#To do:
From Tim: instead of log-MFI, do ratio to total IgG, then take the
log
- restrict TMLE to only those with repeated measures as sensitivty
analyis, and add IPTW as alternative sensitivity analysis -add glm
sensitivity results (bivariate and multivariate)
- add to table of incidence of different pathogens by round
- Sort the bar charts correctly with r1 at the top -figure out missing
TMLE estimates -tabulate number and proportion of individuals with
saliva samples
- look at seasonality of results -look at the FMM outcomes (T.gondii
and H-pylori) as regression/tmle outcomes (should vary by
demographics)
Balance tables
Table 1:
R1 |
33 |
83 |
Overall |
R2 |
23 |
65 |
Overall |
R3 |
19 |
49 |
Overall |
R1 |
27 |
65 |
Utility Water |
R1 |
6 |
18 |
Non-utility Water |
R2 |
19 |
49 |
Utility Water |
R2 |
4 |
16 |
Non-utility Water |
R3 |
15 |
35 |
Utility Water |
R3 |
4 |
14 |
Non-utility Water |
R1 |
14 |
40 |
Bottled water |
R1 |
3 |
9 |
Spring water |
R1 |
13 |
25 |
Utility Water |
R1 |
3 |
9 |
Well water |
R2 |
9 |
27 |
Bottled water |
R2 |
1 |
5 |
Spring water |
R2 |
11 |
27 |
Utility Water |
R2 |
2 |
6 |
Well water |
R3 |
7 |
16 |
Bottled water |
R3 |
2 |
9 |
Spring water |
R3 |
8 |
19 |
Utility Water |
R3 |
2 |
5 |
Well water |
Table 1:
n |
83 |
65 |
18 |
Head of household: female = Male (%) |
16 (48.5) |
12 (44.4) |
4 ( 66.7) |
Head of household: age (mean (SD)) |
58.97 (14.54) |
60.78 (13.77) |
50.83 (16.40) |
Head of household: education (%) |
|
|
|
Community college or higher |
28 (33.7) |
20 (30.8) |
8 ( 44.4) |
High school graduate |
42 (50.6) |
32 (49.2) |
10 ( 55.6) |
Less than a high school education |
13 (15.7) |
13 (20.0) |
0 ( 0.0) |
Household members: female = Female (%) |
46 (55.4) |
37 (56.9) |
9 ( 50.0) |
Household members: age (mean (SD)) |
40.99 (24.62) |
43.08 (24.58) |
33.44 (23.94) |
Household members: ethnicity = White (%) |
77 (92.8) |
64 (98.5) |
13 ( 72.2) |
Household income (%) |
|
|
|
<$15k |
29 (34.9) |
22 (33.8) |
7 ( 38.9) |
$15k-$20k |
10 (12.0) |
6 ( 9.2) |
4 ( 22.2) |
$20k-$25k |
8 ( 9.6) |
8 (12.3) |
0 ( 0.0) |
$25k-$30k |
26 (31.3) |
22 (33.8) |
4 ( 22.2) |
$35k-$40k |
5 ( 6.0) |
5 ( 7.7) |
0 ( 0.0) |
$40k-$45k |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
>$50k |
5 ( 6.0) |
2 ( 3.1) |
3 ( 16.7) |
Don’t want to say |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
Working toilet, sink, tub/shower (%) |
