#To do:

From Tim: instead of log-MFI, do ratio to total IgG, then take the log

Balance tables

Table 1:
round nHH nInd strata
R1 33 83 Overall
R2 23 65 Overall
R3 19 49 Overall
R1 27 65 Utility Water
R1 6 18 Non-utility Water
R2 19 49 Utility Water
R2 4 16 Non-utility Water
R3 15 35 Utility Water
R3 4 14 Non-utility Water
R1 14 40 Bottled water
R1 3 9 Spring water
R1 13 25 Utility Water
R1 3 9 Well water
R2 9 27 Bottled water
R2 1 5 Spring water
R2 11 27 Utility Water
R2 2 6 Well water
R3 7 16 Bottled water
R3 2 9 Spring water
R3 8 19 Utility Water
R3 2 5 Well water
Table 1:
Overall Utility Water Non-utility Water
n 83 65 18
Head of household: female = Male (%) 16 (48.5) 12 (44.4) 4 ( 66.7)
Head of household: age (mean (SD)) 58.97 (14.54) 60.78 (13.77) 50.83 (16.40)
Head of household: education (%)
Community college or higher 28 (33.7) 20 (30.8) 8 ( 44.4)
High school graduate 42 (50.6) 32 (49.2) 10 ( 55.6)
Less than a high school education 13 (15.7) 13 (20.0) 0 ( 0.0)
Household members: female = Female (%) 46 (55.4) 37 (56.9) 9 ( 50.0)
Household members: age (mean (SD)) 40.99 (24.62) 43.08 (24.58) 33.44 (23.94)
Household members: ethnicity = White (%) 77 (92.8) 64 (98.5) 13 ( 72.2)
Household income (%)
<$15k 29 (34.9) 22 (33.8) 7 ( 38.9)
$15k-$20k 10 (12.0) 6 ( 9.2) 4 ( 22.2)
$20k-$25k 8 ( 9.6) 8 (12.3) 0 ( 0.0)
$25k-$30k 26 (31.3) 22 (33.8) 4 ( 22.2)
$35k-$40k 5 ( 6.0) 5 ( 7.7) 0 ( 0.0)
$40k-$45k 0 ( 0.0) 0 ( 0.0) 0 ( 0.0)
>$50k 5 ( 6.0) 2 ( 3.1) 3 ( 16.7)
Don’t want to say 0 ( 0.0) 0 ( 0.0) 0 ( 0.0)
Working toilet, sink, tub/shower (%)
Toilet & shower 6 ( 7.2) 6 ( 9.2) 0 ( 0.0)
Toilet & sink 4 ( 4.8) 4 ( 6.2) 0 ( 0.0)
Yes, all work 73 (88.0) 55 (84.6) 18 (100.0)
Sanitary sewer, septic, or straight pipe (%)
Septic tank & drainfield 36 (43.4) 18 (27.7) 18 (100.0)
Straight pipe 2 ( 2.4) 2 ( 3.1) 0 ( 0.0)
Utility sewer connection 45 (54.2) 45 (69.2) 0 ( 0.0)
Time to healthcare facility if minor issue (minutes) (mean (SD)) 14.76 (9.79) 13.15 (9.18) 20.56 (9.98)
Time to healthcare facility if major issue (minutes) (mean (SD)) 41.25 (27.28) 36.37 (22.69) 58.89 (35.09)
Table 1:
Overall R1 R2 R3
n 197 83 65 49
Head of household: female (%)
Female 23 (11.7) 17 (20.5) 0 ( 0.0) 6 (12.2)
Male 30 (15.2) 16 (19.3) 0 ( 0.0) 14 (28.6)
NA 144 (73.1) 50 (60.2) 65 (100.0) 29 (59.2)
Head of household: age (mean (SD)) 59.28 (14.84) 58.97 (14.54) NaN (NA) 59.80 (15.70)
