UNSUPERVISED MACHINE LEARNING TOOLS FOR MONITORING BIOBASED AND BIOTECHNOLOGY PRODUCT : MONITORING BIOREACTOR USING PCA FOR PENICILLIN PRODUCTION
affandry taufik
2023-04-26
knitr::include_graphics("Bioreactor.png")
1 Introduction
Here, some variables of a Bioreactor to Produce Penicillin provided from a Pharmacy company. In Bioeactor, there are a lot of data produced by many sensors. But, not all sensors contribute for Bioreactor performance, furthermore, the data taken every second which means need a lot of storage to keep all data. Creating a model from all variables will spend a lot of time and long computation time. Hence, dimensionality reduction is the objective in this case.
2 Data Import
Import the related library for dimensionality reduction.
library(dplyr)##
## Attaching package: 'dplyr'## The following objects are masked from 'package:stats':
##
## filter, lag## The following objects are masked from 'package:base':
##
## intersect, setdiff, setequal, unionlibrary(GGally)## Loading required package: ggplot2## Registered S3 method overwritten by 'GGally':
## method from
## +.gg ggplot2library(factoextra)## Welcome! Want to learn more? See two factoextra-related books at https://goo.gl/ve3WBalibrary(FactoMineR)Then import the dataset into a dataframe.
Penicillin <- read.csv("Penicillin.csv")
head(Penicillin,10)## X Time..h. Aeration.rate.Fg.L.h. Agitator.RPM.RPM.RPM.
## 1 1 0.2 30 100
## 2 2 0.4 30 100
## 3 3 0.6 30 100
## 4 4 0.8 30 100
## 5 5 1.0 30 100
## 6 6 1.2 30 100
## 7 7 1.4 30 100
## 8 8 1.6 30 100
## 9 9 1.8 30 100
## 10 10 2.0 30 100
## Sugar.feed.rate.Fs.L.h. Acid.flow.rate.Fa.L.h. Base.flow.rate.Fb.L.h.
## 1 8 0.0000 30.1180
## 2 8 0.0000 51.2210
## 3 8 0.0000 54.3020
## 4 8 0.0000 37.8160
## 5 8 0.5181 18.9080
## 6 8 1.0387 9.4541
## 7 8 1.5604 4.7270
## 8 8 2.0823 2.3635
## 9 8 0.0000 0.0000
## 10 8 0.0000 0.0000
## Heating.cooling.water.flow.rate.Fc.L.h. Heating.water.flow.rate.Fh.L.h.
## 1 9.83350 1e-04
## 2 18.15500 1e-04
## 3 9.59820 1e-04
## 4 4.33950 1e-04
## 5 1.10450 1e-04
## 6 0.00010 1e-04
## 7 0.00010 1e-04
## 8 0.00010 1e-04
## 9 0.00010 1e-04
## 10 0.51077 1e-04
## Water.for.injection.dilution.Fw.L.h. Air.head.pressure.pressure.bar.
## 1 0 0.6
## 2 0 0.6
## 3 0 0.6
## 4 0 0.6
## 5 0 0.6
## 6 0 0.6
## 7 0 0.6
## 8 0 0.6
## 9 0 0.6
## 10 0 0.6
## Dumped.broth.flow.Fremoved.L.h. Substrate.concentration.S.g.L.
## 1 0 0.95749
## 2 0 1.00460
## 3 0 1.04980
## 4 0 1.09420
## 5 0 1.13700
## 6 0 1.17820
## 7 0 1.21720
## 8 0 1.25440
## 9 0 1.28910
## 10 0 1.32180
## Dissolved.oxygen.concentration.DO2.mg.L. Penicillin.concentration.P.g.L.
## 1 14.711 1.0178e-25
## 2 14.699 1.0000e-03
## 3 14.686 9.9934e-04
## 4 14.661 9.9874e-04
## 5 14.633 9.9821e-04
## 6 14.621 9.9771e-04
## 7 14.604 9.9722e-04
## 8 14.583 9.9674e-04
## 9 14.547 9.9627e-04
## 10 14.529 9.9580e-04
## Vessel.Volume.V.L. Vessel.Weight.Wt.Kg. pH.pH.pH. Temperature.T.K.
## 1 58479 62574 6.4472 298.22
## 2 58487 62585 6.4932 298.17
## 3 58495 62598 6.5425 298.14
## 4 58499 62607 6.5753 298.11
## 5 58501 62613 6.5825 298.09
## 6 58500 62617 6.5717 298.08
## 7 58498 62620 6.5521 298.07
## 8 58497 62622 6.5287 298.06
## 9 58494 62624 6.5061 298.06
## 10 58491 62626 6.4844 298.05
## Generated.heat.Q.kJ. carbon.dioxide.percent.in.off.gas.CO2outgas...
## 1 1e-06 0.089514
## 2 1e-06 0.101760
## 3 1e-06 0.105800
## 4 1e-06 0.108190
## 5 1e-06 0.110300
## 6 1e-06 0.112420
## 7 1e-06 0.114630
## 8 1e-06 0.116940
## 9 1e-06 0.119360
## 10 1e-06 0.121890
## PAA.flow.Fpaa.PAA.flow..L.h..
## 1 5
## 2 5
## 3 5
## 4 5
## 5 5
## 6 5
## 7 5
## 8 5
## 9 5
## 10 5
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... Oil.flow.Foil.L.hr.
## 1 NA 22
## 2 NA 22
## 3 NA 22
## 4 NA 22
## 5 1488 22
## 6 NA 22
## 7 NA 22
## 8 NA 22
## 9 NA 22
## 10 NA 22
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1...
## 1 NA
## 2 NA
## 3 NA
## 4 NA
## 5 1667.8
## 6 NA
## 7 NA
## 8 NA
## 9 NA
## 10 NA
## Oxygen.Uptake.Rate.OUR..g.min...1...
## 1 0.4805100
## 2 0.0581470
## 3 -0.0415050
## 4 -0.0567370
## 5 -0.0499750
## 6 -0.0452670
## 7 -0.0393690
## 8 -0.0310330
## 9 -0.0160250
## 10 -0.0071831
## Oxygen.in.percent.in.off.gas.O2.O2......
## 1 0.19595
## 2 0.20390
## 3 0.20575
## 4 0.20602
## 5 0.20589
## 6 0.20580
## 7 0.20569
## 8 0.20553
## 9 0.20524
## 10 0.20507
## Offline.Penicillin.concentration.P_offline.P.g.L...1...
## 1 NA
## 2 NA
## 3 NA
## 4 NA
## 5 1.0178e-25
## 6 NA
## 7 NA
## 8 NA
## 9 NA
## 10 NA
## Offline.Biomass.concentratio.X_offline.X.g.L...1...
## 1 NA
## 2 NA
## 3 NA
## 4 NA
## 5 0.52808
## 6 NA
## 7 NA
## 8 NA
## 9 NA
## 10 NA
## Carbon.evolution.rate.CER.g.h. Ammonia.shots.NH3_shots.kgs.
## 1 0.034045 0
## 2 0.038702 0
## 3 0.040240 0
## 4 0.041149 0
## 5 0.041951 0
## 6 0.042758 0
## 7 0.043599 0
## 8 0.044478 0
## 9 0.045398 0
## 10 0.046361 0
## Viscosity.Viscosity_offline.centPoise. Fault.reference.Fault_ref.Fault.ref.
## 1 NA 0
## 2 NA 0
## 3 NA 0
## 4 NA 0
## 5 4.083 0
## 6 NA 0
## 7 NA 0
## 8 NA 0
## 9 NA 0
## 10 NA 0
## X0...Recipe.driven.1...Operator.controlled.Control_ref.Control.ref.
## 1 0
## 2 0
## 3 0
## 4 0
## 5 0
## 6 0
## 7 0
## 8 0
## 9 0
## 10 0
## X1..No.Raman.spec X1.Raman.spec.recorded X2.PAT.control.PAT_ref.PAT.ref.
## 1 1 1 1
## 2 1 1 1
## 3 1 1 1
## 4 1 1 1
## 5 1 1 1
## 6 1 1 1
## 7 1 1 1
## 8 1 1 1
## 9 1 1 1
## 10 1 1 1
## Batch.reference.Batch_ref.Batch.ref. Batch.ID Fault.flag
## 1 0 0 0
## 2 0 0 0
## 3 0 0 0
## 4 0 0 0
## 5 0 0 0
## 6 0 0 0
## 7 0 0 0
## 8 0 0 0
## 9 0 0 0
## 10 0 0 0As shown below, all variables categorized as double and integer. So, subset from non numeric variables are not required.
glimpse(Penicillin)## Rows: 200
## Columns: 40
## $ X <int> 1,…
## $ Time..h. <dbl> 0.…
## $ Aeration.rate.Fg.L.h. <int> 30…
## $ Agitator.RPM.RPM.RPM. <int> 10…
## $ Sugar.feed.rate.Fs.L.h. <int> 8,…
## $ Acid.flow.rate.Fa.L.h. <dbl> 0.…
## $ Base.flow.rate.Fb.L.h. <dbl> 30…
## $ Heating.cooling.water.flow.rate.Fc.L.h. <dbl> 9.…
## $ Heating.water.flow.rate.Fh.L.h. <dbl> 1e…
## $ Water.for.injection.dilution.Fw.L.h. <int> 0,…
## $ Air.head.pressure.pressure.bar. <dbl> 0.…
## $ Dumped.broth.flow.Fremoved.L.h. <int> 0,…
## $ Substrate.concentration.S.g.L. <dbl> 0.…
## $ Dissolved.oxygen.concentration.DO2.mg.L. <dbl> 14…
## $ Penicillin.concentration.P.g.L. <dbl> 1.…
## $ Vessel.Volume.V.L. <int> 58…
## $ Vessel.Weight.Wt.Kg. <int> 62…
## $ pH.pH.pH. <dbl> 6.…
## $ Temperature.T.K. <dbl> 29…
## $ Generated.heat.Q.kJ. <dbl> 0.…
## $ carbon.dioxide.percent.in.off.gas.CO2outgas... <dbl> 0.…
## $ PAA.flow.Fpaa.PAA.flow..L.h.. <int> 5,…
## $ PAA.concentration.offline.PAA_offline.PAA..g.L...1... <dbl> NA…
## $ Oil.flow.Foil.L.hr. <int> 22…
## $ NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... <dbl> NA…
## $ Oxygen.Uptake.Rate.OUR..g.min...1... <dbl> 0.…
## $ Oxygen.in.percent.in.off.gas.O2.O2...... <dbl> 0.…
## $ Offline.Penicillin.concentration.P_offline.P.g.L...1... <dbl> NA…
## $ Offline.Biomass.concentratio.X_offline.X.g.L...1... <dbl> NA…
## $ Carbon.evolution.rate.CER.g.h. <dbl> 0.…
## $ Ammonia.shots.NH3_shots.kgs. <int> 0,…
## $ Viscosity.Viscosity_offline.centPoise. <dbl> NA…
## $ Fault.reference.Fault_ref.Fault.ref. <int> 0,…
## $ X0...Recipe.driven.1...Operator.controlled.Control_ref.Control.ref. <int> 0,…
## $ X1..No.Raman.spec <int> 1,…
## $ X1.Raman.spec.recorded <int> 1,…
## $ X2.PAT.control.PAT_ref.PAT.ref. <int> 1,…
## $ Batch.reference.Batch_ref.Batch.ref. <int> 0,…
## $ Batch.ID <int> 0,…
## $ Fault.flag <int> 0,…As shown above, not all variables contain data, and some varaibles mostly contain NA. In this case, NA means no indication of sensors like no flow or etc., NA shall be replaced to 0. Some variables like “Fault.reference.Fault_ref.Fault.ref.”,“X0…Recipe.driven.1…Operator.controlled.Control_ref.Control.ref.”, and “Ammonia.shots.NH3_shots.kgs.” removed because entire row contain 0 value.
3 Data Wrangling
For some cell that contain NA, the NA value shall be replced into 0.
Penicillin <- Penicillin %>%
select(-c(X,
Fault.reference.Fault_ref.Fault.ref.,
X0...Recipe.driven.1...Operator.controlled.Control_ref.Control.ref.,
Ammonia.shots.NH3_shots.kgs.))
Penicillin <- replace(Penicillin, is.na(Penicillin), 0)glimpse(Penicillin)## Rows: 200
## Columns: 36
## $ Time..h. <dbl> 0.2, 0.4, 0.6,…
## $ Aeration.rate.Fg.L.h. <int> 30, 30, 30, 30…
## $ Agitator.RPM.RPM.RPM. <int> 100, 100, 100,…
## $ Sugar.feed.rate.Fs.L.h. <int> 8, 8, 8, 8, 8,…
## $ Acid.flow.rate.Fa.L.h. <dbl> 0.0000, 0.0000…
## $ Base.flow.rate.Fb.L.h. <dbl> 30.1180, 51.22…
## $ Heating.cooling.water.flow.rate.Fc.L.h. <dbl> 9.83350, 18.15…
## $ Heating.water.flow.rate.Fh.L.h. <dbl> 1e-04, 1e-04, …
## $ Water.for.injection.dilution.Fw.L.h. <int> 0, 0, 0, 0, 0,…
## $ Air.head.pressure.pressure.bar. <dbl> 0.6, 0.6, 0.6,…
## $ Dumped.broth.flow.Fremoved.L.h. <int> 0, 0, 0, 0, 0,…
## $ Substrate.concentration.S.g.L. <dbl> 0.95749, 1.004…
## $ Dissolved.oxygen.concentration.DO2.mg.L. <dbl> 14.711, 14.699…
## $ Penicillin.concentration.P.g.L. <dbl> 1.0178e-25, 1.…
## $ Vessel.Volume.V.L. <int> 58479, 58487, …
## $ Vessel.Weight.Wt.Kg. <int> 62574, 62585, …
## $ pH.pH.pH. <dbl> 6.4472, 6.4932…
## $ Temperature.T.K. <dbl> 298.22, 298.17…
## $ Generated.heat.Q.kJ. <dbl> 0.000001, 0.00…
## $ carbon.dioxide.percent.in.off.gas.CO2outgas... <dbl> 0.089514, 0.10…
## $ PAA.flow.Fpaa.PAA.flow..L.h.. <int> 5, 5, 5, 5, 5,…
## $ PAA.concentration.offline.PAA_offline.PAA..g.L...1... <dbl> 0, 0, 0, 0, 14…
## $ Oil.flow.Foil.L.hr. <int> 22, 22, 22, 22…
## $ NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... <dbl> 0.0, 0.0, 0.0,…
## $ Oxygen.Uptake.Rate.OUR..g.min...1... <dbl> 0.48051000, 0.…
## $ Oxygen.in.percent.in.off.gas.O2.O2...... <dbl> 0.19595, 0.203…
## $ Offline.Penicillin.concentration.P_offline.P.g.L...1... <dbl> 0.0000e+00, 0.…
## $ Offline.Biomass.concentratio.X_offline.X.g.L...1... <dbl> 0.00000, 0.000…
## $ Carbon.evolution.rate.CER.g.h. <dbl> 0.034045, 0.03…
## $ Viscosity.Viscosity_offline.centPoise. <dbl> 0.000, 0.000, …
## $ X1..No.Raman.spec <int> 1, 1, 1, 1, 1,…
## $ X1.Raman.spec.recorded <int> 1, 1, 1, 1, 1,…
## $ X2.PAT.control.PAT_ref.PAT.ref. <int> 1, 1, 1, 1, 1,…
## $ Batch.reference.Batch_ref.Batch.ref. <int> 0, 0, 0, 0, 0,…
## $ Batch.ID <int> 0, 0, 0, 0, 0,…
## $ Fault.flag <int> 0, 0, 0, 0, 0,…Penicillin %>% is.na() %>% colSums()## Time..h.
## 0
## Aeration.rate.Fg.L.h.
## 0
## Agitator.RPM.RPM.RPM.
## 0
## Sugar.feed.rate.Fs.L.h.
## 0
## Acid.flow.rate.Fa.L.h.
## 0
## Base.flow.rate.Fb.L.h.
## 0
## Heating.cooling.water.flow.rate.Fc.L.h.
## 0
## Heating.water.flow.rate.Fh.L.h.
## 0
## Water.for.injection.dilution.Fw.L.h.
## 0
## Air.head.pressure.pressure.bar.
## 0
## Dumped.broth.flow.Fremoved.L.h.
## 0
## Substrate.concentration.S.g.L.
## 0
## Dissolved.oxygen.concentration.DO2.mg.L.
## 0
## Penicillin.concentration.P.g.L.
## 0
## Vessel.Volume.V.L.
## 0
## Vessel.Weight.Wt.Kg.
## 0
## pH.pH.pH.
## 0
## Temperature.T.K.
## 0
## Generated.heat.Q.kJ.
## 0
## carbon.dioxide.percent.in.off.gas.CO2outgas...
## 0
## PAA.flow.Fpaa.PAA.flow..L.h..
## 0
## PAA.concentration.offline.PAA_offline.PAA..g.L...1...
## 0
## Oil.flow.Foil.L.hr.
## 0
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1...
