Aim case matched

#Table 1

Univariate coxph hosp_outcome 30 days

Characteristic	N	HR1	95% CI1	p-value
age_bl	626	1.02	0.99, 1.04	0.162
days_last_vaccine_cat_new	626
0		—	—
0-270days		0.56	0.31, 1.03	0.063
over 270days		0.87	0.42, 1.80	0.699
Gender_Legal_Sex	626
Female		—	—
Male		0.69	0.39, 1.22	0.199
htn	626
0		—	—
1		1.33	0.68, 2.58	0.406
dm	626
0		—	—
1		1.34	0.80, 2.26	0.267
copd	626
0		—	—
1		1.28	0.59, 2.81	0.530
cad	626
0		—	—
1		1.11	0.67, 1.84	0.687
chf	626
0		—	—
1		1.03	0.40, 2.65	0.954
subclass	626	1.00	1.00, 1.01	0.419
1 HR = Hazard Ratio, CI = Confidence Interval

Multivariate coxph hosp_outcome 30 days days_last_vaccine_cat_new

Characteristic	N	HR1	95% CI1	p-value
age_bl	626	1.02	0.99, 1.04	0.189
days_last_vaccine_cat_new	626
0		—	—
0-270days		0.53	0.29, 0.97	0.041
over 270days		0.76	0.36, 1.61	0.477
Gender_Legal_Sex	626
Female		—	—
Male		0.67	0.38, 1.19	0.173
htn	626
0		—	—
1		1.16	0.58, 2.33	0.668
dm	626
0		—	—
1		1.31	0.75, 2.26	0.343
copd	626
0		—	—
1		1.10	0.47, 2.54	0.829
cad	626
0		—	—
1		1.10	0.65, 1.87	0.722
chf	626
0		—	—
1		0.82	0.29, 2.29	0.705
1 HR = Hazard Ratio, CI = Confidence Interval

Multivariate coxph hosp_outcome 30 days

Characteristic	N	HR1	95% CI1	p-value
age_bl	626	1.02	0.99, 1.04	0.189
days_last_vaccine_cat_new	626
0		—	—
0-270days		0.53	0.29, 0.97	0.041
over 270days		0.76	0.36, 1.61	0.477
Gender_Legal_Sex	626
Female		—	—
Male		0.67	0.38, 1.19	0.173
htn	626
0		—	—
1		1.16	0.58, 2.33	0.668
dm	626
0		—	—
1		1.31	0.75, 2.26	0.343
copd	626
0		—	—
1		1.10	0.47, 2.54	0.829
cad	626
0		—	—
1		1.10	0.65, 1.87	0.722
chf	626
0		—	—
1		0.82	0.29, 2.29	0.705
1 HR = Hazard Ratio, CI = Confidence Interval

Univariate coxph death 365 days

Characteristic	N	HR1	95% CI1	p-value
age_bl	626	1.06	1.03, 1.09	<0.001
days_last_vaccine_cat_new	626
0		—	—
0-270days		0.46	0.24, 0.89	0.021
over 270days		0.61	0.24, 1.54	0.297
Gender_Legal_Sex	626
Female		—	—
Male		0.87	0.47, 1.61	0.661
htn	626
0		—	—
1		1.04	0.51, 2.11	0.924
dm	626
0		—	—
1		1.31	0.71, 2.39	0.388
cad	626
0		—	—
1		1.04	0.57, 1.90	0.888
chf	626
0		—	—
1		1.07	0.36, 3.18	0.906
copd	626
0		—	—
1		1.90	0.91, 3.99	0.088
subclass	626	1.01	1.00, 1.01	0.052
1 HR = Hazard Ratio, CI = Confidence Interval

Multivariate coxph death 365 days

Characteristic	N	HR1	95% CI1	p-value
age_bl	626	1.07	1.03, 1.10	<0.001
days_last_vaccine_cat_new	626
0		—	—
0-270days		0.43	0.22, 0.86	0.017
over 270days		0.46	0.17, 1.23	0.121
Gender_Legal_Sex	626
Female		—	—
Male		0.90	0.48, 1.68	0.744
htn	626
0		—	—
1		0.69	0.30, 1.57	0.373
dm	626
0		—	—
1		1.51	0.78, 2.91	0.223
copd	626
0		—	—
1		1.72	0.82, 3.63	0.153
cad	626
0		—	—
1		0.98	0.52, 1.85	0.948
chf	626
0		—	—
1		0.77	0.28, 2.11	0.610
1 HR = Hazard Ratio, CI = Confidence Interval

Univariate coxph new_renal_outcome

Characteristic	N	HR1	95% CI1	p-value
age_bl	566	0.99	0.96, 1.02	0.440
days_last_vaccine_cat_new	566
0		—	—
0-270days		1.00	0.40, 2.47	0.996
over 270days		0.47	0.09, 2.36	0.361
Gender_Legal_Sex	566
Female		—	—
Male		0.76	0.36, 1.59	0.463
htn	566
0		—	—
1		1.30	0.50, 3.39	0.596
dm	566
0		—	—
1		1.88	0.86, 4.13	0.116
cad	566
0		—	—
1		1.32	0.61, 2.88	0.477
chf	566
0		—	—
1		1.38	0.35, 5.51	0.644
copd	566
0		—	—
1		0.34	0.05, 2.29	0.269
subclass	566	1.00	0.99, 1.01	0.642
1 HR = Hazard Ratio, CI = Confidence Interval

