.28 14.34 13.76 7.87 8.41 7.93 12.22
## RC3H2 19.44 30.82 28.00 14.74 20.43 15.85 29.19
## PCGF2 33.76 30.08 30.12 29.68 24.90 32.80 30.47
## IL17RB 0.89 0.92 1.03 0.71 0.85 0.84 0.60
## TRAF3IP2 15.09 16.00 13.87 12.82 11.97 13.28 22.68
## GYG2 1.96 1.54 2.40 0.82 0.45 1.09 0.46
## DCBLD2 98.69 94.63 75.97 96.39 92.59 111.18 117.62
## SERPINB3 0.18 0.22 0.23 0.03 0.00 0.05 0.00
## SOAT1 78.99 67.71 53.56 79.83 84.01 100.37 122.41
## PKP2 14.88 14.18 10.69 12.49 11.35 13.79 11.11
## MSH4 0.06 0.08 0.03 0.03 0.09 0.05 0.06
## F7 0.01 0.00 0.01 0.01 0.00 0.03 0.02
## GDI2 257.79 237.93 226.12 246.72 249.90 283.44 263.39
## PRDM1 0.86 1.32 1.23 0.35 0.26 0.73 0.39
## ATG5 22.69 21.49 21.94 18.60 21.10 23.84 20.55
## TMCC3 7.57 9.95 9.82 6.63 6.87 10.20 9.14
## PITHD1 67.52 63.34 62.75 86.64 90.04 81.78 112.92
## MTA3 20.95 20.39 20.31 14.21 13.16 18.85 14.93
## USP13 11.52 13.49 8.59 9.57 8.92 11.61 11.37
## ATP11B 20.67 25.26 23.45 16.43 19.41 19.75 26.65
## LAMC2 27.52 30.50 25.55 21.51 15.63 24.46 22.73
## CDK14 4.13 4.51 3.65 2.98 2.23 4.07 3.06
## SEC61A1 166.54 156.97 149.01 163.46 147.89 183.51 192.44
## PPP1R12A 27.84 26.38 25.81 20.36 21.02 24.20 28.94
## RASGRF1 2.24 1.85 1.91 2.53 2.25 2.01 5.23
## CAMK2B 0.48 0.62 0.52 0.30 0.30 0.25 0.16
## CROCC 4.37 5.45 5.37 5.05 5.21 5.38 7.96
## POLR3E 17.78 17.35 15.79 19.67 12.83 15.19 14.03
## ATP2B4 33.85 40.72 35.84 24.50 19.35 31.38 22.07
## ZC3H11A 54.26 58.42 66.61 41.50 46.99 44.20 49.55
## RIOK2 34.49 29.28 28.90 31.14 38.71 34.19 40.59
## YIPF1 31.57 32.01 35.58 28.76 32.66 34.37 32.38
## NDC1 29.75 29.96 23.58 27.45 20.40 33.87 23.46
## DGKG 0.09 0.10 0.06 0.17 0.03 0.01 0.07
## FLYWCH1 13.10 14.83 16.53 14.96 18.98 15.45 27.45
## UNKL 9.19 8.73 11.14 9.76 8.51 9.88 8.11
## TBXAS1 16.84 16.98 16.80 14.59 11.98 17.68 10.81
## PARP12 34.10 36.88 42.22 23.45 20.42 27.64 23.14
## ALDH18A1 48.58 43.82 38.37 38.99 35.92 42.64 49.80
## TARBP1 14.04 15.00 13.77 10.92 10.54 10.64 13.89
## PET112 17.12 17.63 17.30 15.91 16.28 16.94 18.29
## MXD1 3.41 4.37 5.59 4.15 11.66 5.03 17.17
## CDK17 17.37 16.87 15.54 15.87 22.55 18.24 26.56
## DNAJC25 36.31 38.01 70.31 67.11 66.14 67.78 60.43
## SLC2A3 18.20 21.43 26.57 30.24 48.54 36.99 64.36
## PSD 1.00 1.23 1.04 0.66 0.83 0.74 1.06
## CTDP1 8.03 8.16 8.71 7.71 7.23 7.65 9.02
## YBX3 189.77 182.90 186.89 200.50 224.03 200.53 244.98
## STYK1 6.04 4.53 3.38 5.86 10.25 4.62 12.79
## WNK1 27.52 30.57 27.94 22.06 26.96 25.99 35.14
## CCAR1 48.55 53.73 46.38 44.82 50.96 51.23 62.13
## OGFR 64.71 64.84 74.87 40.37 35.22 51.16 37.74
## GNA15 33.22 33.78 33.38 28.28 18.90 29.39 14.13
## CREB3L3 0.50 0.80 1.18 0.05 0.06 0.31 0.02
## PIGV 15.09 15.86 18.23 10.47 9.05 12.28 10.81
## PTPRU 12.63 13.11 13.73 9.00 6.50 12.10 9.89
## SNRNP40 61.51 56.94 46.66 67.94 56.72 67.68 53.99
## RIMBP2 0.00 0.01 0.00 0.01 0.00 0.00 0.01
## COL11A1 0.04 0.00 0.00 0.11 0.04 0.00 0.01
## QSER1 11.23 12.12 9.90 8.37 11.96 10.60 13.95
## MPC1 49.37 47.57 47.21 46.50 49.06 55.19 53.40
## ACAA1 35.35 34.51 38.65 36.32 35.78 36.14 41.34
## BCAT1 17.90 15.05 14.92 15.06 12.73 18.16 19.37
## HDAC7 28.32 24.78 26.83 28.61 25.99 24.78 32.53
## LZTS1 0.49 0.44 0.29 0.35 0.14 0.37 0.13
## PRDM6 0.18 0.08 0.18 0.11 0.23 0.14 0.82
## WNT8A 0.00 0.00 0.00 0.00 0.00 0.00 0.02
## SPAG4 14.29 15.60 16.73 11.05 11.23 12.14 12.86
## NCKAP1 79.60 82.45 81.01 68.29 83.11 82.56 102.67
## MRPS35 55.43 55.21 52.99 57.11 58.40 60.91 64.16
## GUCY1B3 0.71 0.66 0.46 0.59 0.48 0.70 0.75
## SFSWAP 21.69 20.39 19.00 18.26 16.01 19.07 23.87
## TNK2 15.75 19.56 20.69 18.85 13.07 18.70 21.15
## MON2 7.26 8.03 8.42 4.35 5.43 6.07 8.80
## CDH3 0.20 0.31 0.34 0.25 0.20 0.34 0.48
## ARSF 0.05 0.03 0.04 0.01 0.00 0.02 0.00
## GPBP1 53.77 56.45 58.11 42.73 50.18 50.95 50.80
## DGAT2 7.19 8.24 6.87 5.43 3.84 6.33 4.37
## ZNF112 2.37 2.42 2.37 1.61 1.86 2.08 2.44
## CS 95.53 94.21 80.92 89.89 71.14 90.21 81.29
## LTK 1.02 1.11 1.55 0.72 0.81 0.80 0.93
## MRPS24 162.57 161.07 175.79 194.23 154.13 183.52 141.97
## ELMO2 26.94 28.52 27.36 25.62 27.86 29.14 35.41
## WAPAL 23.18 23.82 21.44 17.74 21.90 21.70 27.95
## VMP1 135.84 136.73 153.11 111.48 104.58 112.52 112.26
## APPBP2 10.20 13.40 14.67 7.41 8.89 9.74 12.15
## POLD1 54.20 39.66 31.80 60.87 27.82 53.30 19.12
## SEZ6 0.04 0.05 0.02 0.01 0.04 0.00 0.00
## EIF4B 115.64 124.10 126.19 91.55 110.57 113.64 147.63
## SLC6A16 0.41 0.30 0.48 0.34 0.30 0.68 0.43
## GLTSCR1 4.13 5.80 5.63 4.21 5.96 4.79 7.29
## SPHK2 10.46 10.73 10.88 9.89 10.36 9.92 15.02
## RPL18 1781.67 1747.18 1827.19 2158.78 1996.88 1883.13 1995.30
## CA11 5.71 9.50 10.02 6.17 8.01 6.40 6.66
## ISOC2 60.00 55.09 58.98 65.20 52.85 57.18 54.02
## U2AF2 160.04 152.87 134.23 158.47 126.23 158.24 131.42
## EPN1 102.91 93.03 90.92 98.30 70.51 104.69 73.45
## MED29 26.52 28.76 28.81 24.61 24.17 27.19 34.46
## AHRR 1.33 2.48 2.54 0.82 0.58 0.73 0.44
## GSC2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZNF275 3.55 4.20 3.23 3.46 4.22 3.24 6.84
## MTMR1 22.46 23.60 19.32 19.69 15.36 21.57 19.39
## GPC1 66.06 56.53 57.11 65.73 64.69 72.76 64.60
## ADCK1 1.24 1.39 1.75 0.73 0.57 1.11 1.02
## HAGH 60.75 68.23 70.13 51.09 36.13 58.65 34.70
## RNF4 51.11 52.79 48.90 49.19 53.77 52.14 66.56
## CASP8 23.48 25.23 23.80 17.31 16.68 19.20 21.26
## LIMCH1 44.97 41.29 41.79 33.22 42.69 41.38 46.04
## ASUN 28.78 24.58 24.22 25.75 24.57 29.27 22.68
## TM7SF3 23.71 26.03 28.38 22.56 24.23 27.51 29.00
## DLX3 0.18 0.46 0.33 0.19 0.23 0.15 0.53
## SPA17 39.67 40.20 38.74 33.83 29.44 41.93 20.42
## TSPAN32 0.10 0.12 0.09 0.04 0.03 0.00 0.00
## WISP2 0.90 1.26 1.73 0.60 0.60 0.68 1.08
## DMRT3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ST3GAL6 12.42 12.38 14.48 11.98 10.16 14.73 14.77
## ATP2C2 0.68 0.49 0.90 0.36 0.55 0.74 0.61
## NGFR 1.38 1.11 1.22 0.79 0.71 0.93 1.17
## CDON 5.11 7.36 7.57 2.86 3.94 5.39 5.56
## TAF2 12.35 13.77 12.40 9.57 11.03 11.91 11.41
## HIPK2 18.38 25.26 22.09 16.29 18.43 21.39 19.79
## TNPO3 33.34 32.17 27.50 29.97 30.12 34.76 40.59
## MEF2BNB-MEF2B 2.24 2.56 2.58 2.85 3.33 2.54 4.57
## RFXANK 71.09 63.21 73.27 61.13 50.91 68.00 39.36
## TMEM161A 25.10 20.98 19.67 22.90 18.63 20.81 25.86
## LPAR2 5.22 4.52 4.85 3.93 3.61 3.14 5.00
## CTSA 226.84 203.80 225.57 212.20 221.56 239.92 363.80
## SUGP2 50.54 50.42 47.11 55.13 41.86 47.91 43.81
## SLC12A2 6.66 6.93 6.77 5.09 5.59 5.89 7.41
## SNX24 33.08 24.99 23.85 29.67 27.52 28.31 27.38
## EYA2 