Table 1

0
(N=118)		 1
(N=160)		 Overall
(N=278)
Gender
Female 54 (45.8%) 63 (39.4%) 117 (42.1%)
Male 64 (54.2%) 97 (60.6%) 161 (57.9%)
Age
Mean (SD) 68.1 (13.2) 70.7 (11.4) 69.6 (12.2)
Median [Q1,Q3] 69.0 [58.3,78.0] 71.0 [64.8,79.0] 70.0 [62.0,78.0]
Race_Group
White 66 (55.9%) 107 (66.9%) 173 (62.2%)
Asian 5 (4.2%) 11 (6.9%) 16 (5.8%)
Black 28 (23.7%) 25 (15.6%) 53 (19.1%)
Other 19 (16.1%) 17 (10.6%) 36 (12.9%)
LOS
Mean (SD) 11.2 (10.6) 8.48 (6.30) 9.62 (8.49)
Median [Q1,Q3] 7.00 [4.25,13.5] 7.00 [4.00,10.3] 7.00 [4.00,11.0]
HTN
N 2 (1.7%) 5 (3.1%) 7 (2.5%)
Y 116 (98.3%) 155 (96.9%) 271 (97.5%)
DM
N 24 (20.3%) 41 (25.6%) 65 (23.4%)
Y 94 (79.7%) 119 (74.4%) 213 (76.6%)
CAD
N 15 (12.7%) 20 (12.5%) 35 (12.6%)
Y 103 (87.3%) 140 (87.5%) 243 (87.4%)
Hgb
Mean (SD) 9.94 (1.50) 10.1 (1.72) 10.0 (1.63)
Median [Q1,Q3] 9.80 [8.93,10.8] 10.0 [8.90,11.2] 9.95 [8.90,11.1]
HCT_admit
Mean (SD) 31.4 (4.84) 31.9 (5.58) 31.7 (5.28)
Median [Q1,Q3] 31.2 [28.1,34.4] 31.5 [28.1,35.3] 31.3 [28.1,35.2]
HCT_discharge
Mean (SD) 29.2 (3.94) 30.7 (4.56) 30.1 (4.36)
Median [Q1,Q3] 29.0 [26.6,31.7] 30.4 [27.5,33.2] 29.8 [27.0,32.4]
Iron
Mean (SD) 54.4 (27.4) 51.4 (32.5) 52.5 (30.7)
Median [Q1,Q3] 49.0 [37.5,67.0] 44.0 [31.0,60.0] 45.0 [32.4,63.3]
Missing 35 (29.7%) 19 (11.9%) 54 (19.4%)
Ferritin
Mean (SD) 985 (769) 1310 (3960) 1190 (3190)
Median [Q1,Q3] 785 [326,1430] 818 [438,1310] 806 [368,1370]
Missing 39 (33.1%) 22 (13.8%) 61 (21.9%)
TIBC
Mean (SD) 195 (50.8) 196 (62.9) 195 (58.6)
Median [Q1,Q3] 188 [162,224] 190 [160,224] 190 [161,224]
Missing 38 (32.2%) 24 (15.0%) 62 (22.3%)
TSAT
Mean (SD) 21.9 (8.52) 36.5 (48.5) 35.0 (46.2)
Median [Q1,Q3] 18.5 [16.5,28.0] 25.0 [17.5,34.0] 23.0 [17.0,34.0]
Missing 110 (93.2%) 89 (55.6%) 199 (71.6%)
NT_proBNP
Mean (SD) 43100 (34800) 46400 (48300) 45100 (43300)
Median [Q1,Q3] 35200 [15900,70000] 31500 [14400,58300] 32300 [14700,64900]
Missing 14 (11.9%) 8 (5.0%) 22 (7.9%)
troponin_T
Mean (SD) 0.388 (0.649) 1.02 (7.11) 0.765 (5.49)
Median [Q1,Q3] 0.160 [0.0600,0.330] 0.110 [0.0600,0.230] 0.120 [0.0600,0.258]
Missing 57 (48.3%) 71 (44.4%) 128 (46.0%)
hTS
Mean (SD) 267 (381) 213 (324) 236 (348)
Median [Q1,Q3] 168 [75.5,275] 128 [81.8,253] 145 [78.5,270]
