| Characteristic | Overall N = 2311 |
Amyloid cardiomyopathy N = 1191 |
Hypertensive organ damage (no CMP) N = 301 |
Hypertrophic cardiomyopathy N = 821 |
p-value2 |
|---|---|---|---|---|---|
| Systolic.Blood.Pressure..mmHg. | 130 (110, 144) | 120 (110, 140) | 140 (125, 160) | 130 (115, 148) | <0.001 |
| Diastolic.Blood.Pressure..mmHg. | 70 (65, 80) | 70 (65, 80) | 80 (73, 90) | 75 (70, 85) | <0.001 |
| NYHA.Class | <0.001 | ||||
| Class I | 106 (48%) | 32 (28%) | 19 (66%) | 55 (71%) | |
| Class II | 66 (30%) | 43 (38%) | 7 (24%) | 16 (21%) | |
| Class III | 45 (20%) | 36 (32%) | 3 (10%) | 6 (7.8%) | |
| Class IV | 3 (1.4%) | 3 (2.6%) | 0 (0%) | 0 (0%) | |
| Heart.Rate..bpm. | 70 (60, 82) | 75 (63, 85) | 67 (61, 75) | 66 (59, 80) | 0.008 |
| PR.Interval..ms. | 180 (160, 210) | 200 (160, 226) | 172 (150, 200) | 166 (146, 190) | 0.001 |
| QRS.Duration..ms. | 100 (80, 120) | 100 (80, 130) | 95 (90, 128) | 90 (80, 120) | 0.7 |
| QTc.Interval..ms. | 439 (410, 463) | 447 (416, 468) | 421 (383, 447) | 433 (402, 454) | 0.025 |
| Q.Waves | 19 (8.2%) | 8 (6.7%) | 2 (6.7%) | 9 (11%) | 0.6 |
| ST.Segment.Abnormalities | 12 (5.2%) | 6 (5.0%) | 1 (3.4%) | 5 (6.1%) | >0.9 |
| Left.Ventricular.Hypertrophy | 34 (15%) | 4 (3.4%) | 1 (3.3%) | 29 (35%) | <0.001 |
| Right.Ventricular.Hypertrophy | |||||
| No | 231 (100%) | 119 (100%) | 30 (100%) | 82 (100%) | |
| Low.QRS.Voltage | 29 (14%) | 24 (22%) | 2 (7.4%) | 3 (4.4%) | 0.002 |
| Hemoglobin..g.l. | 13.35 (11.90, 14.70) | 12.65 (11.10, 14.00) | 13.70 (12.50, 14.30) | 14.55 (12.80, 15.20) | <0.001 |
| Creatinine..mg.dl. | 1.10 (0.94, 1.40) | 1.23 (1.00, 1.56) | 1.31 (0.99, 1.60) | 0.99 (0.85, 1.16) | <0.001 |
| eGFR..ml.min.1.73m2. | 75 (53, 90) | 63 (47, 86) | 62 (49, 81) | 85 (73, 106) | <0.001 |
| K...mEq.l. | 4.30 (4.00, 4.70) | 4.40 (4.00, 4.70) | 4.20 (4.00, 4.80) | 4.30 (3.90, 4.70) | 0.7 |
| Troponin.I.high.sensitivity..ng.l. | 58 (28, 143) | 79 (45, 151) | 38 (19, 38) | 35 (17, 232) | 0.3 |
| BNP..ng.l. | 437 (223, 656) | 486 (274, 756) | 223 (189, 256) | 77 (60, 521) | 0.11 |
| NT.pro.BNP..ng.l. | 1,909 (694, 3,863) | 2,357 (1,532, 4,804) | 664 (84, 1,650) | 693 (458, 1,228) | 0.001 |
| IVS.Diastole..mm. | 17.0 (15.0, 20.0) | 18.0 (15.0, 20.0) | 15.0 (13.0, 16.0) | 18.0 (15.0, 20.0) | <0.001 |
| LV.Diameter.Diastole..mm. | 45 (41, 48) | 43 (39, 47) | 46 (43, 51) | 45 (41, 48) | 0.035 |