## 0
## Oxygen.Uptake.Rate.OUR..g.min...1...
## 0
## Oxygen.in.percent.in.off.gas.O2.O2......
## 0
## Offline.Penicillin.concentration.P_offline.P.g.L...1...
## 0
## Offline.Biomass.concentratio.X_offline.X.g.L...1...
## 0
## Carbon.evolution.rate.CER.g.h.
## 0
## Viscosity.Viscosity_offline.centPoise.
## 0
## X1..No.Raman.spec
## 0
## X1.Raman.spec.recorded
## 0
## X2.PAT.control.PAT_ref.PAT.ref.
## 0
## Batch.reference.Batch_ref.Batch.ref.
## 0
## Batch.ID
## 0
## Fault.flag
## 0summary(Penicillin)## Time..h. Aeration.rate.Fg.L.h. Agitator.RPM.RPM.RPM.
## Min. : 0.20 Min. :30.0 Min. :100
## 1st Qu.: 10.15 1st Qu.:42.0 1st Qu.:100
## Median :115.10 Median :53.5 Median :100
## Mean :115.10 Mean :51.1 Mean :100
## 3rd Qu.:220.05 3rd Qu.:65.0 3rd Qu.:100
## Max. :230.00 Max. :65.0 Max. :100
## Sugar.feed.rate.Fs.L.h. Acid.flow.rate.Fa.L.h. Base.flow.rate.Fb.L.h.
## Min. : 8.00 Min. :0.0000 Min. : 0.000
## 1st Qu.:15.00 1st Qu.:0.0000 1st Qu.: 7.347
## Median :77.50 Median :0.0000 Median :17.698
## Mean :54.48 Mean :0.1973 Mean :22.423
## 3rd Qu.:80.00 3rd Qu.:0.0000 3rd Qu.:35.402
## Max. :80.00 Max. :5.7182 Max. :64.596
## Heating.cooling.water.flow.rate.Fc.L.h. Heating.water.flow.rate.Fh.L.h.
## Min. : 0.0001 Min. : 0.0001
## 1st Qu.: 14.6807 1st Qu.: 0.0001
## Median : 51.4815 Median : 0.1514
## Mean : 67.1249 Mean : 19.3792
## 3rd Qu.:104.6600 3rd Qu.: 10.6500
## Max. :271.7500 Max. :171.3100
## Water.for.injection.dilution.Fw.L.h. Air.head.pressure.pressure.bar.
## Min. : 0 Min. :0.600
## 1st Qu.: 0 1st Qu.:0.600
## Median :125 Median :0.800
## Mean :125 Mean :0.769
## 3rd Qu.:250 3rd Qu.:0.900
## Max. :250 Max. :0.900
## Dumped.broth.flow.Fremoved.L.h. Substrate.concentration.S.g.L.
## Min. :-4000 Min. : 0.00996
## 1st Qu.: 0 1st Qu.: 1.04950
## Median : 0 Median :34.28875
## Mean : -200 Mean :35.35527
## 3rd Qu.: 0 3rd Qu.:69.85250
## Max. : 0 Max. :72.97900
## Dissolved.oxygen.concentration.DO2.mg.L. Penicillin.concentration.P.g.L.
## Min. :11.56 Min. :0.000000
## 1st Qu.:13.03 1st Qu.:0.000972
## Median :13.27 Median :2.813650
## Mean :13.21 Mean :3.014867
## 3rd Qu.:13.39 3rd Qu.:6.019825
## Max. :14.71 Max. :6.454000
## Vessel.Volume.V.L. Vessel.Weight.Wt.Kg. pH.pH.pH. Temperature.T.K.
## Min. :58479 Min. :62574 Min. :6.447 Min. :297.9
## 1st Qu.:58618 1st Qu.:62995 1st Qu.:6.491 1st Qu.:298.0
## Median :63972 Median :71106 Median :6.502 Median :298.1
## Mean :65122 Mean :72234 Mean :6.508 Mean :298.0
## 3rd Qu.:71523 3rd Qu.:81350 3rd Qu.:6.514 3rd Qu.:298.1
## Max. :74552 Max. :84764 Max. :6.647 Max. :298.6
## Generated.heat.Q.kJ. carbon.dioxide.percent.in.off.gas.CO2outgas...
## Min. : 0.00 Min. :0.08951
## 1st Qu.: 12.87 1st Qu.:0.26657
## Median :192.31 Median :0.92810
## Mean :135.55 Mean :0.77052
## 3rd Qu.:240.80 3rd Qu.:1.21920
## Max. :323.36 Max. :1.35120
## PAA.flow.Fpaa.PAA.flow..L.h..
## Min. :0.000
## 1st Qu.:0.000
## Median :4.000
## Mean :2.625
## 3rd Qu.:4.000
## Max. :5.000
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... Oil.flow.Foil.L.hr.
## Min. : 0.0 Min. :22.0
## 1st Qu.: 0.0 1st Qu.:23.0
## Median : 0.0 Median :23.0
## Mean : 139.1 Mean :26.2
## 3rd Qu.: 0.0 3rd Qu.:30.0
## Max. :8254.5 Max. :35.0
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1...
## Min. : 0.00
## 1st Qu.: 0.00
## Median : 0.00
## Mean : 73.55
## 3rd Qu.: 0.00
## Max. :3755.60
## Oxygen.Uptake.Rate.OUR..g.min...1... Oxygen.in.percent.in.off.gas.O2.O2......
## Min. :-0.05674 Min. :0.1889
## 1st Qu.: 0.26927 1st Qu.:0.1963
## Median : 0.32342 Median :0.1999
## Mean : 0.42538 Mean :0.1985
## 3rd Qu.: 0.58850 3rd Qu.:0.2004
## Max. : 1.10910 Max. :0.2060
## Offline.Penicillin.concentration.P_offline.P.g.L...1...
## Min. :0.00000
## 1st Qu.:0.00000
## Median :0.00000
## Mean :0.08812
## 3rd Qu.:0.00000
## Max. :6.23260
## Offline.Biomass.concentratio.X_offline.X.g.L...1...
## Min. : 0.0000
## 1st Qu.: 0.0000
## Median : 0.0000
## Mean : 0.2761
## 3rd Qu.: 0.0000
## Max. :17.9210
## Carbon.evolution.rate.CER.g.h. Viscosity.Viscosity_offline.centPoise.
## Min. :0.03404 Min. : 0.000
## 1st Qu.:0.14162 1st Qu.: 0.000
## Median :0.67132 Median : 0.000
## Mean :0.58549 Mean : 1.838
## 3rd Qu.:1.00778 3rd Qu.: 0.000
## Max. :1.11730 Max. :117.930
## X1..No.Raman.spec X1.Raman.spec.recorded X2.PAT.control.PAT_ref.PAT.ref.
## Min. :1 Min. : 1.0 Min. : 1.0
## 1st Qu.:1 1st Qu.: 1.0 1st Qu.: 1.0
## Median :1 Median : 50.5 Median : 50.5
## Mean :1 Mean : 50.5 Mean : 50.5
## 3rd Qu.:1 3rd Qu.:100.0 3rd Qu.:100.0
## Max. :1 Max. :100.0 Max. :100.0
## Batch.reference.Batch_ref.Batch.ref. Batch.ID Fault.flag
## Min. :0.0 Min. : 0 Min. : 0
## 1st Qu.:0.0 1st Qu.:21511 1st Qu.:21564
## Median :0.5 Median :33056 Median :33321
## Mean :0.5 Mean :32906 Mean :32936
## 3rd Qu.:1.0 3rd Qu.:46270 3rd Qu.:46428
## Max. :1.0 Max. :48990 Max. :49343All variables then already contain positive value, free from NA value and constant/zero variance variable.
names(Penicillin[, sapply(Penicillin, function(v) var(v, na.rm=TRUE)==0)])## [1] "Agitator.RPM.RPM.RPM." "X1..No.Raman.spec"Unfortunately, due to some variables contain NA. Those variables are “Agitator.RPM.RPM.RPM.”, “X1..No.Raman.spec”, which cannot rescale because this column identified as constant/zero column to unit variance, removing those variables are needed.
Penicillin_clean <- Penicillin %>% select(-c(Agitator.RPM.RPM.RPM.,X1..No.Raman.spec))Then, all varaibles shall be converted into same scale to reduce potential to extreme dominance of a variable.
Penicillin_scaled <- scale(Penicillin_clean)
summary(Penicillin_scaled)## Time..h. Aeration.rate.Fg.L.h. Sugar.feed.rate.Fs.L.h.
## Min. :-1.0899 Min. :-1.4507 Min. :-1.5117
## 1st Qu.:-0.9955 1st Qu.:-0.6257 1st Qu.:-1.2840
## Median : 0.0000 Median : 0.1650 Median : 0.7490
## Mean : 0.0000 Mean : 0.0000 Mean : 0.0000
## 3rd Qu.: 0.9955 3rd Qu.: 0.9557 3rd Qu.: 0.8303
## Max. : 1.0899 Max. : 0.9557 Max. : 0.8303
## Acid.flow.rate.Fa.L.h. Base.flow.rate.Fb.L.h.
## Min. :-0.238 Min. :-1.2184
## 1st Qu.:-0.238 1st Qu.:-0.8192
## Median :-0.238 Median :-0.2567
## Mean : 0.000 Mean : 0.0000
## 3rd Qu.:-0.238 3rd Qu.: 0.7052
## Max. : 6.659 Max. : 2.2915
## Heating.cooling.water.flow.rate.Fc.L.h. Heating.water.flow.rate.Fh.L.h.
## Min. :-1.1582 Min. :-0.5359
## 1st Qu.:-0.9049 1st Qu.:-0.5359
## Median :-0.2699 Median :-0.5317
## Mean : 0.0000 Mean : 0.0000
## 3rd Qu.: 0.6477 3rd Qu.:-0.2414
## Max. : 3.5308 Max. : 4.2015
## Water.for.injection.dilution.Fw.L.h. Air.head.pressure.pressure.bar.
## Min. :-0.9975 Min. :-1.2448
## 1st Qu.:-0.9975 1st Qu.:-1.2448
## Median : 0.0000 Median : 0.2283
## Mean : 0.0000 Mean : 0.0000
## 3rd Qu.: 0.9975 3rd Qu.: 0.9649
## Max. : 0.9975 Max. : 0.9649
## Dumped.broth.flow.Fremoved.L.h. Substrate.concentration.S.g.L.
## Min. :-4.3480 Min. :-1.02166
## 1st Qu.: 0.2288 1st Qu.:-0.99162
## Median : 0.2288 Median :-0.03083
## Mean : 0.0000 Mean : 0.00000
## 3rd Qu.: 0.2288 3rd Qu.: 0.99715
## Max. : 0.2288 Max. : 1.08752
## Dissolved.oxygen.concentration.DO2.mg.L. Penicillin.concentration.P.g.L.
## Min. :-2.39842 Min. :-0.99621
## 1st Qu.:-0.26360 1st Qu.:-0.99588
## Median : 0.08516 Median :-0.06649
## Mean : 0.00000 Mean : 0.00000
## 3rd Qu.: 0.26100 3rd Qu.: 0.99293
## Max. : 2.18867 Max. : 1.13640
## Vessel.Volume.V.L. Vessel.Weight.Wt.Kg. pH.pH.pH. Temperature.T.K.
## Min. :-1.0144 Min. :-1.0424 Min. :-2.0716 Min. :-1.8211
## 1st Qu.:-0.9932 1st Qu.:-0.9970 1st Qu.:-0.5800 1st Qu.:-0.7394
## Median :-0.1757 Median :-0.1217 Median :-0.1986 Median : 0.1455
## Mean : 0.0000 Mean : 0.0000 Mean : 0.0000 Mean : 0.0000
## 3rd Qu.: 0.9773 3rd Qu.: 0.9837 3rd Qu.: 0.1912 3rd Qu.: 0.5388
## Max. : 1.4399 Max. : 1.3522 Max. : 4.6950 Max. : 5.2587
## Generated.heat.Q.kJ. carbon.dioxide.percent.in.off.gas.CO2outgas...
## Min. :-1.1748 Min. :-1.4477
## 1st Qu.:-1.0633 1st Qu.:-1.0713
## Median : 0.4920 Median : 0.3350
## Mean : 0.0000 Mean : 0.0000
## 3rd Qu.: 0.9123 3rd Qu.: 0.9539
## Max. : 1.6278 Max. : 1.2345
## PAA.flow.Fpaa.PAA.flow..L.h..
## Min. :-1.2725
## 1st Qu.:-1.2725
## Median : 0.6665
## Mean : 0.0000
## 3rd Qu.: 0.6665
## Max. : 1.1513
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... Oil.flow.Foil.L.hr.
## Min. :-0.137 Min. :-0.9621
## 1st Qu.:-0.137 1st Qu.:-0.7331
## Median :-0.137 Median :-0.7331
## Mean : 0.000 Mean : 0.0000
## 3rd Qu.:-0.137 3rd Qu.: 0.8705
## Max. : 7.993 Max. : 2.0159
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1...
## Min. :-0.1512
## 1st Qu.:-0.1512
## Median :-0.1512
## Mean : 0.0000
## 3rd Qu.:-0.1512
## Max. : 7.5680
## Oxygen.Uptake.Rate.OUR..g.min...1... Oxygen.in.percent.in.off.gas.O2.O2......
## Min. :-1.7145 Min. :-2.4729
## 1st Qu.:-0.5552 1st Qu.:-0.5541
## Median :-0.3626 Median : 0.3679
## Mean : 0.0000 Mean : 0.0000
## 3rd Qu.: 0.5801 3rd Qu.: 0.4846
## Max. : 2.4315 Max. : 1.9450
## Offline.Penicillin.concentration.P_offline.P.g.L...1...
## Min. :-0.123
## 1st Qu.:-0.123
## Median :-0.123
## Mean : 0.000
## 3rd Qu.:-0.123
## Max. : 8.575
## Offline.Biomass.concentratio.X_offline.X.g.L...1...
## Min. :-0.1307
## 1st Qu.:-0.1307
## Median :-0.1307
## Mean : 0.0000
## 3rd Qu.:-0.1307
## Max. : 8.3522
## Carbon.evolution.rate.CER.g.h. Viscosity.Viscosity_offline.centPoise.
## Min. :-1.2710 Min. :-0.1282
## 1st Qu.:-1.0230 1st Qu.:-0.1282
## Median : 0.1978 Median :-0.1282
## Mean : 0.0000 Mean : 0.0000
## 3rd Qu.: 0.9733 3rd Qu.:-0.1282
## Max. : 1.2257 Max. : 8.0961
## X1.Raman.spec.recorded X2.PAT.control.PAT_ref.PAT.ref.
## Min. :-0.9975 Min. :-0.9975
## 1st Qu.:-0.9975 1st Qu.:-0.9975
## Median : 0.0000 Median : 0.0000
## Mean : 0.0000 Mean : 0.0000
## 3rd Qu.: 0.9975 3rd Qu.: 0.9975
## Max. : 0.9975 Max. : 0.9975
## Batch.reference.Batch_ref.Batch.ref. Batch.ID Fault.flag
## Min. :-0.9975 Min. :-2.29996 Min. :-2.29886
## 1st Qu.:-0.9975 1st Qu.:-0.79650 1st Qu.:-0.79376
## Median : 0.0000 Median : 0.01046 Median : 0.02686
## Mean : 0.0000 Mean : 0.00000 Mean : 0.00000
## 3rd Qu.: 0.9975 3rd Qu.: 0.93400 3rd Qu.: 0.94177
## Max. : 0.9975 Max. : 1.12415 Max. : 1.145214 Scaling Variables
plot(prcomp(Penicillin_scaled))
Transform date set to pca used prcomp funtion and below the sd, rotation and projection of each PC.
