| age, Mean (SD) |
67 (11) |
73 (11) |
69 (10) |
69 (10) |
|
34/34 |
|
| sexe, n (%) |
|
|
|
|
0.30 |
34/34 |
|
| F |
6 (38) |
5 (71) |
6 (55) |
17 (50) |
|
|
|
| H |
10 (63) |
2 (29) |
5 (45) |
17 (50) |
|
|
|
| NGSmo/sg, n (%) |
16 (100) |
7 (100) |
6 (55) |
29 (85) |
0.003 |
34/34 |
|
| NGSpbr, n (%) |
|
|
|
|
<0.001 |
34/34 |
|
| 0 |
15 (94) |
0 (0) |
0 (0) |
15 (44) |
|
|
|
| 1 |
0 (0) |
7 (100) |
11 (100) |
18 (53) |
|
|
|
| en cours |
1 (6.3) |
0 (0) |
0 (0) |
1 (2.9) |
|
|
|
| NGSpbr_variant, n (%) |
|
|
|
|
<0.001 |
18/34 |
|
| non |
0 (NA) |
0 (0) |
11 (100) |
11 (61) |
|
|
|
| oui |
0 (NA) |
7 (100) |
0 (0) |
7 (39) |
|
|
|
| Manquants |
16 |
0 |
0 |
16 |
|
|
|
| hemopath_type, n (%) |
|
|
|
|
>0.99 |
8/34 |
|
| LAM |
0 (0) |
1 (17) |
0 (0) |
1 (13) |
|
|
|
| LMMC |
0 (0) |
1 (17) |
0 (0) |
1 (13) |
|
|
|
| LMMC-2 |
1 (100) |
0 (0) |
0 (0) |
1 (13) |
|
|
|
| MM à CLL kappa |
0 (0) |
1 (17) |
0 (0) |
1 (13) |
|
|
|
| MM IgG kappa |
0 (0) |
0 (0) |
1 (100) |
1 (13) |
|
|
|
| MM IgM lambda |
0 (0) |
1 (17) |
0 (0) |
1 (13) |
|
|
|
| SMD |
0 (0) |
1 (17) |
0 (0) |
1 (13) |
|
|
|
| SMD TET2 muté |
0 (0) |
1 (17) |
0 (0) |
1 (13) |
|
|
|
| Manquants |
15 |
1 |
10 |
26 |
|
|
|
| creat_ant, Median [IQR] |
145 [88 - 172] |
93 [73 - 114] |
97 [83 - 127] |
102 [83 - 153] |
0.15 |
32/34 |
|
| Manquants |
2 |
0 |
0 |
2 |
|
|
|
| creat_peak, Median [IQR] |
513 [383 - 567] |
364 [256 - 471] |
301 [226 - 501] |
425 [258 - 536] |
0.20 |
34/34 |
|
| RPCu (g/g), Median [IQR] |
1.20 [0.71 - 2.67] |
1.75 [0.78 - 3.33] |
0.80 [0.50 - 1.80] |
1.10 [0.60 - 2.45] |
0.51 |
31/34 |
|
| Manquants |
2 |
1 |
0 |
3 |
|
|
|
| RACu (g/g), Median [IQR] |
0.38 [0.11 - 1.60] |
0.28 [0.16 - 0.66] |
0.16 [0.09 - 1.12] |
0.27 [0.11 - 1.45] |
0.50 |
28/34 |
|
| Manquants |
3 |
2 |
1 |
6 |
|
|
|
| AlbU/ProtU, Median [IQR] |
37 [16 - 54] |
27 [22 - 30] |
19 [14 - 58] |
24 [16 - 48] |
0.77 |
28/34 |
|
| Manquants |
3 |
2 |
1 |
6 |
|
|
|
| leucocytU, Median [IQR] |
38,000 [17,750 - 128,500] |
36,000 [13,000 - 52,250] |
51,000 [29,000 - 91,500] |
50,000 [18,500 - 101,500] |
0.79 |
31/34 |
|
| Manquants |
2 |
1 |
0 |
3 |
|
|
|
| leucoUsupegal10000, n (%) |
|
|
|
|
>0.99 |
31/34 |
|
| non |
2 (14) |
1 (17) |
1 (9.1) |
4 (13) |
|
|
|
| oui |
12 (86) |
5 (83) |
10 (91) |
27 (87) |
|
|
|
| Manquants |
2 |
1 |
0 |
3 |
|
|
|
| leucoUsupe10000, n (%) |
|
|
|
|
0.71 |
31/34 |
|
| non |
2 (14) |
2 (33) |
2 (18) |
6 (19) |
|
|
|
| oui |
12 (86) |
4 (67) |
9 (82) |
25 (81) |
|
|
|
| Manquants |
2 |
1 |
0 |
3 |
|
|
|
| creat_lastFU, Median [IQR] |
249 [138 - 287] |
