Preliminary Results with Known Issue Affecting Small Number of Sister Study Participants

Primary
Outcome Person Years Events HR Lower HR Est. HR Upper p Value Parameter Est. Std. Error
PM2.5 Non-accidental Mortality 7,687,414 132,205 1.019 1.028 1.038 <.0001 0.0093 0.0016
CVD Mortality 7,148,127 33,279 1.045 1.067 1.089 <.0001 0.0215 0.0035
Cardiovascular Disease 7,257,889 70,623 1.036 1.049 1.062 <.0001 0.0159 0.0021
Myocardial Infarction 6,428,266 30,639 1.037 1.057 1.077 <.0001 0.0185 0.0032
Stroke 6,370,430 27,376 1.007 1.026 1.046 0.0088 0.0087 0.0033
NO2 Non-accidental Mortality 7,687,414 132,205 1.022 1.031 1.040 <.0001 0.0051 0.0007
CVD Mortality 7,148,127 33,279 1.033 1.055 1.076 <.0001 0.0089 0.0017
Cardiovascular Disease 7,257,889 70,623 1.008 1.020 1.033 0.0015 0.0033 0.0010
Myocardial Infarction 6,428,266 30,639 1.019 1.038 1.058 <.0001 0.0063 0.0016
Stroke 6,370,430 27,376 0.979 0.997 1.017 0.7930 −0.0004 0.0016
O3 Non-accidental Mortality 7,687,414 132,205 0.983 0.991 1.000 0.0488 −0.0017 0.0009
CVD Mortality 6,342,847 33,085 0.977 0.995 1.014 0.6282 −0.0009 0.0019
Cardiovascular Disease 7,257,889 70,623 0.978 0.989 1.001 0.0640 −0.0022 0.0012
Myocardial Infarction 6,428,266 30,639 0.967 0.984 1.001 0.0672 −0.0032 0.0018
Stroke 6,370,430 27,376 0.950 0.967 0.985 0.0003 −0.0067 0.0019