DMP Publication 2024
Dosing and LATIN
1 Quarto
Quarto enables you to weave together content and executable code into a finished document. To learn more about Quarto see https://quarto.org.
2 Running Code
Code
cat('$$
\\small{
CHG = \\beta_0 + \\beta_1 \\times TRT01PN + \\beta_2 \\times AVISITN + \\beta_3 \\times (TRT01PN \\times AVISITN) + \\beta_4 \\times STRATAGN + \\beta_5 \\times STRATGLN + \\beta_6 \\times BASE + \\epsilon
}
$$')\small{ CHG = \beta_0 + \beta_1 \times TRT01PN + \beta_2 \times AVISITN + \beta_3 \times (TRT01PN \times AVISITN) + \beta_4 \times STRATAGN + \beta_5 \times STRATGLN + \beta_6 \times BASE + \epsilon }
Code
cat('$$
\\begin{align*}
\\text{CHG Contrast} = & -1 \\times \\beta_{\\text{TRT01PN=DTX401}} + 1 \\times \\beta_{\\text{TRT01PN=Placebo}} +
0 \\times \\beta_{\\text{TRT01PN=DTX401, AVISITN=Week 36 }} - 1 \\times \\beta_{\\text{TRT01PN=DTX401, AVISITN=Week 48}} + \\\\&
+0 \\times \\beta_{\\text{TRT01PN=Placebo, AVISITN=Week 36 }} + 1 \\times \\beta_{\\text{TRT01PN=Placebo, AVISITN=Week 48}}
\\end{align*}
$$')\begin{align*} \text{CHG Contrast} = & -1 \times \beta_{\text{TRT01PN=DTX401}} + 1 \times \beta_{\text{TRT01PN=Placebo}} + 0 \times \beta_{\text{TRT01PN=DTX401, AVISITN=Week 36 }} - 1 \times \beta_{\text{TRT01PN=DTX401, AVISITN=Week 48}} + \\& +0 \times \beta_{\text{TRT01PN=Placebo, AVISITN=Week 36 }} + 1 \times \beta_{\text{TRT01PN=Placebo, AVISITN=Week 48}} \end{align*}
Code
cat('$$
\\begin{align*}
Improvement = & \\beta_0 + \\beta_1 \\times \\text{TRTGRPCD} + \\beta_2 \\times \\text{SEX} + \\beta_3 \\times \\text{AGE} + \\beta_4 \\times \\text{age.diag} + \\beta_5 \\times \\text{AAGEPHOS} + \\beta_6 \\times \\text{AAGEVITD} + \\beta_7 \\times \\text{age.first.burmb} + \\beta_8 \\times \\text{HEIGHT} \\\\&
+ \\beta_9 \\times \\text{WEIGHT} + \\beta_{10} \\times \\text{HTZ\\_MONTH\\_0\\_DMDlnk} + \\beta_{11} \\times \\text{HTZ\\_diff} + \\beta_{12} \\times \\text{BMI\\_MONTH\\_0} + \\beta_{13} \\times \\text{BMI\\_diff} + \\beta_{14} \\times \\text{RSS\\_glb\\_bs\\_cat} +\\\\& \\beta_{15} \\times \\text{RSS\\_kne\\_bs\\_cat}
+ \\beta_{16} \\times \\text{phos\\_AVALZ\\_MONTH\\_0\\_DMDlnk} + \\beta_{17} \\times \\text{phosZ\\_diff} + \\beta_{18} \\times \\text{ALPS\\_MONTH\\_0\\_DMDlnk} \\\\& + \\beta_{19} \\times \\text{ALPS\\_diff} + \\beta_{20} \\times \\text{PTHI\\_MONTH\\_0\\_DMDlnk} + \\beta_{21} \\times \\text{VD1\\_25\\_MONTH\\_0}
+ \\beta_{22} \\times \\text{AverageDose\\_DMP} +\\\\& \\beta_{23} \\times \\text{TRTDURW.month} + \\beta_{24} \\times \\text{PHEXBL\\_BL\\_dlnk} + \\epsilon
\\end{align*}
$$')\begin{align*} Improvement = & \beta_0 + \beta_1 \times \text{TRTGRPCD} + \beta_2 \times \text{SEX} + \beta_3 \times \text{AGE} + \beta_4 \times \text{age.diag} + \beta_5 \times \text{AAGEPHOS} + \beta_6 \times \text{AAGEVITD} + \beta_7 \times \text{age.first.burmb} + \beta_8 \times \text{HEIGHT} \\& + \beta_9 \times \text{WEIGHT} + \beta_{10} \times \text{HTZ\_MONTH\_0\_DMDlnk} + \beta_{11} \times \text{HTZ\_diff} + \beta_{12} \times \text{BMI\_MONTH\_0} + \beta_{13} \times \text{BMI\_diff} + \beta_{14} \times \text{RSS\_glb\_bs\_cat} +\\& \beta_{15} \times \text{RSS\_kne\_bs\_cat} + \beta_{16} \times \text{phos\_AVALZ\_MONTH\_0\_DMDlnk} + \beta_{17} \times \text{phosZ\_diff} + \beta_{18} \times \text{ALPS\_MONTH\_0\_DMDlnk} \\& + \beta_{19} \times \text{ALPS\_diff} + \beta_{20} \times \text{PTHI\_MONTH\_0\_DMDlnk} + \beta_{21} \times \text{VD1\_25\_MONTH\_0} + \beta_{22} \times \text{AverageDose\_DMP} +\\& \beta_{23} \times \text{TRTDURW.month} + \beta_{24} \times \text{PHEXBL\_BL\_dlnk} + \epsilon \end{align*}
Code
cat('$$
\\begin{align*}
\\text{Normalized difference} = & \\beta_0 + \\beta_1 \\times \\text{TRTGRPCD} + \\beta_2 \\times \\text{age.first.burmb} + \\beta_{3} \\times \\text{HTZ\\_MONTH\\_0\\_DMDlnk} + \\beta_{4} \\times \\text{HTZ\\_diff} + \\beta_{5} \\times \\text{PHEXBL\\_BL\\_dlnk} + \\epsilon
\\end{align*}
$$')\begin{align*} \text{Normalized difference} = & \beta_0 + \beta_1 \times \text{TRTGRPCD} + \beta_2 \times \text{age.first.burmb} + \beta_{3} \times \text{HTZ\_MONTH\_0\_DMDlnk} + \beta_{4} \times \text{HTZ\_diff} + \beta_{5} \times \text{PHEXBL\_BL\_dlnk} + \epsilon \end{align*}
Citation
@online{eric2024,
author = {Eric},
title = {DMP {Publication} 2024},
date = {2024-05-22},
langid = {en}
}