138 [102 - 198] |
170 [120 - 241] |
184 [118 - 261] |
0.18 |
34/34 |
|
| synthese_nephropathie, n (%) |
|
|
|
|
0.082 |
34/34 |
|
| Amylose AL / fibrose inflammatoire |
1 (6.3) |
0 (0) |
0 (0) |
1 (2.9) |
|
|
|
| GNMP / fibrose inflammatoire |
1 (6.3) |
0 (0) |
0 (0) |
1 (2.9) |
|
|
|
| GNMP ou GNPI |
1 (6.3) |
0 (0) |
0 (0) |
1 (2.9) |
|
|
|
| HSF II sur néphropathie vasculaire / infiltrat |
0 (0) |
0 (0) |
1 (9.1) |
1 (2.9) |
|
|
|
| NIA granulomateuse |
0 (0) |
0 (0) |
1 (9.1) |
1 (2.9) |
|
|
|
| NIA satellite de LMMC |
0 (0) |
1 (14) |
0 (0) |
1 (2.9) |
|
|
|
| NIA-PNN |
1 (6.3) |
4 (57) |
4 (36) |
9 (26) |
|
|
|
| NIA-PNN / PyPA |
10 (63) |
2 (29) |
3 (27) |
15 (44) |
|
|
|
| NIA-PNN /PyPA |
1 (6.3) |
0 (0) |
0 (0) |
1 (2.9) |
|
|
|
| NIA-PNN, granulomes |
0 (0) |
0 (0) |
1 (9.1) |
1 (2.9) |
|
|
|
| NTIC / fibrose inflammatoire |
1 (6.3) |
0 (0) |
0 (0) |
1 (2.9) |
|
|
|
| NTIC-PNN, HSF II |
0 (0) |
0 (0) |
1 (9.1) |
1 (2.9) |
|
|
|
| pnnmax (/mm3), Median [IQR] |
7,330 [4,495 - 12,140] |
7,525 [5,588 - 8,488] |
5,480 [5,040 - 7,480] |
6,600 [4,980 - 8,900] |
0.52 |
33/34 |
|
| Manquants |
0 |
1 |
0 |
1 |
|
|
|
| hpnn, n (%) |
9 (56) |
3 (50) |
3 (27) |
15 (45) |
0.38 |
33/34 |
|
| Manquants |
0 |
1 |
0 |
1 |
|
|
|
| crpmax (mg/l), Median [IQR] |
65 [13 - 212] |
58 [12 - 97] |
19 [0 - 32] |
31 [2 - 128] |
0.36 |
25/34 |
|
| Manquants |
5 |
2 |
2 |
9 |
|
|
|
| NGSpbr_variantgene, n (%) |
|
|
|
|
0.002 |
16/34 |
|
| 0 |
0 (NA) |
0 (0) |
6 (67) |
6 (38) |
|
|
|
| DNMT3A |
0 (NA) |
3 (43) |
0 (0) |
3 (19) |
|
|
|
| DNMT3A/TET2/SRSF2 |
0 (NA) |
1 (14) |
0 (0) |
1 (6.3) |
|
|
|
| DNMT3Afs |
0 (NA) |
0 (0) |
1 (11) |
1 (6.3) |
|
|
|
| SRSF2/TET2 |
0 (NA) |
1 (14) |
0 (0) |
1 (6.3) |
|
|
|
| TET2 |
0 (NA) |
0 (0) |
2 (22) |
2 (13) |
|
|
|
| TET2/DNMT3A/CBL |
0 (NA) |
1 (14) |
0 (0) |
1 (6.3) |
|
|
|
| TET2/RUNX1/SRSF2/TET2/MPL/PTPN11 |
0 (NA) |
1 (14) |
0 (0) |
1 (6.3) |
|
|
|
| Manquants |
16 |
0 |
2 |
18 |
|
|
|
| FIAT diffus = 90, Median [IQR] |
0.70 [0.50 - 0.90] |
0.40 [0.33 - 0.48] |
0.25 [0.16 - 0.58] |
0.50 [0.25 - 0.70] |
0.037 |
31/34 |
|
| Manquants |
1 |
1 |
1 |
3 |
|
|
|
| FIAT, n (%) |
|
|
|
|
0.028 |
31/34 |
|
| 0 |
2 (13) |
0 (0) |
2 (20) |
4 (13) |
|
|
|
| 1 |
0 (0) |
1 (17) |
3 (30) |
4 (13) |
|
|
|
| 2 |
1 (6.7) |
3 (50) |
1 (10) |
5 (16) |
|
|
|
| 3 |
12 (80) |
2 (33) |
4 (40) |
18 (58) |
|
|
|
| Manquants |
1 |
1 |
1 |
3 |
|
|
|
| FIAT2, n (%) |
|
|
|
|
0.11 |
31/34 |
|
| FIAT 0-1 |
2 (13) |
1 (17) |
5 (50) |
8 (26) |
|
|
|
| FIAT 2-3 |
13 (87) |
5 (83) |
5 (50) |
23 (74) |
|
|
|
| Manquants |
1 |
1 |
1 |
3 |
|
|
|