| LVPW.Diastole..mm. | 13.0 (11.0, 15.0) | 14.5 (12.0, 17.5) | 11.0 (9.0, 12.0) | 12.0 (10.0, 14.0) | <0.001 |
| iLVEDV..ml.m2. | 47 (40, 55) | 47 (40, 53) | 52 (47, 64) | 46 (39, 54) | 0.033 |
| iLVESV..ml.m2. | 20 (16, 28) | 23 (17, 27) | 21 (16, 33) | 17 (14, 26) | 0.2 |
| LVEF.... | 58 (50, 65) | 55 (45, 60) | 60 (55, 65) | 63 (59, 67) | <0.001 |
| iSV..ml.m2. | 68 (60, 90) | 65 (56, 72) | 90 (67, 116) | 74 (61, 99) | 0.013 |
| iLAV..ml.m2. | 41 (31, 50) | 43 (36, 53) | 32 (28, 38) | 39 (28, 50) | <0.001 |
| iRAV..ml.m2. | 25 (18, 36) | 33 (24, 44) | 21 (19, 27) | 21 (15, 29) | <0.001 |
| Mitral.E..m.s. | 0.83 (0.64, 1.00) | 0.99 (0.75, 1.00) | 0.73 (0.61, 1.00) | 0.64 (0.57, 1.00) | 0.040 |
| Lateral.Mitral.E...m.s. | 0.06 (0.05, 0.08) | 0.05 (0.04, 0.07) | 0.08 (0.06, 0.09) | 0.08 (0.06, 0.10) | 0.001 |
| Septal.Mitral.E...m.s. | 0.050 (0.040, 0.060) | 0.040 (0.035, 0.050) | 0.068 (0.048, 0.080) | 0.050 (0.050, 0.060) | 0.012 |
| Mitral.E.E..Ratio | 14 (9, 18) | 17 (14, 22) | 10 (8, 13) | 10 (8, 14) | <0.001 |
| LV.Outflow.Tract.Obstruction | 27 (23%) | 0 (0%) | 1 (13%) | 26 (35%) | <0.001 |
| LVOT.Basal.Gradient..mmHg. | 37 (14, 75) | NA (NA, NA) | 75 (75, 75) | 36 (14, 67) | 0.3 |
| LVOT.Dynamic.Gradient..mmHg. | 67 (35, 88) | NA (NA, NA) | 75 (75, 75) | 66 (31, 90) | 0.6 |
| TAPSE..mm. | 20 (17, 24) | 17 (16, 20) | 21 (19, 23) | 23 (20, 25) | <0.001 |
| S...m.s. | 0.1 (0.1, 0.1) | 0.1 (0.1, 0.1) | 0.1 (0.1, 0.2) | 0.1 (0.1, 0.1) | 0.14 |
| FAC.... | 40 (32, 40) | 38 (29, 40) | NA (NA, NA) | 44 (40, 51) | 0.005 |
| RV.Basal.Diameter..mm. | 36 (33, 39) | 37 (34, 40) | 36 (33, 40) | 35 (31, 38) | 0.014 |
| Tricuspid.Regurgitation.V.Max..m.s. | 2.75 (2.50, 3.00) | 2.80 (2.50, 3.06) | 2.55 (2.55, 2.55) | 2.23 (2.23, 2.23) | 0.3 |
| Inferior.Vena.Cava.Diameter..mm. | 17 (15, 20) | 18 (15, 22) | 17 (15, 18) | 17 (15, 18) | 0.011 |
| Inferior.Vena.Cava.Collapsibility.... | 70 (60, 80) | 70 (30, 80) | 80 (70, 100) | 70 (70, 80) | <0.001 |
| sPAP..mmHg. | 33 (27, 40) | 37 (30, 45) | 30 (26, 35) | 30 (25, 37) | <0.001 |
| LV.Global.Longitudinal.Strain.... | -14.5 (-17.0, -12.0) | -13.0 (-16.0, -10.0) | -15.4 (-17.0, -13.8) | -15.8 (-19.7, -13.3) | 0.7 |
| 1 Median (Q1, Q3); n (%) | |||||
| 2 Kruskal-Wallis rank sum test; Fisher’s exact test | |||||