TEDD Activity and Sleep Longitudinal Summary 10-24-24
Karl Brown
2024-10-24
## `summarise()` has grouped output by 'newID'. You can override using the
## `.groups` argument.
Baseline summary
| DLB (N=11) |
AD (N=10) |
P-value | |
|---|---|---|---|
| Daily activity counts (millions) | |||
| Mean (SD) | 1.24 (0.473) | 1.62 (0.211) | 0.031 |
| Median [Min, Max] | 1.37 [0.407, 1.86] | 1.62 [1.29, 1.95] | |
| Hours in REM | |||
| Mean (SD) | 0.300 (0.309) | 1.03 (0.389) | <0.001 |
| Median [Min, Max] | 0.190 [0, 0.720] | 0.900 [0.550, 1.59] | |
| Missing | 3 (27.3%) | 1 (10.0%) | |
| REM % | |||
| Mean (SD) | 6.24 (7.31) | 17.0 (4.58) | 0.004 |
| Median [Min, Max] | 3.00 [0, 19.5] | 17.6 [9.03, 22.5] | |
| Missing | 3 (27.3%) | 1 (10.0%) | |
| Hours in NRH | |||
| Mean (SD) | 0.830 (0.690) | 0.216 (0.237) | 0.042 |
| Median [Min, Max] | 0.760 [0, 2.30] | 0.155 [0, 0.635] | |
| Missing | 3 (27.3%) | 1 (10.0%) | |
| NRH % | |||
| Mean (SD) | 14.7 (11.2) | 3.77 (4.44) | 0.029 |
| Median [Min, Max] | 13.2 [0, 37.3] | 2.20 [0, 11.7] | |
| Missing | 3 (27.3%) | 1 (10.0%) | |
| Sleep efficiency | |||
| Mean (SD) | 71.6 (16.9) | 75.4 (9.94) | 0.584 |
| Median [Min, Max] | 74.0 [36.7, 90.7] | 74.6 [62.1, 91.2] | |
| Missing | 3 (27.3%) | 1 (10.0%) | |
| AAI | |||
| Mean (SD) | 13.0 (11.9) | 43.7 (27.3) | 0.016 |
| Median [Min, Max] | 7.20 [3.20, 34.9] | 44.4 [8.40, 80.1] | |
| Missing | 3 (27.3%) | 2 (20.0%) | |
| Spindle | |||
| Mean (SD) | 6.00 (13.3) | 5.96 (13.9) | 0.995 |
| Median [Min, Max] | 0.0500 [0, 37.8] | 0.300 [0, 42.7] | |
| Missing | 3 (27.3%) | 1 (10.0%) | |
| AN3 | |||
| Mean (SD) | 5.86 (6.28) | 2.47 (4.91) | 0.24 |
| Median [Min, Max] | 3.05 [0.300, 15.4] | 0.700 [0, 15.4] | |
| Missing | 3 (27.3%) | 1 (10.0%) | |
| N1 % | |||
| Mean (SD) | 4.00 (2.34) | 7.17 (5.86) | 0.164 |
| Median [Min, Max] | 3.46 [0.688, 7.70] | 3.43 [2.61, 18.1] | |
| Missing | 3 (27.3%) | 1 (10.0%) | |
| N2 % | |||
| Mean (SD) | 55.9 (22.9) | 58.5 (21.2) | 0.812 |
| Median [Min, Max] | 63.2 [14.3, 79.4] | 62.9 [19.9, 79.9] | |
| Missing | 3 (27.3%) | 1 (10.0%) | |
| N3 % | |||
| Mean (SD) | 19.7 (26.9) | 13.6 (20.2) | 0.612 |
| Median [Min, Max] | 6.55 [0.500, 73.1] | 3.87 [0.500, 49.2] | |
| Missing | 3 (27.3%) | 1 (10.0%) |
6 month summary
| DLB (N=9) |
AD (N=9) |
P-value | |
|---|---|---|---|
| Daily activity counts (millions) | |||
| Mean (SD) | 1.08 (0.311) | 1.60 (0.203) | 0.001 |
| Median [Min, Max] | 1.13 [0.532, 1.46] | 1.58 [1.33, 1.94] | |
| Missing | 0 (0%) | 1 (11.1%) | |
| Hours in REM | |||
| Mean (SD) | 0.346 (0.486) | 1.04 (0.416) | 0.008 |
| Median [Min, Max] | 0.130 [0, 1.48] | 1.03 [0.370, 1.70] | |
| Missing | 0 (0%) | 2 (22.2%) | |
| REM % | |||
| Mean (SD) | 5.73 (7.63) | 17.7 (7.20) | 0.007 |
| Median [Min, Max] | 2.41 [0, 23.8] | 18.3 [4.83, 28.3] | |
| Missing | 0 (0%) | 2 (22.2%) | |
| Hours in NRH | |||
| Mean (SD) | 1.15 (0.819) | 0.248 (0.223) | 0.011 |
| Median [Min, Max] | 1.19 [0, 2.32] | 0.259 [0, 0.645] | |
| Missing | 0 (0%) | 2 (22.2%) | |
| NRH % | |||
| Mean (SD) | 18.6 (10.7) | 4.43 (4.81) | 0.004 |
| Median [Min, Max] | 21.2 [0, 31.8] | 3.30 [0, 14.2] | |
| Missing | 0 (0%) | 2 (22.2%) | |
