Gothenburg
(N=424)
Northern
(N=493)
Stockholm CFN Karolinska
(N=1441)
Stockholm Danderyd
(N=328)
Overall
(N=2686)
Sex
Kvinna 282 (66.5%) 330 (66.9%) 993 (68.9%) 232 (70.7%) 1837 (68.4%)
Man 142 (33.5%) 162 (32.9%) 447 (31.0%) 96 (29.3%) 847 (31.5%)
Missing 0 (0%) 1 (0.2%) 1 (0.1%) 0 (0%) 2 (0.1%)
Age
Mean (SD) 43.5 (12.3) 40.7 (11.6) 41.9 (11.6) 41.7 (10.8) 41.9 (11.6)
Median [Min, Max] 43.0 [9.70, 74.6] 40.8 [13.5, 75.1] 41.8 [14.4, 77.1] 41.7 [15.7, 69.6] 41.9 [9.70, 77.1]
Missing 0 (0%) 1 (0.2%) 2 (0.1%) 0 (0%) 3 (0.1%)
BMI
Mean (SD) 25.6 (4.94) 27.4 (6.94) 25.3 (5.11) 25.8 (5.47) 25.7 (5.46)
Median [Min, Max] 24.7 [17.5, 46.6] 25.2 [16.3, 49.8] 24.3 [14.5, 61.6] 25.2 [13.7, 49.9] 24.6 [13.7, 61.6]
Missing 252 (59.4%) 288 (58.4%) 477 (33.1%) 111 (33.8%) 1128 (42.0%)
MS type
NA 1 (0.2%) 0 (0%) 2 (0.1%) 1 (0.3%) 4 (0.1%)
PPMS 38 (9.0%) 28 (5.7%) 72 (5.0%) 6 (1.8%) 144 (5.4%)
RRMS 278 (65.6%) 381 (77.3%) 1006 (69.8%) 266 (81.1%) 1931 (71.9%)
SPMS 107 (25.2%) 84 (17.0%) 361 (25.1%) 55 (16.8%) 607 (22.6%)
EDSS
Mean (SD) 3.09 (2.14) 2.17 (1.89) 2.82 (1.94) 2.10 (1.74) 2.68 (1.98)
Median [Min, Max] 2.50 [0, 8.75] 2.00 [0, 8.00] 2.50 [0, 8.75] 1.75 [0, 9.00] 2.00 [0, 9.00]
Missing 55 (13.0%) 186 (37.7%) 279 (19.4%) 38 (11.6%) 558 (20.8%)
Previous treatment
Cladribine 23 (5.4%) 1 (0.2%) 16 (1.1%) 2 (0.6%) 42 (1.6%)
Fumarate 36 (8.5%) 20 (4.1%) 125 (8.7%) 44 (13.4%) 225 (8.4%)
Glatiramer_acetate 12 (2.8%) 20 (4.1%) 61 (4.2%) 13 (4.0%) 106 (3.9%)
Interferon 41 (9.7%) 118 (23.9%) 297 (20.6%) 60 (18.3%) 516 (19.2%)
Natalizumab 118 (27.8%) 104 (21.1%) 242 (16.8%) 76 (23.2%) 540 (20.1%)
Other 24 (5.7%) 32 (6.5%) 54 (3.7%) 10 (3.0%) 120 (4.5%)
Other Anti-CD20 8 (1.9%) 1 (0.2%) 30 (2.1%) 10 (3.0%) 49 (1.8%)
S1PR-inhibitors 30 (7.1%) 21 (4.3%) 147 (10.2%) 15 (4.6%) 213 (7.9%)
Teriflunomide 15 (3.5%) 1 (0.2%) 22 (1.5%) 5 (1.5%) 43 (1.6%)
Missing 117 (27.6%) 175 (35.5%) 447 (31.0%) 93 (28.4%) 832 (31.0%)
IgG
Mean (SD) 9.59 (2.23) 9.56 (2.17) 10.0 (2.18) 9.78 (2.06) 9.84 (2.18)
Median [Min, Max] 9.40 [2.30, 17.0] 9.41 [4.26, 19.0] 9.84 [4.37, 20.6] 9.69 [4.98, 16.3] 9.67 [2.30, 20.6]
Missing 5 (1.2%) 5 (1.0%) 9 (0.6%) 0 (0%) 19 (0.7%)
Neutrophils
Mean (SD) 4.17 (1.27) 4.01 (1.15) 4.09 (1.36) 3.84 (1.17) 4.06 (1.29)
Median [Min, Max] 3.95 [1.12, 11.4] 3.90 [1.83, 9.38] 3.87 [1.22, 15.2] 3.72 [1.03, 10.0] 3.87 [1.03, 15.2]