Head of household: education (%)
Community college or higher 57 (28.9) 28 (33.7) 19 ( 29.2) 10 (20.4)
High school graduate 101 (51.3) 42 (50.6) 36 ( 55.4) 23 (46.9)
Less than a high school education 39 (19.8) 13 (15.7) 10 ( 15.4) 16 (32.7)
Household members: female = Female (%) 109 (55.3) 46 (55.4) 34 ( 52.3) 29 (59.2)
Household members: age (mean (SD)) 41.87 (24.13) 40.99 (24.62) 40.49 (24.16) 45.18 (23.44)
Household members: ethnicity = White (%) 182 (92.4) 77 (92.8) 57 ( 87.7) 48 (98.0)
Household income (%)
<$15k 42 (21.3) 29 (34.9) 0 ( 0.0) 13 (26.5)
$15k-$20k 25 (12.7) 10 (12.0) 0 ( 0.0) 15 (30.6)
$20k-$25k 18 ( 9.1) 8 ( 9.6) 0 ( 0.0) 10 (20.4)
$25k-$30k 31 (15.7) 26 (31.3) 0 ( 0.0) 5 (10.2)
$35k-$40k 5 ( 2.5) 5 ( 6.0) 0 ( 0.0) 0 ( 0.0)
$40k-$45k 2 ( 1.0) 0 ( 0.0) 0 ( 0.0) 2 ( 4.1)
>$50k 5 ( 2.5) 5 ( 6.0) 0 ( 0.0) 0 ( 0.0)
Don’t want to say 4 ( 2.0) 0 ( 0.0) 0 ( 0.0) 4 ( 8.2)
NA 65 (33.0) 0 ( 0.0) 65 (100.0) 0 ( 0.0)
Working toilet, sink, tub/shower (%)
Toilet & shower 16 ( 8.1) 6 ( 7.2) 8 ( 12.3) 2 ( 4.1)
Toilet & sink 4 ( 2.0) 4 ( 4.8) 0 ( 0.0) 0 ( 0.0)
Yes, all work 177 (89.8) 73 (88.0) 57 ( 87.7) 47 (95.9)
Sanitary sewer, septic, or straight pipe (%)
Other 2 ( 1.0) 0 ( 0.0) 0 ( 0.0) 2 ( 4.1)
Septic tank & drainfield 91 (46.2) 36 (43.4) 27 ( 41.5) 28 (57.1)
Septic tank but no drainfield 9 ( 4.6) 0 ( 0.0) 9 ( 13.8) 0 ( 0.0)
Straight pipe 8 ( 4.1) 2 ( 2.4) 4 ( 6.2) 2 ( 4.1)
Utility sewer connection 87 (44.2) 45 (54.2) 25 ( 38.5) 17 (34.7)
Time to healthcare facility if minor issue (minutes) (mean (SD)) 15.95 (10.24) 14.76 (9.79) 18.37 (9.55) 14.79 (11.51)
Time to healthcare facility if major issue (minutes) (mean (SD)) 43.25 (29.77) 41.25 (27.28) 45.74 (31.30) 43.53 (32.27)
Table 1:
Overall Utility Water:R1 Non-utility Water:R1 Utility Water:R2 Non-utility Water:R2 Utility Water:R3 Non-utility Water:R3
n 197 65 18 49 16 35 14
Head of household: female (%)
Female 23 (11.7) 15 (23.1) 2 ( 11.1) 0 ( 0.0) 0 ( 0.0) 6 (17.1) 0 ( 0.0)
Male 30 (15.2) 12 (18.5) 4 ( 22.2) 0 ( 0.0) 0 ( 0.0) 10 (28.6) 4 ( 28.6)
NA 144 (73.1) 38 (58.5) 12 ( 66.7) 49 (100.0) 16 (100.0) 19 (54.3) 10 ( 71.4)
Head of household: age (mean (SD)) 59.28 (14.84) 60.78 (13.77) 50.83 (16.40) NaN (NA) NaN (NA) 61.19 (15.58) 54.25 (17.19)
Head of household: education (%)
Community college or higher 57 (28.9) 20 (30.8) 8 ( 44.4) 13 ( 26.5) 6 ( 37.5) 5 (14.3) 5 ( 35.7)
