Characteristic Overall, N = 441 No OUTCOME, N = 221 Yes OUTCOME, N = 221 p-value2
mitra_clip_date 2016-10-28 to 2023-06-14 2016-12-02 to 2023-06-14 2016-10-28 to 2023-02-08 0.3
date_of_birth 1935-02-28 to 1968-08-07 1936-03-20 to 1964-11-19 1935-02-28 to 1968-08-07 0.3
age_at_baseline 70 (65, 76) 73 (66, 78) 67 (63, 76) 0.13
gender_0_f 34 (77%) 18 (82%) 16 (73%) 0.5
height_cm 171 (168, 175) 170 (164, 174) 173 (169, 176) 0.13
weight_kg 78 (68, 86) 76 (68, 85) 78 (69, 87) 0.7
bsa_m2.x 1.89 (1.82, 2.00) 1.85 (1.76, 1.98) 1.92 (1.85, 2.01) 0.2
bmi_kg_m2 25.4 (23.7, 29.7) 25.2 (23.3, 29.4) 25.4 (23.7, 29.5) 0.8
betabl_1yes 40 (91%) 19 (86%) 21 (95%) 0.6
renine_antag 0 (0%) 0 (0%) 0 (0%)
acei_arb 21 (48%) 11 (50%) 10 (45%) 0.8
sacubitril_vals 15 (34%) 8 (36%) 7 (32%) 0.8
aldost_antag 22 (50%) 9 (41%) 13 (59%) 0.2
asa 17 (39%) 8 (36%) 9 (41%) 0.8
oac_noac 32 (73%) 16 (73%) 16 (73%) >0.9
statin 33 (75%) 18 (82%) 15 (68%) 0.3
ca_antag 0 (0%) 0 (0%) 0 (0%)
diuretics_others 41 (93%) 20 (91%) 21 (95%) >0.9
hypertension 33 (75%) 16 (73%) 17 (77%) 0.7
diabetes 16 (36%) 3 (14%) 13 (59%) 0.002
hyperlipidemia 38 (86%) 19 (86%) 19 (86%) >0.9
ckd 34 (77%) 18 (82%) 16 (73%) 0.5
anemia 21 (48%) 9 (41%) 12 (55%) 0.4
hb 12.65 (11.95, 14.20) 13.30 (12.13, 14.18) 12.50 (11.85, 14.30) 0.8
cad 34 (77%) 18 (82%) 16 (73%) 0.5
previous_mi 32 (73%) 15 (68%) 17 (77%) 0.5
cabg 20 (45%) 10 (45%) 10 (45%) >0.9
pad 17 (39%) 7 (32%) 10 (45%) 0.4
smoking_history 30 (68%) 13 (59%) 17 (77%) 0.2
smoking_active 8 (18%) 2 (9.1%) 6 (27%) 0.2
af_at_baseline 17 (39%) 9 (41%) 8 (36%) 0.8
paroxysmal_af 19 (43%) 11 (50%) 8 (36%) 0.4
chronic_af 6 (14%) 2 (9.1%) 4 (18%) 0.7
copd 12 (27%) 4 (18%) 8 (36%) 0.2
pacemaker 25 (57%) 12 (55%) 13 (59%) 0.8
crt 17 (39%) 10 (45%) 7 (32%) 0.4
icd 20 (45%) 10 (45%) 10 (45%) >0.9
euro_score_1_logistic 10 (4, 23) 12 (3, 24) 10 (5, 19) 0.7
euro_score_ii 13 (7, 23) 11 (6, 16) 15 (7, 28) 0.2
sts 4.8 (2.5, 8.1) 6.0 (4.4, 7.7) 3.9 (2.2, 8.2) 0.5
sbp_mm_hg 113 (100, 127) 120 (100, 130) 110 (101, 120) 0.3
dbp_mm_hg 70 (60, 80) 70 (60, 75) 70 (60, 80) 0.8
hr_bpm 70 (62, 80) 69 (63, 78) 74 (59, 83) 0.6
heart_rhythm


0.9
    AF 2 (4.5%) 1 (4.5%) 1 (4.5%)
    PM 18 (41%) 10 (45%) 8 (36%)
    SR 24 (55%) 11 (50%) 13 (59%)
chol_mg_dl 144 (123, 170) 156 (134, 172) 132 (121, 170) 0.4
ldl_mg_dl 81 (54, 104) 85 (61, 104) 67 (53, 104) 0.4
hdl_mg_dl 47 (40, 54) 48 (41, 56) 46 (40, 52) 0.7
tg_mg_dl 95 (84, 140) 97 (86, 140) 93 (78, 135) 0.8
creat_mg_dl 1.66 (1.33, 2.11) 1.76 (1.35, 2.12) 1.55 (1.19, 1.86) 0.4
e_gfr_ml_min_1_73m2 43 (30, 54) 41 (32, 51) 45 (29, 59) 0.5
pro_bnp_ng_l 3,845 (1,737, 5,869) 3,808 (2,633, 6,045) 3,882 (1,732, 5,683) >0.9
bnp_pg_ml 711 (529, 1,480) 628 (539, 992) 1,290 (378, 1,540) 0.6