Missing 72 (61.0%) 96 (60.0%) 168 (60.4%)
RVSP
Mean (SD) 45.6 (16.4) 49.7 (13.3) 47.8 (14.9)
Median [Q1,Q3] 44.0 [34.8,54.9] 48.0 [41.0,56.5] 46.0 [38.8,55.0]
Missing 33 (28.0%) 61 (38.1%) 94 (33.8%)
EF
Mean (SD) 48.4 (14.5) 55.2 (16.4) 52.3 (15.9)
Median [Q1,Q3] 50.0 [40.0,60.0] 59.0 [46.5,67.0] 55.0 [40.0,65.0]
Missing 21 (17.8%) 28 (17.5%) 49 (17.6%)
LA_index
Mean (SD) 52.1 (20.3) 46.9 (11.6) 47.7 (13.2)
Median [Q1,Q3] 44.7 [38.8,54.6] 46.2 [40.1,53.2] 46.1 [40.0,53.4]
Missing 99 (83.9%) 43 (26.9%) 142 (51.1%)
UF_rate
Mean (SD) 10.3 (6.01) 9.88 (4.15) 10.1 (5.02)
Median [Q1,Q3] 9.52 [6.17,12.8] 9.46 [6.84,12.7] 9.46 [6.78,12.8]
EDW
Mean (SD) 76.9 (22.6) 78.1 (21.6) 77.6 (22.0)
Median [Q1,Q3] 74.9 [60.0,87.3] 72.5 [64.8,92.8] 74.5 [63.0,90.0]
Missing 0 (0%) 1 (0.6%) 1 (0.4%)
admit_Weight
Mean (SD) 80.7 (22.9) 82.4 (22.5) 81.7 (22.6)
Median [Q1,Q3] 77.7 [64.0,90.2] 77.2 [67.9,97.2] 77.6 [65.9,93.7]
Missing 1 (0.8%) 0 (0%) 1 (0.4%)
HF_score
1 33 (28.0%) 60 (37.5%) 93 (33.5%)
2 33 (28.0%) 54 (33.8%) 87 (31.3%)
3 52 (44.1%) 46 (28.8%) 98 (35.3%)
Dialysis_Vintage
Mean (SD) 3.35 (4.55) 3.39 (3.40) 3.37 (3.92)
Median [Q1,Q3] 2.00 [1.00,4.00] 2.00 [1.00,4.00] 2.00 [1.00,4.00]
Access_type
AVF 88 (74.6%) 93 (58.1%) 181 (65.1%)
AVG 7 (5.9%) 23 (14.4%) 30 (10.8%)
TDC 23 (19.5%) 44 (27.5%) 67 (24.1%)
decongestion_time_days
Mean (SD) 2.70 (3.21) 1.49 (1.79) 2.00 (2.56)
Median [Q1,Q3] 2.00 [0.250,3.75] 1.00 [0,2.00] 2.00 [0,3.00]
type_of_oxygen
Bipap to RA 0 (0%) 1 (0.6%) 1 (0.4%)
CPAP to RA 0 (0%) 1 (0.6%) 1 (0.4%)
Intubated to RA 0 (0%) 2 (1.3%) 2 (0.7%)
Intube to RA 2 (1.7%) 0 (0%) 2 (0.7%)
NC to Baseline 2 (1.7%) 0 (0%) 2 (0.7%)
NC to baseline NC 2 (1.7%) 15 (9.4%) 17 (6.1%)
NC to NC 0 (0%) 1 (0.6%) 1 (0.4%)
NC to RA 77 (65.3%) 79 (49.4%) 156 (56.1%)
NINV to baseline NC 1 (0.8%) 0 (0%) 1 (0.4%)
NINV to RA 3 (2.5%) 0 (0%) 3 (1.1%)
NRB to NC 0 (0%) 1 (0.6%) 1 (0.4%)
NRB to RA 0 (0%) 3 (1.9%) 3 (1.1%)
RA 31 (26.3%) 56 (35.0%) 87 (31.3%)
Vent to RA 0 (0%) 1 (0.6%) 1 (0.4%)
n_90
Mean (SD) 0.847 (0.975) 0.506 (0.785) 0.651 (0.885)
Median [Q1,Q3] 1.00 [0,1.00] 0 [0,1.00] 0 [0,1.00]
n_180
Mean (SD) 1.36 (1.63) 0.763 (1.08) 1.01 (1.37)
Median [Q1,Q3] 1.00 [0,2.00] 0 [0,1.00] 1.00 [0,1.00]