prcomp(Penicillin_scaled)## Standard deviations (1, .., p=34):
## [1] 4.358686e+00 2.205296e+00 2.100134e+00 1.418142e+00 1.166698e+00
## [6] 8.085847e-01 6.500733e-01 5.784470e-01 5.028894e-01 4.349995e-01
## [11] 3.567104e-01 3.350405e-01 2.712734e-01 2.447796e-01 2.091135e-01
## [16] 1.934269e-01 1.381817e-01 1.366587e-01 6.953700e-02 4.144815e-02
## [21] 3.368249e-02 3.240153e-02 2.995979e-02 2.311646e-02 1.546378e-02
## [26] 1.363907e-02 3.017046e-03 1.505562e-03 7.818226e-04 5.366227e-05
## [31] 1.367838e-05 4.210701e-16 4.210701e-16 4.210701e-16
##
## Rotation (n x k) = (34 x 34):
## PC1
## Time..h. 0.22770584
## Aeration.rate.Fg.L.h. 0.21625494
## Sugar.feed.rate.Fs.L.h. 0.18791620
## Acid.flow.rate.Fa.L.h. 0.04524415
## Base.flow.rate.Fb.L.h. -0.16832698
## Heating.cooling.water.flow.rate.Fc.L.h. -0.13267186
## Heating.water.flow.rate.Fh.L.h. 0.10860797
## Water.for.injection.dilution.Fw.L.h. 0.22839846
## Air.head.pressure.pressure.bar. 0.22084594
## Dumped.broth.flow.Fremoved.L.h. -0.05818216
## Substrate.concentration.S.g.L. 0.22820718
## Dissolved.oxygen.concentration.DO2.mg.L. 0.01699940
## Penicillin.concentration.P.g.L. 0.22811631
## Vessel.Volume.V.L. 0.22492886
## Vessel.Weight.Wt.Kg. 0.22609929
## pH.pH.pH. 0.04783488
## Temperature.T.K. -0.12103745
## Generated.heat.Q.kJ. 0.22089665
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.21999985
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.16183831
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.03279132
## Oil.flow.Foil.L.hr. -0.17494631
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.02621682
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.10089045
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.10026949
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.03656895
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.03441640
## Carbon.evolution.rate.CER.g.h. 0.22463193
## Viscosity.Viscosity_offline.centPoise. 0.03531000
## X1.Raman.spec.recorded 0.22839846
## X2.PAT.control.PAT_ref.PAT.ref. 0.22839846
## Batch.reference.Batch_ref.Batch.ref. 0.22839846
## Batch.ID 0.21474923
## Fault.flag 0.21466435
## PC2
## Time..h. -0.013569704
## Aeration.rate.Fg.L.h. -0.017540578
## Sugar.feed.rate.Fs.L.h. -0.021410561
## Acid.flow.rate.Fa.L.h. -0.043978179
## Base.flow.rate.Fb.L.h. 0.006316711
## Heating.cooling.water.flow.rate.Fc.L.h. 0.003390360
## Heating.water.flow.rate.Fh.L.h. 0.009200547
## Water.for.injection.dilution.Fw.L.h. -0.016036621
## Air.head.pressure.pressure.bar. -0.019063856
## Dumped.broth.flow.Fremoved.L.h. 0.049567917
## Substrate.concentration.S.g.L. -0.013083921
## Dissolved.oxygen.concentration.DO2.mg.L. 0.015731993
## Penicillin.concentration.P.g.L. -0.020242944
## Vessel.Volume.V.L. -0.005733205
## Vessel.Weight.Wt.Kg. -0.008072996
## pH.pH.pH. -0.058057137
## Temperature.T.K. 0.014709574
## Generated.heat.Q.kJ. -0.015241275
## carbon.dioxide.percent.in.off.gas.CO2outgas... -0.020927617
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.004138840
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.447758597
## Oil.flow.Foil.L.hr. 0.002757476
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.437072868
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.006296079
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.005729786
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.443015637
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.446674806
## Carbon.evolution.rate.CER.g.h. -0.019762235
## Viscosity.Viscosity_offline.centPoise. 0.445935164
## X1.Raman.spec.recorded -0.016036621
## X2.PAT.control.PAT_ref.PAT.ref. -0.016036621
## Batch.reference.Batch_ref.Batch.ref. -0.016036621
## Batch.ID -0.025455344
## Fault.flag -0.025518573
## PC3
## Time..h. 0.041384471
## Aeration.rate.Fg.L.h. 0.136324640
## Sugar.feed.rate.Fs.L.h. 0.223741196
## Acid.flow.rate.Fa.L.h. -0.040044762
## Base.flow.rate.Fb.L.h. 0.213223346
## Heating.cooling.water.flow.rate.Fc.L.h. 0.318861006
## Heating.water.flow.rate.Fh.L.h. 0.003051813
## Water.for.injection.dilution.Fw.L.h. 0.024745266
## Air.head.pressure.pressure.bar. 0.099547498
## Dumped.broth.flow.Fremoved.L.h. -0.026474207
## Substrate.concentration.S.g.L. 0.019268374
## Dissolved.oxygen.concentration.DO2.mg.L. -0.457431998
## Penicillin.concentration.P.g.L. 0.025483280
## Vessel.Volume.V.L. 0.033832170
## Vessel.Weight.Wt.Kg. 0.037844554
## pH.pH.pH. -0.048330696
## Temperature.T.K. -0.014311294
## Generated.heat.Q.kJ. 0.065956997
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.127908123
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.272002435
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.010727245
## Oil.flow.Foil.L.hr. 0.273698652
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.004999218
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.418614101
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.419555604
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.014679296
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.017593882
## Carbon.evolution.rate.CER.g.h. 0.091467641
## Viscosity.Viscosity_offline.centPoise. 0.015415293
## X1.Raman.spec.recorded 0.024745266
## X2.PAT.control.PAT_ref.PAT.ref. 0.024745266
## Batch.reference.Batch_ref.Batch.ref. 0.024745266
## Batch.ID 0.105283003
## Fault.flag 0.105952543
## PC4
## Time..h. 0.0376662634
## Aeration.rate.Fg.L.h. 0.0195751907
## Sugar.feed.rate.Fs.L.h. 0.0154334884
## Acid.flow.rate.Fa.L.h. -0.5343101828
## Base.flow.rate.Fb.L.h. 0.0671366580
## Heating.cooling.water.flow.rate.Fc.L.h. -0.0181085452
## Heating.water.flow.rate.Fh.L.h. -0.0970143633
## Water.for.injection.dilution.Fw.L.h. 0.0228744673
## Air.head.pressure.pressure.bar. 0.0194621614
## Dumped.broth.flow.Fremoved.L.h. 0.5188019939
## Substrate.concentration.S.g.L. 0.0375775332
## Dissolved.oxygen.concentration.DO2.mg.L. 0.0598165813
## Penicillin.concentration.P.g.L. 0.0008449866
## Vessel.Volume.V.L. 0.0531046332
## Vessel.Weight.Wt.Kg. 0.0468210063
## pH.pH.pH. -0.6234959038
## Temperature.T.K. -0.1263224650
## Generated.heat.Q.kJ. -0.0096524075
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.0046185345
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.0036456960
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.0379010332
## Oil.flow.Foil.L.hr. -0.0089061164
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.0482690105
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.0550879319
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.0318492482
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.0290159828
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.0315018085
## Carbon.evolution.rate.CER.g.h. 0.0065998913
## Viscosity.Viscosity_offline.centPoise. -0.0314555190
## X1.Raman.spec.recorded 0.0228744673
## X2.PAT.control.PAT_ref.PAT.ref. 0.0228744673
## Batch.reference.Batch_ref.Batch.ref. 0.0228744673
## Batch.ID 0.0222688640
## Fault.flag 0.0224685888
## PC5
## Time..h. -0.006533934
## Aeration.rate.Fg.L.h. 0.007501678
## Sugar.feed.rate.Fs.L.h. -0.014524099
## Acid.flow.rate.Fa.L.h. -0.184566780
## Base.flow.rate.Fb.L.h. 0.014129155
## Heating.cooling.water.flow.rate.Fc.L.h. -0.095407998
## Heating.water.flow.rate.Fh.L.h. 0.699218207
## Water.for.injection.dilution.Fw.L.h. -0.008585032
## Air.head.pressure.pressure.bar. 0.005740708
## Dumped.broth.flow.Fremoved.L.h. 0.005576110
## Substrate.concentration.S.g.L. -0.007676034
## Dissolved.oxygen.concentration.DO2.mg.L. 0.025758154
## Penicillin.concentration.P.g.L. -0.010752247
## Vessel.Volume.V.L. 0.002847072
## Vessel.Weight.Wt.Kg. 0.000569354
## pH.pH.pH. -0.074736660
## Temperature.T.K. 0.653248431
## Generated.heat.Q.kJ. 0.171725273
## carbon.dioxide.percent.in.off.gas.CO2outgas... -0.008406209
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.051243973
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.013371214
## Oil.flow.Foil.L.hr. 0.021286928
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.020697243
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.011592422
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.013050378
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.007890513
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.011115631
## Carbon.evolution.rate.CER.g.h. -0.007356829
## Viscosity.Viscosity_offline.centPoise. -0.009788268
## X1.Raman.spec.recorded -0.008585032
## X2.PAT.control.PAT_ref.PAT.ref. -0.008585032
## Batch.reference.Batch_ref.Batch.ref. -0.008585032
## Batch.ID -0.002087435
## Fault.flag -0.001048552
## PC6
## Time..h. 0.012458598
## Aeration.rate.Fg.L.h. 0.019927517
## Sugar.feed.rate.Fs.L.h. 0.084001301
## Acid.flow.rate.Fa.L.h. 0.634501845
## Base.flow.rate.Fb.L.h. 0.064712581
## Heating.cooling.water.flow.rate.Fc.L.h. -0.153236637
## Heating.water.flow.rate.Fh.L.h. 0.173034518
## Water.for.injection.dilution.Fw.L.h. 0.004005011
## Air.head.pressure.pressure.bar. 0.032693183
## Dumped.broth.flow.Fremoved.L.h. 0.715680253
## Substrate.concentration.S.g.L. 0.006870687
## Dissolved.oxygen.concentration.DO2.mg.L. -0.055869896
## Penicillin.concentration.P.g.L. -0.003182546
## Vessel.Volume.V.L. -0.068273056
## Vessel.Weight.Wt.Kg. -0.052058357
## pH.pH.pH. 0.026955826
## Temperature.T.K. -0.034326417
## Generated.heat.Q.kJ. 0.009117316
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.006030151
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.007906023
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.001674480
## Oil.flow.Foil.L.hr. 0.046047373
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.003203402
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.024550490
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.033104113
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.004287098
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.003917991
## Carbon.evolution.rate.CER.g.h. -0.002009488
## Viscosity.Viscosity_offline.centPoise. -0.004535153
## X1.Raman.spec.recorded 0.004005011
## X2.PAT.control.PAT_ref.PAT.ref. 0.004005011
## Batch.reference.Batch_ref.Batch.ref. 0.004005011
## Batch.ID -0.033304345
## Fault.flag -0.034942561
## PC7
## Time..h. -0.014718396
## Aeration.rate.Fg.L.h. -0.055232713
## Sugar.feed.rate.Fs.L.h. 0.214304503
## Acid.flow.rate.Fa.L.h. -0.238481494
## Base.flow.rate.Fb.L.h. 0.533011470
## Heating.cooling.water.flow.rate.Fc.L.h. -0.465634085
## Heating.water.flow.rate.Fh.L.h. 0.209563544
## Water.for.injection.dilution.Fw.L.h. -0.021613684
## Air.head.pressure.pressure.bar. 0.017661664
## Dumped.broth.flow.Fremoved.L.h. -0.053836315
## Substrate.concentration.S.g.L. -0.022671093
## Dissolved.oxygen.concentration.DO2.mg.L. -0.096595287
## Penicillin.concentration.P.g.L. -0.027833286
## Vessel.Volume.V.L. 0.029830922
## Vessel.Weight.Wt.Kg. 0.020709369
## pH.pH.pH. 0.226972701
## Temperature.T.K. -0.289273760
## Generated.heat.Q.kJ. -0.092361113
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.037573124
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.332611670
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.007227411
## Oil.flow.Foil.L.hr. -0.023273001
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.054257925
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.102995435
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.082540951
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.024543966
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.011734992
## Carbon.evolution.rate.CER.g.h. 0.015078019
## Viscosity.Viscosity_offline.centPoise. -0.017300672
## X1.Raman.spec.recorded -0.021613684
## X2.PAT.control.PAT_ref.PAT.ref. -0.021613684
## Batch.reference.Batch_ref.Batch.ref. -0.021613684
## Batch.ID -0.164640331
## Fault.flag -0.164261585
## PC8
## Time..h. 0.061508759
## Aeration.rate.Fg.L.h. 0.133183113
## Sugar.feed.rate.Fs.L.h. -0.075722633
## Acid.flow.rate.Fa.L.h. -0.145875251
## Base.flow.rate.Fb.L.h. 0.398866829
## Heating.cooling.water.flow.rate.Fc.L.h. 0.468240103
## Heating.water.flow.rate.Fh.L.h. -0.244972633
## Water.for.injection.dilution.Fw.L.h. 0.057315094
## Air.head.pressure.pressure.bar. 0.023639184
## Dumped.broth.flow.Fremoved.L.h. 0.277077211
## Substrate.concentration.S.g.L. 0.061681911
## Dissolved.oxygen.concentration.DO2.mg.L. 0.036602678
## Penicillin.concentration.P.g.L. 0.044137078
## Vessel.Volume.V.L. 0.043139423
## Vessel.Weight.Wt.Kg. 0.044568673
## pH.pH.pH. 0.392818670
## Temperature.T.K. 0.319496158
## Generated.heat.Q.kJ. 0.110066552
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.003898025
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.152006994
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.012212893
## Oil.flow.Foil.L.hr. -0.235745559
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.087066818
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.068881185
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.140986160
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.048459624
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.023849756
## Carbon.evolution.rate.CER.g.h. 0.030886802
## Viscosity.Viscosity_offline.centPoise. -0.025725212
## X1.Raman.spec.recorded 0.057315094
## X2.PAT.control.PAT_ref.PAT.ref. 0.057315094
## Batch.reference.Batch_ref.Batch.ref. 0.057315094
## Batch.ID -0.118874559
## Fault.flag -0.116137514
## PC9
## Time..h. -0.022454892
## Aeration.rate.Fg.L.h. -0.049684263
## Sugar.feed.rate.Fs.L.h. 0.397333505
## Acid.flow.rate.Fa.L.h. 0.109975818
## Base.flow.rate.Fb.L.h. -0.318436441
## Heating.cooling.water.flow.rate.Fc.L.h. 0.079393983
## Heating.water.flow.rate.Fh.L.h. -0.195968338
## Water.for.injection.dilution.Fw.L.h. -0.027634043
## Air.head.pressure.pressure.bar. 0.100806285
## Dumped.broth.flow.Fremoved.L.h. -0.067035589
## Substrate.concentration.S.g.L. -0.035382828
## Dissolved.oxygen.concentration.DO2.mg.L. -0.054456829
## Penicillin.concentration.P.g.L. -0.029040294
## Vessel.Volume.V.L. 0.001764422
## Vessel.Weight.Wt.Kg. -0.002049049
## pH.pH.pH. -0.249627906
## Temperature.T.K. 0.258779463
## Generated.heat.Q.kJ. 0.068089750
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.051650360
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.540012788
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.001596532
## Oil.flow.Foil.L.hr. -0.065868571
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.019373827
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.188681803
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.141791423
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.008076985
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.006582625
## Carbon.evolution.rate.CER.g.h. 0.024656572
## Viscosity.Viscosity_offline.centPoise. 0.003235619
## X1.Raman.spec.recorded -0.027634043
## X2.PAT.control.PAT_ref.PAT.ref. -0.027634043
## Batch.reference.Batch_ref.Batch.ref. -0.027634043
## Batch.ID -0.290003811
## Fault.flag -0.291069478
## PC10
## Time..h. 0.007368023
## Aeration.rate.Fg.L.h. 0.078837523
## Sugar.feed.rate.Fs.L.h. -0.353049804
## Acid.flow.rate.Fa.L.h. 0.320297359
## Base.flow.rate.Fb.L.h. 0.352521800
## Heating.cooling.water.flow.rate.Fc.L.h. 0.074682240
## Heating.water.flow.rate.Fh.L.h. 0.078646598
## Water.for.injection.dilution.Fw.L.h. 0.035819733
## Air.head.pressure.pressure.bar. -0.187557538
## Dumped.broth.flow.Fremoved.L.h. -0.236798010
## Substrate.concentration.S.g.L. 0.025889658
## Dissolved.oxygen.concentration.DO2.mg.L. -0.224826585
## Penicillin.concentration.P.g.L. 0.055556607
## Vessel.Volume.V.L. -0.005739401
## Vessel.Weight.Wt.Kg. -0.002262903
## pH.pH.pH. -0.471055664
## Temperature.T.K. 0.009889009
## Generated.heat.Q.kJ. -0.069392040
## carbon.dioxide.percent.in.off.gas.CO2outgas... -0.072981112
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.221537935
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.009895614
## Oil.flow.Foil.L.hr. -0.422204062
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.015372219
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.076919578
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.013336505
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.022221679
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.017415320
## Carbon.evolution.rate.CER.g.h. -0.015750406
## Viscosity.Viscosity_offline.centPoise. -0.008272521
## X1.Raman.spec.recorded 0.035819733
## X2.PAT.control.PAT_ref.PAT.ref. 0.035819733
## Batch.reference.Batch_ref.Batch.ref. 0.035819733
## Batch.ID 0.079845706
## Fault.flag 0.079690239
## PC11
## Time..h. -0.06152017
## Aeration.rate.Fg.L.h. -0.17921669
## Sugar.feed.rate.Fs.L.h. 0.16144713
## Acid.flow.rate.Fa.L.h. -0.02587831
## Base.flow.rate.Fb.L.h. 0.13394244
## Heating.cooling.water.flow.rate.Fc.L.h. -0.04723808
## Heating.water.flow.rate.Fh.L.h. -0.17789397
## Water.for.injection.dilution.Fw.L.h. -0.02711510
## Air.head.pressure.pressure.bar. -0.09452868
## Dumped.broth.flow.Fremoved.L.h. 0.04543940
## Substrate.concentration.S.g.L. -0.04462277
## Dissolved.oxygen.concentration.DO2.mg.L. -0.11007323
## Penicillin.concentration.P.g.L. 0.01558042
## Vessel.Volume.V.L. -0.20876611
## Vessel.Weight.Wt.Kg. -0.17298829
## pH.pH.pH. 0.05484241
## Temperature.T.K. 0.20960731
## Generated.heat.Q.kJ. 0.02018092
## carbon.dioxide.percent.in.off.gas.CO2outgas... -0.05276491
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.41170499
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.01491438
## Oil.flow.Foil.L.hr. 0.25479056
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.16645118
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.13860344
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.07076252