symptoms 44 (100%) 22 (100%) 22 (100%)
first_symptoms_date 42,692 (41,308, 43,046) 42,552 (40,909, 42,738) 42,856 (41,888, 43,150) 0.11
nyha_class_2 12 (27%) 9 (41%) 3 (14%) 0.042
nyha_class_3 0.00 (0.00, 1.00) 0.00 (0.00, 1.00) 0.50 (0.00, 1.00) 0.5
nyha_class_4 13 (30%) 5 (23%) 8 (36%) 0.3
hosp_cv_year_before 34 (89%) 15 (83%) 19 (95%) 0.3
hosp_no 2.00 (1.00, 3.00) 1.00 (1.00, 2.00) 2.00 (2.00, 3.00) 0.089
hosp_cause


0.4
    FA 1 (2.9%) 0 (0%) 1 (5.3%)
    FV sur NSTEMI 1 (2.9%) 1 (6.7%) 0 (0%)
    HF 31 (91%) 13 (87%) 18 (95%)
    TAVI 1 (2.9%) 1 (6.7%) 0 (0%)
x6_mwt 272 (218, 336) 318 (262, 375) 221 (188, 324) 0.036
euro_qol 21 (68%) 9 (64%) 12 (71%) >0.9
euro_qol_score 9.00 (7.00, 12.00) 7.00 (5.00, 10.00) 9.50 (7.75, 12.00) 0.2
vas 60 (50, 80) 70 (60, 80) 53 (48, 70) 0.2
mr_primary 2 (4.5%) 1 (4.5%) 1 (4.5%) >0.9
mr_secondary 44 (100%) 22 (100%) 22 (100%)
mr_mix 2 (4.5%) 1 (4.5%) 1 (4.5%) >0.9
x0_tte_date 2016-05-31 to 2023-03-16 2016-12-01 to 2023-03-16 2016-05-31 to 2022-09-15 0.4
x0_bsa_m2 1.89 (1.82, 2.00) 1.85 (1.76, 1.98) 1.92 (1.85, 2.01) 0.2
x0_hr_bpm 70 (62, 80) 69 (63, 78) 74 (59, 83) 0.6
x0_heart_rhythm


0.9
    AF 2 (4.5%) 1 (4.5%) 1 (4.5%)
    PM 18 (41%) 10 (45%) 8 (36%)
    SR 24 (55%) 11 (50%) 13 (59%)
x0_sbp_mm_hg 113 (100, 127) 120 (100, 130) 110 (101, 120) 0.3
x0_dbp_mm_hg 70 (60, 80) 70 (60, 75) 70 (60, 80) 0.8
x0_iv_sd_mm 10.50 (8.75, 13.00) 11.00 (9.00, 13.00) 9.75 (8.25, 11.88) 0.5
x0_lve_dd_mm 65 (60, 71) 64 (60, 67) 70 (58, 74) 0.2
x0_lve_dd_bsa_mm_m2 35.1 (32.8, 37.3) 35.1 (33.6, 36.4) 35.1 (31.8, 38.7) 0.7
x0_p_wd_mm 9.00 (8.00, 10.00) 8.50 (7.05, 10.00) 9.00 (8.00, 10.00) 0.3
x0_iv_ss_mm 13.00 (11.25, 15.75) 13.00 (11.00, 17.00) 13.00 (12.00, 14.25) >0.9
x0_lvesd_mm 55 (49, 62) 54 (49, 60) 59 (48, 65) 0.4
x0_p_ws_mm 11.2 (9.0, 13.8) 11.0 (9.0, 13.0) 11.7 (10.0, 14.3) 0.3
x0_lvesd_bsa_mm_m2 29.9 (26.5, 34.0) 29.0 (26.6, 33.5) 30.3 (26.9, 34.5) 0.6
cube_formula_lv_mass 298 (240, 335) 294 (233, 317) 314 (248, 379) 0.2
jaki_wzor_0_lv_mass_g 308 (248, 364) 304 (227, 343) 339 (256, 382) 0.3
x0_lv_mass_bsa_g_m2 159 (128, 179) 158 (127, 176) 160 (131, 199) 0.4
x0_rwt 0.28 (0.22, 0.34) 0.28 (0.22, 0.34) 0.28 (0.23, 0.34) 0.9
x0_lvo_tdiam_mm.x 22.75 (21.00, 24.00) 22.75 (21.00, 23.00) 22.50 (21.00, 24.00) >0.9
x0_la_plax_mm 51 (47, 56) 52 (48, 59) 51 (44, 55) 0.3
x0_mv_tenting_area_mm2 364 (245, 446) 343 (241, 436) 387 (258, 477) 0.5
x0_mv_coapt_distans_mm 14.0 (11.5, 17.0) 14.0 (12.0, 16.0) 16.0 (11.5, 17.8) 0.3
x0_vena_contr_mm 7.00 (5.00, 8.00) 7.00 (5.25, 8.00) 6.50 (4.00, 8.00) 0.6
x0_lvedv_4c_ml 185 (140, 255) 172 (151, 221) 217 (129, 265) 0.7
x0_lvesv_4c_ml 123 (95, 159) 124 (97, 144) 120 (89, 178) 0.8
