MCCC2 High (N=267)	MCCC2 Low (N=268)	P-value
sex
FEMALE	98 (36.7%)	88 (32.8%)	0.396
MALE	169 (63.3%)	180 (67.2%)
age
older	139 (52.1%)	129 (48.1%)	0.411
younger	128 (47.9%)	139 (51.9%)
stage
I/II	179 (67.0%)	150 (56.0%)	0.011
III/IV	88 (33.0%)	118 (44.0%)
grade
G1	8 (3.0%)	6 (2.2%)	0.165
G2	120 (44.9%)	111 (41.4%)
G3	109 (40.8%)	100 (37.3%)
G4	28 (10.5%)	47 (17.5%)
GX	2 (0.7%)	4 (1.5%)
T
T1/2	184 (68.9%)	161 (60.1%)	0.0408
T3/4	83 (31.1%)	107 (39.9%)
N
N0	120 (44.9%)	120 (44.8%)	0.882
N1	7 (2.6%)	9 (3.4%)
NX	140 (52.4%)	139 (51.9%)
M
M0	218 (81.6%)	206 (76.9%)	0.331
M1	33 (12.4%)	45 (16.8%)
MX	16 (6.0%)	17 (6.3%)
pharmaceutical
NO	242 (90.6%)	218 (81.3%)	0.00297
YES	25 (9.4%)	50 (18.7%)
smoking
less	154 (57.7%)	147 (54.9%)	0.567
more	113 (42.3%)	121 (45.1%)
Event
0	203 (76.0%)	159 (59.3%)	<0.001
1	64 (24.0%)	109 (40.7%)