High school graduate 101 (51.3) 32 (49.2) 10 ( 55.6) 26 ( 53.1) 10 ( 62.5) 14 (40.0) 9 ( 64.3)
Less than a high school education 39 (19.8) 13 (20.0) 0 ( 0.0) 10 ( 20.4) 0 ( 0.0) 16 (45.7) 0 ( 0.0)
Household members: female = Female (%) 109 (55.3) 37 (56.9) 9 ( 50.0) 28 ( 57.1) 6 ( 37.5) 21 (60.0) 8 ( 57.1)
Household members: age (mean (SD)) 41.87 (24.13) 43.08 (24.58) 33.44 (23.94) 42.94 (24.06) 33.00 (23.63) 48.49 (22.74) 36.93 (23.95)
Household members: ethnicity = White (%) 182 (92.4) 64 (98.5) 13 ( 72.2) 46 ( 93.9) 11 ( 68.8) 34 (97.1) 14 (100.0)
Household income (%)
<$15k 42 (21.3) 22 (33.8) 7 ( 38.9) 0 ( 0.0) 0 ( 0.0) 10 (28.6) 3 ( 21.4)
$15k-$20k 25 (12.7) 6 ( 9.2) 4 ( 22.2) 0 ( 0.0) 0 ( 0.0) 15 (42.9) 0 ( 0.0)
$20k-$25k 18 ( 9.1) 8 (12.3) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 5 (14.3) 5 ( 35.7)
$25k-$30k 31 (15.7) 22 (33.8) 4 ( 22.2) 0 ( 0.0) 0 ( 0.0) 5 (14.3) 0 ( 0.0)
$35k-$40k 5 ( 2.5) 5 ( 7.7) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0)
$40k-$45k 2 ( 1.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 2 ( 14.3)
>$50k 5 ( 2.5) 2 ( 3.1) 3 ( 16.7) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0)
Don’t want to say 4 ( 2.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 4 ( 28.6)
NA 65 (33.0) 0 ( 0.0) 0 ( 0.0) 49 (100.0) 16 (100.0) 0 ( 0.0) 0 ( 0.0)
Working toilet, sink, tub/shower (%)
Toilet & shower 16 ( 8.1) 6 ( 9.2) 0 ( 0.0) 8 ( 16.3) 0 ( 0.0) 2 ( 5.7) 0 ( 0.0)
Toilet & sink 4 ( 2.0) 4 ( 6.2) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0)
Yes, all work 177 (89.8) 55 (84.6) 18 (100.0) 41 ( 83.7) 16 (100.0) 33 (94.3) 14 (100.0)
Sanitary sewer, septic, or straight pipe (%)
Other 2 ( 1.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 2 ( 5.7) 0 ( 0.0)
Septic tank & drainfield 91 (46.2) 18 (27.7) 18 (100.0) 20 ( 40.8) 7 ( 43.8) 14 (40.0) 14 (100.0)
Septic tank but no drainfield 9 ( 4.6) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 9 ( 56.2) 0 ( 0.0) 0 ( 0.0)
Straight pipe 8 ( 4.1) 2 ( 3.1) 0 ( 0.0) 4 ( 8.2) 0 ( 0.0) 2 ( 5.7) 0 ( 0.0)
Utility sewer connection 87 (44.2) 45 (69.2) 0 ( 0.0) 25 ( 51.0) 0 ( 0.0) 17 (48.6) 0 ( 0.0)
Time to healthcare facility if minor issue (minutes) (mean (SD)) 15.95 (10.24) 13.15 (9.18) 20.56 (9.98) 16.44 (8.66) 24.06 (10.04) 16.03 (12.90) 11.86 (6.77)
Time to healthcare facility if major issue (minutes) (mean (SD)) 43.25 (29.77) 36.37 (22.69) 58.89 (35.09) 43.88 (33.47) 53.33 (19.46) 46.52 (35.59) 36.50 (22.17)