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.10187712
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.04831666
## Carbon.evolution.rate.CER.g.h. -0.05520468
## Viscosity.Viscosity_offline.centPoise. 0.05962940
## X1.Raman.spec.recorded -0.02711510
## X2.PAT.control.PAT_ref.PAT.ref. -0.02711510
## Batch.reference.Batch_ref.Batch.ref. -0.02711510
## Batch.ID 0.46076210
## Fault.flag 0.46413929
## PC12
## Time..h. 0.032018798
## Aeration.rate.Fg.L.h. -0.013148983
## Sugar.feed.rate.Fs.L.h. 0.166350279
## Acid.flow.rate.Fa.L.h. 0.232543850
## Base.flow.rate.Fb.L.h. 0.452277308
## Heating.cooling.water.flow.rate.Fc.L.h. -0.101367422
## Heating.water.flow.rate.Fh.L.h. -0.210731588
## Water.for.injection.dilution.Fw.L.h. 0.014040660
## Air.head.pressure.pressure.bar. 0.196495750
## Dumped.broth.flow.Fremoved.L.h. -0.194465805
## Substrate.concentration.S.g.L. 0.022897068
## Dissolved.oxygen.concentration.DO2.mg.L. 0.489256495
## Penicillin.concentration.P.g.L. -0.004241974
## Vessel.Volume.V.L. 0.093123122
## Vessel.Weight.Wt.Kg. 0.078639443
## pH.pH.pH. -0.231034684
## Temperature.T.K. 0.173769229
## Generated.heat.Q.kJ. 0.093457013
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.058837974
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.226218393
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.025689800
## Oil.flow.Foil.L.hr. 0.179708088
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.297025326
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.070250781
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.011594407
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.167332556
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.057586083
## Carbon.evolution.rate.CER.g.h. 0.036624931
## Viscosity.Viscosity_offline.centPoise. 0.100657196
## X1.Raman.spec.recorded 0.014040660
## X2.PAT.control.PAT_ref.PAT.ref. 0.014040660
## Batch.reference.Batch_ref.Batch.ref. 0.014040660
## Batch.ID -0.069922426
## Fault.flag -0.070409970
## PC13
## Time..h. -0.094320360
## Aeration.rate.Fg.L.h. 0.153493269
## Sugar.feed.rate.Fs.L.h. 0.058303833
## Acid.flow.rate.Fa.L.h. -0.044994814
## Base.flow.rate.Fb.L.h. -0.028205404
## Heating.cooling.water.flow.rate.Fc.L.h. 0.402237690
## Heating.water.flow.rate.Fh.L.h. 0.357423112
## Water.for.injection.dilution.Fw.L.h. -0.106466855
## Air.head.pressure.pressure.bar. 0.249617808
## Dumped.broth.flow.Fremoved.L.h. 0.019872408
## Substrate.concentration.S.g.L. -0.144549835
## Dissolved.oxygen.concentration.DO2.mg.L. 0.215523392
## Penicillin.concentration.P.g.L. -0.083719700
## Vessel.Volume.V.L. -0.172097383
## Vessel.Weight.Wt.Kg. -0.149748475
## pH.pH.pH. 0.048129297
## Temperature.T.K. -0.340572293
## Generated.heat.Q.kJ. 0.008313938
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.080257096
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.141562848
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.043271925
## Oil.flow.Foil.L.hr. -0.224641530
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.391039065
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.089686563
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.053589581
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.220961773
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.082217074
## Carbon.evolution.rate.CER.g.h. 0.027406660
## Viscosity.Viscosity_offline.centPoise. 0.120886657
## X1.Raman.spec.recorded -0.106466855
## X2.PAT.control.PAT_ref.PAT.ref. -0.106466855
## Batch.reference.Batch_ref.Batch.ref. -0.106466855
## Batch.ID 0.053829736
## Fault.flag 0.049709984
## PC14
## Time..h. -0.066331211
## Aeration.rate.Fg.L.h. 0.001282018
## Sugar.feed.rate.Fs.L.h. 0.136929824
## Acid.flow.rate.Fa.L.h. 0.084626677
## Base.flow.rate.Fb.L.h. 0.115263954
## Heating.cooling.water.flow.rate.Fc.L.h. 0.152867246
## Heating.water.flow.rate.Fh.L.h. 0.081296062
## Water.for.injection.dilution.Fw.L.h. -0.065939900
## Air.head.pressure.pressure.bar. 0.258950282
## Dumped.broth.flow.Fremoved.L.h. -0.089066067
## Substrate.concentration.S.g.L. -0.101656089
## Dissolved.oxygen.concentration.DO2.mg.L. 0.339636486
## Penicillin.concentration.P.g.L. -0.037987199
## Vessel.Volume.V.L. -0.145619131
## Vessel.Weight.Wt.Kg. -0.123332109
## pH.pH.pH. -0.142204727
## Temperature.T.K. -0.080386850
## Generated.heat.Q.kJ. 0.077260832
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.082017005
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.055716273
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.064464415
## Oil.flow.Foil.L.hr. 0.061523551
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.630649655
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.001820586
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.007899085
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.349969319
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.125173039
## Carbon.evolution.rate.CER.g.h. 0.028734431
## Viscosity.Viscosity_offline.centPoise. -0.202042297
## X1.Raman.spec.recorded -0.065939900
## X2.PAT.control.PAT_ref.PAT.ref. -0.065939900
## Batch.reference.Batch_ref.Batch.ref. -0.065939900
## Batch.ID 0.146012301
## Fault.flag 0.145515154
## PC15
## Time..h. 0.063365079
## Aeration.rate.Fg.L.h. -0.137547519
## Sugar.feed.rate.Fs.L.h. -0.189339469
## Acid.flow.rate.Fa.L.h. 0.071926728
## Base.flow.rate.Fb.L.h. -0.018916448
## Heating.cooling.water.flow.rate.Fc.L.h. 0.238351618
## Heating.water.flow.rate.Fh.L.h. 0.162766215
## Water.for.injection.dilution.Fw.L.h. -0.036180928
## Air.head.pressure.pressure.bar. -0.146866992
## Dumped.broth.flow.Fremoved.L.h. 0.053153648
## Substrate.concentration.S.g.L. 0.070782629
## Dissolved.oxygen.concentration.DO2.mg.L. 0.244682949
## Penicillin.concentration.P.g.L. -0.189671835
## Vessel.Volume.V.L. 0.517303247
## Vessel.Weight.Wt.Kg. 0.399551199
## pH.pH.pH. 0.041207076
## Temperature.T.K. -0.101026775
## Generated.heat.Q.kJ. -0.090488498
## carbon.dioxide.percent.in.off.gas.CO2outgas... -0.124995338
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.314243154
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.002976423
## Oil.flow.Foil.L.hr. 0.319453839
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.001789519
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.107014303
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.146381374
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.036405703
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.004467669
## Carbon.evolution.rate.CER.g.h. -0.110165036
## Viscosity.Viscosity_offline.centPoise. 0.014714814
## X1.Raman.spec.recorded -0.036180928
## X2.PAT.control.PAT_ref.PAT.ref. -0.036180928
## Batch.reference.Batch_ref.Batch.ref. -0.036180928
## Batch.ID 0.073426950
## Fault.flag 0.078438490
## PC16
## Time..h. 0.0184051792
## Aeration.rate.Fg.L.h. 0.1146565675
## Sugar.feed.rate.Fs.L.h. 0.0978933880
## Acid.flow.rate.Fa.L.h. 0.0806119141
## Base.flow.rate.Fb.L.h. 0.0865316507
## Heating.cooling.water.flow.rate.Fc.L.h. 0.2572843203
## Heating.water.flow.rate.Fh.L.h. 0.1950785042
## Water.for.injection.dilution.Fw.L.h. 0.0401843666
## Air.head.pressure.pressure.bar. -0.0811645556
## Dumped.broth.flow.Fremoved.L.h. -0.1280154456
## Substrate.concentration.S.g.L. 0.0323404135
## Dissolved.oxygen.concentration.DO2.mg.L. -0.2829501577
## Penicillin.concentration.P.g.L. 0.0645180010
## Vessel.Volume.V.L. -0.0361698448
## Vessel.Weight.Wt.Kg. -0.0213198098
## pH.pH.pH. -0.1585321547
## Temperature.T.K. -0.1511903401
## Generated.heat.Q.kJ. 0.0220838850
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.0050521496
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.0753118399
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.0007399452
## Oil.flow.Foil.L.hr. 0.4910684103
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.0141044198
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.3388721722
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.4969766721
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.0014268662
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.0127687718
## Carbon.evolution.rate.CER.g.h. 0.0315662125
## Viscosity.Viscosity_offline.centPoise. -0.0132505434
## X1.Raman.spec.recorded 0.0401843666
## X2.PAT.control.PAT_ref.PAT.ref. 0.0401843666
## Batch.reference.Batch_ref.Batch.ref. 0.0401843666
## Batch.ID -0.2111153193
## Fault.flag -0.1974276544
## PC17
## Time..h. -0.0009414251
## Aeration.rate.Fg.L.h. 0.5798467052
## Sugar.feed.rate.Fs.L.h. -0.4800408919
## Acid.flow.rate.Fa.L.h. -0.0462901930
## Base.flow.rate.Fb.L.h. -0.0592740971
## Heating.cooling.water.flow.rate.Fc.L.h. -0.2092463886
## Heating.water.flow.rate.Fh.L.h. -0.1127037877
## Water.for.injection.dilution.Fw.L.h. 0.0248346686
## Air.head.pressure.pressure.bar. 0.1571253689
## Dumped.broth.flow.Fremoved.L.h. 0.0133341035
## Substrate.concentration.S.g.L. -0.0230510442
## Dissolved.oxygen.concentration.DO2.mg.L. 0.1274992656
## Penicillin.concentration.P.g.L. 0.0798749534
## Vessel.Volume.V.L. -0.1671522727
## Vessel.Weight.Wt.Kg. -0.1246311565
## pH.pH.pH. 0.0265994584
## Temperature.T.K. 0.0624276978
## Generated.heat.Q.kJ. 0.0004925214
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.0012538999
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.2412093261
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.0087788538
## Oil.flow.Foil.L.hr. 0.3698733541
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.0119654475
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.2592379660
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.0381224364
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.0159359791
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.0160878906
## Carbon.evolution.rate.CER.g.h. 0.0675714241
## Viscosity.Viscosity_offline.centPoise. -0.0049331471
## X1.Raman.spec.recorded 0.0248346686
## X2.PAT.control.PAT_ref.PAT.ref. 0.0248346686
## Batch.reference.Batch_ref.Batch.ref. 0.0248346686
## Batch.ID -0.0422045393
## Fault.flag -0.0431843816
## PC18
## Time..h. -0.0769262121
## Aeration.rate.Fg.L.h. 0.4424318850
## Sugar.feed.rate.Fs.L.h. 0.2306228054
## Acid.flow.rate.Fa.L.h. 0.0333831982
## Base.flow.rate.Fb.L.h. 0.0001203153
## Heating.cooling.water.flow.rate.Fc.L.h. -0.1637239939
## Heating.water.flow.rate.Fh.L.h. -0.1186965925
## Water.for.injection.dilution.Fw.L.h. -0.1891721574
## Air.head.pressure.pressure.bar. 0.0375830649
## Dumped.broth.flow.Fremoved.L.h. -0.0030281198
## Substrate.concentration.S.g.L. -0.1235240546
## Dissolved.oxygen.concentration.DO2.mg.L. -0.1633385131
## Penicillin.concentration.P.g.L. -0.3076843654
## Vessel.Volume.V.L. 0.2842796189
## Vessel.Weight.Wt.Kg. 0.1950569331
## pH.pH.pH. -0.0096197758
## Temperature.T.K. 0.1062893814
## Generated.heat.Q.kJ. -0.0252343567
## carbon.dioxide.percent.in.off.gas.CO2outgas... -0.1046938392
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.1084310417
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.0170732109
## Oil.flow.Foil.L.hr. -0.1386169936
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.0255123424
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.1561640049
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.4293636849
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.0220125748
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.0273899491
## Carbon.evolution.rate.CER.g.h. -0.0855927077
## Viscosity.Viscosity_offline.centPoise. 0.0067024606
## X1.Raman.spec.recorded -0.1891721574
## X2.PAT.control.PAT_ref.PAT.ref. -0.1891721574
## Batch.reference.Batch_ref.Batch.ref. -0.1891721574
## Batch.ID 0.1358061205
## Fault.flag 0.1114170518
## PC19
## Time..h. -0.064061981
## Aeration.rate.Fg.L.h. -0.335177188
## Sugar.feed.rate.Fs.L.h. -0.396774499
## Acid.flow.rate.Fa.L.h. 0.018041617
## Base.flow.rate.Fb.L.h. 0.013892162
## Heating.cooling.water.flow.rate.Fc.L.h. -0.076787044
## Heating.water.flow.rate.Fh.L.h. -0.085815869
## Water.for.injection.dilution.Fw.L.h. -0.127504826
## Air.head.pressure.pressure.bar. 0.414314092
## Dumped.broth.flow.Fremoved.L.h. 0.029158323
## Substrate.concentration.S.g.L. -0.160414292
## Dissolved.oxygen.concentration.DO2.mg.L. -0.280648806
## Penicillin.concentration.P.g.L. -0.126454396
## Vessel.Volume.V.L. 0.140256536
## Vessel.Weight.Wt.Kg. 0.106128889
## pH.pH.pH. -0.010977858
## Temperature.T.K. 0.030555712
## Generated.heat.Q.kJ. 0.219256045
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.453960480
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.045464978
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.020030104
## Oil.flow.Foil.L.hr. 0.028252851
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.032605591
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.117608033
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.078463196
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.027917646
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.056002735
## Carbon.evolution.rate.CER.g.h. 0.196229450
## Viscosity.Viscosity_offline.centPoise. 0.023571540
## X1.Raman.spec.recorded -0.127504826
## X2.PAT.control.PAT_ref.PAT.ref. -0.127504826
## Batch.reference.Batch_ref.Batch.ref. -0.127504826
## Batch.ID -0.002469697
## Fault.flag -0.029594081
## PC20
## Time..h. -0.058065110
## Aeration.rate.Fg.L.h. 0.001532730
## Sugar.feed.rate.Fs.L.h. -0.033877547
## Acid.flow.rate.Fa.L.h. 0.008689025
## Base.flow.rate.Fb.L.h. 0.004211067
## Heating.cooling.water.flow.rate.Fc.L.h. 0.005777409
## Heating.water.flow.rate.Fh.L.h. 0.003254063
## Water.for.injection.dilution.Fw.L.h. -0.016299917
## Air.head.pressure.pressure.bar. -0.038483814
## Dumped.broth.flow.Fremoved.L.h. 0.006655604
## Substrate.concentration.S.g.L. -0.044893258
## Dissolved.oxygen.concentration.DO2.mg.L. 0.004042720
## Penicillin.concentration.P.g.L. 0.052017022
## Vessel.Volume.V.L. 0.028371664
## Vessel.Weight.Wt.Kg. 0.022961486
## pH.pH.pH. -0.010729526
## Temperature.T.K. 0.023051873
## Generated.heat.Q.kJ. -0.088397475
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.116191137
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.012446484
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.328259255
## Oil.flow.Foil.L.hr. -0.001346367
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.049614265
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.024032327
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.024644259
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.466348552
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.790877509
## Carbon.evolution.rate.CER.g.h. 0.085525674
## Viscosity.Viscosity_offline.centPoise. -0.049217644
## X1.Raman.spec.recorded -0.016299917
## X2.PAT.control.PAT_ref.PAT.ref. -0.016299917
## Batch.reference.Batch_ref.Batch.ref. -0.016299917
## Batch.ID 0.019117420
## Fault.flag 0.009716809
## PC21
## Time..h. -1.121703e-01
## Aeration.rate.Fg.L.h. -1.758874e-01
## Sugar.feed.rate.Fs.L.h. -2.069655e-03
## Acid.flow.rate.Fa.L.h. -8.447166e-05
## Base.flow.rate.Fb.L.h. -9.115224e-05
## Heating.cooling.water.flow.rate.Fc.L.h. 1.114930e-02
## Heating.water.flow.rate.Fh.L.h. 1.773871e-03
## Water.for.injection.dilution.Fw.L.h. 3.221559e-02
## Air.head.pressure.pressure.bar. -2.867438e-02
## Dumped.broth.flow.Fremoved.L.h. 2.522958e-02
## Substrate.concentration.S.g.L. -8.089627e-02
## Dissolved.oxygen.concentration.DO2.mg.L. 5.834586e-02
## Penicillin.concentration.P.g.L. 1.919260e-01
## Vessel.Volume.V.L. 5.478297e-02
## Vessel.Weight.Wt.Kg. 3.849328e-02
## pH.pH.pH. 4.278644e-03
## Temperature.T.K. 1.850084e-02
## Generated.heat.Q.kJ. -6.754617e-02
## carbon.dioxide.percent.in.off.gas.CO2outgas... 1.768496e-02
## PAA.flow.Fpaa.PAA.flow..L.h.. -2.425657e-02
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -2.804814e-01
## Oil.flow.Foil.L.hr. 1.741453e-02
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 1.542981e-01
## Oxygen.Uptake.Rate.OUR..g.min...1... 3.165397e-01
## Oxygen.in.percent.in.off.gas.O2.O2...... 2.506273e-01
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 4.751024e-01
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 2.389011e-01
## Carbon.evolution.rate.CER.g.h. 8.092608e-02
## Viscosity.Viscosity_offline.centPoise. -5.808609e-01
## X1.Raman.spec.recorded 3.221559e-02
## X2.PAT.control.PAT_ref.PAT.ref. 3.221559e-02
## Batch.reference.Batch_ref.Batch.ref. 3.221559e-02
## Batch.ID -8.836214e-03
## Fault.flag 3.214699e-02
## PC22
## Time..h. -0.2133954733
## Aeration.rate.Fg.L.h. -0.2285876932
## Sugar.feed.rate.Fs.L.h. 0.0056679460
## Acid.flow.rate.Fa.L.h. -0.0059378756
## Base.flow.rate.Fb.L.h. -0.0002423424
## Heating.cooling.water.flow.rate.Fc.L.h. 0.0098614459
## Heating.water.flow.rate.Fh.L.h. 0.0069077212
## Water.for.injection.dilution.Fw.L.h. 0.0490201024
## Air.head.pressure.pressure.bar. -0.1585252142
## Dumped.broth.flow.Fremoved.L.h. 0.0391450339
## Substrate.concentration.S.g.L. -0.1551100249
## Dissolved.oxygen.concentration.DO2.mg.L. 0.1165830831
## Penicillin.concentration.P.g.L. 0.3616488642
## Vessel.Volume.V.L. 0.0337915493
## Vessel.Weight.Wt.Kg. 0.0215969732
## pH.pH.pH. 0.0031926911
## Temperature.T.K. 0.0115981179
## Generated.heat.Q.kJ. -0.0654634493
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.0943491538
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.0381357137
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.1468840956
## Oil.flow.Foil.L.hr. 0.0312430999
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.1015997370
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.4845546136
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.3729060397
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.3197153345
