Draft

Univariate model for Anemia_g2_90days

Characteristic	N	Univariate logistic regression
		OR1	95% CI1	p-value
cancer_type	1,340
advanced lung		—	—
bladder		1.43	1.10, 1.87	0.008
breast		2.06	1.02, 4.41	0.051
head_neck		1.19	0.54, 2.69	0.67
Head_neck		1.32	0.77, 2.32	0.32
lung		2.37	1.20, 5.03	0.017
Meso		0.57	0.34, 0.93	0.027
NSCLC		0.90	0.53, 1.54	0.70
pancreatic		2.50	1.55, 4.16	<0.001
eGFR_CRE	1,321	0.99	0.98, 1.00	<0.001
ckd	1,321	2.39	1.63, 3.59	<0.001
Cisplatin_cat	653
<50		—	—
>75		0.39	0.25, 0.59	<0.001
50-74.9		0.65	0.45, 0.93	0.020
Age	1,340	1.00	0.99, 1.02	0.37
diu	1,340	1.40	1.12, 1.75	0.003
dm	1,340	1.31	1.05, 1.64	0.018
htn	1,340	0.89	0.69, 1.14	0.36
ppi	1,340	1.28	0.99, 1.65	0.061
steroids	1,340	1.40	1.12, 1.75	0.003
smoking	1,340	1.11	0.88, 1.40	0.39
cad	1,340	1.23	0.99, 1.53	0.061
Male	1,340	0.57	0.46, 0.71	<0.001
Race	1,340
Asian		—	—
Black		1.47	0.60, 3.69	0.40
Other/Unknown		0.97	0.43, 2.15	0.93
White		1.15	0.62, 2.11	0.64
BMI	1,188	0.98	0.96, 1.00	0.050
sarcopenia	1,340	1.84	1.41, 2.41	<0.001
1 OR = Odds Ratio, CI = Confidence Interval

Univariate model for Anemia_g3_90days

Characteristic	N	Univariate logistic regression
		OR1	95% CI1	p-value
cancer_type	1,340
advanced lung		—	—
bladder		1.19	0.85, 1.64	0.30
breast		1.05	0.41, 2.32	0.92
head_neck		1.99	0.80, 4.56	0.12
Head_neck		0.93	0.43, 1.83	0.85
lung		2.08	1.01, 4.08	0.037
Meso		0.91	0.45, 1.70	0.78
NSCLC		0.81	0.36, 1.62	0.57
pancreatic		1.93	1.17, 3.13	0.008
eGFR_CRE	1,321	0.99	0.98, 1.00	0.019
ckd	1,321	1.98	1.34, 2.88	<0.001
Cisplatin_cat	653
<50		—	—
>75		0.70	0.41, 1.17	0.18
50-74.9		0.85	0.56, 1.30	0.45
Age	1,340	1.01	0.99, 1.02	0.39
diu	1,340	1.43	1.08, 1.91	0.014
dm	1,340	1.19	0.90, 1.55	0.22
htn	1,340	1.18	0.87, 1.62	0.29
ppi	1,340	1.31	0.95, 1.85	0.11
steroids	1,340	1.43	1.08, 1.91	0.014
smoking	1,340	1.15	0.86, 1.54	0.35
cad	1,340	1.34	1.02, 1.75	0.033
Male	1,340	0.63	0.48, 0.83	<0.001
Race	1,340
Asian		—	—
Black		0.92	0.34, 2.43	0.86
Other/Unknown		0.54	0.21, 1.39	0.20
White		0.59	0.31, 1.18	0.11
BMI	1,188	0.98	0.96, 1.01	0.15
sarcopenia	1,340	1.69	1.25, 2.26	<0.001
1 OR = Odds Ratio, CI = Confidence Interval

Univariate model for Anemia_clinical_90days

Characteristic	N	Univariate logistic regression
		OR1	95% CI1	p-value
cancer_type	1,319
advanced lung		—	—
bladder		0.85	0.60, 1.20	0.36
breast		0.64	0.22, 1.55	0.37
head_neck		2.57	1.10, 5.74	0.023
Head_neck		0.88	0.41, 1.72	0.71
lung		1.70	0.81, 3.36	0.14
Meso		0.33	0.11, 0.76	0.019
NSCLC		1.05	0.52, 1.98	0.88
pancreatic		2.19	1.35, 3.51	0.001
eGFR_CRE	1,316	0.99	0.99, 1.00	0.036
ckd	1,316	2.01	1.36, 2.93	<0.001
Cisplatin_cat	641
<50		—	—
>75		0.56	0.32, 0.95	0.035
50-74.9		0.55	0.35, 0.86	0.008
Age	1,319	1.00	0.99, 1.02	0.53
diu	1,319	1.36	1.02, 1.82	0.038
dm	1,319	1.27	0.96, 1.67	0.087
htn	1,319	0.94	0.70, 1.28	0.69
ppi	1,319	1.37	0.98, 1.95	0.071
steroids	1,319	1.36	1.02, 1.82	0.038
smoking	1,319	1.23	0.92, 1.67	0.17
cad	1,319	1.13	0.86, 1.49	0.37
Male	1,319	0.81	0.61, 1.06	0.12
Race	1,319
Asian		—	—
Black		0.41	0.12, 1.24	0.13
Other/Unknown		0.31	0.10, 0.88	0.032
White		0.59	0.31, 1.19	0.12
BMI	1,171	0.96	0.93, 0.99	0.004
sarcopenia	1,319	1.83	1.36, 2.46	<0.001
1 OR = Odds Ratio, CI = Confidence Interval

