Imputation using MOFA for Batch Corrected Data

Load libraries

suppressPackageStartupMessages({library(MOFA2)
library(kableExtra)
library(data.table)
library(ggplot2)
library(tidyverse)
library(here)})

Load data and Generate Mofa object

set.seed(1)
knitr::opts_chunk$set(warning = FALSE, message = FALSE)

add_cols <- function(df, cols) {
  add <- cols[!cols %in% names(df)]
  if(length(add) != 0) df[add] <- NA
  return(as.matrix(df[, sort(cols)]))
}

df_source<- readRDS(here("./data/master_normalized_data_challenge2_train_Aug25.RDS"))

metaDf <- df_source[["subject_specimen"]]
metaDf["age_at_boost"] <- as.numeric(round(difftime(metaDf$date_of_boost, metaDf$year_of_birth,units="weeks")/52, 2))

normalizedData <- list()

normalizedData[["abtiter"]] <- as.data.frame(df_source[["abtiter_wide"]]$batchCorrected_data)
normalizedData[["cytof"]] <- as.data.frame(df_source[["pbmc_cell_frequency"]]$batchCorrected_data)
normalizedData[["rnaseq"]] <- as.data.frame(df_source[["pbmc_gene_expression"]]$batchCorrected_data)
normalizedData[["olink"]] <- as.data.frame(df_source[["plasma_cytokine_concentrations"]]$batchCorrected_data)

int_cols <- Reduce(intersect, lapply(normalizedData[c("abtiter", "cytof", "olink")], colnames))
cols <- unique(c(int_cols, colnames(normalizedData[["rnaseq"]])))

normalizedData[["abtiter"]] <- add_cols(normalizedData[["abtiter"]],  cols)
normalizedData[["cytof"]] <- add_cols(normalizedData[["cytof"]],  cols)
normalizedData[["rnaseq"]] <- add_cols(normalizedData[["rnaseq"]],  cols)
normalizedData[["olink"]] <- add_cols(normalizedData[["olink"]],  cols)

normalizedData[["abtiter"]] <- normalizedData$abtiter[, !duplicated(cols)]
normalizedData[["cytof"]] <- normalizedData$cytof[, !duplicated(cols)]
normalizedData[["rnaseq"]] <- normalizedData$rnaseq[, !duplicated(cols)]

#
MOFAobject <- create_mofa(normalizedData)

## Creating MOFA object from a list of matrices (features as rows, sample as columns)...

Plot multiomic missing values

plot_data_overview(MOFAobject)

metaDf1 <- data.frame(metaDf[metaDf$specimen_id %in% cols, ])
colnames(metaDf1)[colnames(metaDf1)=="specimen_id"] <- "sample"
rownames(metaDf1) <- metaDf1$sample
metaDf1$sample <- as.character(metaDf1$sample)
metaDf1 <- metaDf1[cols,]
samples_metadata(MOFAobject) <- metaDf1

Setting data Options

knitr::opts_chunk$set(warning = FALSE, message = FALSE)

data_opts <- get_default_data_options(MOFAobject)
data_opts

## $scale_views
## [1] FALSE
## 
## $scale_groups
## [1] FALSE
## 
## $center_groups
## [1] TRUE
## 
## $use_float32
## [1] TRUE
## 
## $views
## [1] "abtiter" "cytof"   "rnaseq"  "olink"  
## 
## $groups
## [1] "group1"

Setting model Options

knitr::opts_chunk$set(warning = FALSE, message = FALSE)
model_opts <- get_default_model_options(MOFAobject)
model_opts$num_factors <- 15

model_opts

## $likelihoods
##    abtiter      cytof     rnaseq      olink 
## "gaussian" "gaussian" "gaussian" "gaussian" 
## 
## $num_factors
## [1] 15
## 
## $spikeslab_factors
## [1] FALSE
## 
## $spikeslab_weights
## [1] FALSE
## 
## $ard_factors
## [1] FALSE
## 
## $ard_weights
## [1] TRUE

Setting training Options

knitr::opts_chunk$set(warning = FALSE, message = FALSE)
train_opts <- get_default_training_options(MOFAobject)
train_opts$convergence_mode <- "medium"
train_opts$seed <- 42

train_opts

## $maxiter
## [1] 1000
## 
## $convergence_mode
## [1] "medium"
## 
## $drop_factor_threshold
## [1] -1
## 
## $verbose
## [1] FALSE
## 
## $startELBO
## [1] 1
## 
## $freqELBO
## [1] 5
## 
## $stochastic
## [1] FALSE
## 
## $gpu_mode
## [1] FALSE
## 
## $seed
## [1] 42
## 
## $outfile
## NULL
## 
## $weight_views
## [1] FALSE
## 
## $save_interrupted
## [1] FALSE

Training Model

MOFAobject <- prepare_mofa(MOFAobject,
  data_options = data_opts,
  model_options = model_opts,
  training_options = train_opts
)
MOFAobject <- run_mofa(MOFAobject, outfile=".../MOFA2_2ndChallenge_F40.hdf5", use_basilisk = TRUE)

MOFAobject

## Trained MOFA with the following characteristics: 
##  Number of views: 4 
##  Views names: abtiter cytof rnaseq olink 
##  Number of features (per view): 27 20 10269 30 
##  Number of groups: 1 
##  Groups names: group1 
##  Number of samples (per group): 370 
##  Number of factors: 15

Impute Data

imputed_data <- impute(MOFAobject, views = "all")

Add meta data to Mofa and Imputed objects

metaDf1 <- data.frame(metaDf[metaDf$specimen_id %in% cols, ])
colnames(metaDf1)[colnames(metaDf1)=="specimen_id"] <- "sample"
rownames(metaDf1) <- metaDf1$sample
metaDf1$sample <- as.character(metaDf1$sample)
metaDf1 <- metaDf1[cols,]

samples_metadata(MOFAobject) <- metaDf1
samples_metadata(imputed_data) <- metaDf1

Mofa object

MOFAobject

## Trained MOFA with the following characteristics: 
##  Number of views: 4 
##  Views names: abtiter cytof rnaseq olink 
##  Number of features (per view): 27 20 10269 30 
##  Number of groups: 1 
##  Groups names: group1 
##  Number of samples (per group): 370 
##  Number of factors: 15

slotNames(MOFAobject)

##  [1] "data"               "covariates"         "covariates_warped" 
##  [4] "intercepts"         "imputed_data"       "interpolated_Z"    
##  [7] "samples_metadata"   "features_metadata"  "expectations"      
## [10] "training_stats"     "data_options"       "model_options"     
## [13] "training_options"   "stochastic_options" "mefisto_options"   
## [16] "dimensions"         "on_disk"            "dim_red"           
## [19] "cache"              "status"

Imputed data

imputed_data

## Trained MOFA with the following characteristics: 
##  Number of views: 4 
##  Views names: abtiter cytof rnaseq olink 
##  Number of features (per view): 27 20 10269 30 
##  Number of groups: 1 
##  Groups names: group1 
##  Number of samples (per group): 370 
##  Number of factors: 15

slotNames(imputed_data)

##  [1] "data"               "covariates"         "covariates_warped" 
##  [4] "intercepts"         "imputed_data"       "interpolated_Z"    
##  [7] "samples_metadata"   "features_metadata"  "expectations"      
## [10] "training_stats"     "data_options"       "model_options"     
## [13] "training_options"   "stochastic_options" "mefisto_options"   
## [16] "dimensions"         "on_disk"            "dim_red"           
## [19] "cache"              "status"

Results for Actual Data

plot_object = MOFAobject

plot_factor_cor(plot_object)

plot_factor(plot_object,
  factors = 1,
  color_by = "Factor1"
)

plot_variance_explained(plot_object, max_r2=1)

plot_variance_explained(plot_object, plot_total = T)[[2]]

correlate_factors_with_covariates(plot_object,
  covariates = c("timepoint", "infancy_vac", "biological_sex", "dataset", "ethnicity", "race"),
  plot="log_pval"
)

plot_weights(plot_object,
 view = "cytof",
 factor = 12,
 nfeatures = 10,     # Top number of features to highlight
 scale = T           # Scale weights from -1 to 1
)

Results for Actual Data

plot_data_heatmap(plot_object,
  view = "cytof",
  factor = 12,
  features = 25,
  cluster_rows = FALSE, cluster_cols = FALSE,
  show_rownames = TRUE, show_colnames = FALSE,
  scale = "row"
)

plot_factor(plot_object,
  factors = 1,
  color_by = "infancy_vac",
  dodge = TRUE,
  add_violin = TRUE
)

plot_factor(plot_object,
  factors = 13,
  color_by = "infancy_vac",
  dodge = TRUE,
  add_violin = TRUE
)

Results for Imputed Data

plot_object = imputed_data

plot_factor_cor(plot_object)

plot_factor(plot_object,
  factors = 1,
  color_by = "Factor1"
)

plot_variance_explained(plot_object, max_r2=1)

plot_variance_explained(plot_object, plot_total = T)[[2]]

correlate_factors_with_covariates(plot_object,
  covariates = c("timepoint", "infancy_vac", "biological_sex", "dataset", "ethnicity", "race"),
  plot="log_pval"
)

plot_weights(plot_object,
 view = "cytof",
 factor = 12,
 nfeatures = 10,     # Top number of features to highlight
 scale = T           # Scale weights from -1 to 1
)

plot_object = imputed_data
plot_data_heatmap(plot_object,
  view = "cytof",
  factor = 12,
  features = 25,
  cluster_rows = FALSE, cluster_cols = FALSE,
  show_rownames = TRUE, show_colnames = FALSE,
  scale = "row"
)

plot_factor(plot_object,
  factors = 1,
  color_by = "infancy_vac",
  dodge = TRUE,
  add_violin = TRUE
)

plot_factor(plot_object,
  factors = 13,
  color_by = "infancy_vac",
  dodge = TRUE,
  add_violin = TRUE
)

results <- imputed_data@imputed_data

saveRDS(results, file = here("./results/imputedData.RDS"))

knitr::kable(MOFAobject@data$abtiter$group1[1:10,], "html", align = "lccrr", booktabs=TRUE, border_left = T, 
             border_right = T, caption = "Ab-titer Before Imputation")  %>% 
  kable_styling("striped", full_width = T) %>% 
  scroll_box(width = "100%", height = "400px")

