| Serum Lab Values |
| Serum WBC (IQR) |
8.17 [5.68, 11.40] |
8.57 [6.17, 11.49] |
5.10 [3.15, 8.38] |
<0.001 |
80 |
Serum Lab Values |
| CSF Lab Values |
| CSF Admission Day (IQR) |
1.00 [0.85, 4.00] |
1.00 [0.00, 3.00] |
4.00 [1.00, 11.00] |
<0.001 |
65 |
CSF Lab Values |
| CSF Protein (IQR) |
47.50 [31.70, 78.05] |
48.00 [31.00, 78.00] |
46.55 [33.92, 80.03] |
0.935 |
66 |
CSF Lab Values |
| CSF Total Protein < 60, n (%) |
834 (64.0) |
722 (63.7) |
112 (65.9) |
0.645 |
68 |
CSF Lab Values |
| CSF Total Protein ≥ 60, n (%) |
469 (36.0) |
411 (36.3) |
58 (34.1) |
0.645 |
69 |
CSF Lab Values |
| CSF Glucose (IQR) |
68.00 [58.00, 85.00] |
68.00 [58.00, 84.50] |
67.00 [57.50, 88.50] |
0.890 |
70 |
CSF Lab Values |
| CSF Total Nucleated Cell Count (IQR) |
3.00 [1.00, 21.00] |
3.00 [1.00, 23.00] |
3.00 [1.00, 12.50] |
0.463 |
71 |
CSF Lab Values |
| CSF Total Nucleated Cell Count < 5, n (%) |
769 (59.0) |
665 (58.7) |
104 (60.8) |
0.658 |
73 |
CSF Lab Values |
| CSF Total Nucleated Cell Count ≥ 5, n (%) |
535 (41.0) |
468 (41.3) |
67 (39.2) |
0.658 |
74 |
CSF Lab Values |
| CSF Lymphocyte Count (IQR) |
66.00 [25.00, 86.00] |
65.00 [25.00, 86.00] |
66.00 [20.50, 87.00] |
0.691 |
75 |
CSF Lab Values |
| Normal CSF Cell Count (CSF TNC < 5), n (%) |
769 (59.0) |
665 (58.7) |
104 (60.8) |
0.651 |
77 |
CSF Lab Values |
| Pleocytosis (Lymph ≥ 50%), n (%) |
350 (26.8) |
309 (27.3) |
41 (24.0) |
0.651 |
78 |
CSF Lab Values |
| Pleocytosis (Lymph < 50%), n (%) |
185 (14.2) |
159 (14.0) |
26 (15.2) |
0.651 |
79 |
CSF Lab Values |
| Seasonal Testing |
| Test Sent Off-Season, n (%) |
479 (36.7) |
409 (36.1) |
70 (40.9) |
0.255 |
63 |
Seasonal Testing |
| Test Sent June-Nov, n (%) |
825 (63.3) |
724 (63.9) |
101 (59.1) |
0.255 |
64 |
Seasonal Testing |
| Clinical History |
| Neurology, n (%) |
584 (44.8) |
564 (49.8) |
20 (11.7) |
<0.001 |
47 |
Clinical History |
| Neurology, n (%) |
584 (44.8) |
564 (49.8) |
20 (11.7) |
<0.001 |
47 |
Clinical History |
| Medicine/Subspecialties, n (%) |
456 (35.0) |
403 (35.6) |
53 (31.0) |
<0.001 |
48 |
Clinical History |
| Oncology, n (%) |
178 (13.7) |
96 (8.5) |
82 (48.0) |
<0.001 |
49 |
Clinical History |
| Other, n (%) |
86 (6.6) |
70 (6.2) |
16 (9.4) |
<0.001 |
50 |
Clinical History |
| Non-Neurology, n (%) |
720 (55.2) |
569 (50.2) |
151 (88.3) |
<0.001 |
52 |
Clinical History |
| Immunocompetent, n (%) |
1133 (86.9) |
1133 (100.0) |
0 (0.0) |
<0.001 |
54 |
Clinical History |
| Immunosuppressed, n (%) |
171 (13.1) |
0 (0.0) |
171 (100.0) |
<0.001 |
55 |
Clinical History |
| No Transplant, n (%) |
1160 (89.0) |
1133 (100.0) |
27 (15.8) |
<0.001 |
57 |
Clinical History |
| History of Transplant, n (%) |
144 (11.0) |
0 (0.0) |
144 (84.2) |
<0.001 |
58 |
Clinical History |
| No B-cell Depleting Meds, n (%) |
1271 (97.5) |
1133 (100.0) |
138 (80.7) |
<0.001 |
60 |
Clinical History |
| B-cell Depletion, n (%) |
33 (2.5) |
0 (0.0) |
33 (19.3) |
<0.001 |
61 |
Clinical History |
| CDC WNV Testing Guideline Adherence |
| Adherent, n (%) |
335 (25.7) |
321 (28.3) |
14 (8.2) |
<0.001 |
44 |
CDC WNV Testing Guideline Adherence |
| Nonadherent, n (%) |
969 (74.3) |
812 (71.7) |
157 (91.8) |
<0.001 |
45 |