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## CNN2 187.36 161.89 149.92 190.92 157.11 167.84 163.07
## ABCA7 5.40 6.81 7.25 3.73 3.28 5.09 4.37
## SNCAIP 0.25 0.36 0.29 0.36 0.07 0.30 0.10
## DDX20 14.26 12.52 10.99 12.01 11.18 14.29 13.26
## BTBD1 38.29 38.94 38.87 32.03 33.19 38.44 42.43
## FAR2 0.58 1.03 0.70 0.29 0.46 0.29 0.28
## BCAS1 0.18 0.17 0.26 0.04 0.01 0.14 0.02
## POU1F1 0.00 0.00 0.00 0.02 0.00 0.00 0.00
## CHI3L2 7.27 5.25 9.71 2.40 2.32 2.94 2.66
## SBNO2 39.24 47.91 45.52 34.08 30.94 36.60 38.64
## PMS1 10.32 8.05 7.74 9.22 7.07 9.30 8.54
## HMG20B 141.43 153.88 169.87 138.31 110.95 141.12 106.59
## CALCRL 0.00 0.08 0.02 0.01 0.01 0.02 0.06
## TAF11 34.26 33.00 34.37 29.70 28.08 31.00 32.68
## ANKS1A 6.86 8.26 8.44 4.72 4.97 6.62 7.46
## AP3D1 55.04 52.34 51.88 52.14 46.51 55.55 64.08
## ZNF76 49.13 52.72 54.43 44.18 33.71 44.27 46.44
## SLC9A3R2 208.17 210.97 207.77 201.19 128.01 229.63 103.42
## NTHL1 20.16 18.06 21.26 13.45 8.48 17.55 6.95
## UHRF1BP1 7.98 9.61 9.06 6.50 8.65 7.41 12.64
## GNAI3 81.65 80.87 75.14 77.64 81.49 87.76 94.38
## IPO5 94.54 91.31 71.41 85.17 74.85 98.41 92.38
## OAT 120.06 127.39 134.22 108.85 117.27 120.75 140.57
## WDR3 41.04 37.56 30.31 37.53 40.75 40.93 54.73
## PKN2 16.29 19.47 17.76 12.29 14.97 16.04 19.13
## WDR18 39.13 39.51 41.41 48.09 38.74 40.90 42.80
## TRAM2 74.58 66.87 54.59 67.07 65.94 74.79 93.07
## NTN1 0.03 0.03 0.03 0.03 0.04 0.03 0.05
## GLP2R 0.26 0.20 0.30 0.15 0.23 0.11 0.35
## MCM10 21.82 14.76 7.88 16.71 11.20 19.33 13.41
## DGKA 9.47 13.56 14.63 8.67 5.33 11.39 5.04
## ERBB3 2.60 2.70 2.87 1.23 0.97 1.60 0.52
## ROPN1 0.00 0.00 0.06 0.05 0.00 0.00 0.02
## ANKRD44 2.30 1.74 1.61 1.24 1.34 1.82 1.10
## KARS 132.70 116.81 100.92 130.89 114.29 139.49 129.59
## ADAT1 24.89 23.50 19.54 18.85 15.89 21.58 17.35
## PDIA5 17.39 18.05 20.70 14.56 10.31 13.94 11.87
## TBC1D22B 16.57 17.74 17.04 16.24 15.31 18.03 18.79
## NDUFB4 179.37 176.43 197.43 171.71 183.88 189.86 127.44
## SPEN 21.15 21.99 19.93 12.97 15.82 16.49 18.47
## MYLK 15.57 15.40 13.03 10.50 6.66 14.40 7.41
## ZC3H15 65.67 54.65 52.75 56.93 60.64 65.21 68.09
## MAP2K4 28.58 29.39 30.69 23.95 31.09 30.80 35.11
## TMEM206 13.95 10.94 11.78 18.53 22.76 21.03 24.79
## SNAP91 0.63 1.06 0.93 0.79 0.88 1.37 1.44
## SLK 29.37 33.54 30.18 20.93 26.20 28.33 32.82
## CYB5R4 18.21 17.91 19.64 16.21 18.95 19.71 20.64
## COL17A1 8.21 6.44 5.19 5.32 2.79 7.67 6.05
## GSTO2 1.24 1.38 1.33 1.42 2.11 0.79 2.31
## SEC61A2 6.74 6.84 5.91 6.92 7.18 5.82 9.67
## PRKCQ 0.15 0.12 0.11 0.08 0.02 0.12 0.04
## TLE2 0.70 0.31 0.56 0.34 0.12 0.37 0.23
## ASB1 46.34 43.93 40.65 47.09 35.01 41.27 45.61
## FAM107B 87.27 85.79 81.38 60.89 74.97 69.27 73.75
## ME1 23.78 19.91 22.70 19.89 22.64 24.09 26.80
## TBC1D1 38.45 37.96 34.54 36.38 24.34 36.67 24.61
## CDK13 11.46 13.45 15.21 9.65 11.71 11.66 14.20
## MTHFD2 43.61 33.39 32.50 46.56 58.41 44.21 75.55
## SLC9A7 11.06 13.94 13.04 5.07 5.50 7.69 6.22
## FOXJ2 8.48 10.60 10.00 6.97 7.80 8.57 11.49
## YBX1 886.41 802.54 736.25 894.76 885.74 972.91 844.73
## PDE4A 14.81 15.33 15.27 11.83 7.29 14.35 6.99
## PPP2R5A 19.95 22.30 23.64 20.71 30.78 25.18 37.48
## CTNNA2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ELAVL1 95.29 84.38 73.85 89.55 75.18 94.68 76.54
## TIE1 0.61 0.43 0.52 0.60 0.23 0.53 0.33
## DIP2B 6.85 8.40 7.89 5.19 6.85 6.19 9.64
## SMARCD1 45.44 43.86 42.66 45.60 38.49 43.26 46.24
## KDM4A 13.92 16.75 17.76 10.63 12.99 13.77 16.63
## NFYC 44.52 42.90 42.72 42.14 39.22 44.42 53.55
## ZMYND12 1.73 1.28 1.73 0.77 0.98 0.65 1.40
## SLC9A3 0.17 0.21 0.24 0.14 0.08 0.09 0.06
## NGEF 15.83 17.20 17.64 10.30 8.90 12.69 12.90
## ASPM 16.93 24.19 19.73 14.48 10.66 17.70 11.09
## CD84 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ELOVL1 178.21 166.66 148.90 206.97 165.78 185.57 199.04
## SPI1 0.00 0.07 0.04 0.07 0.02 0.04 0.03
## ZNRD1 56.09 53.32 57.36 59.73 63.23 58.42 73.34
## MPPED2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CLDN18 0.01 0.02 0.00 0.00 0.00 0.00 0.00
## ZBTB11 9.12 9.20 9.67 5.77 7.06 7.66 8.82
## ATXN3 19.62 20.75 19.53 15.73 17.05 20.95 24.75
## GOLGA5 29.54 34.98 41.62 26.94 31.29 31.03 36.81
## FGFR2 0.06 0.07 0.09 0.00 0.02 0.33 0.13
## LRRC40 10.56 11.28 9.77 10.13 10.82 12.41 11.86
## ISOC1 13.80 13.44 10.71 14.22 10.73 15.38 12.62
## EML1 2.61 2.79 2.16 1.38 1.40 2.17 2.45
## TRMT11 12.83 12.34 11.37 10.51 9.03 11.21 8.72
## THUMPD1 17.07 16.59 14.13 12.62 12.19 14.61 15.56
## MSANTD3 85.66 75.51 70.70 90.97 77.02 96.44 78.90
## KIF26A 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ATG2B 3.21 4.55 4.52 2.93 4.51 3.07 7.36
## ARFGEF1 12.87 13.97 15.16 10.50 16.02 14.15 12.50
## ACSM2B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ZFAT 5.77 5.02 5.03 3.17 2.80 4.77 3.04
## MTFR1 20.64 19.37 17.06 19.60 24.20 22.64 25.58
## STAG3 0.59 0.60 0.85 0.31 0.29 0.59 0.28
## FECH 18.69 18.09 18.11 13.33 16.54 17.96 23.49
## MYO9A 3.32 4.85 4.06 2.64 4.16 3.28 5.29
## DDX3Y 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PFKP 187.44 175.52 171.76 177.39 162.15 195.86 183.62
## IDI1 58.64 49.20 58.25 64.88 70.68 71.32 98.99
## SP100 68.75 69.34 66.32 60.84 62.87 72.54 61.34
## KLF6 64.72 61.20 58.79 64.82 79.78 66.37 143.96
## PPAP2A 28.42 29.42 34.15 22.03 18.02 26.70 21.06
## NEO1 5.27 5.45 3.91 3.34 3.67 4.11 5.78
## TRAM1 130.29 114.41 122.14 100.14 116.84 131.22 140.70
## PHKA1 7.90 9.83 8.73 5.54 5.53 7.66 6.80
## TNFRSF1A 89.69 98.94 104.31 79.93 78.13 94.15 93.74
## CACNB1 4.72 4.74 3.69 5.73 4.37 3.43 9.11
## EVI5 22.38 25.99 22.96 14.53 21.48 21.07 24.31
## STOML1 9.64 9.54 8.35 11.51 8.80 12.12 9.06
## PKM 1658.35 1515.37 1513.05 1457.88 1261.15 1662.74 1343.37
## DHX29 26.94 27.22 24.48 21.48 21.44 28.84 27.01
## DNTTIP2 110.68 88.39 81.09 103.57 133.31 103.26 133.86
## METTL22 9.21 9.07 9.50 8.37 9.00 7.67 10.32
## TP53BP1 9.42 11.49 10.67 5.63 6.26 7.22 9.53
## TRO 0.01 0.00 0.02 0.01 0.02 0.00 0.02
## RRP15 38.91 30.80 25.63 38.50 38.30 41.66 44.40
## RHOA 541.09 546.26 526.72 541.79 541.84 581.27 506.86
## DHX8 26.55 28.90 26.85 23.49 22.65 24.75 31.61
## PRKCZ 13.69 12.91 12.56 12.96 9.33 13.84 13.14
## ZFY 0.00 0.00 0.00 0.03 0.00 0.00 0.00
## IARS2 88.34 97.30 94.59 72.33 80.76 91.65 77.27
## SYT1 0.95 0.95 0.68 1.03 0.34 1.57 0.40
## NAV3 12.14 8.59 7.75 17.30 23.64 13.81 26.77
## IDH3G 67.00 62.15 63.36 66.08 48.60 59.06 42.16
## ROGDI 6.15 6.60 6.84 4.81 4.29 6.60 6.25
## PDZD4 