Ab-titer Before Imputation
	1	102	103	104	105	106	114	115	116	117	118	131	132	133	134	135	138	139	140	141	142	146	147	148	149	150	153	154	155	156	157	160	161	162	163	164	167	168	169	170	171	174	175	176	177	178	181	182	183	184	185	19	191	192	193	194	195	2	20	201	202	203	204	205	208	209	21	210	211	212	22	223	224	225	226	227	23	241	242	243	244	245	248	249	250	251	252	255	256	257	258	259	27	274	275	276	277	278	28	281	282	283	284	285	29	293	294	295	296	297	3	30	31	324	325	326	327	328	332	333	334	335	336	342	343	344	345	346	349	350	351	352	353	355	356	357	358	359	360	361	362	363	364	369	37	370	371	372	373	38	385	386	387	388	389	39	397	398	399	4	40	400	401	405	406	407	408	409	41	45	46	468	469	47	470	471	472	475	476	477	478	479	48	483	484	485	486	487	49	490	491	492	493	494	498	499	5	500	501	502	506	507	508	509	510	513	514	515	516	517	521	522	523	524	525	529	530	531	532	533	537	538	539	540	541	546	547	548	549	550	554	555	556	557	558	562	563	564	565	566	569	570	571	572	573	577	578	579	580	581	585	586	587	588	589	593	594	595	596	597	601	602	603	604	605	608	609	610	611	612	616	617	618	619	620	623	624	625	626	627	630	631	632	633	634	636	637	638	639	640	643	644	645	646	647	650	651	652	653	654	657	658	659	660	661	664	665	666	667	668	669	670	671	672	673	674	675	676	677	678	681	682	683	684	685	688	689	690	691	692	695	696	697	698	699	70	702	703	704	705	706	709	71	710	711	712	713	716	717	718	719	72	720	723	724	725	726	727	73	74	77	78	79	80	81	87	88	89	90	91
IgG_PT	0.2286072	-1.8671452	-1.4501789	-1.1901960	-1.2697170	-0.3279574	-3.1105289	-3.2181387	-2.3371587	-2.5470605	1.9200621	6.2884302	4.3913341	4.1997566	5.2109346	5.5448370	-1.2455463	-1.9231960	-2.2742720	6.6989202	6.2869015	-0.0228052	0.1423607	0.6658998	5.5433569	5.6128092	1.3176870	1.5664721	-2.0884161	2.5118661	3.6569157	2.2753177	-2.8923512	-3.2429376	-2.0468955	-1.5303488	-0.0199063	-3.0967369	-3.3001652	3.8638716	1.3637309	-3.0920167	-3.0687993	-3.1234784	0.8306389	3.6012812	-3.2043469	NA	-3.2456307	-3.2524414	-2.1522374	-2.3385165	-2.7419217	NA	-3.0941114	-2.9178779	-2.1804433	NA	-2.7115178	-2.7675679	-3.2031112	-2.7972715	-2.4008918	-0.9803596	-2.7177968	-3.2031112	-2.9024177	-2.9147718	-3.3759651	-1.0751638	2.8408790	-2.4363956	-2.6429234	-2.4297507	-1.5422397	0.5743141	3.4411798	-3.2862308	-3.2469838	-3.3191018	-2.4370961	-1.6556993	-1.8044015	-1.9491197	-1.8577056	4.3268204	11.0455389	-2.8634224	NA	NA	-2.7939916	-2.6959062	-1.4146631	-2.1538534	-1.6742907	-1.2004201	0.4876294	0.6935158	NA	-2.3764157	-2.8958445	-2.8279164	-1.9863790	-1.2107742	-1.8222170	-2.7170110	-2.8780313	-2.9362183	1.3774099	3.0154672	-1.2116141	-2.0226612	4.2723751	-2.2686095	-2.3493979	-2.3517830	4.3445482	5.2126427	-2.4280045	NA	-2.6255436	-2.6528065	-1.9997973	-2.5260115	-2.6247911	-2.5383298	8.8255177	12.1668940	-3.304162	-3.2736278	-3.3759651	-2.9929132	-1.3644943	6.1642675	6.9529400	5.7701063	9.2760868	7.2582760	1.7613034	1.6009302	2.1012602	8.5239210	11.4787149	-3.3759651	0.2879243	-3.3759651	-3.3759651	-3.2149711	-3.3759651	-0.3357458	-2.9943309	-3.0338178	-3.2200494	-2.5267344	-0.6024125	-1.2287071	-0.5625732	-0.7877033	-3.3759651	-0.2444699	2.4256587	0.0327477	2.4238706	13.2098522	5.2144222	2.5647779	3.1423616	8.2141352	1.7745547	-3.1969750	NA	-2.7588196	-2.7728333	-3.2105696	-2.6397026	-1.7171280	-0.9720616	-2.6448290	-1.2411144	-1.3532248	4.1495233	10.6542568	-3.2343001	-1.208416	0.3120804	0.8446045	10.4533920	14.0946426	5.4704180	-0.5123975	0.9216805	0.6414046	0.3284299	1.4051561	-3.0297530	-3.0297530	7.1670647	-2.8592520	0.9011149	13.3570366	-2.2262957	-2.4318314	-2.4131463	13.4621410	15.4287434	-3.1470010	-3.1913781	-3.2100632	-0.3605926	16.0729103	-2.6775637	-2.6892419	-2.6518717	4.9669580	10.8130436	-2.6495116	-2.6354978	-2.6728678	2.9092913	6.9335842	-3.4062448	-3.2077162	-3.2824564	-3.3385115	-1.9324614	3.0330911	5.1515093	3.1031599	2.9443374	4.7544518	-0.3858180	-1.1448984	-0.4535515	5.1916695	12.4087715	-0.9795597	-0.7740240	-0.5895090	5.3616800	8.7973938	-3.3548968	-3.3081841	-3.2614715	-1.4677064	-0.2088013	-3.6743872	-3.7210999	-3.7024148	-3.3240426	-2.5392704	7.3568001	6.5183086	6.6911449	6.7425289	7.8379402	-3.1652195	-2.9596839	-3.2306173	-1.7194637	0.9197998	-2.7658267	-2.6724014	-2.8195462	0.8123608	3.956121	0.4036252	-0.1615975	0.3569126	0.7633123	5.7101803	-3.4081252	-3.3754263	-3.4268103	-2.5649624	-1.4905717	-1.1565764	-1.0911789	-1.0141029	-0.7151423	1.015561	NA	NA	NA	NA	NA	-2.3365369	-2.4369693	-2.3855853	-0.7179444	0.2653565	-3.5860884	-3.2544289	-3.2824564	-2.3855739	0.6250553	-3.5389206	-3.5062218	-3.5108931	-2.8055325	-2.2356381	-3.5650792	-3.5931067	-0.3208871	0.5946808	1.9353333	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	-3.761297	-3.751954	-3.763632	-3.1843958	-2.5607820	-3.5323803	-3.5510652	-3.5277090	-3.0932815	-1.7386153	-2.8620787	-3.0279083	-2.8153658	-1.2855272	0.7418008	-3.6230032	-3.6043184	-3.5762906	-2.1281991	-0.2830503	-3.1897013	-1.7217994	-1.7965395	-1.7498269	1.6648664	2.2160754	1.7839837	-3.2162356	1.3939333	1.0389171	2.8186684	5.4719458	0.3143804	0.8048630	0.7184443	2.3720717	-3.0642281	6.2655697	-3.0764656	-2.9923828	-3.0764656	-2.5019002	-0.2059746	-2.5216775	-2.4819136	-3.3759651	NA	-3.3759651	-3.1586101	-3.2018783	-1.0448363	-1.4895899	-1.5373070	24.8775043	18.5586281
IgG_PRN	0.1738322	-0.9681737	-0.7938274	-1.5947855	9.0814171	10.3917313	-1.0831721	-1.2663052	-0.1815922	2.5808744	12.8597584	-1.6000944	-1.6183333	-1.6171044	-1.5888475	-1.5700758	-0.3392340	-0.9096758	-1.1963954	-1.3722241	-1.4701777	0.1597440	-1.5843766	-1.5767007	-1.5080463	-1.4806919	-1.5156047	-1.5099031	-0.0108745	-1.5785159	-1.5670462	-0.1460013	9.6972046	3.3309345	7.8797402	9.4235554	-0.7403853	-0.3363878	-1.2771419	-1.4963048	-1.5157592	-1.6397417	-1.6121037	-1.6836741	-1.4601562	26.6672688	-1.0434580	NA	-1.1338631	-1.1720755	1.6275346	4.2445378	-1.3263733	NA	-1.6014882	-1.4619166	3.1292343	NA	2.3413334	-0.9759914	-1.6193471	-1.0463680	2.3562670	-1.5808481	-1.2797123	-1.7023462	1.0390458	-1.4357263	-1.4992273	-1.5327127	6.5208983	3.1951404	2.1687603	3.3699713	4.4557972	-1.5101753	4.5864801	0.5568385	0.8062139	0.0913894	1.7246742	2.2625904	-0.7318426	-0.8028685	-0.8415129	-1.4338789	-1.3012469	-1.7765627	NA	NA	-1.7604377	-1.7490320	2.6467900	-0.8315591	-0.2790837	0.5550735	-1.5567549	4.2862310	NA	1.3367503	-0.3211818	0.0435722	1.5920389	1.7721052	1.3617444	-1.5374529	-1.6166992	-1.6620166	-1.5358528	-1.4636240	-0.8191681	0.4587932	4.3402071	2.0242109	1.5799005	1.5772588	-1.4836296	-1.4568031	-0.7317934	NA	-0.9351045	-0.9740496	6.1874518	-1.3941007	-1.4479740	-1.4169009	-1.4119363	-1.3409233	-1.811040	-1.7994505	-1.8684022	-0.7933410	7.9425826	-1.6608535	-1.6499286	-1.6650485	-1.4750544	-1.4906857	-1.5541267	-1.5484018	-1.5480433	-1.4704370	-1.3969444	-1.0822375	2.3226595	-1.4807143	-1.8845582	2.1890731	-1.4505448	1.7719436	-1.7230691	-1.7377948	-1.8184482	0.0036395	-1.4193838	0.8211677	-0.3506563	-0.4230908	-1.5989388	-0.1221540	2.3404298	-1.5589350	-1.4871354	-1.6128826	-1.7349956	-1.7788384	-1.6134267	-1.5413282	2.1567163	-1.8510678	NA	-6.7225909	-6.7171974	-1.8516042	-6.7167826	-2.7019672	1.6789250	-4.7169113	-3.2355926	-2.7503018	1.5881326	5.0793486	-1.8549962	-6.832054	-6.6214247	-6.5525517	-1.2605468	2.3844576	-0.1051459	-4.0772791	-1.7562099	-1.8579978	-3.0639637	-0.2841570	-5.1524844	-5.1600909	4.2504387	-5.1963253	4.6827760	5.3728871	-1.1102859	-1.3122022	-1.1311690	5.1749816	5.4016533	-6.1257930	-6.0357604	-6.1884422	-1.1771837	3.7943830	2.8507710	2.5076513	2.7199402	4.5156121	4.0650349	-2.4618418	-2.3388941	-2.4359798	4.9989657	5.1104345	0.4103799	2.4939899	2.1360726	0.4153585	4.7670698	-4.1988440	-2.5962369	-3.3225825	6.2429948	6.1367812	4.6483760	4.8706222	4.7060466	5.2047524	5.1141667	-1.1665338	-1.0536820	-0.9784474	2.8398452	4.2379084	0.0716558	0.0144000	0.2228162	4.7482309	5.4615765	1.6699357	0.9541008	1.2008259	6.5446935	6.5904698	-6.8320537	-6.8320537	-6.8320537	-0.1246300	2.4319625	-3.2706888	-3.2037520	-3.5767441	-2.4059062	-0.7088411	-6.4363494	-6.3179655	-6.3183804	-1.2444725	4.374610	-6.7336183	-6.7078948	-6.7493844	-6.1047735	-2.0748837	-0.1301987	-0.6240638	-0.6370640	3.6867108	3.9189148	-2.8965905	-2.8674095	-3.0084741	-0.0781984	4.431036	NA	NA	NA	NA	NA	3.7007546	3.3677311	3.5298171	4.3969507	4.1762261	-5.8310471	-3.9302676	-3.7963943	1.2192898	6.1865687	-3.9415398	-3.9715505	-3.3348227	5.3601637	5.6273570	-6.4094439	-6.3636670	3.5923281	2.6141405	4.3963976	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	-6.757403	-6.595040	-6.545114	3.4619136	4.6149111	0.2374749	0.3348374	0.4859982	4.2416415	5.7730241	-4.5874939	-5.0718164	-4.6926012	3.3717427	5.0992336	-3.4468083	-3.5082130	-3.7311506	0.8725412	4.7753344	-1.7984945	0.0477269	-0.0140927	-0.3372971	2.8858957	3.2702279	-2.2212772	-1.8028789	-2.3670442	-2.4353638	-0.3525833	3.9389682	-3.6073699	-3.2461336	-3.3274531	2.7015462	-0.1097751	3.1492200	-3.9724822	-3.4844255	-3.7679381	-0.0181034	3.8228703	1.3095279	1.3415613	-1.8699592	NA	-1.8643135	6.7920518	6.0107684	4.5958686	3.2968287	2.9997959	5.9004855	4.3414626