CDC WNV Testing Guideline Adherence |
| Serum West Nile Virus IgM |
| Serum IgM Ordered No, n (%) |
1169 (89.6) |
1014 (89.5) |
155 (90.6) |
0.746 |
36 |
Serum West Nile Virus IgM |
| Serum IgM Ordered Yes, n (%) |
135 (10.4) |
119 (10.5) |
16 (9.4) |
0.746 |
37 |
Serum West Nile Virus IgM |
| No Result, n (%) |
14 (1.1) |
14 (1.2) |
0 (0.0) |
0.262 |
39 |
Serum West Nile Virus IgM |
| Positive, n (%) |
11 (0.8) |
11 (1.0) |
0 (0.0) |
0.262 |
40 |
Serum West Nile Virus IgM |
| Negative, n (%) |
110 (8.4) |
94 (8.3) |
16 (9.4) |
0.262 |
41 |
Serum West Nile Virus IgM |
| Not Ordered, n (%) |
1169 (89.6) |
1014 (89.5) |
155 (90.6) |
0.262 |
42 |
Serum West Nile Virus IgM |
| CSF West Nile Virus IgM |
| CSF IgM Ordered No, n (%) |
951 (72.9) |
812 (71.7) |
139 (81.3) |
0.011 |
28 |
CSF West Nile Virus IgM |
| CSF IgM Ordered Yes, n (%) |
353 (27.1) |
321 (28.3) |
32 (18.7) |
0.011 |
29 |
CSF West Nile Virus IgM |
| CSF IgM No Result, n (%) |
63 (4.8) |
58 (5.1) |
5 (2.9) |
0.060 |
31 |
CSF West Nile Virus IgM |
| CSF IgM Positive, n (%) |
20 (1.5) |
19 (1.7) |
1 (0.6) |
0.060 |
32 |
CSF West Nile Virus IgM |
| CSF IgM Negative, n (%) |
270 (20.7) |
244 (21.5) |
26 (15.2) |
0.060 |
33 |
CSF West Nile Virus IgM |
| CSF IgM Not Ordered, n (%) |
951 (72.9) |
812 (71.7) |
139 (81.3) |
0.060 |
34 |
CSF West Nile Virus IgM |
| CSF West Nile Virus RT-PCR |
| CSF PCR Ordered No, n (%) |
171 (13.1) |
153 (13.5) |
18 (10.5) |
0.340 |
20 |
CSF West Nile Virus RT-PCR |
| CSF PCR Ordered Yes, n (%) |
1133 (86.9) |
980 (86.5) |
153 (89.5) |
0.340 |
21 |
CSF West Nile Virus RT-PCR |
| CSF PCR No Result, n (%) |
38 (2.9) |
37 (3.3) |
1 (0.6) |
0.116 |
23 |
CSF West Nile Virus RT-PCR |
| CSF PCR Positive, n (%) |
4 (0.3) |
4 (0.4) |
0 (0.0) |
0.116 |
24 |
CSF West Nile Virus RT-PCR |
| CSF PCR Negative, n (%) |
1091 (83.7) |
939 (82.9) |
152 (88.9) |
0.116 |
25 |
CSF West Nile Virus RT-PCR |
| CSF PCR Not Ordered, n (%) |
171 (13.1) |
153 (13.5) |
18 (10.5) |
0.116 |
26 |
CSF West Nile Virus RT-PCR |
| CSF Test Ordering |
| PCR Only, n (%) |
951 (72.9) |
812 (71.7) |
139 (81.3) |
0.023 |
16 |
CSF Test Ordering |
| IgM Only, n (%) |
171 (13.1) |
153 (13.5) |
18 (10.5) |
0.023 |
17 |
CSF Test Ordering |
| Both PCR & IgM, n (%) |
182 (14.0) |
168 (14.8) |
14 (8.2) |
0.023 |
18 |
CSF Test Ordering |
| Demographics |
| Male, n (%) |
703 (53.9) |
600 (53.0) |
103 (60.2) |
0.090 |
2 |
Demographics |
| Female, n (%) |
601 (46.1) |
533 (47.0) |
68 (39.8) |
0.090 |
3 |
Demographics |
| Median Age (IQR) |
63.00 [48.00, 73.00] |
63.00 [47.00, 73.15] |
65.00 [57.50, 71.50] |
0.108 |
4 |
Demographics |
| Not Reported Dead, n (%) |
915 (70.2) |
838 (74.0) |
77 (45.0) |
<0.001 |
7 |
Demographics |
| Reported Dead, n (%) |
389 (29.8) |
295 (26.0) |
94 (55.0) |
<0.001 |
8 |
Demographics |
| Other Insurance, n (%) |
933 (71.5) |
808 (71.3) |
125 (73.1) |
0.696 |
10 |
Demographics |
| Medicaid/Safety Net, n (%) |
371 (28.5) |
325 (28.7) |
46 (26.9) |
0.696 |
11 |
Demographics |
| Mass General Hospital, n (%) |
706 (54.1) |
655 (57.8) |
51 (29.8) |
<0.001 |
13 |
Demographics |
| Brigham and Women's Hospital, n (%) |
598 (45.9) |
478 (42.2) |
120 (70.2) |
<0.001 |
14 |
Demographics |