Univariate model for Throm_g2_90days

Characteristic	N	Univariate logistic regression
		OR1	95% CI1	p-value
cancer_type	1,340
advanced lung		—	—
bladder		2.05	1.45, 2.91	<0.001
breast		3.87	1.84, 7.84	<0.001
head_neck		2.15	0.76, 5.23	0.11
Head_neck		2.07	1.03, 3.92	0.032
lung		1.47	0.58, 3.26	0.37
Meso		0.32	0.08, 0.88	0.056
NSCLC		0.96	0.39, 2.07	0.93
pancreatic		2.93	1.74, 4.84	<0.001
eGFR_CRE	1,321	0.99	0.98, 1.00	0.002
ckd	1,321	1.81	1.19, 2.69	0.004
Cisplatin_cat	653
<50		—	—
>75		0.32	0.17, 0.58	<0.001
50-74.9		0.74	0.49, 1.12	0.16
Age	1,340	1.00	0.99, 1.02	0.65
diu	1,340	1.46	1.08, 1.99	0.016
dm	1,340	1.41	1.06, 1.87	0.020
htn	1,340	1.26	0.90, 1.77	0.18
ppi	1,340	0.99	0.71, 1.39	0.93
steroids	1,340	1.46	1.08, 1.99	0.016
smoking	1,340	1.20	0.88, 1.64	0.26
cad	1,340	1.19	0.90, 1.59	0.22
Male	1,340	0.94	0.71, 1.26	0.69
Race	1,340
Asian		—	—
Black		0.68	0.21, 2.06	0.50
Other/Unknown		0.87	0.33, 2.32	0.78
White		0.69	0.35, 1.49	0.31
BMI	1,188	1.02	1.00, 1.05	0.062
sarcopenia	1,340	1.69	1.24, 2.30	<0.001
1 OR = Odds Ratio, CI = Confidence Interval

Univariate model for Throm_g3_90days

Characteristic	N	Univariate logistic regression
		OR1	95% CI1	p-value
cancer_type	1,340
advanced lung		—	—
bladder		1.81	1.14, 2.90	0.013
breast		2.32	0.76, 5.85	0.10
head_neck		1.94	0.45, 5.91	0.30
Head_neck		2.04	0.80, 4.56	0.10
lung		2.06	0.68, 5.15	0.15
Meso		0.66	0.16, 1.88	0.49
NSCLC		0.80	0.19, 2.30	0.71
pancreatic		3.57	1.90, 6.51	<0.001
eGFR_CRE	1,321	0.98	0.97, 0.99	<0.001
ckd	1,321	1.99	1.18, 3.22	0.007
Cisplatin_cat	653
<50		—	—
>75		0.39	0.17, 0.81	0.017
50-74.9		0.71	0.42, 1.20	0.20
Age	1,340	1.00	0.98, 1.02	0.95
diu	1,340	1.59	1.07, 2.44	0.027
dm	1,340	1.62	1.11, 2.36	0.011
htn	1,340	1.40	0.90, 2.25	0.15
ppi	1,340	1.22	0.78, 1.98	0.41
steroids	1,340	1.59	1.07, 2.44	0.027
smoking	1,340	1.22	0.81, 1.86	0.35
cad	1,340	1.36	0.94, 1.98	0.11
Male	1,340	0.86	0.59, 1.25	0.42
Race	1,340
Asian		—	—
Black		0.37	0.05, 1.74	0.25
Other/Unknown		0.65	0.17, 2.30	0.50
White		0.62	0.28, 1.67	0.29
BMI	1,188	1.02	0.98, 1.05	0.37
sarcopenia	1,340	1.68	1.11, 2.49	0.011
1 OR = Odds Ratio, CI = Confidence Interval

