This study mainly focuses on doing an enrichment analysis for the DD genes (overall) to see if the 2nd mode (higher mean) shows enrichment for one or more of the 4 clusters.

I did a chi-squared test based on 4 MZ cotwins clusters with 2 components, and filtered 195 genes from all 3710 DD genes. The table below shows the associated parameters for each gene.

1) Enrichment of MZ Cotwins Clusters in the 2nd Mode for the Overall DD Genes

2) Enrichment of MZ Cotwins Clusters in the 2nd Mode for the Overall DD Genes Overlapped with Discordant_B DE Genes