5th MT Spectrum of Fractures

Author

Kingery MT

Published

September 17, 2023

Results

Anatomic distribution of fractures

A total of 2,459 5th metatarsal fractures in 2,453 patients presented to our institution. Among all 5th metatarsal fractures, 955 were Zone 1 metatarsal base fractures, representing the most common type of 5th metatarsal fracture (38.8%). Similar numbers of Zone 2 metatarsal base fractures and shaft fractures were treated (26.2% and 24.5% respectively). Zone 3 base fractures, or true Jones fractures, represented a relatively smaller proportion of the 5th metatarsal fractures seen with 6.9%. 3.3% of 5th metatarsal fractures were of the metatarsal neck, while isolated 5th metatarsal head fractures were relatively uncommon (0.2%).

Figure 1: Distribution of 5th metatarsal fractures.

Table 1: Demographics of patients with 5th metatarsal fractures.
Characteristic Overall, N = 2,4591 Type of 5th Metatarsal Fracture p-value2
Zone 1, N = 9551 Zone 2, N = 6451 Zone 3, N = 1701 Shaft, N = 6021 Neck, N = 821 Head, N = 51
Age (years) 49.5 +/- 18.5 45.7 +/- 19.0 53.0 +/- 17.1 46.1 +/- 18.6 51.9 +/- 17.3 55.1 +/- 22.1 53.2 +/- 19.6 <0.001
Sex 0.002
    Female 1,763 (72.2%) 647 (68.4%) 480 (74.4%) 112 (66.3%) 456 (76.5%) 65 (79.3%) 3 (60.0%)
    Male 680 (27.8%) 299 (31.6%) 165 (25.6%) 57 (33.7%) 140 (23.5%) 17 (20.7%) 2 (40.0%)
BMI 26.8 +/- 5.9 26.5 +/- 5.7 27.2 +/- 6.0 28.2 +/- 6.7 26.4 +/- 5.6 27.1 +/- 6.0 29.9 +/- 9.4 0.005
Race 0.029
    Asian 148 (6.1%) 60 (6.3%) 42 (6.6%) 15 (8.9%) 26 (4.4%) 5 (6.1%) 0 (0.0%)
    Black 158 (6.5%) 61 (6.4%) 37 (5.8%) 18 (10.7%) 40 (6.7%) 2 (2.4%) 0 (0.0%)
    Native American 6 (0.2%) 2 (0.2%) 1 (0.2%) 0 (0.0%) 2 (0.3%) 1 (1.2%) 0 (0.0%)
    Other 292 (12.0%) 119 (12.6%) 61 (9.5%) 24 (14.2%) 71 (11.9%) 14 (17.1%) 3 (60.0%)
    Pacific Islander 2 (0.1%) 0 (0.0%) 1 (0.2%) 1 (0.6%) 0 (0.0%) 0 (0.0%) 0 (0.0%)
    Unknown 262 (10.8%) 109 (11.5%) 70 (11.0%) 19 (11.2%) 55 (9.2%) 9 (11.0%) 0 (0.0%)
    White 1,569 (64.4%) 595 (62.9%) 427 (66.8%) 92 (54.4%) 402 (67.4%) 51 (62.2%) 2 (40.0%)
Smoking status 0.013
    Daily 203 (8.5%) 79 (8.5%) 52 (8.2%) 15 (9.1%) 53 (9.0%) 4 (4.9%) 0 (0.0%)
    Former 459 (19.1%) 152 (16.4%) 142 (22.5%) 26 (15.8%) 114 (19.4%) 21 (25.6%) 4 (80.0%)
    Never 1,739 (72.4%) 698 (75.1%) 438 (69.3%) 124 (75.2%) 421 (71.6%) 57 (69.5%) 1 (20.0%)
Charlson Comorbidity Index 0.4 +/- 1.0 0.3 +/- 0.9 0.5 +/- 1.1 0.4 +/- 0.9 0.4 +/- 1.1 0.9 +/- 2.1 1.2 +/- 1.3 <0.001
1 Mean +/- SD; n (%)
2 Kruskal-Wallis rank sum test; Fisher’s Exact Test for Count Data with simulated p-value (based on 2000 replicates)

Among all patients presenting with 5th metatarsal fractures, the mean age was 49.5 +/- 18.5 years. The majority of patients were female (71.7%). Although there were statistically significant differences in baseline demographic characteristics between groups, the small differences are unlikely to be clinically relevant (Table 1).

