Report 2: Confirming the flag in the system to identify participants who have re-signed an ICF is in place and working.

Description: The following sections detail how re-consent activities are tracked in the ICF database. ICF verification activities were completed on these dates for each cohort

On February 13, 2024, confirmed the procedures for reconsenting activities. Following this, based on the completion dates of the ICF verification, Eldo recommended using “February 15, 2024” to flag all reconsented ICFs. Isak confirmed this approach as preferable to modifying the database structure. This decision was reached via an email exchange involving , , and in a thread titled “Plan for Missing ICFs”.

Safety Cohort

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## Warning in geom_label(aes(x = as.Date("2024-02-15"), y = max(daily_counts$count, : All aesthetics have length 1, but the data has 61 rows.
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## Warning: Use of `filtered_daily_counts$count` is discouraged.
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## Warning in geom_label(aes(x = as.Date("2024-02-15"), y = max(filtered_daily_counts$count, : All aesthetics have length 1, but the data has 18 rows.
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## Warning in geom_label(aes(x = as.Date("2024-02-15"), y = max(filtered_daily_counts$count, : All aesthetics have length 1, but the data has 10 rows.
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Safety: Getting the list of participants who have re-signed ICFs based on the above flag in Safety cohort

Efficacy Cohort

## Warning: Use of `daily_counts$count` is discouraged.
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## Warning in geom_label(aes(x = as.Date("2024-02-15"), y = max(daily_counts$count, : All aesthetics have length 1, but the data has 27 rows.
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## Warning: Use of `filtered_daily_counts$count` is discouraged.
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## Warning in geom_label(aes(x = as.Date("2024-02-15"), y = max(filtered_daily_counts$count, : All aesthetics have length 1, but the data has 13 rows.
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## Warning in geom_label(aes(x = as.Date("2024-02-15"), y = max(filtered_daily_counts$count, : All aesthetics have length 1, but the data has 5 rows.
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Efficacy: Getting the list of participants who have re-signed ICFs based on the above flag in efficacy cohort

PK cohort:

## Warning: Use of `daily_counts$count` is discouraged.
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## Warning in geom_label(aes(x = as.Date("2024-02-15"), y = max(daily_counts$count, : All aesthetics have length 1, but the data has 3 rows.
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PK: Getting the list of participants who have re-signed ICFs based on the above flag in PK cohort