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Tabell för alla måndader

level Overall
n 30
Age (median [IQR]) 66.35 [52.57, 72.80]
BMI (median [IQR]) 24.71 [22.57, 28.12]
Gender (%) Female 14 (46.7)
Male 16 (53.3)
RemittingClinic (%) Blekinge 1 (3.3)
Halland 6 (20.0)
Kronoberg 4 (13.3)
Other 1 (3.3)
Skane 18 (60.0)
ASA (%) 1 5 (16.7)
2 10 (33.3)
3 15 (50.0)
Karnofsky (%) <70 4 (14.8)
70-80 6 (22.2)
90-100 17 (63.0)
Histology (%) Adenocarcinoma 21 (70.0)
Goblet 4 (13.3)
Mesothelioma 2 (6.7)
Pseudomyxom-adenocarc 3 (10.0)
MMR (%) pMMR 12 (100.0)
Mucinous (%) No 15 (68.2)
Yes 7 (31.8)
IndicationForHIPEC (%) Adenocarcinoma 21 (70.0)
Appendix Cancer 1 (3.3)
Goblet 3 (10.0)
Mesothelioma 2 (6.7)
Pseudomyxom-adenocarc 3 (10.0)
PresentationSymptoms (%) Intraoperative 1 (3.3)
Radiology 3 (10.0)
Symptoms 26 (86.7)
Differentiation (%) High 5 (38.5)
Low 4 (30.8)
Middel 4 (30.8)
SignetRingCells (%) No 20 (83.3)
Yes 4 (16.7)
Synchronous (%) No 8 (26.7)
Yes 22 (73.3)
PrimaryLocation (%) Appendix 9 (30.0)
Cekum 4 (13.3)
Left Colon 4 (13.3)
Peritoneum 2 (6.7)
Rigth colon 8 (26.7)
Small bowel 1 (3.3)
Transversum 2 (6.7)
PreviousSurgeryForCurrentMalignancy (%) No 3 (10.0)
Yes 27 (90.0)
PriorSurgicalScore (%) 0 2 (6.9)
1 7 (24.1)
2 16 (55.2)
3 4 (13.8)
PriorOstomy (%) No 19 (63.3)
Yes 11 (36.7)
PriorLaparotomyForCurrentMalignancy (%) No 11 (36.7)
Yes 19 (63.3)
PriorDiagnosticLarposcopy (%) No 13 (43.3)
Yes 17 (56.7)
DiagnosticLaparoscopytomiPCI (median [IQR]) 13.50 [10.00, 19.75]
CEA (median [IQR]) 6.00 [2.00, 28.00]
CA125 (median [IQR]) 60.00 [36.00, 123.00]
CA19 (median [IQR]) 32.50 [12.50, 137.75]
Albumin (median [IQR]) 37.00 [32.75, 38.00]
Trombocyter (median [IQR]) 361.50 [211.50, 439.00]
CRP (median [IQR]) 14.50 [7.95, 33.25]
WhyOpenClose (%) HighPCI 19 (63.3)
Other 6 (20.0)
SmallBowelInvolvment 5 (16.7)
IntraopPCI (median [IQR]) 30.00 [26.00, 34.00]
DurationOfSurgery.min (median [IQR]) 131.00 [115.25, 174.00]
IntraoperativeBleeding.ml (median [IQR]) 75.00 [50.00, 150.00]
