Table 1

0
(N=118)		 1
(N=159)		 Overall
(N=277)
Gender
Female 54 (45.8%) 63 (39.6%) 117 (42.2%)
Male 64 (54.2%) 96 (60.4%) 160 (57.8%)
Age
Mean (SD) 68.1 (13.2) 70.9 (11.2) 69.7 (12.2)
Median [Q1,Q3] 69.0 [58.3,78.0] 71.0 [65.5,79.0] 70.0 [62.0,78.0]
Race_Group
White 66 (55.9%) 107 (67.3%) 173 (62.5%)
Asian 5 (4.2%) 11 (6.9%) 16 (5.8%)
Black 28 (23.7%) 24 (15.1%) 52 (18.8%)
Other 19 (16.1%) 17 (10.7%) 36 (13.0%)
LOS
Mean (SD) 11.2 (10.6) 8.50 (6.32) 9.64 (8.50)
Median [Q1,Q3] 7.00 [4.25,13.5] 7.00 [4.00,10.5] 7.00 [4.00,11.0]
HTN
N 2 (1.7%) 5 (3.1%) 7 (2.5%)
Y 116 (98.3%) 154 (96.9%) 270 (97.5%)
DM
N 24 (20.3%) 41 (25.8%) 65 (23.5%)
Y 94 (79.7%) 118 (74.2%) 212 (76.5%)
CAD
N 15 (12.7%) 20 (12.6%) 35 (12.6%)
Y 103 (87.3%) 139 (87.4%) 242 (87.4%)
Hgb
Mean (SD) 9.94 (1.50) 10.1 (1.72) 10.0 (1.63)
Median [Q1,Q3] 9.80 [8.93,10.8] 10.0 [8.90,11.3] 10.0 [8.90,11.1]
HCT_admit
Mean (SD) 31.4 (4.84) 32.0 (5.58) 31.7 (5.28)
Median [Q1,Q3] 31.2 [28.1,34.4] 31.5 [28.1,35.4] 31.3 [28.1,35.2]
HCT_discharge
Mean (SD) 29.2 (3.94) 30.7 (4.56) 30.1 (4.36)
Median [Q1,Q3] 29.0 [26.6,31.7] 30.4 [27.5,33.2] 29.8 [27.1,32.4]
Iron
Mean (SD) 54.4 (27.4) 51.4 (32.6) 52.5 (30.7)
Median [Q1,Q3] 49.0 [37.5,67.0] 43.5 [31.0,60.0] 45.0 [32.3,63.5]
Missing 35 (29.7%) 19 (11.9%) 54 (19.5%)
Ferritin
Mean (SD) 985 (769) 1310 (3970) 1190 (3200)
Median [Q1,Q3] 785 [326,1430] 821 [439,1320] 810 [370,1380]
Missing 39 (33.1%) 22 (13.8%) 61 (22.0%)
TIBC
Mean (SD) 195 (50.8) 196 (63.1) 195 (58.7)
Median [Q1,Q3] 188 [162,224] 190 [159,225] 189 [161,225]
Missing 38 (32.2%) 24 (15.1%) 62 (22.4%)
TSAT
Mean (SD) 21.9 (8.52) 36.5 (48.5) 35.0 (46.2)
Median [Q1,Q3] 18.5 [16.5,28.0] 25.0 [17.5,34.0] 23.0 [17.0,34.0]
Missing 110 (93.2%) 88 (55.3%) 198 (71.5%)
NT_proBNP
Mean (SD) 43100 (34800) 46600 (48400) 45100 (43300)
Median [Q1,Q3] 35200 [15900,70000] 31600 [14300,58400] 32700 [14600,64900]
Missing 14 (11.9%) 8 (5.0%) 22 (7.9%)
troponin_T
Mean (SD) 0.388 (0.649) 1.03 (7.15) 0.770 (5.51)
Median [Q1,Q3] 0.160 [0.0600,0.330] 0.105 [0.0600,0.233] 0.120 [0.0600,0.260]
Missing 57 (48.3%) 71 (44.7%) 128 (46.2%)
hTS
Mean (SD) 267 (381) 213 (324) 236 (348)
Median [Q1,Q3] 168 [75.5,275] 128 [81.8,253] 145 [78.5,270]