|
|
|
Toilet & shower |
6 ( 7.2) |
6 ( 9.2) |
0 ( 0.0) |
Toilet & sink |
4 ( 4.8) |
4 ( 6.2) |
0 ( 0.0) |
Yes, all work |
73 (88.0) |
55 (84.6) |
18 (100.0) |
Sanitary sewer, septic, or straight pipe (%) |
|
|
|
Septic tank & drainfield |
36 (43.4) |
18 (27.7) |
18 (100.0) |
Straight pipe |
2 ( 2.4) |
2 ( 3.1) |
0 ( 0.0) |
Utility sewer connection |
45 (54.2) |
45 (69.2) |
0 ( 0.0) |
Time to healthcare facility if minor issue (minutes)
(mean (SD)) |
14.76 (9.79) |
13.15 (9.18) |
20.56 (9.98) |
Time to healthcare facility if major issue (minutes)
(mean (SD)) |
41.25 (27.28) |
36.37 (22.69) |
58.89 (35.09) |
Table 1:
n |
197 |
83 |
65 |
49 |
Head of household: female (%) |
|
|
|
|
Female |
23 (11.7) |
17 (20.5) |
0 ( 0.0) |
6 (12.2) |
Male |
30 (15.2) |
16 (19.3) |
0 ( 0.0) |
14 (28.6) |
NA |
144 (73.1) |
50 (60.2) |
65 (100.0) |
29 (59.2) |
Head of household: age (mean (SD)) |
59.28 (14.84) |
58.97 (14.54) |
NaN (NA) |
59.80 (15.70) |
Head of household: education (%) |
|
|
|
|
Community college or higher |
57 (28.9) |
28 (33.7) |
19 ( 29.2) |
10 (20.4) |
High school graduate |
101 (51.3) |
42 (50.6) |
36 ( 55.4) |
23 (46.9) |
Less than a high school education |
39 (19.8) |
13 (15.7) |
10 ( 15.4) |
16 (32.7) |
Household members: female = Female (%) |
109 (55.3) |
46 (55.4) |
34 ( 52.3) |
29 (59.2) |
Household members: age (mean (SD)) |
41.87 (24.13) |
40.99 (24.62) |
40.49 (24.16) |
45.18 (23.44) |
Household members: ethnicity = White (%) |
182 (92.4) |
77 (92.8) |
57 ( 87.7) |
48 (98.0) |
Household income (%) |
|
|
|
|
<$15k |
42 (21.3) |
29 (34.9) |
0 ( 0.0) |
13 (26.5) |
$15k-$20k |
25 (12.7) |
10 (12.0) |
0 ( 0.0) |
15 (30.6) |
$20k-$25k |
18 ( 9.1) |
8 ( 9.6) |
0 ( 0.0) |
10 (20.4) |
$25k-$30k |
31 (15.7) |
26 (31.3) |
0 ( 0.0) |
5 (10.2) |
$35k-$40k |
5 ( 2.5) |
5 ( 6.0) |
0 ( 0.0) |
0 ( 0.0) |
$40k-$45k |
2 ( 1.0) |
0 ( 0.0) |
0 ( 0.0) |
2 ( 4.1) |
>$50k |
5 ( 2.5) |
5 ( 6.0) |
0 ( 0.0) |
0 ( 0.0) |
Don’t want to say |
4 ( 2.0) |
0 ( 0.0) |
0 ( 0.0) |
4 ( 8.2) |
NA |
65 (33.0) |
0 ( 0.0) |
65 (100.0) |
0 ( 0.0) |
Working toilet, sink, tub/shower (%) |
|
|
|
|
Toilet & shower |
16 ( 8.1) |
6 ( 7.2) |
8 ( 12.3) |
2 ( 4.1) |
Toilet & sink |
4 ( 2.0) |
4 ( 4.8) |
0 ( 0.0) |
0 ( 0.0) |
Yes, all work |
177 (89.8) |
73 (88.0) |
57 ( 87.7) |
47 (95.9) |
Sanitary sewer, septic, or straight pipe (%) |
|
|
|
|
Other |
2 ( 1.0) |
0 ( 0.0) |
0 ( 0.0) |