IgG_FHA	28.1716576	-2.4690032	1.2192688	-1.3238370	66.5263367	17.0829258	-2.3709695	-2.6608338	-2.9473746	-2.4582436	-3.4231730	-1.2233400	-1.3374193	-1.3380346	-1.2494659	-1.1499288	6.2256665	1.5930734	-2.7562797	-0.5703006	-0.6054721	-2.5153587	-1.7862821	-1.7412896	-1.3525579	-1.4144533	-1.7270484	-1.7311876	7.7536769	-1.2578030	-1.1435692	9.7472324	-2.6742270	-3.1815734	12.6009922	-3.4231730	-0.3287888	-3.0182199	-3.2500668	-1.2332358	-1.3337688	-1.4317210	-1.5519383	-1.7419741	-0.6054721	59.0285034	-3.0140111	NA	-3.0336568	-3.0425212	-1.5426140	-2.4818163	-3.2499757	NA	-3.3551948	-3.3073027	-2.2528117	NA	-2.8036473	-2.5937035	-3.1467984	-2.6142209	-1.2842054	-1.5359819	-1.4510622	-2.7749243	-2.9382591	-1.8684065	-1.3929605	-1.4204111	-3.4231730	1.1327028	0.3308849	2.1651030	7.7871976	-1.1092241	7.2550330	-3.1979704	-3.1591272	-3.2365913	-1.1718287	2.2250843	-2.8084872	-2.8814111	-2.8542719	-1.3805285	-0.3930731	-2.9523709	NA	NA	-2.8746164	-2.8518114	-2.5266335	-1.2829628	-0.2844052	3.2556205	-1.3493223	-3.4231730	NA	-0.7024708	-2.1785424	-2.0142820	-1.2524590	-0.3287888	-2.7391324	-2.7909214	-2.9045470	-2.9540575	-1.3275542	-0.7519817	0.6272984	-2.8450425	-0.7752333	-2.7332089	-2.7885306	-2.7526243	-1.4906681	-1.0670519	-2.5493734	NA	-2.7191806	-2.7539959	0.5278273	-3.0896959	-3.1249018	-3.0931931	-1.2760546	-0.8164163	-3.253939	-3.2416406	-3.3684063	0.3994660	-3.4231730	-1.5740309	-1.5376809	-1.5809906	-1.1964498	-1.1840000	-1.6783345	-1.6474540	-1.6621492	-1.1621015	-0.7162952	-3.1327858	-3.4231730	-3.3081088	-3.4231730	-1.5219944	-1.1386273	6.2943883	-3.0097747	-3.0248628	-3.2170763	-2.2034242	-1.0093827	0.8393555	-3.4231730	51.4704285	-1.3178914	6.1140351	-3.4231730	-1.1939249	-0.6843572	-0.9501338	-0.7108736	-1.4266994	-1.4988372	-0.6960182	-3.4231730	-3.1489081	NA	3.7088056	3.7429652	-3.1452661	3.7455926	8.0891247	14.2339230	-1.6297033	4.4875045	4.5873551	19.3036022	33.0055695	-3.1438670	-5.341282	-4.2258377	-4.3664179	15.7404861	30.6761436	5.8789334	-2.3509977	0.4317012	0.6668773	1.4709430	20.7291107	1.7222891	2.2846098	-3.4231730	3.6759591	7.1418509	15.8630772	5.7859759	1.5738263	3.6615071	9.3504047	14.2168446	-5.1750236	-8.0050201	-3.9347649	-1.3202367	3.6250319	-7.3430147	-7.2300248	-1.0550089	2.0640311	4.9242463	-6.2063828	-5.3090343	-6.9828577	1.2522488	5.2213387	2.0358915	9.6364174	5.8985610	3.9278111	19.8921986	19.4822826	35.0801125	29.1639214	37.5580025	51.4268227	-8.4493494	-8.4138756	-7.7858634	-8.2851200	-7.4285007	-7.8357019	-2.1980436	-0.7633376	-2.5514648	-0.5071402	-8.0748196	-7.2576151	-6.1723890	0.1826220	0.6109319	-0.1814551	-2.4123437	-3.9285073	2.9586062	25.0191803	17.2360325	12.0831795	7.5714746	12.9095802	15.8643913	-8.6508503	-8.5496855	-8.6377125	-8.6193180	-8.6377125	-8.6219463	-8.6101217	-8.6272011	-8.5247231	-8.522095	-8.5268650	-8.5978127	-8.5216103	-8.4270134	-8.3902264	-8.5864725	-8.4853077	-8.5890999	-8.5444298	-8.4393234	-8.6403399	-8.5890999	-8.5628242	-8.6061802	-8.532606	NA	NA	NA	NA	NA	-7.5398221	-8.4793139	-4.4327078	-1.8681052	-0.8998098	-4.0826297	2.5640526	2.9476914	16.1819344	60.5553360	1.7827258	1.5317836	3.6575656	14.6556644	18.0361576	-8.0102758	-8.5803776	-4.5312452	-6.0736852	-3.6352110	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	-8.669245	-8.669245	-8.669245	-8.6692448	-8.4545174	-7.9130516	-8.5923033	-8.6146393	0.5204434	3.5659089	-7.3325043	-8.6542206	-8.2666397	-8.3297033	2.1113291	-8.6692448	-8.6692448	-8.6692448	-8.6214609	-8.5715351	-3.1520178	-8.6004400	-8.6385412	-8.5781050	-8.5820465	-8.5360622	-8.6377125	-3.1897321	-8.6088076	-8.6390257	-8.5536270	-8.5825310	-8.3651772	-7.7608137	-2.3609591	-2.7170079	-2.9020247	1.2087259	-8.5334339	-8.6267166	-8.5032158	-8.5413170	-8.2969446	1.9252558	2.0712256	-3.4043312	NA	-3.4024038	-1.1959963	-1.4209409	0.7351441	-0.6770272	-0.8449941	14.6441936	29.9746552
IgG1_PT	4.5489502	-5.2782645	-6.3563328	-4.5102205	-1.6850395	27.4568558	-13.5755796	-13.5382710	-13.3978901	-13.0963564	-4.9428029	36.3497734	30.0857849	23.9210663	4.0720243	41.7434578	-5.9762497	-7.0830765	-7.7454815	3.6112766	35.2881165	0.1571569	7.4935608	0.3764420	2.5801153	28.9595108	-11.6743917	-11.6872931	-11.6341686	10.7250271	14.0752602	-13.3287773	-13.2863359	-13.2674732	-7.7665448	-7.3492002	-13.4584608	-13.4592466	-13.4026575	18.3650246	22.5243187	-13.4733944	-13.4199486	-13.5016890	1.7435608	19.1847801	-13.5150499	NA	-13.5433445	-13.5457020	-9.9141502	-10.1543427	-12.0020790	NA	-12.4461460	-12.6599264	-12.1238356	NA	-9.1255331	-11.5006371	-11.6153870	-11.8543186	0.2085962	18.8719673	-13.1299305	-13.1558666	-11.0567617	-13.2218876	-6.7726870	5.1558027	12.5384407	-12.8233337	-12.6769152	-12.4656057	-10.3192406	-1.7745414	28.8864784	-13.6269732	-13.6452751	-13.6286373	-9.7321863	-7.6615758	-9.5929699	-8.1662188	-9.1630573	24.2385178	38.9098740	-11.7251930	NA	NA	-10.6836233	-13.1218691	-4.0236173	-6.3684297	-6.3276653	-7.4836712	-0.1994696	9.3974915	NA	-10.8516722	-11.9847536	-11.7229052	-8.8187790	-4.3703423	-2.7336035	-12.0268250	-11.9082222	-12.3105669	7.3697090	14.3508148	6.9115887	-2.5339084	22.1912155	-10.5252991	-11.2883186	-8.4601011	19.3002644	34.9413834	-13.2873049	NA	-13.5251188	-12.8923950	-11.8550663	-10.3991804	-12.0659571	-10.1059532	42.2712593	45.8483086	-13.624674	-13.6854000	-13.6672382	-13.5584602	-13.5206251	24.9314766	6.8681164	35.0162659	38.1708183	32.7957840	17.0393810	18.0800533	19.0645695	43.7357559	40.5632668	-13.6839104	4.8514414	-13.6853323	-13.6839104	-13.6273937	-13.4180841	0.9763451	-13.4429350	-13.6085615	-13.5175743	-12.6801682	-4.3636246	1.7641716	-10.7978935	-11.5648918	-9.8027143	2.6160355	20.3257084	-5.7229018	-7.5147505	7.6740417	10.1833115	10.6425152	20.5556335	28.2532806	18.5360355	-13.4876499	NA	-8.1667280	-6.6261358	-13.5280952	-2.7130313	-7.4272437	-9.0294600	-9.5865021	-10.1390896	-10.1390896	13.5223827	48.4938278	-13.5955029	-7.922662	-9.8329964	-9.4632540	59.6477203	77.4569626	-11.5463104	-4.7798538	-9.0935125	-8.3540277	-2.2532821	1.5365753	-8.6597176	-5.3936620	34.5301857	44.7680244	2.1244287	-9.0910835	-8.3824110	21.6899509	41.6560287	-3.3292680	-8.5980940	-8.6178141	-8.2480717	-8.7410612	-2.6403160	87.4227142	-4.7349362	-3.5948982	-3.9030166	24.0125160	67.9810181	-10.1390896	-9.9391050	-10.1390896	6.8805447	28.6645203	-10.1390896	-10.1390896	-10.1390896	-10.1390896	-9.6481256	-10.0794916	-10.1390896	-10.1390896	-7.1831779	-5.7658329	-3.1938462	-2.4235501	12.7050667	49.3095398	54.4551163	-0.4520893	0.4414539	-0.8218317	25.3066139	48.4154968	-10.1390896	-10.1390896	-10.0653858	-3.1635323	2.1977291	-10.1386862	-9.5840731	-7.7045503	-9.8305674	-10.1386862	0.4297771	1.1076374	3.7266445	-2.5589719	-0.5253897	-8.8019257	-9.1100435	-9.0484200	9.4386883	41.4213829	-9.8495283	-9.1100435	-9.9111519	5.8645134	32.331890	1.6128016	1.4279308	3.7388191	20.5004635	41.2368355	-10.1390896	-10.1390896	-10.1390896	-7.6618872	-1.0373402	-9.4797859	-9.5414095	-9.2949152	-7.4770160	-1.684389	NA	NA	NA	NA	NA	-9.9119120	-10.0967827	-10.0351591	-3.3181763	1.4268475	-10.1390896	-10.1390896	-10.1390896	-8.7237701	2.4917421	-9.7689438	-8.2283516	-2.6822195	-9.4300137	-9.0294600	-10.1390896	-10.1390896	-3.9960370	-1.1613474	4.5080328	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	-10.139090	-10.139090	-10.139090	-10.1390896	-8.4136257	-10.0623522	-9.6037931	-9.9391050	-6.1220541	-1.9008317	-9.5723963	-9.9421387	-9.9542179	-6.8609538	-0.7293959	-10.1390896	-10.1390896	-8.5520306	-3.7484598	-1.6532540	-13.6854000	-7.5075049	-7.7848115	0.4419518	9.8703766	5.8648367	1.3384113	-13.6854000	-0.5719233	0.2908077	16.1248589	38.9256248	-0.5753374	1.2425623	1.2117500	8.4833450	-13.6854000	30.6370621	-10.1390896	-10.1390896	-10.0926228	-6.3366547	-3.5635886	-13.5382061	-12.4532080	-13.6854000	NA	-13.6854000	-13.6854000	-13.6268787	-9.5959778	-8.6461582	-6.9540501	56.2190247	52.1034012
IgG1_PRN	0.6040584	-0.1978105	-0.4134544	-0.4735459	0.8017174	1.5388781	-1.6871194	-1.6671293	-1.6440828	-1.4979178	-0.4089648	-0.1328797	-0.3395532	-0.5439583	-0.7448503	0.8921920	-0.1633550	-0.2664542	-0.5073088	0.2375665	1.3716379	-0.1627313	0.2434068	-0.3184346	-0.1086131	0.9501547	-0.8034200	-0.6806430	-0.6245171	0.2278665	0.2224904	1.1315607	1.5548013	1.2236472	1.6620077	1.3266946	-0.2008393	-0.2246629	-0.1212885	0.9130489	0.9309908	-1.5079899	-1.4697295	-1.5193373	0.7537097	0.7681168	-0.1917495	NA	-0.2958665	-0.3034710	0.3712469	1.6845137	-1.2149177	NA	-1.3068556	-1.3392937	0.3078221	NA	1.7807590	-0.4698205	-0.4979514	-0.7329349	-0.5094184	0.1205122	-1.2774770	-1.3127669	1.6445183	-1.3403333	0.4492387	0.8840119	1.8465756	0.9402035	1.0958816	1.1210369	1.2386872	1.4782990	2.1048827	0.4279770	0.2293704	0.3936712	0.9918417	0.9283201	-1.5858178	-1.5380505	-1.5777037	1.3722392	1.3461229	-1.7023513	NA	NA	-1.6919605	-1.7403773	1.0599436	0.6561433	0.6231405	0.3468620	0.8401464	1.2691768	NA	0.7522362	0.5535055	0.4316796	0.4764682	0.6940647	1.1131855	-1.4139265	-1.3719144	-1.4170384	0.6672772	0.9826888	0.6891369	1.1258241	1.4476763	0.8363398	0.6365818	1.0971590	1.4339291	1.7964171	-0.4379482	NA	-0.8224090	-0.1168195	1.2112807	-0.9229801	-1.2242576	-0.9064364	1.3887197	1.4095949	-1.742105	-1.7496883	-1.7544377	-0.3121858	0.5009533	-1.5055299	-1.5756340	-1.3643367	1.2043625	1.0847062	0.2076728	0.2453396	0.2479219	1.3619283	1.3736607	-1.2249581	1.2448829	-1.2830020	-1.2030933	0.9659494	1.3531443	1.0450972	-1.6397704	-1.7106414	-1.6730587	-0.1696870	1.1196755	1.1183690	-0.4640992	-0.6372488	-0.2578578	0.4671458	1.4535955	0.9227556	1.2089747	-1.7336569	-1.7157216	-1.7060101	-0.7620926	0.1079565	1.4831923	-1.7492149	NA	-1.6232650	-1.1995394	-1.7507507	-0.0519038	-1.3275919	-1.6738120	-0.8146209	-1.1281213	-1.2005720	0.4810141	2.1278152	-1.7570540	-1.639462	-1.6743555	-1.6668550	0.1099554	0.7432066	-1.5153849	-0.3117592	-0.9475650	-0.7313541	-0.0972875	0.3811158	-1.4549922	-0.6661321	1.4410530	0.6536895	-0.4424206	-1.5214100	-0.5553091	0.1834931	0.7933189	-0.1162562	-0.6195527	-1.6499282	-1.6409059	-1.6521024	-0.4510392	0.8757395	1.0256087	1.0183254	0.8951646	1.4235717	1.6734806	-0.5666995	-0.3754359	-0.4363098	1.4368118	1.4865979	0.6049360	-0.0251086	0.2052338	0.8027760	1.2775379	-0.7027651	-1.2980790	-1.1350783	2.4196296	2.6453519	1.3300866	1.3687850	1.3870472	1.4934133	1.7468551	-0.0093558	0.2424011	0.0953798	0.7960273	1.3186728	0.3573006	0.2658811	0.3496913	1.3086721	1.7796293	0.0758768	0.5678138	1.1932384	0.4646543	-0.0129881	-1.6764209	-1.1155660	-0.2167525	-1.3630292	-1.6783776	0.2962092	0.2766424	0.2031047	0.8547813	1.6163024	-1.6147412	-1.5382684	-1.5715317	-0.1583883	1.731854	-1.6633860	-1.6765934	-1.6311010	-1.2307467	-0.7964768	0.0307555	-0.0584899	-0.0667514	0.8676625	1.5046641	-0.3795996	-0.4822155	-0.4296031	0.3345815	1.443301	NA	NA	NA	NA	NA	1.0518931	0.9786271	0.9431897	1.4601287	1.4424099	-1.3989012	-1.3292224	-1.3104711	0.4919389	2.4697962	-1.2222040	-0.1650641	0.8960437	-0.6574901	-1.1202946	-1.6148170	-1.1540236	1.2843009	1.1655425	1.2919101	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	-1.679170	-1.644308	-1.664387	-0.5951806	-0.1942828	0.1113919	0.3571702	0.0982388	1.2467982	1.5750281	-1.1061181	-1.2321596	-1.2618356	0.6506366	1.3011173	-1.0875844	-1.1223695	-0.5081956	0.5100828	0.6527561	-1.7181463	-0.1376259	-0.1433872	0.3528436	0.7957009	0.7498826	-0.8265286	-1.7344005	-0.8914245	-0.8843588	0.2796861	1.6401085	-0.8525676	-0.7541910	-0.7040244	0.6444949	-1.7376002	1.4835216	-0.8001727	-0.6309217	-0.4636272	0.5857404	0.7565678	-0.6026548	0.4650418	-1.7413437	NA	-1.7620775	0.6950563	1.1135772	1.2180132	1.3526865	1.5189046	1.9840239	1.8816971
