Table 1: Data reconstruction

Table 2. Unweighted Normal Ranges of Clinical Laboratory Tests by Sex and Race/Ethnicity
Laboratory Test % Missing NHANES Reference All Male Female
Low High Low High White Low White High Black Low Black High Hispanic Low Hispanic High Asian Low Asian High White Low White High Black Low Black High Hispanic Low Hispanic High Asian Low Asian High
Albumin, g/dL 5.98 3.70 4.70 3.65 5.10 3.51 4.91 3.57 4.98 3.55 4.93 3.47 4.84 3.54 4.91 3.57 4.98 3.55 4.93 3.47 4.84
ALT, U/L 6.11 7.00 56.00 5.00 61.00 5.00 58.00 6.00 55.00 6.00 53.00 6.00 54.00 7.00 55.00 6.00 55.00 6.00 53.00 6.00 54.00
ALP, U/L 6.01 36.00 113.00 34.00 115.00 38.00 114.00 32.00 108.00 33.00 111.00 33.00 110.00 32.00 109.00 32.00 108.00 33.00 111.00 33.00 110.00
Basophils Percent, % 3.61 0.00 0.51 0.00 0.50 0.02 0.42 0.02 0.43 0.03 0.45 0.03 0.43 0.03 0.47 0.02 0.43 0.03 0.45 0.03 0.43
Bicarbonate, mmol/L 6.08 22.00 31.00 17.00 29.00 18.00 29.00 18.00 29.00 18.00 28.00 17.00 27.00 18.00 27.00 18.00 29.00 18.00 28.00 17.00 27.00
BUN, mg/dL 5.98 6.00 23.00 6.00 21.00 6.00 22.00 6.00 22.00 5.00 20.00 6.00 21.00 5.00 20.00 6.00 22.00 5.00 20.00 6.00 21.00
Calcium, mg/dL 6.11 8.40 10.20 8.60 10.50 8.60 10.50 8.80 10.40 8.80 10.40 8.70 10.40 8.80 10.30 8.80 10.40 8.80 10.40 8.70 10.40
Chloride, meq/L 6.01 98.00 110.00 96.00 110.00 97.00 109.00 97.00 109.00 98.00 109.00 98.00 108.00 99.00 110.00 97.00 109.00 98.00 109.00 98.00 108.00
CPK, IU/L 6.08 52.00 336.00 32.00 294.00 38.00 143.00 32.00 137.00 30.00 145.00 30.00 142.00 31.00 143.00 32.00 137.00 30.00 145.00 30.00 142.00
Creatinine, mg/dL 5.98 0.67 1.17 0.47 1.10 0.73 1.45 0.67 1.45 0.68 1.25 0.68 1.24 0.50 1.27 0.67 1.45 0.68 1.25 0.68 1.24
Eosinophils Percent, % 6.11 0.00 7.20 0.00 8.40 0.00 6.80 0.00 8.10 0.00 6.70 0.00 6.70 0.00 6.60 0.00 8.10 0.00 6.70 0.00 6.70
GGT, IU/L 6.01 15.00 75.00 9.00 48.00 11.00 67.00 10.00 49.00 10.00 47.00 10.00 46.00 10.00 47.00 10.00 49.00 10.00 47.00 10.00 46.00
Globulin, g/dL 6.11 2.10 3.50 1.90 3.50 2.30 4.40 2.30 4.10 2.40 3.40 2.50 3.50 2.50 3.40 2.30 4.10 2.40 3.40 2.50 3.50
Glucose, mg/dL 6.01 74.00 106.00 67.00 105.00 68.00 108.00 67.00 109.00 67.00 109.00 68.00 108.00 67.00 110.00 67.00 109.00 67.00 109.00 68.00 108.00
Hematocrit, % 3.44 36.40 49.70 35.80 48.60 38.10 50.00 37.50 49.50 36.20 47.90 36.40 49.50 34.40 44.90 37.50 49.50 36.20 47.90 36.40 49.50