Water quality tables

Note 1) Nitrate_ppm is not in the raw data, so using wNitrate.NO3 instead 2) drop[ed] one sample not matched to a household (sample code “122299spring” - roadside spring)

Tap (Exposure) water quality table

Overall Utility H2O:R1 Well or Spring H2O:R1 Utility H2O:R2 Well or Spring H2O:R2 Utility H2O:R3 Well or Spring H2O:R3
n 75 27 6 19 4 15 4
wFphM (mean (SD)) 7.83 (0.37) 7.74 (0.38) 7.74 (0.35) 7.94 (0.33) 7.96 (0.54) 7.86 (0.39) 7.83 (0.43)
wFtempM (mean (SD)) 18.72 (4.79) 22.83 (2.11) 22.13 (1.34) 13.75 (2.83) 11.74 (5.88) 17.95 (2.65) 19.41 (2.91)
wFcondM (mean (SD)) 334.17 (218.52) 332.29 (265.20) 415.00 (156.77) 325.46 (188.26) 445.25 (60.41) 256.56 (204.87) 446.88 (195.37)
bTC (mean (SD)) 0.29 (0.46) 0.19 (0.40) 0.83 (0.41) 0.16 (0.37) 1.00 (0.00) 0.07 (0.26) 1.00 (0.00)
wTCmpn_M (mean (SD)) 65.74 (295.74) 15.90 (67.48) 514.38 (963.97) 0.13 (0.37) 113.74 (125.31) 34.76 (134.62) 109.07 (80.17)
bEC (mean (SD)) 0.07 (0.25) 0.00 (0.00) 0.33 (0.52) 0.00 (0.00) 0.25 (0.50) 0.00 (0.00) 0.50 (0.58)
wECmpn_M (mean (SD)) 0.92 (5.98) 0.00 (0.00) 10.17 (20.32) 0.00 (0.00) 0.76 (1.52) 0.00 (0.00) 1.30 (1.73)
Arsenic (mean (SD)) 0.14 (0.25) 0.07 (0.08) 0.30 (0.51) 0.13 (0.06) 0.63 (0.66) 0.06 (0.05) 0.21 (0.33)
Barium_ppm (mean (SD)) 0.04 (0.04) 0.03 (0.02) 0.07 (0.07) 0.03 (0.01) 0.11 (0.08) 0.03 (0.01) 0.10 (0.06)
Cadmium (mean (SD)) 0.02 (0.05) 0.01 (0.05) 0.02 (0.04) 0.03 (0.07) 0.01 (0.02) 0.02 (0.04) 0.02 (0.02)
Chromium_ppm (mean (SD)) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00)
Copper_ppm (mean (SD)) 0.03 (0.05) 0.02 (0.03) 0.06 (0.08) 0.02 (0.03) 0.02 (0.04) 0.03 (0.05) 0.09 (0.12)
Lead (mean (SD)) 0.39 (0.66) 0.41 (0.62) 0.57 (0.86) 0.42 (0.77) 0.08 (0.09) 0.34 (0.72) 0.29 (0.25)
wNitrate.NO3.. (mean (SD)) 2.18 (2.43) 2.81 (2.95) 3.65 (3.09) 1.36 (0.66) 2.60 (3.08) 1.14 (0.72) 3.17 (4.56)
Selenium (mean (SD)) 0.21 (0.49) 0.14 (0.50) 0.08 (0.20) 0.38 (0.45) 0.58 (0.16) 0.03 (0.61) 0.34 (0.25)
Aluminum_ppm (mean (SD)) 0.08 (0.08) 0.11 (0.08) 0.02 (0.02) 0.09 (0.07) 0.01 (0.03) 0.08 (0.08) 0.01 (0.01)
Chloride_ppm (mean (SD)) 7.17 (5.45) 8.12 (5.73) 1.82 (4.64) 9.40 (4.98) 4.28 (5.04) 6.40 (4.07) 3.96 (5.89)
Iron_ppm (mean (SD)) 0.02 (0.04) 0.02 (0.02) 0.01 (0.01) 0.03 (0.07) 0.01 (0.02) 0.03 (0.04) 0.01 (0.00)
Manganese_ppm (mean (SD)) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.01) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00)
Zinc_ppm (mean (SD)) 0.06 (0.08) 0.05 (0.08) 0.04 (0.05) 0.09 (0.11) 0.01 (0.02) 0.07 (0.06) 0.05 (0.03)

