RASSF8 High (N=267)	RASSF8 Low (N=268)	P-value
sex
FEMALE	91 (34.1%)	95 (35.4%)	0.81
MALE	176 (65.9%)	173 (64.6%)
age
older	131 (49.1%)	137 (51.1%)	0.697
younger	136 (50.9%)	131 (48.9%)
stage
I/II	176 (65.9%)	153 (57.1%)	0.0445
III/IV	91 (34.1%)	115 (42.9%)
grade
G1	7 (2.6%)	7 (2.6%)	0.167
G2	126 (47.2%)	105 (39.2%)
G3	103 (38.6%)	106 (39.6%)
G4	29 (10.9%)	46 (17.2%)
GX	2 (0.7%)	4 (1.5%)
T
T1/2	182 (68.2%)	163 (60.8%)	0.0921
T3/4	85 (31.8%)	105 (39.2%)
N
N0	120 (44.9%)	120 (44.8%)	0.882
N1	7 (2.6%)	9 (3.4%)
NX	140 (52.4%)	139 (51.9%)
M
M0	221 (82.8%)	203 (75.7%)	0.0419
M1	36 (13.5%)	42 (15.7%)
MX	10 (3.7%)	23 (8.6%)
pharmaceutical
NO	244 (91.4%)	216 (80.6%)	<0.001
YES	23 (8.6%)	52 (19.4%)
smoking
less	149 (55.8%)	152 (56.7%)	0.9
more	118 (44.2%)	116 (43.3%)
Event
0	194 (72.7%)	168 (62.7%)	0.0176
1	73 (27.3%)	100 (37.3%)