Hemoglobin, g/dL 3.44 12.90 16.00 12.50 16.70 13.70 17.50 13.30 17.20 12.80 15.80 12.90 15.80 12.30 15.60 13.30 17.20 12.80 15.80 12.90 15.80
Iron, µg/dL 5.98 45.00 170.00 37.00 145.00 47.00 192.00 39.00 147.00 36.00 146.00 38.00 146.00 38.00 159.00 39.00 147.00 36.00 146.00 38.00 146.00
LDH, IU/L 6.08 91.00 188.00 87.00 182.00 87.00 206.00 87.00 183.00 86.00 188.00 83.00 171.00 86.00 172.00 87.00 183.00 86.00 188.00 83.00 171.00
Lymphocyte Percent, % 6.11 18.60 46.80 16.80 45.00 20.40 44.70 19.60 43.10 18.30 41.70 19.30 39.00 19.50 45.10 19.60 43.10 18.30 41.70 19.30 39.00
Mean Cell Hemoglobin, pg 3.44 25.70 32.20 26.30 34.60 26.30 34.60 27.30 34.40 25.90 34.00 25.90 34.00 25.60 34.60 27.30 34.40 25.90 34.00 25.90 34.00
MCHC, g/dL 3.44 32.60 34.90 31.40 36.30 31.40 36.30 31.90 36.10 31.70 36.50 31.70 36.60 31.60 36.40 31.90 36.10 31.70 36.50 31.70 36.60
Mean Cell Volume, fL 3.44 81.40 96.40 79.80 98.90 82.90 99.30 79.80 98.90 78.90 98.90 78.80 98.60 78.90 98.70 79.80 98.90 78.90 98.90 78.80 98.60
Mean Platelet Volume, fL 6.08 7.50 12.30 8.10 12.90 8.40 12.80 8.10 12.60 7.90 12.40 7.80 12.40 7.90 12.50 8.10 12.60 7.90 12.40 7.80 12.40
Monocyte Percent, % 6.11 2.50 11.60 2.70 10.90 3.40 11.00 3.50 10.80 3.10 10.20 3.00 11.50 3.10 11.50 3.50 10.80 3.10 10.20 3.00 11.50
Osmolality, mOsm/kg 6.01 275.00 295.00 265.00 296.00 271.00 286.00 269.00 285.00 268.00 286.00 268.00 286.00 268.00 286.00 269.00 285.00 268.00 286.00 268.00 286.00
Phosphorus, mg/dL 6.11 2.50 4.90 2.50 4.90 2.50 5.40 2.40 5.30 2.40 5.20 2.40 5.10 2.40 5.10 2.40 5.30 2.40 5.20 2.40 5.10
Platelet Count, % 3.44 139.00 361.00 132.00 377.00 134.00 349.00 134.00 346.00 133.00 340.00 130.00 336.00 139.00 362.00 134.00 346.00 133.00 340.00 130.00 336.00
Potassium, meq/L 6.11 3.50 5.10 3.40 5.10 3.90 5.50 3.80 5.40 3.80 5.40 3.70 5.30 3.60 5.30 3.80 5.40 3.80 5.40 3.70 5.30
RBC, x10^6/uL 3.44 4.10 5.60 4.10 6.10 4.14 6.16 4.05 5.97 4.06 5.97 4.06 5.97 4.18 5.75 4.05 5.97 4.06 5.97 4.06 5.97
RDW, % 6.08 12.60 15.70 12.30 15.40 12.30 15.50 12.30 15.50 12.40 15.40 12.20 15.40 12.10 15.40 12.30 15.50 12.40 15.40 12.20 15.40
SNP, % 6.01 12.50 14.90 12.50 14.90 13.00 15.50 12.80 14.60 12.50 14.90 12.40 14.80 12.50 14.90 12.80 14.60 12.50 14.90 12.40 14.80
Sodium, meq/L 6.01 134.00 146.00 134.00 145.00 135.00 143.00 135.00 144.00 135.00 143.00 135.00 142.00 135.00 143.00 135.00 144.00 135.00 143.00 135.00 142.00