0.00 0.00 0.03 0.01 0.00 0.00 0.01
## ATP2B3 0.00 0.00 0.00 0.00 0.00 0.01 0.00
## ROCK1 22.01 23.71 21.65 19.29 24.67 21.54 28.66
## CBFB 37.01 35.74 31.80 31.33 37.79 38.37 52.87
## PDK3 5.76 5.45 6.11 4.88 4.39 5.77 6.33
## HYAL2 36.58 34.64 34.45 31.72 22.94 36.25 24.26
## HDAC4 3.37 3.69 2.98 2.26 3.10 2.81 2.82
## RASSF1 29.04 26.46 20.40 36.37 22.69 31.96 29.56
## FGFR3 1.52 1.64 1.41 1.23 0.75 1.44 1.20
## IFI35 49.83 48.85 61.07 32.46 33.18 36.80 33.28
## HEATR6 10.33 11.60 10.33 7.31 4.75 8.50 8.70
## COASY 67.59 67.75 70.63 56.08 36.24 57.71 39.72
## PLEKHH3 6.31 8.58 8.73 7.70 4.45 7.99 6.35
## MEF2A 18.60 23.60 28.31 11.37 16.96 16.55 20.87
## OTUD5 40.98 45.65 45.97 35.60 31.15 37.53 42.53
## TFE3 63.47 61.86 61.39 65.49 59.79 65.65 68.94
## TBC1D25 18.11 20.03 19.41 15.27 13.69 17.57 16.96
## ACSL4 58.05 59.06 49.61 55.57 58.08 62.78 71.11
## INPP5A 16.47 17.36 15.78 15.49 19.91 16.04 19.35
## GPKOW 28.71 30.21 31.60 25.03 18.76 25.63 20.81
## GRIPAP1 21.75 24.98 25.51 15.74 12.46 17.34 18.64
## FTSJ1 158.38 152.36 141.45 146.24 109.79 132.07 97.35
## PRR11 71.40 74.48 50.46 64.16 47.23 75.74 49.86
## REEP1 0.41 1.06 0.70 0.69 0.23 1.12 0.34
## ATP11A 10.07 11.21 11.25 6.84 8.22 8.72 10.39
## POLR1A 11.86 11.22 8.82 9.68 9.82 10.83 13.72
## LAPTM4A 175.92 169.01 182.11 152.57 156.32 182.37 177.21
## TTC7A 15.61 13.58 13.59 11.06 10.95 12.44 10.39
## IP6K2 54.77 58.11 61.33 43.13 47.55 39.57 57.12
## STON1-GTF2A1L 0.00 0.02 0.00 0.00 0.00 0.00 0.00
## SRBD1 6.43 6.98 6.25 7.28 6.83 7.94 7.95
## CYFIP1 36.79 36.63 35.93 34.46 27.37 35.71 29.48
## KIF2A 25.45 23.69 21.01 14.70 14.03 19.73 18.12
## RASGRP2 0.20 0.42 0.26 0.19 0.18 0.37 0.18
## PSME4 34.67 32.90 35.28 29.91 26.26 33.34 27.23
## IFT80 8.81 10.93 10.55 6.49 6.35 6.88 7.25
## SIRT2 36.11 37.49 34.56 39.61 35.61 39.94 48.26
## ERLEC1 58.07 67.58 76.48 45.10 45.81 55.30 49.20
## PPP2R5B 9.48 11.52 12.24 8.35 5.86 10.13 7.60
## PYGM 0.12 0.05 0.14 0.15 0.33 0.09 0.32
## PAGE1 0.00 0.04 0.04 0.13 0.10 0.07 0.05
## PITX1 39.04 42.23 46.06 33.98 22.14 37.19 25.26
## TRPC7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## MAST4 1.98 3.66 2.83 1.62 1.11 1.89 1.28
## GPR116 36.60 43.93 42.57 17.97 13.45 26.17 14.06
## SDK2 0.03 0.01 0.01 0.01 0.00 0.02 0.02
## ADAM7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NUP133 27.85 30.12 28.94 24.58 24.99 27.41 28.57
## NUCKS1 177.71 158.17 143.93 128.21 109.46 172.83 111.84
## VPS35 50.99 49.28 48.96 42.15 41.45 53.35 52.36
## DNAJA2 53.26 49.37 50.96 41.78 47.28 50.04 53.01
## BCL3 26.36 33.95 32.02 8.43 9.30 16.80 10.52
## KCNAB2 6.37 6.18 6.20 4.70 4.70 5.75 7.21
## ABCC9 0.04 0.09 0.04 0.11 0.12 0.14 0.20
## GAL 2.34 1.96 2.09 3.09 2.07 3.11 1.65
## CLEC2D 1.01 1.76 1.70 0.70 0.77 0.94 1.07
## FUNDC1 40.26 43.49 44.93 28.13 30.02 34.20 33.25
## MAOB 2.36 2.13 2.71 0.77 0.69 1.08 0.81
## RORA 0.30 0.22 0.39 0.24 0.35 0.30 1.04
## DRD4 0.28 0.18 0.23 0.24 0.34 0.21 0.17
## TGFBR3 4.41 6.21 7.05 4.48 6.46 6.15 9.31
## KIAA1107 1.26 1.92 1.96 0.78 1.11 1.25 1.55
## PLA2G10 0.03 0.00 0.00 0.00 0.03 0.00 0.00
## HES2 4.97 5.05 5.51 4.62 5.69 5.79 7.69
## ATP1B3 128.34 112.33 115.40 133.48 94.66 136.12 102.68
## NEDD4 8.32 8.55 7.25 7.76 8.51 9.63 10.91
## PIGB 9.67 10.25 9.55 7.15 5.54 7.91 5.94
## MAPK6 30.98 32.00 27.14 29.62 45.56 35.21 69.01
## GNB5 21.41 22.37 21.30 18.67 16.07 23.38 16.02
## RAB27A 30.64 30.94 31.68 18.88 18.69 24.64 23.04
## CECR5 25.51 22.37 19.92 27.19 26.18 26.97 31.85
## UFD1L 76.15 70.74 69.58 86.08 86.47 84.63 78.80
## LRP6 8.27 10.55 9.61 4.35 4.77 6.16 5.46
## GUCY2C 0.02 0.04 0.02 0.03 0.01 0.00 0.01
## SCT 0.00 0.00 0.09 0.11 0.12 0.00 0.00
## PHRF1 16.44 15.38 13.91 13.65 12.76 15.22 17.26
## IKBKAP 19.95 22.08 21.70 17.64 16.99 23.80 26.05
## NUCB2 162.07 159.14 176.99 121.95 100.37 153.23 79.95
## PFN2 28.60 24.01 24.21 24.47 29.14 30.27 33.90
## PTPN3 6.01 7.32 6.09 5.12 5.69 6.49 6.34
## SPTB 0.21 0.18 0.28 0.14 0.18 0.18 0.18
## DAPP1 0.09 0.18 0.20 0.10 0.09 0.12 0.20
## FGF10 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SLC44A1 17.03 18.27 21.09 10.74 11.88 14.65 13.99
## TMEM260 5.04 5.57 5.42 3.93 4.68 5.46 6.39
## SMG6 24.35 22.96 22.76 21.26 16.36 24.67 22.00
## EXOC5 37.34 39.88 34.31 24.59 31.86 35.11 43.15
## CLTCL1 3.11 2.26 2.68 2.58 2.42 2.46 2.05
## FGF22 0.42 0.50 0.21 0.28 0.21 0.36 0.40
## FSTL3 30.42 24.32 21.70 27.58 19.08 26.01 22.80
## DGCR2 20.22 19.85 19.69 18.82 17.64 21.70 21.68
## RNF126 64.93 52.29 52.25 61.33 44.14 60.27 44.66
## MNT 7.21 7.72 6.51 7.73 6.62 8.45 11.70
## ZXDC 7.04 7.62 8.09 7.07 6.84 7.39 10.98
## JMJD6 24.38 23.94 29.22 26.11 36.07 26.45 35.74
## POLB 21.52 18.46 21.03 15.32 13.83 17.31 14.26
## ST6GALNAC1 0.13 0.20 0.16 0.25 0.00 0.27 0.14
## WIPI1 38.76 39.89 48.35 49.00 53.44 43.86 72.44
## FRMPD1 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## GBA2 47.84 45.31 43.32 42.34 39.11 35.72 44.24
## NDST1 40.36 35.66 32.39 28.88 27.44 32.53 32.37
## ASNS 54.32 62.92 62.28 88.67 116.25 76.79 165.16
## AP3M2 21.93 18.64 17.45 19.10 15.99 21.14 15.65
## CNGB1 0.16 0.04 0.06 0.01 0.00 0.01 0.05
## ST6GALNAC2 8.63 8.97 10.63 5.35 3.55 7.20 4.22
## CHAT 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PABPC1 1245.40 1149.13 1058.25 1204.65 1175.34 1271.77 1552.94
## TESK2 2.51 3.37 4.02 1.99 2.32 2.98 2.66
## C16orf80 32.14 27.59 24.26 31.96 28.93 37.08 28.35
## CSNK2A2 31.97 32.39 29.49 31.28 35.98 32.87 47.54
## PTPN21 9.72 10.45 9.65 8.43 10.83 10.04 13.12
## EIF2B3 57.79 57.67 51.91 53.65 45.54 57.15 36.93
## CAMK2A 0.08 0.19 0.12 0.10 0.02 0.07 0.07
## TCOF1 35.88 28.65 21.39 34.74 22.16 34.09 28.18
## CDC42 391.42 388.35 377.63 400.20 415.70 428.80 424.92
## OSBPL3 33.69 32.70 31.04 26.43 26.03 33.33 31.09
## EPHA8 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## SLC12A3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RAD18 24.62 18.60 14.30 21.28 19.99 22.52 21.90
## ATP2B1 53.04 50.43 48.86 49.25 61.31 60.68 85.79
## TRPM5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NCK2 27.12 24.22 27.21 25.20 25.57 27.01 25.57
## MAP4K4 139.72 142.34 141.81 92.19 107.77 117.09 116.28
## MGAT4A 2.98 3.28 3.09 2.10 2.74 3.57 2.61
## RPL31 2203.50 2092.34 2323.11 2132.95 2410.26 2199.20 2222.48
## WDR1 581.54 587.90 506.21 510.12 435.55 562.12 413.01
## SNX13 11.52 12.63 11.81 8.32 12.26 11.72 15.41
## MS4A12 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ARHGAP10 13.79 11.41 