x0_lvedv_2c_ml 211 (149, 257) 190 (153, 248) 220 (147, 270) 0.8
x0_lvesv_2c_ml 140 (91, 183) 141 (99, 165) 139 (86, 188) 0.5
x0_lvedv_bip_ml 192 (147, 246) 187 (165, 232) 216 (132, 252) 0.9
x0_lvedv_bip_bsa_ml_m2 105 (78, 131) 101 (90, 121) 107 (66, 133) 0.7
x0_lvesv_bip_ml 132 (94, 186) 130 (102, 164) 141 (83, 190) 0.7
x0_lvesv_bip_bsa_ml_m2 72 (48, 96) 68 (58, 86) 73 (41, 101) 0.8
x0_lvef_bip_percent 31 (26, 36) 32 (25, 36) 31 (26, 36) >0.9
x0_e_wave_cm_s 108 (91, 130) 108 (98, 123) 106 (77, 135) >0.9
x0_dec_t_ms 150 (126, 179) 142 (128, 181) 166 (117, 179) 0.7
x0_a_wave_cm_s 50 (36, 65) 46 (38, 62) 51 (36, 66) 0.5
x0_e_a 2.67 (1.74, 3.51) 3.10 (2.04, 3.37) 2.37 (1.29, 3.75) 0.5
x0_e_med_cm_s 4.50 (4.00, 5.10) 5.00 (3.50, 5.50) 4.00 (4.00, 5.08) 0.8
x0_e_lat_cm_s 7.1 (5.2, 10.0) 9.0 (6.0, 11.5) 7.0 (4.5, 8.0) 0.2
x0_e_e_aver_cm_s 19 (15, 23) 19 (15, 22) 19 (15, 23) 0.9
x0_lav_4c_ml 123 (94, 149) 123 (99, 147) 123 (86, 152) 0.7
x0_lav_2c_ml 111 (87, 163) 108 (97, 143) 130 (67, 180) 0.8
x0_lav_bip_ml 126 (98, 163) 125 (102, 138) 129 (77, 171) >0.9
x0_lavi_ml_m2 69 (50, 83) 68 (58, 77) 75 (48, 90) >0.9
x0_mr_grade_1 0 (0%) 0 (0%) 0 (0%)
x0_mr_grade_2 1 (2.3%) 0 (0%) 1 (4.5%) >0.9
x0_mr_grade_3 6 (14%) 4 (18%) 2 (9.1%) 0.7
x0_mr_grade_4 39 (89%) 19 (86%) 20 (91%) >0.9
x0_vti_mr_cm 154 (134, 199) 148 (136, 199) 164 (133, 184) >0.9
x0_ero_pisa_mm2 30 (22, 41) 30 (20, 42) 31 (24, 40) >0.9
x0_rvol_pisa_ml 48 (35, 64) 48 (33, 70) 48 (42, 57) 0.8
x0_vti_lvot_cm.x 13.9 (11.4, 17.8) 14.9 (11.8, 18.8) 12.8 (11.3, 15.2) 0.13
x0_vti_mitral_cm 23 (19, 28) 22 (19, 29) 23 (19, 28) >0.9
x0_ma_diam_4c_mm 41.0 (36.3, 43.8) 41.0 (36.0, 42.3) 39.5 (37.0, 44.0) 0.9
x0_ma_diam_2c_mm 40.5 (35.5, 45.0) 40.5 (37.0, 43.5) 40.5 (33.8, 45.3) 0.8
x0_mva_vti_cm2 2.69 (1.78, 3.30) 3.22 (1.82, 3.51) 2.39 (1.62, 3.05) 0.2
x0_mva_plan_cm2 4.85 (3.10, 5.40) 3.40 (2.71, 5.45) 5.40 (5.00, 5.40) 0.5
x0_ar_gr_0 24 (59%) 12 (55%) 12 (63%) 0.6
x0_ar_gr_1 14 (33%) 7 (32%) 7 (33%) >0.9
x0_ar_gr_2 4 (9.3%) 2 (9.1%) 2 (9.5%) >0.9
x0_ar_gr_3 1 (2.3%) 1 (4.5%) 0 (0%) >0.9
x0_ar_gr_4 1 (2.3%) 0 (0%) 1 (4.8%) 0.5
x0_mpg_max_mm_hg 4.02 (3.16, 6.77) 4.00 (3.68, 6.64) 4.03 (2.44, 6.89) 0.4
x0_mpg_mean_mm_hg 1.33 (0.95, 2.07) 1.40 (0.85, 1.94) 1.32 (1.12, 2.08) 0.9
x0_rv_plax_mm 36 (32, 42) 36 (33, 42) 35 (31, 39) 0.8
x0_tapse_mm 15.0 (11.0, 19.3) 15.0 (14.0, 19.0) 14.0 (11.0, 19.5) 0.4
x0_s_rv_cm_s 9.00 (7.00, 10.00) 10.00 (7.00, 10.00) 9.00 (6.00, 10.00) 0.4
x0_raa_cm2 22.0 (17.6, 26.5) 22.0 (16.7, 27.6) 21.2 (17.7, 26.0) 0.6
x0_tr_vmax_m_s 3.09 (2.80, 3.50) 3.14 (3.03, 3.54) 2.90 (2.65, 3.50) 0.10
x0_trpg_mm_hg 38 (32, 48) 40 (36, 50) 34 (28, 48) 0.10
x0_ivc_diam_mm 23.0 (19.0, 26.3) 22.0 (18.5, 27.5) 23.0 (22.0, 26.0) 0.8