Total Bilirubin, mg/dL 6.08 0.20 1.20 0.20 1.24 0.29 1.33 0.25 1.21 0.21 1.14 0.20 1.13 0.21 1.18 0.25 1.21 0.21 1.14 0.20 1.13
Total Cholesterol, mg/dL 6.01 118.00 224.00 111.00 272.00 111.00 278.00 116.00 287.00 118.00 295.00 118.00 274.00 121.00 276.00 116.00 287.00 118.00 295.00 118.00 274.00
Total Protein, g/dL 6.08 6.00 8.30 5.70 8.20 5.80 8.20 5.70 8.30 5.70 8.20 5.80 8.30 6.00 8.40 5.70 8.30 5.70 8.20 5.80 8.30
Triglycerides, mg/dL 6.11 40.00 160.00 30.00 250.00 37.00 486.00 35.00 253.00 30.00 257.00 30.00 252.00 30.00 239.00 35.00 253.00 30.00 257.00 30.00 252.00
Uric Acid, mg/dL 6.01 3.50 7.20 2.40 7.00 3.70 8.30 2.40 6.80 2.50 7.10 2.50 7.20 2.50 7.10 2.40 6.80 2.50 7.10 2.50 7.20
WBC, x10^3/uL 3.44 4.00 10.50 3.40 10.80 4.00 13.20 3.80 12.30 3.40 11.90 3.20 11.40 3.40 11.90 3.80 12.30 3.40 11.90 3.20 11.40
N = 3,077. % Missing = percent of missing data. Hispanic = Mexican American or Other Hispanic. ALT = Alanine aminotransferase. ALP = Alkaline phosphatase. BUN = Blood urea nitrogen. CPK = Creatine phosphokinase. GGT = Gamma-glutamyl transferase. LDH = lactate dehydrogenase. MCHC = Mean cell hemoglobin concentration. RBC = Red blood cell count. RCDW = Red cell distribution width. WBC = White blood cell count. SNP = Segmented neutrophils percent. All the laboratory tests in “Standard Biochemistry Profile” and “Complete Blood Count with 5-Part Differential in Whole Blood” data were utilized from the NHANES 2011-2012 Laboratory Data. Lower and upper limits of normal range were defined as 2.5th and 97.5th values in percent, respectively.
Different reference interval by sex by the NHANES manual. If there is no distinction between sex, same reference intervals are given for male and female.
Reference interval is not available in the NHANES manual. The common reference interval is given, excerpt from the following website, http://musom.marshall.edu/usmle/usmlelabvalues.htm.
Note. According to the NHANES manual, reference intervals for most biochemistry laboratory tests were established from Tietz’ textbook and reference intervals for blood chemistry laboratory tests were calculated from the NHANES data set (1999-2004) using 95% reference interval(s) determined non-parametrically, through ranking the observations and determining the lower (2.5th percentile) and the upper (97.5th percentile) reference limits. Reference intervals for blood chemistry laboratory tests are those corresponding to the age group of 19-65.