Source water quality table

Overall Utility H2O:R1 Well or Spring H2O:R1 Utility H2O:R2 Well or Spring H2O:R2 Utility H2O:R3 Well or Spring H2O:R3
n 75 27 6 19 4 15 4
wFphM (mean (SD)) 7.81 (0.37) 7.71 (0.37) 7.73 (0.36) 7.94 (0.31) 7.98 (0.52) 7.78 (0.39) 7.84 (0.39)
wFtempM (mean (SD)) 18.59 (5.81) 23.88 (3.32) 21.53 (2.46) 12.14 (1.60) 13.07 (1.60) 18.06 (5.26) 16.58 (0.93)
wFcondM (mean (SD)) 334.15 (222.61) 332.77 (266.04) 412.17 (153.90) 324.01 (187.62) 485.25 (145.27) 247.60 (205.73) 448.12 (204.06)
bTC (mean (SD)) 0.31 (0.46) 0.11 (0.32) 1.00 (0.00) 0.11 (0.32) 1.00 (0.00) 0.27 (0.46) 1.00 (0.00)
wTCmpn_M (mean (SD)) 95.54 (390.60) 28.61 (148.14) 884.67 (1136.90) 0.05 (0.16) 47.00 (66.68) 4.44 (11.59) 207.31 (95.39)
bEC (mean (SD)) 0.11 (0.31) 0.00 (0.00) 0.67 (0.52) 0.00 (0.00) 0.25 (0.50) 0.00 (0.00) 0.75 (0.50)
wECmpn_M (mean (SD)) 1.74 (9.40) 0.00 (0.00) 19.96 (29.44) 0.00 (0.00) 0.12 (0.25) 0.00 (0.00) 2.56 (2.17)
Arsenic (mean (SD)) 0.12 (0.23) 0.06 (0.08) 0.30 (0.55) 0.10 (0.05) 0.52 (0.58) 0.06 (0.06) 0.22 (0.28)
Barium_ppm (mean (SD)) 0.04 (0.04) 0.03 (0.02) 0.08 (0.07) 0.03 (0.01) 0.10 (0.07) 0.03 (0.01) 0.10 (0.06)
Cadmium (mean (SD)) 0.00 (0.02) 0.00 (0.00) 0.02 (0.04) 0.00 (0.01) 0.00 (0.01) 0.00 (0.01) 0.02 (0.04)
Chromium_ppm (mean (SD)) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00)
Copper_ppm (mean (SD)) 0.01 (0.02) 0.01 (0.02) 0.01 (0.01) 0.01 (0.01) 0.00 (0.00) 0.01 (0.01) 0.04 (0.08)
Lead (mean (SD)) 0.12 (0.40) 0.09 (0.20) 0.23 (0.34) 0.07 (0.11) 0.01 (0.04) 0.03 (0.05) 0.79 (1.59)
wNitrate.NO3.. (mean (SD)) 2.18 (2.21) 2.80 (2.41) 4.33 (4.32) 1.42 (0.65) 2.33 (2.92) 1.16 (0.73) 2.12 (1.94)
Selenium (mean (SD)) 0.21 (0.44) 0.21 (0.47) 0.17 (0.14) 0.25 (0.39) 0.34 (0.07) 0.11 (0.62) 0.22 (0.30)
Aluminum_ppm (mean (SD)) 0.07 (0.09) 0.12 (0.11) 0.02 (0.02) 0.06 (0.05) 0.01 (0.02) 0.06 (0.07) 0.02 (0.03)
Chloride_ppm (mean (SD)) 7.15 (5.51) 8.29 (5.83) 1.35 (4.48) 9.20 (4.91) 4.23 (4.98) 6.39 (4.16) 4.15 (6.24)
Iron_ppm (mean (SD)) 0.02 (0.04) 0.02 (0.04) 0.05 (0.08) 0.02 (0.04) 0.00 (0.00) 0.02 (0.03) 0.02 (0.03)
Manganese_ppm (mean (SD)) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.01) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00)
Zinc_ppm (mean (SD)) 0.01 (0.01) 0.01 (0.01) 0.01 (0.01) 0.01 (0.01) 0.00 (0.00) 0.01 (0.01) 0.02 (0.04)

Water quality plots

\label{fig:figs}Boxplots of concentrations and log10 transformed concentrations for selected water quality parameters from source water samples (tap after 5-min flush) by household's primary water source.

Boxplots of concentrations and log10 transformed concentrations for selected water quality parameters from source water samples (tap after 5-min flush) by household’s primary water source.

\label{fig:figs}Mean concentrations for selected water quality parameters measured in utility-supplied source water samples (tap after 5-min flush) collected from study households and displayed based on household-level use of tap or bottled water for drinking.

Mean concentrations for selected water quality parameters measured in utility-supplied source water samples (tap after 5-min flush) collected from study households and displayed based on household-level use of tap or bottled water for drinking.