ICU.d (%) 0 28 (93.3)
1 1 (3.3)
2 1 (3.3)
FreeSmallBowel (%) No 22 (81.5)
Yes 5 (18.5)
OtherConcomitantMetastases (%) No 27 (90.0)
Yes 3 (10.0)
RepeatCRS.HIPEC (%) No 27 (90.0)
Yes 3 (10.0)
Chemonaive (%) No 14 (48.3)
Yes 15 (51.7)
NeoadjuvantChemo (%) No 23 (79.3)
Yes 6 (20.7)
DischargeWhere (%) Home 15 (51.7)
HomeWithASIH 2 (6.9)
HomeWithAssistance 1 (3.4)
Hospital 11 (37.9)
Complications30d (%) No 21 (72.4)
Yes 8 (27.6)
Reop (%) No 29 (96.7)
Yes 1 (3.3)
AdjuvantChemo (%) No 6 (20.7)
Yes 23 (79.3)
AdjuvantChemoCycles (%) >6 12 (52.2)
0 3 (13.0)
2 1 (4.3)
3 2 (8.7)
4 2 (8.7)
5 1 (4.3)
6 2 (8.7)
Death (%) No 5 (16.7)
Yes 25 (83.3)
Stoma_formation (%) No 28 (93.3)
Yes 2 (6.7)
ClavienDindo (%) 0 22 (73.3)
2 4 (13.3)
3a 1 (3.3)
3b 1 (3.3)
4a 1 (3.3)
5 1 (3.3)
SeriousComplications (%) No 27 (90.0)
Yes 3 (10.0)
time_from_dian_lap_to_surgery (median [IQR]) 61.50 [44.00, 125.25]
PCIdifference (median [IQR]) 15.00 [8.75, 17.00]
length_of_stay (median [IQR]) 6.50 [5.00, 12.25]
level No Yes p test
n 6 23
Age (median [IQR]) 66.74 [58.40, 70.80] 60.44 [51.76, 71.34] 0.667 nonnorm
BMI (median [IQR]) 26.58 [23.55, 28.57] 24.39 [22.40, 27.28] 0.484 nonnorm
Gender (%) Female 3 (50.0) 11 (47.8) 1.000 exact
Male 3 (50.0) 12 (52.2)
RemittingClinic (%) Blekinge 0 (0.0) 0 (0.0) 0.634 exact
Halland 2 (33.3) 4 (17.4)
Kronoberg 0 (0.0) 4 (17.4)
Other 0 (0.0) 1 (4.3)
Skane 4 (66.7) 14 (60.9)
ASA (%) 1 1 (16.7) 4 (17.4) 1.000 exact
2 2 (33.3) 8 (34.8)
3 3 (50.0) 11 (47.8)
Karnofsky (%) <70 1 (16.7) 3 (15.0) 0.810 exact
70-80 2 (33.3) 4 (20.0)
90-100 3 (50.0) 13 (65.0)
Histology (%) Adenocarcinoma 6 (100.0) 14 (60.9) 0.649 exact
Goblet 0 (0.0) 4 (17.4)
Mesothelioma 0 (0.0) 2 (8.7)
Pseudomyxom-adenocarc 0 (0.0) 3 (13.0)
MMR (%) pMMR 3 (100.0) 9 (100.0) NA exact
Mucinous (%) No 5 (83.3) 10 (62.5) 0.616 exact
Yes 1 (16.7) 6 (37.5)
IndicationForHIPEC (%) Adenocarcinoma 6 (100.0) 14 (60.9) 0.712 exact
Appendix Cancer 0 (0.0) 1 (4.3)
Goblet 0 (0.0) 3 (13.0)