Table 2: Female

Table: Female Laboratory Test Ranges by Ethnicity
Laboratory Test % Missing White Black Hispanic Asian
Low High Low High Low High Low High
Albumin, g/dL 5.98 3.54 4.91 3.57 4.98 3.55 4.93 3.47 4.84
ALT, U/L 6.11 7.00 55.00 6.00 55.00 6.00 53.00 6.00 54.00
ALP, U/L 6.01 32.00 109.00 32.00 108.00 33.00 111.00 33.00 110.00
Basophils Percent, % 3.61 0.03 0.47 0.02 0.43 0.03 0.45 0.03 0.43
Bicarbonate, mmol/L 6.08 18.00 27.00 18.00 29.00 18.00 28.00 17.00 27.00
BUN, mg/dL 5.98 5.00 20.00 6.00 22.00 5.00 20.00 6.00 21.00
Calcium, mg/dL 6.11 8.80 10.30 8.80 10.40 8.80 10.40 8.70 10.40
Chloride, meq/L 6.01 99.00 110.00 97.00 109.00 98.00 109.00 98.00 108.00
CPK, IU/L 6.08 31.00 143.00 32.00 137.00 30.00 145.00 30.00 142.00
Creatinine, mg/dL 5.98 0.50 1.27 0.67 1.45 0.68 1.25 0.68 1.24
Eosinophils Percent, % 6.11 0.00 6.60 0.00 8.10 0.00 6.70 0.00 6.70
GGT, IU/L 6.01 10.00 47.00 10.00 49.00 10.00 47.00 10.00 46.00
Globulin, g/dL 6.11 2.50 3.40 2.30 4.10 2.40 3.40 2.50 3.50
Glucose, mg/dL 6.01 67.00 110.00 67.00 109.00 67.00 109.00 68.00 108.00
Hematocrit, % 3.44 34.40 44.90 37.50 49.50 36.20 47.90 36.40 49.50
Hemoglobin, g/dL 3.44 12.30 15.60 13.30 17.20 12.80 15.80 12.90 15.80
Iron, µg/dL 5.98 38.00 159.00 39.00 147.00 36.00 146.00 38.00 146.00
LDH, IU/L 6.08 86.00 172.00 87.00 183.00 86.00 188.00 83.00 171.00
Lymphocyte Percent, % 6.11 19.50 45.10 19.60 43.10 18.30 41.70 19.30 39.00
Mean Cell Hemoglobin, pg 3.44 25.60 34.60 27.30 34.40 25.90 34.00 25.90 34.00
MCHC, g/dL 3.44 31.60 36.40 31.90 36.10 31.70 36.50 31.70 36.60
Mean Cell Volume, fL 3.44 78.90 98.70 79.80 98.90 78.90 98.90 78.80 98.60
Mean Platelet Volume, fL 6.08 7.90 12.50 8.10 12.60 7.90 12.40 7.80 12.40
Monocyte Percent, % 6.11 3.10 11.50 3.50 10.80 3.10 10.20 3.00 11.50
Osmolality, mOsm/kg 6.01 268.00 286.00 269.00 285.00 268.00 286.00 268.00 286.00
Phosphorus, mg/dL 6.11 2.40 5.10 2.40 5.30 2.40 5.20 2.40 5.10
Platelet Count, % 3.44 139.00 362.00 134.00 346.00 133.00 340.00 130.00 336.00
Potassium, meq/L 6.11 3.60 5.30 3.80 5.40 3.80 5.40 3.70 5.30
RBC, x10^6/uL 3.44 4.18 5.75 4.05 5.97 4.06 5.97 4.06 5.97
RDW, % 6.08 12.10 15.40 12.30 15.50 12.40 15.40 12.20 15.40
SNP, % 6.01 12.50 14.90 12.80 14.60 12.50 14.90 12.40 14.80
Sodium, meq/L 6.01 135.00 143.00 135.00 144.00 135.00 143.00 135.00 142.00
Total Bilirubin, mg/dL 6.08 0.21 1.18 0.25 1.21 0.21 1.14 0.20 1.13
Total Cholesterol, mg/dL 6.01 121.00 276.00 116.00 287.00 118.00 295.00 118.00 274.00
Total Protein, g/dL 6.08 6.00 8.40 5.70 8.30 5.70 8.20 5.80 8.30
Triglycerides, mg/dL 6.11 30.00 239.00 35.00 253.00 30.00 257.00 30.00 252.00
Uric Acid, mg/dL 6.01 2.50 7.10 2.40 6.80 2.50 7.10 2.50 7.20
WBC, x10^3/uL 3.44 3.40 11.90 3.80 12.30 3.40 11.90 3.20 11.40