Univariate model for Throm_clinical_90days

Characteristic	N	Univariate logistic regression
		OR1	95% CI1	p-value
cancer_type	1,322
advanced lung		—	—
bladder		1.13	0.86, 1.47	0.38
breast		1.79	0.92, 3.55	0.090
head_neck		1.59	0.72, 3.55	0.25
Head_neck		1.18	0.68, 2.05	0.56
lung		1.18	0.62, 2.22	0.62
Meso		0.82	0.49, 1.37	0.46
NSCLC		1.00	0.58, 1.72	>0.99
pancreatic		1.33	0.86, 2.07	0.20
eGFR_CRE	1,321	1.00	0.99, 1.00	0.58
ckd	1,321	1.33	0.94, 1.88	0.11
Cisplatin_cat	641
<50		—	—
>75		0.63	0.41, 0.96	0.033
50-74.9		0.88	0.62, 1.25	0.47
Age	1,322	1.01	1.0, 1.02	0.32
diu	1,322	1.46	1.17, 1.84	<0.001
dm	1,322	1.06	0.85, 1.33	0.60
htn	1,322	1.00	0.78, 1.28	0.98
ppi	1,322	1.19	0.92, 1.55	0.19
steroids	1,322	1.46	1.17, 1.84	<0.001
smoking	1,322	1.28	1.02, 1.63	0.036
cad	1,322	1.21	0.97, 1.50	0.090
Male	1,322	0.79	0.63, 0.98	0.034
Race	1,322
Asian		—	—
Black		1.01	0.41, 2.50	0.98
Other/Unknown		0.86	0.38, 1.98	0.72
White		1.31	0.71, 2.47	0.40
BMI	1,173	0.98	0.96, 1.00	0.11
sarcopenia	1,322	1.53	1.19, 1.98	0.001
1 OR = Odds Ratio, CI = Confidence Interval

Univariate model for Neutro_g2_90days

Characteristic	N	Univariate logistic regression
		OR1	95% CI1	p-value
cancer_type	1,319
advanced lung		—	—
bladder		3.32	2.49, 4.44	<0.001
breast		4.64	2.36, 9.23	<0.001
head_neck		1.75	0.70, 4.00	0.20
Head_neck		2.07	1.14, 3.66	0.013
lung		1.83	0.89, 3.57	0.085
Meso		0.89	0.44, 1.67	0.73
NSCLC		2.78	1.57, 4.85	<0.001
pancreatic		1.37	0.81, 2.25	0.22
eGFR_CRE	1,312	0.99	0.98, 0.99	<0.001
ckd	1,312	1.73	1.21, 2.45	0.003
Cisplatin_cat	641
<50		—	—
>75		1.17	0.74, 1.84	0.51
50-74.9		2.63	1.82, 3.82	<0.001
Age	1,319	1.00	0.99, 1.01	0.58
diu	1,319	1.29	1.01, 1.65	0.044
dm	1,319	1.29	1.02, 1.64	0.036
htn	1,319	1.04	0.80, 1.36	0.79
ppi	1,319	0.82	0.63, 1.08	0.16
steroids	1,319	1.29	1.01, 1.65	0.044
smoking	1,319	0.90	0.70, 1.15	0.39
cad	1,319	0.89	0.70, 1.12	0.32
Male	1,319	0.84	0.67, 1.06	0.15
Race	1,319
Asian		—	—
Black		2.39	0.95, 6.18	0.067
Other/Unknown		1.11	0.45, 2.76	0.82
White		1.16	0.61, 2.37	0.67
BMI	1,170	1.01	0.99, 1.03	0.48
sarcopenia	1,319	0.95	0.72, 1.25	0.73
1 OR = Odds Ratio, CI = Confidence Interval

Univariate model for Neutro_g3_90days

Characteristic	N	Univariate logistic regression
		OR1	95% CI1	p-value
cancer_type	1,319
advanced lung		—	—
bladder		2.96	2.07, 4.26	<0.001
breast		3.79	1.72, 7.90	<0.001
head_neck		1.63	0.46, 4.44	0.38
Head_neck		2.34	1.13, 4.54	0.016
lung		2.17	0.90, 4.72	0.063
Meso		1.08	0.43, 2.34	0.85
NSCLC		3.13	1.60, 5.87	<0.001
pancreatic		1.59	0.82, 2.91	0.15
eGFR_CRE	1,312	0.99	0.98, 0.99	<0.001
ckd	1,312	1.95	1.29, 2.90	0.001
Cisplatin_cat	641
<50		—	—
>75		1.24	0.71, 2.14	0.45
50-74.9		2.14	1.38, 3.34	<0.001
Age	1,319	1.00	0.99, 1.02	0.65
diu	1,319	1.40	1.03, 1.92	0.033
dm	1,319	1.11	0.82, 1.49	0.50
htn	1,319	0.96	0.69, 1.34	0.79
ppi	1,319	0.86	0.62, 1.21	0.38
steroids	1,319	1.40	1.03, 1.92	0.033
smoking	1,319	0.84	0.62, 1.15	0.27
cad	1,319	0.99	0.74, 1.32	0.95
Male	1,319	0.94	0.70, 1.26	0.67
Race	1,319
Asian		—	—
Black		2.23	0.67, 8.06	0.20
Other/Unknown		1.24	0.37, 4.49	0.73
White		1.57	0.67, 4.60	0.35
BMI	1,170	1.01	0.99, 1.04	0.29
sarcopenia	1,319	0.96	0.68, 1.35	0.82
1 OR = Odds Ratio, CI = Confidence Interval

