TAC Only Analysis Notes
2025-07-07
Each tab can be clicked on to show off related statistics. All statistics have been computed using RStudio and all data was collected on VevoLab VevoStrain 2.0.
Results
Variable Definitions
| Variable_Name | Definition | Unit |
|---|---|---|
| mouse_ID | Label for each lab mouse | NA |
| study_type | What timepoint or unique study type | NA |
| true_mitral | 4DUS measured mitral valve area | mm |
| calc_mitral | Rounded mitral valve area used in VevoLab calculation | mm |
| true_aortic | 4DUS measured aortic valve area | mm |
| calc_aortic | Rounded aortic valve area used in VevoLab calculation | mm |
| sys_pk | Peak HDF value during systole | % |
| ewave_long_rms | Longitudinal RMS HDF value during diastolic E-wave | % |
| ewave_ratio_rms | Longitudinal to transverse RMS HDF value during diastolic E-wave | % |
| ewave_angle | Average HDF angle during diastolic E-wave | ° |
| cycle_length | Length of the entire heartbeat cycle | ms |
| cycle_long_rms | Longitudinal RMS HDF value during the entire heartbeat | % |
| cycle_trans_rms | Transverse RMS HDF value during the entire heartbeat | % |
| cycle_ratio_rms | Longitudinal to transverse RMS HDF value over the entire heartbeat | % |
| cycle_angle | Average HDF angle over the entire heartbeat | ° |
| sys_length | Length of systole | ms |
| sys_im_length | Length of systolic impulse | ms |
| sys_im_angle | Average HDF angle during systolic impulse | ° |
| sys_im_AUC | Area under the longitudinal curve during systolic impulse | % |
| sys_im_long_rms | Longitudinal RMS HDF value during the systolic impulse | % |
| sys_im_trans_rms | Transverse RMS HDF value during the systolic impulse | % |
| isys_im_length | Length of initial portion of systolic impulse | ms |
| isys_im_long_rms | Longitudinal RMS HDF value during the initial systolic impulse | % |
| dsys_im_length | Length of descending portion of systolic impulse | ms |
| dsys_im_long_rms | Longitudinal RMS HDF value during the descending systolic impulse | % |
| lsys_long_rms | Longitudinal RMS HDF value during the late systole period | % |
| myo_GCS | Myocardial global circumferential strain rate | % |
| myo_GLS | Myocardial global longitudinal strain rate | % |
| endo_GCS | Endocardial global circumferential strain rate | % |
| endo_GLS | Endocardial global longitudinal strain rate | % |
| LV_EF | LV Ejection fraction | % |
| LV_mass_cor | LV mass corrected mass | mg |
| LVAW_sys | LV anterior wall average thickness during systole | mm |
| LVAW_dias | LV anterior wall average thickness during diastole | mm |
| LVPW_sys | LV posterior wall average thickness during systole | mm |
| LVPW_dias | LV posterior wall average thickness during diastole | mm |
| sax_avg_strain | LV short axis average strain | % |
| LA_EF | LA ejection fraction | % |
| LA_edv | LA end diastolic volume | uL |
| LA_esv | LA end systolic volume | uL |
| LA_strain_mean | LA mean strain | % |
| Ao_pk_vel | Peak aoritc blood flow velocity | mm/s |
| sys_length_norm | Normalized systole length as a ratio of R to R | % |
| sys_im_length_norm | Normalized systolic impulse length as a ratio of R to R | % |
| isys_im_length_norm | Normalized initial systolic impulse length as a ratio of R to R | % |
| dsys_im_length_norm | Normalized descending systolic impulse length as a ratio of R to R | % |
| isys_dsys_length_ratio | Ratio of initial systolic impulse length to descending systolic impulse length | % |
| isys_dsys_long_ratio | Ratio of initial systolic impulse longitudinal HDF to descending systolic impulse longitudinal HDF | % |
Normality
Interpretation
Data Results
## === Normality Test for true_mitral ===
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## === Normality Test for calc_mitral ===
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## === Normality Test for true_aortic ===
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## === Normality Test for calc_aortic ===
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## === Normality Test for sys_pk ===
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## === Normality Test for ewave_long_rms ===
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## === Normality Test for ewave_ratio_rms ===
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## === Normality Test for ewave_angle ===
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## === Normality Test for cycle_length ===
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## === Normality Test for cycle_long_rms ===
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## === Normality Test for cycle_trans_rms ===
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## === Normality Test for cycle_ratio_rms ===
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## === Normality Test for cycle_angle ===
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## === Normality Test for sys_length ===
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## === Normality Test for sys_im_length ===
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## === Normality Test for sys_im_angle ===
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## === Normality Test for sys_im_AUC ===
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## === Normality Test for sys_im_long_rms ===
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## === Normality Test for sys_im_trans_rms ===
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## === Normality Test for isys_im_length ===
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## === Normality Test for isys_im_long_rms ===
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## === Normality Test for dsys_im_length ===
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## === Normality Test for dsys_im_long_rms ===
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## === Normality Test for lsys_long_rms ===
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## === Normality Test for myo_GCS ===
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## === Normality Test for myo_GLS ===
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## === Normality Test for endo_GCS ===
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## === Normality Test for endo_GLS ===
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## === Normality Test for sys_length_norm ===
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## === Normality Test for sys_im_length_norm ===
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## === Normality Test for isys_im_length_norm ===
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## === Normality Test for dsys_im_length_norm ===
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## === Normality Test for isys_dsys_length_ratio ===
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## === Normality Test for isys_dsys_long_ratio ===
## === Normality Test for LV_EF ===
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## === Normality Test for LV_mass_cor ===
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## === Normality Test for LVAW_sys ===
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## === Normality Test for LVAW_dias ===
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## === Normality Test for LVPW_sys ===
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## === Normality Test for LVPW_dias ===
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## === Normality Test for sax_avg_strain ===
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## === Normality Test for LA_EF ===
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## === Normality Test for LA_edv ===
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## === Normality Test for LA_esv ===
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## === Normality Test for LA_strain_mean ===
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## === Normality Test for Ao_pk_vel ===
Correlation
Interpretation
Plots
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'
## `geom_smooth()` using formula = 'y ~ x'