Balance check before

## Balance Measures
##                     Type  M.0.Un SD.0.Un  M.1.Un SD.1.Un Diff.Un
## Age              Contin. 68.0508 13.2277 70.7312 11.3590  0.2174
## Race_Group_White  Binary  0.5593       .  0.6688       .  0.1094
## Race_Group_Asian  Binary  0.0424       .  0.0688       .  0.0264
## Race_Group_Black  Binary  0.2373       .  0.1562       . -0.0810
## Race_Group_Other  Binary  0.1610       .  0.1062       . -0.0548
## Gender_Male       Binary  0.5424       .  0.6062       .  0.0639
## CAD_Y             Binary  0.8729       .  0.8750       .  0.0021
## HTN_Y             Binary  0.9831       .  0.9688       . -0.0143
## DM_Y              Binary  0.7966       .  0.7438       . -0.0529
## HF_score_1        Binary  0.2797       .  0.3750       .  0.0953
## HF_score_2        Binary  0.2797       .  0.3375       .  0.0578
## HF_score_3        Binary  0.4407       .  0.2875       . -0.1532
## Dialysis_Vintage Contin.  3.3475  4.5524  3.3937  3.3983  0.0115
## 
## Sample sizes
##     Control Treated
## All     118     160

Balance check after

## Balance Measures
##                     Type M.0.Adj SD.0.Adj M.1.Adj SD.1.Adj Diff.Adj
## Age              Contin. 69.5203  11.9377 69.0118  12.9739  -0.0412
## Race_Group_White  Binary  0.6429        .  0.6106        .  -0.0323
## Race_Group_Asian  Binary  0.0407        .  0.0569        .   0.0162
## Race_Group_Black  Binary  0.1879        .  0.1984        .   0.0104
## Race_Group_Other  Binary  0.1285        .  0.1341        .   0.0056
## Gender_Male       Binary  0.5951        .  0.5749        .  -0.0201
## CAD_Y             Binary  0.8897        .  0.8682        .  -0.0215
## HTN_Y             Binary  0.9851        .  0.9728        .  -0.0123
## DM_Y              Binary  0.7706        .  0.7794        .   0.0089
## HF_score_1        Binary  0.3044        .  0.3446        .   0.0402
## HF_score_2        Binary  0.3119        .  0.2914        .  -0.0205
## HF_score_3        Binary  0.3837        .  0.3641        .  -0.0196
## Dialysis_Vintage Contin.  4.0389   6.5613  3.3245   3.3107  -0.1778
## 
## Effective sample sizes
##            Control Treated
## Unadjusted   118.   160.  
## Adjusted     102.2  138.43

Univariate linear regression outcome los

outcome los
Characteristic N Beta 95% CI1 p-value
group 551


    BWH
— —
    MGH
-2.6 -4.6, -0.57 0.012
Age 551 0.01 -0.07, 0.09 0.840
Gender 551


    Female
— —
    Male
1.3 -0.72, 3.4 0.205
Race_Group 551


    White
— —
    Asian
-4.7 -9.4, -0.04 0.049
    Black
-3.4 -6.0, -0.78 0.011
    Other
-3.1 -6.2, -0.11 0.043
HTN 551


    N
— —
    Y
-4.4 -11, 2.6 0.217
DM 551


    N
— —
    Y
1.7 -0.73, 4.1 0.173
CAD 551


    N
— —
    Y
4.5 1.4, 7.6 0.004
Dialysis_Vintage 551 0.18 -0.01, 0.38 0.066
HF_score 551