Mesothelioma 0 (0.0) 2 (8.7)
Pseudomyxom-adenocarc 0 (0.0) 3 (13.0)
PresentationSymptoms (%) Intraoperative 0 (0.0) 1 (4.3) 0.627 exact
Radiology 1 (16.7) 2 (8.7)
Symptoms 5 (83.3) 20 (87.0)
Differentiation (%) High 1 (33.3) 4 (40.0) 1.000 exact
Low 1 (33.3) 3 (30.0)
Middel 1 (33.3) 3 (30.0)
SignetRingCells (%) No 6 (100.0) 14 (77.8) 0.539 exact
Yes 0 (0.0) 4 (22.2)
Synchronous (%) No 2 (33.3) 6 (26.1) 1.000 exact
Yes 4 (66.7) 17 (73.9)
PrimaryLocation (%) Appendix 1 (16.7) 8 (34.8) 0.409 exact
Cekum 1 (16.7) 3 (13.0)
Left Colon 0 (0.0) 3 (13.0)
Peritoneum 0 (0.0) 2 (8.7)
Rigth colon 3 (50.0) 5 (21.7)
Small bowel 1 (16.7) 0 (0.0)
Transversum 0 (0.0) 2 (8.7)
PreviousSurgeryForCurrentMalignancy (%) No 0 (0.0) 3 (13.0) 1.000 exact
Yes 6 (100.0) 20 (87.0)
PriorSurgicalScore (%) 0 0 (0.0) 2 (8.7) 0.870 exact
1 1 (20.0) 6 (26.1)
2 4 (80.0) 11 (47.8)
3 0 (0.0) 4 (17.4)
PriorOstomy (%) No 4 (66.7) 15 (65.2) 1.000 exact
Yes 2 (33.3) 8 (34.8)
PriorLaparotomyForCurrentMalignancy (%) No 2 (33.3) 9 (39.1) 1.000 exact
Yes 4 (66.7) 14 (60.9)
PriorDiagnosticLarposcopy (%) No 1 (16.7) 11 (47.8) 0.354 exact
Yes 5 (83.3) 12 (52.2)
DiagnosticLaparoscopytomiPCI (median [IQR]) 13.00 [7.00, 16.00] 15.50 [10.75, 21.75] 0.247 nonnorm
CEA (median [IQR]) 2.50 [1.25, 6.00] 8.00 [2.50, 37.00] 0.249 nonnorm
CA125 (median [IQR]) 55.50 [53.50, 77.75] 75.00 [35.00, 206.50] 0.588 nonnorm
CA19 (median [IQR]) 29.50 [12.98, 32.75] 50.50 [13.00, 205.25] 0.317 nonnorm
Albumin (median [IQR]) 37.50 [36.25, 38.00] 37.00 [32.00, 38.00] 0.703 nonnorm
Trombocyter (median [IQR]) 316.00 [219.00, 404.00] 360.00 [218.50, 473.50] 0.667 nonnorm
CRP (median [IQR]) 14.00 [9.50, 28.00] 15.00 [7.60, 35.00] 0.845 nonnorm
WhyOpenClose (%) HighPCI 4 (66.7) 15 (65.2) 1.000 exact
Other 1 (16.7) 5 (21.7)
SmallBowelInvolvment 1 (16.7) 3 (13.0)
IntraopPCI (median [IQR]) 25.50 [24.25, 30.50] 30.00 [27.25, 34.00] 0.177 nonnorm
DurationOfSurgery.min (median [IQR]) 165.50 [142.75, 183.75] 120.00 [107.50, 162.50] 0.106 nonnorm