2 ( 4.1) |
Septic tank & drainfield |
91 (46.2) |
36 (43.4) |
27 ( 41.5) |
28 (57.1) |
Septic tank but no drainfield |
9 ( 4.6) |
0 ( 0.0) |
9 ( 13.8) |
0 ( 0.0) |
Straight pipe |
8 ( 4.1) |
2 ( 2.4) |
4 ( 6.2) |
2 ( 4.1) |
Utility sewer connection |
87 (44.2) |
45 (54.2) |
25 ( 38.5) |
17 (34.7) |
Time to healthcare facility if minor issue (minutes)
(mean (SD)) |
15.95 (10.24) |
14.76 (9.79) |
18.37 (9.55) |
14.79 (11.51) |
Time to healthcare facility if major issue (minutes)
(mean (SD)) |
43.25 (29.77) |
41.25 (27.28) |
45.74 (31.30) |
43.53 (32.27) |
Table 1:
n |
197 |
65 |
18 |
49 |
16 |
35 |
14 |
Head of household: female (%) |
|
|
|
|
|
|
|
Female |
23 (11.7) |
15 (23.1) |
2 ( 11.1) |
0 ( 0.0) |
0 ( 0.0) |
6 (17.1) |
0 ( 0.0) |
Male |
30 (15.2) |
12 (18.5) |
4 ( 22.2) |
0 ( 0.0) |
0 ( 0.0) |
10 (28.6) |
4 ( 28.6) |
NA |
144 (73.1) |
38 (58.5) |
12 ( 66.7) |
49 (100.0) |
16 (100.0) |
19 (54.3) |
10 ( 71.4) |
Head of household: age (mean (SD)) |
59.28 (14.84) |
60.78 (13.77) |
50.83 (16.40) |
NaN (NA) |
NaN (NA) |
61.19 (15.58) |
54.25 (17.19) |
Head of household: education (%) |
|
|
|
|
|
|
|
Community college or higher |
57 (28.9) |
20 (30.8) |
8 ( 44.4) |
13 ( 26.5) |
6 ( 37.5) |
5 (14.3) |
5 ( 35.7) |
High school graduate |
101 (51.3) |
32 (49.2) |
10 ( 55.6) |
26 ( 53.1) |
10 ( 62.5) |
14 (40.0) |
9 ( 64.3) |
Less than a high school education |
39 (19.8) |
13 (20.0) |
0 ( 0.0) |
10 ( 20.4) |
0 ( 0.0) |
16 (45.7) |
0 ( 0.0) |
Household members: female = Female (%) |
109 (55.3) |
37 (56.9) |
9 ( 50.0) |
28 ( 57.1) |
6 ( 37.5) |
21 (60.0) |
8 ( 57.1) |
Household members: age (mean (SD)) |
41.87 (24.13) |
43.08 (24.58) |
33.44 (23.94) |
42.94 (24.06) |
33.00 (23.63) |
48.49 (22.74) |
36.93 (23.95) |
Household members: ethnicity = White (%) |
182 (92.4) |
64 (98.5) |
13 ( 72.2) |
46 ( 93.9) |
11 ( 68.8) |
34 (97.1) |
14 (100.0) |
Household income (%) |
|
|
|
|
|
|
|
<$15k |
42 (21.3) |
22 (33.8) |
7 ( 38.9) |
0 ( 0.0) |
0 ( 0.0) |
10 (28.6) |
3 ( 21.4) |
$15k-$20k |
25 (12.7) |
6 ( 9.2) |
4 ( 22.2) |
0 ( 0.0) |
0 ( 0.0) |
15 (42.9) |
0 ( 0.0) |
$20k-$25k |
18 ( 9.1) |
8 (12.3) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
5 (14.3) |
5 ( 35.7) |
$25k-$30k |
31 (15.7) |
22 (33.8) |
4 ( 22.2) |
0 ( 0.0) |
0 ( 0.0) |
5 (14.3) |
0 ( 0.0) |
$35k-$40k |
5 ( 2.5) |
5 ( 7.7) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
$40k-$45k |