    1
— —
    2
0.22 -2.3, 2.8 0.864
    3
3.0 0.55, 5.4 0.017
weight.ATE 551 0.11 -0.81, 1.0 0.809
1 CI = Confidence Interval

Univariate linear regression outcome log_los

outcome log_los
Characteristic N Beta 95% CI1 p-value
group 551


    BWH
— —
    MGH
-12.59 -26.64, 4.15 0.133
Age 551 0.24 -0.47, 0.95 0.509
Gender 551


    Female
— —
    Male
11.43 -6.75, 33.16 0.235
Race_Group 551


    White
— —
    Asian
-33.01 -55.42, 0.68 0.055
    Black
-24.43 -39.69, -5.29 0.016
    Other
-22.24 -40.23, 1.18 0.062
HTN 551


    N
— —
    Y
-28.76 -61.34, 31.28 0.278
DM 551


    N
— —
    Y
29.89 5.45, 59.99 0.015
CAD 551


    N
— —
    Y
54.33 18.43, 101.12 0.001
Dialysis_Vintage 551 1.59 -0.11, 3.32 0.068
HF_score 551


    1
— —
    2
1.84 -18.28, 26.90 0.871
    3
29.11 4.78, 59.08 0.017
weight.ATE 551 0.21 -7.51, 8.58 0.959
1 CI = Confidence Interval

Multivariate linear regression los: age gender race

outcome los
Characteristic N Beta 95% CI1 p-value
group



    BWH 274 — —
    MGH 276 -2.5 -4.4, -0.46 0.016
Age 551 -0.02 -0.10, 0.07 0.654
Gender



    Female 228 — —
    Male 322 0.95 -1.1, 3.0 0.370
Race_Group



    White 345 — —
    Asian 26 -4.4 -9.0, 0.32 0.069
    Black 106 -3.5 -6.2, -0.78 0.012
    Other 72 -2.8 -5.9, 0.28 0.076
1 CI = Confidence Interval

Multivariate linear regression log_los : age gender race

outcome log_los
Characteristic N Beta 95% CI1 p-value
group



    BWH 274 — —
    MGH 276 -11.52 -25.63, 5.27 0.169
Age 551 0.04 -0.70, 0.78 0.918
Gender



    Female 228 — —
    Male 322 8.49 -9.47, 30.01 0.378
Race_Group



    White 345 — —
    Asian 26 -32.11 -54.92, 2.25 0.065
    Black 106 -23.86 -39.98, -3.40 0.026
    Other 72 -19.78 -38.83, 5.19 0.112
1 CI = Confidence Interval

Multivariate linear regression los ： group+ Age+Gender+Race_Group+HTN+DM+CAD+Dialysis_Vintage+HF_score

outcome los
Characteristic N Beta 95% CI1 p-value
group



    BWH 274 — —
    MGH 276 -2.3 -4.2, -0.31 0.024
Age 551 -0.04 -0.13, 0.04 0.353
Gender



    Female 228 — —
    Male 322 0.21 -1.9, 2.3 0.842
Race_Group



    White 345 — —
    Asian 26 -3.9 -8.5, 0.66 0.095
    Black 106 -3.0 -5.7, -0.28 0.032
    Other 72 -2.7 -5.8, 0.39 0.088
HTN



    N 11 — —
    Y 539 -3.5 -10, 3.3 0.314
DM



    N 124 — —
    Y 427 1.7 -0.79, 4.3 0.178
CAD



    N 66 — —
    Y 484 3.3 0.01, 6.5 0.050
Dialysis_Vintage 551 0.24 0.04, 0.43 0.020
HF_score



    1 178 — —
    2 166 -0.04 -2.6, 2.5 0.977
    3 206 2.8 0.42, 5.3 0.022
1 CI = Confidence Interval

Multivariate linear regression log_los ： group+ Age+Gender+Race_Group+HTN+DM+CAD+Dialysis_Vintage+HF_score

outcome log_los
Characteristic N Beta 95% CI1 p-value
group



    BWH 274 — —
    MGH 276 -0.10 -0.27, 0.06 0.228
Age 551 0.00 -0.01, 0.01 0.726
Gender