x0_ivc_compl 10 (26%) 5 (26%) 5 (26%) >0.9
x0_tr_grade_0 2 (4.9%) 0 (0%) 2 (10%) 0.2
x0_tr_grade_1 15 (37%) 8 (38%) 7 (35%) 0.8
x0_tr_grade_2 13 (32%) 6 (29%) 7 (35%) 0.7
x0_tr_grade_3 5 (12%) 3 (14%) 2 (10%) >0.9
x0_tr_grade_4 6 (14%) 4 (18%) 2 (9.5%) 0.7
x0_gls_percent -7.4 (-11.2, -5.0) -7.1 (-10.1, -5.4) -8.7 (-10.8, -4.6) >0.9
teer_proc_dur_min 115 (92, 175) 115 (100, 146) 118 (89, 180) >0.9
teer_no_clips 2.00 (2.00, 2.00) 2.00 (2.00, 2.00) 2.00 (1.25, 2.00) 0.9
teer_hosp_stay_days 6.00 (4.00, 7.00) 5.50 (4.00, 7.00) 6.00 (4.75, 7.00) 0.3
teer_mace_ae 0 (0%) 0 (0%) 0 (0%)
teer_mace_ae_type 0 (0%) 0 (0%) 0 (0%)
teer_complic_post_op


0.5
    0 8 (44%) 6 (55%) 2 (29%)
    Arythmie ventriculaire, FA 1 (5.6%) 0 (0%) 1 (14%)
    BPN 1 (5.6%) 1 (9.1%) 0 (0%)
    Dobutamine 1 (5.6%) 0 (0%) 1 (14%)
    hypothyroidie, altération des tests hépatiques 1 (5.6%) 1 (9.1%) 0 (0%)
    IRA 2 (11%) 1 (9.1%) 1 (14%)
    Pyélonéphrite 1 (5.6%) 0 (0%) 1 (14%)
    Torsade de pointe 1 (5.6%) 1 (9.1%) 0 (0%)
    TV 1 (5.6%) 1 (9.1%) 0 (0%)
    VAP, flutter 1 (5.6%) 0 (0%) 1 (14%)
teer_dapt_as_aflow 16 (36%) 8 (36%) 8 (36%) >0.9
teer_dapt_clopidogrel 27 (61%) 15 (68%) 12 (55%) 0.4
teer_oac 33 (75%) 16 (73%) 17 (77%) 0.7
x1_tte_date 2016-10-31 to 2023-06-26 2016-12-05 to 2023-06-26 2016-10-31 to 2023-02-09 0.3
x1_bsa_m2 1.89 (1.82, 2.00) 1.85 (1.76, 1.98) 1.92 (1.85, 2.01) 0.2
x1_hr_bpm 68 (63, 75) 66 (60, 74) 70 (65, 75) 0.4
x1_rhythm


0.2
    AF 1 (2.4%) 1 (5.0%) 0 (0%)
    AF/SR 1 (2.4%) 0 (0%) 1 (4.8%)
    AFL 1 (2.4%) 1 (5.0%) 0 (0%)
    PM 15 (37%) 5 (25%) 10 (48%)
    SR 23 (56%) 13 (65%) 10 (48%)
x1_sbp_mm_hg 110 (100, 120) 110 (100, 120) 110 (100, 123) 0.8
x1_dbp_mm_hg 60 (60, 70) 60 (60, 70) 60 (60, 70) 0.8
x1_iv_sd_mm 11.00 (10.00, 13.00) 11.00 (10.00, 13.00) 11.00 (10.00, 12.00) >0.9
x1_lve_dd_mm 64 (57, 70) 63 (57, 67) 67 (58, 74) 0.3
x1_lve_dd_bsa_mm_m2 34.7 (32.4, 37.2) 34.4 (32.4, 35.8) 34.8 (32.5, 37.8) 0.5
x1_p_wd_mm 9.00 (8.00, 10.00) 9.00 (8.00, 10.00) 9.00 (8.00, 10.00) 0.4
x1_iv_ss_mm 13.50 (12.00, 15.00) 14.00 (11.50, 15.00) 13.00 (12.00, 15.00) 0.7
x1_lvesd_mm 57 (50, 63) 55 (46, 60) 57 (51, 65) 0.4
x1_p_ws_mm 11.5 (9.3, 14.0) 12.0 (9.0, 13.0) 11.0 (10.5, 14.0) 0.5
x1_lvesd_bsa_mm_m2 30.0 (27.5, 34.2) 29.8 (26.9, 32.5) 30.2 (28.0, 35.2) 0.4
x1_lvedv_bip_ml 215 (150, 255) 206 (163, 255) 215 (138, 252) >0.9
x1_lvedv_bip_bsa_ml_m2 113 (82, 133) 108 (90, 134) 115 (79, 131) >0.9
x1_lvesv_bip_ml 158 (94, 194) 149 (110, 193) 158 (86, 193) >0.9
x1_lvesv_bip_bsa_ml_m2 80 (52, 97) 80 (61, 97) 80 (49, 97) >0.9
x1_lv_mass_g 360 (282, 395) 319 (267, 380) 386 (304, 405) 0.2
x1_lv_mass_bsa_g_m2 184 (147, 208) 183 (146, 197) 189 (160, 219) 0.2
x1_rwt 0.29 (0.23, 0.33) 0.29 (0.24, 0.33) 0.30 (0.23, 0.34) 0.9