Multivariate coxph new_renal_outcome

Characteristic	N	HR1	95% CI1	p-value
age_bl	566	0.99	0.95, 1.02	0.414
days_last_vaccine_cat_new	566
0		—	—
0-270days		0.94	0.38, 2.35	0.898
over 270days		0.45	0.09, 2.27	0.335
Gender_Legal_Sex	566
Female		—	—
Male		0.70	0.34, 1.43	0.325
htn	566
0		—	—
1		1.01	0.30, 3.38	0.989
dm	566
0		—	—
1		1.94	0.77, 4.90	0.162
cad	566
0		—	—
1		1.42	0.58, 3.49	0.445
chf	566
0		—	—
1		1.40	0.37, 5.31	0.624
copd	566
0		—	—
1		0.27	0.04, 1.99	0.199
1 HR = Hazard Ratio, CI = Confidence Interval

Univariate coxph new_dm_outcome

## Registered S3 method overwritten by 'gdata':
##   method         from     
##   reorder.factor DescTools

## 
##  
##    Cell Contents
## |-------------------------|
## |                       N |
## | Chi-square contribution |
## |           N / Row Total |
## |           N / Col Total |
## |         N / Table Total |
## |-------------------------|
## 
##  
## Total Observations in Table:  626 
## 
##  
##                                     | matched_final$days_last_vaccine_cat_new 
## matched_final$new_dm_outcome_status |            0 |    0-270days | over 270days |    Row Total | 
## ------------------------------------|--------------|--------------|--------------|--------------|
##                                   0 |          153 |          373 |           91 |          617 | 
##                                     |        0.000 |        0.006 |        0.019 |              | 
##                                     |        0.248 |        0.605 |        0.147 |        0.986 | 
##                                     |        0.987 |        0.982 |        1.000 |              | 
##                                     |        0.244 |        0.596 |        0.145 |              | 
## ------------------------------------|--------------|--------------|--------------|--------------|
##                                   1 |            2 |            7 |            0 |            9 | 
##                                     |        0.023 |        0.432 |        1.308 |              | 
##                                     |        0.222 |        0.778 |        0.000 |        0.014 | 
##                                     |        0.013 |        0.018 |        0.000 |              | 
##                                     |        0.003 |        0.011 |        0.000 |              | 
## ------------------------------------|--------------|--------------|--------------|--------------|
##                        Column Total |          155 |          380 |           91 |          626 | 
##                                     |        0.248 |        0.607 |        0.145 |              | 
## ------------------------------------|--------------|--------------|--------------|--------------|
## 
## 

Characteristic	N	HR1	95% CI1	p-value
age_bl	626	0.98	0.94, 1.01	0.221
days_last_vaccine_cat_new	626
0		—	—
0-270days		1.43	0.29, 6.95	0.657
over 270days		0.00	0.00, 0.00	<0.001
Gender_Legal_Sex	626
Female		—	—
Male		0.80	0.21, 3.01	0.745
cad	626
0		—	—
1		1.51	0.41, 5.66	0.538
chf	626
0		—	—
1		3.92	0.82, 18.8	0.087
copd	626
0		—	—
1		0.00	0.00, 0.00	<0.001
subclass	626	1.00	0.98, 1.01	0.415
1 HR = Hazard Ratio, CI = Confidence Interval

Multivariate coxph new_dm_outcome

Characteristic	N	HR1	95% CI1	p-value
age_bl	626	0.98	0.94, 1.01	0.212
days_last_vaccine_cat_new	626
0		—	—
0-270days		1.48	0.32, 6.87	0.618
over 270days		0.00	0.00, 0.00	<0.001
Gender_Legal_Sex	626
Female		—	—
Male		0.65	0.20, 2.11	0.479
cad	626
0		—	—
1		1.52	0.37, 6.16	0.561
chf	626
0		—	—
1		5.15	0.68, 39.2	0.114
copd	626
0		—	—
1		0.00	0.00, 0.00	<0.001
1 HR = Hazard Ratio, CI = Confidence Interval

Univariate Fine & Grey model new_cv_outcome

Characteristic	N	**Fine & Grey model new_cv_outcome **
		HR1	95% CI1	p-value
age_bl	626	1.00	0.99, 1.02	0.560
days_last_vaccine_cat_new	626
0		—	—
0-270days		0.86	0.56, 1.34	0.520
over 270days		1.22	0.69, 2.18	0.500
Gender_Legal_Sex	626
Female		—	—
Male		1.05	0.73, 1.52	0.790
htn	626
0		—	—
1		1.72	1.03, 2.88	0.038
dm	626
0		—	—
1		2.11	1.44, 3.09	<0.001
copd	626
0		—	—
1		0.98	0.52, 1.82	0.940
subclass	626	1.00	1.00, 1.00	0.770
1 HR = Hazard Ratio, CI = Confidence Interval

Multivariate Fine & Grey model new_cv_outcome

Characteristic	N	HR1	95% CI1	p-value
age_bl	626	1.00	0.99, 1.02	0.935
days_last_vaccine_cat_new	626
0		—	—
0-270days		0.80	0.51, 1.25	0.322
over 270days		1.19	0.71, 1.98	0.513
Gender_Legal_Sex	626
Female		—	—
Male		1.04	0.71, 1.53	0.839
htn	626
0		—	—
1		1.37	0.82, 2.28	0.225
dm	626
0		—	—
1		2.02	1.37, 2.98	<0.001
copd	626
0		—	—
1		0.82	0.47, 1.43	0.491
1 HR = Hazard Ratio, CI = Confidence Interval