Missing 72 (61.0%) 95 (59.7%) 167 (60.3%)
RVSP
Mean (SD) 45.6 (16.4) 49.9 (13.1) 47.9 (14.8)
Median [Q1,Q3] 44.0 [34.8,54.9] 48.0 [41.0,56.8] 46.0 [39.0,55.0]
Missing 33 (28.0%) 61 (38.4%) 94 (33.9%)
EF
Mean (SD) 48.4 (14.5) 55.2 (16.5) 52.3 (16.0)
Median [Q1,Q3] 50.0 [40.0,60.0] 59.0 [46.0,67.0] 55.0 [40.0,65.0]
Missing 21 (17.8%) 28 (17.6%) 49 (17.7%)
LA_index
Mean (SD) 52.1 (20.3) 47.0 (11.6) 47.7 (13.2)
Median [Q1,Q3] 44.7 [38.8,54.6] 46.3 [40.2,53.2] 46.2 [40.2,53.4]
Missing 99 (83.9%) 43 (27.0%) 142 (51.3%)
UF_rate
Mean (SD) 10.3 (6.01) 9.85 (4.14) 10.1 (5.02)
Median [Q1,Q3] 9.52 [6.17,12.8] 9.46 [6.84,12.7] 9.46 [6.77,12.7]
EDW
Mean (SD) 76.9 (22.6) 78.0 (21.6) 77.5 (22.0)
Median [Q1,Q3] 74.9 [60.0,87.3] 72.3 [64.7,92.4] 74.3 [62.8,89.3]
Missing 0 (0%) 1 (0.6%) 1 (0.4%)
admit_Weight
Mean (SD) 80.7 (22.9) 82.3 (22.5) 81.6 (22.6)
Median [Q1,Q3] 77.7 [64.0,90.2] 77.1 [67.8,97.1] 77.4 [65.9,93.2]
Missing 1 (0.8%) 0 (0%) 1 (0.4%)
HF_score
Mean (SD) 2.16 (0.837) 1.91 (0.810) 2.01 (0.830)
Median [Q1,Q3] 2.00 [1.00,3.00] 2.00 [1.00,3.00] 2.00 [1.00,3.00]
Dialysis_Vintage
Mean (SD) 3.35 (4.55) 3.40 (3.41) 3.38 (3.93)
Median [Q1,Q3] 2.00 [1.00,4.00] 2.00 [1.00,4.00] 2.00 [1.00,4.00]
Access_type
AVF 88 (74.6%) 93 (58.5%) 181 (65.3%)
AVG 7 (5.9%) 23 (14.5%) 30 (10.8%)
TDC 23 (19.5%) 43 (27.0%) 66 (23.8%)
decongestion_time_days
Mean (SD) 2.70 (3.21) 1.50 (1.80) 2.01 (2.56)
Median [Q1,Q3] 2.00 [0.250,3.75] 1.00 [0,2.00] 2.00 [0,3.00]
type_of_oxygen
Bipap to RA 0 (0%) 1 (0.6%) 1 (0.4%)
CPAP to RA 0 (0%) 1 (0.6%) 1 (0.4%)
Intubated to RA 0 (0%) 2 (1.3%) 2 (0.7%)
Intube to RA 2 (1.7%) 0 (0%) 2 (0.7%)
NC to Baseline 2 (1.7%) 0 (0%) 2 (0.7%)
NC to baseline NC 2 (1.7%) 15 (9.4%) 17 (6.1%)
NC to NC 0 (0%) 1 (0.6%) 1 (0.4%)
NC to RA 77 (65.3%) 79 (49.7%) 156 (56.3%)
NINV to baseline NC 1 (0.8%) 0 (0%) 1 (0.4%)
NINV to RA 3 (2.5%) 0 (0%) 3 (1.1%)
NRB to NC 0 (0%) 1 (0.6%) 1 (0.4%)
NRB to RA 0 (0%) 3 (1.9%) 3 (1.1%)
RA 31 (26.3%) 55 (34.6%) 86 (31.0%)
Vent to RA 0 (0%) 1 (0.6%) 1 (0.4%)
n_90
Mean (SD) 0.847 (0.975) 0.497 (0.778) 0.646 (0.883)
Median [Q1,Q3] 1.00 [0,1.00] 0 [0,1.00] 0 [0,1.00]
n_180
Mean (SD) 1.36 (1.63) 0.736 (1.03) 1.00 (1.35)
Median [Q1,Q3] 1.00 [0,2.00] 0 [0,1.00] 1.00 [0,1.00]