    Female 228 — —
    Male 322 0.01 -0.17, 0.19 0.916
Race_Group



    White 345 — —
    Asian 26 -0.34 -0.74, 0.05 0.091
    Black 106 -0.23 -0.46, 0.01 0.059
    Other 72 -0.23 -0.50, 0.04 0.090
HTN



    N 11 — —
    Y 539 -0.26 -0.85, 0.33 0.383
DM



    N 124 — —
    Y 427 0.28 0.06, 0.50 0.014
CAD



    N 66 — —
    Y 484 0.28 0.00, 0.57 0.048
Dialysis_Vintage 551 0.02 0.01, 0.04 0.007
HF_score



    1 178 — —
    2 166 0.00 -0.22, 0.22 0.989
    3 206 0.24 0.03, 0.45 0.024
1 CI = Confidence Interval

90 days poisson regression: group

Characteristic N IRR1 95% CI1 p-value
group



    BWH 274 — —
    MGH 276 0.69 0.56, 0.85 <0.001
1 IRR = Incidence Rate Ratio, CI = Confidence Interval

90 days poisson regression: group Age Gender Race_Group

Characteristic N IRR1 95% CI1 p-value
group



    BWH 274 — —
    MGH 276 0.67 0.54, 0.83 <0.001
Age 551 0.99 0.98, 1.00 0.019
Gender



    Female 228 — —
    Male 322 1.25 1.00, 1.56 0.049
Race_Group



    White 345 — —
    Asian 26 1.01 0.56, 1.68 0.971
    Black 106 1.56 1.21, 2.01 <0.001
    Other 72 1.29 0.93, 1.76 0.119
1 IRR = Incidence Rate Ratio, CI = Confidence Interval

90 days poisson regression： group+ Age+Gender+Race_Group+HTN+DM+CAD+Dialysis_Vintage+HF_score

Characteristic N IRR1 95% CI1 p-value
group



    BWH 274 — —
    MGH 276 0.66 0.53, 0.81 <0.001
Age 551 0.99 0.98, 1.00 0.043
Gender



    Female 228 — —
    Male 322 1.30 1.04, 1.64 0.023
Race_Group



    White 345 — —
    Asian 26 0.95 0.53, 1.58 0.865
    Black 106 1.51 1.16, 1.96 0.002
    Other 72 1.26 0.90, 1.74 0.159
HTN



    N 11 — —
    Y 539 0.89 0.46, 2.07 0.768
DM



    N 124 — —
    Y 427 1.01 0.76, 1.34 0.968
CAD



    N 66 — —
    Y 484 0.92 0.66, 1.31 0.644
Dialysis_Vintage 551 0.94 0.91, 0.97 <0.001
HF_score



    1 178 — —
    2 166 0.77 0.58, 1.01 0.064
    3 206 0.91 0.71, 1.16 0.436
1 IRR = Incidence Rate Ratio, CI = Confidence Interval

180 days poisson regression: group

Characteristic N IRR1 95% CI1 p-value
group



    BWH 274 — —
    MGH 276 0.66 0.56, 0.78 <0.001
1 IRR = Incidence Rate Ratio, CI = Confidence Interval

180 days poisson regression： Age Gender Race_Group

Characteristic N IRR1 95% CI1 p-value
group



    BWH 274 — —
    MGH 276 0.65 0.55, 0.76 <0.001
Age 551 0.99 0.98, 0.99 <0.001
Gender



    Female 228 — —
    Male 322 1.02 0.86, 1.22 0.782
Race_Group



    White 345 — —
    Asian 26 1.17 0.76, 1.71 0.458
    Black 106 1.47 1.20, 1.80 <0.001
    Other 72 1.14 0.88, 1.47 0.314
1 IRR = Incidence Rate Ratio, CI = Confidence Interval

180 days poisson regression： group+ Age+Gender+Race_Group+HTN+DM+CAD+Dialysis_Vintage+HF_score

Characteristic N IRR1 95% CI1 p-value
group



    BWH 274 — —
    MGH 276 0.64 0.54, 0.75 <0.001
Age 551 0.99 0.98, 0.99 <0.001
Gender