IgG1_FHA	2.1650176	-0.5073866	0.9602586	0.9013363	0.7951263	2.6512389	-0.7148553	-0.5184762	-0.7494589	-0.7993176	1.6478235	1.2631060	1.0546361	0.8518208	-0.2021405	1.8640510	1.0262190	0.8587190	0.5519689	0.7014374	2.4500346	-1.2442319	-0.7012465	-1.2561872	-0.5567608	0.7613748	-2.3244481	-2.2771554	-2.2888060	0.8189384	0.9182965	-1.2461553	-1.1323349	-1.1051238	2.1340127	1.9675969	-1.6926901	-1.6984044	-1.5884714	1.4865428	1.8228337	0.1936251	0.2565993	0.0839252	1.9118141	1.8587912	-1.3773907	NA	-1.4431639	-1.4330570	0.1347104	-0.6326562	-2.2413056	NA	-2.2903633	-2.3429198	-1.1757785	NA	-0.4441348	-0.9617600	-0.9969013	-1.3106457	0.0764506	1.4793903	-0.3385471	-0.3080318	-0.8871602	-0.3838731	0.2145358	1.4146277	1.6837598	0.6778787	0.8706509	0.8856226	1.0728916	1.7654790	2.1969528	-2.0698106	-2.1515484	-2.0574284	0.6036483	0.7890309	-1.7477955	-1.5710473	-1.7955905	0.7742068	1.8676728	-1.2811608	NA	NA	-0.9089701	-1.8959121	-0.6613407	0.8501760	0.7789587	0.5665878	1.1559504	1.7610987	NA	0.6141881	0.1635773	0.0906904	0.0552726	0.5128199	-0.5271817	-1.8318899	-1.8312087	-1.8881418	0.7203590	1.8898691	2.2984452	-0.4199196	0.5354046	-1.2349010	-1.4124660	-0.8091893	0.3108417	2.3332105	-1.0294999	NA	-1.6071985	-0.6496267	0.5346419	-1.9018600	-2.2247033	-1.9271585	1.4920968	1.9681674	-2.390620	-2.4716613	-2.4961753	0.4979233	0.6556619	-0.5511293	-1.1873314	0.0106310	1.2830476	1.1418043	-0.1012447	-0.0921565	-0.0439075	1.9835066	2.1680789	-2.1062708	1.9244090	-2.1937172	-2.1483870	0.3393458	1.9464158	1.6330947	-1.9817693	-2.2295899	-2.1027241	-0.9564538	1.3854898	1.8491632	0.7154399	0.3701609	0.8624033	1.9808031	2.3040524	1.7739431	1.8630880	-0.3435236	-0.2906936	-0.1972991	0.1887494	1.5987254	2.3133969	-1.6593666	NA	-0.6833845	-0.5259489	-1.6793563	0.8639785	-0.2960649	-0.6839070	-0.9608921	-1.0268967	-0.9929366	-0.7506876	-0.5477976	-1.8934745	-1.052149	-1.0378685	-0.9410385	-0.5756623	-0.6306951	-0.2012510	-0.8172147	-1.0394359	-0.9338982	-0.8480400	-0.6352232	-0.8352473	-0.6765926	2.9862642	0.2162977	-0.3953329	-0.9202347	-0.7460803	-0.5849873	0.2060226	0.4472266	-0.6974910	0.7951545	0.9569441	0.6917068	1.5790240	3.7979274	-0.4519851	-0.4199406	-0.3128356	0.1161070	0.4776520	-0.0921628	0.4012169	-0.0056081	2.3757811	4.3597498	-1.0876766	-1.1007383	-1.1162380	-0.9217073	-0.7731535	-1.0082622	-1.0782723	-1.0199306	-0.5817577	-0.4650742	-0.4584544	-0.5939466	-0.3193048	0.1463844	0.5053169	-0.3938174	-0.4072274	-0.4154127	-0.3056953	0.0077829	-0.9559883	-0.9498929	-1.0064931	-0.5049281	-0.2200112	-0.9235437	-0.4130968	0.9059497	-0.6844295	-0.9557623	-0.1104162	0.5224615	1.4313740	-0.3319408	-0.3479630	0.1113303	0.1329254	0.0690107	2.2287011	4.5545349	-0.1058404	0.1071506	-0.0656108	2.5989537	6.624885	-0.8927957	-0.8649310	-0.9433005	-0.6061374	-0.6353953	0.1580037	0.1179482	0.0667467	1.2431606	3.6266398	0.1127235	-0.0370494	-0.0229429	0.5484582	2.456495	NA	NA	NA	NA	NA	0.3709141	0.2416915	0.0988847	2.3980732	3.3597546	-1.1963471	-1.1963471	-1.1963471	-0.8713767	1.7653230	-0.7405072	-0.1212138	-0.0842930	-0.5621730	-0.3497045	-0.7583040	-0.5724812	0.8280698	1.2921916	1.0264317	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	-1.196347	-1.196347	-1.196347	-1.1963471	-1.0198193	0.1967596	0.5104119	0.2413431	2.4553699	4.5342526	-1.1954508	-1.1398954	-1.1963471	-0.8157939	-0.4495469	-1.1733587	-1.1963471	-0.2111548	1.4460996	1.5572103	-2.0387659	0.1058064	-0.0178434	-0.3905340	0.5694057	0.6045851	0.6634341	-2.2090039	0.5286385	0.5397843	2.5846729	4.9629273	-0.8222376	-0.8365183	-0.8427879	-0.6200442	-2.1949463	0.0250242	-0.6350471	-0.7120234	-0.5037345	0.4887723	0.4821543	-0.4533172	1.2266027	-2.6426845	NA	-2.6755946	-2.2294002	0.4259149	0.1151738	0.3617643	0.8783571	2.4155822	3.5894675
IgG1_TT	0.2615502	-0.2353513	0.1466279	0.1843677	0.5641429	0.6953663	-1.2687074	-1.2615327	-1.2467288	-0.3630413	0.4495194	0.0872142	-0.0396972	-0.1238992	-0.2165351	0.3713313	0.3194535	0.2673528	0.1574553	0.3653775	0.7529650	-0.0779227	0.1711683	-0.1313090	0.3344480	0.6583568	-0.6446787	-0.5361797	-0.5238893	-0.0218220	-0.0560675	0.1707152	0.2438167	0.2373384	0.9273441	0.6887044	-0.6396801	-0.6568357	-0.5761761	0.4889148	0.5185474	-0.7684675	-0.7117019	-0.7859231	0.5610566	0.4815568	-0.2110684	NA	-0.2638350	-0.2502384	0.2876931	0.2056671	-0.3632899	NA	-0.4268938	-0.4456491	0.3823332	NA	0.2771745	-0.1293490	-0.1022758	-0.2344424	0.4671930	0.6198019	-0.0776820	-0.0968171	0.1492517	-0.1326882	0.2326161	0.4977126	0.5822273	-0.1691123	-0.1309977	-0.1012205	0.4868871	0.6868454	0.6877887	0.1358256	0.0487738	0.1226621	0.5816299	0.6652027	0.1543695	0.2531884	0.0893461	0.5650262	0.6167666	-0.3678589	NA	NA	-0.2266951	-0.6102981	0.5291293	-0.1104001	-0.0922669	-0.1940876	0.1490703	0.4421091	NA	-0.1526425	-0.2813821	-0.2743973	-0.1425729	-0.0084909	0.5637157	-0.6221525	-0.6196691	-0.7138118	-0.3014681	-0.1619064	0.3226345	0.5755517	0.6835499	0.1612949	0.0238887	0.3444759	0.7017971	0.8542440	-0.0243554	NA	-0.2269706	0.1154792	0.4681067	0.0663575	-0.1656356	0.0448884	0.6409001	0.6474918	-0.202659	-0.3322099	-0.3249633	0.5898805	0.5946355	-0.7343247	-0.7981366	-0.5616333	0.0416844	-0.0012537	-0.4733869	-0.4384114	-0.4384114	0.5617484	0.5506154	-0.2303076	0.3794595	-0.2943173	-0.2460360	0.4599549	0.5767896	0.3056177	-0.3753437	-0.5061129	-0.4665034	0.1338360	0.3526838	0.3520197	-0.7987042	-0.8882871	-0.7168317	0.2118309	0.6219741	0.5499616	0.5672259	-0.9029388	-0.8510811	-0.8446397	-0.1327063	0.2746629	0.6342810	-0.3399754	NA	-0.3625633	0.0174545	-0.3614153	0.2770839	-0.1781304	-0.3749898	-0.7561551	-0.9163723	-0.9417298	0.2986121	0.8895090	-0.4641303	0.110037	-0.1532831	-0.0751925	0.9435165	0.9966214	0.6631747	0.2480829	0.0061375	0.1011153	0.5573916	0.8455913	-0.1153075	-0.0038404	0.7318767	0.3251702	0.0186759	-0.1905569	-0.1993989	0.0270931	0.2937587	-0.0844270	-0.2554244	-0.5212536	-0.4838944	-0.5249709	0.0511894	0.5112096	-0.0639285	-0.0076109	-0.0422883	0.4635081	0.7565138	-0.4563065	-0.3161364	-0.4688658	0.6377848	0.6662755	0.0372568	-0.2064409	-0.1056480	0.1800292	0.3951566	-0.1099762	-0.4011496	-0.3007020	0.6071243	0.7007215	-0.2717594	-0.2842391	0.0840161	0.5432928	0.6296678	-0.1068903	0.0198177	-0.0603440	0.4624991	0.5640090	0.3315959	0.2841998	0.3511119	0.6598365	0.7575759	-0.7980225	-0.3678738	0.2258377	-0.4955377	-0.8470913	-0.9817120	-0.3501899	0.2915814	-0.4838281	-0.9622225	-0.0430636	-0.0518525	-0.0485600	0.5161297	0.9070606	0.1170207	0.1737897	0.1286241	1.0187399	1.106150	-0.0330534	0.0064565	0.1665144	0.4191869	0.4935070	0.2832918	0.2393476	0.2719804	0.5490282	0.7467903	-0.4000075	-0.4221522	-0.3974584	0.2940190	0.663469	NA	NA	NA	NA	NA	0.0439937	0.0675457	0.0362139	0.5647392	0.6537428	-0.8388923	-0.7323111	-0.7322845	0.4872934	1.1128943	-0.5658484	-0.1212817	0.3856831	-0.3041746	-0.5108849	-0.6093013	-0.4794602	0.4787095	0.4617690	0.5540651	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	-1.016137	-1.016137	-1.016137	-0.3214735	-0.2515876	-1.0161371	-0.6799042	-0.8588407	-0.0069869	0.3427612	-0.7036819	-0.7947300	-0.7977836	0.4084916	0.5643806	-1.0161371	-1.0161371	-0.5797672	0.0637566	0.0461789	-0.6935599	-0.3226869	-0.3356710	0.1050190	0.4157617	0.4314276	-0.2771204	-0.7408219	-0.3192856	-0.3103108	0.6856933	0.9015377	0.1553411	0.1803004	0.1974001	0.3191694	-0.7892511	0.6644301	-0.9834166	-0.9771768	-0.6815956	-0.0616504	0.2040595	-0.0850105	0.2673528	0.1487603	NA	-0.0473729	0.5665621	0.6860950	-0.9321679	-0.8910369	-0.7915989	0.7670132	0.6655196