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.0870976421
## Carbon.evolution.rate.CER.g.h. 0.1881576951
## Viscosity.Viscosity_offline.centPoise. 0.3586798287
## X1.Raman.spec.recorded 0.0490201024
## X2.PAT.control.PAT_ref.PAT.ref. 0.0490201024
## Batch.reference.Batch_ref.Batch.ref. 0.0490201024
## Batch.ID 0.0032561035
## Fault.flag 0.0171251856
## PC23
## Time..h. 0.208243312
## Aeration.rate.Fg.L.h. -0.250152247
## Sugar.feed.rate.Fs.L.h. -0.092749004
## Acid.flow.rate.Fa.L.h. -0.011063729
## Base.flow.rate.Fb.L.h. 0.013004355
## Heating.cooling.water.flow.rate.Fc.L.h. -0.032383617
## Heating.water.flow.rate.Fh.L.h. -0.018774474
## Water.for.injection.dilution.Fw.L.h. 0.066427881
## Air.head.pressure.pressure.bar. 0.265682697
## Dumped.broth.flow.Fremoved.L.h. -0.028746209
## Substrate.concentration.S.g.L. 0.177299283
## Dissolved.oxygen.concentration.DO2.mg.L. -0.070208832
## Penicillin.concentration.P.g.L. -0.158479420
## Vessel.Volume.V.L. -0.098038119
## Vessel.Weight.Wt.Kg. -0.077444682
## pH.pH.pH. -0.006685680
## Temperature.T.K. -0.123467194
## Generated.heat.Q.kJ. 0.494759391
## carbon.dioxide.percent.in.off.gas.CO2outgas... -0.408438594
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.008978641
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.077521453
## Oil.flow.Foil.L.hr. 0.009542347
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.012033325
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.314550212
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.215844211
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.064955109
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.160987493
## Carbon.evolution.rate.CER.g.h. -0.325977733
## Viscosity.Viscosity_offline.centPoise. 0.029967834
## X1.Raman.spec.recorded 0.066427881
## X2.PAT.control.PAT_ref.PAT.ref. 0.066427881
## Batch.reference.Batch_ref.Batch.ref. 0.066427881
## Batch.ID -0.039373269
## Fault.flag 0.003109683
## PC24
## Time..h. 0.059939764
## Aeration.rate.Fg.L.h. -0.119488605
## Sugar.feed.rate.Fs.L.h. -0.012533450
## Acid.flow.rate.Fa.L.h. -0.001594851
## Base.flow.rate.Fb.L.h. -0.006441692
## Heating.cooling.water.flow.rate.Fc.L.h. 0.036318771
## Heating.water.flow.rate.Fh.L.h. 0.041747411
## Water.for.injection.dilution.Fw.L.h. 0.077452183
## Air.head.pressure.pressure.bar. 0.584983441
## Dumped.broth.flow.Fremoved.L.h. -0.008751749
## Substrate.concentration.S.g.L. 0.105249651
## Dissolved.oxygen.concentration.DO2.mg.L. -0.113185519
## Penicillin.concentration.P.g.L. 0.039507229
## Vessel.Volume.V.L. 0.013691104
## Vessel.Weight.Wt.Kg. 0.014062644
## pH.pH.pH. -0.003061390
## Temperature.T.K. 0.150373359
## Generated.heat.Q.kJ. -0.706223207
## carbon.dioxide.percent.in.off.gas.CO2outgas... -0.196553049
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.005765153
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.022294453
## Oil.flow.Foil.L.hr. 0.000734295
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.013486538
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.004411432
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.087417459
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.040218901
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.018044371
## Carbon.evolution.rate.CER.g.h. -0.101766751
## Viscosity.Viscosity_offline.centPoise. 0.048338691
## X1.Raman.spec.recorded 0.077452183
## X2.PAT.control.PAT_ref.PAT.ref. 0.077452183
## Batch.reference.Batch_ref.Batch.ref. 0.077452183
## Batch.ID 0.058001656
## Fault.flag -0.019348019
## PC25
## Time..h. 0.436409041
## Aeration.rate.Fg.L.h. -0.078803225
## Sugar.feed.rate.Fs.L.h. -0.002364755
## Acid.flow.rate.Fa.L.h. -0.002494114
## Base.flow.rate.Fb.L.h. -0.005551966
## Heating.cooling.water.flow.rate.Fc.L.h. 0.006544252
## Heating.water.flow.rate.Fh.L.h. 0.007183061
## Water.for.injection.dilution.Fw.L.h. 0.009751467
## Air.head.pressure.pressure.bar. -0.215480958
## Dumped.broth.flow.Fremoved.L.h. -0.015972526
## Substrate.concentration.S.g.L. 0.337523230
## Dissolved.oxygen.concentration.DO2.mg.L. 0.093139358
## Penicillin.concentration.P.g.L. -0.475968707
## Vessel.Volume.V.L. -0.206178884
## Vessel.Weight.Wt.Kg. -0.119432655
## pH.pH.pH. -0.006491864
## Temperature.T.K. 0.057716613
## Generated.heat.Q.kJ. -0.224537504
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.437484672
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.009759106
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.001137262
## Oil.flow.Foil.L.hr. 0.011354706
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.004196004
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.231717622
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.196556763
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.004296299
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.002711113
## Carbon.evolution.rate.CER.g.h. 0.101822172
## Viscosity.Viscosity_offline.centPoise. -0.001402599
## X1.Raman.spec.recorded 0.009751467
## X2.PAT.control.PAT_ref.PAT.ref. 0.009751467
## Batch.reference.Batch_ref.Batch.ref. 0.009751467
## Batch.ID -0.022846691
## Fault.flag 0.039295921
## PC26
## Time..h. 0.0163475520
## Aeration.rate.Fg.L.h. -0.0135959358
## Sugar.feed.rate.Fs.L.h. 0.0019256005
## Acid.flow.rate.Fa.L.h. -0.0018061256
## Base.flow.rate.Fb.L.h. 0.0024028478
## Heating.cooling.water.flow.rate.Fc.L.h. 0.0051744514
## Heating.water.flow.rate.Fh.L.h. 0.0023962589
## Water.for.injection.dilution.Fw.L.h. 0.0061026013
## Air.head.pressure.pressure.bar. -0.0466665552
## Dumped.broth.flow.Fremoved.L.h. -0.0015968624
## Substrate.concentration.S.g.L. 0.0212934496
## Dissolved.oxygen.concentration.DO2.mg.L. 0.0160340889
## Penicillin.concentration.P.g.L. -0.0130292716
## Vessel.Volume.V.L. -0.0166311821
## Vessel.Weight.Wt.Kg. -0.0118725001
## pH.pH.pH. -0.0001319993
## Temperature.T.K. -0.0110039234
## Generated.heat.Q.kJ. 0.0384582203
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.0089521956
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.0015448749
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.0076227945
## Oil.flow.Foil.L.hr. 0.0099876928
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.0048210714
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.0298617221
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.0170079209
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.0118587347
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.0067320848
## Carbon.evolution.rate.CER.g.h. 0.0050325625
## Viscosity.Viscosity_offline.centPoise. -0.0157794000
## X1.Raman.spec.recorded 0.0061026013
## X2.PAT.control.PAT_ref.PAT.ref. 0.0061026013
## Batch.reference.Batch_ref.Batch.ref. 0.0061026013
## Batch.ID 0.7009285919
## Fault.flag -0.7078627166
## PC27
## Time..h. 3.824358e-01
## Aeration.rate.Fg.L.h. -2.144494e-02
## Sugar.feed.rate.Fs.L.h. 8.181761e-03
## Acid.flow.rate.Fa.L.h. 3.850820e-04
## Base.flow.rate.Fb.L.h. -2.032307e-03
## Heating.cooling.water.flow.rate.Fc.L.h. -4.750016e-04
## Heating.water.flow.rate.Fh.L.h. 4.749223e-05
## Water.for.injection.dilution.Fw.L.h. 1.761230e-01
## Air.head.pressure.pressure.bar. -3.459291e-02
## Dumped.broth.flow.Fremoved.L.h. -5.273818e-04
## Substrate.concentration.S.g.L. -7.816838e-01
## Dissolved.oxygen.concentration.DO2.mg.L. 5.685468e-04
## Penicillin.concentration.P.g.L. -2.588258e-01
## Vessel.Volume.V.L. 2.466527e-02
## Vessel.Weight.Wt.Kg. -3.034104e-02
## pH.pH.pH. -1.735305e-04
## Temperature.T.K. 8.629823e-03
## Generated.heat.Q.kJ. -3.206117e-02
## carbon.dioxide.percent.in.off.gas.CO2outgas... -1.344806e-01
## PAA.flow.Fpaa.PAA.flow..L.h.. -3.283869e-03
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 3.728299e-03
## Oil.flow.Foil.L.hr. 4.956661e-03
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -1.403133e-03
## Oxygen.Uptake.Rate.OUR..g.min...1... -2.111932e-02
## Oxygen.in.percent.in.off.gas.O2.O2...... -9.939939e-03
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 3.047424e-03
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -7.493784e-03
## Carbon.evolution.rate.CER.g.h. 1.688498e-01
## Viscosity.Viscosity_offline.centPoise. 2.164928e-03
## X1.Raman.spec.recorded 1.761230e-01
## X2.PAT.control.PAT_ref.PAT.ref. 1.761230e-01
## Batch.reference.Batch_ref.Batch.ref. 1.761230e-01
## Batch.ID 4.883384e-03
## Fault.flag 7.663584e-05
## PC28
## Time..h. 2.691022e-01
## Aeration.rate.Fg.L.h. 5.700884e-02
## Sugar.feed.rate.Fs.L.h. 9.354123e-03
## Acid.flow.rate.Fa.L.h. -4.440018e-05
## Base.flow.rate.Fb.L.h. -1.691743e-04
## Heating.cooling.water.flow.rate.Fc.L.h. 6.437068e-04
## Heating.water.flow.rate.Fh.L.h. 8.952013e-04
## Water.for.injection.dilution.Fw.L.h. -2.189527e-02
## Air.head.pressure.pressure.bar. -2.008607e-02
## Dumped.broth.flow.Fremoved.L.h. -1.008390e-03
## Substrate.concentration.S.g.L. -2.330149e-01
## Dissolved.oxygen.concentration.DO2.mg.L. 8.219678e-03
## Penicillin.concentration.P.g.L. 3.210617e-01
## Vessel.Volume.V.L. 1.855518e-02
## Vessel.Weight.Wt.Kg. 4.831416e-02
## pH.pH.pH. -1.037851e-03
## Temperature.T.K. 8.279291e-03
## Generated.heat.Q.kJ. -3.313066e-02
## carbon.dioxide.percent.in.off.gas.CO2outgas... 4.231488e-01
## PAA.flow.Fpaa.PAA.flow..L.h.. 2.777682e-03
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -5.412042e-04
## Oil.flow.Foil.L.hr. -1.062298e-03
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 4.383784e-04
## Oxygen.Uptake.Rate.OUR..g.min...1... 2.013715e-02
## Oxygen.in.percent.in.off.gas.O2.O2...... 2.074701e-02
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -1.411651e-03
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 6.170625e-04
## Carbon.evolution.rate.CER.g.h. -7.620279e-01
## Viscosity.Viscosity_offline.centPoise. 8.691441e-04
## X1.Raman.spec.recorded -2.189527e-02
## X2.PAT.control.PAT_ref.PAT.ref. -2.189527e-02
## Batch.reference.Batch_ref.Batch.ref. -2.189527e-02
## Batch.ID 3.213801e-03
## Fault.flag -5.756874e-03
## PC29
## Time..h. 6.120532e-01
## Aeration.rate.Fg.L.h. -4.064618e-02
## Sugar.feed.rate.Fs.L.h. 1.577747e-03
## Acid.flow.rate.Fa.L.h. -1.214094e-04
## Base.flow.rate.Fb.L.h. 2.776379e-04
## Heating.cooling.water.flow.rate.Fc.L.h. 1.301870e-03
## Heating.water.flow.rate.Fh.L.h. 9.975399e-04
## Water.for.injection.dilution.Fw.L.h. -2.672830e-01
## Air.head.pressure.pressure.bar. -1.025727e-03
## Dumped.broth.flow.Fremoved.L.h. 2.712013e-04
## Substrate.concentration.S.g.L. 1.754361e-02
## Dissolved.oxygen.concentration.DO2.mg.L. 1.680678e-04
## Penicillin.concentration.P.g.L. 4.152638e-01
## Vessel.Volume.V.L. -1.035103e-01
## Vessel.Weight.Wt.Kg. 1.246625e-01
## pH.pH.pH. 1.473822e-04
## Temperature.T.K. 1.527968e-03
## Generated.heat.Q.kJ. -8.467692e-03
## carbon.dioxide.percent.in.off.gas.CO2outgas... -2.374002e-01
## PAA.flow.Fpaa.PAA.flow..L.h.. -5.663866e-05
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -1.800678e-03
## Oil.flow.Foil.L.hr. -1.538917e-03
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 1.018162e-03
## Oxygen.Uptake.Rate.OUR..g.min...1... -5.683822e-03
## Oxygen.in.percent.in.off.gas.O2.O2...... -3.969260e-03
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 9.530681e-04
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 5.998780e-04
## Carbon.evolution.rate.CER.g.h. 2.871709e-01
## Viscosity.Viscosity_offline.centPoise. -8.413957e-04
## X1.Raman.spec.recorded -2.672830e-01
## X2.PAT.control.PAT_ref.PAT.ref. -2.672830e-01
## Batch.reference.Batch_ref.Batch.ref. -2.672830e-01
## Batch.ID -9.883312e-05
## Fault.flag -2.819672e-03
## PC30
## Time..h. 1.230256e-01
## Aeration.rate.Fg.L.h. 7.877497e-04
## Sugar.feed.rate.Fs.L.h. -6.628802e-05
## Acid.flow.rate.Fa.L.h. -2.229730e-06
## Base.flow.rate.Fb.L.h. 1.545568e-05
## Heating.cooling.water.flow.rate.Fc.L.h. 3.186020e-05
## Heating.water.flow.rate.Fh.L.h. 2.080165e-05
## Water.for.injection.dilution.Fw.L.h. -3.410205e-02
## Air.head.pressure.pressure.bar. 5.688225e-04
## Dumped.broth.flow.Fremoved.L.h. 6.714456e-05
## Substrate.concentration.S.g.L. 5.618848e-02
## Dissolved.oxygen.concentration.DO2.mg.L. -2.800477e-04
## Penicillin.concentration.P.g.L. 8.938592e-02
## Vessel.Volume.V.L. 6.068336e-01
## Vessel.Weight.Wt.Kg. -7.741786e-01
## pH.pH.pH. -2.906766e-05
## Temperature.T.K. 2.697188e-05
## Generated.heat.Q.kJ. -1.591079e-04
## carbon.dioxide.percent.in.off.gas.CO2outgas... 2.143558e-03
## PAA.flow.Fpaa.PAA.flow..L.h.. -7.864233e-05
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -1.201987e-02
## Oil.flow.Foil.L.hr. -8.170999e-05
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 4.732881e-03
## Oxygen.Uptake.Rate.OUR..g.min...1... -1.054041e-03
## Oxygen.in.percent.in.off.gas.O2.O2...... -1.002596e-03
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 2.992592e-03
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -3.543366e-03
## Carbon.evolution.rate.CER.g.h. 3.472656e-02
## Viscosity.Viscosity_offline.centPoise. 8.008736e-03
## X1.Raman.spec.recorded -3.410205e-02
## X2.PAT.control.PAT_ref.PAT.ref. -3.410205e-02
## Batch.reference.Batch_ref.Batch.ref. -3.410205e-02
## Batch.ID -3.689382e-04
## Fault.flag 2.077603e-04
## PC31
## Time..h. 2.934142e-03
## Aeration.rate.Fg.L.h. -6.526325e-06
## Sugar.feed.rate.Fs.L.h. 9.905780e-06
## Acid.flow.rate.Fa.L.h. -5.206202e-07
## Base.flow.rate.Fb.L.h. -7.790127e-07
## Heating.cooling.water.flow.rate.Fc.L.h. 4.514214e-06
## Heating.water.flow.rate.Fh.L.h. 9.917268e-06
## Water.for.injection.dilution.Fw.L.h. -8.834319e-04
## Air.head.pressure.pressure.bar. 3.081947e-05
## Dumped.broth.flow.Fremoved.L.h. -1.386713e-06
## Substrate.concentration.S.g.L. 7.550015e-04
## Dissolved.oxygen.concentration.DO2.mg.L. -4.634964e-06
## Penicillin.concentration.P.g.L. 2.122122e-03
## Vessel.Volume.V.L. 9.518125e-03
## Vessel.Weight.Wt.Kg. -1.211968e-02
## pH.pH.pH. -1.713164e-06
## Temperature.T.K. 1.722041e-05
## Generated.heat.Q.kJ. -9.863655e-05
## carbon.dioxide.percent.in.off.gas.CO2outgas... -4.164241e-05
## PAA.flow.Fpaa.PAA.flow..L.h.. -7.435965e-07
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 7.576183e-01
## Oil.flow.Foil.L.hr. -3.697291e-06
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -2.979014e-01
## Oxygen.Uptake.Rate.OUR..g.min...1... -1.630360e-05
## Oxygen.in.percent.in.off.gas.O2.O2...... -6.535956e-06
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -1.838119e-01
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 2.188254e-01
## Carbon.evolution.rate.CER.g.h. 4.753065e-04
## Viscosity.Viscosity_offline.centPoise. -5.053152e-01
## X1.Raman.spec.recorded -8.834319e-04
## X2.PAT.control.PAT_ref.PAT.ref. -8.834319e-04
## Batch.reference.Batch_ref.Batch.ref. -8.834319e-04
## Batch.ID -3.937741e-05
## Fault.flag 3.452151e-05
## PC32
## Time..h. 0.000000e+00
## Aeration.rate.Fg.L.h. -1.498688e-16
## Sugar.feed.rate.Fs.L.h. -3.706439e-16
## Acid.flow.rate.Fa.L.h. -7.394726e-17
## Base.flow.rate.Fb.L.h. -2.489914e-16
## Heating.cooling.water.flow.rate.Fc.L.h. -3.518133e-17
## Heating.water.flow.rate.Fh.L.h. -2.343877e-16
## Water.for.injection.dilution.Fw.L.h. 8.367269e-01
## Air.head.pressure.pressure.bar. 1.739256e-15
## Dumped.broth.flow.Fremoved.L.h. -9.048135e-17
## Substrate.concentration.S.g.L. -5.571068e-15
## Dissolved.oxygen.concentration.DO2.mg.L. -6.259118e-16
## Penicillin.concentration.P.g.L. 7.821862e-16
## Vessel.Volume.V.L. -3.608621e-14
## Vessel.Weight.Wt.Kg. 4.708056e-14
## pH.pH.pH. 6.190816e-17
## Temperature.T.K. -1.114858e-16
## Generated.heat.Q.kJ. -1.605760e-16
## carbon.dioxide.percent.in.off.gas.CO2outgas... -4.699472e-16
## PAA.flow.Fpaa.PAA.flow..L.h.. 1.459155e-16
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 3.770295e-12
## Oil.flow.Foil.L.hr. 1.050414e-16
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -1.482530e-12
## Oxygen.Uptake.Rate.OUR..g.min...1... -5.100206e-16
## Oxygen.in.percent.in.off.gas.O2.O2...... -3.269461e-16
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -9.148009e-13
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 1.089148e-12
## Carbon.evolution.rate.CER.g.h. -6.431984e-15
## Viscosity.Viscosity_offline.centPoise. -2.514762e-12
## X1.Raman.spec.recorded -3.846765e-01
## X2.PAT.control.PAT_ref.PAT.ref. -3.837230e-01
## Batch.reference.Batch_ref.Batch.ref. -6.832739e-02
## Batch.ID -1.038671e-16
## Fault.flag 3.278719e-17
## PC33
## Time..h. 0.000000e+00
## Aeration.rate.Fg.L.h. -1.204279e-15
## Sugar.feed.rate.Fs.L.h. 1.973128e-16
## Acid.flow.rate.Fa.L.h. -7.312851e-17
## Base.flow.rate.Fb.L.h. 1.797150e-21
## Heating.cooling.water.flow.rate.Fc.L.h. 1.159654e-16
## Heating.water.flow.rate.Fh.L.h. 1.119529e-16
## Water.for.injection.dilution.Fw.L.h. -2.233557e-01
## Air.head.pressure.pressure.bar. -7.618639e-16
## Dumped.broth.flow.Fremoved.L.h. 9.378234e-17
## Substrate.concentration.S.g.L. 4.408421e-15
## Dissolved.oxygen.concentration.DO2.mg.L. 3.928159e-16
## Penicillin.concentration.P.g.L. -1.915343e-15
## Vessel.Volume.V.L. -1.722016e-15
## Vessel.Weight.Wt.Kg. 6.678049e-16
## pH.pH.pH. 2.766393e-17
## Temperature.T.K. -1.338515e-17
## Generated.heat.Q.kJ. 2.510971e-16
## carbon.dioxide.percent.in.off.gas.CO2outgas... -1.043119e-14
## PAA.flow.Fpaa.PAA.flow..L.h.. -2.765311e-17
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -7.424537e-15
## Oil.flow.Foil.L.hr. -1.592945e-16
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 2.941881e-15
## Oxygen.Uptake.Rate.OUR..g.min...1... -3.931970e-16
## Oxygen.in.percent.in.off.gas.O2.O2...... -7.760695e-16
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 1.854898e-15
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -2.157885e-15
