Gothenburg
(N=424)
Northern
(N=493)
Stockholm CFN Karolinska
(N=1445)
Stockholm Danderyd
(N=328)
Overall
(N=2690)
Sex
Female 282 (66.5%) 330 (66.9%) 995 (68.9%) 232 (70.7%) 1839 (68.4%)
Male 142 (33.5%) 162 (32.9%) 449 (31.1%) 96 (29.3%) 849 (31.6%)
Missing 0 (0%) 1 (0.2%) 1 (0.1%) 0 (0%) 2 (0.1%)
Age
Mean (SD) 43.5 (12.3) 40.7 (11.6) 42.0 (11.6) 41.7 (10.8) 41.9 (11.6)
Median [Min, Max] 43.0 [9.70, 74.6] 40.8 [13.5, 75.1] 41.8 [14.4, 77.7] 41.7 [15.7, 69.6] 41.9 [9.70, 77.7]
Missing 0 (0%) 1 (0.2%) 2 (0.1%) 0 (0%) 3 (0.1%)
BMI
Mean (SD) 25.6 (4.94) 27.4 (6.94) 25.3 (5.11) 25.8 (5.47) 25.7 (5.46)
Median [Min, Max] 24.7 [17.5, 46.6] 25.2 [16.3, 49.8] 24.3 [14.5, 61.6] 25.2 [13.7, 49.9] 24.6 [13.7, 61.6]
Missing 252 (59.4%) 288 (58.4%) 478 (33.1%) 111 (33.8%) 1129 (42.0%)
MS type
NA 1 (0.2%) 0 (0%) 2 (0.1%) 1 (0.3%) 4 (0.1%)
PPMS 38 (9.0%) 28 (5.7%) 72 (5.0%) 6 (1.8%) 144 (5.4%)
RRMS 278 (65.6%) 381 (77.3%) 1007 (69.7%) 266 (81.1%) 1932 (71.8%)
SPMS 107 (25.2%) 84 (17.0%) 364 (25.2%) 55 (16.8%) 610 (22.7%)
EDSS
Mean (SD) 3.09 (2.14) 2.17 (1.89) 2.83 (1.94) 2.10 (1.74) 2.68 (1.98)
Median [Min, Max] 2.50 [0, 8.75] 2.00 [0, 8.00] 2.50 [0, 8.75] 1.75 [0, 9.00] 2.00 [0, 9.00]
Missing 55 (13.0%) 186 (37.7%) 280 (19.4%) 38 (11.6%) 559 (20.8%)
Previous treatment
Cladribine 2 (0.5%) 4 (0.8%) 12 (0.8%) 2 (0.6%) 20 (0.7%)
Dimethyl_fumarate 13 (3.1%) 10 (2.0%) 45 (3.1%) 11 (3.4%) 79 (2.9%)
Fingolimod 16 (3.8%) 13 (2.6%) 42 (2.9%) 5 (1.5%) 76 (2.8%)
Glatiramer_acetate 17 (4.0%) 9 (1.8%) 50 (3.5%) 6 (1.8%) 82 (3.0%)
Interferon 73 (17.2%) 78 (15.8%) 203 (14.0%) 62 (18.9%) 416 (15.5%)
Natalizumab 149 (35.1%) 146 (29.6%) 510 (35.3%) 95 (29.0%) 900 (33.5%)
Other 11 (2.6%) 7 (1.4%) 44 (3.0%) 13 (4.0%) 75 (2.8%)
Other Anti-CD20 7 (1.7%) 12 (2.4%) 28 (1.9%) 4 (1.2%) 51 (1.9%)
Teriflunomide 3 (0.7%) 5 (1.0%) 4 (0.3%) 1 (0.3%) 13 (0.5%)
treatment_naive 133 (31.4%) 209 (42.4%) 507 (35.1%) 129 (39.3%) 978 (36.4%)
IgG
Mean (SD) 9.59 (2.23) 9.56 (2.17) 10.0 (2.18) 9.78 (2.06) 9.84 (2.18)
Median [Min, Max] 9.40 [2.30, 17.0] 9.41 [4.26, 19.0] 9.85 [3.20, 20.6] 9.69 [4.98, 16.3] 9.68 [2.30, 20.6]
Missing 5 (1.2%) 5 (1.0%) 10 (0.7%) 0 (0%) 20 (0.7%)
Neutrophils
Mean (SD) 4.17 (1.27) 4.02 (1.16) 4.10 (1.37) 3.85 (1.17) 4.07 (1.30)
Median [Min, Max] 3.95 [1.12, 11.4] 3.90 [1.83, 9.38] 3.88 [1.22, 15.2] 3.74 [1.03, 10.0] 3.87 [1.03, 15.2]