IgG1_DT	0.9424570	-0.0818397	0.5661483	0.6208074	0.0473113	0.7891822	-1.3008831	-1.2968588	-1.2876592	-1.2874832	-0.5644945	0.7324193	0.6149111	0.5775732	-0.0030183	0.8183715	0.3478673	0.2328014	0.1986613	-0.0335467	0.6003308	-0.6102934	-0.3650614	-0.6142153	-0.5315226	0.0993296	-0.5117503	-0.4070039	-0.3899081	0.3168204	0.3371830	0.5832658	0.7161856	0.6432669	1.1034620	0.9062636	-0.6461635	-0.6434617	-0.6083111	0.4102986	0.4883112	-1.0331585	-0.9912817	-1.0533652	-0.0625328	-0.0005056	-0.3667310	NA	-0.4322762	-0.4010375	0.3711740	0.1247379	-0.5968850	NA	-0.6754322	-0.7185473	-0.1760297	NA	0.2520754	-0.6778244	-0.6651881	-0.7049261	0.2578074	0.8737302	-1.0447817	-1.0539844	0.0223305	-1.0764989	-0.4693983	0.2583543	0.8158135	0.2678009	0.3270135	0.3722867	0.7322383	0.8107219	1.0722394	-0.5537885	-0.6493685	-0.5694554	0.7287543	0.7776453	0.3380637	0.5226711	0.2305212	0.9758155	1.0133016	-0.3741552	NA	NA	-0.2101291	-0.8172807	0.5963306	-0.0109271	-0.0153948	-0.1560349	0.0549586	0.1424938	NA	-0.5844670	-0.7028921	-0.7171117	0.0324379	0.2647073	0.6008880	0.1382097	0.1558094	0.0967578	0.1672144	0.3054935	0.9842892	0.6783652	0.7888310	0.7396314	0.5764191	0.7724671	0.8617992	0.9353955	-0.1238372	NA	-0.5417160	0.0945650	0.5409703	0.3948575	-0.2243965	0.2827165	0.5029651	0.4372939	-1.039258	-1.1191037	-1.1109225	-0.1999329	-0.0605236	-0.8959855	-1.0265198	-0.6938305	-0.1668985	-0.3245151	0.3439029	0.3387873	0.3538240	0.6487446	0.5608755	0.5955478	0.8111656	0.4240727	0.4664441	0.8079507	0.9049895	0.7159417	-0.0436921	-0.2317539	-0.1529535	0.6007309	0.7209947	0.7867484	-0.5978274	-0.7025675	-0.5013550	0.9144783	1.2635324	0.7137096	0.6947098	-1.2231416	-1.1874617	-1.1819328	-0.1089917	0.6229944	1.2495885	-0.9664598	NA	-0.6232037	-0.1012208	-0.9973963	0.3289381	-0.5060177	-0.7997848	-0.5379648	-0.7253411	-0.7627990	0.4325591	0.9270990	-1.0648530	0.156047	-0.1308702	-0.0386995	0.5540372	0.5456699	0.9661801	0.7253292	0.3409953	0.4978070	0.8069649	1.0226946	-0.1683763	-0.0813646	1.1678860	0.4769922	-0.1988975	-0.2763712	-0.5394437	-0.0051049	0.5753626	-0.1658183	-0.6052118	-1.2295656	-1.2295656	-1.2295656	-0.2333281	0.5302236	-0.7846868	-0.7615358	-0.7596282	0.3735602	0.9732335	-0.9758531	-0.8305736	-0.8952145	0.7492049	0.9797184	0.1648479	-0.1447002	-0.0281645	0.9469116	1.1102264	0.5319266	0.1335462	0.2956904	0.6369302	0.7027416	-0.2522351	-0.2107886	0.1265060	0.6693423	0.7115257	0.2374718	0.2725452	0.2915343	1.0020640	1.1155217	-0.1385379	-0.2342637	-0.0966579	1.0662279	1.2580264	-0.5048471	-0.0118681	0.4740442	-0.2453297	-0.5833613	-1.2295656	-1.0906038	-0.7049261	-1.2295656	-1.2295656	-0.0801454	-0.0831801	-0.0899433	0.6225805	1.3262603	-0.1274012	-0.0111690	-0.0888594	1.1706192	1.395887	-1.2295656	-1.2134812	-0.9103063	-0.1626222	0.3014830	0.6589980	0.5554252	0.6009903	0.9339061	1.2371244	0.9517679	0.9519849	0.9272730	0.9391086	1.079489	NA	NA	NA	NA	NA	-0.5114877	-0.4786687	-0.5015597	0.3962595	0.3976469	-1.1450951	-1.0809311	-1.1156143	0.1507578	1.3416071	0.3373054	0.3518724	0.2362472	0.2615225	0.3300654	0.1589828	0.1390833	0.8482690	0.9366679	1.0348649	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	-1.229566	-1.229566	-1.229566	-1.1298716	-0.5884227	-1.0064176	-0.7992286	-0.8901421	0.3062131	0.4648890	-0.4613522	-0.5717317	-0.5866888	0.4846333	0.5684800	-0.7830188	-0.7821084	-0.5332994	-0.2250954	-0.3691176	-0.4909132	-0.1670443	-0.1930134	0.1088610	0.3126249	0.2033727	-1.2295656	-0.5768412	-1.2295656	-1.2295656	-0.8293034	0.1270437	-0.7887621	-0.7311879	-0.7304943	-0.2104623	-0.5988740	0.5437683	0.1196995	0.0563592	0.3240271	0.6685617	0.7403128	-0.2143562	-0.0550299	-0.5214272	NA	-0.7253363	1.0583255	1.0854435	-1.2889490	-1.2827878	-1.2647480	0.9185896	0.8999670
IgG1_OVA	-3.5618513	-3.8027656	25.9882812	34.8469124	15.1330204	42.0152283	-1.3170319	-0.7569551	0.5859356	-3.3849423	1.0243077	-4.0293136	-4.0393128	-3.8471842	-4.0393128	-4.0015407	-4.0393128	-4.0393128	-3.9706693	-4.0393128	-3.9459724	-3.4377718	-2.7913857	-3.1680155	-3.8959682	-3.0198331	10.1745625	11.3908920	12.1750240	8.4395962	7.2234111	-3.9942334	-3.9287863	-3.9680545	-3.7586236	-3.8502495	-3.9287863	-3.9156969	-3.9222414	-3.8109813	-3.7062659	-2.4104118	-1.6119564	-2.7638266	-1.1014686	-1.1211026	-2.8358185	NA	-3.1303306	-3.0583389	-3.5911458	23.8885612	-3.3070381	NA	-3.5884609	-3.6800871	-3.5911458	NA	28.7067204	-2.5543957	-2.5413063	-2.8096395	-3.3087368	-1.8213873	-3.9156969	-3.9418757	16.3527870	-3.9811440	-4.0393128	-3.6342740	11.3476372	-3.9813890	-3.9159420	-3.8766737	-3.9290314	-3.9028525	16.9573936	-3.7065110	-3.8374052	-3.7719581	-3.7233150	-3.8159289	-3.9421208	-3.9159420	-4.0073309	-3.8838458	-3.9332399	5.1419463	NA	NA	10.5413380	0.2594790	0.6766319	-2.4368358	-2.4499254	-2.6242967	-2.3896747	-0.1175466	NA	-3.2614703	-3.5625272	-3.5133901	-3.6986179	-3.6615725	0.9508867	-4.0393128	-4.0393128	-4.0393128	-4.0393128	-4.0393128	-3.4621222	1.2625399	-0.2458615	-4.0393128	-4.0393128	-4.0393128	-3.9523509	-3.9908490	15.0016613	NA	8.4134789	25.1010590	6.1406293	-3.8881869	-4.0393128	-3.9010196	-3.6571970	-3.7470264	-3.875354	-4.0214834	-3.9459343	-3.8881869	-3.8496885	6.1855435	3.4197702	13.7953815	8.8611774	5.4797416	0.3046355	0.1974378	0.6093035	0.4287596	-1.3428276	16.1304379	-0.6884089	14.1500969	17.2249851	14.6931438	18.8883076	-1.8352926	-1.6192856	-2.6856232	-2.3132513	-1.7340953	-2.0155182	-1.8477588	0.8914032	-1.2694817	1.2468491	-3.7176778	-1.7916610	2.0814748	-0.5036886	-2.2342632	-1.6136434	-0.9366038	-1.6162903	-3.2786484	-1.6545336	4.5535979	NA	-5.0614347	-5.7060237	3.5625405	-5.6863718	-5.7335367	-5.7649798	-6.0617266	-6.0617266	-6.0617266	-6.0617266	-6.0322485	0.8947892	-5.128252	-5.9320230	-5.7826667	-5.5468416	-5.6647539	-1.2182193	-4.2537332	-5.7158499	-5.2756424	-4.4443583	-4.1672635	3.2789197	1.0936055	-3.7488432	1.7224727	1.4866476	0.7791715	-3.8056650	-4.3500280	-4.3893323	-3.8842733	-4.5465493	-6.0617266	-6.0617266	-6.0617266	-6.0617266	-6.0479703	-6.0617266	-4.7808228	-5.6806822	-6.0444531	-5.8498974	9.2374382	9.8152103	10.0274525	10.4991035	8.8935261	34.3331795	18.2990246	24.6584454	28.1054249	26.5371876	-6.0361791	-6.0617266	-6.0617266	-6.0538659	-6.0263529	11.8114510	13.0927677	13.0456028	14.7769527	14.6138420	-1.9862931	-0.3197942	-2.3871961	-1.5166075	-1.7995980	-2.2260487	-2.8804638	-2.1533358	-2.5345869	-1.6364856	13.7574215	10.9786148	8.4611797	7.4471316	11.7136040	-5.6961975	-5.6824412	-5.6529627	-5.6470671	-5.7767711	1.7771063	1.6395411	0.8731093	-0.9014761	-0.6990595	-6.0601540	-6.0011978	-6.0601540	-5.9677892	-5.832190	-5.8577580	-5.8852711	-5.8420362	-5.7988014	-5.7418108	-6.0617266	-6.0617266	-6.0617266	-6.0617266	-6.0011978	-5.9383111	-6.0090585	-5.9894066	-5.9658241	-5.912764	NA	NA	NA	NA	NA	1.3294306	1.0680575	0.4332943	-0.6279192	0.3330688	-4.0375600	-3.1414237	-2.5086260	-0.1778860	2.2982793	0.3428950	0.6416068	-0.6121976	-1.1192219	1.2960219	-5.1361127	-4.3991585	-2.7464163	-3.7879779	-4.5485144	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	-5.183484	-1.186452	-3.404968	-4.2028441	-2.9392138	2.0762105	3.4204149	0.9796233	4.0866208	3.2238936	5.7802196	4.3318591	3.8169742	1.8497982	3.9584689	-2.6662560	-2.9630027	-3.0573328	-3.4700270	-3.7707043	-3.7239108	-5.6848192	-5.5452895	-5.5708370	-5.6474805	-5.6356893	-4.3482594	-3.7987075	-4.8258057	-4.8218751	-4.1421084	-2.7939739	9.2095127	10.5026207	11.3181839	11.3004971	-3.8111737	12.1101627	14.2306252	11.7131901	11.1747227	12.4992752	11.0017853	-3.8485723	-3.5888038	-4.0393128	NA	-4.0393128	-4.0393128	-3.9789696	-4.0293136	-3.9663835	-3.9286256	-3.8279376	-3.8656955
IgG2_PT	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.8406477	1.5281420	0.6868253	0.2601881	0.4786067	0.7698317	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.6713467	-3.1539655	-3.0160909	-3.7441528	-2.5064473	-2.7976723	-3.8406477	-3.8406477	-3.8406477	-2.0332069	-1.4810634	-3.5698483	-3.5325487	-3.7190473	-3.4206495	-3.4206495	-3.6444478	-3.6444478	-3.6444478	-3.1968510	-3.2714505	-3.4206495	-2.3016577	-2.8238537	-2.5254560	0.0855250	-3.8406477	NA	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.8406477	NA	-3.8406477	-3.8406477	-3.8406477	NA	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.5698483	-2.8238537	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.3460500	-3.8406477	-3.7704108	-3.8406477	-3.8406477	-3.3731992	2.4856710	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-1.3871417	-1.7843533	-1.4891286	1.7033253	19.5073929	-3.5718050	NA	NA	-3.5718050	-3.8406477	-0.8232322	27.0134850	25.4246368	24.0504990	22.6589165	25.8513718	NA	-1.4367929	-1.5857472	-2.7988529	-1.5709863	-0.1794038	-0.7757597	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.6003664	-0.7282872	1.4079700	-3.6161904	-3.4632239	-3.8406477	-1.0157590	1.5081892	-2.0865250	NA	-0.8245506	-1.4746585	-2.2394915	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.7691569	-3.539707	-3.3867407	-3.8406477	-3.5397072	-3.6161904	-2.3159747	-1.4364171	-1.8953166	-2.7748742	-1.7805915	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.8406477	0.8383012	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-0.7282872	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-0.8592072	-1.0605941	76.0028992	70.7107544	64.9300995	-3.8406477	0.7196202	105.8876877	128.5325775	1.6685572	3.7039995	1.3021779	1.7436142	2.6112213	0.9332461	-3.8406477	NA	-9.7116947	-9.7116947	-3.8406477	-9.7116947	-9.7116947	-9.7116947	1.2333002	-7.5816178	-7.5816178	3.5930204	13.3708296	-3.8406477	38.513767	20.3549767	28.0375443	44.7994995	49.6884041	-3.8406477	-3.3911283	-5.4863729	-6.1847878	-1.9942985	0.7993612	-9.7116947	-9.7116947	-3.7665195	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-3.6822629	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.0132809	28.0956154	26.3495789	23.5559196	27.7464066	37.5242157	-8.2800331	-6.8832030	-7.5816178	2.1961908	2.1961908	29.4343719	16.8629036	18.9581490	14.0692434	28.0375443	-9.7116947	-9.7116947	-9.7116947	-8.8089838	-5.3169093	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.0132809	-9.7116947	-4.8227911	-7.6164503	-6.2196207	-5.5212059	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	14.9371233	18.4291992	10.7466326	14.5879164	15.6355371	-9.7116947	-9.7116947	-9.7116947	-5.4559007	-0.2177887	2.2266636	-4.0590706	-6.1543155	0.1314187	9.210813	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	2.9250784	3.6234932	0.8298335	4.3219080	9.210813	NA	NA	NA	NA	NA	20.7622566	16.5717697	18.6670151	22.1590881	32.6353111	-8.2800331	-9.6768627	-8.2800331	-6.8832030	4.2914352	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	-9.711695	-9.711695	-9.711695	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.7116947	-9.2695827	-9.7116947	-9.7116947	-9.7116947	-7.6164503	-6.9180355	-9.7116947	-9.7116947	-9.7116947	-8.8089838	9.3498039	-3.8406477	3.0640697	7.9529743	2.3656549	15.6355371	17.7307816	15.4965467	-3.8406477	14.0997171	16.8933754	14.7981310	17.5917892	-9.7116947	-9.7116947	-9.0132809	-5.1719985	-3.8406477	-5.8704133	0.2704101	2.3656549	1.6672401	5.8577290	21.9212723	-3.8406477	-3.8406477	-3.8406477	NA	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.8406477	-3.3002813	-3.4465971

