Statistical analysis
The following columns are used for analysis:
| Study ID |
| Device Type |
| Likert Score SS MDE SSFP- R1 (PN) |
| Likert Score SS MDE SPGR- R1 (PN) |
| Likert Score Segmented MDE SPGR- R1 (PN) |
| Likert Score SS MDE SSFP R-2 (JS) |
| Likert Score SS MDE SPGR R-2 (JS) |
| Likert Score Segmented MDE SPGR R-2 (JS) |
| LGE accuracy - Detection on SSFP SS MDE (compare to gold standard - segmented SPGR) - R1 (PN) |
| LGE accuracy - Detection SPGR SS MDE (compare to gold standard - segmented SPGR) - R1 (PN) |
| LGE accuracy - Detection SS SSFP (compare to gold standard - segmented SPGR) - R2 (JS) |
| LGE accuracy - Detection SS SPGR (compare to gold standard - segmented SPGR) - R2 (JS) |
| SNR Blood -SS-SSFP |
| SNR Myocardium-SS-SSFP |
| CNR blood-myo (Signal Blood - Signal Myo / SD Blood) SS-SSFP |
| SNR Blood SS-SPGR |
| SNR Myocardium SS-SPGR |
| CNR blood-myo (Signal Blood - Signal Myo / SD Blood) SS-SPGR |
| SNR Blood Seg-SPGR |
| SNR Myocardium Seg SPGR |
| CNR blood-myo (Signal Blood - Signal Myo / SD Blood) Seg-SPGR |
| ICD |
10 |
| No Device |
3 |
| PM |
3 |
| S-ICD |
3 |
Inter-rater agreement
The inter-reader agreement between PN and JS is measured by the intra-class correlation coefficient (ICC) and its 95% confidence interval (CI). The results are summarized below.
| 0.907 (0.78, 0.963), p<0.001 |
0.52 (0.109, 0.782), p=0.008 |
0.743 (0.454, 0.892), p<0.001 |
0.801 (0.561, 0.918), p<0.001 |
0.699 (0.379, 0.871), p<0.001 |
The overall ICC (95% CI) is 0.847 (0.779, 0.896), p<0.001, suggesting strong inter-reader agreement.
Likert scores and LGE
The mean Likert score (1-5) and LGE score (1-4) are summarized by mean (SD, standard deviation) and compared across methods by repeated measures ANOVA test.
All (n=19)
| Likert |
PN |
3.1 (1.4) |
2.1 (0.8) |
1.6 (0.7) |
<0.001 |
| Likert |
JS |
3.3 (1.4) |
1.9 (0.7) |
1.7 (0.7) |
<0.001 |
| LGE |
PN |
2.7 (1.1) |
1.9 (0.7) |
NA |
0.005 |
| LGE |
JS |
2.9 (0.9) |
1.7 (0.7) |
NA |
<0.001 |
ICD (n=13)
| Likert |
PN |
3.9 (0.8) |
2.3 (0.8) |
1.8 (0.7) |
<0.001 |
| Likert |
JS |
4 (1) |
2.1 (0.8) |
1.7 (0.8) |
<0.001 |
| LGE |
PN |
3.3 (0.6) |
2.1 (0.6) |
NA |
<0.001 |
| LGE |
JS |
3.3 (0.8) |
1.8 (0.8) |
NA |
<0.001 |
PM (n=3)
| Likert |
PN |
1.3 (0.6) |
1.3 (0.6) |
1.3 (0.6) |
1 |
| Likert |
JS |
1.7 (0.6) |
1.3 (0.6) |
2 (1) |
0.64 |
| LGE |
PN |
1.3 (0.6) |
1.7 (1.2) |
NA |
0.423 |
| LGE |
JS |
2 (1) |
1.3 (0.6) |
NA |
0.184 |
SNR blood, myo, and CNR blood-myo
Similarly, SNR blood, myo, and CNR blood-myo are summarized by mean (SD) and tested across methods by repeated measures ANOVA.
All (n=19)
| SNRblood |
9.4 (10.2) |
11.2 (2.4) |
16.8 (6.4) |
0.007 |
| SNRmyo |
3.4 (3.1) |
2.4 (1.7) |
2.9 (2.3) |
0.25 |
| CNR |
7.9 (9.4) |
9.4 (2.3) |
14.5 (5.6) |
0.006 |
ICD (n=13)
| SNRblood |
4.9 (5.6) |
10.9 (2.7) |
16.2 (6.3) |
<0.001 |
| SNRmyo |
3.9 (3.7) |
2.6 (1.8) |
3.2 (2.3) |
0.306 |
| CNR |
3.5 (4) |
9 (2.3) |
13.8 (6.1) |
<0.001 |
PM (n=3)
| SNRblood |
22.4 (16) |
11 (1.6) |
21 (9.7) |
0.495 |
| SNRmyo |
2.5 (1.7) |
1 (1.1) |
1.9 (3.8) |
0.475 |
| CNR |
20.4 (15.7) |
10.1 (1.9) |
18.5 (5.1) |
0.464 |
There are significant differences in SNRblood and CNR, with SSFP < SPGR < Seg. There is no significant difference in SNRmyo.