Main
Denis Ostroushko
Education
University of Minnesota School of Public Health
MS Biostatistics
Minneapolis, MN
2024 - 2022
University of Minnesota - Morris
BA Mathematics, Statistics (Double Major)
Morris, MN
2019 - 2015
Industry Experience
Sr. Healthcare Analyst
Medica
Minneapolis, MN
Present - June 2024
- Built predictive models to estimate recapture probability of HCCs for ACA and Medicare members, enabling targeted risk adjustment efforts. Currently leading development of interactive dashboards to monitor predicted vs. observed recapture outcomes in real time.
- Engineered methodology to allocate HHS transfer payments at the member level, creating a foundation for individualized profitability analysis. Used derived values to identify high-impact members for outreach and optimize revenue in ACA risk adjustment strategy.
- Designed and deployed a machine learning pipeline to forecast outcomes of chart review projects, including expected HCC yield and risk score increase. Integrated predictions into financial modeling to support budgeting, prioritization, and strategic investment in retrospective review initiatives.
Healthcare Analyst II
Medica
Minneapolis, MN
August 2023 - June 2021
- Led evaluation of a Transition of Care Program using Cox regression to estimate average treatment effect, translating clinical outcomes to financial impact. Proposed targeted improvements through subgroup analysis, estimating $200K (15%) in annualized value.
- Improved hospital readmission risk prediction by developing LASSO logistic regression and random forest models in R. Boosted predictive performance by 17% in AUC over previous production model.
- Designed a causal impact study using difference-in-differences with propensity score matching. Estimated variance via bootstrap and performed power analysis to guide next steps in program monitoring and scaling.
Healthcare Analyst I
Medica
Minneapolis, MN
June 2021 - June 2019
- Automated actuarial completion factor models in SAS/SQL, reducing prediction error by 35% and cutting delivery time from several days to under three hours.
- Advised cross-functional teams on ad hoc analyses, statistical inference from small samples, and cohort definitions to support affordability initiatives.
- Conducted medical cost and utilization trend analyses to support strategic planning. Created executive-ready presentations featuring ggplot-based visualizations, statistical insights, and narrative summaries of observed trends.
Academic Research Experience
Graduate Research Assistant
University of Minnesota, Division of Biostatistics
Minneapolis, MN
May 2024 - August 2023
Data Integration Predictive Methods for AD Identification
- Developed a machine learning pipeline to identify key predictors of Alzheimer’s Disease (AD) across multiple -omics data types (e.g., genomics, proteomics).
- Applied SIDA, a novel data-integration method, to perform multi-view feature selection and infer biologically relevant AD biomarkers.
- Demonstrated that integrating multiple -omics sources improved classification AUC by 10–20% over single-view models.
Publications
Sandra E Safo PhD, Thierry Chekouo PhD, Denis Ostroushko, et al.
A score based on MRI imaging variables can predict time to moderate progression in Mild Cognitive Impairment: multimodal data integration study,
The Journal of the Alzheimer’s Association - Under Review , 2025
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Stephen Vincent Burks PhD, Jon Eugene Anderson PhD, Denis Ostroushko, et al.
The Pre-Registry Commercial Driver Medical Examination: Screening Sensitivity and Certification Lengths for Two Safety-Related Medical Conditions
Journal of Occupational and Environmental Medicine, 2020.
10.1097/JOM.0000000000001816
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Personal Projects
Interactive Analysis of Soccer Data
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Present - April 2023
- Built a ShinyApp to explore player-level soccer data from FBRef.com, featuring interactive tables, charts, and similarity metrics.
- Automated daily data collection using
GitHub Actionsand stored historical data inAWS S3for reproducibility and scale. - Implemented custom distance metrics to compare players across seasons using high-dimensional performance features and visualized similarities with
plotly.
Amateur Soccer Team Performance Tracking
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Present - April 2023