## Carbon.evolution.rate.CER.g.h. 1.879174e-14
## Viscosity.Viscosity_offline.centPoise. 4.901706e-15
## X1.Raman.spec.recorded -3.201159e-01
## X2.PAT.control.PAT_ref.PAT.ref. -3.198542e-01
## Batch.reference.Batch_ref.Batch.ref. 8.633258e-01
## Batch.ID -2.542415e-17
## Fault.flag 8.601645e-17
## PC34
## Time..h. 0.000000e+00
## Aeration.rate.Fg.L.h. 2.571851e-17
## Sugar.feed.rate.Fs.L.h. 5.946915e-18
## Acid.flow.rate.Fa.L.h. -5.173532e-18
## Base.flow.rate.Fb.L.h. -3.058193e-18
## Heating.cooling.water.flow.rate.Fc.L.h. -7.152643e-18
## Heating.water.flow.rate.Fh.L.h. 4.137743e-18
## Water.for.injection.dilution.Fw.L.h. 5.227952e-04
## Air.head.pressure.pressure.bar. -2.431983e-17
## Dumped.broth.flow.Fremoved.L.h. -2.237613e-18
## Substrate.concentration.S.g.L. 2.519063e-17
## Dissolved.oxygen.concentration.DO2.mg.L. 6.201101e-18
## Penicillin.concentration.P.g.L. 4.410411e-17
## Vessel.Volume.V.L. -1.490021e-17
## Vessel.Weight.Wt.Kg. 2.172133e-17
## pH.pH.pH. -3.075932e-18
## Temperature.T.K. -1.400779e-17
## Generated.heat.Q.kJ. 4.947761e-17
## carbon.dioxide.percent.in.off.gas.CO2outgas... 3.841938e-18
## PAA.flow.Fpaa.PAA.flow..L.h.. -8.899245e-19
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 5.209848e-17
## Oil.flow.Foil.L.hr. -1.294054e-18
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -7.213155e-18
## Oxygen.Uptake.Rate.OUR..g.min...1... 9.229549e-18
## Oxygen.in.percent.in.off.gas.O2.O2...... 4.620471e-18
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -2.450539e-17
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 2.887713e-19
## Carbon.evolution.rate.CER.g.h. 1.251348e-17
## Viscosity.Viscosity_offline.centPoise. -1.908258e-17
## X1.Raman.spec.recorded 7.067884e-01
## X2.PAT.control.PAT_ref.PAT.ref. -7.074248e-01
## Batch.reference.Batch_ref.Batch.ref. 1.136656e-04
## Batch.ID 3.217869e-18
## Fault.flag 7.014259e-18pca <- prcomp(Penicillin_scaled, scale = T)pca$sdev## [1] 4.358686e+00 2.205296e+00 2.100134e+00 1.418142e+00 1.166698e+00
## [6] 8.085847e-01 6.500733e-01 5.784470e-01 5.028894e-01 4.349995e-01
## [11] 3.567104e-01 3.350405e-01 2.712734e-01 2.447796e-01 2.091135e-01
## [16] 1.934269e-01 1.381817e-01 1.366587e-01 6.953700e-02 4.144815e-02
## [21] 3.368249e-02 3.240153e-02 2.995979e-02 2.311646e-02 1.546378e-02
## [26] 1.363907e-02 3.017046e-03 1.505562e-03 7.818226e-04 5.366227e-05
## [31] 1.367838e-05 4.210701e-16 4.210701e-16 4.210701e-16pca$sdev^2## [1] 1.899815e+01 4.863329e+00 4.410565e+00 2.011128e+00 1.361185e+00
## [6] 6.538093e-01 4.225952e-01 3.346009e-01 2.528977e-01 1.892245e-01
## [11] 1.272423e-01 1.122522e-01 7.358924e-02 5.991706e-02 4.372847e-02
## [16] 3.741396e-02 1.909417e-02 1.867559e-02 4.835394e-03 1.717949e-03
## [21] 1.134510e-03 1.049859e-03 8.975892e-04 5.343709e-04 2.391284e-04
## [26] 1.860244e-04 9.102565e-06 2.266718e-06 6.112465e-07 2.879639e-09
## [31] 1.870981e-10 1.773000e-31 1.773000e-31 1.773000e-31pca$rotation## PC1
## Time..h. 0.22770584
## Aeration.rate.Fg.L.h. 0.21625494
## Sugar.feed.rate.Fs.L.h. 0.18791620
## Acid.flow.rate.Fa.L.h. 0.04524415
## Base.flow.rate.Fb.L.h. -0.16832698
## Heating.cooling.water.flow.rate.Fc.L.h. -0.13267186
## Heating.water.flow.rate.Fh.L.h. 0.10860797
## Water.for.injection.dilution.Fw.L.h. 0.22839846
## Air.head.pressure.pressure.bar. 0.22084594
## Dumped.broth.flow.Fremoved.L.h. -0.05818216
## Substrate.concentration.S.g.L. 0.22820718
## Dissolved.oxygen.concentration.DO2.mg.L. 0.01699940
## Penicillin.concentration.P.g.L. 0.22811631
## Vessel.Volume.V.L. 0.22492886
## Vessel.Weight.Wt.Kg. 0.22609929
## pH.pH.pH. 0.04783488
## Temperature.T.K. -0.12103745
## Generated.heat.Q.kJ. 0.22089665
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.21999985
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.16183831
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.03279132
## Oil.flow.Foil.L.hr. -0.17494631
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.02621682
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.10089045
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.10026949
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.03656895
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.03441640
## Carbon.evolution.rate.CER.g.h. 0.22463193
## Viscosity.Viscosity_offline.centPoise. 0.03531000
## X1.Raman.spec.recorded 0.22839846
## X2.PAT.control.PAT_ref.PAT.ref. 0.22839846
## Batch.reference.Batch_ref.Batch.ref. 0.22839846
## Batch.ID 0.21474923
## Fault.flag 0.21466435
## PC2
## Time..h. -0.013569704
## Aeration.rate.Fg.L.h. -0.017540578
## Sugar.feed.rate.Fs.L.h. -0.021410561
## Acid.flow.rate.Fa.L.h. -0.043978179
## Base.flow.rate.Fb.L.h. 0.006316711
## Heating.cooling.water.flow.rate.Fc.L.h. 0.003390360
## Heating.water.flow.rate.Fh.L.h. 0.009200547
## Water.for.injection.dilution.Fw.L.h. -0.016036621
## Air.head.pressure.pressure.bar. -0.019063856
## Dumped.broth.flow.Fremoved.L.h. 0.049567917
## Substrate.concentration.S.g.L. -0.013083921
## Dissolved.oxygen.concentration.DO2.mg.L. 0.015731993
## Penicillin.concentration.P.g.L. -0.020242944
## Vessel.Volume.V.L. -0.005733205
## Vessel.Weight.Wt.Kg. -0.008072996
## pH.pH.pH. -0.058057137
## Temperature.T.K. 0.014709574
## Generated.heat.Q.kJ. -0.015241275
## carbon.dioxide.percent.in.off.gas.CO2outgas... -0.020927617
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.004138840
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.447758597
## Oil.flow.Foil.L.hr. 0.002757476
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.437072868
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.006296079
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.005729786
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.443015637
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.446674806
## Carbon.evolution.rate.CER.g.h. -0.019762235
## Viscosity.Viscosity_offline.centPoise. 0.445935164
## X1.Raman.spec.recorded -0.016036621
## X2.PAT.control.PAT_ref.PAT.ref. -0.016036621
## Batch.reference.Batch_ref.Batch.ref. -0.016036621
## Batch.ID -0.025455344
## Fault.flag -0.025518573
## PC3
## Time..h. 0.041384471
## Aeration.rate.Fg.L.h. 0.136324640
## Sugar.feed.rate.Fs.L.h. 0.223741196
## Acid.flow.rate.Fa.L.h. -0.040044762
## Base.flow.rate.Fb.L.h. 0.213223346
## Heating.cooling.water.flow.rate.Fc.L.h. 0.318861006
## Heating.water.flow.rate.Fh.L.h. 0.003051813
## Water.for.injection.dilution.Fw.L.h. 0.024745266
## Air.head.pressure.pressure.bar. 0.099547498
## Dumped.broth.flow.Fremoved.L.h. -0.026474207
## Substrate.concentration.S.g.L. 0.019268374
## Dissolved.oxygen.concentration.DO2.mg.L. -0.457431998
## Penicillin.concentration.P.g.L. 0.025483280
## Vessel.Volume.V.L. 0.033832170
## Vessel.Weight.Wt.Kg. 0.037844554
## pH.pH.pH. -0.048330696
## Temperature.T.K. -0.014311294
## Generated.heat.Q.kJ. 0.065956997
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.127908123
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.272002435
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.010727245
## Oil.flow.Foil.L.hr. 0.273698652
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.004999218
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.418614101
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.419555604
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.014679296
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.017593882
## Carbon.evolution.rate.CER.g.h. 0.091467641
## Viscosity.Viscosity_offline.centPoise. 0.015415293
## X1.Raman.spec.recorded 0.024745266
## X2.PAT.control.PAT_ref.PAT.ref. 0.024745266
## Batch.reference.Batch_ref.Batch.ref. 0.024745266
## Batch.ID 0.105283003
## Fault.flag 0.105952543
## PC4
## Time..h. 0.0376662634
## Aeration.rate.Fg.L.h. 0.0195751907
## Sugar.feed.rate.Fs.L.h. 0.0154334884
## Acid.flow.rate.Fa.L.h. -0.5343101828
## Base.flow.rate.Fb.L.h. 0.0671366580
## Heating.cooling.water.flow.rate.Fc.L.h. -0.0181085452
## Heating.water.flow.rate.Fh.L.h. -0.0970143633
## Water.for.injection.dilution.Fw.L.h. 0.0228744673
## Air.head.pressure.pressure.bar. 0.0194621614
## Dumped.broth.flow.Fremoved.L.h. 0.5188019939
## Substrate.concentration.S.g.L. 0.0375775332
## Dissolved.oxygen.concentration.DO2.mg.L. 0.0598165813
## Penicillin.concentration.P.g.L. 0.0008449866
## Vessel.Volume.V.L. 0.0531046332
## Vessel.Weight.Wt.Kg. 0.0468210063
## pH.pH.pH. -0.6234959038
## Temperature.T.K. -0.1263224650
## Generated.heat.Q.kJ. -0.0096524075
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.0046185345
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.0036456960
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.0379010332
## Oil.flow.Foil.L.hr. -0.0089061164
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.0482690105
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.0550879319
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.0318492482
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.0290159828
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.0315018085
## Carbon.evolution.rate.CER.g.h. 0.0065998913
## Viscosity.Viscosity_offline.centPoise. -0.0314555190
## X1.Raman.spec.recorded 0.0228744673
## X2.PAT.control.PAT_ref.PAT.ref. 0.0228744673
## Batch.reference.Batch_ref.Batch.ref. 0.0228744673
## Batch.ID 0.0222688640
## Fault.flag 0.0224685888
## PC5
## Time..h. -0.006533934
## Aeration.rate.Fg.L.h. 0.007501678
## Sugar.feed.rate.Fs.L.h. -0.014524099
## Acid.flow.rate.Fa.L.h. -0.184566780
## Base.flow.rate.Fb.L.h. 0.014129155
## Heating.cooling.water.flow.rate.Fc.L.h. -0.095407998
## Heating.water.flow.rate.Fh.L.h. 0.699218207
## Water.for.injection.dilution.Fw.L.h. -0.008585032
## Air.head.pressure.pressure.bar. 0.005740708
## Dumped.broth.flow.Fremoved.L.h. 0.005576110
## Substrate.concentration.S.g.L. -0.007676034
## Dissolved.oxygen.concentration.DO2.mg.L. 0.025758154
## Penicillin.concentration.P.g.L. -0.010752247
## Vessel.Volume.V.L. 0.002847072
## Vessel.Weight.Wt.Kg. 0.000569354
## pH.pH.pH. -0.074736660
## Temperature.T.K. 0.653248431
## Generated.heat.Q.kJ. 0.171725273
## carbon.dioxide.percent.in.off.gas.CO2outgas... -0.008406209
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.051243973
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.013371214
## Oil.flow.Foil.L.hr. 0.021286928
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.020697243
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.011592422
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.013050378
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.007890513
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.011115631
## Carbon.evolution.rate.CER.g.h. -0.007356829
## Viscosity.Viscosity_offline.centPoise. -0.009788268
## X1.Raman.spec.recorded -0.008585032
## X2.PAT.control.PAT_ref.PAT.ref. -0.008585032
## Batch.reference.Batch_ref.Batch.ref. -0.008585032
## Batch.ID -0.002087435
## Fault.flag -0.001048552
## PC6
## Time..h. 0.012458598
## Aeration.rate.Fg.L.h. 0.019927517
## Sugar.feed.rate.Fs.L.h. 0.084001301
## Acid.flow.rate.Fa.L.h. 0.634501845
## Base.flow.rate.Fb.L.h. 0.064712581
## Heating.cooling.water.flow.rate.Fc.L.h. -0.153236637
## Heating.water.flow.rate.Fh.L.h. 0.173034518
## Water.for.injection.dilution.Fw.L.h. 0.004005011
## Air.head.pressure.pressure.bar. 0.032693183
## Dumped.broth.flow.Fremoved.L.h. 0.715680253
## Substrate.concentration.S.g.L. 0.006870687
## Dissolved.oxygen.concentration.DO2.mg.L. -0.055869896
## Penicillin.concentration.P.g.L. -0.003182546
## Vessel.Volume.V.L. -0.068273056
## Vessel.Weight.Wt.Kg. -0.052058357
## pH.pH.pH. 0.026955826
## Temperature.T.K. -0.034326417
## Generated.heat.Q.kJ. 0.009117316
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.006030151
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.007906023
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.001674480
## Oil.flow.Foil.L.hr. 0.046047373
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.003203402
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.024550490
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.033104113
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.004287098
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.003917991
## Carbon.evolution.rate.CER.g.h. -0.002009488
## Viscosity.Viscosity_offline.centPoise. -0.004535153
## X1.Raman.spec.recorded 0.004005011
## X2.PAT.control.PAT_ref.PAT.ref. 0.004005011
## Batch.reference.Batch_ref.Batch.ref. 0.004005011
## Batch.ID -0.033304345
## Fault.flag -0.034942561
## PC7
## Time..h. -0.014718396
## Aeration.rate.Fg.L.h. -0.055232713
## Sugar.feed.rate.Fs.L.h. 0.214304503
## Acid.flow.rate.Fa.L.h. -0.238481494
## Base.flow.rate.Fb.L.h. 0.533011470
## Heating.cooling.water.flow.rate.Fc.L.h. -0.465634085
## Heating.water.flow.rate.Fh.L.h. 0.209563544
## Water.for.injection.dilution.Fw.L.h. -0.021613684
## Air.head.pressure.pressure.bar. 0.017661664
## Dumped.broth.flow.Fremoved.L.h. -0.053836315
## Substrate.concentration.S.g.L. -0.022671093
## Dissolved.oxygen.concentration.DO2.mg.L. -0.096595287
## Penicillin.concentration.P.g.L. -0.027833286
## Vessel.Volume.V.L. 0.029830922
## Vessel.Weight.Wt.Kg. 0.020709369
## pH.pH.pH. 0.226972701
## Temperature.T.K. -0.289273760
## Generated.heat.Q.kJ. -0.092361113
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.037573124
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.332611670
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.007227411
## Oil.flow.Foil.L.hr. -0.023273001
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.054257925
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.102995435
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.082540951
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.024543966
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.011734992
## Carbon.evolution.rate.CER.g.h. 0.015078019
## Viscosity.Viscosity_offline.centPoise. -0.017300672
## X1.Raman.spec.recorded -0.021613684
## X2.PAT.control.PAT_ref.PAT.ref. -0.021613684
## Batch.reference.Batch_ref.Batch.ref. -0.021613684
## Batch.ID -0.164640331
## Fault.flag -0.164261585
## PC8
## Time..h. 0.061508759
## Aeration.rate.Fg.L.h. 0.133183113
## Sugar.feed.rate.Fs.L.h. -0.075722633
## Acid.flow.rate.Fa.L.h. -0.145875251
## Base.flow.rate.Fb.L.h. 0.398866829
## Heating.cooling.water.flow.rate.Fc.L.h. 0.468240103
## Heating.water.flow.rate.Fh.L.h. -0.244972633
## Water.for.injection.dilution.Fw.L.h. 0.057315094
## Air.head.pressure.pressure.bar. 0.023639184
## Dumped.broth.flow.Fremoved.L.h. 0.277077211
## Substrate.concentration.S.g.L. 0.061681911
## Dissolved.oxygen.concentration.DO2.mg.L. 0.036602678
## Penicillin.concentration.P.g.L. 0.044137078
## Vessel.Volume.V.L. 0.043139423
## Vessel.Weight.Wt.Kg. 0.044568673
## pH.pH.pH. 0.392818670
## Temperature.T.K. 0.319496158
## Generated.heat.Q.kJ. 0.110066552
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.003898025
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.152006994
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.012212893
## Oil.flow.Foil.L.hr. -0.235745559
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.087066818
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.068881185
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.140986160
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.048459624
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.023849756
## Carbon.evolution.rate.CER.g.h. 0.030886802
## Viscosity.Viscosity_offline.centPoise. -0.025725212
## X1.Raman.spec.recorded 0.057315094
## X2.PAT.control.PAT_ref.PAT.ref. 0.057315094
## Batch.reference.Batch_ref.Batch.ref. 0.057315094
## Batch.ID -0.118874559
## Fault.flag -0.116137514
## PC9
## Time..h. -0.022454892
## Aeration.rate.Fg.L.h. -0.049684263
## Sugar.feed.rate.Fs.L.h. 0.397333505
## Acid.flow.rate.Fa.L.h. 0.109975818
## Base.flow.rate.Fb.L.h. -0.318436441
## Heating.cooling.water.flow.rate.Fc.L.h. 0.079393983
## Heating.water.flow.rate.Fh.L.h. -0.195968338
## Water.for.injection.dilution.Fw.L.h. -0.027634043
## Air.head.pressure.pressure.bar. 0.100806285
## Dumped.broth.flow.Fremoved.L.h. -0.067035589
## Substrate.concentration.S.g.L. -0.035382828
## Dissolved.oxygen.concentration.DO2.mg.L. -0.054456829
## Penicillin.concentration.P.g.L. -0.029040294
## Vessel.Volume.V.L. 0.001764422
## Vessel.Weight.Wt.Kg. -0.002049049
## pH.pH.pH. -0.249627906
## Temperature.T.K. 0.258779463
## Generated.heat.Q.kJ. 0.068089750
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.051650360
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.540012788
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.001596532
## Oil.flow.Foil.L.hr. -0.065868571
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.019373827
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.188681803
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.141791423
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.008076985
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.006582625
## Carbon.evolution.rate.CER.g.h. 0.024656572
## Viscosity.Viscosity_offline.centPoise. 0.003235619
## X1.Raman.spec.recorded -0.027634043
## X2.PAT.control.PAT_ref.PAT.ref. -0.027634043
## Batch.reference.Batch_ref.Batch.ref. -0.027634043
## Batch.ID -0.290003811
## Fault.flag -0.291069478
## PC10
## Time..h. 0.007368023
## Aeration.rate.Fg.L.h. 0.078837523
## Sugar.feed.rate.Fs.L.h. -0.353049804
## Acid.flow.rate.Fa.L.h. 0.320297359
## Base.flow.rate.Fb.L.h. 0.352521800
## Heating.cooling.water.flow.rate.Fc.L.h. 0.074682240
## Heating.water.flow.rate.Fh.L.h. 0.078646598
## Water.for.injection.dilution.Fw.L.h. 0.035819733
## Air.head.pressure.pressure.bar. -0.187557538
## Dumped.broth.flow.Fremoved.L.h. -0.236798010
## Substrate.concentration.S.g.L. 0.025889658
## Dissolved.oxygen.concentration.DO2.mg.L. -0.224826585
## Penicillin.concentration.P.g.L. 0.055556607
## Vessel.Volume.V.L. -0.005739401
## Vessel.Weight.Wt.Kg. -0.002262903
## pH.pH.pH. -0.471055664
## Temperature.T.K. 0.009889009
## Generated.heat.Q.kJ. -0.069392040
## carbon.dioxide.percent.in.off.gas.CO2outgas... -0.072981112
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.221537935
