Gain (N=7)	Diploid (N=25)	P-value
Gender
Female	0 (0%)	6 (24.0%)	0.373
Male	7 (100%)	19 (76.0%)
Age
Mean (SD)	40.3 (9.21)	44.3 (7.80)	0.149
Median [Min, Max]	38.0 [32.0, 58.0]	43.0 [32.0, 61.0]
Previous_immunotherapy
N	3 (42.9%)	12 (48.0%)	1
Y	4 (57.1%)	13 (52.0%)
Previous_radiation_therapy
N	1 (14.3%)	4 (16.0%)	1
Y	6 (85.7%)	21 (84.0%)
Smoking_history
No	6 (85.7%)	19 (76.0%)	0.974
Yes	1 (14.3%)	6 (24.0%)
BMI
Mean (SD)	23.3 (3.14)	21.7 (2.76)	0.459
Median [Min, Max]	22.5 [20.0, 29.0]	21.6 [17.8, 29.3]
ICI_response
PR	0 (0%)	7 (28.0%)	0.048
SD	0 (0%)	6 (24.0%)
PD	7 (100%)	10 (40.0%)
Missing	0 (0%)	2 (8.0%)