Univariate model for AKI_g2_90days

Characteristic	N	Univariate logistic regression
		OR1	95% CI1	p-value
cancer_type	1,321
advanced lung		—	—
bladder		1.60	1.11, 2.32	0.012
breast		0.90	0.26, 2.35	0.85
head_neck		0.97	0.23, 2.87	0.96
Head_neck		2.02	0.98, 3.91	0.044
lung		1.80	0.75, 3.88	0.16
Meso		2.28	1.20, 4.14	0.008
NSCLC		1.51	0.70, 3.01	0.26
pancreatic		1.00	0.48, 1.89	0.99
eGFR_CRE	1,321	1.00	1.00, 1.01	0.30
ckd	1,321	1.10	0.67, 1.73	0.71
Cisplatin_cat	640
<50		—	—
>75		2.45	1.41, 4.30	0.002
50-74.9		1.85	1.13, 3.09	0.017
Age	1,321	1.01	0.99, 1.02	0.36
diu	1,321	2.06	1.47, 2.93	<0.001
dm	1,321	1.20	0.88, 1.63	0.24
htn	1,321	1.47	1.03, 2.16	0.040
ppi	1,321	1.61	1.09, 2.45	0.020
steroids	1,321	2.06	1.47, 2.93	<0.001
smoking	1,321	1.02	0.74, 1.42	0.92
cad	1,321	1.21	0.90, 1.64	0.21
Male	1,321	0.60	0.44, 0.82	0.001
Race	1,321
Asian		—	—
Black		0.56	0.14, 1.97	0.38
Other/Unknown		0.67	0.22, 2.03	0.48
White		0.79	0.38, 1.86	0.56
BMI	1,172	1.03	1.00, 1.05	0.053
sarcopenia	1,321	1.49	1.06, 2.08	0.019
1 OR = Odds Ratio, CI = Confidence Interval

Univariate model for AKI_g3_90days

Characteristic	N	Univariate logistic regression
		OR1	95% CI1	p-value
cancer_type	1,321
advanced lung		—	—
bladder		2.16	0.47, 11.0	0.31
breast		0.00		>0.99
head_neck		0.00		>0.99
Head_neck		0.00		>0.99
lung		9.88	1.27, 61.3	0.014
Meso		5.84	0.76, 35.8	0.056
NSCLC		0.00		>0.99
pancreatic		4.23	0.55, 25.9	0.12
eGFR_CRE	1,321	0.96	0.93, 0.99	0.004
ckd	1,321	7.27	2.31, 22.2	<0.001
Cisplatin_cat	640
<50		—	—
>75		1.11	0.15, 6.78	0.91
50-74.9		0.87	0.16, 4.75	0.87
Age	1,321	0.99	0.95, 1.05	0.81
diu	1,321	2.02	0.61, 9.03	0.29
dm	1,321	1.35	0.43, 4.10	0.59
htn	1,321	31,422,775	0.00, NA	>0.99
ppi	1,321	3.56	0.70, 64.9	0.22
steroids	1,321	2.02	0.61, 9.03	0.29
smoking	1,321	1.56	0.47, 6.99	0.50
cad	1,321	1.39	0.46, 4.35	0.55
Male	1,321	0.50	0.15, 1.51	0.23
Race	1,321
Asian		—	—
Black		0.00		0.99
Other/Unknown		0.81	0.03, 20.9	0.88
White		0.40	0.08, 7.43	0.39
BMI	1,172	1.05	0.96, 1.13	0.18
sarcopenia	1,321	1.42	0.38, 4.41	0.56
1 OR = Odds Ratio, CI = Confidence Interval