x1_lvo_tdiam_mm.x 23.00 (21.00, 24.00) 22.50 (21.00, 23.88) 23.00 (21.00, 24.00) 0.8
x1_la_plax_mm 53 (46, 55) 53 (49, 57) 51 (42, 54) 0.3
x1_vena_contr_mm 6.0000 (6.0000, 6.0000) 6.0000 (6.0000, 6.0000) NA (NA, NA)
x1_lvedv_4c_ml 206 (136, 238) 197 (137, 259) 207 (140, 232) >0.9
x1_lvesv_4c_ml 147 (89, 193) 128 (91, 195) 150 (90, 178) >0.9
x1_lvedv_2c_ml 220 (143, 260) 220 (175, 251) 215 (137, 263) >0.9
x1_lvesv_2c_ml 160 (98, 193) 162 (109, 189) 158 (84, 196) >0.9
x1_lvef_bip_percent 28 (23, 38) 28 (24, 36) 30 (23, 38) 0.9
x1_e_wave_cm_s 124 (109, 132) 117 (102, 129) 130 (121, 140) 0.2
x1_dec_t_ms 258 (174, 395) 228 (181, 378) 356 (171, 405) >0.9
x1_a_wave_cm_s 75 (62, 119) 115 (56, 138) 70 (64, 85) 0.4
x1_e_a 1.98 (1.18, 2.28) 1.57 (1.04, 2.19) 2.08 (1.78, 2.28) 0.7
x1_e_med_cm_s 5.00 (3.00, 5.50) 5.00 (3.00, 7.00) 4.50 (3.75, 5.13) 0.6
x1_e_lat_cm_s 6.00 (5.00, 7.00) 6.00 (5.00, 9.00) 6.00 (5.13, 6.25) 0.8
x1_e_e_aver_cm_s 20.0 (19.0, 21.0) 19.5 (17.0, 21.3) 21.0 (21.0, 21.0) 0.8
x1_lav_4c_ml 114 (91, 148) 108 (96, 131) 125 (80, 158) 0.8
x1_lav_2c_ml 123 (101, 157) 122 (107, 139) 129 (79, 165) 0.8
x1_lav_bip_ml 118 (99, 152) 116 (106, 140) 125 (93, 162) >0.9
x1_lavi_ml_m2 63 (54, 81) 64 (58, 74) 61 (53, 85) >0.9
x1_mr_gr_0 2 (4.9%) 2 (10%) 0 (0%) 0.2
x1_mr_gr_1 11 (27%) 7 (35%) 4 (19%) 0.2
x1_mr_gr_2 21 (51%) 8 (40%) 13 (62%) 0.2
x1_mr_gr_3 7 (17%) 3 (15%) 4 (19%) >0.9
x1_mr_gr_4 0 (0%) 0 (0%) 0 (0%)
x1_vti_mr_cm 162 (144, 185) 180 (123, 192) 162 (147, 162) >0.9
x1_ero_pisa_mm2 14 (12, 14) 14 (12, 20) 13 (11, 14) 0.6
x1_rvol_pisa_ml 23.0 (20.4, 24.7) 24.4 (23.0, 24.7) 20.3 (18.4, 22.3) 0.2
x1_vti_lvot_cm.x 15.9 (12.0, 19.2) 18.8 (16.5, 20.8) 14.0 (11.8, 15.8) 0.001
x1_vti_mitral_cm 38 (35, 44) 41 (35, 45) 38 (29, 42) 0.4
x1_ma_diam_4c_mm 39.5 (35.0, 42.0) 39.0 (32.5, 41.5) 40.0 (35.5, 44.0) 0.3
x1_ma_diam_2c_mm 42 (37, 48) 41 (36, 43) 44 (40, 50) 0.059
x1_mva_vti_cm2 1.65 (1.42, 2.14) 1.58 (1.40, 1.98) 1.71 (1.47, 2.14) 0.8
x1_mva_plan 1.6000 (1.6000, 1.6000) 1.6000 (1.6000, 1.6000) 1.6000 (1.6000, 1.6000)
x1_ar_gr_0 20 (49%) 9 (45%) 11 (52%) 0.6
x1_ar_gr_1 14 (34%) 7 (35%) 7 (33%) >0.9
x1_ar_gr_2 4 (9.8%) 2 (10%) 2 (9.5%) >0.9
x1_ar_gr_3 1 (2.4%) 1 (5.0%) 0 (0%) 0.5
x1_ar_gr_4 0 (0%) 0 (0%) 0 (0%)
x1_mpg_max_mm_hg 9.55 (7.27, 11.73) 10.13 (7.83, 12.33) 9.20 (7.20, 11.12) 0.4
x1_mpg_mean_mm_hg 3.18 (2.60, 4.33) 3.05 (2.76, 4.64) 3.63 (2.52, 3.94) 0.8
x1_rv_plax_mm 38 (33, 40) 38 (36, 44) 36 (31, 40) 0.2
x1_tapse_mm 17.0 (14.5, 19.0) 18.0 (15.8, 19.3) 16.0 (13.0, 17.0) 0.055
x1_s_rv_cm_s 10.00 (9.00, 11.00) 11.00 (9.00, 11.25) 9.50 (7.25, 10.00) 0.051
x1_raa_cm2 23 (16, 26) 25 (20, 27) 19 (15, 25) 0.035