2 ( 1.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
2 ( 14.3) |
>$50k |
5 ( 2.5) |
2 ( 3.1) |
3 ( 16.7) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
Don’t want to say |
4 ( 2.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
4 ( 28.6) |
NA |
65 (33.0) |
0 ( 0.0) |
0 ( 0.0) |
49 (100.0) |
16 (100.0) |
0 ( 0.0) |
0 ( 0.0) |
Working toilet, sink, tub/shower (%) |
|
|
|
|
|
|
|
Toilet & shower |
16 ( 8.1) |
6 ( 9.2) |
0 ( 0.0) |
8 ( 16.3) |
0 ( 0.0) |
2 ( 5.7) |
0 ( 0.0) |
Toilet & sink |
4 ( 2.0) |
4 ( 6.2) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
Yes, all work |
177 (89.8) |
55 (84.6) |
18 (100.0) |
41 ( 83.7) |
16 (100.0) |
33 (94.3) |
14 (100.0) |
Sanitary sewer, septic, or straight pipe (%) |
|
|
|
|
|
|
|
Other |
2 ( 1.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
2 ( 5.7) |
0 ( 0.0) |
Septic tank & drainfield |
91 (46.2) |
18 (27.7) |
18 (100.0) |
20 ( 40.8) |
7 ( 43.8) |
14 (40.0) |
14 (100.0) |
Septic tank but no drainfield |
9 ( 4.6) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
9 ( 56.2) |
0 ( 0.0) |
0 ( 0.0) |
Straight pipe |
8 ( 4.1) |
2 ( 3.1) |
0 ( 0.0) |
4 ( 8.2) |
0 ( 0.0) |
2 ( 5.7) |
0 ( 0.0) |
Utility sewer connection |
87 (44.2) |
45 (69.2) |
0 ( 0.0) |
25 ( 51.0) |
0 ( 0.0) |
17 (48.6) |
0 ( 0.0) |
Time to healthcare facility if minor issue (minutes)
(mean (SD)) |
15.95 (10.24) |
13.15 (9.18) |
20.56 (9.98) |
16.44 (8.66) |
24.06 (10.04) |
16.03 (12.90) |
11.86 (6.77) |
Time to healthcare facility if major issue (minutes)
(mean (SD)) |
43.25 (29.77) |
36.37 (22.69) |
58.89 (35.09) |
43.88 (33.47) |
53.33 (19.46) |
46.52 (35.59) |
36.50 (22.17) |
Water quality tables
Note 1) Nitrate_ppm is not in the raw data, so using
wNitrate.NO3 instead 2) drop[ed] one sample not matched to a household
(sample code “122299spring” - roadside spring)
Tap (Exposure) water quality table
n |
75 |
27 |
6 |
19 |
4 |
15 |
4 |
wFphM (mean (SD)) |
7.83 (0.37) |
7.74 (0.38) |
7.74 (0.35) |
7.94 (0.33) |
7.96 (0.54) |
7.86 (0.39) |
7.83 (0.43) |
wFtempM (mean (SD)) |
18.72 (4.79) |
22.83 (2.11) |
22.13 (1.34) |
13.75 (2.83) |
11.74 (5.88) |
17.95 (2.65) |
19.41 (2.91) |
wFcondM (mean (SD)) |
334.17 (218.52) |
332.29 (265.20) |
415.00 (156.77) |
325.46 (188.26) |
445.25 (60.41) |
256.56 (204.87) |
446.88 (195.37) |
bTC (mean (SD)) |
0.29 (0.46) |
0.19 (0.40) |
0.83 (0.41) |
0.16 (0.37) |
1.00 (0.00) |
0.07 (0.26) |
1.00 (0.00) |