Water quality plots: subset to households in all rounds

\label{fig:figs} Sens1

Sens1

\label{fig:figs} Sens2

Sens2

Health outcome table

Utility Water:R1 Non-utility Water:R1 Utility Water:R2 Non-utility Water:R2 Utility Water:R3 Non-utility Water:R3
n 65 18 49 16 35 14
High blood pressure (%)
No 31 (47.7) 13 ( 72.2) 27 (55.1) 12 ( 75.0) 15 (42.9) 8 (57.1)
Yes 27 (41.5) 4 ( 22.2) 19 (38.8) 4 ( 25.0) 17 (48.6) 6 (42.9)
Yes, in the past 5 ( 7.7) 0 ( 0.0) 1 ( 2.0) 0 ( 0.0) 2 ( 5.7) 0 ( 0.0)
NA 2 ( 3.1) 1 ( 5.6) 2 ( 4.1) 0 ( 0.0) 1 ( 2.9) 0 ( 0.0)
Liver disease (%)
No 62 (95.4) 17 ( 94.4) 45 (91.8) 16 (100.0) 32 (91.4) 13 (92.9)
Yes 3 ( 4.6) 1 ( 5.6) 4 ( 8.2) 0 ( 0.0) 3 ( 8.6) 0 ( 0.0)
NA 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 1 ( 7.1)
Kidney disease (%)
No 57 (87.7) 16 ( 88.9) 45 (91.8) 15 ( 93.8) 31 (88.6) 11 (78.6)
Yes 6 ( 9.2) 1 ( 5.6) 4 ( 8.2) 1 ( 6.2) 3 ( 8.6) 2 (14.3)
Yes, in the past 2 ( 3.1) 1 ( 5.6) 0 ( 0.0) 0 ( 0.0) 1 ( 2.9) 0 ( 0.0)
NA 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 1 ( 7.1)
Bladder disease (%)
No 62 (95.4) 17 ( 94.4) 47 (95.9) 16 (100.0) 33 (94.3) 13 (92.9)
Yes 1 ( 1.5) 0 ( 0.0) 2 ( 4.1) 0 ( 0.0) 2 ( 5.7) 1 ( 7.1)
Yes, in the past 1 ( 1.5) 1 ( 5.6) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0)
NA 1 ( 1.5) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0) 0 ( 0.0)
Tobacco use (%)
No 34 (52.3) 10 ( 55.6) 27 (55.1) 9 ( 56.2) 18 (51.4) 8 (57.1)
Yes 27 (41.5) 5 ( 27.8) 21 (42.9) 7 ( 43.8) 15 (42.9) 5 (35.7)
Yes, in the past 4 ( 6.2) 3 ( 16.7) 1 ( 2.0) 0 ( 0.0) 2 ( 5.7) 1 ( 7.1)
Cough = Yes (%) 27 (41.5) 3 ( 16.7) 19 (38.8) 5 ( 31.2) 14 (40.0) 6 (42.9)
Toothache (%)
No 56 (86.2) 18 (100.0) 43 (87.8) 16 (100.0) 32 (91.4) 13 (92.9)
Yes 9 (13.8) 0 ( 0.0) 5 (10.2) 0 ( 0.0) 2 ( 5.7) 1 ( 7.1)
NA 0 ( 0.0) 0 ( 0.0) 1 ( 2.0) 0 ( 0.0) 1 ( 2.9) 0 ( 0.0)
Diarrhea (%)
No 52 (80.0) 18 (100.0) 38 (77.6) 14 ( 87.5) 29 (82.9) 10 (71.4)
Yes 8 (12.3) 0 ( 0.0) 9 (18.4) 2 ( 12.5) 6 (17.1) 2 (14.3)
NA 5 ( 7.7) 0 ( 0.0) 2 ( 4.1) 0 ( 0.0) 0 ( 0.0) 2 (14.3)

