## Warning: package 'survival' is in use and will not be installed
## Warning: package 'survival' is in use and will not be installed
## Warning: package 'survminer' is in use and will not be installed
## Warning: package 'ggplot2' is in use and will not be installed

## Call:
## survdiff(formula = Surv(time, status) ~ sex, data = lung)
## 
##         N Observed Expected (O-E)^2/E (O-E)^2/V
## sex=1 138      112     91.6      4.55      10.3
## sex=2  90       53     73.4      5.68      10.3
## 
##  Chisq= 10.3  on 1 degrees of freedom, p= 0.001
## Call:
## coxph(formula = Surv(time, status) ~ age + sex + ph.ecog, data = lung)
## 
##   n= 227, number of events= 164 
##    (1 observation deleted due to missingness)
## 
##              coef exp(coef)  se(coef)      z Pr(>|z|)    
## age      0.011067  1.011128  0.009267  1.194 0.232416    
## sex     -0.552612  0.575445  0.167739 -3.294 0.000986 ***
## ph.ecog  0.463728  1.589991  0.113577  4.083 4.45e-05 ***
## ---
## Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
## 
##         exp(coef) exp(-coef) lower .95 upper .95
## age        1.0111     0.9890    0.9929    1.0297
## sex        0.5754     1.7378    0.4142    0.7994
## ph.ecog    1.5900     0.6289    1.2727    1.9864
## 
## Concordance= 0.637  (se = 0.025 )
## Likelihood ratio test= 30.5  on 3 df,   p=1e-06
## Wald test            = 29.93  on 3 df,   p=1e-06
## Score (logrank) test = 30.5  on 3 df,   p=1e-06
##         chisq df    p
## age     0.188  1 0.66
## sex     2.305  1 0.13
## ph.ecog 2.054  1 0.15
## GLOBAL  4.464  3 0.22