wTCmpn_M (mean (SD)) |
65.74 (295.74) |
15.90 (67.48) |
514.38 (963.97) |
0.13 (0.37) |
113.74 (125.31) |
34.76 (134.62) |
109.07 (80.17) |
bEC (mean (SD)) |
0.07 (0.25) |
0.00 (0.00) |
0.33 (0.52) |
0.00 (0.00) |
0.25 (0.50) |
0.00 (0.00) |
0.50 (0.58) |
wECmpn_M (mean (SD)) |
0.92 (5.98) |
0.00 (0.00) |
10.17 (20.32) |
0.00 (0.00) |
0.76 (1.52) |
0.00 (0.00) |
1.30 (1.73) |
Arsenic (mean (SD)) |
0.14 (0.25) |
0.07 (0.08) |
0.30 (0.51) |
0.13 (0.06) |
0.63 (0.66) |
0.06 (0.05) |
0.21 (0.33) |
Barium_ppm (mean (SD)) |
0.04 (0.04) |
0.03 (0.02) |
0.07 (0.07) |
0.03 (0.01) |
0.11 (0.08) |
0.03 (0.01) |
0.10 (0.06) |
Cadmium (mean (SD)) |
0.02 (0.05) |
0.01 (0.05) |
0.02 (0.04) |
0.03 (0.07) |
0.01 (0.02) |
0.02 (0.04) |
0.02 (0.02) |
Chromium_ppm (mean (SD)) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
Copper_ppm (mean (SD)) |
0.03 (0.05) |
0.02 (0.03) |
0.06 (0.08) |
0.02 (0.03) |
0.02 (0.04) |
0.03 (0.05) |
0.09 (0.12) |
Lead (mean (SD)) |
0.39 (0.66) |
0.41 (0.62) |
0.57 (0.86) |
0.42 (0.77) |
0.08 (0.09) |
0.34 (0.72) |
0.29 (0.25) |
wNitrate.NO3.. (mean (SD)) |
2.18 (2.43) |
2.81 (2.95) |
3.65 (3.09) |
1.36 (0.66) |
2.60 (3.08) |
1.14 (0.72) |
3.17 (4.56) |
Selenium (mean (SD)) |
0.21 (0.49) |
0.14 (0.50) |
0.08 (0.20) |
0.38 (0.45) |
0.58 (0.16) |
0.03 (0.61) |
0.34 (0.25) |
Aluminum_ppm (mean (SD)) |
0.08 (0.08) |
0.11 (0.08) |
0.02 (0.02) |
0.09 (0.07) |
0.01 (0.03) |
0.08 (0.08) |
0.01 (0.01) |
Chloride_ppm (mean (SD)) |
7.17 (5.45) |
8.12 (5.73) |
1.82 (4.64) |
9.40 (4.98) |
4.28 (5.04) |
6.40 (4.07) |
3.96 (5.89) |
Iron_ppm (mean (SD)) |
0.02 (0.04) |
0.02 (0.02) |
0.01 (0.01) |
0.03 (0.07) |
0.01 (0.02) |
0.03 (0.04) |
0.01 (0.00) |
Manganese_ppm (mean (SD)) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.01) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
Zinc_ppm (mean (SD)) |
0.06 (0.08) |
0.05 (0.08) |
0.04 (0.05) |
0.09 (0.11) |
0.01 (0.02) |
0.07 (0.06) |
0.05 (0.03) |
Source water quality table
n |
75 |
27 |
6 |
19 |
4 |
15 |
4 |
wFphM (mean (SD)) |
7.81 (0.37) |
7.71 (0.37) |
7.73 (0.36) |
7.94 (0.31) |
7.98 (0.52) |
7.78 (0.39) |
7.84 (0.39) |
wFtempM (mean (SD)) |
18.59 (5.81) |
23.88 (3.32) |
21.53 (2.46) |
12.14 (1.60) |
13.07 (1.60) |
18.06 (5.26) |
16.58 (0.93) |
wFcondM (mean (SD)) |
334.15 (222.61) |
332.77 (266.04) |
412.17 (153.90) |
324.01 (187.62) |
485.25 (145.27) |
247.60 (205.73) |
448.12 (204.06) |
bTC (mean (SD)) |