E coli table

Utility Water:R1 Non-utility Water:R1 Utility Water:R2 Non-utility Water:R2 Utility Water:R3 Non-utility Water:R3 p test
n 65 18 49 16 35 14
No E. coli Detected in Source Water (mean (SD)) 0.00 (0.00) 0.61 (0.50) 0.00 (0.00) 0.31 (0.48) 0.00 (0.00) 0.79 (0.43) <0.001
Diarrhea (%) 0.270
No 52 (80.0) 18 (100.0) 38 (77.6) 14 (87.5) 29 (82.9) 10 (71.4)
Yes 8 (12.3) 0 ( 0.0) 9 (18.4) 2 (12.5) 6 (17.1) 2 (14.3)
NA 5 ( 7.7) 0 ( 0.0) 2 ( 4.1) 0 ( 0.0) 0 ( 0.0) 2 (14.3)

Antigen classification

Pathogen incidence TMLE results

Adjusted TMLE results

Norovirus incidence results

Diarrhea outcome results

Supplimentary materials

Bottled water quality table

Overall Utility H2O:R1 Well or Spring H2O:R1 Utility H2O:R2 Well or Spring H2O:R2 Utility H2O:R3 Well or Spring H2O:R3
n 44 16 3 12 3 8 2
wFphM (mean (SD)) 6.87 (0.86) 6.58 (0.76) 6.90 (1.27) 7.22 (0.66) 8.16 (0.18) 6.68 (0.91) 7.12 (1.46)
wFtempM (mean (SD)) 17.55 (6.09) 17.98 (7.34) 18.48 (7.25) 14.37 (3.77) 20.27 (0.74) 17.39 (5.69) 23.80 (2.62)
wFcondM (mean (SD)) 115.26 (138.29) 78.78 (104.24) 100.75 (134.00) 98.73 (89.34) 323.50 (3.54) 158.33 (219.20) 107.20 (93.83)
bTC (mean (SD)) 0.02 (0.15) 0.00 (0.00) 0.33 (0.58) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00)
wTCmpn_M (mean (SD)) 0.01 (0.08) 0.00 (0.00) 0.17 (0.29) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00)
bEC (mean (SD)) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00)
wECmpn_M (mean (SD)) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00)
Arsenic (mean (SD)) -0.03 (0.06) -0.06 (0.05) -0.10 (0.00) 0.00 (0.03) 0.09 (0.02) -0.01 (0.06) -0.01 (0.03)
Barium_ppm (mean (SD)) 0.01 (0.02) 0.01 (0.02) 0.01 (0.01) 0.01 (0.02) 0.02 (0.00) 0.02 (0.03) 0.01 (0.02)
Cadmium (mean (SD)) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) -0.01 (0.00) 0.00 (0.00) 0.00 (0.01) -0.01 (0.00)
Chromium_ppm (mean (SD)) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00)
Copper_ppm (mean (SD)) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00)
Lead (mean (SD)) -0.01 (0.01) 0.00 (0.00) 0.00 (0.00) -0.01 (0.02) -0.02 (0.01) -0.01 (0.01) -0.02 (0.00)
wNitrate.NO3.. (mean (SD)) 1.51 (1.87) 2.69 (2.51) 1.10 (0.79) 0.66 (0.28) 1.00 (0.14) 0.69 (0.51) 0.45 (0.07)
Selenium (mean (SD)) 0.07 (0.28) 0.11 (0.34) 0.03 (0.21) 0.12 (0.07) 0.35 (0.04) -0.11 (0.31) -0.06 (0.11)
Aluminum_ppm (mean (SD)) 0.01 (0.03) 0.01 (0.03) 0.00 (0.00) 0.00 (0.00) 0.06 (0.05) 0.02 (0.05) 0.00 (0.00)
Chloride_ppm (mean (SD)) 2.59 (4.19) 1.40 (4.31) -0.80 (0.87) 4.14 (4.57) 6.71 (0.23) 3.17 (3.65) 3.76 (5.04)
Iron_ppm (mean (SD)) 0.00 (0.01) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.01 (0.00) 0.01 (0.00)
Manganese_ppm (mean (SD)) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00)
Zinc_ppm (mean (SD)) 0.00 (0.01) 0.01 (0.02) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00)
\label{fig:figs}Boxplots of concentrations and log10 transformed concentrations for selected water quality parameters from source water samples (tap after 5-min flush) by household's primary water source (stratifying well and spring water).

Boxplots of concentrations and log10 transformed concentrations for selected water quality parameters from source water samples (tap after 5-min flush) by household’s primary water source (stratifying well and spring water).