Univariate model for AKI_clinical_90days

Characteristic	N	Univariate logistic regression
		OR1	95% CI1	p-value
cancer_type	1,321
advanced lung		—	—
bladder		2.30	1.20, 4.51	0.013
breast		0.00	0.00, 11,055,100,357,525	0.99
head_neck		0.00	0.00, 65,613,850,368,252,400	>0.99
Head_neck		2.00	0.45, 6.24	0.28
lung		2.79	0.63, 8.83	0.12
Meso		2.80	0.89, 7.43	0.052
NSCLC		1.24	0.19, 4.50	0.78
pancreatic		1.18	0.27, 3.62	0.80
eGFR_CRE	1,321	0.99	0.98, 1.01	0.36
ckd	1,321	1.45	0.62, 2.97	0.35
Cisplatin_cat	640
<50		—	—
>75		1.22	0.46, 3.10	0.67
50-74.9		1.29	0.59, 2.91	0.53
Age	1,321	1.00	0.98, 1.03	0.99
diu	1,321	2.74	1.42, 5.81	0.005
dm	1,321	1.49	0.86, 2.57	0.15
htn	1,321	2.95	1.35, 7.74	0.014
ppi	1,321	2.42	1.11, 6.36	0.044
steroids	1,321	2.74	1.42, 5.81	0.005
smoking	1,321	0.85	0.49, 1.54	0.59
cad	1,321	1.30	0.75, 2.25	0.35
Male	1,321	0.63	0.36, 1.09	0.10
Race	1,321
Asian		—	—
Black		0.80	0.10, 5.12	0.82
Other/Unknown		0.80	0.14, 4.54	0.80
White		0.55	0.19, 2.33	0.33
BMI	1,172	1.06	1.01, 1.10	0.006
sarcopenia	1,321	1.24	0.65, 2.23	0.49
1 OR = Odds Ratio, CI = Confidence Interval

Univariate model for SGOT_g2_90days

Characteristic	N	Univariate logistic regression
		OR1	95% CI1	p-value
cancer_type	1,454
advanced lung		—	—
bladder		0.29	0.11, 0.67	0.007
breast		1.56	0.36, 4.65	0.48
head_neck		0.78	0.04, 3.88	0.81
Head_neck		0.66	0.11, 2.28	0.58
lung		2.03	0.58, 5.48	0.21
Meso		0.81	0.19, 2.36	0.73
NSCLC		0.75	0.18, 2.18	0.64
pancreatic		1.54	0.60, 3.45	0.32
eGFR_CRE	1,350	1.01	1.00, 1.03	0.15
ckd	1,350	0.76	0.26, 1.76	0.57
Cisplatin_cat	750
<50		—	—
>75		0.78	0.27, 2.05	0.63
50-74.9		0.20	0.04, 0.63	0.013
Age	1,454	0.98	0.96, 1.01	0.22
diu	1,454	1.19	0.69, 2.13	0.54
dm	1,454	1.11	0.64, 1.89	0.71
htn	1,454	1.68	0.88, 3.56	0.14
ppi	1,454	5.75	2.10, 23.7	0.003
steroids	1,454	1.19	0.69, 2.13	0.54
smoking	1,454	0.99	0.57, 1.76	0.96
cad	1,454	1.76	1.03, 3.04	0.039
Male	1,454	0.65	0.38, 1.10	0.11
Race	1,454
Asian		—	—
Black		0.00	0.00, 48,013	0.98
Other/Unknown		0.35	0.07, 1.43	0.16
White		0.25	0.11, 0.67	0.002
BMI	1,294	0.96	0.91, 1.02	0.20
sarcopenia	1,454	2.18	1.24, 3.74	0.005
1 OR = Odds Ratio, CI = Confidence Interval

Univariate model for SGOT_g3_90days

Characteristic	N	Univariate logistic regression
		OR1	95% CI1	p-value
cancer_type	1,454
advanced lung		—	—
bladder		0.58	0.18, 1.58	0.31
breast		1.18	0.06, 6.24	0.87
head_neck		1.87	0.10, 10.0	0.56
Head_neck		0.00		0.99
lung		2.31	0.35, 8.85	0.28
Meso		1.28	0.20, 4.81	0.75
NSCLC		0.59	0.03, 3.03	0.61
pancreatic		2.05	0.56, 6.01	0.22
eGFR_CRE	1,350	1.01	0.99, 1.03	0.59
ckd	1,350	0.96	0.23, 2.78	0.95
Cisplatin_cat	750
<50		—	—
>75		0.67	0.14, 2.44	0.56
50-74.9		0.23	0.03, 0.96	0.068
Age	1,454	0.97	0.94, 1.01	0.13
diu	1,454	1.26	0.58, 2.93	0.58
dm	1,454	1.23	0.56, 2.60	0.60
htn	1,454	1.29	0.55, 3.54	0.58
ppi	1,454	22,052,527	0.00, NA	0.99
steroids	1,454	1.26	0.58, 2.93	0.58
smoking	1,454	0.88	0.41, 2.01	0.76
cad	1,454	2.29	1.07, 5.18	0.038
Male	1,454	0.78	0.37, 1.66	0.52
Race	1,454
Asian		—	—
Black		0.00		>0.99
Other/Unknown		0.00		>0.99
White		0.19	0.07, 0.67	0.003
BMI	1,294	0.96	0.87, 1.04	0.34
sarcopenia	1,454	3.44	1.61, 7.36	0.001
1 OR = Odds Ratio, CI = Confidence Interval