Balance check before

## Balance Measures
##                     Type  M.0.Un SD.0.Un  M.1.Un SD.1.Un Diff.Un
## Age              Contin. 68.0508 13.2277 70.8868 11.2227  0.2312
## Race_Group_White  Binary  0.5593       .  0.6730       .  0.1136
## Race_Group_Asian  Binary  0.0424       .  0.0692       .  0.0268
## Race_Group_Black  Binary  0.2373       .  0.1509       . -0.0863
## Race_Group_Other  Binary  0.1610       .  0.1069       . -0.0541
## Gender_Male       Binary  0.5424       .  0.6038       .  0.0614
## CAD_Y             Binary  0.8729       .  0.8742       .  0.0013
## HTN_Y             Binary  0.9831       .  0.9686       . -0.0145
## DM_Y              Binary  0.7966       .  0.7421       . -0.0545
## HF_score         Contin.  2.1610  0.8369  1.9057  0.8097 -0.3101
## Dialysis_Vintage Contin.  3.3475  4.5524  3.3962  3.4089  0.0121
## Access_type_AVF   Binary  0.7458       .  0.5849       . -0.1609
## Access_type_AVG   Binary  0.0593       .  0.1447       .  0.0853
## Access_type_TDC   Binary  0.1949       .  0.2704       .  0.0755
## Location_HH       Binary  0.2966       .  0.1069       . -0.1897
## 
## Sample sizes
##     Control Treated
## All     118     159

Balance check after

## Balance Measures
##                     Type M.0.Adj SD.0.Adj M.1.Adj SD.1.Adj Diff.Adj
## Age              Contin. 69.5304  12.2024 68.9485  12.9026  -0.0474
## Race_Group_White  Binary  0.6114        .  0.6259        .   0.0146
## Race_Group_Asian  Binary  0.0413        .  0.0588        .   0.0175
## Race_Group_Black  Binary  0.2111        .  0.1871        .  -0.0240
## Race_Group_Other  Binary  0.1362        .  0.1281        .  -0.0080
## Gender_Male       Binary  0.5675        .  0.5864        .   0.0188
## CAD_Y             Binary  0.8782        .  0.8742        .  -0.0040
## HTN_Y             Binary  0.9837        .  0.9699        .  -0.0138
## DM_Y              Binary  0.7709        .  0.7721        .   0.0012
## HF_score         Contin.  2.0611   0.8458  2.0142   0.8340  -0.0569
## Dialysis_Vintage Contin.  3.9764   6.3354  3.2970   3.4354  -0.1689
## Access_type_AVF   Binary  0.7248        .  0.6241        .  -0.1007
## Access_type_AVG   Binary  0.0661        .  0.1151        .   0.0490
## Access_type_TDC   Binary  0.2091        .  0.2609        .   0.0518
## Location_HH       Binary  0.2050        .  0.1584        .  -0.0465
## 
## Effective sample sizes
##            Control Treated
## Unadjusted  118.    159.  
## Adjusted     98.12  131.37

Univariate linear regression outcome los

outcome los
Characteristic N Beta 95% CI1 p-value
group 529


    BWH
— —
    MGH
-2.1 -4.2, -0.06 0.044
Age 529 -0.01 -0.09, 0.07 0.842
Gender 529


    Female
— —
    Male
1.7 -0.36, 3.8 0.107
Race_Group 529


    White
— —
    Asian
-5.0 -9.7, -0.29 0.038
    Black
-3.4 -6.0, -0.77 0.012
    Other
-2.9 -5.9, 0.22 0.070
HTN 529


    N
— —
    Y
-5.5 -12, 1.3 0.114
DM 529


    N
— —
    Y
2.3 -0.11, 4.8 0.062
CAD 529


    N
— —
    Y
4.5 1.4, 7.6 0.005
Dialysis_Vintage 529 0.11 -0.10, 0.31 0.308
HF_score 529 1.5 0.30, 2.7 0.016
weight.ATE 529 0.29 -0.55, 1.1 0.504
1 CI = Confidence Interval

