TEDD AP and Sleep
Karl Brown
2024-08-21
| AD (N=8) |
DLB (N=12) |
P-value | |
|---|---|---|---|
| % REM | |||
| Mean (SD) | 18.0 (4.02) | 6.91 (7.12) | 0.0017 |
| Median [Min, Max] | 19.0 [13.0, 22.5] | 3.40 [0, 19.5] | |
| Missing | 1 (12.5%) | 3 (25.0%) | |
| % Non-REM hypertonia | |||
| Mean (SD) | 4.76 (4.57) | 12.7 (11.3) | 0.0816 |
| Median [Min, Max] | 3.17 [0, 11.7] | 11.4 [0, 37.3] | |
| Missing | 1 (12.5%) | 3 (25.0%) | |
| Sleep efficiency | |||
| Mean (SD) | 0.740 (0.109) | 0.736 (0.165) | 0.958 |
| Median [Min, Max] | 0.723 [0.621, 0.912] | 0.793 [0.367, 0.907] | |
| Missing | 1 (12.5%) | 3 (25.0%) | |
| Number of awakenings | |||
| Mean (SD) | 4.77 (1.94) | 4.47 (2.21) | 0.776 |
| Median [Min, Max] | 4.73 [1.61, 7.10] | 3.70 [2.50, 8.40] | |
| Missing | 1 (12.5%) | 3 (25.0%) | |
| CO exposure | |||
| Mean (SD) | 0.266 (0.0378) | 0.242 (0.0448) | 0.209 |
| Median [Min, Max] | 0.268 [0.194, 0.312] | 0.242 [0.180, 0.305] | |
| NO2 exposure | |||
| Mean (SD) | 6.00 (2.34) | 5.92 (2.95) | 0.947 |
| Median [Min, Max] | 6.32 [3.06, 8.82] | 4.94 [2.13, 10.1] | |
| O3 exposure | |||
| Mean (SD) | 34.2 (1.32) | 34.4 (1.36) | 0.759 |
| Median [Min, Max] | 34.0 [32.2, 35.9] | 34.5 [32.4, 36.8] | |
| PM10 exposure | |||
| Mean (SD) | 12.2 (1.81) | 11.8 (3.19) | 0.732 |
| Median [Min, Max] | 12.9 [9.20, 14.1] | 12.1 [7.03, 17.6] | |
| PM2.5 exposure | |||
| Mean (SD) | 5.59 (0.565) | 5.49 (0.984) | 0.792 |
| Median [Min, Max] | 5.69 [4.77, 6.42] | 5.77 [3.66, 6.69] | |
| PNC exposure | |||
| Mean (SD) | 7460 (3170) | 6770 (3720) | 0.662 |
| Median [Min, Max] | 7270 [3870, 11800] | 5070 [2020, 12600] | |
| SO2 exposure | |||
| Mean (SD) | 0.683 (0.114) | 0.609 (0.185) | 0.287 |
| Median [Min, Max] | 0.640 [0.563, 0.912] | 0.553 [0.397, 1.08] |
Correlation tests for both AD and DLB
| Exposure | Correlation | Lower CI | Upper CI | p-value |
|---|---|---|---|---|
| REM | ||||
| CO | 0.44 | -0.08 | 0.77 | 0.09 |
| NO2 | 0.39 | -0.13 | 0.74 | 0.13 |
| O3 | -0.36 | -0.73 | 0.17 | 0.17 |
| PM10 | 0.21 | -0.32 | 0.64 | 0.44 |
| PM2.5 | 0.49 | -0.01 | 0.79 | 0.05 |
| PNC | 0.46 | -0.05 | 0.78 | 0.08 |
| SO2 | 0.57 | 0.10 | 0.83 | 0.02 |
| NRH | ||||
| CO | -0.41 | -0.75 | 0.10 | 0.11 |
| NO2 | -0.42 | -0.76 | 0.10 | 0.11 |
| O3 | -0.01 | -0.50 | 0.49 | 0.97 |
| PM10 | -0.23 | -0.65 | 0.30 | 0.38 |
| PM2.5 | -0.39 | -0.74 | 0.14 | 0.14 |
| PNC | -0.42 | -0.76 | 0.10 | 0.11 |
| SO2 | -0.54 | -0.82 | -0.06 | 0.03 |
Correlation tests for just AD
| Exposure | Correlation | Lower CI | Upper CI | p-value |
|---|---|---|---|---|
| REM | ||||
| CO | -0.33 | -0.87 | 0.56 | 0.47 |
| NO2 | -0.18 | -0.82 | 0.66 | 0.70 |
| O3 | -0.21 | -0.83 | 0.65 | 0.66 |
| PM10 | -0.14 | -0.81 | 0.68 | 0.76 |
| PM2.5 | 0.30 | -0.59 | 0.86 | 0.52 |
| PNC | -0.26 | -0.85 | 0.61 | 0.57 |
| SO2 | -0.60 | -0.93 | 0.28 | 0.16 |
| NRH | ||||
| CO | 0.57 | -0.32 | 0.93 | 0.18 |
| NO2 | 0.43 | -0.48 | 0.89 | 0.34 |
| O3 | 0.70 | -0.11 | 0.95 | 0.08 |
| PM10 | 0.47 | -0.43 | 0.90 | 0.28 |
| PM2.5 | -0.04 | -0.77 | 0.74 | 0.94 |
| PNC | 0.49 | -0.41 | 0.91 | 0.26 |
| SO2 | 0.04 | -0.73 | 0.77 | 0.93 |
Correlation tests for just DLB
| Exposure | Correlation | Lower CI | Upper CI | p-value |
|---|---|---|---|---|
| REM | ||||
| CO | 0.47 | -0.28 | 0.86 | 0.20 |
| NO2 | 0.58 | -0.14 | 0.90 | 0.10 |
| O3 | -0.41 | -0.84 | 0.35 | 0.27 |
| PM10 | 0.26 | -0.49 | 0.79 | 0.49 |
| PM2.5 | 0.58 | -0.13 | 0.90 | 0.10 |
| PNC | 0.62 | -0.07 | 0.91 | 0.07 |
| SO2 | 0.82 | 0.34 | 0.96 | 0.01 |
| NRH | ||||
| CO | -0.59 | -0.90 | 0.13 | 0.10 |
| NO2 | -0.62 | -0.91 | 0.08 | 0.08 |
| O3 | -0.32 | -0.81 | 0.44 | 0.41 |
| PM10 | -0.31 | -0.81 | 0.44 | 0.41 |
| PM2.5 | -0.40 | -0.84 | 0.36 | 0.28 |
| PNC | -0.60 | -0.91 | 0.10 | 0.09 |
| SO2 | -0.61 | -0.91 | 0.09 | 0.08 |