x1_tr_vmax_m_s 2.96 (2.64, 3.28) 3.07 (2.83, 3.50) 2.88 (2.60, 3.04) 0.3
x1_trpg_mm_hg 35 (26, 42) 36 (27, 46) 32 (26, 37) 0.2
x1_ivc_diam_mm 20.5 (15.8, 24.8) 20.5 (18.3, 24.3) 21.0 (15.0, 24.3) >0.9
x1_ivc_compl 19 (56%) 10 (56%) 9 (56%) >0.9
x1_tr_grade_0 0 (0%) 0 (0%) 0 (0%)
x1_tr_grade_1 14 (35%) 7 (35%) 7 (35%) >0.9
x1_tr_grade_2 18 (45%) 7 (35%) 11 (55%) 0.2
x1_tr_grade_3 5 (13%) 4 (20%) 1 (5.0%) 0.3
x1_tr_grade_4 3 (7.5%) 2 (10%) 1 (5.0%) >0.9
x1_gls_percent -7.2 (-10.1, -5.6) -7.2 (-8.8, -5.7) -7.3 (-11.3, -5.3) 0.7
tte_f_up_date 2017-03-21 to 2024-01-31 2017-04-19 to 2024-01-31 2017-03-21 to 2021-12-11 0.4
f_up_bsa_m2 1.89 (1.82, 2.00) 1.85 (1.76, 1.98) 1.93 (1.87, 2.01) 0.14
f_up_hr_bpm 66 (60, 73) 60 (59, 71) 70 (65, 78) 0.047
f_up_rhythm


0.5
    AF 3 (9.1%) 1 (5.6%) 2 (13%)
    AFL 1 (3.0%) 1 (5.6%) 0 (0%)
    PM 8 (24%) 3 (17%) 5 (33%)
    SR 21 (64%) 13 (72%) 8 (53%)
f_up_sbp_mm_hg 110 (100, 140) 120 (103, 148) 100 (98, 128) 0.14
f_up_dbp_mm_hg 65 (60, 70) 70 (60, 80) 60 (60, 68) 0.088
f_up_iv_sd_mm 10.00 (9.00, 12.25) 10.00 (8.50, 12.50) 10.00 (9.00, 12.00) >0.9
f_up_lve_dd_mm 63 (57, 69) 62 (56, 67) 64 (59, 70) 0.2
f_up_lve_dd_bsa_mm_m2 33.4 (31.6, 36.6) 33.3 (31.6, 36.2) 33.5 (31.8, 36.1) 0.8
f_up_p_wd_mm 9.00 (7.00, 10.00) 9.00 (7.00, 9.50) 10.00 (8.00, 10.00) 0.4
f_up_iv_ss_mm 14.0 (10.0, 16.0) 14.0 (11.0, 15.8) 13.0 (10.0, 16.0) >0.9
f_up_lvesd_mm 57 (48, 62) 56 (45, 62) 57 (48, 62) 0.5
f_up_p_ws_mm 11.00 (9.00, 13.00) 10.00 (9.10, 12.00) 12.00 (9.00, 13.00) 0.4
f_up_lvesd_bsa_mm_m2 29.5 (24.9, 32.3) 29.7 (24.8, 32.1) 29.4 (26.8, 33.0) 0.8
f_up_lvedv_bip_ml 182 (139, 230) 169 (150, 215) 187 (127, 249) 0.7
f_up_lvedv_bip_bsa_ml_m2 92 (79, 123) 92 (85, 115) 96 (70, 138) 0.7
f_up_lvesv_bip_ml 123 (86, 164) 113 (99, 140) 133 (78, 200) 0.3
f_up_lvesv_bip_bsa_ml_m2 63 (49, 90) 61 (54, 75) 69 (42, 102) 0.4
f_up_lv_mass_g 286 (215, 334) 264 (213, 343) 286 (217, 327) >0.9
f_up_lv_mass_bsa_g_m2 120 (97, 173) 115 (87, 177) 134 (113, 161) >0.9
f_up_rwt 0.33 (0.28, 0.44) 0.32 (0.28, 0.62) 0.33 (0.28, 0.41) 0.8
f_up_lvo_tdiam_mm.x 23.00 (21.00, 24.00) 22.25 (21.00, 24.93) 23.00 (21.00, 24.00) >0.9
f_up_la_plax_mm 52 (46, 59) 53 (46, 59) 49 (42, 61) >0.9
f_up_lvedv_4c_ml 188 (124, 241) 175 (123, 222) 200 (125, 257) 0.4
f_up_lvesv_4c_ml 127 (76, 168) 120 (81, 141) 150 (75, 197) 0.2
f_up_lvedv_2c_ml 173 (138, 218) 171 (143, 209) 173 (131, 249) 0.9
f_up_lvesv_2c_ml 123 (77, 156) 118 (91, 134) 129 (70, 192) 0.6
f_up_lvef_bip_percent 33 (26, 38) 34 (31, 39) 28 (23, 32) 0.030
f_up_e_wave_cm_s 120 (105, 156) 110 (105, 122) 157 (101, 198) 0.4
f_up_dec_t_ms 218 (183, 274) 213 (195, 244) 227 (182, 276) 0.9
f_up_a_wave_cm_s 66 (45, 135) 100 (46, 152) 64 (54, 74) 0.8