9.32 14.46 11.87 14.69 14.45
## RPS6KA2 11.34 17.54 17.72 9.74 10.83 11.04 14.60
## ING3 18.84 15.65 12.69 14.94 12.70 15.70 14.84
## VASH1 1.45 1.48 1.85 0.65 0.42 0.87 1.21
## LMCD1 8.16 8.48 7.58 6.22 3.69 5.88 4.63
## WBSCR22 66.40 62.56 58.08 72.35 64.31 77.37 68.96
## SEL1L 29.73 34.29 36.49 22.28 30.45 28.72 45.75
## TRIP13 30.40 24.74 20.46 32.47 15.83 30.30 17.22
## ATP6AP1 92.80 91.78 89.91 86.69 73.42 96.91 98.55
## TCF3 44.32 42.80 40.16 47.36 36.56 46.59 38.65
## TRIB2 23.82 25.15 36.60 11.12 7.77 13.95 5.98
## DAZAP1 164.30 138.54 123.39 166.97 121.03 181.28 131.34
## MBD3 79.76 70.63 76.60 70.27 48.52 77.15 44.10
## PRLH 0.00 0.00 0.17 0.00 0.00 0.00 0.00
## HLTF 13.69 15.42 13.34 9.49 6.74 12.97 7.43
## FAM50A 149.97 143.34 141.19 166.04 135.55 162.00 160.47
## FAM3A 46.52 47.78 50.31 53.30 41.16 52.60 45.04
## CPSF1 67.56 62.46 65.62 63.73 41.79 54.39 59.30
## MYO3B 0.00 0.01 0.00 0.00 0.00 0.01 0.00
## CYBRD1 60.72 56.51 62.42 52.20 54.32 67.73 65.39
## CDH19 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PDCD2 109.71 92.09 94.53 109.80 92.72 120.26 88.24
## SLC6A15 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## RDH11 68.64 62.89 61.42 68.30 52.65 77.67 69.68
## PRKACA 64.69 70.29 61.82 54.27 38.47 59.57 40.96
## LPHN1 4.98 4.55 4.40 2.32 1.32 2.72 1.78
## SPP2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ACTN1 275.17 226.80 180.78 306.05 241.78 271.39 294.86
## ZFYVE26 4.03 4.95 4.70 4.29 4.69 5.66 7.87
## RPS6KA6 0.11 0.21 0.07 0.03 0.05 0.08 0.09
## EPN2 21.96 25.14 26.78 15.33 15.35 26.24 23.67
## PTPN18 23.59 20.61 17.74 25.29 17.94 23.78 28.03
## LIMS2 8.65 7.96 9.04 7.59 5.20 5.96 6.30
## ASIC4 0.04 0.02 0.15 0.05 0.04 0.08 0.15
## SPEG 8.39 8.85 9.29 6.02 3.36 6.92 4.55
## LNX1 2.23 2.28 3.08 1.16 1.14 1.94 1.61
## ALDH3A2 75.94 77.38 95.56 55.88 58.72 81.84 61.18
## TFRC 130.70 99.09 72.16 117.91 132.39 136.31 140.95
## SREBF1 89.81 81.08 95.18 61.55 29.09 68.11 40.84
## TRPC5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## AFF4 26.10 31.62 29.03 18.88 30.10 23.02 47.01
## UBE2D1 35.30 40.28 46.43 31.98 40.98 36.13 44.13
## MPP5 40.70 33.81 31.92 31.74 29.19 35.58 30.03
## RHOBTB1 4.47 3.48 3.13 2.68 2.69 4.08 4.15
## SMC1A 66.49 69.36 43.25 48.89 35.95 67.73 53.85
## HSD17B10 103.53 94.75 85.18 132.03 135.06 131.47 130.90
## MARK2 17.22 17.85 18.55 15.88 13.23 15.24 15.90
## HMMR 7.04 7.58 5.51 7.56 6.62 8.75 8.34
## CHFR 16.62 14.51 13.44 13.49 16.11 13.93 19.64
## TRHDE 0.01 0.09 0.01 0.01 0.01 0.01 0.00
## P4HA2 43.66 39.14 45.19 31.82 25.74 38.89 29.98
## FCGR2B 0.01 0.01 0.00 0.00 0.00 0.02 0.00
## NFATC3 5.66 6.99 6.02 3.94 5.01 5.68 6.78
## TRNT1 11.16 10.35 10.65 8.44 6.08 9.33 8.17
## ACADVL 213.13 228.56 272.45 177.93 178.16 151.90 189.43
## STK10 36.36 41.83 39.66 43.10 47.81 45.47 60.95
## FBXW11 30.17 34.88 38.09 21.50 28.80 28.60 33.34
## ACAP1 6.15 2.38 3.47 3.40 4.56 3.69 6.70
## CRMP1 3.76 3.91 3.46 3.41 3.10 4.26 4.34
## EVC 12.49 14.09 13.58 9.06 9.11 10.52 12.65
## DERL2 134.63 118.95 142.90 137.91 139.33 134.57 125.27
## SIDT1 0.13 0.21 0.16 0.09 0.10 0.12 0.18
## NDE1 28.41 28.70 24.93 22.35 21.54 23.67 21.66
## MRVI1 0.18 0.36 0.57 0.10 0.08 0.12 0.06
## TMEM38A 16.60 16.84 18.74 13.56 9.53 16.86 9.89
## AP1M1 95.65 86.04 77.59 100.86 70.99 98.22 75.62
## PVR 62.83 51.04 44.03 70.56 69.39 68.05 101.61
## IKBKG 42.91 38.67 41.73 44.90 48.98 45.75 61.94
## XRCC1 15.89 14.53 15.70 10.67 6.83 12.97 7.39
## SCARB1 27.18 22.76 21.23 24.72 20.02 28.70 24.60
## CYP2W1 0.01 0.12 0.07 0.04 0.09 0.09 0.13
## MCM2 37.74 28.50 17.45 38.35 27.91 39.97 35.82
## MOV10L1 0.04 0.06 0.04 0.05 0.04 0.00 0.15
## PANX2 4.07 4.22 5.78 3.85 4.80 4.04 4.01
## SELO 16.06 14.13 17.01 17.67 13.77 16.44 17.28
## TP63 0.21 0.39 0.46 0.07 0.04 0.28 0.10
## ALPK1 1.99 2.22 2.73 1.18 1.08 1.54 1.58
## LLGL2 13.38 11.49 15.18 9.58 5.80 11.48 7.12
## PDE8A 14.77 15.53 15.71 10.64 12.42 12.83 13.21
## CLCN4 15.63 13.98 13.23 10.93 8.26 12.42 9.64
## NLE1 21.95 17.94 13.82 23.19 16.46 22.64 21.83
## SDHA 151.29 170.32 191.36 119.70 82.55 131.76 77.47
## SMARCE1 159.96 147.87 134.52 138.79 140.46 155.79 163.38
## FNDC8 0.09 0.04 0.04 0.00 0.02 0.14 0.18
## GSDMB 1.29 1.73 1.91 0.82 0.88 0.72 0.89
## KDM5A 6.46 8.32 7.67 3.90 6.54 5.36 9.07
## ADAM11 0.30 0.36 0.41 0.20 0.14 0.29 0.51
## PPP2R3A 6.29 6.32 5.22 5.47 4.95 6.11 6.00
## FERMT2 37.33 35.60 34.20 34.31 41.63 39.99 52.37
## ABCB11 0.01 0.01 0.00 0.00 0.00 0.00 0.00
## DHRS9 0.43 0.51 0.53 0.17 0.08 0.11 0.43
## CD5L 0.00 0.01 0.04 0.00 0.01 0.00 0.03
## PTGS2 2.59 4.46 3.25 1.63 1.14 1.50 1.94
## IGF2BP2 37.04 32.27 28.69 39.07 24.90 37.74 30.66
## MAP3K13 32.34 30.18 29.03 29.05 29.28 30.15 31.59
## ST6GAL1 0.95 0.86 1.11 0.37 0.34 0.65 0.36
## TBX21 0.00 0.00 0.00 0.00 0.01 0.02 0.00
## FRY 0.40 0.37 0.37 0.09 0.18 0.24 0.06
## PICALM 189.11 182.03 160.42 179.64 184.87 190.07 224.59
## NSF 24.72 26.22 23.62 19.23 24.09 25.74 28.36
## GLI2 2.19 1.73 1.94 0.81 0.51 1.89 0.31
## CLASP1 9.07 10.34 9.96 6.80 6.84 7.88 8.61
## MRPS34 105.79 93.13 94.13 105.33 67.01 104.42 57.10
## NOTCH3 0.15 0.28 0.30 0.16 0.11 0.07 0.08
## CLNS1A 126.79 115.36 108.21 111.10 91.56 133.38 86.17
## PPP2R2C 2.11 2.98 2.67 1.63 1.40 2.18 1.25
## TEAD2 18.78 16.57 17.35 16.26 12.79 16.36 10.12
## EED 30.89 27.91 25.03 27.35 25.85 30.22 24.53
## CDHR2 0.07 0.15 0.08 0.05 0.01 0.01 0.01
## SNCB 0.00 0.00 0.02 0.00 0.00 0.00 0.03
## TSG101 141.62 143.86 147.32 121.04 117.61 133.78 133.16
## C17orf85 21.58 19.84 17.94 16.69 19.80 19.11 25.28
## ATP2A3 0.17 0.17 0.25 0.06 0.05 0.20 0.10
## CA12 31.35 26.37 30.92 10.90 7.79 19.37 7.87
## MGLL 19.93 18.44 14.76 21.56 14.90 21.87 21.04
## NTN4 12.30 18.50 16.84 11.69 12.47 14.43 15.64
## BCS1L 35.39 33.00 28.76 43.90 37.10 36.96 43.21
## NUAK1 13.02 9.87 10.82 7.35 5.62 7.75 6.88
## DPP8 13.19 15.39 14.63 9.95 10.35 12.99 10.68
## SLC24A1 4.00 5.14 5.35 3.57 4.23 2.88 6.92
## ZNF532 9.80 10.34 10.85 6.22 7.27 6.12 13.60
## SCARF1 0.95 1.18 1.37 0.79 0.57 0.66 1.04
## LMAN1 63.72 70.06 72.61 48.58 49.26 62.88 50.73
## PTPLAD1 63.16 56.50 52.09 50.50 41.30 61.58 49.51
## IPCEF1 0.13 0.09 0.09 0.03 0.04 0.08 0.12
## ZZEF1 5.39 7.27 6.14 4.73 5.46 5.07 7.82
## NOX3 0.00 0.00 0.02 0.00 0.01 0.00 0.00
## ENO1 2850.84 2676.04 2680.53 2953.13 2502.19 3068.88 2618.91
## SLC12A1 0.00 0.01 0.04 0.00 0.00 0.00 0.00
## C19orf10 300.91 279.86 336.42 318.29 276.00 324.54 238.77
## ANO8 6.86 7.70 8.32 