Univariate linear regression outcome log_los

outcome log_los
Characteristic N Beta 95% CI1 p-value
group 529


    BWH
— —
    MGH
-8.81 -23.71, 8.99 0.311
Age 529 0.00 -0.71, 0.72 0.995
Gender 529


    Female
— —
    Male
15.92 -3.17, 38.77 0.109
Race_Group 529


    White
— —
    Asian
-34.71 -56.63, -1.73 0.042
    Black
-23.48 -39.03, -3.97 0.022
    Other
-20.21 -38.91, 4.22 0.099
HTN 529


    N
— —
    Y
-32.71 -62.71, 21.42 0.189
DM 529


    N
— —
    Y
34.70 9.21, 66.13 0.006
CAD 529


    N
— —
    Y
51.64 16.15, 97.98 0.002
Dialysis_Vintage 529 1.10 -0.66, 2.90 0.224
HF_score 529 12.96 1.62, 25.57 0.025
weight.ATE 529 2.04 -5.14, 9.75 0.588
1 CI = Confidence Interval

Multivariate linear regression los: age gender race

outcome los
Characteristic N Beta 95% CI1 p-value
group



    BWH 260 — —
    MGH 268 -2.2 -4.2, -0.16 0.035
Age 529 -0.03 -0.12, 0.05 0.455
Gender



    Female 223 — —
    Male 305 1.4 -0.70, 3.5 0.192
Race_Group



    White 327 — —
    Asian 26 -4.6 -9.3, 0.12 0.057
    Black 105 -3.7 -6.4, -1.0 0.008
    Other 69 -2.4 -5.6, 0.71 0.130
1 CI = Confidence Interval

Multivariate linear regression log_los : age gender race

outcome log_los
Characteristic N Beta 95% CI1 p-value
group



    BWH 260 — —
    MGH 268 -9.22 -23.92, 8.32 0.284
Age 529 -0.16 -0.90, 0.59 0.677
Gender



    Female 223 — —
    Male 305 13.21 -5.84, 36.11 0.188
Race_Group



    White 327 — —
    Asian 26 -33.26 -55.76, 0.69 0.055
    Black 105 -24.56 -40.50, -4.35 0.021
    Other 69 -16.94 -36.97, 9.46 0.189
1 CI = Confidence Interval

Multivariate linear regression los ： group+ Age+Gender+Race_Group+HTN+DM+CAD+Dialysis_Vintage+HF_score

outcome los
Characteristic N Beta 95% CI1 p-value
group



    BWH 260 — —
    MGH 268 -2.0 -4.0, -0.06 0.045
Age 529 -0.05 -0.14, 0.03 0.209
Gender



    Female 223 — —
    Male 305 0.72 -1.4, 2.8 0.503
Race_Group



    White 327 — —
    Asian 26 -4.1 -8.7, 0.55 0.085
    Black 105 -3.0 -5.7, -0.34 0.028
    Other 69 -2.6 -5.7, 0.59 0.112
HTN



    N 12 — —
    Y 516 -4.8 -11, 1.8 0.155
DM



    N 120 — —
    Y 408 2.2 -0.37, 4.8 0.094
CAD



    N 65 — —
    Y 463 3.0 -0.23, 6.3 0.070
Dialysis_Vintage 529 0.18 -0.02, 0.39 0.085
HF_score 529 1.5 0.29, 2.7 0.016
1 CI = Confidence Interval

Multivariate linear regression log_los ： group+ Age+Gender+Race_Group+HTN+DM+CAD+Dialysis_Vintage+HF_score

outcome log_los
Characteristic N Beta 95% CI1 p-value
group



    BWH 260 — —
    MGH 268 -0.08 -0.25, 0.09 0.360
Age 529 0.00 -0.01, 0.00 0.390
Gender



    Female 223 — —
    Male 305 0.06 -0.13, 0.24 0.547
Race_Group



    White 327 — —
    Asian 26 -0.36 -0.76, 0.04 0.083
    Black 105 -0.22 -0.46, 0.01 0.062
    Other 69 -0.22 -0.49, 0.06 0.121
HTN