# abtiter <- head(results$abtiter$group1)
knitr::kable(results$abtiter$group1[1:10,], "html", align = "lccrr", booktabs=TRUE, border_left = T, 
             border_right = T, caption = "Ab-titer After Imputation")  %>% 
  kable_styling("striped", full_width = T) %>% 
  scroll_box(width = "100%", height = "400px")

Ab-titer After Imputation
	1	102	103	104	105	106	114	115	116	117	118	131	132	133	134	135	138	139	140	141	142	146	147	148	149	150	153	154	155	156	157	160	161	162	163	164	167	168	169	170	171	174	175	176	177	178	181	182	183	184	185	19	191	192	193	194	195	2	20	201	202	203	204	205	208	209	21	210	211	212	22	223	224	225	226	227	23	241	242	243	244	245	248	249	250	251	252	255	256	257	258	259	27	274	275	276	277	278	28	281	282	283	284	285	29	293	294	295	296	297	3	30	31	324	325	326	327	328	332	333	334	335	336	342	343	344	345	346	349	350	351	352	353	355	356	357	358	359	360	361	362	363	364	369	37	370	371	372	373	38	385	386	387	388	389	39	397	398	399	4	40	400	401	405	406	407	408	409	41	45	46	468	469	47	470	471	472	475	476	477	478	479	48	483	484	485	486	487	49	490	491	492	493	494	498	499	5	500	501	502	506	507	508	509	510	513	514	515	516	517	521	522	523	524	525	529	530	531	532	533	537	538	539	540	541	546	547	548	549	550	554	555	556	557	558	562	563	564	565	566	569	570	571	572	573	577	578	579	580	581	585	586	587	588	589	593	594	595	596	597	601	602	603	604	605	608	609	610	611	612	616	617	618	619	620	623	624	625	626	627	630	631	632	633	634	636	637	638	639	640	643	644	645	646	647	650	651	652	653	654	657	658	659	660	661	664	665	666	667	668	669	670	671	672	673	674	675	676	677	678	681	682	683	684	685	688	689	690	691	692	695	696	697	698	699	70	702	703	704	705	706	709	71	710	711	712	713	716	717	718	719	72	720	723	724	725	726	727	73	74	77	78	79	80	81	87	88	89	90	91
IgG_PT	3.7817969	1.6860446	2.103011	2.3629937	2.283473	3.225232	0.4426608	0.3350511	1.2160311	1.0061293	5.4732518	9.8416200	7.9445238	7.7529464	8.7641244	9.0980268	2.3076434	1.6299938	1.2789178	10.2521100	9.8400912	3.5303845	3.6955504	4.2190895	9.0965466	9.1659989	4.8708768	5.1196618	1.4647737	6.0650558	7.2101054	5.8285074	0.6608386	0.3102522	1.506294	2.0228410	3.5332835	0.4564528	0.2530246	7.4170613	4.9169207	0.4611731	0.4843905	0.4297113	4.3838286	7.154471	0.3488429	3.487311	0.3075590	0.3007483	1.4009523	1.2146733	0.8112681	3.329797	0.4590783	0.6353118	1.3727465	3.829518	0.8416719	0.7856219	0.3500786	0.7559183	1.152298	2.5728302	0.8353930	0.3500786	0.6507721	0.6384180	0.1772246	2.4780259	6.394069	1.1167941	0.9102664	1.1234391	2.0109501	4.1275039	6.994370	0.2669590	0.3062060	0.2340879	1.1160936	1.8974905	1.7487882	1.6040701	1.6954842	7.8800101	14.5987287	0.6897674	3.632998	3.532581	0.7591982	0.8572836	2.138527	1.399336	1.878899	2.352770	4.0408192	4.246706	3.579549	1.1767740	0.6573453	0.7252734	1.5668107	2.3424156	1.730973	0.8361788	0.6751585	0.6169715	4.9305997	6.5686569	2.3415756	1.530528	7.825565	1.2845802	1.2037919	1.2014067	7.8977380	8.7658324	1.1251853	3.503702	0.9276462	0.9003832	1.553392	1.0271783	0.9283986	1.0148599	12.3787074	15.7200837	0.2490277	0.2795620	0.1772246	0.5602765	2.188695	9.7174573	10.5061297	9.3232961	12.8292766	10.8114657	5.3144932	5.1541200	5.6544499	12.0771108	15.0319047	0.1772246	3.841114	0.1772246	0.1772246	0.3382187	0.1772246	3.217444	0.5588589	0.5193720	0.3331404	1.0264554	2.9507773	2.324483	2.9906166	2.7654865	0.1772246	3.3087199	5.978848	3.5859375	5.9770603	16.7630420	8.7676120	6.1179676	6.6955514	11.7673249	5.327744	0.3562148	3.339096	0.7943702	0.7803564	0.3426201	0.9134872	1.8360617	2.5811281	0.9083607	2.3120754	2.1999650	7.702713	14.207447	0.3188896	2.3447742	3.8652701	4.3977942	14.006582	17.647832	9.0236077	3.0407922	4.4748702	4.1945944	3.8816197	4.9583459	0.5234368	0.5234368	10.7202544	0.6939378	4.454305	16.9102263	1.3268940	1.1213584	1.1400435	17.0153308	18.9819331	0.4061887	0.3618116	0.3431265	3.192597	19.626100	0.8756261	0.8639479	0.9013181	8.520148	14.366233	0.9036782	0.9176919	0.8803220	6.462481	10.486774	0.1469450	0.3454735	0.2707334	0.2146783	1.6207284	6.5862808	8.7046990	6.6563497	6.497527	8.307642	3.1673717	2.4082913	3.099638	8.744859	15.961961	2.573630	2.779166	2.963681	8.914870	12.350584	0.1982930	0.2450056	0.2917182	2.0854833	3.344388	-0.1211975	-0.1679101	-0.149225	0.2291472	1.0139194	10.9099898	10.0714984	10.2443347	10.2957187	11.3911300	0.3879702	0.5935059	0.3225725	1.8337260	4.472990	0.7873631	0.8807883	0.7336435	4.365551	7.509311	3.9568150	3.3915923	3.9101024	4.3165021	9.2633700	0.1450646	0.1777635	0.1263795	0.9882274	2.062618	2.3966134	2.4620109	2.5390868	2.838048	4.568750	3.591667	3.573765	3.316521	3.573189	3.172793	1.2166529	1.1162205	1.1676044	2.835245	3.818546	-0.0328987	0.2987609	0.2707334	1.1676159	4.178245	0.0142691	0.046968	0.0422966	0.7476573	1.3175516	-0.0118895	-0.0399170	3.2323027	4.1478705	5.4885230	3.486150	3.106960	3.417495	3.355517	3.278897	2.878338	3.114304	3.251570	3.310318	3.068564	-0.2081070	-0.1987643	-0.2104425	0.3687940	0.9924078	0.0208094	0.0021245	0.0254807	0.4599082	1.814574	0.6911111	0.5252814	0.7378240	2.2676625	4.294990	-0.0698135	-0.0511286	-0.0231009	1.4249907	3.2701395	0.3634884	1.8313904	1.7566502	1.803363	5.218056	5.769265	5.3371735	0.3369541	4.9471231	4.5921068	6.3718581	9.025135	3.8675702	4.3580527	4.2716341	5.925262	0.4889617	9.8187594	0.4767241	0.5608070	0.4767241	1.051290	3.347215	1.0315123	1.0712762	0.1772246	3.585795	0.1772246	0.3945796	0.3513114	2.5083535	2.0635998	2.0158827	28.430694	22.1118178
IgG_PRN	2.4563735	1.3143675	1.488714	0.6877558	11.363958	12.674273	1.1993692	1.0162361	2.1009490	4.8634157	15.1422997	0.6824468	0.6642079	0.6654369	0.6936938	0.7124655	1.9433073	1.3728654	1.0861459	0.9103172	0.8123636	2.4422853	0.6981647	0.7058406	0.7744950	0.8018494	0.7669365	0.7726382	2.2716668	0.7040254	0.7154951	2.1365399	11.9797459	5.6134758	10.162282	11.7060966	1.5421560	1.9461535	1.0053993	0.7862365	0.7667820	0.6427996	0.6704376	0.5988672	0.8223851	28.949810	1.2390833	2.221635	1.1486782	1.1104658	3.9100759	6.5270791	0.9561679	2.244766	0.6810530	0.8206247	5.4117756	1.696954	4.6238747	1.3065499	0.6631942	1.2361733	4.638808	0.7016932	1.0028290	0.5801951	3.3215871	0.8468150	0.7833140	0.7498286	8.803440	5.4776816	4.4513016	5.6525126	6.7383385	0.7723659	6.869021	2.8393798	3.0887551	2.3739307	4.0072155	4.5451317	1.5506986	1.4796728	1.4410284	0.8486624	0.9812944	0.5059786	2.144818	2.452807	0.5221035	0.5335093	4.929331	1.450982	2.003458	2.837615	0.7257863	6.568772	2.920879	3.6192915	1.9613595	2.3261135	3.8745801	4.0546465	3.644286	0.7450883	0.6658421	0.6205246	0.7466885	0.8189173	1.4633732	2.741334	6.622748	4.3067522	3.8624418	3.8598001	0.7989117	0.8257382	1.5507479	2.410907	1.3474368	1.3084917	8.469993	0.8884406	0.8345673	0.8656404	0.8706050	0.9416180	0.4715011	0.4830908	0.4141390	1.4892002	10.225124	0.6216878	0.6326127	0.6174928	0.8074869	0.7918556	0.7284145	0.7341394	0.7344980	0.8121042	0.8855969	1.2003038	4.605201	0.8018270	0.3979831	4.4716144	0.8319964	4.054485	0.5594722	0.5447465	0.4640931	2.2861807	0.8631575	3.103709	1.9318850	1.8594505	0.6836025	2.1603873	4.622971	0.7236062	0.7954059	0.6696587	0.5475457	0.5037029	0.6691146	0.7412131	4.439258	0.4314735	1.735439	-4.4400496	-4.4346561	0.4309371	-4.4342413	-0.4194260	3.9614663	-2.4343700	-0.9530513	-0.4677606	3.870674	7.361890	0.4275451	-4.5495124	-4.3388834	-4.2700105	1.021994	4.666999	2.1773953	-1.7947378	0.5263314	0.4245435	-0.7814224	1.9983842	-2.8699431	-2.8775496	6.5329800	-2.9137840	6.965317	7.6554284	1.1722554	0.9703391	1.1513723	7.4575229	7.6841946	-3.8432517	-3.7532191	-3.9059010	1.105357	6.076924	5.1333122	4.7901926	5.0024815	6.798153	6.347576	-0.1793005	-0.0563529	-0.1534386	7.281507	7.392976	2.6929212	4.7765312	4.4186139	2.6978998	7.0496111	-1.9163027	-0.3136957	-1.0400412	8.525536	8.419322	6.9309173	7.1531634	6.988588	7.487294	7.396708	1.116007	1.228859	1.304094	5.122387	6.520450	2.3541970	2.2969413	2.5053575	7.0307722	7.744118	3.9524770	3.2366421	3.483367	8.8272347	8.8730111	-4.5495124	-4.5495124	-4.5495124	2.1579113	4.7145038	-0.9881475	-0.9212108	-1.2942028	-0.1233649	1.573700	-4.1538081	-4.0354242	-4.0358391	1.038069	6.657151	-4.4510770	-4.4253535	-4.4668431	-3.8222322	0.2076576	2.1523426	1.6584774	1.6454773	5.9692521	6.201456	-0.6140492	-0.5848682	-0.7259328	2.204343	6.713577	2.134601	1.789420	1.676802	1.717128	2.050406	5.9832959	5.6502724	5.8123584	6.679492	6.458767	-3.5485058	-1.6477263	-1.5138531	3.5018311	8.469110	-1.6589985	-1.689009	-1.0522814	7.6427050	7.9098983	-4.1269026	-4.0811257	5.8748693	4.8966818	6.6789389	2.319098	1.901249	2.452256	1.955487	2.245250	2.066583	1.692179	1.884569	1.953446	2.224087	-4.4748616	-4.3124986	-4.2625728	5.7444549	6.8974524	2.5200162	2.6173787	2.7685394	6.5241828	8.055565	-2.3049526	-2.7892752	-2.4100599	5.6542840	7.381775	-1.1642671	-1.2256718	-1.4486094	3.1550825	7.0578756	0.4840468	2.3302681	2.2684486	1.945244	5.168437	5.552769	0.0612640	0.4796624	-0.0845029	-0.1528225	1.9299580	6.221509	-1.3248286	-0.9635923	-1.0449119	4.984088	2.1727662	5.4317613	-1.6899409	-1.2018843	-1.4853969	2.264438	6.105411	3.5920691	3.6241026	0.4125820	2.112429	0.4182278	9.0745931	8.2933097	6.8784099	5.5793700	5.2823372	8.183027	6.6240039
IgG_FHA	33.2427640	2.6021032	6.290375	3.7472694	71.597443	22.154032	2.7001369	2.4102726	2.1237319	2.6128628	1.6479335	3.8477664	3.7336872	3.7330718	3.8216405	3.9211776	11.2967730	6.6641798	2.3148267	4.5008059	4.4656343	2.5557477	3.2848244	3.3298168	3.7185485	3.6566532	3.3440580	3.3399189	12.8247833	3.8133035	3.9275372	14.8183389	2.3968794	1.8895330	17.672099	1.6479335	4.7423177	2.0528865	1.8210397	3.8378706	3.7373376	3.6393855	3.5191681	3.3291323	4.4656343	64.099610	2.0570953	5.360074	2.0374496	2.0285852	3.5284925	2.5892901	1.8211308	5.240864	1.7159116	1.7638037	2.8182948	6.130161	2.2674592	2.4774029	1.9243081	2.4568856	3.786901	3.5351245	3.6200442	2.2961822	2.1328473	3.2026999	3.6781459	3.6506953	1.647933	6.2038093	5.4019914	7.2362094	12.8583040	3.9618824	12.326140	1.8731360	1.9119792	1.8345151	3.8992777	7.2961907	2.2626193	2.1896954	2.2168345	3.6905780	4.6780334	2.1187356	5.426103	4.909387	2.1964900	2.2192950	2.544473	3.788144	4.786701	8.326727	3.7217841	1.647933	5.583493	4.3686357	2.8925641	3.0568244	3.8186474	4.7423177	2.331974	2.2801850	2.1665595	2.1170490	3.7435522	4.3191247	5.6984048	2.226064	4.295873	2.3378975	2.2825758	2.3184822	3.5804384	4.0040545	2.5217330	5.209394	2.3519258	2.3171105	5.598934	1.9814105	1.9462047	1.9779134	3.7950518	4.2546902	1.8171673	1.8294659	1.7027001	5.4705725	1.647933	3.4970756	3.5334256	3.4901159	3.8746567	3.8871064	3.3927720	3.4236524	3.4089572	3.9090049	4.3548112	1.9383206	1.647933	1.7629976	1.6479335	3.5491121	3.9324791	11.365495	2.0613317	2.0462437	1.8540301	2.8676822	4.0617237	5.910462	1.6479335	56.5415349	3.7532151	11.1851416	1.647933	3.8771815	4.3867493	4.1209726	4.3602328	3.6444070	3.5722692	4.3750882	1.647933	1.9221983	5.249244	8.7799120	8.8140717	1.9258404	8.8166990	13.1602311	19.3050294	3.4414032	9.5586109	9.6584616	24.374709	38.076676	1.9272394	-0.2701755	0.8452687	0.7046885	20.811593	35.747250	10.9500399	2.7201087	5.5028076	5.7379837	6.5420494	25.8002172	6.7933955	7.3557162	1.6479335	8.7470655	12.212957	20.9341836	10.8570824	6.6449327	8.7326136	14.4215112	19.2879510	-0.1039171	-2.9339137	1.1363416	3.750870	8.696138	-2.2719083	-2.1589184	4.0160975	7.135138	9.995353	-1.1352763	-0.2379279	-1.9117513	6.323355	10.292445	7.1069980	14.7075238	10.9696674	8.9989176	24.9633050	24.5533891	40.1512189	34.2350278	42.629109	56.497929	-3.3782430	-3.3427691	-2.714757	-3.214014	-2.357394	-2.764595	2.873063	4.307769	2.519642	4.563966	-3.0037131	-2.1865087	-1.1012826	5.2537284	5.682038	4.8896513	2.6587627	1.142599	8.0297127	30.0902867	22.3071389	17.1542859	12.6425810	17.9806867	20.9354978	-3.5797439	-3.4785790	-3.5666060	-3.5482116	-3.566606	-3.5508399	-3.5390153	-3.5560946	-3.453617	-3.450988	-3.4557586	-3.5267062	-3.4505038	-3.3559070	-3.3191199	-3.5153661	-3.4142013	-3.5179935	-3.4733233	-3.368217	-3.5692334	-3.5179935	-3.4917178	-3.535074	-3.461500	5.772679	5.586885	5.473638	5.743476	4.816559	-2.4687157	-3.4082074	0.6383986	3.203001	4.171297	0.9884768	7.6351590	8.0187979	21.2530408	65.626442	6.8538322	6.602890	8.7286720	19.7267709	23.1072640	-2.9391694	-3.5092711	0.5398612	-1.0025787	1.4358954	5.386977	5.011379	5.118341	5.189444	4.601762	4.301309	4.779635	4.942936	4.857799	4.682052	-3.5981383	-3.5981383	-3.5981383	-3.5981383	-3.3834109	-2.8419452	-3.5211968	-3.5435328	5.5915499	8.637015	-2.2613978	-3.5831141	-3.1955333	-3.2585969	7.182436	-3.5981383	-3.5981383	-3.5981383	-3.5503545	-3.5004287	1.9190886	-3.5293336	-3.5674348	-3.506998	-3.510940	-3.464956	-3.5666060	1.8813744	-3.5377011	-3.5679193	-3.4825206	-3.511424	-3.2940707	-2.6897073	2.7101474	2.354099	2.1690817	6.2798324	-3.4623275	-3.5556102	-3.4321094	-3.470211	-3.225838	6.9963622	7.1423321	1.6667752	5.384051	1.6687026	3.8751101	3.6501656	5.8062506	4.3940792	4.2261124	19.715300	35.0457616