1145 patients (46.6%) did not meet inclusion criteria because they did not continue to follow up until the point of clinical and radiographic healing or until 6 months from the time of injury. Furthermore, only 2 patients with isolated metatarsal head fractures met the minimum follow up time. Given the low sample size for this group, isolated head fractures were not included in the analysis. Therefore, a total of 1314 patients with 5th metatarsal fractures were included in the subsequent analysis. The mean age of the overall cohort was 49.6 +/- 18.0 years and the mean BMI was 26.7 +/- 5.9.

Among the included patients, 80 patients (6.1%) were initially treated nonoperatively and 1234 patients (93.9%) were treated operatively.

Overall treatment

Table 2: Summary of treatment strategies for all 5th metatarsal fractures
Characteristic Overall1 Type of 5th Metatarsal Fracture p-value2
Zone 11 Zone 21 Zone 31 Shaft1 Neck1
Nonoperative
Treated with splint/cast 332 (27.3%) 113 (24.9%) 115 (34.1%) 24 (31.6%) 76 (24.8%) 4 (8.9%) <0.001
Duration of splint/cast (weeks) 1.9 +/- 3.4 2.3 +/- 5.3 1.7 +/- 2.0 1.5 +/- 1.8 1.6 +/- 1.8 2.0 +/- 1.5 0.944
Treated with CAM boot 954 (78.4%) 360 (79.5%) 270 (80.1%) 64 (84.2%) 229 (74.8%) 31 (68.9%) 0.130
Duration of CAM boot (weeks) 6.8 +/- 4.5 6.5 +/- 4.9 6.8 +/- 4.8 8.2 +/- 4.4 6.9 +/- 3.6 5.9 +/- 3.0 0.002
Treated with hard sole shoe 431 (35.4%) 142 (31.3%) 126 (37.4%) 22 (28.9%) 123 (40.2%) 18 (40.0%) 0.069
Duration of hard sole shoe (weeks) 4.8 +/- 4.2 4.9 +/- 5.3 4.6 +/- 3.4 4.1 +/- 4.1 5.0 +/- 3.5 5.2 +/- 4.2 0.515
Total duration of immobilization (weeks) 7.6 +/- 5.4 7.3 +/- 6.7 7.8 +/- 4.9 8.6 +/- 4.5 7.6 +/- 3.7 6.7 +/- 3.2 0.001
Operative
Type of Fixation Construct <0.001
    IM Screw 53 (54.6%) 6 (42.9%) 18 (85.7%) 24 (96.0%) 4 (11.1%) 1 (100.0%)
    K-wires 9 (9.3%) 2 (14.3%) 0 (0.0%) 0 (0.0%) 7 (19.4%) 0 (0.0%)
    ORIF 35 (36.1%) 6 (42.9%) 3 (14.3%) 1 (4.0%) 25 (69.4%) 0 (0.0%)
1 n (%); Mean +/- SD
2 Pearson’s Chi-squared test; Kruskal-Wallis rank sum test

Patients treated nonoperatively

Overall, patients treated nonoperatively were managed with some form of foot immobilization or support (cast, splint, CAM boot, or hard sole shoe) for an average of 7.7 +/- 5.5 weeks (Table 2). Overall, 27.7% of patients were treated in a splint or cast. 78.7% of patients were treated in CAM boot or another type of walking boot at some point during their treatment. 21.6% of patients were first treated in a splint or cast and then transitioned to a CAM boot, while 57.1% of patients were immediately placed in a CAM boot upon presentation. Likewise, the weightbearing status at the initial office presentation varied considerably. 25.3% of patients were made non-weightbearing, while 7.1% were made partial weightbearing and 56.0% were allowed to immediately bear weight as tolerated.

