| Gain (N=7) |
Diploid (N=25) |
P-value | |
|---|---|---|---|
| Age | |||
| Mean (SD) | 40.3 (9.21) | 44.3 (7.80) | 0.149 |
| Median [Min, Max] | 38.0 [32.0, 58.0] | 43.0 [32.0, 61.0] | |
| Gender | |||
| Female | 0 (0%) | 6 (24.0%) | 0.373 |
| Male | 7 (100%) | 19 (76.0%) | |
| ECOG | |||
| 0 | 4 (57.1%) | 10 (40.0%) | 0.706 |
| 1 | 3 (42.9%) | 15 (60.0%) | |
| Number.of.metastatic.site | |||
| >=2 | 7 (100%) | 24 (96.0%) | 1 |
| 0-1 | 0 (0%) | 1 (4.0%) | |
| Previous_immunotherapy | |||
| N | 3 (42.9%) | 12 (48.0%) | 1 |
| Y | 4 (57.1%) | 13 (52.0%) | |
| Lines.of.therapy | |||
| >=2 | 7 (100%) | 21 (84.0%) | 0.628 |
| 0-1 | 0 (0%) | 4 (16.0%) | |
| dNLR | |||
| <=3 | 6 (85.7%) | 20 (80.0%) | 1 |
| >3 | 1 (14.3%) | 5 (20.0%) | |
| LDH | |||
| <=ULN | 3 (42.9%) | 11 (44.0%) | 1 |
| >ULN | 4 (57.1%) | 14 (56.0%) | |
| Albumin | |||
| <3.5 g/dL | 0 (0%) | 1 (4.0%) | 1 |
| >=3.5 g/dL | 7 (100%) | 24 (96.0%) | |
| Liver.metastasis | |||
| no | 3 (42.9%) | 11 (44.0%) | 1 |
| yes | 4 (57.1%) | 14 (56.0%) | |
| Previous_radiation_therapy | |||
| N | 1 (14.3%) | 4 (16.0%) | 1 |
| Y | 6 (85.7%) | 21 (84.0%) | |
| Smoking_history | |||
| No | 6 (85.7%) | 19 (76.0%) | 0.974 |
| Yes | 1 (14.3%) | 6 (24.0%) | |
| BMI | |||
| Mean (SD) | 23.3 (3.14) | 21.7 (2.76) | 0.459 |
| Median [Min, Max] | 22.5 [20.0, 29.0] | 21.6 [17.8, 29.3] | |
| ICI_response | |||
| PR | 0 (0%) | 7 (28.0%) | 0.048 |
| SD | 0 (0%) | 6 (24.0%) | |
| PD | 7 (100%) | 10 (40.0%) | |
| Missing | 0 (0%) | 2 (8.0%) |