IgG1_PT	14.1694050	4.3421903	3.264122	5.1102343	7.935415	37.077311	-3.9551249	-3.9178162	-3.7774353	-3.4759016	4.6776519	45.9702282	39.7062397	33.5415211	13.6924791	51.3639126	3.6442051	2.5373783	1.8749733	13.2317314	44.9085712	9.7776117	17.1140156	9.9968967	12.2005701	38.5799656	-2.0539370	-2.0668383	-2.0137138	20.3454819	23.6957150	-3.7083225	-3.6658812	-3.6470184	1.853910	2.2712545	-3.8380060	-3.8387918	-3.7822027	27.9854794	32.1447735	-3.8529396	-3.7994938	-3.8812342	11.3640156	28.805235	-3.8945951	9.686367	-3.9228897	-3.9252472	-0.2936954	-0.5338879	-2.3816242	9.602642	-2.8256912	-3.0394716	-2.5033808	10.023172	0.4949217	-1.8801823	-1.9949322	-2.2338638	9.829051	28.4924221	-3.5094757	-3.5354118	-1.4363070	-3.6014328	2.8477678	14.7762575	22.158895	-3.2028790	-3.0564604	-2.8451509	-0.6987858	7.8459134	38.506933	-4.0065184	-4.0248203	-4.0081825	-0.1117315	1.9588790	0.0274849	1.4542360	0.4573975	33.8589725	48.5303288	-2.1047382	9.747009	9.567558	-1.0631685	-3.5014143	5.596838	3.252025	3.292790	2.136784	9.4209852	19.017946	9.648085	-1.2312174	-2.3642988	-2.1024504	0.8016758	5.2501125	6.886851	-2.4063702	-2.2877674	-2.6901121	16.9901638	23.9712696	16.5320435	7.086546	31.811670	-0.9048443	-1.6678638	1.1603537	28.9207191	44.5618382	-3.6668501	9.613192	-3.9046640	-3.2719402	-2.234612	-0.7787256	-2.4455023	-0.4854984	51.8917141	55.4687634	-4.0042191	-4.0649452	-4.0467834	-3.9380054	-3.900170	34.5519314	16.4885712	44.6367207	47.7912731	42.4162388	26.6598358	27.7005081	28.6850243	53.3562107	50.1837215	-4.0634556	14.471896	-4.0648775	-4.0634556	-4.0069389	-3.7976294	10.596800	-3.8224802	-3.9881067	-3.8971195	-3.0597134	5.2568302	11.384626	-1.1774387	-1.9444370	-0.1822596	12.2364902	29.946163	3.8975530	2.1057043	17.2944965	19.8037663	20.2629700	30.1760883	37.8737354	28.156490	-3.8671951	9.665296	1.4537268	2.9943190	-3.9076405	6.9074235	2.1932111	0.5909948	0.0339527	-0.5186348	-0.5186348	23.142837	58.114283	-3.9750481	1.6977930	-0.2125416	0.1572008	69.268175	87.077417	-1.9258556	4.8406010	0.5269423	1.2664270	7.3671727	11.1570301	0.9607372	4.2267928	44.1506405	54.3884792	11.744884	0.5293713	1.2380438	31.3104057	51.2764835	6.2911868	1.0223608	1.0026407	1.3723831	0.8793936	6.980139	97.043169	4.8855186	6.0255566	5.7174382	33.632971	77.601473	-0.5186348	-0.3186502	-0.5186348	16.500999	38.284975	-0.5186348	-0.5186348	-0.5186348	-0.5186348	-0.0276709	-0.4590368	-0.5186348	-0.5186348	2.437277	3.854622	6.4266086	7.1969047	22.325522	58.929995	64.075571	9.168366	10.061909	8.798623	34.927069	58.035952	-0.5186348	-0.5186348	-0.4449310	6.4569225	11.818184	-0.5182314	0.0363817	1.915904	-0.2101126	-0.5182314	10.0502319	10.7280922	13.3470993	7.0614829	9.0950651	0.8185291	0.5104113	0.5720348	19.0591431	51.041838	-0.2290735	0.5104113	-0.2906971	15.484968	41.952345	11.2332563	11.0483856	13.3592739	30.1209183	50.8572903	-0.5186348	-0.5186348	-0.5186348	1.9585676	8.583115	0.1406689	0.0790453	0.3255396	2.143439	7.936066	9.872279	9.815292	9.745973	9.776571	9.516690	-0.2914572	-0.4763279	-0.4147043	6.302278	11.047302	-0.5186348	-0.5186348	-0.5186348	0.8966846	12.112197	-0.1484890	1.392103	6.9382353	0.1904411	0.5909948	-0.5186348	-0.5186348	5.6244178	8.4591074	14.1284876	9.603986	9.558601	9.498898	9.570776	9.373489	9.269067	9.435706	9.506092	9.479372	9.325499	-0.5186348	-0.5186348	-0.5186348	-0.5186348	1.2068291	-0.4418974	0.0166616	-0.3186502	3.4984007	7.719623	0.0480585	-0.3216839	-0.3337631	2.7595010	8.891059	-0.5186348	-0.5186348	1.0684242	5.8719950	7.9672008	-4.0649452	2.1129498	1.8356433	10.062406	19.490831	15.485292	10.9588661	-4.0649452	9.0485315	9.9112625	25.7453136	48.546080	9.0451174	10.8630171	10.8322048	18.103800	-4.0649452	40.2575169	-0.5186348	-0.5186348	-0.4721680	3.283800	6.056866	-3.9177513	-2.8327532	-4.0649452	9.696084	-4.0649452	-4.0649452	-4.0064240	0.0244770	0.9742966	2.6664047	65.839479	61.7238560
IgG1_PRN	2.3302748	1.5284059	1.312762	1.2526705	2.527934	3.265095	0.0390971	0.0590872	0.0821337	0.2282987	1.3172517	1.5933367	1.3866632	1.1822581	0.9813661	2.6184084	1.5628614	1.4597622	1.2189076	1.9637829	3.0978544	1.5634851	1.9696232	1.4077818	1.6176033	2.6763711	0.9227964	1.0455735	1.1016994	1.9540830	1.9487069	2.8577771	3.2810178	2.9498637	3.388224	3.0529110	1.5253772	1.5015535	1.6049279	2.6392653	2.6572073	0.2182266	0.2564869	0.2068791	2.4799261	2.494333	1.5344670	1.711772	1.4303499	1.4227455	2.0974634	3.4107301	0.5112988	1.695173	0.4193609	0.3869227	2.0340385	1.538354	3.5069754	1.2563959	1.2282650	0.9932815	1.216798	1.8467287	0.4487394	0.4134495	3.3707347	0.3858831	2.1754551	2.6102283	3.572792	2.6664200	2.8220980	2.8472533	2.9649036	3.2045155	3.831099	2.1541934	1.9555868	2.1198876	2.7180581	2.6545365	0.1403986	0.1881659	0.1485127	3.0984557	3.0723393	0.0238651	1.685160	1.718937	0.0342560	-0.0141609	2.786160	2.382360	2.349357	2.073078	2.5663629	2.995393	1.927839	2.4784527	2.2797220	2.1578960	2.2026846	2.4202812	2.839402	0.3122900	0.3543020	0.3091780	2.3934937	2.7089052	2.4153533	2.852041	3.173893	2.5625563	2.3627982	2.8233755	3.1601455	3.5226336	1.2882682	1.708161	0.9038074	1.6093969	2.937497	0.8032363	0.5019588	0.8197800	3.1149361	3.1358113	-0.0158887	-0.0234718	-0.0282212	1.4140307	2.227170	0.2206866	0.1505824	0.3618797	2.9305789	2.8109226	1.9338893	1.9715561	1.9741384	3.0881448	3.0998771	0.5012584	2.971099	0.4432144	0.5231231	2.6921659	3.0793607	2.771314	0.0864460	0.0155751	0.0531577	1.5565294	2.8458920	2.844585	1.2621173	1.0889677	1.4683586	2.1933622	3.179812	2.6489720	2.9351912	-0.0074404	0.0104948	0.0202063	0.9641238	1.8341730	3.209409	-0.0229985	1.567424	0.1029514	0.5266770	-0.0245342	1.6743126	0.3986245	0.0524044	0.9115956	0.5980952	0.5256444	2.207231	3.854032	-0.0308375	0.0867547	0.0518609	0.0593615	1.836172	2.469423	0.2108315	1.4144572	0.7786514	0.9948623	1.6289289	2.1073322	0.2712243	1.0600843	3.1672695	2.3799059	1.283796	0.2048064	1.1709074	1.9097096	2.5195353	1.6099602	1.1066637	0.0762882	0.0853106	0.0741141	1.275177	2.601956	2.7518251	2.7445419	2.6213810	3.149788	3.399697	1.1595169	1.3507805	1.2899066	3.163028	3.212814	2.3311524	1.7011079	1.9314502	2.5289924	3.0037544	1.0234513	0.4281374	0.5911381	4.145846	4.371568	3.0563030	3.0950015	3.113264	3.219630	3.473072	1.716861	1.968618	1.821596	2.522244	3.044889	2.0835171	1.9920975	2.0759077	3.0348885	3.505846	1.8020933	2.2940302	2.919455	2.1908708	1.7132283	0.0497955	0.6106504	1.5094639	0.3631872	0.0478388	2.0224257	2.0028589	1.9293212	2.5809977	3.342519	0.1114752	0.1879480	0.1546848	1.567828	3.458070	0.0628304	0.0496230	0.0951154	0.4954697	0.9297396	1.7569720	1.6677265	1.6594651	2.5938790	3.230881	1.3466169	1.2440009	1.2966133	2.060798	3.169517	1.673555	1.664973	1.580009	1.653769	1.676105	2.7781096	2.7048435	2.6694062	3.186345	3.168626	0.3273152	0.3969940	0.4157454	2.2181554	4.196013	0.5040125	1.561152	2.6222601	1.0687263	0.6059219	0.1113994	0.5721928	3.0105174	2.8917589	3.0181265	1.562675	1.435458	1.583937	1.518885	1.738008	1.536816	1.498083	1.588868	1.603002	1.497155	0.0470462	0.0819081	0.0618298	1.1310358	1.5319337	1.8376083	2.0833867	1.8244553	2.9730146	3.301245	0.6200984	0.4940568	0.4643809	2.3768530	3.027334	0.6386321	0.6038469	1.2180208	2.2362993	2.3789725	0.0080701	1.5885905	1.5828292	2.079060	2.521917	2.476099	0.8996878	-0.0081841	0.8347920	0.8418577	2.0059025	3.366325	0.8736489	0.9720254	1.0221920	2.370711	-0.0113838	3.2097380	0.9260437	1.0952947	1.2625892	2.311957	2.482784	1.1235616	2.1912582	-0.0151273	1.571395	-0.0358610	2.4212728	2.8397937	2.9442296	3.0789030	3.2451210	3.710240	3.6079135
IgG1_FHA	3.9798983	1.3074942	2.775139	2.7162170	2.610007	4.466120	1.1000254	1.2964045	1.0654218	1.0155631	3.4627042	3.0779867	2.8695168	2.6667016	1.6127403	3.6789317	2.8410997	2.6735997	2.3668497	2.5163181	4.2649153	0.5706488	1.1136342	0.5586935	1.2581199	2.5762556	-0.5095674	-0.4622747	-0.4739252	2.6338191	2.7331772	0.5687255	0.6825458	0.7097570	3.948893	3.7824776	0.1221906	0.1164763	0.2264093	3.3014235	3.6377144	2.0085058	2.0714800	1.8988060	3.7266948	3.673672	0.4374900	1.752432	0.3717169	0.3818238	1.9495912	1.1822245	-0.4264249	1.733713	-0.4754826	-0.5280391	0.6391022	1.604538	1.3707459	0.8531207	0.8179795	0.5042350	1.891331	3.2942710	1.4763336	1.5068489	0.9277205	1.4310076	2.0294166	3.2295084	3.498641	2.4927595	2.6855316	2.7005033	2.8877723	3.5803597	4.011833	-0.2549299	-0.3366677	-0.2425476	2.4185290	2.6039116	0.0670853	0.2438334	0.0192902	2.5890875	3.6825535	0.5337199	1.726145	1.830035	0.9059107	-0.0810313	1.153540	2.665057	2.593839	2.381468	2.9708312	3.575979	2.067331	2.4290688	1.9784580	1.9055711	1.8701533	2.3277006	1.287699	-0.0170091	-0.0163280	-0.0732610	2.5352397	3.7047498	4.1133260	1.394961	2.350285	0.5799798	0.4024147	1.0056914	2.1257224	4.1480912	0.7853808	1.718001	0.2076823	1.1652540	2.349523	-0.0869793	-0.4098226	-0.1122777	3.3069775	3.7830482	-0.5757388	-0.6567806	-0.6812946	2.3128040	2.470543	1.2637514	0.6275493	1.8255117	3.0979283	2.9566851	1.7136360	1.7227242	1.7709732	3.7983873	3.9829596	-0.2913901	3.739290	-0.3788365	-0.3335062	2.1542265	3.7612965	3.447975	-0.1668886	-0.4147092	-0.2878433	0.8584269	3.2003706	3.664044	2.5303206	2.1850417	2.6772840	3.7956839	4.118933	3.5888238	3.6779687	1.4713571	1.5241871	1.6175816	2.0036302	3.4136062	4.128278	0.1555141	1.428682	1.1314962	1.2889318	0.1355244	2.6788592	1.5188159	1.1309737	0.8539886	0.7879840	0.8219442	1.064193	1.267083	-0.0785937	0.7627317	0.7770122	0.8738422	1.239219	1.184186	1.6136297	0.9976661	0.7754449	0.8809826	0.9668407	1.1796576	0.9796334	1.1382881	4.8011450	2.0311785	1.419548	0.8946460	1.0688004	1.2298934	2.0209033	2.2621074	1.1173897	2.6100352	2.7718248	2.5065875	3.393905	5.612808	1.3628956	1.3949401	1.5020452	1.930988	2.292533	1.7227179	2.2160976	1.8092726	4.190662	6.174631	0.7272041	0.7141424	0.6986427	0.8931734	1.0417272	0.8066186	0.7366084	0.7949501	1.233123	1.349806	1.3564264	1.2209342	1.495576	1.961265	2.320198	1.421063	1.407653	1.399468	1.509185	1.822664	0.8588924	0.8649878	0.8083876	1.3099526	1.594869	0.8913370	1.4017839	2.720830	1.1304512	0.8591185	1.7044646	2.3373423	3.2462547	1.4829400	1.4669178	1.9262110	1.9478061	1.8838915	4.0435818	6.369416	1.7090403	1.9220313	1.7492700	4.413835	8.439765	0.9220850	0.9499497	0.8715802	1.2087433	1.1794854	1.9728844	1.9328289	1.8816274	3.0580413	5.441521	1.9276042	1.7778313	1.7919378	2.363339	4.271376	2.275130	1.770743	1.822713	1.746408	2.039044	2.1857948	2.0565722	1.9137654	4.212954	5.174635	0.6185336	0.6185336	0.6185336	0.9435040	3.580204	1.0743735	1.693667	1.7305877	1.2527077	1.4651762	1.0565767	1.2423996	2.6429505	3.1070724	2.8413124	1.916923	1.785795	1.963947	1.550900	1.875834	1.604639	1.376452	1.637166	1.633358	1.730390	0.6185336	0.6185336	0.6185336	0.6185336	0.7950615	2.0116403	2.3252926	2.0562239	4.2702507	6.349133	0.6194299	0.6749853	0.6185336	0.9990868	1.365334	0.6415220	0.6185336	1.6037259	3.2609804	3.3720911	-0.2238852	1.9206871	1.7970374	1.424347	2.384286	2.419466	2.4783149	-0.3941232	2.3435192	2.3546650	4.3995537	6.777808	0.9926431	0.9783624	0.9720929	1.194837	-0.3800656	1.8399049	1.1798337	1.1028574	1.3111463	2.303653	2.297035	1.3615636	3.0414834	-0.8278037	1.741240	-0.8607138	-0.4145194	2.2407956	1.9300545	2.1766450	2.6932378	4.230463	5.4043483
IgG1_TT	1.4942539	0.9973524	1.379332	1.4170713	1.796847	1.928070	-0.0360037	-0.0288290	-0.0140251	0.8696624	1.6822231	1.3199179	1.1930065	1.1088045	1.0161686	1.6040350	1.5521572	1.5000565	1.3901590	1.5980812	1.9856687	1.1547810	1.4038720	1.1013947	1.5671517	1.8910605	0.5880250	0.6965240	0.7088144	1.2108817	1.1766362	1.4034189	1.4765204	1.4700421	2.160048	1.9214081	0.5930236	0.5758680	0.6565276	1.7216185	1.7512511	0.4642361	0.5210018	0.4467806	1.7937603	1.714260	1.0216353	1.217418	0.9688687	0.9824653	1.5203968	1.4383708	0.8694138	1.219905	0.8058099	0.7870546	1.6150368	1.269713	1.5098782	1.1033547	1.1304278	0.9982613	1.699897	1.8525056	1.1550217	1.1358865	1.3819554	1.1000155	1.4653198	1.7304163	1.814931	1.0635914	1.1017060	1.1314832	1.7195908	1.9195491	1.920492	1.3685293	1.2814775	1.3553658	1.8143336	1.8979064	1.3870732	1.4858921	1.3220497	1.7977298	1.8494703	0.8648448	1.273467	1.243235	1.0060086	0.6224056	1.761833	1.122304	1.140437	1.038616	1.3817739	1.674813	1.184950	1.0800612	0.9513215	0.9583064	1.0901308	1.2242128	1.796419	0.6105512	0.6130345	0.5188919	0.9312356	1.0707973	1.5553381	1.808255	1.916254	1.3939986	1.2565924	1.5771796	1.9345008	2.0869477	1.2083483	1.266388	1.0057331	1.3481829	1.700810	1.2990612	1.0670681	1.2775921	1.8736038	1.8801955	1.0300447	0.9004937	0.9077404	1.8225842	1.827339	0.4983790	0.4345671	0.6710703	1.2743881	1.2314500	0.7593167	0.7942923	0.7942923	1.7944521	1.7833191	1.0023961	1.612163	0.9383864	0.9866677	1.6926585	1.8094933	1.538321	0.8573599	0.7265908	0.7662003	1.3665397	1.5853875	1.584723	0.4339995	0.3444166	0.5158720	1.4445345	1.854678	1.7826653	1.7999296	0.3297649	0.3816226	0.3880640	1.0999974	1.5073665	1.866985	0.8927283	1.280061	0.8701404	1.2501582	0.8712884	1.5097876	1.0545733	0.8577139	0.4765486	0.3163314	0.2909739	1.531316	2.122213	0.7685733	1.3427407	1.0794206	1.1575112	2.176220	2.229325	1.8958784	1.4807866	1.2388412	1.3338190	1.7900953	2.0782950	1.1173962	1.2288632	1.9645804	1.5578738	1.251380	1.0421468	1.0333048	1.2597967	1.5264624	1.1482767	0.9772793	0.7114500	0.7488093	0.7077327	1.283893	1.743913	1.1687752	1.2250928	1.1904154	1.696212	1.989218	0.7763972	0.9165673	0.7638379	1.870488	1.898979	1.2699605	1.0262628	1.1270556	1.4127328	1.6278603	1.1227275	0.8315541	0.9320017	1.839828	1.933425	0.9609443	0.9484646	1.316720	1.775996	1.862371	1.125813	1.252521	1.172360	1.695203	1.796713	1.5642996	1.5169035	1.5838156	1.8925402	1.990280	0.4346812	0.8648299	1.458541	0.7371660	0.3856124	0.2509917	0.8825138	1.5242851	0.7488756	0.2704812	1.1896400	1.1808512	1.1841437	1.7488334	2.139764	1.3497244	1.4064934	1.3613278	2.251444	2.338854	1.1996503	1.2391602	1.3992181	1.6518906	1.7262107	1.5159955	1.4720513	1.5046841	1.7817318	1.979494	0.8326962	0.8105515	0.8352453	1.526723	1.896173	1.197218	1.336763	1.262193	1.298056	1.130167	1.2766974	1.3002493	1.2689176	1.797443	1.886446	0.3938113	0.5003926	0.5004191	1.7199970	2.345598	0.6668553	1.111422	1.6183867	0.9285291	0.7218187	0.6234024	0.7532435	1.7114131	1.6944727	1.7867688	1.080213	1.114651	1.054211	1.174254	1.125193	1.054653	1.160714	1.165550	1.162177	1.018488	0.2165666	0.2165666	0.2165666	0.9112302	0.9811161	0.2165666	0.5527995	0.3738630	1.2257168	1.575465	0.5290218	0.4379737	0.4349201	1.6411953	1.797084	0.2165666	0.2165666	0.6529365	1.2964603	1.2788826	0.5391438	0.9100168	0.8970327	1.337723	1.648465	1.664131	0.9555833	0.4918818	0.9134181	0.9223928	1.9183969	2.134241	1.3880448	1.4130040	1.4301038	1.551873	0.4434526	1.8971338	0.2492871	0.2555269	0.5511081	1.171053	1.436763	1.1476932	1.5000565	1.3814640	1.198906	1.1853307	1.7992657	1.9187987	0.3005357	0.3416668	0.4411048	1.999717	1.8982233
