Phase_II_clinical_study (N=30)	Real_world (N=27)	P-value
Age
Mean (SD)	61.4 (8.28)	66.8 (9.20)	0.378
Median [Min, Max]	63.5 [38.0, 75.0]	67.0 [50.0, 85.0]
Sex
Female	5 (16.7%)	6 (22.2%)	0.846
Male	25 (83.3%)	21 (77.8%)
Smoking_history
Mean (SD)	0.733 (0.450)	0.630 (0.492)	0.578
Median [Min, Max]	1.00 [0, 1.00]	1.00 [0, 1.00]
Clinical_benefit_6months
DCB	18 (60.0%)	21 (77.8%)	0.694
NDB	8 (26.7%)	6 (22.2%)
Missing	4 (13.3%)	0 (0%)
Treatment
No.TRT	10 (33.3%)	13 (48.1%)	0.385
TRT	20 (66.7%)	14 (51.9%)
Immunotherapy_drug_type
PD-L1	30 (100%)	22 (81.5%)	0.0456
PD-1	0 (0%)	5 (18.5%)