    N 12 — —
    Y 516 -0.34 -0.92, 0.23 0.239
DM



    N 120 — —
    Y 408 0.31 0.08, 0.53 0.008
CAD



    N 65 — —
    Y 463 0.26 -0.03, 0.54 0.076
Dialysis_Vintage 529 0.02 0.00, 0.04 0.025
HF_score 529 0.12 0.02, 0.23 0.022
1 CI = Confidence Interval

90 days poisson regression: group

Characteristic N IRR1 95% CI1 p-value
group



    BWH 260 — —
    MGH 268 0.64 0.51, 0.79 <0.001
1 IRR = Incidence Rate Ratio, CI = Confidence Interval

90 days poisson regression: group Age Gender Race_Group

Characteristic N IRR1 95% CI1 p-value
group



    BWH 260 — —
    MGH 268 0.63 0.51, 0.78 <0.001
Age 529 0.99 0.98, 1.00 0.010
Gender



    Female 223 — —
    Male 305 1.23 0.99, 1.54 0.068
Race_Group



    White 327 — —
    Asian 26 0.96 0.53, 1.61 0.900
    Black 105 1.37 1.05, 1.77 0.018
    Other 69 1.32 0.96, 1.81 0.083
1 IRR = Incidence Rate Ratio, CI = Confidence Interval

90 days poisson regression： group+ Age+Gender+Race_Group+HTN+DM+CAD+Dialysis_Vintage+HF_score

Characteristic N IRR1 95% CI1 p-value
group



    BWH 260 — —
    MGH 268 0.61 0.49, 0.76 <0.001
Age 529 0.99 0.98, 1.00 0.032
Gender



    Female 223 — —
    Male 305 1.29 1.03, 1.63 0.031
Race_Group



    White 327 — —
    Asian 26 0.93 0.51, 1.56 0.810
    Black 105 1.34 1.02, 1.74 0.031
    Other 69 1.32 0.95, 1.81 0.091
HTN



    N 12 — —
    Y 516 0.89 0.46, 2.03 0.760
DM



    N 120 — —
    Y 408 0.98 0.74, 1.30 0.864
CAD



    N 65 — —
    Y 463 0.85 0.61, 1.21 0.359
Dialysis_Vintage 529 0.94 0.90, 0.97 <0.001
HF_score 529 0.89 0.79, 1.02 0.085
1 IRR = Incidence Rate Ratio, CI = Confidence Interval

180 days poisson regression: group

Characteristic N IRR1 95% CI1 p-value
group



    BWH 260 — —
    MGH 268 0.58 0.49, 0.69 <0.001
1 IRR = Incidence Rate Ratio, CI = Confidence Interval

180 days poisson regression： Age Gender Race_Group

Characteristic N IRR1 95% CI1 p-value
group



    BWH 260 — —
    MGH 268 0.58 0.49, 0.69 <0.001
Age 529 0.99 0.98, 1.00 <0.001
Gender



    Female 223 — —
    Male 305 0.99 0.83, 1.18 0.889
Race_Group



    White 327 — —
    Asian 26 1.10 0.71, 1.63 0.660
    Black 105 1.25 1.01, 1.54 0.040
    Other 69 1.19 0.92, 1.53 0.178
1 IRR = Incidence Rate Ratio, CI = Confidence Interval

180 days poisson regression： group+ Age+Gender+Race_Group+HTN+DM+CAD+Dialysis_Vintage+HF_score

Characteristic N IRR1 95% CI1 p-value
group



    BWH 260 — —
    MGH 268 0.57 0.48, 0.68 <0.001
Age 529 0.99 0.98, 1.00 0.004
Gender



    Female 223 — —
    Male 305 1.03 0.86, 1.24 0.723
Race_Group



    White 327 — —
    Asian 26 1.06 0.68, 1.57 0.780
    Black 105 1.23 0.99, 1.53 0.058
    Other 69 1.22 0.94, 1.58 0.135
HTN