Table 3: Male

Table: Male Laboratory Test Ranges by Ethnicity
Laboratory Test % Missing White Black Hispanic Asian
Low High Low High Low High Low High
Albumin, g/dL 5.98 3.51 4.91 3.57 4.98 3.55 4.93 3.47 4.84
ALT, U/L 6.11 5.00 58.00 6.00 55.00 6.00 53.00 6.00 54.00
ALP, U/L 6.01 38.00 114.00 32.00 108.00 33.00 111.00 33.00 110.00
Basophils Percent, % 3.61 0.02 0.42 0.02 0.43 0.03 0.45 0.03 0.43
Bicarbonate, mmol/L 6.08 18.00 29.00 18.00 29.00 18.00 28.00 17.00 27.00
BUN, mg/dL 5.98 6.00 22.00 6.00 22.00 5.00 20.00 6.00 21.00
Calcium, mg/dL 6.11 8.60 10.50 8.80 10.40 8.80 10.40 8.70 10.40
Chloride, meq/L 6.01 97.00 109.00 97.00 109.00 98.00 109.00 98.00 108.00
CPK, IU/L 6.08 38.00 143.00 32.00 137.00 30.00 145.00 30.00 142.00
Creatinine, mg/dL 5.98 0.73 1.45 0.67 1.45 0.68 1.25 0.68 1.24
Eosinophils Percent, % 6.11 0.00 6.80 0.00 8.10 0.00 6.70 0.00 6.70
GGT, IU/L 6.01 11.00 67.00 10.00 49.00 10.00 47.00 10.00 46.00
Globulin, g/dL 6.11 2.30 4.40 2.30 4.10 2.40 3.40 2.50 3.50
Glucose, mg/dL 6.01 68.00 108.00 67.00 109.00 67.00 109.00 68.00 108.00
Hematocrit, % 3.44 38.10 50.00 37.50 49.50 36.20 47.90 36.40 49.50
Hemoglobin, g/dL 3.44 13.70 17.50 13.30 17.20 12.80 15.80 12.90 15.80
Iron, µg/dL 5.98 47.00 192.00 39.00 147.00 36.00 146.00 38.00 146.00
LDH, IU/L 6.08 87.00 206.00 87.00 183.00 86.00 188.00 83.00 171.00
Lymphocyte Percent, % 6.11 20.40 44.70 19.60 43.10 18.30 41.70 19.30 39.00
Mean Cell Hemoglobin, pg 3.44 26.30 34.60 27.30 34.40 25.90 34.00 25.90 34.00
MCHC, g/dL 3.44 31.40 36.30 31.90 36.10 31.70 36.50 31.70 36.60
Mean Cell Volume, fL 3.44 82.90 99.30 79.80 98.90 78.90 98.90 78.80 98.60
Mean Platelet Volume, fL 6.08 8.40 12.80 8.10 12.60 7.90 12.40 7.80 12.40
Monocyte Percent, % 6.11 3.40 11.00 3.50 10.80 3.10 10.20 3.00 11.50
Osmolality, mOsm/kg 6.01 271.00 286.00 269.00 285.00 268.00 286.00 268.00 286.00
Phosphorus, mg/dL 6.11 2.50 5.40 2.40 5.30 2.40 5.20 2.40 5.10
Platelet Count, % 3.44 134.00 349.00 134.00 346.00 133.00 340.00 130.00 336.00
Potassium, meq/L 6.11 3.90 5.50 3.80 5.40 3.80 5.40 3.70 5.30
RBC, x10^6/uL 3.44 4.14 6.16 4.05 5.97 4.06 5.97 4.06 5.97
RDW, % 6.08 12.30 15.50 12.30 15.50 12.40 15.40 12.20 15.40
SNP, % 6.01 13.00 15.50 12.80 14.60 12.50 14.90 12.40 14.80
Sodium, meq/L 6.01 135.00 143.00 135.00 144.00 135.00 143.00 135.00 142.00
Total Bilirubin, mg/dL 6.08 0.29 1.33 0.25 1.21 0.21 1.14 0.20 1.13
Total Cholesterol, mg/dL 6.01 111.00 278.00 116.00 287.00 118.00 295.00 118.00 274.00
Total Protein, g/dL 6.08 5.80 8.20 5.70 8.30 5.70 8.20 5.80 8.30
Triglycerides, mg/dL 6.11 37.00 486.00 35.00 253.00 30.00 257.00 30.00 252.00
Uric Acid, mg/dL 6.01 3.70 8.30 2.40 6.80 2.50 7.10 2.50 7.20
WBC, x10^3/uL 3.44 4.00 13.20 3.80 12.30 3.40 11.90 3.20 11.40