| Ultralow (N=9) |
Low (N=51) |
High1 (N=333) |
High2 (N=210) |
Overall (N=603) |
P-value | |
|---|---|---|---|---|---|---|
| Age | ||||||
| <50 | 6 (66.7%) | 20 (39.2%) | 119 (35.7%) | 85 (40.5%) | 230 (38.1%) | 0.399 |
| >=50 | 3 (33.3%) | 30 (58.8%) | 213 (64.0%) | 124 (59.0%) | 370 (61.4%) | |
| Unknown | 0 (0%) | 1 (2.0%) | 1 (0.3%) | 1 (0.5%) | 3 (0.5%) | |
| Menopausal Status | ||||||
| NA-query | 0 (0%) | 0 (0%) | 5 (1.5%) | 3 (1.4%) | 8 (1.3%) | 0.993 |
| Not applicable | 1 (11.1%) | 1 (2.0%) | 11 (3.3%) | 6 (2.9%) | 19 (3.2%) | |
| Post- | 5 (55.6%) | 26 (51.0%) | 189 (56.8%) | 124 (59.0%) | 344 (57.0%) | |
| Pre-/Peri- | 3 (33.3%) | 23 (45.1%) | 120 (36.0%) | 72 (34.3%) | 218 (36.2%) | |
| Unknown | 0 (0%) | 1 (2.0%) | 8 (2.4%) | 5 (2.4%) | 14 (2.3%) | |
| Race/Ethnicity | ||||||
| AAPI | 0 (0%) | 0 (0%) | 7 (2.1%) | 5 (2.4%) | 12 (2.0%) | 0.983 |
| American Indian or Alaska Native | 0 (0%) | 0 (0%) | 1 (0.3%) | 0 (0%) | 1 (0.2%) | |
| Black | 3 (33.3%) | 5 (9.8%) | 44 (13.2%) | 32 (15.2%) | 84 (13.9%) | |
| Latin American | 0 (0%) | 3 (5.9%) | 18 (5.4%) | 12 (5.7%) | 33 (5.5%) | |
| Mixed | 0 (0%) | 1 (2.0%) | 2 (0.6%) | 1 (0.5%) | 4 (0.7%) | |
| NA-query | 0 (0%) | 0 (0%) | 1 (0.3%) | 0 (0%) | 1 (0.2%) | |
| Unknown | 1 (11.1%) | 3 (5.9%) | 20 (6.0%) | 18 (8.6%) | 42 (7.0%) | |
| White | 5 (55.6%) | 39 (76.5%) | 240 (72.1%) | 142 (67.6%) | 426 (70.6%) | |
| Tumor Stage | ||||||
| discordant-query | 0 (0%) | 0 (0%) | 1 (0.4%) | 1 (0.6%) | 2 (0.4%) | 0.0045 |
| T1 | 1 (14.3%) | 2 (5.7%) | 62 (23.3%) | 38 (23.0%) | 103 (21.8%) | |
| T2 | 2 (28.6%) | 16 (45.7%) | 137 (51.5%) | 100 (60.6%) | 255 (53.9%) | |
| T3 | 2 (28.6%) | 15 (42.9%) | 51 (19.2%) | 15 (9.1%) | 83 (17.5%) | |
| T4 | 2 (28.6%) | 2 (5.7%) | 15 (5.6%) | 11 (6.7%) | 30 (6.3%) | |
| Lymph Node Status | ||||||
| N0 | 2 (28.6%) | 12 (34.3%) | 95 (36.0%) | 77 (47.2%) | 186 (39.7%) | 0.636 |
| N1 | 5 (71.4%) | 19 (54.3%) | 143 (54.2%) | 67 (41.1%) | 234 (49.9%) | |
| N2 | 0 (0%) | 3 (8.6%) | 9 (3.4%) | 7 (4.3%) | 19 (4.1%) | |
| N3 | 0 (0%) | 1 (2.9%) | 7 (2.7%) | 7 (4.3%) | 15 (3.2%) | |
| Not assessed | 0 (0%) | 0 (0%) | 10 (3.8%) | 5 (3.1%) | 15 (3.2%) | |
| Grade | ||||||
| discordant-query | 0 (0%) | 2 (4.0%) | 8 (2.4%) | 4 (1.9%) | 14 (2.3%) | <0.001 |
| G1 | 2 (22.2%) | 4 (8.0%) | 28 (8.5%) | 1 (0.5%) | 35 (5.9%) | |
| G2 | 7 (77.8%) | 40 (80.0%) | 176 (53.5%) | 41 (19.6%) | 264 (44.2%) | |
| G3 | 0 (0%) | 2 (4.0%) | 102 (31.0%) | 156 (74.6%) | 260 (43.6%) | |
| Unknown | 0 (0%) | 2 (4.0%) | 15 (4.6%) | 7 (3.3%) | 24 (4.0%) | |
| ER% | ||||||
| High (>50%) | 9 (100%) | 51 (100%) | 313 (95.7%) | 102 (54.3%) | 475 (82.6%) | <0.001 |
| Low (<10%) | 0 (0%) | 0 (0%) | 3 (0.9%) | 44 (23.4%) | 47 (8.2%) | |
| Medium (10-50%) | 0 (0%) | 0 (0%) | 11 (3.4%) | 42 (22.3%) | 53 (9.2%) | |
| Ki67% | ||||||
| <=20 | 3 (33.3%) | 20 (39.2%) | 63 (18.9%) | 8 (3.8%) | 94 (15.6%) | <0.001 |
| >20 | 4 (44.4%) | 14 (27.5%) | 166 (49.8%) | 145 (69.0%) | 329 (54.6%) | |
| Unknown | 2 (22.2%) | 17 (33.3%) | 104 (31.2%) | 57 (27.1%) | 180 (29.9%) | |
| Surgery Type | ||||||
| BCS | 4 (44.4%) | 13 (25.5%) | 132 (39.6%) | 100 (47.6%) | 249 (41.3%) | 0.0715 |
| Exclude | 1 (11.1%) | 2 (3.9%) | 4 (1.2%) | 1 (0.5%) | 8 (1.3%) | |
| Mastectomy | 4 (44.4%) | 35 (68.6%) | 194 (58.3%) | 108 (51.4%) | 341 (56.6%) | |
| Unknown | 0 (0%) | 1 (2.0%) | 3 (0.9%) | 1 (0.5%) | 5 (0.8%) | |
| BP Subtype | ||||||
| Basal | 0 (0%) | 0 (0%) | 8 (2.4%) | 112 (53.3%) | 120 (19.9%) | <0.001 |
| HER2 | 0 (0%) | 0 (0%) | 0 (0%) | 2 (1.0%) | 2 (0.3%) | |
| Luminal A | 9 (100%) | 49 (96.1%) | 0 (0%) | 0 (0%) | 58 (9.6%) | |
| Luminal B | 0 (0%) | 0 (0%) | 317 (95.2%) | 91 (43.3%) | 408 (67.7%) | |
| Not Requested | 0 (0%) | 2 (3.9%) | 8 (2.4%) | 5 (2.4%) | 15 (2.5%) |