0.31 (0.46) |
0.11 (0.32) |
1.00 (0.00) |
0.11 (0.32) |
1.00 (0.00) |
0.27 (0.46) |
1.00 (0.00) |
wTCmpn_M (mean (SD)) |
95.54 (390.60) |
28.61 (148.14) |
884.67 (1136.90) |
0.05 (0.16) |
47.00 (66.68) |
4.44 (11.59) |
207.31 (95.39) |
bEC (mean (SD)) |
0.11 (0.31) |
0.00 (0.00) |
0.67 (0.52) |
0.00 (0.00) |
0.25 (0.50) |
0.00 (0.00) |
0.75 (0.50) |
wECmpn_M (mean (SD)) |
1.74 (9.40) |
0.00 (0.00) |
19.96 (29.44) |
0.00 (0.00) |
0.12 (0.25) |
0.00 (0.00) |
2.56 (2.17) |
Arsenic (mean (SD)) |
0.12 (0.23) |
0.06 (0.08) |
0.30 (0.55) |
0.10 (0.05) |
0.52 (0.58) |
0.06 (0.06) |
0.22 (0.28) |
Barium_ppm (mean (SD)) |
0.04 (0.04) |
0.03 (0.02) |
0.08 (0.07) |
0.03 (0.01) |
0.10 (0.07) |
0.03 (0.01) |
0.10 (0.06) |
Cadmium (mean (SD)) |
0.00 (0.02) |
0.00 (0.00) |
0.02 (0.04) |
0.00 (0.01) |
0.00 (0.01) |
0.00 (0.01) |
0.02 (0.04) |
Chromium_ppm (mean (SD)) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
Copper_ppm (mean (SD)) |
0.01 (0.02) |
0.01 (0.02) |
0.01 (0.01) |
0.01 (0.01) |
0.00 (0.00) |
0.01 (0.01) |
0.04 (0.08) |
Lead (mean (SD)) |
0.12 (0.40) |
0.09 (0.20) |
0.23 (0.34) |
0.07 (0.11) |
0.01 (0.04) |
0.03 (0.05) |
0.79 (1.59) |
wNitrate.NO3.. (mean (SD)) |
2.18 (2.21) |
2.80 (2.41) |
4.33 (4.32) |
1.42 (0.65) |
2.33 (2.92) |
1.16 (0.73) |
2.12 (1.94) |
Selenium (mean (SD)) |
0.21 (0.44) |
0.21 (0.47) |
0.17 (0.14) |
0.25 (0.39) |
0.34 (0.07) |
0.11 (0.62) |
0.22 (0.30) |
Aluminum_ppm (mean (SD)) |
0.07 (0.09) |
0.12 (0.11) |
0.02 (0.02) |
0.06 (0.05) |
0.01 (0.02) |
0.06 (0.07) |
0.02 (0.03) |
Chloride_ppm (mean (SD)) |
7.15 (5.51) |
8.29 (5.83) |
1.35 (4.48) |
9.20 (4.91) |
4.23 (4.98) |
6.39 (4.16) |
4.15 (6.24) |
Iron_ppm (mean (SD)) |
0.02 (0.04) |
0.02 (0.04) |
0.05 (0.08) |
0.02 (0.04) |
0.00 (0.00) |
0.02 (0.03) |
0.02 (0.03) |
Manganese_ppm (mean (SD)) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.01) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
Zinc_ppm (mean (SD)) |
0.01 (0.01) |
0.01 (0.01) |
0.01 (0.01) |
0.01 (0.01) |
0.00 (0.00) |
0.01 (0.01) |
0.02 (0.04) |
Water quality plots: subset to households in all rounds
Health outcome table
n |
65 |
18 |
49 |
16 |
35 |
14 |
High blood pressure (%) |
|
|
|
|
|
|
No |
31 (47.7) |
13 ( 72.2) |
27 (55.1) |
12 ( 75.0) |
15 (42.9) |
8 (57.1) |
Yes |
27 (41.5) |
4 ( 22.2) |
19 (38.8) |
4 ( 25.0) |
17 (48.6) |
6 (42.9) |
Yes, in the past |
5 ( 7.7) |
0 ( 0.0) |
1 ( 2.0) |