4.44 3.22 4.87 3.69
## TUBE1 4.71 5.23 4.72 4.95 10.60 6.43 10.26
## ARHGEF10L 6.36 6.17 7.05 5.83 6.21 6.39 8.74
## TXK 1.67 2.45 3.22 1.02 1.20 1.77 1.06
## WSCD2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## KCNQ2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TACR2 0.14 0.12 0.18 0.08 0.17 0.02 0.30
## ACTR6 26.59 30.17 32.20 24.18 32.95 29.55 35.30
## TIPIN 30.93 19.75 13.37 32.23 25.37 31.92 26.18
## SRI 198.50 188.67 183.75 185.92 166.78 206.86 172.78
## EIF4G3 28.43 29.66 28.15 19.54 14.33 24.50 16.63
## NUP37 46.91 45.91 37.08 47.71 41.72 51.69 43.45
## SEMA3A 6.34 7.88 4.44 4.64 2.80 6.38 3.96
## GTSE1 21.97 24.36 18.92 20.23 11.49 22.42 12.21
## SEMA3C 32.48 27.07 28.41 14.52 10.05 18.92 11.25
## TTC38 33.60 33.67 32.51 31.36 28.88 35.66 34.39
## ACAT1 107.75 107.97 104.80 98.28 99.56 122.69 109.42
## GRAMD4 11.53 8.24 9.70 6.20 6.15 9.00 11.03
## CELSR1 3.94 4.06 4.78 2.66 2.96 4.15 3.48
## WNT8B 0.09 0.07 0.05 0.02 0.03 0.02 0.15
## ZNF638 30.26 34.27 39.89 25.43 26.40 34.85 32.12
## SLC25A40 10.91 11.00 9.34 9.59 8.22 11.64 12.28
## TIMM21 28.63 22.18 18.22 25.79 22.89 27.68 26.13
## ADD2 0.02 0.02 0.09 0.07 0.01 0.20 0.18
## FGF4 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RASAL2 11.54 11.43 8.90 11.59 12.49 11.62 22.10
## VPS9D1 4.20 4.92 7.13 4.22 2.71 3.03 4.05
## ZNF37A 6.57 6.90 6.77 5.03 5.91 6.56 8.70
## MARK3 50.93 48.34 50.17 43.68 49.25 50.66 58.65
## SLC25A3 692.34 657.96 626.91 671.87 617.90 687.54 612.04
## FNDC3B 25.58 24.45 26.89 18.66 23.03 19.68 29.39
## FOSL2 37.10 50.46 43.62 33.93 42.09 45.32 63.57
## CACNG5 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CACNG4 0.14 0.04 0.14 0.06 0.02 0.06 0.01
## FRYL 13.76 16.04 14.11 11.70 12.14 14.07 14.67
## TMEM131 33.68 31.99 27.96 22.35 23.54 28.87 27.62
## FSCN1 27.21 23.72 24.71 18.61 14.66 19.55 14.42
## ACTB 4372.33 3938.45 3633.10 4572.48 3318.91 4126.98 3107.22
## MOCOS 8.95 9.63 9.95 10.01 12.67 11.16 16.77
## PLD1 10.55 10.11 13.23 7.28 4.89 6.89 6.70
## ATP12A 0.01 0.00 0.00 0.00 0.00 0.00 0.00
## WDR62 15.97 15.03 9.65 18.89 11.40 17.27 14.21
## DLG1 93.52 109.31 106.44 65.31 65.52 77.38 80.13
## RAB7A 174.87 167.05 167.88 185.18 213.13 208.01 292.02
## BCAP29 62.10 62.83 54.28 62.14 61.68 69.52 56.44
## SEC31B 5.30 6.45 6.62 4.51 2.92 3.24 3.80
## SART3 29.56 27.06 23.75 20.90 21.52 24.72 29.33
## ARHGAP15 0.00 0.05 0.03 0.03 0.00 0.05 0.06
## TUBA3D 0.12 0.09 0.08 0.08 0.12 0.03 0.16
## PAX2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## EXOSC7 50.93 42.56 46.08 47.33 41.27 51.26 47.61
## KIFAP3 15.01 17.85 16.41 13.93 15.10 15.81 19.01
## MKRN2 29.76 28.03 25.05 30.00 29.28 29.94 33.79
## MCM6 49.04 34.20 22.47 43.26 28.51 45.88 30.81
## REXO2 162.40 156.43 172.70 165.31 146.68 167.64 145.90
## RBM7 37.92 39.53 39.89 25.44 34.70 34.06 43.36
## RBMS2 11.19 11.69 9.12 10.90 9.36 11.04 11.65
## BAZ2A 16.59 21.20 20.22 11.27 13.08 13.89 18.43
## PTPN23 24.17 23.19 20.34 23.84 19.43 25.17 30.29
## MLH1 33.74 30.13 24.43 32.32 32.85 33.87 41.31
## UNG 83.96 54.10 39.45 68.93 40.21 74.94 29.61
## FMO4 0.62 0.60 0.91 0.77 0.31 0.58 0.93
## KLHL20 10.95 13.08 11.81 7.53 9.86 11.06 12.07
## RGS11 0.04 0.01 0.03 0.01 0.01 0.00 0.00
## SLC46A1 7.65 6.09 6.03 4.33 3.58 6.50 5.32
## PLXNA2 4.15 3.77 3.38 3.45 2.42 3.95 2.73
## SPAG5 39.72 44.37 34.55 37.23 19.82 40.89 22.99
## ANKRD13A 37.94 36.20 29.01 36.33 19.84 39.45 27.14
## TPD52 62.49 57.45 48.44 58.57 62.01 61.57 75.19
## ACACB 1.19 2.40 1.24 0.82 0.92 1.06 0.74
## TRAF4 38.28 33.45 30.15 41.76 38.45 39.26 58.64
## PAG1 7.05 9.04 6.50 6.64 8.49 9.13 12.68
## GPATCH1 6.13 6.82 7.53 5.35 4.99 7.08 5.98
## ICAM3 12.16 12.05 11.85 12.97 13.63 14.36 12.56
## NT5C2 103.31 84.70 86.26 95.77 112.44 107.34 142.24
## MCAM 14.86 15.26 12.52 13.15 6.71 14.16 9.43
## GPC4 0.10 0.08 0.09 0.03 0.04 0.02 0.11
## MBNL3 1.66 1.88 1.33 1.28 1.40 1.61 2.24
## CAMSAP3 0.77 1.14 1.30 0.67 0.82 0.74 1.82
## RAP1GAP 3.25 3.72 4.39 2.55 4.71 4.38 6.66
## XAB2 32.66 35.10 34.40 32.74 29.03 32.52 37.55
## ARHGEF1 73.64 64.31 61.95 75.78 44.61 68.11 49.13
## STXBP2 88.82 92.34 95.54 73.16 68.19 72.08 84.70
## MAP2K7 22.93 24.72 25.17 21.43 18.00 23.19 23.12
## NMRK2 0.00 0.00 0.00 0.03 0.00 0.00 0.00
## DGKD 24.47 29.48 28.59 26.91 34.63 18.60 46.66
## CTTNBP2 0.07 0.00 0.00 0.00 0.00 0.00 0.00
## ACTL6B 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RARB 0.12 0.11 0.20 0.06 0.10 0.09 0.13
## TOP2B 50.82 63.47 65.49 44.39 49.68 53.65 55.47
## TM9SF3 100.13 116.34 107.62 80.76 96.89 101.00 97.92
## NFKB2 63.18 67.19 72.80 50.03 60.22 43.92 63.42
## UBE2T 124.28 116.24 91.28 130.78 84.95 130.38 68.31
## PPP1R12B 1.55 2.46 2.43 1.67 1.00 1.79 2.01
## DNAJC10 40.63 40.41 38.78 33.42 33.52 39.89 38.85
## GTF3C1 28.34 29.06 29.92 26.57 22.94 26.63 25.24
## IL4R 21.49 21.67 19.00 16.77 14.79 18.14 18.31
## USP33 29.74 32.73 33.71 25.27 28.86 31.15 36.25
## PAK3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CAPN6 0.00 0.00 0.01 0.01 0.00 0.00 0.00
## DCX 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SNRPA 81.06 68.34 66.37 80.34 45.98 73.72 43.02
## SPAG6 0.00 0.02 0.05 0.03 0.09 0.00 0.12
## EXOSC5 35.59 32.26 29.19 44.59 31.46 43.37 35.87
## DYNC1I2 76.81 77.33 75.04 59.95 51.98 73.59 62.82
## APBB1IP 10.98 11.35 9.54 13.02 7.78 13.27 12.17
## LRCH4 34.44 36.07 39.51 35.01 26.14 31.50 33.82
## FAM76B 22.27 20.63 18.25 16.00 20.38 20.57 25.27
## SIRT6 27.00 26.52 29.57 38.97 42.08 30.75 52.78
## TYR 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## POLD3 22.86 18.93 14.11 19.22 13.99 21.38 15.16
## ACTN2 0.04 0.03 0.10 0.00 0.00 0.00 0.00
## CAPZB 249.05 237.42 240.48 249.95 220.92 256.63 217.63
## GPR137B 7.19 7.62 7.31 7.71 11.64 8.48 14.00
## NAALAD2 0.18 0.08 0.06 0.11 0.10 0.03 0.07
## JADE1 17.57 18.55 15.49 14.79 9.90 16.09 13.63
## SLC25A43 20.01 19.22 20.33 16.85 14.46 19.33 13.21
## UBE2A 130.42 134.55 123.54 122.39 146.31 148.89 154.41
## FGFR1 67.56 64.66 57.63 65.41 55.91 67.32 74.64
## FKBP6 0.00 0.04 0.05 0.07 0.17 0.00 0.04
## GTF2I 102.73 115.86 128.08 66.06 61.33 83.94 59.30
## SMC1B 0.06 0.05 0.01 0.01 0.02 0.02 0.01
## FBLN1 1.22 1.46 1.25 0.71 0.37 1.20 0.53
## ITGA8 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## CST7 18.66 15.95 21.67 16.12 14.71 18.03 11.31
## MAP2 1.26 1.14 1.24 1.32 4.10 1.34 6.36
## PIAS2 8.09 7.94 7.70 7.51 6.57 7.97 7.36
## AMPH 0.08 0.01 0.07 0.03 0.00 0.14 0.00
## ARAF 73.97 81.88 82.13 