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.009895614
## Oil.flow.Foil.L.hr. -0.422204062
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.015372219
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.076919578
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.013336505
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.022221679
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.017415320
## Carbon.evolution.rate.CER.g.h. -0.015750406
## Viscosity.Viscosity_offline.centPoise. -0.008272521
## X1.Raman.spec.recorded 0.035819733
## X2.PAT.control.PAT_ref.PAT.ref. 0.035819733
## Batch.reference.Batch_ref.Batch.ref. 0.035819733
## Batch.ID 0.079845706
## Fault.flag 0.079690239
## PC11
## Time..h. -0.06152017
## Aeration.rate.Fg.L.h. -0.17921669
## Sugar.feed.rate.Fs.L.h. 0.16144713
## Acid.flow.rate.Fa.L.h. -0.02587831
## Base.flow.rate.Fb.L.h. 0.13394244
## Heating.cooling.water.flow.rate.Fc.L.h. -0.04723808
## Heating.water.flow.rate.Fh.L.h. -0.17789397
## Water.for.injection.dilution.Fw.L.h. -0.02711510
## Air.head.pressure.pressure.bar. -0.09452868
## Dumped.broth.flow.Fremoved.L.h. 0.04543940
## Substrate.concentration.S.g.L. -0.04462277
## Dissolved.oxygen.concentration.DO2.mg.L. -0.11007323
## Penicillin.concentration.P.g.L. 0.01558042
## Vessel.Volume.V.L. -0.20876611
## Vessel.Weight.Wt.Kg. -0.17298829
## pH.pH.pH. 0.05484241
## Temperature.T.K. 0.20960731
## Generated.heat.Q.kJ. 0.02018092
## carbon.dioxide.percent.in.off.gas.CO2outgas... -0.05276491
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.41170499
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.01491438
## Oil.flow.Foil.L.hr. 0.25479056
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.16645118
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.13860344
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.07076252
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.10187712
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.04831666
## Carbon.evolution.rate.CER.g.h. -0.05520468
## Viscosity.Viscosity_offline.centPoise. 0.05962940
## X1.Raman.spec.recorded -0.02711510
## X2.PAT.control.PAT_ref.PAT.ref. -0.02711510
## Batch.reference.Batch_ref.Batch.ref. -0.02711510
## Batch.ID 0.46076210
## Fault.flag 0.46413929
## PC12
## Time..h. 0.032018798
## Aeration.rate.Fg.L.h. -0.013148983
## Sugar.feed.rate.Fs.L.h. 0.166350279
## Acid.flow.rate.Fa.L.h. 0.232543850
## Base.flow.rate.Fb.L.h. 0.452277308
## Heating.cooling.water.flow.rate.Fc.L.h. -0.101367422
## Heating.water.flow.rate.Fh.L.h. -0.210731588
## Water.for.injection.dilution.Fw.L.h. 0.014040660
## Air.head.pressure.pressure.bar. 0.196495750
## Dumped.broth.flow.Fremoved.L.h. -0.194465805
## Substrate.concentration.S.g.L. 0.022897068
## Dissolved.oxygen.concentration.DO2.mg.L. 0.489256495
## Penicillin.concentration.P.g.L. -0.004241974
## Vessel.Volume.V.L. 0.093123122
## Vessel.Weight.Wt.Kg. 0.078639443
## pH.pH.pH. -0.231034684
## Temperature.T.K. 0.173769229
## Generated.heat.Q.kJ. 0.093457013
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.058837974
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.226218393
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.025689800
## Oil.flow.Foil.L.hr. 0.179708088
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.297025326
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.070250781
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.011594407
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.167332556
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.057586083
## Carbon.evolution.rate.CER.g.h. 0.036624931
## Viscosity.Viscosity_offline.centPoise. 0.100657196
## X1.Raman.spec.recorded 0.014040660
## X2.PAT.control.PAT_ref.PAT.ref. 0.014040660
## Batch.reference.Batch_ref.Batch.ref. 0.014040660
## Batch.ID -0.069922426
## Fault.flag -0.070409970
## PC13
## Time..h. -0.094320360
## Aeration.rate.Fg.L.h. 0.153493269
## Sugar.feed.rate.Fs.L.h. 0.058303833
## Acid.flow.rate.Fa.L.h. -0.044994814
## Base.flow.rate.Fb.L.h. -0.028205404
## Heating.cooling.water.flow.rate.Fc.L.h. 0.402237690
## Heating.water.flow.rate.Fh.L.h. 0.357423112
## Water.for.injection.dilution.Fw.L.h. -0.106466855
## Air.head.pressure.pressure.bar. 0.249617808
## Dumped.broth.flow.Fremoved.L.h. 0.019872408
## Substrate.concentration.S.g.L. -0.144549835
## Dissolved.oxygen.concentration.DO2.mg.L. 0.215523392
## Penicillin.concentration.P.g.L. -0.083719700
## Vessel.Volume.V.L. -0.172097383
## Vessel.Weight.Wt.Kg. -0.149748475
## pH.pH.pH. 0.048129297
## Temperature.T.K. -0.340572293
## Generated.heat.Q.kJ. 0.008313938
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.080257096
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.141562848
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.043271925
## Oil.flow.Foil.L.hr. -0.224641530
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.391039065
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.089686563
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.053589581
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.220961773
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.082217074
## Carbon.evolution.rate.CER.g.h. 0.027406660
## Viscosity.Viscosity_offline.centPoise. 0.120886657
## X1.Raman.spec.recorded -0.106466855
## X2.PAT.control.PAT_ref.PAT.ref. -0.106466855
## Batch.reference.Batch_ref.Batch.ref. -0.106466855
## Batch.ID 0.053829736
## Fault.flag 0.049709984
## PC14
## Time..h. -0.066331211
## Aeration.rate.Fg.L.h. 0.001282018
## Sugar.feed.rate.Fs.L.h. 0.136929824
## Acid.flow.rate.Fa.L.h. 0.084626677
## Base.flow.rate.Fb.L.h. 0.115263954
## Heating.cooling.water.flow.rate.Fc.L.h. 0.152867246
## Heating.water.flow.rate.Fh.L.h. 0.081296062
## Water.for.injection.dilution.Fw.L.h. -0.065939900
## Air.head.pressure.pressure.bar. 0.258950282
## Dumped.broth.flow.Fremoved.L.h. -0.089066067
## Substrate.concentration.S.g.L. -0.101656089
## Dissolved.oxygen.concentration.DO2.mg.L. 0.339636486
## Penicillin.concentration.P.g.L. -0.037987199
## Vessel.Volume.V.L. -0.145619131
## Vessel.Weight.Wt.Kg. -0.123332109
## pH.pH.pH. -0.142204727
## Temperature.T.K. -0.080386850
## Generated.heat.Q.kJ. 0.077260832
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.082017005
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.055716273
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.064464415
## Oil.flow.Foil.L.hr. 0.061523551
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.630649655
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.001820586
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.007899085
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.349969319
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.125173039
## Carbon.evolution.rate.CER.g.h. 0.028734431
## Viscosity.Viscosity_offline.centPoise. -0.202042297
## X1.Raman.spec.recorded -0.065939900
## X2.PAT.control.PAT_ref.PAT.ref. -0.065939900
## Batch.reference.Batch_ref.Batch.ref. -0.065939900
## Batch.ID 0.146012301
## Fault.flag 0.145515154
## PC15
## Time..h. 0.063365079
## Aeration.rate.Fg.L.h. -0.137547519
## Sugar.feed.rate.Fs.L.h. -0.189339469
## Acid.flow.rate.Fa.L.h. 0.071926728
## Base.flow.rate.Fb.L.h. -0.018916448
## Heating.cooling.water.flow.rate.Fc.L.h. 0.238351618
## Heating.water.flow.rate.Fh.L.h. 0.162766215
## Water.for.injection.dilution.Fw.L.h. -0.036180928
## Air.head.pressure.pressure.bar. -0.146866992
## Dumped.broth.flow.Fremoved.L.h. 0.053153648
## Substrate.concentration.S.g.L. 0.070782629
## Dissolved.oxygen.concentration.DO2.mg.L. 0.244682949
## Penicillin.concentration.P.g.L. -0.189671835
## Vessel.Volume.V.L. 0.517303247
## Vessel.Weight.Wt.Kg. 0.399551199
## pH.pH.pH. 0.041207076
## Temperature.T.K. -0.101026775
## Generated.heat.Q.kJ. -0.090488498
## carbon.dioxide.percent.in.off.gas.CO2outgas... -0.124995338
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.314243154
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.002976423
## Oil.flow.Foil.L.hr. 0.319453839
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.001789519
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.107014303
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.146381374
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.036405703
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.004467669
## Carbon.evolution.rate.CER.g.h. -0.110165036
## Viscosity.Viscosity_offline.centPoise. 0.014714814
## X1.Raman.spec.recorded -0.036180928
## X2.PAT.control.PAT_ref.PAT.ref. -0.036180928
## Batch.reference.Batch_ref.Batch.ref. -0.036180928
## Batch.ID 0.073426950
## Fault.flag 0.078438490
## PC16
## Time..h. 0.0184051792
## Aeration.rate.Fg.L.h. 0.1146565675
## Sugar.feed.rate.Fs.L.h. 0.0978933880
## Acid.flow.rate.Fa.L.h. 0.0806119141
## Base.flow.rate.Fb.L.h. 0.0865316507
## Heating.cooling.water.flow.rate.Fc.L.h. 0.2572843203
## Heating.water.flow.rate.Fh.L.h. 0.1950785042
## Water.for.injection.dilution.Fw.L.h. 0.0401843666
## Air.head.pressure.pressure.bar. -0.0811645556
## Dumped.broth.flow.Fremoved.L.h. -0.1280154456
## Substrate.concentration.S.g.L. 0.0323404135
## Dissolved.oxygen.concentration.DO2.mg.L. -0.2829501577
## Penicillin.concentration.P.g.L. 0.0645180010
## Vessel.Volume.V.L. -0.0361698448
## Vessel.Weight.Wt.Kg. -0.0213198098
## pH.pH.pH. -0.1585321547
## Temperature.T.K. -0.1511903401
## Generated.heat.Q.kJ. 0.0220838850
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.0050521496
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.0753118399
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.0007399452
## Oil.flow.Foil.L.hr. 0.4910684103
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.0141044198
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.3388721722
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.4969766721
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.0014268662
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.0127687718
## Carbon.evolution.rate.CER.g.h. 0.0315662125
## Viscosity.Viscosity_offline.centPoise. -0.0132505434
## X1.Raman.spec.recorded 0.0401843666
## X2.PAT.control.PAT_ref.PAT.ref. 0.0401843666
## Batch.reference.Batch_ref.Batch.ref. 0.0401843666
## Batch.ID -0.2111153193
## Fault.flag -0.1974276544
## PC17
## Time..h. -0.0009414251
## Aeration.rate.Fg.L.h. 0.5798467052
## Sugar.feed.rate.Fs.L.h. -0.4800408919
## Acid.flow.rate.Fa.L.h. -0.0462901930
## Base.flow.rate.Fb.L.h. -0.0592740971
## Heating.cooling.water.flow.rate.Fc.L.h. -0.2092463886
## Heating.water.flow.rate.Fh.L.h. -0.1127037877
## Water.for.injection.dilution.Fw.L.h. 0.0248346686
## Air.head.pressure.pressure.bar. 0.1571253689
## Dumped.broth.flow.Fremoved.L.h. 0.0133341035
## Substrate.concentration.S.g.L. -0.0230510442
## Dissolved.oxygen.concentration.DO2.mg.L. 0.1274992656
## Penicillin.concentration.P.g.L. 0.0798749534
## Vessel.Volume.V.L. -0.1671522727
## Vessel.Weight.Wt.Kg. -0.1246311565
## pH.pH.pH. 0.0265994584
## Temperature.T.K. 0.0624276978
## Generated.heat.Q.kJ. 0.0004925214
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.0012538999
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.2412093261
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.0087788538
## Oil.flow.Foil.L.hr. 0.3698733541
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.0119654475
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.2592379660
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.0381224364
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.0159359791
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.0160878906
## Carbon.evolution.rate.CER.g.h. 0.0675714241
## Viscosity.Viscosity_offline.centPoise. -0.0049331471
## X1.Raman.spec.recorded 0.0248346686
## X2.PAT.control.PAT_ref.PAT.ref. 0.0248346686
## Batch.reference.Batch_ref.Batch.ref. 0.0248346686
## Batch.ID -0.0422045393
## Fault.flag -0.0431843816
## PC18
## Time..h. -0.0769262121
## Aeration.rate.Fg.L.h. 0.4424318850
## Sugar.feed.rate.Fs.L.h. 0.2306228054
## Acid.flow.rate.Fa.L.h. 0.0333831982
## Base.flow.rate.Fb.L.h. 0.0001203153
## Heating.cooling.water.flow.rate.Fc.L.h. -0.1637239939
## Heating.water.flow.rate.Fh.L.h. -0.1186965925
## Water.for.injection.dilution.Fw.L.h. -0.1891721574
## Air.head.pressure.pressure.bar. 0.0375830649
## Dumped.broth.flow.Fremoved.L.h. -0.0030281198
## Substrate.concentration.S.g.L. -0.1235240546
## Dissolved.oxygen.concentration.DO2.mg.L. -0.1633385131
## Penicillin.concentration.P.g.L. -0.3076843654
## Vessel.Volume.V.L. 0.2842796189
## Vessel.Weight.Wt.Kg. 0.1950569331
## pH.pH.pH. -0.0096197758
## Temperature.T.K. 0.1062893814
## Generated.heat.Q.kJ. -0.0252343567
## carbon.dioxide.percent.in.off.gas.CO2outgas... -0.1046938392
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.1084310417
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.0170732109
## Oil.flow.Foil.L.hr. -0.1386169936
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.0255123424
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.1561640049
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.4293636849
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.0220125748
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.0273899491
## Carbon.evolution.rate.CER.g.h. -0.0855927077
## Viscosity.Viscosity_offline.centPoise. 0.0067024606
## X1.Raman.spec.recorded -0.1891721574
## X2.PAT.control.PAT_ref.PAT.ref. -0.1891721574
## Batch.reference.Batch_ref.Batch.ref. -0.1891721574
## Batch.ID 0.1358061205
## Fault.flag 0.1114170518
## PC19
## Time..h. -0.064061981
## Aeration.rate.Fg.L.h. -0.335177188
## Sugar.feed.rate.Fs.L.h. -0.396774499
## Acid.flow.rate.Fa.L.h. 0.018041617
## Base.flow.rate.Fb.L.h. 0.013892162
## Heating.cooling.water.flow.rate.Fc.L.h. -0.076787044
## Heating.water.flow.rate.Fh.L.h. -0.085815869
## Water.for.injection.dilution.Fw.L.h. -0.127504826
## Air.head.pressure.pressure.bar. 0.414314092
## Dumped.broth.flow.Fremoved.L.h. 0.029158323
## Substrate.concentration.S.g.L. -0.160414292
## Dissolved.oxygen.concentration.DO2.mg.L. -0.280648806
## Penicillin.concentration.P.g.L. -0.126454396
## Vessel.Volume.V.L. 0.140256536
## Vessel.Weight.Wt.Kg. 0.106128889
## pH.pH.pH. -0.010977858
## Temperature.T.K. 0.030555712
## Generated.heat.Q.kJ. 0.219256045
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.453960480
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.045464978
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.020030104
## Oil.flow.Foil.L.hr. 0.028252851
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.032605591
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.117608033
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.078463196
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.027917646
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.056002735
## Carbon.evolution.rate.CER.g.h. 0.196229450
## Viscosity.Viscosity_offline.centPoise. 0.023571540
## X1.Raman.spec.recorded -0.127504826
## X2.PAT.control.PAT_ref.PAT.ref. -0.127504826
## Batch.reference.Batch_ref.Batch.ref. -0.127504826
## Batch.ID -0.002469697
## Fault.flag -0.029594081
## PC20
## Time..h. -0.058065110
## Aeration.rate.Fg.L.h. 0.001532730
## Sugar.feed.rate.Fs.L.h. -0.033877547
## Acid.flow.rate.Fa.L.h. 0.008689025
## Base.flow.rate.Fb.L.h. 0.004211067
## Heating.cooling.water.flow.rate.Fc.L.h. 0.005777409
## Heating.water.flow.rate.Fh.L.h. 0.003254063
## Water.for.injection.dilution.Fw.L.h. -0.016299917
## Air.head.pressure.pressure.bar. -0.038483814
## Dumped.broth.flow.Fremoved.L.h. 0.006655604
## Substrate.concentration.S.g.L. -0.044893258
## Dissolved.oxygen.concentration.DO2.mg.L. 0.004042720
## Penicillin.concentration.P.g.L. 0.052017022
## Vessel.Volume.V.L. 0.028371664
## Vessel.Weight.Wt.Kg. 0.022961486
## pH.pH.pH. -0.010729526
## Temperature.T.K. 0.023051873
## Generated.heat.Q.kJ. -0.088397475
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.116191137
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.012446484
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.328259255
## Oil.flow.Foil.L.hr. -0.001346367
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.049614265
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.024032327
## Oxygen.in.percent.in.off.gas.O2.O2...... -0.024644259
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.466348552
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.790877509
## Carbon.evolution.rate.CER.g.h. 0.085525674
## Viscosity.Viscosity_offline.centPoise. -0.049217644
## X1.Raman.spec.recorded -0.016299917
## X2.PAT.control.PAT_ref.PAT.ref. -0.016299917
## Batch.reference.Batch_ref.Batch.ref. -0.016299917
## Batch.ID 0.019117420
## Fault.flag 0.009716809
## PC21
## Time..h. -1.121703e-01
## Aeration.rate.Fg.L.h. -1.758874e-01
## Sugar.feed.rate.Fs.L.h. -2.069655e-03
## Acid.flow.rate.Fa.L.h. -8.447166e-05
## Base.flow.rate.Fb.L.h. -9.115224e-05
## Heating.cooling.water.flow.rate.Fc.L.h. 1.114930e-02
## Heating.water.flow.rate.Fh.L.h. 1.773871e-03
## Water.for.injection.dilution.Fw.L.h. 3.221559e-02
## Air.head.pressure.pressure.bar. -2.867438e-02
## Dumped.broth.flow.Fremoved.L.h. 2.522958e-02
## Substrate.concentration.S.g.L. -8.089627e-02
## Dissolved.oxygen.concentration.DO2.mg.L. 5.834586e-02
## Penicillin.concentration.P.g.L. 1.919260e-01
## Vessel.Volume.V.L. 5.478297e-02
## Vessel.Weight.Wt.Kg. 3.849328e-02
## pH.pH.pH. 4.278644e-03
## Temperature.T.K. 1.850084e-02
## Generated.heat.Q.kJ. -6.754617e-02
## carbon.dioxide.percent.in.off.gas.CO2outgas... 1.768496e-02
## PAA.flow.Fpaa.PAA.flow..L.h.. -2.425657e-02
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -2.804814e-01