    N 12 — —
    Y 516 0.71 0.43, 1.24 0.190
DM



    N 120 — —
    Y 408 0.89 0.71, 1.11 0.296
CAD



    N 65 — —
    Y 463 0.91 0.70, 1.21 0.520
Dialysis_Vintage 529 0.93 0.90, 0.95 <0.001
HF_score 529 0.88 0.80, 0.98 0.017
1 IRR = Incidence Rate Ratio, CI = Confidence Interval

Univariate logistic regression outcome Binary Outcome is 1 or more versus 0: more_vs_zero_90days

Characteristic N OR1 95% CI1 p-value
group 529


    BWH
— —
    MGH
0.48 0.34, 0.68 <0.001
Age 529 0.99 0.97, 1.00 0.037
Gender 529


    Female
— —
    Male
1.15 0.81, 1.62 0.434
Race_Group 529


    White
— —
    Asian
0.78 0.34, 1.74 0.554
    Black
1.27 0.82, 1.97 0.289
    Other
1.00 0.59, 1.67 0.985
HTN 529


    N
— —
    Y
1.22 0.39, 4.07 0.734
DM 529


    N
— —
    Y
1.04 0.69, 1.57 0.844
CAD 529


    N
— —
    Y
0.77 0.46, 1.30 0.334
Dialysis_Vintage 529 0.92 0.87, 0.96 0.001
HF_score 529 0.88 0.72, 1.08 0.221
weight.ATE 529 1.05 0.91, 1.21 0.506
1 OR = Odds Ratio, CI = Confidence Interval

Multivariate logistic regression outcome Binary Outcome is 1 or more versus: 0 more_vs_zero_90days

Characteristic N OR1 95% CI1 p-value
group



    BWH 260 — —
    MGH 268 0.47 0.33, 0.67 <0.001
Age 529 0.99 0.97, 1.00 0.052
Gender



    Female 223 — —
    Male 305 1.15 0.80, 1.66 0.443
Race_Group



    White 327 — —
    Asian 26 0.90 0.38, 2.04 0.804
    Black 105 1.10 0.69, 1.75 0.703
    Other 69 1.00 0.58, 1.73 0.996
1 OR = Odds Ratio, CI = Confidence Interval

Multivariate logistic regression outcome Binary Outcome is 1 or more versus: 0 more_vs_zero_90days

Characteristic N OR1 95% CI1 p-value
group



    BWH 260 — —
    MGH 268 0.44 0.31, 0.63 <0.001
Age 529 0.99 0.97, 1.00 0.115
Gender



    Female 223 — —
    Male 305 1.26 0.86, 1.85 0.232
Race_Group



    White 327 — —
    Asian 26 0.83 0.35, 1.91 0.669
    Black 105 1.07 0.66, 1.75 0.781
    Other 69 0.99 0.56, 1.73 0.971
HTN



    N 12 — —
    Y 516 1.13 0.35, 3.93 0.835
DM



    N 120 — —
    Y 408 0.83 0.52, 1.33 0.439
CAD



    N 65 — —
    Y 463 0.79 0.44, 1.42 0.425
Dialysis_Vintage 529 0.90 0.85, 0.95 <0.001
HF_score 529 0.83 0.67, 1.04 0.101
1 OR = Odds Ratio, CI = Confidence Interval

Univariate logistic regression outcome Binary Outcome is 1 or more versus: 0 more_vs_zero_180days

Characteristic N OR1 95% CI1 p-value
group 529


    BWH
— —
    MGH
0.61 0.43, 0.86 0.005
Age 529 0.99 0.98, 1.00 0.191
Gender 529


    Female
— —
    Male
0.88 0.62, 1.24 0.463
Race_Group 529


    White
— —
    Asian
1.09 0.49, 2.45 0.831
    Black
1.16 0.74, 1.80 0.520
    Other
0.79 0.47, 1.33 0.378
HTN 529


    N
— —
    Y
0.53 0.14, 1.67 0.295
DM 529


    N
— —
    Y
1.16 0.77, 1.75 0.469
CAD 529


    N
— —
    Y
0.85 0.50, 1.43 0.543
Dialysis_Vintage 529 0.91 0.87, 0.96 <0.001
HF_score 529 0.96 0.78, 1.17 0.667
weight.ATE 529 1.00 0.87, 1.15 0.977
1 OR = Odds Ratio, CI = Confidence Interval