0 ( 0.0) |
2 ( 5.7) |
0 ( 0.0) |
NA |
2 ( 3.1) |
1 ( 5.6) |
2 ( 4.1) |
0 ( 0.0) |
1 ( 2.9) |
0 ( 0.0) |
Liver disease (%) |
|
|
|
|
|
|
No |
62 (95.4) |
17 ( 94.4) |
45 (91.8) |
16 (100.0) |
32 (91.4) |
13 (92.9) |
Yes |
3 ( 4.6) |
1 ( 5.6) |
4 ( 8.2) |
0 ( 0.0) |
3 ( 8.6) |
0 ( 0.0) |
NA |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
1 ( 7.1) |
Kidney disease (%) |
|
|
|
|
|
|
No |
57 (87.7) |
16 ( 88.9) |
45 (91.8) |
15 ( 93.8) |
31 (88.6) |
11 (78.6) |
Yes |
6 ( 9.2) |
1 ( 5.6) |
4 ( 8.2) |
1 ( 6.2) |
3 ( 8.6) |
2 (14.3) |
Yes, in the past |
2 ( 3.1) |
1 ( 5.6) |
0 ( 0.0) |
0 ( 0.0) |
1 ( 2.9) |
0 ( 0.0) |
NA |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
1 ( 7.1) |
Bladder disease (%) |
|
|
|
|
|
|
No |
62 (95.4) |
17 ( 94.4) |
47 (95.9) |
16 (100.0) |
33 (94.3) |
13 (92.9) |
Yes |
1 ( 1.5) |
0 ( 0.0) |
2 ( 4.1) |
0 ( 0.0) |
2 ( 5.7) |
1 ( 7.1) |
Yes, in the past |
1 ( 1.5) |
1 ( 5.6) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
NA |
1 ( 1.5) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
0 ( 0.0) |
Tobacco use (%) |
|
|
|
|
|
|
No |
34 (52.3) |
10 ( 55.6) |
27 (55.1) |
9 ( 56.2) |
18 (51.4) |
8 (57.1) |
Yes |
27 (41.5) |
5 ( 27.8) |
21 (42.9) |
7 ( 43.8) |
15 (42.9) |
5 (35.7) |
Yes, in the past |
4 ( 6.2) |
3 ( 16.7) |
1 ( 2.0) |
0 ( 0.0) |
2 ( 5.7) |
1 ( 7.1) |
Cough = Yes (%) |
27 (41.5) |
3 ( 16.7) |
19 (38.8) |
5 ( 31.2) |
14 (40.0) |
6 (42.9) |
Toothache (%) |
|
|
|
|
|
|
No |
56 (86.2) |
18 (100.0) |
43 (87.8) |
16 (100.0) |
32 (91.4) |
13 (92.9) |
Yes |
9 (13.8) |
0 ( 0.0) |
5 (10.2) |
0 ( 0.0) |
2 ( 5.7) |
1 ( 7.1) |
NA |
0 ( 0.0) |
0 ( 0.0) |
1 ( 2.0) |
0 ( 0.0) |
1 ( 2.9) |
0 ( 0.0) |
Diarrhea (%) |
|
|
|
|
|
|
No |
52 (80.0) |
18 (100.0) |
38 (77.6) |
14 ( 87.5) |
29 (82.9) |
10 (71.4) |
Yes |
8 (12.3) |
0 ( 0.0) |
9 (18.4) |
2 ( 12.5) |
6 (17.1) |
2 (14.3) |
NA |
5 ( 7.7) |
0 ( 0.0) |
2 ( 4.1) |
0 ( 0.0) |
0 ( 0.0) |
2 (14.3) |
E coli table
n |
65 |
18 |
49 |
16 |
35 |
14 |
|
|
No E. coli Detected in Source Water (mean (SD)) |
0.00 (0.00) |
0.61 (0.50) |
0.00 (0.00) |
0.31 (0.48) |
0.00 (0.00) |
0.79 (0.43) |
<0.001 |
|
Diarrhea (%) |
|
|
|
|
|
|
0.270 |
|
No |
52 (80.0) |
18 (100.0) |
38 (77.6) |
14 (87.5) |
29 (82.9) |
10 (71.4) |
|
|
Yes |
8 (12.3) |
0 ( 0.0) |
9 (18.4) |
2 (12.5) |
6 (17.1) |
2 (14.3) |
|
|
NA |
5 ( 7.7) |
0 ( 0.0) |
2 ( 4.1) |
0 ( 0.0) |
0 ( 0.0) |
2 (14.3) |
|
|
Pathogen incidence TMLE results