64.46 45.97 65.36 52.73
## MCCC1 26.74 25.60 26.27 23.42 22.50 25.81 28.39
## LAMP3 2.41 2.61 2.44 2.24 2.87 2.44 4.23
## FAP 0.10 0.13 0.13 0.06 0.14 0.06 0.25
## NEBL 1.34 1.02 1.12 0.63 1.46 0.87 2.28
## ACER3 15.57 16.78 14.09 13.75 16.05 15.21 20.66
## UBE2K 94.38 86.13 88.65 85.34 98.52 96.24 130.32
## PIK3C3 63.51 74.09 81.15 58.11 69.00 65.72 89.71
## N4BP2 1.93 2.53 1.91 1.48 1.63 2.06 2.54
## C12orf5 13.72 12.14 12.37 11.56 11.71 14.53 12.33
## TULP3 18.05 19.69 18.29 17.46 19.65 20.92 23.02
## SYNJ2 44.63 46.88 50.43 35.74 34.74 37.74 23.88
## ADCY2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PPP2R5C 106.74 106.74 102.71 86.83 84.96 110.68 82.07
## RBFOX1 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## GNB1 350.70 332.85 314.33 302.90 310.41 331.21 339.34
## HOXA9 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## EDN1 9.08 5.43 4.17 8.31 4.79 7.23 4.89
## MLLT10 11.98 16.51 15.41 12.96 14.87 16.52 22.35
## ZCWPW1 5.11 6.13 6.21 5.03 5.50 4.61 6.96
## ADCYAP1R1 0.00 0.00 0.01 0.00 0.02 0.00 0.02
## FGF20 0.10 0.01 0.13 0.01 0.03 0.05 0.09
## P2RY10 0.00 0.03 0.00 0.00 0.00 0.06 0.00
## ITM2A 0.00 0.03 0.00 0.00 0.00 0.00 0.00
## NRD1 120.83 118.06 115.98 114.56 99.55 127.04 110.00
## VDAC3 123.20 129.31 112.32 125.66 119.57 139.11 113.02
## PCM1 43.59 49.21 43.98 39.04 47.35 44.05 55.32
## TNRC6C 2.31 3.53 2.47 1.74 2.33 2.32 3.72
## CBFA2T2 5.35 6.85 6.96 5.07 6.29 5.19 9.54
## BRINP1 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## ITCH 34.06 37.00 35.34 24.00 29.32 29.38 42.95
## PKD2L2 0.00 0.01 0.01 0.00 0.00 0.00 0.02
## TP53INP2 16.27 16.88 18.72 12.09 12.26 13.51 17.49
## SDF4 163.22 161.05 160.12 158.55 142.05 171.34 156.93
## MYH7B 0.17 0.05 0.07 0.02 0.04 0.02 0.14
## BPIFB2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## TP73 2.73 2.24 1.41 2.41 0.72 2.74 0.52
## TOLLIP 45.70 43.90 43.29 45.81 56.06 55.31 68.72
## UBE2D4 16.04 13.90 13.52 18.22 15.01 18.20 19.37
## CLUL1 0.03 0.11 0.30 0.19 0.00 0.09 0.45
## RUNX1T1 0.02 0.03 0.05 0.00 0.00 0.02 0.00
## CDH17 0.08 0.16 0.17 0.03 0.06 0.07 0.04
## THOC1 31.54 29.03 26.72 26.89 22.21 27.55 25.87
## FKBP7 14.51 13.95 18.04 10.73 8.71 13.29 8.96
## OSBPL6 5.47 4.24 3.36 5.71 4.31 5.77 5.59
## SLC1A3 11.03 6.02 8.94 3.93 2.57 4.32 2.71
## XRCC5 179.04 167.17 136.19 152.41 127.37 179.94 140.51
## LXN 17.11 18.81 19.19 11.26 13.48 16.48 14.72
## SP140 2.87 2.32 2.41 2.24 1.71 2.92 2.09
## MKNK1 28.01 33.66 30.89 28.68 23.62 30.50 26.72
## TNS1 0.19 0.37 0.35 0.20 0.09 0.12 0.14
## REXO1 20.20 19.30 17.24 20.04 20.36 19.60 25.97
## SAR1A 79.68 75.77 78.96 66.28 73.52 77.48 91.23
## CDC14A 2.88 2.91 2.79 2.00 2.19 2.56 2.47
## RAPGEF3 2.16 2.30 2.25 2.36 0.95 1.80 1.48
## CEACAM1 0.20 0.11 0.37 0.11 0.35 0.16 0.57
## SENP1 10.91 10.47 9.41 9.38 10.43 9.44 11.24
## DUSP13 0.20 0.06 0.20 0.06 0.11 0.11 0.13
## CIC 23.71 28.28 26.49 19.84 17.66 23.26 23.89
## LIPE 5.54 5.95 4.84 5.77 3.88 6.14 4.81
## FDFT1 80.47 74.14 78.39 109.56 83.00 110.39 125.15
## PAFAH1B3 57.66 48.01 49.22 62.90 33.01 59.29 40.51
## OPHN1 8.91 8.34 6.88 7.10 7.23 10.21 9.52
## AFM 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## KIF22 54.29 57.05 50.70 61.06 46.85 57.69 52.33
## SCGN 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## LRRC16A 3.47 4.47 4.90 3.31 1.96 3.82 2.61
## PGM1 79.65 76.78 78.74 60.95 44.87 73.26 44.95
## DDX1 70.94 70.15 65.90 58.60 51.72 72.66 56.44
## DNM2 136.71 148.74 144.86 140.72 109.20 132.09 124.72
## EPB41L2 36.15 39.46 28.75 41.47 31.15 37.98 38.52
## RIMS1 0.11 0.11 0.08 0.09 0.07 0.06 0.19
## MOXD1 2.91 3.10 2.31 2.73 2.80 3.21 3.30
## STX7 28.07 28.05 27.37 23.40 23.19 28.90 31.52
## RABL2B 11.02 11.51 11.09 8.66 6.86 7.46 10.00
## KEAP1 79.75 78.99 78.67 86.87 93.45 86.00 87.46
## DDX43 0.01 0.02 0.02 0.02 0.03 0.07 0.00
## PTPRH 2.67 4.34 3.67 2.15 2.23 2.69 4.01
## DCT 0.00 0.05 0.00 0.01 0.02 0.04 0.07
## SLC35C2 54.15 53.53 53.78 50.93 36.71 46.91 45.21
## CRYBG3 10.78 10.37 11.10 11.08 13.09 11.96 15.78
## EPHA6 0.00 0.00 0.02 0.00 0.03 0.00 0.00
## SCTR 0.00 0.00 0.00 0.01 0.00 0.00 0.15
## RFX3 0.57 0.92 0.61 0.50 0.39 0.59 0.47
## RIF1 10.53 9.48 7.90 7.09 8.28 9.13 11.30
## RAB21 47.84 49.31 40.49 45.21 51.40 50.57 68.42
## SLC4A4 1.05 1.76 1.05 0.78 0.67 1.09 0.72
## SMARCA2 29.80 36.46 33.76 24.64 24.66 28.48 37.27
## RDH8 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SESN1 3.22 3.78 3.27 2.89 3.40 3.39 4.49
## MID2 4.28 4.74 5.03 3.47 3.91 3.50 7.36
## PIH1D3 0.00 0.04 0.02 0.00 0.03 0.00 0.00
## COL5A3 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## SRCAP 13.35 15.75 13.74 11.33 12.27 11.99 16.28
## KIAA0020 90.25 64.56 55.19 81.82 76.44 82.39 80.58
## CPB2 0.02 0.05 0.00 0.03 0.00 0.00 0.00
## CHRNA3 0.03 0.04 0.08 0.07 0.08 0.02 0.03
## KCNN2 0.05 0.02 0.04 0.04 0.02 0.13 0.10
## CNOT4 10.16 10.34 10.27 9.18 12.37 11.45 16.11
## PSEN1 34.62 39.00 38.65 35.90 47.85 39.20 63.44
## CPOX 106.93 128.36 138.98 64.55 60.75 94.35 54.78
## CLDND1 319.59 391.92 413.43 221.95 179.87 259.05 172.03
## MOK 47.56 39.20 32.78 43.65 40.71 38.98 34.44
## HSP90AA1 941.01 807.62 669.79 870.14 866.37 1039.96 769.39
## RBL1 19.86 16.08 9.73 17.78 14.11 21.42 15.31
## DLGAP4 67.09 75.22 74.17 60.18 47.31 62.82 54.21
## IGSF9B 0.13 0.02 0.01 0.11 0.06 0.02 0.01
## CFHR2 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## NDC80 50.95 56.39 40.93 48.03 27.88 55.09 27.21
## AP4E1 4.29 4.54 4.03 3.05 3.91 4.13 5.63
## RSBN1 6.09 5.81 5.82 4.14 4.21 6.60 7.97
## MAGI3 4.42 4.94 3.98 3.64 2.59 4.38 3.34
## CXCL2 5.01 5.16 5.34 3.54 4.48 2.77 9.11
## AFP 0.35 0.16 0.25 1.03 1.49 1.11 2.20
## COL4A4 0.08 0.08 0.10 0.11 0.10 0.09 0.13
## TCF7 2.60 2.86 2.22 2.70 2.01 2.72 2.49
## OSTM1 17.95 14.35 13.20 15.69 20.83 21.45 24.45
## CDH7 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## IMPG2 0.02 0.01 0.02 0.02 0.02 0.03 0.02
## PCNP 170.86 167.40 155.02 148.72 159.20 187.13 160.80
## EXD2 7.35 8.07 8.40 7.61 8.45 8.39 11.33
## ARG2 4.55 4.29 5.03 3.59 1.96 5.23 3.02
## MEF2C 8.93 9.61 10.41 3.68 2.92 5.95 3.47
## PTPRC 0.03 0.07 0.05 0.02 0.05 0.02 0.08
## CACNA1S 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## PKP1 0.01 0.04 0.00 0.00 0.00 0.01 0.07
## UBA5 19.65 19.22 18.27 14.93 18.31 18.53 22.24
## STK17B 22.26 26.86 23.75 14.89 21.91 19.76 25.95
## CDC14B 11.24 13.97 14.78 10.23 10.85 12.01 13.32
## ZNF510 4.73 5.29 4.60 3.36 3.35 3.78 4.84
## LRP2 0.07 0.02 0.01 