Multivariate logistic regression outcome Binary Outcome is 1 or more versus: 0 more_vs_zero_180days

Characteristic N OR1 95% CI1 p-value
group



    BWH 260 — —
    MGH 268 0.60 0.42, 0.85 0.004
Age 529 0.99 0.98, 1.00 0.167
Gender



    Female 223 — —
    Male 305 0.83 0.57, 1.18 0.300
Race_Group



    White 327 — —
    Asian 26 1.20 0.53, 2.72 0.665
    Black 105 1.03 0.65, 1.64 0.900
    Other 69 0.71 0.41, 1.22 0.221
1 OR = Odds Ratio, CI = Confidence Interval

Multivariate logistic regression outcome Binary Outcome is 1 or more versus: 0 more_vs_zero_180days

Characteristic N OR1 95% CI1 p-value
group



    BWH 260 — —
    MGH 268 0.57 0.40, 0.80 0.002
Age 529 0.99 0.98, 1.01 0.266
Gender



    Female 223 — —
    Male 305 0.87 0.60, 1.26 0.461
Race_Group



    White 327 — —
    Asian 26 1.17 0.51, 2.70 0.712
    Black 105 1.07 0.66, 1.74 0.786
    Other 69 0.70 0.40, 1.21 0.205
HTN



    N 12 — —
    Y 516 0.53 0.14, 1.71 0.305
DM



    N 120 — —
    Y 408 1.00 0.62, 1.58 0.983
CAD



    N 65 — —
    Y 463 0.86 0.48, 1.54 0.606
Dialysis_Vintage 529 0.91 0.86, 0.95 <0.001
HF_score 529 0.91 0.73, 1.13 0.398
1 OR = Odds Ratio, CI = Confidence Interval

Univariate linear regression decongestion_time_days

Characteristic N Beta 95% CI1 p-value
group 529


    BWH
— —
    MGH
-1.0 -1.6, -0.41 0.001
Age 529 -0.01 -0.04, 0.01 0.289
Gender 529


    Female
— —
    Male
0.04 -0.59, 0.66 0.906
Race_Group 529


    White
— —
    Asian
-1.1 -2.5, 0.30 0.124
    Black
-0.63 -1.4, 0.16 0.118
    Other
-0.68 -1.6, 0.25 0.154
HTN 529


    N
— —
    Y
-0.29 -2.3, 1.8 0.779
DM 529


    N
— —
    Y
0.80 0.07, 1.5 0.033
CAD 529


    N
— —
    Y
0.85 -0.08, 1.8 0.074
Dialysis_Vintage 529 -0.07 -0.13, -0.01 0.031
HF_score 529 0.34 -0.03, 0.71 0.071
weight.ATE 529 0.06 -0.19, 0.31 0.632
1 CI = Confidence Interval

linear regression decongestion_time_days Multivariate regression: age gender race

Characteristic Beta 95% CI1 p-value
group


    BWH — —
    MGH -1.0 -1.6, -0.44 <0.001
Age -0.02 -0.05, 0.01 0.117
Gender


    Female — —
    Male -0.07 -0.70, 0.56 0.829
Race_Group


    White — —
    Asian -0.93 -2.3, 0.48 0.197
    Black -0.86 -1.7, -0.05 0.039
    Other -0.76 -1.7, 0.18 0.113
1 CI = Confidence Interval

linear regression decongestion_time_days Multivariate regression:group+ Age+Gender+Race_Group+HTN+DM+CAD+Dialysis_Vintage+HF_score

Characteristic Beta 95% CI1 p-value
group


    BWH — —
    MGH -1.1 -1.7, -0.46 <0.001
Age -0.02 -0.05, 0.00 0.064
Gender


    Female — —
    Male -0.18 -0.81, 0.45 0.577
Race_Group


    White — —
    Asian -0.92 -2.3, 0.47 0.195
    Black -0.74 -1.6, 0.07 0.074
    Other -0.89 -1.8, 0.05 0.065
HTN


    N — —
    Y -0.06 -2.1, 1.9 0.949
DM


    N — —
    Y 0.50 -0.28, 1.3 0.210
CAD


    N — —
    Y 0.58 -0.40, 1.6 0.247
Dialysis_Vintage -0.06 -0.12, 0.01 0.080
HF_score 0.30 -0.07, 0.66 0.113
1 CI = Confidence Interval