IntraoperativeBleeding.ml (median [IQR]) 200.00 [125.00, 250.00] 50.00 [50.00, 150.00] 0.249 nonnorm
ICU.d (%) 0 5 (83.3) 22 (95.7) 0.377 exact
1 1 (16.7) 0 (0.0)
2 0 (0.0) 1 (4.3)
FreeSmallBowel (%) No 4 (80.0) 17 (81.0) 1.000 exact
Yes 1 (20.0) 4 (19.0)
OtherConcomitantMetastases (%) No 4 (66.7) 22 (95.7) 0.100 exact
Yes 2 (33.3) 1 (4.3)
RepeatCRS.HIPEC (%) No 6 (100.0) 20 (87.0) 1.000 exact
Yes 0 (0.0) 3 (13.0)
Chemonaive (%) No 5 (83.3) 9 (40.9) 0.165 exact
Yes 1 (16.7) 13 (59.1)
NeoadjuvantChemo (%) No 3 (50.0) 19 (86.4) 0.091 exact
Yes 3 (50.0) 3 (13.6)
DischargeWhere (%) Home 3 (60.0) 12 (52.2) 0.428 exact
HomeWithASIH 1 (20.0) 1 (4.3)
HomeWithAssistance 0 (0.0) 1 (4.3)
Hospital 1 (20.0) 9 (39.1)
Complications30d (%) No 3 (50.0) 17 (77.3) 0.311 exact
Yes 3 (50.0) 5 (22.7)
Reop (%) No 6 (100.0) 22 (95.7) 1.000 exact
Yes 0 (0.0) 1 (4.3)
AdjuvantChemo (%) No 6 (100.0) 0 (0.0) <0.001 exact
Yes 0 (0.0) 23 (100.0)
AdjuvantChemoCycles (%) >6 0 (0.0) 12 (60.0) 0.004 exact
0 3 (100.0) 0 (0.0)
2 0 (0.0) 1 (5.0)
3 0 (0.0) 2 (10.0)
4 0 (0.0) 2 (10.0)
5 0 (0.0) 1 (5.0)
6 0 (0.0) 2 (10.0)
Death (%) No 0 (0.0) 5 (21.7) 0.553 exact
Yes 6 (100.0) 18 (78.3)
Stoma_formation (%) No 6 (100.0) 21 (91.3) 1.000 exact
Yes 0 (0.0) 2 (8.7)
ClavienDindo (%) 0 3 (50.0) 18 (78.3) 0.123 exact
2 1 (16.7) 3 (13.0)
3a 1 (16.7) 0 (0.0)
3b 0 (0.0) 1 (4.3)
4a 0 (0.0) 1 (4.3)
5 1 (16.7) 0 (0.0)
SeriousComplications (%) No 5 (83.3) 21 (91.3) 0.515 exact
Yes 1 (16.7) 2 (8.7)
time_from_dian_lap_to_surgery (median [IQR]) 106.00 [56.50, 127.75] 61.00 [42.00, 120.00] 0.567 nonnorm
PCIdifference (median [IQR]) 17.00 [13.00, 18.00] 15.00 [10.00, 16.25] 0.384 nonnorm
length_of_stay (median [IQR]) 8.00 [8.00, 19.00] 6.00 [5.00, 11.00] 0.108 nonnorm
Characteristic
Univariate CoxPh
Multivariate CoxPh
N HR 95% CI p-value HR 95% CI p-value
Age65 30 1.38 0.61, 3.13 0.44 1.33 0.40, 4.38 0.6
BMI25 30 1.77 0.73, 4.30 0.21 1.12 0.42, 3.02 0.8
CEA7 29 0.95 0.42, 2.16 0.90