f_up_e_a 1.13 (0.71, 2.31) 1.63 (0.59, 2.60) 1.13 (0.97, 1.30) >0.9
f_up_e_med_cm_s 3.00 (3.00, 5.50) 3.00 (3.00, 3.00) 5.00 (3.25, 6.75) 0.10
f_up_e_lat_cm_s 5.00 (4.00, 5.50) 4.00 (4.00, 5.00) 5.00 (4.25, 5.75) 0.9
f_up_e_e_aver_cm_s 23.0 (15.9, 31.0) 23.0 (15.9, 31.0) NA (NA, NA)
f_up_lav_4c_ml 114 (92, 145) 121 (112, 152) 102 (92, 115) 0.12
f_up_lav_2c_ml 119 (94, 142) 115 (93, 135) 125 (108, 139) 0.5
f_up_lav_bip_ml 116 (101, 138) 124 (106, 148) 110 (96, 128) 0.2
f_up_lavi_ml_m2 62 (52, 75) 70 (58, 77) 52 (48, 62) 0.028
f_up_mr_gr_1 7 (21%) 4 (21%) 3 (20%) >0.9
f_up_mr_gr_2 10 (29%) 8 (42%) 2 (13%) 0.13
f_up_mr_gr_3 14 (41%) 7 (37%) 7 (47%) 0.6
f_up_mr_gr_4 3 (8.8%) 0 (0%) 3 (20%) 0.076
f_up_vti_mr_cm 159 (141, 181) 152 (130, 171) 163 (148, 183) 0.7
f_up_ero_pisa_mm2 12.0 (10.0, 15.7) 11.0 (10.0, 14.0) 14.0 (9.5, 15.7) >0.9
f_up_rvol_pisa_ml 20 (15, 25) 22 (18, 27) 20 (12, 23) 0.5
f_up_vti_lvot_cm.x 16.2 (13.1, 19.6) 19.4 (16.7, 21.1) 13.4 (11.4, 14.6) <0.001
f_up_vti_mitral_cm 40 (36, 50) 40 (36, 50) 39 (36, 44) 0.6
f_up_ma_diam_4c_mm 41.0 (37.5, 43.5) 41.0 (38.0, 43.0) 41.0 (37.3, 43.8) >0.9
f_up_ma_diam_2c_mm 43.0 (40.0, 44.5) 41.0 (38.0, 44.0) 44.0 (40.3, 44.8) 0.3
f_up_mva_vti_cm2 1.54 (1.30, 1.80) 1.60 (1.41, 1.80) 1.54 (1.20, 1.73) 0.4
f_up_mva_plan_cm2 1.90 (1.55, 2.15) 1.55 (1.38, 1.73) 2.40 (2.40, 2.40) 0.7
f_up_ar_gr_0 14 (48%) 7 (47%) 7 (50%) 0.9
f_up_ar_gr_1 6 (21%) 3 (20%) 3 (21%) >0.9
f_up_ar_gr_2 0.00 (0.00, 1.00) 0.00 (0.00, 0.50) 0.00 (0.00, 0.75) 0.8
f_up_ar_gr_3 1 (3.4%) 1 (6.7%) 0 (0%) >0.9
f_up_ar_gr_4 0 (0%) 0 (0%) 0 (0%)
f_up_mpg_max_mm_hg 11.0 (8.7, 13.7) 10.5 (8.7, 13.2) 11.2 (9.2, 14.4) 0.8
f_up_mpg_mean_mm_hg 3.95 (3.00, 4.84) 3.95 (3.13, 4.71) 3.95 (2.90, 4.48) 0.8
f_up_rv_plax_mm 37.0 (32.0, 42.0) 37.0 (31.5, 40.0) 35.0 (33.0, 42.0) 0.8
f_up_tapse_mm 16.0 (13.3, 18.8) 17.3 (14.0, 20.3) 15.0 (12.3, 16.8) 0.10
f_up_s_rv_cm_s 9.00 (7.50, 11.00) 9.00 (8.00, 11.00) 9.00 (6.50, 10.75) 0.8
f_up_raa_cm2 22.5 (17.3, 24.7) 22.6 (17.3, 24.9) 20.3 (18.3, 24.1) 0.9
f_up_tr_vmax_m_s 2.97 (2.72, 3.31) 2.96 (2.69, 3.24) 2.98 (2.76, 3.56) 0.7
f_up_trpg_mm_hg 35 (29, 46) 35 (29, 42) 35 (28, 50) >0.9
f_up_ivc_diam_mm 18.5 (14.3, 22.0) 17.0 (13.0, 24.0) 20.0 (15.0, 22.0) 0.8
f_up_ivc_compl 14 (54%) 8 (62%) 6 (46%) 0.4
f_up_tr_gr_1 7 (23%) 2 (12%) 5 (38%) 0.2
f_up_tr_gr_2 17 (57%) 10 (59%) 7 (54%) 0.8
f_up_tr_gr_3 5 (17%) 4 (24%) 1 (7.7%) 0.4
f_up_tr_gr_4 1 (3.3%) 1 (5.9%) 0 (0%) >0.9
f_up_gls_percent -8.9 (-11.4, -5.9) -8.0 (-10.3, -6.4) -9.7 (-11.4, -5.7) 0.9
f_up_nyha_1 1 (3.6%) 0 (0%) 1 (7.1%) >0.9
f_up_nyha_2 20 (71%) 13 (93%) 7 (50%) 0.033
f_up_nyha_3 5 (19%) 1 (7.1%) 4 (31%) 0.2
f_up_nyha_4 2 (7.1%) 0 (0%) 2 (14%) 0.5
f_up_euro_qol 13 (59%) 7 (58%) 6 (60%) >0.9