Univariate model for SGPT_g2_90days

Characteristic	N	Univariate logistic regression
		OR1	95% CI1	p-value
cancer_type	1,454
advanced lung		—	—
bladder		0.34	0.16, 0.65	0.002
breast		2.31	0.84, 5.46	0.075
head_neck		0.00	0.00, 33,421,721,413	0.98
Head_neck		0.45	0.07, 1.53	0.29
lung		0.66	0.11, 2.26	0.58
Meso		0.37	0.06, 1.22	0.17
NSCLC		0.51	0.12, 1.46	0.28
pancreatic		1.06	0.42, 2.29	0.90
eGFR_CRE	1,350	1.01	1.00, 1.03	0.072
ckd	1,350	0.72	0.27, 1.55	0.44
Cisplatin_cat	750
<50		—	—
>75		0.47	0.13, 1.36	0.20
50-74.9		0.43	0.16, 1.07	0.077
Age	1,454	0.97	0.95, 0.99	0.006
diu	1,454	0.93	0.57, 1.52	0.76
dm	1,454	0.92	0.55, 1.49	0.73
htn	1,454	1.24	0.72, 2.26	0.45
ppi	1,454	2.21	1.15, 4.82	0.028
steroids	1,454	0.93	0.57, 1.52	0.76
smoking	1,454	1.13	0.68, 1.92	0.65
cad	1,454	1.27	0.79, 2.04	0.33
Male	1,454	0.42	0.26, 0.69	<0.001
Race	1,454
Asian		—	—
Black		0.28	0.01, 1.98	0.26
Other/Unknown		0.56	0.11, 2.67	0.46
White		0.53	0.20, 1.79	0.23
BMI	1,294	0.99	0.94, 1.03	0.65
sarcopenia	1,454	1.21	0.69, 2.04	0.49
1 OR = Odds Ratio, CI = Confidence Interval

Univariate model for SGPT_g3_90days

Characteristic	N	Univariate logistic regression
		OR1	95% CI1	p-value
cancer_type	1,454
advanced lung		—	—
bladder		0.28	0.06, 0.85	0.043
breast		1.93	0.30, 7.18	0.39
head_neck		0.00	0.00, 32,306,665,681,633,146,830,068	>0.99
Head_neck		0.00	0.00, 3,157,882,769,032	0.99
lung		0.90	0.05, 4.60	0.92
Meso		0.50	0.03, 2.53	0.51
NSCLC		1.43	0.33, 4.46	0.58
pancreatic		1.63	0.46, 4.60	0.40
eGFR_CRE	1,350	1.01	0.99, 1.03	0.44
ckd	1,350	0.59	0.09, 1.99	0.47
Cisplatin_cat	750
<50		—	—
>75		0.67	0.14, 2.44	0.56
50-74.9		0.11	0.01, 0.65	0.043
Age	1,454	0.99	0.95, 1.02	0.39
diu	1,454	1.32	0.62, 3.08	0.49
dm	1,454	1.15	0.53, 2.42	0.71
htn	1,454	1.35	0.58, 3.69	0.51
ppi	1,454	8.77	1.86, 157	0.033
steroids	1,454	1.32	0.62, 3.08	0.49
smoking	1,454	1.56	0.70, 3.97	0.31
cad	1,454	1.79	0.86, 3.87	0.13
Male	1,454	0.47	0.21, 0.99	0.052
Race	1,454
Asian		—	—
Black		0.00	0.00, 569,815,928,964,160,320	0.99
Other/Unknown		0.38	0.02, 4.06	0.43
White		0.43	0.12, 2.75	0.27
BMI	1,294	0.95	0.87, 1.03	0.26
sarcopenia	1,454	2.41	1.11, 5.06	0.022
1 OR = Odds Ratio, CI = Confidence Interval

Univariate model for GCSF_90days

Characteristic	N	Univariate logistic regression
		OR1	95% CI1	p-value
cancer_type	1,454
advanced lung		—	—
bladder		2.00	1.45, 2.79	<0.001
breast		2.07	0.93, 4.24	0.057
head_neck		3.31	1.38, 7.47	0.005
Head_neck		2.45	1.31, 4.42	0.004
lung		2.49	1.19, 4.91	0.011
Meso		0.97	0.46, 1.89	0.94
NSCLC		1.68	0.91, 2.96	0.081
pancreatic		5.52	3.48, 8.77	<0.001
eGFR_CRE	1,350	1.00	0.99, 1.00	0.17
ckd	1,350	1.32	0.88, 1.95	0.17
Cisplatin_cat	750
<50		—	—
>75		0.90	0.57, 1.40	0.63
50-74.9		0.87	0.60, 1.27	0.48
Age	1,454	1.00	0.99, 1.01	0.70
diu	1,454	1.28	0.98, 1.68	0.077
dm	1,454	1.34	1.03, 1.73	0.028
htn	1,454	1.00	0.75, 1.34	>0.99
ppi	1,454	1.44	1.05, 2.00	0.027
steroids	1,454	1.28	0.98, 1.68	0.077
smoking	1,454	0.94	0.72, 1.23	0.65
cad	1,454	1.10	0.85, 1.42	0.47
Male	1,454	1.07	0.83, 1.39	0.59
Race	1,454
Asian		—	—
Black		0.85	0.31, 2.31	0.76
Other/Unknown		0.44	0.16, 1.18	0.11
White		0.70	0.37, 1.43	0.30
BMI	1,294	0.99	0.96, 1.01	0.24
sarcopenia	1,454	1.25	0.93, 1.68	0.13
1 OR = Odds Ratio, CI = Confidence Interval