Adjusted TMLE results

Norovirus incidence results

Diarrhea outcome results

Supplimentary materials
Bottled water quality table
n |
44 |
16 |
3 |
12 |
3 |
8 |
2 |
wFphM (mean (SD)) |
6.87 (0.86) |
6.58 (0.76) |
6.90 (1.27) |
7.22 (0.66) |
8.16 (0.18) |
6.68 (0.91) |
7.12 (1.46) |
wFtempM (mean (SD)) |
17.55 (6.09) |
17.98 (7.34) |
18.48 (7.25) |
14.37 (3.77) |
20.27 (0.74) |
17.39 (5.69) |
23.80 (2.62) |
wFcondM (mean (SD)) |
115.26 (138.29) |
78.78 (104.24) |
100.75 (134.00) |
98.73 (89.34) |
323.50 (3.54) |
158.33 (219.20) |
107.20 (93.83) |
bTC (mean (SD)) |
0.02 (0.15) |
0.00 (0.00) |
0.33 (0.58) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
wTCmpn_M (mean (SD)) |
0.01 (0.08) |
0.00 (0.00) |
0.17 (0.29) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
bEC (mean (SD)) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
wECmpn_M (mean (SD)) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
Arsenic (mean (SD)) |
-0.03 (0.06) |
-0.06 (0.05) |
-0.10 (0.00) |
0.00 (0.03) |
0.09 (0.02) |
-0.01 (0.06) |
-0.01 (0.03) |
Barium_ppm (mean (SD)) |
0.01 (0.02) |
0.01 (0.02) |
0.01 (0.01) |
0.01 (0.02) |
0.02 (0.00) |
0.02 (0.03) |
0.01 (0.02) |
Cadmium (mean (SD)) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
-0.01 (0.00) |
0.00 (0.00) |
0.00 (0.01) |
-0.01 (0.00) |
Chromium_ppm (mean (SD)) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
Copper_ppm (mean (SD)) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
Lead (mean (SD)) |
-0.01 (0.01) |
0.00 (0.00) |
0.00 (0.00) |
-0.01 (0.02) |
-0.02 (0.01) |
-0.01 (0.01) |
-0.02 (0.00) |
wNitrate.NO3.. (mean (SD)) |
1.51 (1.87) |
2.69 (2.51) |
1.10 (0.79) |
0.66 (0.28) |
1.00 (0.14) |
0.69 (0.51) |
0.45 (0.07) |
Selenium (mean (SD)) |
0.07 (0.28) |
0.11 (0.34) |
0.03 (0.21) |
0.12 (0.07) |
0.35 (0.04) |
-0.11 (0.31) |
-0.06 (0.11) |
Aluminum_ppm (mean (SD)) |
0.01 (0.03) |
0.01 (0.03) |
0.00 (0.00) |
0.00 (0.00) |
0.06 (0.05) |
0.02 (0.05) |
0.00 (0.00) |
Chloride_ppm (mean (SD)) |
2.59 (4.19) |
1.40 (4.31) |
-0.80 (0.87) |
4.14 (4.57) |
6.71 (0.23) |
3.17 (3.65) |
3.76 (5.04) |
Iron_ppm (mean (SD)) |
0.00 (0.01) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.01 (0.00) |
0.01 (0.00) |
Manganese_ppm (mean (SD)) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
Zinc_ppm (mean (SD)) |
0.00 (0.01) |
0.01 (0.02) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |
0.00 (0.00) |