| Sleep efficiency | |||
| Mean (SD) | 74.5 (21.0) | 74.9 (7.47) | 0.961 |
| Median [Min, Max] | 78.4 [25.9, 94.0] | 76.3 [62.6, 86.2] | |
| Missing | 0 (0%) | 2 (22.2%) | |
| AAI | |||
| Mean (SD) | 14.4 (12.3) | 38.8 (34.1) | 0.113 |
| Median [Min, Max] | 13.4 [2.30, 35.1] | 29.8 [2.10, 86.7] | |
| Missing | 0 (0%) | 2 (22.2%) | |
| Spindle | |||
| Mean (SD) | 5.03 (12.9) | 5.03 (11.3) | 0.999 |
| Median [Min, Max] | 0.100 [0, 39.0] | 0.200 [0, 30.4] | |
| Missing | 0 (0%) | 2 (22.2%) | |
| AN3 | |||
| Mean (SD) | 6.40 (8.01) | 1.89 (4.01) | 0.167 |
| Median [Min, Max] | 3.40 [0, 22.0] | 0.100 [0, 10.8] | |
| Missing | 0 (0%) | 2 (22.2%) | |
| N1 % | |||
| Mean (SD) | 6.27 (3.68) | 7.61 (6.85) | 0.653 |
| Median [Min, Max] | 7.55 [0.400, 10.5] | 5.49 [1.83, 20.3] | |
| Missing | 0 (0%) | 2 (22.2%) | |
| N2 % | |||
| Mean (SD) | 49.8 (21.3) | 55.2 (23.5) | 0.645 |
| Median [Min, Max] | 61.0 [12.8, 76.9] | 64.2 [22.9, 84.6] | |
| Missing | 0 (0%) | 2 (22.2%) | |
| N3 % | |||
| Mean (SD) | 18.0 (23.2) | 8.15 (13.8) | 0.311 |
| Median [Min, Max] | 8.84 [1.30, 64.8] | 1.63 [0.107, 38.5] | |
| Missing | 0 (0%) | 2 (22.2%) |
1 year summary
| DLB (N=7) |
AD (N=6) |
P-value | |
|---|---|---|---|
| Daily activity counts (millions) | |||
| Mean (SD) | 1.18 (0.357) | 1.53 (0.150) | 0.048 |
| Median [Min, Max] | 1.06 [0.741, 1.75] | 1.54 [1.36, 1.69] | |
| Missing | 0 (0%) | 1 (16.7%) | |
| Hours in REM | |||
| Mean (SD) | 0.438 (0.357) | 1.05 (0.329) | 0.012 |
| Median [Min, Max] | 0.570 [0, 0.760] | 1.03 [0.530, 1.46] | |
| Missing | 1 (14.3%) | 0 (0%) | |
| REM % | |||
| Mean (SD) | 7.22 (5.11) | 17.2 (6.80) | 0.016 |
| Median [Min, Max] | 9.12 [0, 12.8] | 14.9 [10.6, 26.1] | |
| Hours in NRH | |||
| Mean (SD) | 1.57 (1.04) | 0.269 (0.163) | 0.027 |
| Median [Min, Max] | 1.51 [0.260, 2.93] | 0.299 [0, 0.450] | |
| Missing | 1 (14.3%) | 0 (0%) | |
| NRH % | |||
| Mean (SD) | 22.8 (19.1) | 4.30 (2.71) | 0.064 |
| Median [Min, Max] | 18.7 [5.80, 58.6] | 4.30 [0, 8.50] | |
| Missing | 1 (14.3%) | 0 (0%) | |
| Sleep efficiency | |||
| Mean (SD) | 76.6 (11.7) | 68.9 (10.8) | 0.264 |
| Median [Min, Max] | 77.3 [60.3, 88.6] | 73.5 [50.3, 78.0] | |
| Missing | 1 (14.3%) | 0 (0%) | |
| AAI | |||
| Mean (SD) | 8.60 (5.99) | 31.5 (32.5) | 0.146 |
| Median [Min, Max] | 7.85 [1.10, 18.3] | 20.1 [1.40, 74.4] | |
| Missing | 1 (14.3%) | 0 (0%) | |
| Spindle | |||
| Mean (SD) | 1.08 (2.23) | 1.13 (2.48) | 0.971 |
| Median [Min, Max] | 0.100 [0, 5.60] | 0.150 [0, 6.20] | |
| Missing | 1 (14.3%) | 0 (0%) | |
| AN3 | |||
| Mean (SD) | 7.62 (8.22) | 2.15 (2.67) | 0.172 |
| Median [Min, Max] | 5.10 [0.600, 23.4] | 1.10 [0.500, 7.50] | |
| Missing | 1 (14.3%) | 0 (0%) | |
| N1 % | |||
| Mean (SD) | 4.80 (5.64) | 9.72 (4.70) | 0.115 |
| Median [Min, Max] | 2.79 [0.348, 16.8] | 10.7 [3.26, 15.1] | |
| N2 % | |||
| Mean (SD) | 46.7 (23.4) | 60.9 (14.5) | 0.214 |
| Median [Min, Max] | 58.7 [16.8, 74.0] | 65.8 [36.7, 73.9] | |
| N3 % | |||
| Mean (SD) | 22.5 (21.6) | 7.47 (13.8) | 0.159 |
| Median [Min, Max] | 13.4 [0.801, 57.3] | 2.14 [0.146, 35.4] |
Baseline boxplot
Activity
REM
non-REM hypertonia
Night/day ratio plot