    Female 228 — —
    Male 322 1.05 0.88, 1.25 0.596
Race_Group



    White 345 — —
    Asian 26 1.11 0.72, 1.63 0.612
    Black 106 1.46 1.19, 1.80 <0.001
    Other 72 1.14 0.87, 1.47 0.326
HTN



    N 11 — —
    Y 539 0.69 0.42, 1.23 0.177
DM



    N 124 — —
    Y 427 0.95 0.76, 1.19 0.639
CAD



    N 66 — —
    Y 484 1.01 0.78, 1.33 0.930
Dialysis_Vintage 551 0.93 0.90, 0.96 <0.001
HF_score



    1 178 — —
    2 166 0.85 0.68, 1.05 0.140
    3 206 0.94 0.77, 1.14 0.524
1 IRR = Incidence Rate Ratio, CI = Confidence Interval

Univariate logistic regression outcome Binary Outcome is 1 or more versus 0: more_vs_zero_90days

Characteristic N OR1 95% CI1 p-value
group 551


    BWH
— —
    MGH
0.56 0.40, 0.79 <0.001
Age 551 0.99 0.97, 1.00 0.045
Gender 551


    Female
— —
    Male
1.20 0.85, 1.69 0.292
Race_Group 551


    White
— —
    Asian
0.85 0.37, 1.87 0.689
    Black
1.51 0.97, 2.34 0.066
    Other
0.94 0.56, 1.57 0.821
HTN 551


    N
— —
    Y
1.14 0.35, 3.94 0.824
DM 551


    N
— —
    Y
1.15 0.77, 1.73 0.489
CAD 551


    N
— —
    Y
0.90 0.54, 1.50 0.680
Dialysis_Vintage 551 0.91 0.86, 0.96 <0.001
HF_score 551


    1
— —
    2
0.80 0.52, 1.22 0.308
    3
0.90 0.60, 1.35 0.614
weight.ATE 551 0.90 0.77, 1.05 0.182
1 OR = Odds Ratio, CI = Confidence Interval

Multivariate logistic regression outcome Binary Outcome is 1 or more versus: 0 more_vs_zero_90days

Characteristic N OR1 95% CI1 p-value
group



    BWH 274 — —
    MGH 276 0.52 0.37, 0.74 <0.001
Age 551 0.99 0.98, 1.01 0.213
Gender



    Female 228 — —
    Male 322 1.26 0.87, 1.84 0.218
Race_Group



    White 345 — —
    Asian 26 0.88 0.38, 2.00 0.763
    Black 106 1.37 0.85, 2.23 0.200
    Other 72 0.93 0.54, 1.60 0.798
HTN



    N 11 — —
    Y 539 1.06 0.31, 3.76 0.930
DM



    N 124 — —
    Y 427 0.94 0.59, 1.48 0.782
CAD



    N 66 — —
    Y 484 0.93 0.52, 1.67 0.806
Dialysis_Vintage 551 0.91 0.86, 0.95 <0.001
HF_score



    1 178 — —
    2 166 0.77 0.49, 1.22 0.266
    3 206 0.79 0.51, 1.21 0.283
1 OR = Odds Ratio, CI = Confidence Interval

Univariate logistic regression outcome Binary Outcome is 1 or more versus: 0 more_vs_zero_180days

Characteristic N OR1 95% CI1 p-value
group 551


    BWH
— —
    MGH
0.68 0.49, 0.96 0.026
Age 551 0.99 0.98, 1.00 0.196
Gender 551


    Female
— —
    Male
0.90 0.64, 1.26 0.524
Race_Group 551


    White
— —
    Asian
1.18 0.54, 2.63 0.684
    Black
1.42 0.92, 2.22 0.117
    Other
0.75 0.45, 1.25 0.272
HTN 551


    N
— —
    Y
0.45 0.11, 1.48 0.211
DM 551


    N
— —
    Y
1.31 0.88, 1.96 0.184
CAD 551


    N
— —
    Y
1.01 0.60, 1.69 0.966
Dialysis_Vintage 551 0.91 0.86, 0.95 <0.001
HF_score 551


    1
— —
    2
0.79 0.52, 1.20 0.270
    3
1.00 0.67, 1.50 0.989
weight.ATE 551 0.84 0.72, 0.98 0.033
1 OR = Odds Ratio, CI = Confidence Interval