Table 3: Immediate versus delayed weightbearing for fractures treated nonoperatively
Characteristic Overall, N = 1,2171 Type of 5th Metatarsal Fracture p-value2
Zone 1, N = 4531 Zone 2, N = 3371 Zone 3, N = 761 Shaft, N = 3061 Neck, N = 451
Immediate Versus Delayed Weightbearing <0.001
    Delayed 390 (36.3%) 106 (26.1%) 118 (39.7%) 49 (72.1%) 109 (40.5%) 8 (23.5%)
    Immediate 684 (63.7%) 300 (73.9%) 179 (60.3%) 19 (27.9%) 160 (59.5%) 26 (76.5%)
1 n (%)
2 Pearson’s Chi-squared test

    Welch Two Sample t-test

data:  duration_clinical_healed by immediate_wb
t = 2.108, df = 827.68, p-value = 0.03533
alternative hypothesis: true difference in means between group Delayed and group Immediate is not equal to 0
95 percent confidence interval:
 0.08935874 2.50623103
sample estimates:
  mean in group Delayed mean in group Immediate 
              10.877778                9.579983 

    Welch Two Sample t-test

data:  duration_rad_healed by immediate_wb
t = -0.086515, df = 400.96, p-value = 0.9311
alternative hypothesis: true difference in means between group Delayed and group Immediate is not equal to 0
95 percent confidence interval:
 -3.371049  3.086849
sample estimates:
  mean in group Delayed mean in group Immediate 
               18.68429                18.82639 

Overall, patients who were allowed to bear weight immediately demonstrated slightly faster time to clinical healing (9.6 +/- 8.8 weeks versus 10.9 +/- 10.9 weeks, p = 0.035). However, there was no difference in time to radiographic healing between those who were allowed to bear weight immediately and those who had a period of restricted weightbearing (18.8 +/- 18.6 weeks versus 18.7 +/- 14.4 weeks, p = 0.931).

Table 4: Nonop Outcomes
Characteristic Overall, N = 1,2171 Type of 5th Metatarsal Fracture p-value2
Zone 1, N = 4531 Zone 2, N = 3371 Zone 3, N = 761 Shaft, N = 3061 Neck, N = 451
Time to clinical healing (weeks) 9.9 +/- 8.7 9.7 +/- 8.4 9.9 +/- 8.3 10.4 +/- 8.8 9.9 +/- 9.1 10.0 +/- 11.9 0.245
Time to radiographic healing (weeks) 17.9 +/- 15.6 18.7 +/- 22.2 18.7 +/- 12.0 19.7 +/- 11.2 16.1 +/- 8.5 13.0 +/- 5.3 0.088
1 Mean +/- SD
2 Kruskal-Wallis rank sum test
Table 5: Operative Outcomes
Characteristic Overall, N = 971 Type of 5th Metatarsal Fracture p-value2
Zone 1, N = 141 Zone 2, N = 211 Zone 3, N = 251 Shaft, N = 361 Neck, N = 11
Time to clinical healing (weeks) 12.3 +/- 15.6 9.8 +/- 8.3 15.5 +/- 15.0 11.0 +/- 25.1 11.9 +/- 9.6 23.1 +/- NA 0.502
Time to radiographic healing (weeks) 21.5 +/- 19.7 20.4 +/- 11.0 18.5 +/- 16.6 21.3 +/- 25.9 24.6 +/- 18.3 23.1 +/- NA 0.328
1 Mean +/- SD
2 Kruskal-Wallis rank sum test

Figure 2: Clinical healing.