Competing risk 1st_readmission_180

##      Estimate   Robust SE z-value    p-value    Hazard Ratio
## [1,] "$-0.427$" "$0.188$" "$-2.268$" "$0.023$*" "$0.652$"   
##      95\\% CI            
## [1,] "($0.451$, $0.944$)"

Univariate coxph time_1st_readmission_180

Characteristic N HR1 95% CI1 p-value
group 529 0.67 0.46, 0.96 0.029
Age 529 0.99 0.98, 1.01 0.278
Gender 529


    Female
— —
    Male
1.01 0.70, 1.46 0.952
Race_Group 529


    White
— —
    Asian
1.15 0.56, 2.37 0.698
    Black
1.22 0.77, 1.95 0.390
    Other
1.10 0.62, 1.94 0.747
HTN 529


    N
— —
    Y
0.72 0.31, 1.70 0.460
DM 529


    N
— —
    Y
1.16 0.74, 1.81 0.515
CAD 529


    N
— —
    Y
0.83 0.52, 1.34 0.454
Dialysis_Vintage 529 0.95 0.91, 0.99 0.021
HF_score 529 0.98 0.78, 1.22 0.828
HD_Unit 529


    No
— —
    Yes
0.90 0.52, 1.55 0.695
weight.ATE 529 1.03 0.85, 1.27 0.741
1 HR = Hazard Ratio, CI = Confidence Interval

coxph time_1st_readmission_180 Multivariate linear regression los: age gender race

Characteristic HR1 95% CI1 p-value
group 0.66 0.46, 0.95 0.026
Age 0.99 0.98, 1.01 0.315
Gender


    Female — —
    Male 1.02 0.69, 1.49 0.935
Race_Group


    White — —
    Asian 1.20 0.56, 2.59 0.634
    Black 1.17 0.73, 1.86 0.514
    Other 1.11 0.63, 1.95 0.725
1 HR = Hazard Ratio, CI = Confidence Interval

coxph time_1st_readmission_180 Multivariate linear regression:group+ Age+Gender+Race_Group+HTN+DM+CAD+Dialysis_Vintage+HF_score

Characteristic HR1 95% CI1 p-value
group 0.63 0.44, 0.92 0.017
Age 0.99 0.98, 1.01 0.417
Gender


    Female — —
    Male 1.08 0.72, 1.62 0.717
Race_Group


    White — —
    Asian 1.20 0.53, 2.68 0.665
    Black 1.19 0.75, 1.89 0.460
    Other 1.11 0.62, 1.97 0.729
HTN


    N — —
    Y 0.65 0.25, 1.65 0.362
DM


    N — —
    Y 1.06 0.65, 1.73 0.805
CAD


    N — —
    Y 0.81 0.47, 1.40 0.453
Dialysis_Vintage 0.95 0.91, 0.99 0.017
HF_score 0.94 0.73, 1.22 0.657
1 HR = Hazard Ratio, CI = Confidence Interval

decongestion_time_days,n_90,n_180,time_1st_readmission_180

1
(N=118)		 2
(N=159)		 Overall
(N=277)
decongestion_time_days
Mean (SD) 2.70 (3.21) 1.50 (1.80) 2.01 (2.56)
Median [Q1,Q3] 2.00 [0.250,3.75] 1.00 [0,2.00] 2.00 [0,3.00]
n_90
Mean (SD) 0.847 (0.975) 0.497 (0.778) 0.646 (0.883)
Median [Q1,Q3] 1.00 [0,1.00] 0 [0,1.00] 0 [0,1.00]
n_180
Mean (SD) 1.36 (1.63) 0.736 (1.03) 1.00 (1.35)
Median [Q1,Q3] 1.00 [0,2.00] 0 [0,1.00] 1.00 [0,1.00]
time_1st_readmission_180
Mean (SD) 99.7 (74.1) 123 (70.0) 113 (72.6)
Median [Q1,Q3] 88.5 [26.3,180] 180 [47.0,180] 169 [35.0,180]

HR Time to decongestion Multivariate model

Linear regression to decongestion Multivariate model