Multivariate logistic regression outcome Binary Outcome is 1 or more versus: 0 more_vs_zero_180days

Characteristic N OR1 95% CI1 p-value
group



    BWH 274 — —
    MGH 276 0.63 0.45, 0.89 0.009
Age 551 0.99 0.98, 1.01 0.394
Gender



    Female 228 — —
    Male 322 0.86 0.59, 1.24 0.419
Race_Group



    White 345 — —
    Asian 26 1.24 0.55, 2.84 0.612
    Black 106 1.41 0.87, 2.30 0.168
    Other 72 0.66 0.38, 1.14 0.140
HTN



    N 11 — —
    Y 539 0.44 0.10, 1.49 0.209
DM



    N 124 — —
    Y 427 1.12 0.71, 1.76 0.632
CAD



    N 66 — —
    Y 484 1.05 0.59, 1.89 0.864
Dialysis_Vintage 551 0.91 0.86, 0.95 <0.001
HF_score



    1 178 — —
    2 166 0.80 0.51, 1.26 0.337
    3 206 0.89 0.58, 1.37 0.608
1 OR = Odds Ratio, CI = Confidence Interval

Univariate coxph decongestion_time_days

Characteristic N HR1 95% CI1 p-value
group 551


    BWH
— —
    MGH
1.63 1.25, 2.12 <0.001
Age 551 1.00 0.99, 1.01 0.485
Gender 551


    Female
— —
    Male
1.00 0.77, 1.28 0.976
Race_Group 551


    White
— —
    Asian
1.64 1.07, 2.49 0.022
    Black
1.30 0.95, 1.78 0.100
    Other
1.35 0.94, 1.94 0.104
HTN 551


    N
— —
    Y
1.19 0.61, 2.33 0.611
DM 551


    N
— —
    Y
0.73 0.53, 1.00 0.047
CAD 551


    N
— —
    Y
0.71 0.54, 0.92 0.011
Dialysis_Vintage 551 1.03 1.01, 1.06 0.003
HF_score 551


    1
— —
    2
1.02 0.77, 1.34 0.916
    3
0.74 0.54, 1.02 0.066
LOS 551 0.95 0.94, 0.97 <0.001
weight.ATE 551 1.05 0.88, 1.25 0.594
1 HR = Hazard Ratio, CI = Confidence Interval

coxph decongestion_time_days Multivariate regression: age gender race

Characteristic HR1 95% CI1 p-value
group


    BWH — —
    MGH 1.65 1.27, 2.13 <0.001
Age 1.01 1.00, 1.02 0.238
Gender


    Female — —
    Male 1.06 0.81, 1.38 0.681
Race_Group


    White — —
    Asian 1.53 1.01, 2.32 0.043
    Black 1.42 1.01, 1.98 0.041
    Other 1.36 0.90, 2.07 0.148
1 HR = Hazard Ratio, CI = Confidence Interval

coxph decongestion_time_days Multivariate regression:group+ Age+Gender+Race_Group+HTN+DM+CAD+Dialysis_Vintage+HF_score

Characteristic HR1 95% CI1 p-value
group


    BWH — —
    MGH 1.61 1.26, 2.07 <0.001
Age 1.01 1.00, 1.02 0.148
Gender


    Female — —
    Male 1.10 0.85, 1.42 0.473
Race_Group


    White — —
    Asian 1.54 1.03, 2.32 0.037
    Black 1.33 0.95, 1.84 0.095
    Other 1.40 0.93, 2.09 0.104
HTN


    N — —
    Y 1.05 0.54, 2.01 0.889
DM


    N — —
    Y 0.81 0.60, 1.08 0.143
CAD


    N — —
    Y 0.80 0.58, 1.09 0.153
Dialysis_Vintage 1.03 1.00, 1.06 0.059
HF_score


    1 — —
    2 1.01 0.75, 1.36 0.966
    3 0.80 0.58, 1.12 0.198
1 HR = Hazard Ratio, CI = Confidence Interval

