The goal of this analysis is to combine functional genomic and descriptive genomic data sets for each of the non-driver SUM breast cancer cell lines in order to determine a functional oncogene signature for each cell line.

First let’s set the working directory to the location that contains all of the genomic data sets needed to generate the functional oncogene signatures

setwd("C:/Users/stg43/R_Programming/Oncogene Signatures for Non-Driver Lines")

Next we’ll source the Onc_Sig_Generator.R function that I created

source("C:/Users/stg43/R_Programming/R_functions/Onc_Sig_Generator.R")

Next we’ll run the Onc_Sig_Generator function using “SUM185” as the argument

Onc_Sig_Generator("SUM185")

##  [1] "FGFR3"   "CTBP1"   "IDUA"    "ANKRD17" "GPT2"    "ISYNA1"  "NDUFA13"
##  [8] "HSPBP1"  "ACSS1"   "NKX2-2"  "POFUT1"  "BCL2L1"  "ID1"     "COX4I2" 
## [15] "SSTR4"

## [1] "FGFR3"  "CTBP1"  "IDUA"   "GPT2"   "ISYNA1" "ACSS1"  "NKX2-2" "BCL2L1"
## [9] "ID1"

## [1] "FGFR3"  "BCL2L1" "CTBP1"  "ID1"    "ACSS1"  "IDUA"   "GPT2"   "ISYNA1"
## Warning: Removed 4 rows containing missing values (geom_point).

## Warning: Removed 4 rows containing missing values (geom_point).

## [1] "PIK3CA"