0.02 0.01 0.01 0.07
## ZNF506 10.76 10.38 9.59 7.44 7.13 8.20 9.51
## JMJD4 17.44 14.66 16.61 15.94 10.13 14.53 13.32
## DUSP12 48.42 43.73 44.97 45.67 44.31 45.00 45.91
## AACS 14.49 13.31 12.64 12.49 9.69 14.07 12.12
## KIAA0141 41.60 39.26 37.01 35.17 22.22 31.75 24.77
## SLC13A1 0.00 0.00 0.01 0.00 0.00 0.00 0.00
## CADPS2 6.96 8.14 8.79 4.47 2.68 6.25 2.50
## PCDHB4 0.05 0.06 0.06 0.02 0.01 0.04 0.03
## PCDHA6 0.02 0.00 0.00 0.00 0.00 0.00 0.01
## PCDHGA2 0.20 0.33 0.34 0.13 0.13 0.24 0.28
## HSPB11 125.62 120.02 112.93 134.81 142.91 147.15 132.74
## PHLPP1 3.68 3.84 3.06 3.71 2.47 3.79 3.13
## ATP8B1 8.75 7.31 6.32 9.52 7.52 9.44 11.35
## IL12RB2 0.01 0.01 0.00 0.04 0.11 0.02 0.07
## SMARCD3 16.83 17.81 20.10 12.79 12.53 14.44 15.85
## WDR70 25.89 19.75 21.63 21.44 17.60 25.69 21.85
## FYB 0.09 0.04 0.06 0.04 0.04 0.09 0.07
## MPP4 0.68 0.65 0.36 0.65 0.20 0.76 0.20
## STRADB 44.06 41.33 45.72 38.57 37.36 42.34 38.86
## BZW1 305.96 276.72 235.20 279.22 316.28 313.21 356.32
## PGR 0.00 0.02 0.01 0.00 0.00 0.00 0.01
## C1QTNF3 1.00 1.48 1.76 0.78 0.60 0.94 0.48
## ME2 27.11 23.55 22.41 21.35 22.01 27.71 26.23
## C5orf22 30.03 27.91 24.10 28.02 28.19 32.69 36.33
## CCNT2 8.39 7.83 7.32 5.69 8.07 6.51 11.96
## FAM135A 3.49 3.42 4.33 3.08 3.34 3.11 3.86
## COL19A1 0.00 0.00 0.00 0.00 0.00 0.00 0.01
## EPB41L3 0.25 0.08 0.14 0.13 0.07 0.09 0.19
## COBLL1 2.67 1.74 1.42 2.83 2.79 3.25 4.23
## DLG3 12.27 13.72 12.34 7.20 4.66 10.10 5.57
## KCNK2 0.40 0.48 0.34 0.21 0.24 0.18 0.17
## SERTAD4 8.53 5.51 4.75 6.51 2.82 5.95 3.22
## TRAF5 8.12 8.45 7.72 6.74 5.34 7.86 7.96
## MRPL22 74.97 72.74 67.51 74.01 73.87 82.23 67.60
## GEMIN5 15.01 12.12 9.97 12.32 11.65 12.53 14.46
## OPRK1 0.01 0.01 0.01 0.01 0.00 0.00 0.00
## NFE2L1 141.81 147.59 128.01 115.72 116.83 131.82 202.49
## SEMA5B 0.11 0.02 0.01 0.04 0.06 0.03 0.15
## GSK3B 16.89 16.45 16.58 15.91 10.66 14.39 12.68
## ITGB5 144.13 122.78 138.41 96.42 84.88 115.55 83.42
## ERC1 5.74 6.85 5.29 4.94 4.52 5.90 7.58
## XPO1 81.23 82.23 67.63 67.46 72.22 83.48 80.58
## C4orf6 0.00 0.00 0.00 0.00 0.00 0.00 0.00
## RNF13 20.03 22.77 23.11 17.13 19.78 25.45 24.87
## TRPM3 0.20 0.46 0.47 0.37 0.01 0.19 0.24
## PALB2 9.88 8.62 9.04 10.68 9.73 11.42 10.92
## DOPEY1 1.61 1.94 1.81 1.03 1.22 1.30 2.00
## LYRM2 45.53 45.33 44.71 36.35 34.40 43.83 38.67
## BCKDHB 8.08 7.83 8.02 6.22 5.38 7.41 4.32
## [ reached getOption("max.print") -- omitted 17095 rows ]The motility data frame
The object cell_speeds_df contains data that is completely new to us.
# Check out this new table Get the column names of this data frame:
# Replace FUNCTION with a function that extracts the column names
colnames(cell_speeds_df)## [1] "sample" "cellLine"
## [3] "diagnosis" "experimentalCondition"
## [5] "summary_metric" "average_value"
## [7] "total_number_of_cells_tracked"A little background!
- sample is the name of the experiment
- cellLine is the human cancer cell line name
- diagnosis is the cancer type that the cell line models
- experimentalCondition is the substrate on which the cells were grown
- summary_metric has cell speed in microns per hour
- average_value is the average cell speed
- total_number_of_cells_tracked how many cells were watched in the imaging microscope
Cancer cell lines
What cell lines (cellLine) were examined?
And what cancer types do the cell lines represent (diagnosis)?
We can use the function unique() on the table to get the information for both features.
# for cell lines and the cancers they model
unique(cell_speeds_df[,c(2,3)])## cellLine diagnosis
## 1 SW620 Colon Cancer
## 8 SW480 Colon Cancer
## 14 RWPE-1 Not Applicable
## 21 A375 Skin Cancer
## 28 T98G Brain Cancer
## 35 22Rv1 Prostate Cancer
## 42 T-47D Breast Cancer
## 49 U-87 Brain Cancer
## 56 MDA-MB-231 Breast CancerWe are interested in the two breast cancer cell lines:
- T47-D
- MDA-MB-231
Experimental conditions
Each experiment was conducted under different conditions. The column “experimentalCondition” gives the type of substrate on which cell speed was measured.
# Replace FEATURE with the column name to get the experimental conditions
table(cell_speeds_df$cellLine)##
## 22Rv1 A375 MDA-MB-231 RWPE-1 SW480 SW620 T-47D
## 7 7 7 7 6 7 7
## T98G U-87
## 7 7We will use the data for the experimental condition HyaluronicAcid Collagen.
Hyaluronic acid and collagen
Hyaluronic acid, collagen, and fibronectin are all common components of the extracellular matrix for biological cells. The extracellular matrix is a complex network of proteins and other molecules that
- surrounds and supports cells,
- influences cell behavior, and
- facilitates communication between cells.
It is a biologically meaningful material on which to measure the movement of cells!
substr_img<-load.image("/home/data/substrate.jpg")
plot(substr_img,axes=FALSE)
Hyaluronic acid is a type of sugar molecule that maintains tissue structure. Hyaluronic acid’s unique properties, such as its ability to bind water and interact with other components of the extracellular matrix, contribute to its diverse functions in the body.
Let’s look in more detail at the condition HyaluronicAcid Collagen.
# Make a smaller data frame for this condition with a new function `subset()`
hyal_coll_df <- subset(cell_speeds_df,
experimentalCondition == "HyaluronicAcid Collagen")
hyal_coll_df## sample cellLine diagnosis experimentalCondition summary_metric
## 2 mRNA_R21 SW620 Colon Cancer HyaluronicAcid Collagen speed_um_hr
## 8 mRNA_R42 SW480 Colon Cancer HyaluronicAcid Collagen speed_um_hr
## 15 mRNA_R28 RWPE-1 Not Applicable HyaluronicAcid Collagen speed_um_hr
## 22 mRNA_R49 A375 Skin Cancer HyaluronicAcid Collagen speed_um_hr
## 29 mRNA_R14 T98G Brain Cancer HyaluronicAcid Collagen speed_um_hr
## 36 mRNA_R7 22Rv1 Prostate Cancer HyaluronicAcid Collagen speed_um_hr
## 43 mRNA_R56 T-47D Breast Cancer HyaluronicAcid Collagen speed_um_hr
## 50 mRNA_R35 U-87 Brain Cancer HyaluronicAcid Collagen speed_um_hr
## 57 mRNA_R63 MDA-MB-231 Breast Cancer HyaluronicAcid Collagen speed_um_hr
## average_value total_number_of_cells_tracked
## 2 18.477557 51
## 8 8.814832 40
## 15 13.225218 108
## 22 43.955352 52
## 29 31.561848 75
## 36 19.510723 50
## 43 16.515478 81
## 50 39.380265 58
## 57 36.196133 12Nine experiments were done on the “HyaluronicAcid Collagen” substrate.
Two of the experiments were done with the breast cancer cell lines we are interested in, i.e. T-47D and MDA-MB-231.