Competing risk 1st_readmission_180

##      Estimate   Robust SE z-value    p-value   Hazard Ratio
## [1,] "$-0.326$" "$0.188$" "$-1.732$" "$0.083$" "$0.722$"   
##      95\\% CI            
## [1,] "($0.499$, $1.044$)"

Univariate coxph time_1st_readmission_180

Characteristic N HR1 95% CI1 p-value
group 551 0.74 0.51, 1.07 0.109
Age 551 0.99 0.98, 1.01 0.206
Gender 551


    Female
— —
    Male
1.05 0.73, 1.51 0.808
Race_Group 551


    White
— —
    Asian
1.22 0.60, 2.49 0.580
    Black
1.41 0.90, 2.20 0.134
    Other
1.06 0.59, 1.90 0.843
HTN 551


    N
— —
    Y
0.67 0.31, 1.48 0.325
DM 551


    N
— —
    Y
1.25 0.79, 1.97 0.339
CAD 551


    N
— —
    Y
0.92 0.55, 1.52 0.740
Dialysis_Vintage 551 0.95 0.91, 0.99 0.013
HF_score 551


    1
— —
    2
0.84 0.52, 1.34 0.452
    3
1.07 0.70, 1.65 0.754
HD_Unit 551


    No
— —
    Yes
1.04 0.61, 1.77 0.899
weight.ATE 551 0.93 0.75, 1.16 0.507
1 HR = Hazard Ratio, CI = Confidence Interval

coxph time_1st_readmission_180 Multivariate linear regression los: age gender race

Characteristic HR1 95% CI1 p-value
group 0.73 0.51, 1.05 0.091
Age 0.99 0.98, 1.01 0.302
Gender


    Female — —
    Male 1.03 0.71, 1.50 0.877
Race_Group


    White — —
    Asian 1.28 0.61, 2.70 0.512
    Black 1.35 0.86, 2.11 0.189
    Other 1.07 0.59, 1.94 0.820
1 HR = Hazard Ratio, CI = Confidence Interval

coxph time_1st_readmission_180 Multivariate linear regression:group+ Age+Gender+Race_Group+HTN+DM+CAD+Dialysis_Vintage+HF_score

Characteristic HR1 95% CI1 p-value
group 0.70 0.49, 1.02 0.062
Age 0.99 0.98, 1.01 0.361
Gender


    Female — —
    Male 1.08 0.72, 1.62 0.699
Race_Group


    White — —
    Asian 1.24 0.56, 2.73 0.595
    Black 1.35 0.86, 2.13 0.188
    Other 1.06 0.57, 1.94 0.863
HTN


    N — —
    Y 0.61 0.26, 1.44 0.263
DM


    N — —
    Y 1.12 0.69, 1.82 0.642
CAD


    N — —
    Y 0.90 0.52, 1.56 0.709
Dialysis_Vintage 0.95 0.91, 0.99 0.015
HF_score


    1 — —
    2 0.86 0.51, 1.44 0.564
    3 1.01 0.62, 1.63 0.982
1 HR = Hazard Ratio, CI = Confidence Interval

decongestion_time_days,n_90,n_180,time_1st_readmission_180

1
(N=118)		 2
(N=160)		 Overall
(N=278)
decongestion_time_days
Mean (SD) 2.70 (3.21) 1.49 (1.79) 2.00 (2.56)
Median [Q1,Q3] 2.00 [0.250,3.75] 1.00 [0,2.00] 2.00 [0,3.00]
n_90
Mean (SD) 0.847 (0.975) 0.506 (0.785) 0.651 (0.885)
Median [Q1,Q3] 1.00 [0,1.00] 0 [0,1.00] 0 [0,1.00]
n_180
Mean (SD) 1.36 (1.63) 0.763 (1.08) 1.01 (1.37)
Median [Q1,Q3] 1.00 [0,2.00] 0 [0,1.00] 1.00 [0,1.00]
time_1st_readmission_180
Mean (SD) 99.7 (74.1) 122 (70.4) 113 (72.7)
Median [Q1,Q3] 88.5 [26.3,180] 180 [46.3,180] 169 [33.5,180]

HR Time to decongestion Multivariate model