Univariate cox model for anemia

Characteristic	N	Univariate cox regression cohort
		HR1	95% CI1	p-value
sarcopenia	1,454	1.57	1.35, 1.84	<0.001
cancer_type	1,454
advanced lung		—	—
bladder		0.99	0.84, 1.17	0.917
breast		1.17	0.78, 1.74	0.447
head_neck		1.13	0.67, 1.90	0.644
Head_neck		1.02	0.72, 1.45	0.893
lung		1.57	1.08, 2.29	0.018
Meso		0.57	0.39, 0.85	0.005
NSCLC		0.55	0.38, 0.80	0.002
pancreatic		1.79	1.38, 2.33	<0.001
eGFR_CRE	1,350	1.0	0.99, 1.00	0.008
Cisplatin_cat	750
<50		—	—
>75		0.49	0.37, 0.65	<0.001
50-74.9		0.67	0.54, 0.83	<0.001
Age	1,454	1.00	0.99, 1.01	0.701
diu	1,454	1.24	1.07, 1.44	0.004
dm	1,454	1.24	1.08, 1.43	0.003
htn	1,454	0.93	0.80, 1.09	0.385
ppi	1,454	1.26	1.06, 1.50	0.008
steroids	1,454	1.24	1.07, 1.44	0.004
smoking	1,454	1.14	0.98, 1.33	0.090
cad	1,454	1.28	1.12, 1.48	<0.001
Male	1,454	0.67	0.58, 0.77	<0.001
Race	1,454
Asian		—	—
Black		1.28	0.72, 2.26	0.405
Other/Unknown		0.92	0.53, 1.58	0.756
White		0.98	0.65, 1.47	0.926
BMI	1,294	0.98	0.96, 0.99	0.002
1 HR = Hazard Ratio, CI = Confidence Interval

Univariate cox model for aki

Characteristic	N	Univariate cox regression cohort
		HR1	95% CI1	p-value
sarcopenia	1,454	1.54	1.14, 2.08	0.005
cancer_type	1,454
advanced lung		—	—
bladder		1.32	0.94, 1.86	0.106
breast		0.79	0.29, 2.18	0.654
head_neck		0.98	0.31, 3.11	0.972
Head_neck		1.74	0.94, 3.21	0.078
lung		1.67	0.80, 3.48	0.168
Meso		1.80	1.05, 3.10	0.034
NSCLC		1.04	0.54, 2.03	0.900
pancreatic		0.95	0.50, 1.79	0.866
eGFR_CRE	1,350	1.00	1.00, 1.01	0.244
Cisplatin_cat	750
<50		—	—
>75		2.11	1.27, 3.49	0.004
50-74.9		1.63	1.02, 2.59	0.040
Age	1,454	1.01	0.99, 1.02	0.440
diu	1,454	1.93	1.39, 2.67	<0.001
dm	1,454	1.24	0.94, 1.65	0.131
htn	1,454	1.41	1.00, 2.00	0.050
ppi	1,454	1.63	1.12, 2.38	0.011
steroids	1,454	1.93	1.39, 2.67	<0.001
smoking	1,454	1.09	0.80, 1.47	0.591
cad	1,454	1.26	0.95, 1.67	0.104
Male	1,454	0.61	0.46, 0.81	<0.001
Race	1,454
Asian		—	—
Black		0.57	0.17, 1.88	0.355
Other/Unknown		0.66	0.24, 1.81	0.415
White		0.74	0.36, 1.50	0.398
BMI	1,294	1.02	1.00, 1.05	0.076
1 HR = Hazard Ratio, CI = Confidence Interval