# Make an even smaller data frame that includes only the breast cancer cell lines
# Replace CANCER TYPE with the `diagnosis` we're interested in
hyal_brca_df <- subset(hyal_coll_df,
diagnosis == "Breast Cancer")
print(hyal_brca_df)## sample cellLine diagnosis experimentalCondition summary_metric
## 43 mRNA_R56 T-47D Breast Cancer HyaluronicAcid Collagen speed_um_hr
## 57 mRNA_R63 MDA-MB-231 Breast Cancer HyaluronicAcid Collagen speed_um_hr
## average_value total_number_of_cells_tracked
## 43 16.51548 81
## 57 36.19613 12The summary_metric is cell speed in microns per hour. From this table, we see that one cell line (MDA-MB-231) moves twice as fast as the other cell line (T-47D) on the “HyaluronicAcid Collagen” substrate: 36 u/hr versus 16 u/hr.
# Get speed information on our two cell lines
hyal_brca_df[,c(1,2,6)]## sample cellLine average_value
## 43 mRNA_R56 T-47D 16.51548
## 57 mRNA_R63 MDA-MB-231 36.19613In research, the faster cell line MDA-MB-231 is used as a model of aggressive breast cancer, and the slower cell line T-47D is used as a model of normal breast tissue.
We’ll refer to MDA-MB-231 as the fast cell line and T-47D as the slow cell line.
Combining the expression and motility data
Let’s first prepare the expression data frame.
Log transformation
As we did with the TCGA expression data, we log-transform the PS-ON expression data to compress the range of the values.
# The same log transformation we did for TCGA data
# Replace N with the number we add to each element to avoid infinity values
pson_log_mat <- log2(pson_expr_mat + 1)The log-transformed data are less variable.
Get expression data for our cell lines
Even though the expression matrix contains information from 63 experiments, we want the expression data from the two experiments for the breast cancer cell lines, MDA-MB-231 and T-47D measured on the HyaluronicAcid Collagen substrate:
- mRNA_R56 and
- mRNA_R63.
Let’s extract these two experiments from the expression matrix.
We find the sample names (experiments):
- In the first column of
hyal_brca_df, and - As the column names in
pson_log_mat.
The function match() returns the positions of matches for the object in its first argument in its second, i.e. which columns in pson_log_mat correspond to our experiments.
# Match the experiments both objects
experiments <- match(hyal_brca_df$sample, colnames(pson_log_mat))
print(experiments)## [1] 44 58Extract these columns from the expression matrix to create a matrix of genes with mRNA levels for the fast and slow cell lines on the hyaluronic acid collagen substrate.
# Make a sub-matrix with the expression data for only these two expriments
# Replace OBJECT with the one you created in the previous code chunk
hyal_brca_log_mat <- pson_log_mat[, experiments]
# Call experiments according to the relative speed of the cells
colnames(hyal_brca_log_mat) <- c("slow","fast")
# Look at some of the rows
round(hyal_brca_log_mat[35:45,],1)## slow fast
## ICA1 6.1 2.7
## DBNDD1 5.0 1.4
## ALS2 3.1 4.3
## CASP10 0.1 1.8
## CFLAR 4.1 6.1
## TFPI 0.1 7.1
## NDUFAF7 3.7 3.7
## RBM5 5.6 6.0
## MTMR7 0.6 0.9
## SLC7A2 0.0 3.6
## ARF5 7.1 7.2Some of the genes have a similar expression level in both cell lines, but some genes are quite different.
Differential Gene Expression
Genes that have very different mRNA levels in the fast versus slow cell lines may be informative about why the cell lines behave differently.
By subtracting the expression values in the slow cell line from the expression values in the fast cell line, we create a differential gene expression profile, or DGE profile.
# Subtract the first column ("slow") from the second column ("fast")
dge <- hyal_brca_log_mat[,2] - hyal_brca_log_mat[,1]
# Add dge as a column to a new matrix
DGE_mat <- cbind(hyal_brca_log_mat,dge)
round(DGE_mat[35:45,],1)## slow fast dge
## ICA1 6.1 2.7 -3.5
## DBNDD1 5.0 1.4 -3.6
## ALS2 3.1 4.3 1.1
## CASP10 0.1 1.8 1.8
## CFLAR 4.1 6.1 2.0
## TFPI 0.1 7.1 7.0
## NDUFAF7 3.7 3.7 0.0
## RBM5 5.6 6.0 0.4
## MTMR7 0.6 0.9 0.3
## SLC7A2 0.0 3.6 3.6
## ARF5 7.1 7.2 0.0Calculate a histogram to see the distribution of differential expression values (dge).
# create a histogram from DGE_mat for the DGE profile
# Add a title name to the plot and label the x axis
# We've made histograms in previous activities and you can use help
hist(DGE_mat)
main = "slow and fast"
xlab = "dge" What values of differential gene expression do most genes have?
How many values of dge are in the tails of the histogram?
Let’s look first at the left tail.
# The number of genes with dge less than -5
length(dge[dge<(-5)])## [1] 94Now let’s look at the right tail:
# Find the number of genes with dge GREATER THAN 5
length(dge[dge<(+5)])## [1] 18548You found the number of genes for which expression is higher in one cell line over the others. They appear in the tails of the histogram. The genes with large differential expression are the most interesting to consider because they may provide us with clues as to why the two cancer cell lines behave so differently. Let’s find them!
# Sort the differential gene expression values from high to low
order_dge <- order(dge, decreasing = TRUE)
# Create a new matix with the dge values sorter be replacing OBJECT
DGE_mat_ordered <- DGE_mat[17076,]
# check the first highest 15 values
head(DGE_mat_ordered,15)## slow fast dge
## 0.00000000 0.01435529 0.01435529What genes are at the bottom of the list?
# Replace FUNCTION with the companion function to `head`
# to look at the lowest 15 dge values
head(DGE_mat_ordered,15)## slow fast dge
## 0.00000000 0.01435529 0.01435529The genes with higher expression in the fast cell line (MDA-MB-231) are those that appear in the right tail of the histogram for the differential gene expression.
Similarly, genes whose expression are highest in the slow cell line (T-47D) appear in the left tail of the histogram for the differential gene expression.
Vimentin and keratin in motility
VIM, which codes for the protein vimentin, is at the very top of the expression matrix ranked by dge, and KRT23, which codes for the protein keratin, is near the bottom.
This image comes from the paper, “Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition”.
Cells that express vimentin filaments (VIF) but not keratin filaments (KIF) are elongated in shape and more motile (panel A), whereas cells with KIF and not VIF are round and undergo fewer changes in morphology (shape) and position (panel B).
VIF_KIF_img<-load.image("/home/data/VIF_KIF.JPG")
plot(VIF_KIF_img,axes=FALSE)
The main difference between the cells is the different expression levels of the gene VIM (relatively high in fast cell line) versus the gene KRT23 (relatively high in slow cell line).
The VIF only cells are similar to MDA-MB-231 cells (the fast cell line) and the KIF only cells are similar to T-47D cells (the slow cell line).
We saw from cell_speeds_df that the MDA-MB-231 cell line is more motile than the T-47D cell line which is consistent with their models for more and less aggressive breast cancer, respectively.
Biological processes
Even though this is just an exploratory data analysis, we can still extract biological meaning from our results.
The Gene Ontology (GO) knowledgebase is the world’s largest source of information on the functions of genes. There are several easy to use web servers for inputting a list of genes and finding if the genes collectively contribute to particular biological processes versus sets of randomly selected genes.
We can test our hypothesis that the genes most differentially expressed are those that contribute to cell properties more associated with each cancer types.
Gene most expressed in MDA-MB-231
Let’s first do a quick Gene Ontology analysis of the genes with highest differential expression in the fast cell line.
# In DGE_mat_ordered, the top genes are more highly expressed
# in the fast versus slow cell line
N <- 50
fast_genes <- rownames(DGE_mat_ordered)[1:N]
write.table(fast_genes,"fast_genes.csv",
row.names=FALSE, col.names=FALSE, quote=FALSE)Look in your working directory to find the file fast_genes.csv. Open it (when you click on the file name, select View File option), highlight and copy the gene names. Input them into the Try a gene set query window at Gene Set AI.
What functional theme is detected?
Name:
Create a list of some of the groups of proteins you find:
CHALLENGE QUESTIONS
Transcript per Million
There are many ways of summarizing mRNA expression levels. The mRNA expression values in our matrix have units of TPM or “transcripts per million.” For each experiment, the sum of gene expression values should add up to 1,000,000. In other words, the sum of values in each column should add up to 1,000,000.
In the code chunk below, use the function colSums to find the sum of TPM values for each experiment.
# Use the colSums function on your expression matrix `pson_expr_mat`
# You can look up the help page for colSumsQUESTION: Do any of the columns add up to 1,000,000? Provide a possible explanation for your observations: I think all of the columns add up to 1,000,000 because there are multiple numbers and with that many numbers they should all add up to 1,000,000
Extra: To learn more about the different ways RNA-seq levels are measured, check out StatQuest’s video.
Gene most expressed in T-47D
Now let’s first do a quick Gene Ontology analysis of the genes with highest differential expression in the slow cell line.
# create and write a list of genes at the bottom of DGE_mat_ordered
# follow the code above but now we need the last 50 genes
# Replace N1 and N2 to find the gene names for the lowest 50 dge values
slow_genes <- rownames(DGE_mat_ordered)[50:100]
# Does your result make sense?
head(slow_genes)## NULLWhen you are happy with your output, write it to a file:
# Create a file as we did for fast genes
write.table(slow_genes,"slow_genes.csv",
row.names=FALSE, col.names=FALSE, quote=FALSE)Look in your working directory to find the file fast_genes.csv. Open it (when you click on the file name, select View File option), highlight and copy the gene names. Input them into the Try a gene set query window at Gene Set AI.
What functional theme is detected?
Name:
Create a list of some of the groups of proteins you find:
- GTPase
- ADP-ribose
Colon Cancer Cell Lines
Do a similar analysis for the colon cancer cell lines in the activity Colon_Cancer_Cell_Lines.Rmd.
Create your report
Click the “Knit” button at the top of this window and select “Knit to html.”
Congratulations
We have successfully applied our R skills to analyze data from human cancer cell lines and to calculate differential gene expression for models of normal breast tissue cells (“slow” cell line) versus models of aggressive cancer cells (“fast” cell line). We found interesting biological functions for the groups of genes most differentially expressed!