CA125_60 25 0.95 0.38, 2.35 0.91


CA19_33 25 0.83 0.27, 2.56 0.74


CRP15 22 0.67 0.24, 1.89 0.45


Albumin37 28 0.54 0.21, 1.42 0.21


dianPCI13 22 1.00 0.39, 2.55 >0.99


intraPCI30 29 0.85 0.37, 1.93 0.69


PCIdiff20 22 0.91 0.20, 4.09 0.90


time_from_dian_lap_to_surgery62 26 1.29 0.52, 3.18 0.58


lengthofstay6 28 0.73 0.31, 1.74 0.47


Gender 30





    Female
— —
— —
    Male
0.71 0.30, 1.71 0.44 1.43 0.48, 4.30 0.5
RemittingClinic 30





    Blekinge
— —



    Halland
3.95 0.46, 34.1 0.21


    Kronoberg
3.28 0.34, 31.7 0.31


    Other
5.48 0.30, 98.6 0.25


    Skane
2.53 0.30, 21.1 0.39


ASA 30





    1
— —



    2
0.65 0.18, 2.34 0.51


    3
1.18 0.38, 3.65 0.77


Karnofsky 27





    <70
— —



    70-80
0.30 0.07, 1.33 0.11


    90-100
0.36 0.11, 1.20 0.10


IndicationForHIPEC 30





    Adenocarcinoma
— —



    Appendix Cancer
2.49 0.31, 19.9 0.39


    Goblet
1.05 0.30, 3.67 0.94


    Mesothelioma
0.69 0.15, 3.17 0.63


    Pseudomyxom-adenocarc
0.35 0.08, 1.56 0.17


SignetRingCells 24





    No
— —



    Yes
0.78 0.22, 2.74 0.69


Synchronous 30





    No
— —



    Yes
1.46 0.54, 3.95 0.45


PrimaryLocation 30





    Appendix
— —



    Cekum
1.58 0.45, 5.57 0.47


    Left Colon
0.54 0.11, 2.64 0.44


    Peritoneum
0.99 0.20, 5.05 >0.99


    Rigth colon
2.21 0.70, 6.98 0.18


    Small bowel
2.48 0.29, 21.5 0.41


    Transversum
2.63 0.52, 13.3 0.24


PreviousSurgeryForCurrentMalignancy 30





    No
— —



    Yes
1.42 0.41, 4.89 0.58


PriorSurgicalScore 29





    0
— —



    1
1.86 0.37, 9.36 0.45


    2
1.10 0.24, 5.11 0.90


    3
0.38 0.05, 2.82 0.34


PriorOstomy 30





    No
— —



    Yes
1.00 0.43, 2.30 >0.99


PriorLaparotomyForCurrentMalignancy 30





    No
— —



    Yes
0.59 0.25, 1.39 0.23


PriorDiagnosticLarposcopy 30





    No
— —



    Yes
1.90 0.81, 4.41 0.14


WhyOpenClose 30





    HighPCI
— —



    Other
0.47 0.16, 1.35 0.16


    SmallBowelInvolvment
0.62 0.19, 1.96 0.41


ICU.d 30





    0
— —



    1






    2
2.46 0.31, 19.5 0.39


FreeSmallBowel 27





    No
— —



    Yes
1.22 0.44, 3.39 0.71


OtherConcomitantMetastases 30





    No
— —



    Yes
3.05 0.87, 10.7 0.081


RepeatCRS.HIPEC 30





    No
— —



    Yes
0.16 0.02, 1.22 0.077


Chemonaive 29





    No
— —



    Yes
0.97 0.42, 2.22 0.94


NeoadjuvantChemo 29





    No
— —



    Yes
2.32 0.88, 6.13 0.089


DischargeWhere 29





    Home
— —



    HomeWithASIH
0.97 0.19, 4.81 0.97


    HomeWithAssistance
1.18 0.15, 9.32 0.88


    Hospital
1.06 0.41, 2.75 0.90


Complications30d 29





    No
— —



    Yes
1.61 0.65, 4.00 0.30


Reop 30





    No
— —



    Yes
1.11 0.15, 8.43 0.92


AdjuvantChemo 29





    No
— —
— —
    Yes
0.12 0.04, 0.37 <0.001 0.12 0.03, 0.44 0.001
Stoma_formation 30





    No
— —



    Yes
2.09 0.47, 9.39 0.33


Abbreviations: CI = Confidence Interval, HR = Hazard Ratio 

## Call: survfit(formula = Surv((opcl$Fy * 12), opcl$Death) ~ 1, data = opcl)
## 
##       n events median 0.95LCL 0.95UCL
## [1,] 30     24   10.4    6.44    17.9
## Call: survfit(formula = Surv((opcl$Fy * 12), opcl$Death) ~ opcl$AdjuvantChemo, 
##     data = opcl)
## 
##    1 observation deleted due to missingness 
##                         n events median 0.95LCL 0.95UCL
## opcl$AdjuvantChemo=No   6      6    3.5    2.69      NA
## opcl$AdjuvantChemo=Yes 23     17   13.4    9.53    18.1