DCB (N=7)	NDB (N=12)	P-value
Age
Mean (SD)	56.3 (10.6)	59.1 (8.02)	0.661
Median [Min, Max]	59.0 [34.0, 66.0]	59.0 [42.0, 69.0]
Gender
Female	2 (28.6%)	6 (50.0%)	0.667
Male	5 (71.4%)	6 (50.0%)
ECOG
0	1 (14.3%)	4 (33.3%)	0.712
1	6 (85.7%)	8 (66.7%)
Number.of.metastatic.site
>=2	4 (57.1%)	10 (83.3%)	0.477
0-1	3 (42.9%)	2 (16.7%)
Previous_immunotherapy
No	4 (57.1%)	7 (58.3%)	1
Yes	3 (42.9%)	5 (41.7%)
Lines.of.therapy
>=2	5 (71.4%)	8 (66.7%)	1
0-1	2 (28.6%)	4 (33.3%)
dNLR
<=3	6 (85.7%)	9 (75.0%)	1
>3	1 (14.3%)	3 (25.0%)
LDH
<=ULN	5 (71.4%)	6 (50.0%)	0.667
>ULN	2 (28.6%)	6 (50.0%)
Albumin
<3.5 g/dL	0 (0%)	2 (16.7%)	0.714
>=3.5 g/dL	7 (100%)	10 (83.3%)
Liver.metastasis
no	5 (71.4%)	8 (66.7%)	1
yes	2 (28.6%)	4 (33.3%)
Previous_radiation_therapy
No	4 (57.1%)	9 (75.0%)	0.767
Yes	3 (42.9%)	3 (25.0%)
Smoking_history
No	4 (57.1%)	7 (58.3%)	1
Yes	3 (42.9%)	5 (41.7%)
BMI
Mean (SD)	22.3 (3.05)	23.8 (4.39)	0.395
Median [Min, Max]	24.1 [17.3, 25.4]	22.3 [17.0, 33.9]
ICI_response
PR	3 (42.9%)	0 (0%)	0.013
SD	4 (57.1%)	6 (50.0%)
PD	0 (0%)	6 (50.0%)