IgG1_DT	2.3434477	1.3191510	1.967139	2.0217981	1.448302	2.190173	0.1001077	0.1041319	0.1133316	0.1135075	0.8364962	2.1334100	2.0159018	1.9785639	1.3979725	2.2193623	1.7488580	1.6337922	1.5996521	1.3674440	2.0013216	0.7906973	1.0359293	0.7867754	0.8694681	1.5003203	0.8892404	0.9939868	1.0110826	1.7178111	1.7381737	1.9842565	2.1171763	2.0442576	2.504453	2.3072543	0.7548273	0.7575290	0.7926797	1.8112893	1.8893019	0.3678322	0.4097090	0.3476255	1.3384579	1.400485	1.0342597	1.328034	0.9687145	0.9999533	1.7721647	1.5257286	0.8041058	1.402812	0.7255585	0.6824434	1.2249610	1.505265	1.6530662	0.7231663	0.7358026	0.6960646	1.658798	2.2747209	0.3562090	0.3470063	1.4233212	0.3244919	0.9315924	1.6593450	2.216804	1.6687917	1.7280042	1.7732774	2.1332290	2.2117126	2.473230	0.8472022	0.7516222	0.8315353	2.1297450	2.1786361	1.7390544	1.9236618	1.6315119	2.3768063	2.4142923	1.0268356	1.429192	1.373184	1.1908616	0.5837100	1.997321	1.390064	1.385596	1.244956	1.4559493	1.543485	1.293818	0.8165237	0.6980986	0.6838790	1.4334286	1.6656981	2.001879	1.5392004	1.5568001	1.4977485	1.5682051	1.7064842	2.3852799	2.079356	2.189822	2.1406221	1.9774098	2.1734579	2.2627900	2.3363862	1.2771535	1.421295	0.8592747	1.4955558	1.941961	1.7958483	1.1765943	1.6837072	1.9039558	1.8382846	0.3617330	0.2818871	0.2900683	1.2010578	1.340467	0.5050052	0.3744709	0.7071602	1.2340922	1.0764756	1.7448937	1.7397780	1.7548147	2.0497353	1.9618663	1.9965385	2.212156	1.8250635	1.8674349	2.2089415	2.3059802	2.116932	1.3572986	1.1692368	1.2480372	2.0017216	2.1219854	2.187739	0.8031633	0.6984232	0.8996357	2.3154690	2.664523	2.1147003	2.0957005	0.1778492	0.2135290	0.2190579	1.2919990	2.0239851	2.650579	0.4345309	1.388917	0.7777870	1.2997699	0.4035944	1.7299289	0.8949730	0.6012059	0.8630259	0.6756496	0.6381918	1.833550	2.328090	0.3361378	1.5570377	1.2701205	1.3622912	1.955028	1.946661	2.3671708	2.1263199	1.7419860	1.8987978	2.2079556	2.4236853	1.2326144	1.3196261	2.5688767	1.8779830	1.202093	1.1246195	0.8615471	1.3958858	1.9763533	1.2351724	0.7957789	0.1714251	0.1714251	0.1714251	1.167663	1.931214	0.6163039	0.6394550	0.6413625	1.774551	2.374224	0.4251376	0.5704171	0.5057762	2.150196	2.380709	1.5658386	1.2562906	1.3728262	2.3479023	2.5112171	1.9329174	1.5345370	1.6966811	2.037921	2.103732	1.1487557	1.1902021	1.527497	2.070333	2.112516	1.638462	1.673536	1.692525	2.403055	2.516512	1.2624528	1.1667271	1.3043329	2.4672186	2.659017	0.8961436	1.3891226	1.875035	1.1556610	0.8176294	0.1714251	0.3103869	0.6960647	0.1714251	0.1714251	1.3208454	1.3178107	1.3110474	2.0235713	2.727251	1.2735895	1.3898218	1.3121313	2.571610	2.796878	0.1714251	0.1875095	0.4906844	1.2383685	1.7024738	2.0599887	1.9564159	2.0019810	2.3348968	2.638115	2.3527586	2.3529756	2.3282638	2.340099	2.480480	1.368178	1.674228	1.659680	1.761271	1.256643	0.8895030	0.9223220	0.8994310	1.797250	1.798638	0.2558956	0.3200597	0.2853764	1.5517485	2.742598	1.7382962	1.752863	1.6372379	1.6625133	1.7310561	1.5599735	1.5400740	2.2492597	2.3376586	2.4358556	1.197434	1.104493	1.175006	1.355198	1.347442	1.331050	1.463825	1.504740	1.438003	1.132337	0.1714251	0.1714251	0.1714251	0.2711191	0.8125680	0.3945731	0.6017621	0.5108486	1.7072039	1.865880	0.9396385	0.8292590	0.8143019	1.8856241	1.969471	0.6179720	0.6188824	0.8676913	1.1758953	1.0318731	0.9100775	1.2339464	1.2079773	1.509852	1.713616	1.604363	0.1714251	0.8241495	0.1714251	0.1714251	0.5716873	1.528034	0.6122286	0.6698028	0.6704965	1.190528	0.8021167	1.9447590	1.5206902	1.4573499	1.7250178	2.069552	2.141303	1.1866345	1.3459609	0.8795636	1.436581	0.6756544	2.4593163	2.4864342	0.1120417	0.1182029	0.1362427	2.319580	2.3009577
IgG1_OVA	0.8001983	0.5592840	30.350331	39.2089620	19.495070	46.377278	3.0450177	3.6050944	4.9479852	0.9771073	5.3863573	0.3327360	0.3227367	0.5148654	0.3227367	0.3605089	0.3227367	0.3227367	0.3913803	0.3227367	0.4160771	0.9242778	1.5706639	1.1940341	0.4660814	1.3422165	14.5366120	15.7529416	16.5370736	12.8016458	11.5854607	0.3678162	0.4332633	0.3939950	0.603426	0.5118001	0.4332633	0.4463527	0.4398081	0.5510683	0.6557837	1.9516377	2.7500932	1.5982230	3.2605810	3.240947	1.5262311	4.049869	1.2317190	1.3037107	0.7709038	28.2506108	1.0550115	4.213673	0.7735887	0.6819625	0.7709038	3.096408	33.0687699	1.8076539	1.8207433	1.5524101	1.053313	2.5406623	0.4463527	0.4201739	20.7148366	0.3809056	0.3227367	0.7277756	15.709687	0.3806605	0.4461076	0.4853759	0.4330182	0.4591970	21.319443	0.6555386	0.5246444	0.5900915	0.6387346	0.5461206	0.4199288	0.4461076	0.3547187	0.4782038	0.4288096	9.5039959	3.922057	4.546617	14.9033875	4.6215286	5.038682	1.925214	1.912124	1.737753	1.9723749	4.244503	3.718976	1.1005793	0.7995224	0.8486595	0.6634316	0.7004771	5.312936	0.3227367	0.3227367	0.3227367	0.3227367	0.3227367	0.8999274	5.624589	4.116188	0.3227367	0.3227367	0.3227367	0.4096987	0.3712006	19.3637109	4.176695	12.7755284	29.4631085	10.502679	0.4738626	0.3227367	0.4610300	0.7048526	0.6150231	0.4866955	0.3405662	0.4161153	0.4738626	0.512361	10.5475931	7.7818198	18.1574311	13.2232270	9.8417912	4.6666851	4.5594873	4.9713531	4.7908092	3.0192220	20.4924874	3.673641	18.5121465	21.5870347	19.0551934	23.2503572	2.526757	2.7427640	1.6764264	2.0487983	2.6279542	2.3465314	2.514291	5.2534528	3.0925679	5.6088986	0.6443717	2.570389	6.4435244	3.8583610	2.1277864	2.7484062	3.4254458	2.7457592	1.0834012	2.707516	8.9156475	4.315177	-0.6993852	-1.3439741	7.9245901	-1.3243222	-1.3714871	-1.4029303	-1.6996770	-1.6996770	-1.6996770	-1.699677	-1.670199	5.2568388	-0.7662020	-1.5699735	-1.4206171	-1.184792	-1.302704	3.1438303	0.1083164	-1.3538003	-0.9135928	-0.0823088	0.1947861	7.6409693	5.4556551	0.6132064	6.0845222	5.848697	5.1412210	0.5563846	0.0120215	-0.0272827	0.4777763	-0.1844997	-1.6996770	-1.6996770	-1.6996770	-1.699677	-1.685921	-1.6996770	-0.4187732	-1.3186326	-1.682404	-1.487848	13.5994878	14.1772599	14.3895020	14.861153	13.255576	38.6952291	22.6610742	29.0204949	32.4674745	30.8992372	-1.6741295	-1.6996770	-1.6996770	-1.691816	-1.664303	16.1735005	17.4548173	17.407652	19.139002	18.975892	2.375757	4.042255	1.974854	2.845442	2.562452	2.1360009	1.4815857	2.2087138	1.8274627	2.725564	18.1194711	15.3406644	12.823229	11.8091812	16.0756536	-1.3341479	-1.3203917	-1.2909131	-1.2850175	-1.4147215	6.1391559	6.0015907	5.2351589	3.4605734	3.662990	-1.6981044	-1.6391482	-1.6981044	-1.605740	-1.470140	-1.4957085	-1.5232215	-1.4799867	-1.4367518	-1.3797612	-1.6996770	-1.6996770	-1.6996770	-1.6996770	-1.639148	-1.5762615	-1.6470089	-1.6273570	-1.603775	-1.550714	3.741982	3.665218	3.658962	3.197500	4.514416	5.6914802	5.4301071	4.7953439	3.734130	4.695118	0.3244896	1.2206259	1.8534236	4.1841636	6.660329	4.7049446	5.003656	3.7498519	3.2428277	5.6580715	-0.7740631	-0.0371089	1.6156332	0.5740716	-0.1864648	4.088694	4.249992	4.332330	3.854132	4.718963	5.047263	4.307703	4.194562	4.268793	4.570009	-0.8214345	3.1755974	0.9570811	0.1592054	1.4228358	6.4382601	7.7824645	5.3416729	8.4486704	7.585943	10.1422691	8.6939087	8.1790237	6.2118478	8.320519	1.6957936	1.3990469	1.3047168	0.8920226	0.5913453	0.6381388	-1.3227696	-1.1832399	-1.208787	-1.285431	-1.273640	0.0137901	0.5633421	-0.4637561	-0.4598255	0.2199411	1.568076	13.5715623	14.8646703	15.6802335	15.662547	0.5508759	16.4722123	18.5926747	16.0752397	15.5367723	16.861325	15.363835	0.5134773	0.7732458	0.3227367	4.014214	0.3227367	0.3227367	0.3830800	0.3327360	0.3956661	0.4334240	0.534112	0.4963541
IgG2_PT	2.7249818	2.7249818	2.724982	2.7249818	2.724982	2.724982	2.7249818	2.7249818	2.7249818	2.7249818	2.7249818	8.0937715	7.2524548	6.8258176	7.0442362	7.3354611	2.7249818	2.7249818	2.7249818	2.7249818	2.8942828	3.4116640	3.5495386	2.8214767	4.0591822	3.7679572	2.7249818	2.7249818	2.7249818	4.5324225	5.0845661	2.9957812	3.0330808	2.8465822	3.144980	3.1449800	2.9211817	2.9211817	2.9211817	3.3687785	3.2941790	3.1449800	4.2639718	3.7417758	4.0401735	6.651154	2.7249818	6.256094	2.7249818	2.7249818	2.7249818	2.7249818	2.7249818	6.251697	2.7249818	2.7249818	2.7249818	5.544154	2.7249818	2.7249818	2.7249818	2.7249818	2.995781	3.7417758	2.7249818	2.7249818	2.7249818	2.7249818	2.7249818	3.2195795	2.724982	2.7952187	2.7249818	2.7249818	3.1924303	9.0513005	2.724982	2.7249818	2.7249818	2.7249818	2.7249818	2.7249818	5.1784878	4.7812762	5.0765009	8.2689548	26.0730224	2.9938245	6.269362	6.781812	2.9938245	2.7249818	5.742397	33.579114	31.990266	30.616128	29.2245460	32.417001	6.188257	5.1288366	4.9798822	3.7667766	4.9946432	6.3862257	5.789870	2.7249818	2.7249818	2.7249818	2.7249818	2.7249818	2.9652631	5.837342	7.973599	2.9494390	3.1024055	2.7249818	5.5498705	8.0738187	4.4791045	6.469099	5.7410789	5.0909710	4.326138	2.7249818	2.7249818	2.7249818	2.7249818	2.7964725	3.0259223	3.1788888	2.7249818	3.0259223	2.949439	4.2496548	5.1292124	4.6703129	3.7907553	4.7850380	2.7249818	2.7249818	2.7249818	2.7249818	2.7249818	2.7249818	7.403931	2.7249818	2.7249818	2.7249818	2.7249818	5.837342	2.7249818	2.7249818	2.7249818	2.7249818	5.7064223	5.505035	82.5685287	77.2763839	71.4957290	2.7249818	7.285250	112.4533172	135.0982070	8.2341866	10.2696290	7.8678074	8.3092437	9.1768508	7.498876	2.7249818	6.211989	-3.1460652	-3.1460652	2.7249818	-3.1460652	-3.1460652	-3.1460652	7.7989297	-1.0159883	-1.0159883	10.158650	19.936459	2.7249818	45.0793967	26.9206061	34.6031737	51.365129	56.254034	2.7249818	3.1745012	1.0792565	0.3808417	4.5713310	7.3649907	-3.1460652	-3.1460652	2.7991099	-3.1460652	-3.146065	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.146065	2.883367	-3.1460652	-3.1460652	-3.1460652	-3.146065	-2.447651	34.6612449	32.9152083	30.1215491	34.312036	44.089845	-1.7144036	-0.3175735	-1.0159883	8.7618203	8.7618203	36.0000014	23.4285331	25.5237784	20.634873	34.603174	-3.1460652	-3.1460652	-3.146065	-2.243354	1.248720	-3.146065	-3.146065	-3.146065	-3.146065	-2.447651	-3.1460652	1.7428384	-1.0508208	0.3460088	1.044424	-3.1460652	-3.1460652	-3.146065	-3.1460652	-3.1460652	21.5027528	24.9948287	17.3122621	21.1535459	22.2011666	-3.1460652	-3.1460652	-3.1460652	1.1097288	6.347841	8.7922931	2.5065589	0.4113140	6.697048	15.776442	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.146065	9.4907079	10.1891227	7.3954630	10.887538	15.776442	6.001921	6.113429	6.054778	5.992987	6.693699	27.3278861	23.1373992	25.2326446	28.724718	39.200941	-1.7144036	-3.1112332	-1.7144036	-0.3175735	10.857065	-3.1460652	-3.146065	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	6.385632	6.428774	6.647703	6.333085	7.050898	6.937848	6.593685	6.570011	6.712891	6.829513	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-3.1460652	-2.703953	-3.1460652	-3.1460652	-3.1460652	-1.0508208	-0.352406	-3.1460652	-3.1460652	-3.1460652	-2.2433543	15.9154334	2.7249818	9.6296992	14.5186038	8.931284	22.201167	24.296411	22.0621762	2.7249818	20.6653466	23.4590049	21.3637605	24.157419	-3.1460652	-3.1460652	-2.4476514	1.393631	2.7249818	0.6952162	6.8360395	8.9312844	8.2328696	12.423358	28.486902	2.7249818	2.7249818	2.7249818	6.198991	2.7249818	2.7249818	2.7249818	2.7249818	2.7249818	2.7249818	3.265348	3.1190324

# knitr::kable(head(results$rnaseq), "html", align = "lccrr", booktabs=TRUE, border_left = T, 
#              border_right = T, caption = "RNA seq")  %>% 
#   kable_styling("striped", full_width = T) %>% 
#   scroll_box(width = "100%", height = "400px")
# 
# knitr::kable(head(results$cytof), "html", align = "lccrr", booktabs=TRUE, border_left = T, 
#              border_right = T, caption = "Cell Frequency")  %>% 
#   kable_styling("striped", full_width = T) %>% 
#   scroll_box(width = "100%", height = "400px")
# 
# olink <- head(results$olink)
# knitr::kable(, "html", align = "lccrr", booktabs=TRUE, border_left = T, 
#              border_right = T, caption = "Olink")  %>% 
#   kable_styling("striped", full_width = T) %>% 
#   scroll_box(width = "100%", height = "400px")

Imputation using MOFA for Batch Corrected Data

2023-09-07

Load libraries

Load data and Generate Mofa object

Plot multiomic missing values

Setting data Options

Setting model Options

Setting training Options

Training Model

Impute Data

Add meta data to Mofa and Imputed objects

Mofa object

Imputed data

Results for Actual Data

Results for Actual Data

Results for Imputed Data