| Variable | No SLD N = 881 |
MASLD N = 4121 |
MetALD N = 141 |
ALD N = 171 |
p-value2 |
|---|---|---|---|---|---|
| sex | <0.001 | ||||
| Female | 44 (50%) | 207 (50%) | 2 (14%) | 2 (12%) | |
| Male | 44 (50%) | 205 (50%) | 12 (86%) | 15 (88%) | |
| age | 58 (10) | 50 (15) | 56 (8) | 55 (10) | <0.001 |
| BMI | 24.3 (3.4) | 28.1 (3.8) | 25.1 (4.6) | 24.7 (3.5) | <0.001 |
| Hb | 13.27 (1.50) | 14.14 (1.54) | 14.09 (1.71) | 13.83 (1.68) | <0.001 |
| PLT | 231 (67) | 244 (64) | 211 (32) | 235 (105) | 0.015 |
| AST | 35 (33) | 55 (41) | 60 (48) | 64 (84) | <0.001 |
| ALT | 37 (50) | 76 (66) | 71 (55) | 84 (151) | <0.001 |
| ALP | 101 (79) | 89 (51) | 128 (84) | 110 (132) | 0.3 |
| GGT | 111 (200) | 73 (100) | 238 (257) | 290 (452) | <0.001 |
| GGT_cat | 0.001 | ||||
| _normal | 50 (57%) | 204 (50%) | 1 (7.1%) | 4 (25%) | |
| _elevated | 37 (43%) | 207 (50%) | 13 (93%) | 12 (75%) | |
| Alb | 4.04 (0.29) | 4.29 (0.34) | 4.15 (0.50) | 4.12 (0.38) | <0.001 |
| Tbil | 0.85 (0.38) | 0.81 (0.41) | 0.85 (0.31) | 0.97 (0.42) | 0.3 |
| Cr | 0.77 (0.16) | 0.79 (0.20) | 0.75 (0.25) | 0.82 (0.20) | 0.7 |
| Cholesterol | 182 (40) | 184 (41) | 203 (52) | 184 (37) | 0.5 |
| HDL | 54 (15) | 46 (12) | 53 (15) | 53 (14) | <0.001 |
| TG | 128 (103) | 168 (148) | 156 (58) | 157 (65) | <0.001 |
| Glucose | 112 (33) | 115 (33) | 123 (38) | 111 (18) | 0.3 |
| hba1c | 5.83 (0.53) | 6.27 (1.10) | 6.24 (0.84) | 5.99 (0.85) | 0.011 |
| hsCRP | 0.25 (0.54) | 0.35 (1.45) | 0.44 (0.56) | 0.16 (0.20) | <0.001 |
| DB상 HTN(+) | 28 (32%) | 179 (43%) | 6 (43%) | 7 (41%) | 0.3 |
| DB상 DL(+) | 29 (33%) | 163 (40%) | 6 (43%) | 4 (24%) | 0.4 |
| Glucose 126이상, HbA1c 6.5이상 OR 투약(+) | 24 (28%) | 157 (38%) | 6 (43%) | 6 (35%) | 0.3 |
| Alcohol_c | |||||
| Non alcoholics | 46 (52%) | 311 (75%) | 0 (0%) | 0 (0%) | |
| (M) ~30 g/d, (F) ~20 g/d | 24 (27%) | 101 (25%) | 0 (0%) | 0 (0%) | |
| (M) 31-60 g/d, (F) 21-50 g/d | 9 (10%) | 0 (0%) | 14 (100%) | 0 (0%) | |
| (M) >60 g/d, (F) 50 g/d | 9 (10%) | 0 (0%) | 0 (0%) | 17 (100%) | |
| FIB4 (자동계산) | 1.60 (0.85) | 1.51 (1.08) | 1.98 (1.10) | 2.09 (1.28) | 0.004 |
| APRI (자동계산) | 0.39 (0.35) | 0.60 (0.50) | 0.72 (0.56) | 0.77 (1.04) | <0.001 |
| Agile 3+ score (계산) | 0.20 (0.18) | 0.24 (0.23) | 0.28 (0.23) | 0.29 (0.27) | 0.7 |
| Agile 4 score (계산) | 0.03 (0.05) | 0.04 (0.07) | 0.03 (0.04) | 0.07 (0.13) | 0.5 |
| Bx_Fibrosis_2 | |||||
| 0 | 50 (57%) | 70 (17%) | 2 (14%) | 4 (24%) | |
| 1 | 27 (31%) | 229 (56%) | 8 (57%) | 8 (47%) | |
| 2 | 7 (8.0%) | 83 (20%) | 2 (14%) | 2 (12%) | |
| 3 | 4 (4.5%) | 20 (4.9%) | 2 (14%) | 3 (18%) | |
| 4 | 0 (0%) | 10 (2.4%) | 0 (0%) | 0 (0%) | |
| LSM_kPa | 4.88 (1.72) | 6.20 (1.86) | 5.79 (2.12) | 5.81 (1.75) | <0.001 |
| LSM_F | 0.002 | ||||
| ≤1 | 73 (83%) | 248 (60%) | 10 (71%) | 13 (76%) | |
| 2 | 9 (10%) | 90 (22%) | 1 (7.1%) | 2 (12%) | |
| 3 | 6 (6.8%) | 74 (18%) | 3 (21%) | 2 (12%) | |
| 4 | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | |
| CAP score | 236 (45) | 296 (61) | 289 (44) | 275 (71) | <0.001 |
| Fibrosis_increase | 17 (19%) | 123 (30%) | 5 (36%) | 5 (29%) | 0.2 |
| Fibrosis_decrease | 13 (15%) | 125 (30%) | 3 (21%) | 3 (18%) | 0.015 |
| 1 n (%); Mean (SD) | |||||
| 2 Pearson’s Chi-squared test; Kruskal-Wallis rank sum test; Fisher’s exact test | |||||