f_up_euro_qol_score 9.00 (7.00, 13.00) 10.00 (7.00, 11.50) 9.00 (7.50, 12.00) >0.9
f_up_vas_1_100_percent 70 (61, 72) 72 (68, 76) 68 (61, 70) 0.2
f_up_6mwt_m 322 (210, 374) 374 (342, 390) 210 (135, 210) 0.004
f_up_bnp_pg_ml 364 (178, 508) 364 (190, 616) 282 (224, 341) 0.9
cv_death 8 (18%) 0 (0%) 8 (36%) 0.004
all_cause_death 12 (27%) 0 (0%) 12 (55%) <0.001
primary_comp_endpoint 22 (50%) 0 (0%) 22 (100%) <0.001
follow_up_2_year 44 (100%) 22 (100%) 22 (100%)
f_up_first_hospit_date 2017-11-29 to 2022-10-27 2018-01-26 to 2018-08-21 2017-11-29 to 2022-10-27 0.4
hosp_2_yrs 20 (49%) 2 (9.1%) 18 (95%) <0.001
death_date 2017-12-22 to 2023-08-10 Inf to -Inf 2017-12-22 to 2023-08-10
last_living_contact 2019-01-31 to 2024-04-24 2019-03-05 to 2024-04-22 2019-01-31 to 2024-04-24 0.4
reinterv_for_mv_dysfunction 0 (0%) 0 (0%) 0 (0%)
rehosp_for_heart_failure 15 (34%) 0 (0%) 15 (68%) <0.001
cardiac_transplant 1 (2.3%) 0 (0%) 1 (4.5%) >0.9
device_failure 1 (2.3%) 0 (0%) 1 (4.5%) >0.9
pericardial_effusion 0 (0%) 0 (0%) 0 (0%)
myocardial_infarction 0 (0%) 0 (0%) 0 (0%)
stroke 1 (2.3%) 1 (4.5%) 0 (0%) >0.9
severe_atrial_septum_shunt 1 (2.3%) 0 (0%) 1 (4.5%) >0.9
endocarditis 0 (0%) 0 (0%) 0 (0%)
x334


>0.9
    2 x renal transplant 1 (25%) 1 (50%) 0 (0%)
    CIA + Amplatz 1 (25%) 0 (0%) 1 (50%)
    LVAD 1 (25%) 0 (0%) 1 (50%)
    Triclip 13/11/2023 1 (25%) 1 (50%) 0 (0%)
x335



    CARD TRANSPL PLANNED 1 (100%) 0 (NA%) 1 (100%)
x336



    urosepsis 1 (100%) 0 (NA%) 1 (100%)
outcome_cvdeath


0.004
    0 36 (82%) 22 (100%) 14 (64%)
    1 8 (18%) 0 (0%) 8 (36%)
outcome_date 2017-12-16 to 2024-04-22 2018-01-26 to 2024-04-22 2017-12-16 to 2023-08-10 0.018
x0_lvo_tdiam_mm.y 2.28 (2.10, 2.40) 2.28 (2.10, 2.30) 2.25 (2.10, 2.40) >0.9
x1_lvo_tdiam_mm.y 2.30 (2.10, 2.40) 2.25 (2.10, 2.39) 2.30 (2.10, 2.40) 0.8
f_up_lvo_tdiam_mm.y 2.30 (2.10, 2.40) 2.23 (2.10, 2.49) 2.30 (2.10, 2.40) >0.9
x0_vti_lvot_cm.y 13.9 (11.4, 17.8) 14.9 (11.8, 18.8) 12.8 (11.3, 15.2) 0.13
x1_vti_lvot_cm.y 15.9 (12.0, 19.2) 18.8 (16.5, 20.8) 14.0 (11.8, 15.8) 0.001
f_up_vti_lvot_cm.y 16.2 (13.1, 19.6) 19.4 (16.7, 21.1) 13.4 (11.4, 14.6) <0.001
bsa_m2.y 1.89 (1.82, 2.00) 1.85 (1.76, 1.98) 1.92 (1.85, 2.01) 0.2
sv_0_i 30 (24, 36) 31 (25, 36) 29 (22, 34) 0.2
sv_1_i 34 (29, 39) 38 (33, 43) 32 (27, 34) 0.005
sv_2_i 34 (30, 40) 40 (34, 48) 32 (22, 33) 0.001
change_baseline_to_first 4 (0, 9) 7 (3, 11) 1 (-2, 6) 0.008
change_baseline_to_second 3 (-1, 13) 6 (2, 18) 1 (-1, 5) 0.093
change_first_to_second 1 (-3, 4) 1 (-2, 5) -1 (-4, 3) 0.4
time_to_event_days 456 (239, 729) 623 (348, 756) 411 (183, 550) 0.030
1 Range; Median (IQR); n (%)
2 Wilcoxon rank sum test; Wilcoxon rank sum exact test; Pearson’s Chi-squared test; Fisher’s exact test