Univariate cox model for throm

Characteristic	N	Univariate cox regression cohort
		HR1	95% CI1	p-value
sarcopenia	1,454	1.70	1.29, 2.24	<0.001
cancer_type	1,454
advanced lung		—	—
bladder		1.63	1.19, 2.23	0.002
breast		2.74	1.52, 4.95	<0.001
head_neck		1.90	0.83, 4.37	0.130
Head_neck		1.70	0.94, 3.06	0.079
lung		1.27	0.59, 2.76	0.544
Meso		0.30	0.09, 0.95	0.040
NSCLC		0.66	0.30, 1.44	0.296
pancreatic		2.46	1.58, 3.82	<0.001
eGFR_CRE	1,350	0.99	0.98, 1.00	0.002
Cisplatin_cat	750
<50		—	—
>75		0.36	0.20, 0.63	<0.001
50-74.9		0.75	0.52, 1.08	0.119
Age	1,454	1.00	0.99, 1.02	0.663
diu	1,454	1.38	1.04, 1.82	0.025
dm	1,454	1.39	1.07, 1.80	0.012
htn	1,454	1.20	0.88, 1.63	0.251
ppi	1,454	1.05	0.77, 1.42	0.770
steroids	1,454	1.38	1.04, 1.82	0.025
smoking	1,454	1.23	0.93, 1.64	0.150
cad	1,454	1.23	0.95, 1.60	0.111
Male	1,454	0.90	0.70, 1.17	0.443
Race	1,454
Asian		—	—
Black		0.66	0.24, 1.83	0.429
Other/Unknown		0.87	0.37, 2.04	0.747
White		0.67	0.36, 1.27	0.224
BMI	1,294	1.02	1.00, 1.04	0.111
1 HR = Hazard Ratio, CI = Confidence Interval

Univariate cox model for neutro

Characteristic	N	Univariate cox regression cohort
		HR1	95% CI1	p-value
sarcopenia	1,454	1.08	0.86, 1.37	0.501
cancer_type	1,454
advanced lung		—	—
bladder		1.59	1.24, 2.04	<0.001
breast		1.90	1.11, 3.25	0.019
head_neck		3.09	1.77, 5.37	<0.001
Head_neck		2.03	1.31, 3.14	0.002
lung		1.86	1.09, 3.19	0.023
Meso		0.88	0.50, 1.53	0.644
NSCLC		1.00	0.60, 1.66	0.995
pancreatic		1.82	1.25, 2.67	0.002
eGFR_CRE	1,350	0.99	0.99, 1.00	0.015
Cisplatin_cat	750
<50		—	—
>75		0.98	0.67, 1.44	0.927
50-74.9		1.38	1.02, 1.86	0.038
Age	1,454	1.00	0.99, 1.01	0.392
diu	1,454	1.08	0.88, 1.33	0.467
dm	1,454	1.36	1.11, 1.66	0.003
htn	1,454	1.09	0.86, 1.37	0.484
ppi	1,454	1.13	0.89, 1.45	0.313
steroids	1,454	1.08	0.88, 1.33	0.467
smoking	1,454	1.11	0.90, 1.38	0.334
cad	1,454	0.97	0.79, 1.19	0.775
Male	1,454	0.96	0.79, 1.18	0.702
Race	1,454
Asian		—	—
Black		0.90	0.41, 1.96	0.788
Other/Unknown		0.66	0.32, 1.39	0.278
White		0.78	0.47, 1.31	0.346
BMI	1,294	1.00	0.98, 1.02	0.806
1 HR = Hazard Ratio, CI = Confidence Interval

Univariate cox model for liver

Characteristic	N	Univariate cox regression cohort
		HR1	95% CI1	p-value
sarcopenia	1,454	1.46	0.96, 2.22	0.078
cancer_type	1,454
advanced lung		—	—
bladder		0.37	0.21, 0.65	<0.001
breast		1.80	0.82, 3.94	0.143
head_neck		0.39	0.05, 2.79	0.346
Head_neck		0.83	0.33, 2.08	0.693
lung		0.97	0.35, 2.67	0.952
Meso		0.40	0.13, 1.28	0.123
NSCLC		0.37	0.12, 1.19	0.094
pancreatic		0.98	0.49, 1.99	0.960
eGFR_CRE	1,350	1.01	1.00, 1.02	0.139
Cisplatin_cat	750
<50		—	—
>75		0.49	0.20, 1.23	0.128
50-74.9		0.42	0.20, 0.91	0.028
Age	1,454	0.97	0.96, 0.99	0.002
diu	1,454	0.87	0.58, 1.28	0.474
dm	1,454	0.77	0.51, 1.16	0.213
htn	1,454	1.30	0.81, 2.09	0.269
ppi	1,454	1.85	1.07, 3.20	0.027
steroids	1,454	0.87	0.58, 1.28	0.474
smoking	1,454	1.05	0.69, 1.58	0.825
cad	1,454	1.34	0.91, 1.97	0.139
Male	1,454	0.63	0.43, 0.93	0.019
Race	1,454
Asian		—	—
Black		0.14	0.02, 1.09	0.060
Other/Unknown		0.37	0.11, 1.24	0.107
White		0.37	0.18, 0.75	0.006
BMI	1,294	0.97	0.93, 1.01	0.135
1 HR = Hazard Ratio, CI = Confidence Interval