## Oil.flow.Foil.L.hr. 1.741453e-02
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 1.542981e-01
## Oxygen.Uptake.Rate.OUR..g.min...1... 3.165397e-01
## Oxygen.in.percent.in.off.gas.O2.O2...... 2.506273e-01
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 4.751024e-01
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 2.389011e-01
## Carbon.evolution.rate.CER.g.h. 8.092608e-02
## Viscosity.Viscosity_offline.centPoise. -5.808609e-01
## X1.Raman.spec.recorded 3.221559e-02
## X2.PAT.control.PAT_ref.PAT.ref. 3.221559e-02
## Batch.reference.Batch_ref.Batch.ref. 3.221559e-02
## Batch.ID -8.836214e-03
## Fault.flag 3.214699e-02
## PC22
## Time..h. -0.2133954733
## Aeration.rate.Fg.L.h. -0.2285876932
## Sugar.feed.rate.Fs.L.h. 0.0056679460
## Acid.flow.rate.Fa.L.h. -0.0059378756
## Base.flow.rate.Fb.L.h. -0.0002423424
## Heating.cooling.water.flow.rate.Fc.L.h. 0.0098614459
## Heating.water.flow.rate.Fh.L.h. 0.0069077212
## Water.for.injection.dilution.Fw.L.h. 0.0490201024
## Air.head.pressure.pressure.bar. -0.1585252142
## Dumped.broth.flow.Fremoved.L.h. 0.0391450339
## Substrate.concentration.S.g.L. -0.1551100249
## Dissolved.oxygen.concentration.DO2.mg.L. 0.1165830831
## Penicillin.concentration.P.g.L. 0.3616488642
## Vessel.Volume.V.L. 0.0337915493
## Vessel.Weight.Wt.Kg. 0.0215969732
## pH.pH.pH. 0.0031926911
## Temperature.T.K. 0.0115981179
## Generated.heat.Q.kJ. -0.0654634493
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.0943491538
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.0381357137
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.1468840956
## Oil.flow.Foil.L.hr. 0.0312430999
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.1015997370
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.4845546136
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.3729060397
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.3197153345
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.0870976421
## Carbon.evolution.rate.CER.g.h. 0.1881576951
## Viscosity.Viscosity_offline.centPoise. 0.3586798287
## X1.Raman.spec.recorded 0.0490201024
## X2.PAT.control.PAT_ref.PAT.ref. 0.0490201024
## Batch.reference.Batch_ref.Batch.ref. 0.0490201024
## Batch.ID 0.0032561035
## Fault.flag 0.0171251856
## PC23
## Time..h. 0.208243312
## Aeration.rate.Fg.L.h. -0.250152247
## Sugar.feed.rate.Fs.L.h. -0.092749004
## Acid.flow.rate.Fa.L.h. -0.011063729
## Base.flow.rate.Fb.L.h. 0.013004355
## Heating.cooling.water.flow.rate.Fc.L.h. -0.032383617
## Heating.water.flow.rate.Fh.L.h. -0.018774474
## Water.for.injection.dilution.Fw.L.h. 0.066427881
## Air.head.pressure.pressure.bar. 0.265682697
## Dumped.broth.flow.Fremoved.L.h. -0.028746209
## Substrate.concentration.S.g.L. 0.177299283
## Dissolved.oxygen.concentration.DO2.mg.L. -0.070208832
## Penicillin.concentration.P.g.L. -0.158479420
## Vessel.Volume.V.L. -0.098038119
## Vessel.Weight.Wt.Kg. -0.077444682
## pH.pH.pH. -0.006685680
## Temperature.T.K. -0.123467194
## Generated.heat.Q.kJ. 0.494759391
## carbon.dioxide.percent.in.off.gas.CO2outgas... -0.408438594
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.008978641
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.077521453
## Oil.flow.Foil.L.hr. 0.009542347
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.012033325
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.314550212
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.215844211
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.064955109
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.160987493
## Carbon.evolution.rate.CER.g.h. -0.325977733
## Viscosity.Viscosity_offline.centPoise. 0.029967834
## X1.Raman.spec.recorded 0.066427881
## X2.PAT.control.PAT_ref.PAT.ref. 0.066427881
## Batch.reference.Batch_ref.Batch.ref. 0.066427881
## Batch.ID -0.039373269
## Fault.flag 0.003109683
## PC24
## Time..h. 0.059939764
## Aeration.rate.Fg.L.h. -0.119488605
## Sugar.feed.rate.Fs.L.h. -0.012533450
## Acid.flow.rate.Fa.L.h. -0.001594851
## Base.flow.rate.Fb.L.h. -0.006441692
## Heating.cooling.water.flow.rate.Fc.L.h. 0.036318771
## Heating.water.flow.rate.Fh.L.h. 0.041747411
## Water.for.injection.dilution.Fw.L.h. 0.077452183
## Air.head.pressure.pressure.bar. 0.584983441
## Dumped.broth.flow.Fremoved.L.h. -0.008751749
## Substrate.concentration.S.g.L. 0.105249651
## Dissolved.oxygen.concentration.DO2.mg.L. -0.113185519
## Penicillin.concentration.P.g.L. 0.039507229
## Vessel.Volume.V.L. 0.013691104
## Vessel.Weight.Wt.Kg. 0.014062644
## pH.pH.pH. -0.003061390
## Temperature.T.K. 0.150373359
## Generated.heat.Q.kJ. -0.706223207
## carbon.dioxide.percent.in.off.gas.CO2outgas... -0.196553049
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.005765153
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.022294453
## Oil.flow.Foil.L.hr. 0.000734295
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -0.013486538
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.004411432
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.087417459
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.040218901
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -0.018044371
## Carbon.evolution.rate.CER.g.h. -0.101766751
## Viscosity.Viscosity_offline.centPoise. 0.048338691
## X1.Raman.spec.recorded 0.077452183
## X2.PAT.control.PAT_ref.PAT.ref. 0.077452183
## Batch.reference.Batch_ref.Batch.ref. 0.077452183
## Batch.ID 0.058001656
## Fault.flag -0.019348019
## PC25
## Time..h. 0.436409041
## Aeration.rate.Fg.L.h. -0.078803225
## Sugar.feed.rate.Fs.L.h. -0.002364755
## Acid.flow.rate.Fa.L.h. -0.002494114
## Base.flow.rate.Fb.L.h. -0.005551966
## Heating.cooling.water.flow.rate.Fc.L.h. 0.006544252
## Heating.water.flow.rate.Fh.L.h. 0.007183061
## Water.for.injection.dilution.Fw.L.h. 0.009751467
## Air.head.pressure.pressure.bar. -0.215480958
## Dumped.broth.flow.Fremoved.L.h. -0.015972526
## Substrate.concentration.S.g.L. 0.337523230
## Dissolved.oxygen.concentration.DO2.mg.L. 0.093139358
## Penicillin.concentration.P.g.L. -0.475968707
## Vessel.Volume.V.L. -0.206178884
## Vessel.Weight.Wt.Kg. -0.119432655
## pH.pH.pH. -0.006491864
## Temperature.T.K. 0.057716613
## Generated.heat.Q.kJ. -0.224537504
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.437484672
## PAA.flow.Fpaa.PAA.flow..L.h.. -0.009759106
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.001137262
## Oil.flow.Foil.L.hr. 0.011354706
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.004196004
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.231717622
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.196556763
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -0.004296299
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.002711113
## Carbon.evolution.rate.CER.g.h. 0.101822172
## Viscosity.Viscosity_offline.centPoise. -0.001402599
## X1.Raman.spec.recorded 0.009751467
## X2.PAT.control.PAT_ref.PAT.ref. 0.009751467
## Batch.reference.Batch_ref.Batch.ref. 0.009751467
## Batch.ID -0.022846691
## Fault.flag 0.039295921
## PC26
## Time..h. 0.0163475520
## Aeration.rate.Fg.L.h. -0.0135959358
## Sugar.feed.rate.Fs.L.h. 0.0019256005
## Acid.flow.rate.Fa.L.h. -0.0018061256
## Base.flow.rate.Fb.L.h. 0.0024028478
## Heating.cooling.water.flow.rate.Fc.L.h. 0.0051744514
## Heating.water.flow.rate.Fh.L.h. 0.0023962589
## Water.for.injection.dilution.Fw.L.h. 0.0061026013
## Air.head.pressure.pressure.bar. -0.0466665552
## Dumped.broth.flow.Fremoved.L.h. -0.0015968624
## Substrate.concentration.S.g.L. 0.0212934496
## Dissolved.oxygen.concentration.DO2.mg.L. 0.0160340889
## Penicillin.concentration.P.g.L. -0.0130292716
## Vessel.Volume.V.L. -0.0166311821
## Vessel.Weight.Wt.Kg. -0.0118725001
## pH.pH.pH. -0.0001319993
## Temperature.T.K. -0.0110039234
## Generated.heat.Q.kJ. 0.0384582203
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.0089521956
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.0015448749
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -0.0076227945
## Oil.flow.Foil.L.hr. 0.0099876928
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 0.0048210714
## Oxygen.Uptake.Rate.OUR..g.min...1... 0.0298617221
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.0170079209
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.0118587347
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.0067320848
## Carbon.evolution.rate.CER.g.h. 0.0050325625
## Viscosity.Viscosity_offline.centPoise. -0.0157794000
## X1.Raman.spec.recorded 0.0061026013
## X2.PAT.control.PAT_ref.PAT.ref. 0.0061026013
## Batch.reference.Batch_ref.Batch.ref. 0.0061026013
## Batch.ID 0.7009285919
## Fault.flag -0.7078627166
## PC27
## Time..h. 3.824358e-01
## Aeration.rate.Fg.L.h. -2.144494e-02
## Sugar.feed.rate.Fs.L.h. 8.181761e-03
## Acid.flow.rate.Fa.L.h. 3.850820e-04
## Base.flow.rate.Fb.L.h. -2.032307e-03
## Heating.cooling.water.flow.rate.Fc.L.h. -4.750016e-04
## Heating.water.flow.rate.Fh.L.h. 4.749223e-05
## Water.for.injection.dilution.Fw.L.h. 1.761230e-01
## Air.head.pressure.pressure.bar. -3.459291e-02
## Dumped.broth.flow.Fremoved.L.h. -5.273818e-04
## Substrate.concentration.S.g.L. -7.816838e-01
## Dissolved.oxygen.concentration.DO2.mg.L. 5.685468e-04
## Penicillin.concentration.P.g.L. -2.588258e-01
## Vessel.Volume.V.L. 2.466527e-02
## Vessel.Weight.Wt.Kg. -3.034104e-02
## pH.pH.pH. -1.735305e-04
## Temperature.T.K. 8.629823e-03
## Generated.heat.Q.kJ. -3.206117e-02
## carbon.dioxide.percent.in.off.gas.CO2outgas... -1.344806e-01
## PAA.flow.Fpaa.PAA.flow..L.h.. -3.283869e-03
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 3.728299e-03
## Oil.flow.Foil.L.hr. 4.956661e-03
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -1.403133e-03
## Oxygen.Uptake.Rate.OUR..g.min...1... -2.111932e-02
## Oxygen.in.percent.in.off.gas.O2.O2...... -9.939939e-03
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 3.047424e-03
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -7.493784e-03
## Carbon.evolution.rate.CER.g.h. 1.688498e-01
## Viscosity.Viscosity_offline.centPoise. 2.164928e-03
## X1.Raman.spec.recorded 1.761230e-01
## X2.PAT.control.PAT_ref.PAT.ref. 1.761230e-01
## Batch.reference.Batch_ref.Batch.ref. 1.761230e-01
## Batch.ID 4.883384e-03
## Fault.flag 7.663584e-05
## PC28
## Time..h. 2.691022e-01
## Aeration.rate.Fg.L.h. 5.700884e-02
## Sugar.feed.rate.Fs.L.h. 9.354123e-03
## Acid.flow.rate.Fa.L.h. -4.440018e-05
## Base.flow.rate.Fb.L.h. -1.691743e-04
## Heating.cooling.water.flow.rate.Fc.L.h. 6.437068e-04
## Heating.water.flow.rate.Fh.L.h. 8.952013e-04
## Water.for.injection.dilution.Fw.L.h. -2.189527e-02
## Air.head.pressure.pressure.bar. -2.008607e-02
## Dumped.broth.flow.Fremoved.L.h. -1.008390e-03
## Substrate.concentration.S.g.L. -2.330149e-01
## Dissolved.oxygen.concentration.DO2.mg.L. 8.219678e-03
## Penicillin.concentration.P.g.L. 3.210617e-01
## Vessel.Volume.V.L. 1.855518e-02
## Vessel.Weight.Wt.Kg. 4.831416e-02
## pH.pH.pH. -1.037851e-03
## Temperature.T.K. 8.279291e-03
## Generated.heat.Q.kJ. -3.313066e-02
## carbon.dioxide.percent.in.off.gas.CO2outgas... 4.231488e-01
## PAA.flow.Fpaa.PAA.flow..L.h.. 2.777682e-03
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -5.412042e-04
## Oil.flow.Foil.L.hr. -1.062298e-03
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 4.383784e-04
## Oxygen.Uptake.Rate.OUR..g.min...1... 2.013715e-02
## Oxygen.in.percent.in.off.gas.O2.O2...... 2.074701e-02
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -1.411651e-03
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 6.170625e-04
## Carbon.evolution.rate.CER.g.h. -7.620279e-01
## Viscosity.Viscosity_offline.centPoise. 8.691441e-04
## X1.Raman.spec.recorded -2.189527e-02
## X2.PAT.control.PAT_ref.PAT.ref. -2.189527e-02
## Batch.reference.Batch_ref.Batch.ref. -2.189527e-02
## Batch.ID 3.213801e-03
## Fault.flag -5.756874e-03
## PC29
## Time..h. 6.120532e-01
## Aeration.rate.Fg.L.h. -4.064618e-02
## Sugar.feed.rate.Fs.L.h. 1.577747e-03
## Acid.flow.rate.Fa.L.h. -1.214094e-04
## Base.flow.rate.Fb.L.h. 2.776379e-04
## Heating.cooling.water.flow.rate.Fc.L.h. 1.301870e-03
## Heating.water.flow.rate.Fh.L.h. 9.975399e-04
## Water.for.injection.dilution.Fw.L.h. -2.672830e-01
## Air.head.pressure.pressure.bar. -1.025727e-03
## Dumped.broth.flow.Fremoved.L.h. 2.712013e-04
## Substrate.concentration.S.g.L. 1.754361e-02
## Dissolved.oxygen.concentration.DO2.mg.L. 1.680678e-04
## Penicillin.concentration.P.g.L. 4.152638e-01
## Vessel.Volume.V.L. -1.035103e-01
## Vessel.Weight.Wt.Kg. 1.246625e-01
## pH.pH.pH. 1.473822e-04
## Temperature.T.K. 1.527968e-03
## Generated.heat.Q.kJ. -8.467692e-03
## carbon.dioxide.percent.in.off.gas.CO2outgas... -2.374002e-01
## PAA.flow.Fpaa.PAA.flow..L.h.. -5.663866e-05
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -1.800678e-03
## Oil.flow.Foil.L.hr. -1.538917e-03
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 1.018162e-03
## Oxygen.Uptake.Rate.OUR..g.min...1... -5.683822e-03
## Oxygen.in.percent.in.off.gas.O2.O2...... -3.969260e-03
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 9.530681e-04
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 5.998780e-04
## Carbon.evolution.rate.CER.g.h. 2.871709e-01
## Viscosity.Viscosity_offline.centPoise. -8.413957e-04
## X1.Raman.spec.recorded -2.672830e-01
## X2.PAT.control.PAT_ref.PAT.ref. -2.672830e-01
## Batch.reference.Batch_ref.Batch.ref. -2.672830e-01
## Batch.ID -9.883312e-05
## Fault.flag -2.819672e-03
## PC30
## Time..h. 1.230256e-01
## Aeration.rate.Fg.L.h. 7.877497e-04
## Sugar.feed.rate.Fs.L.h. -6.628802e-05
## Acid.flow.rate.Fa.L.h. -2.229730e-06
## Base.flow.rate.Fb.L.h. 1.545568e-05
## Heating.cooling.water.flow.rate.Fc.L.h. 3.186020e-05
## Heating.water.flow.rate.Fh.L.h. 2.080165e-05
## Water.for.injection.dilution.Fw.L.h. -3.410205e-02
## Air.head.pressure.pressure.bar. 5.688225e-04
## Dumped.broth.flow.Fremoved.L.h. 6.714456e-05
## Substrate.concentration.S.g.L. 5.618848e-02
## Dissolved.oxygen.concentration.DO2.mg.L. -2.800477e-04
## Penicillin.concentration.P.g.L. 8.938592e-02
## Vessel.Volume.V.L. 6.068336e-01
## Vessel.Weight.Wt.Kg. -7.741786e-01
## pH.pH.pH. -2.906766e-05
## Temperature.T.K. 2.697188e-05
## Generated.heat.Q.kJ. -1.591079e-04
## carbon.dioxide.percent.in.off.gas.CO2outgas... 2.143558e-03
## PAA.flow.Fpaa.PAA.flow..L.h.. -7.864233e-05
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -1.201987e-02
## Oil.flow.Foil.L.hr. -8.170999e-05
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 4.732881e-03
## Oxygen.Uptake.Rate.OUR..g.min...1... -1.054041e-03
## Oxygen.in.percent.in.off.gas.O2.O2...... -1.002596e-03
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 2.992592e-03
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -3.543366e-03
## Carbon.evolution.rate.CER.g.h. 3.472656e-02
## Viscosity.Viscosity_offline.centPoise. 8.008736e-03
## X1.Raman.spec.recorded -3.410205e-02
## X2.PAT.control.PAT_ref.PAT.ref. -3.410205e-02
## Batch.reference.Batch_ref.Batch.ref. -3.410205e-02
## Batch.ID -3.689382e-04
## Fault.flag 2.077603e-04
## PC31
## Time..h. 2.934142e-03
## Aeration.rate.Fg.L.h. -6.526325e-06
## Sugar.feed.rate.Fs.L.h. 9.905780e-06
## Acid.flow.rate.Fa.L.h. -5.206202e-07
## Base.flow.rate.Fb.L.h. -7.790127e-07
## Heating.cooling.water.flow.rate.Fc.L.h. 4.514214e-06
## Heating.water.flow.rate.Fh.L.h. 9.917268e-06
## Water.for.injection.dilution.Fw.L.h. -8.834319e-04
## Air.head.pressure.pressure.bar. 3.081947e-05
## Dumped.broth.flow.Fremoved.L.h. -1.386713e-06
## Substrate.concentration.S.g.L. 7.550015e-04
## Dissolved.oxygen.concentration.DO2.mg.L. -4.634964e-06
## Penicillin.concentration.P.g.L. 2.122122e-03
## Vessel.Volume.V.L. 9.518125e-03
## Vessel.Weight.Wt.Kg. -1.211968e-02
## pH.pH.pH. -1.713164e-06
## Temperature.T.K. 1.722041e-05
## Generated.heat.Q.kJ. -9.863655e-05
## carbon.dioxide.percent.in.off.gas.CO2outgas... -4.164241e-05
## PAA.flow.Fpaa.PAA.flow..L.h.. -7.435965e-07
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 7.576183e-01
## Oil.flow.Foil.L.hr. -3.697291e-06
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -2.979014e-01
## Oxygen.Uptake.Rate.OUR..g.min...1... -1.630360e-05
## Oxygen.in.percent.in.off.gas.O2.O2...... -6.535956e-06
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -1.838119e-01
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 2.188254e-01
## Carbon.evolution.rate.CER.g.h. 4.753065e-04
## Viscosity.Viscosity_offline.centPoise. -5.053152e-01
## X1.Raman.spec.recorded -8.834319e-04
## X2.PAT.control.PAT_ref.PAT.ref. -8.834319e-04
## Batch.reference.Batch_ref.Batch.ref. -8.834319e-04
## Batch.ID -3.937741e-05
## Fault.flag 3.452151e-05
## PC32
## Time..h. 0.000000e+00
## Aeration.rate.Fg.L.h. 1.480418e-15
## Sugar.feed.rate.Fs.L.h. 5.098693e-16
## Acid.flow.rate.Fa.L.h. -8.470456e-17
## Base.flow.rate.Fb.L.h. 5.021402e-17
## Heating.cooling.water.flow.rate.Fc.L.h. -3.628449e-17
## Heating.water.flow.rate.Fh.L.h. 3.404993e-17
## Water.for.injection.dilution.Fw.L.h. -8.660246e-01
## Air.head.pressure.pressure.bar. -2.234824e-16
## Dumped.broth.flow.Fremoved.L.h. 1.297160e-16
## Substrate.concentration.S.g.L. 1.116717e-14
## Dissolved.oxygen.concentration.DO2.mg.L. -1.978694e-16
## Penicillin.concentration.P.g.L. 9.307275e-15
## Vessel.Volume.V.L. 7.648210e-14
## Vessel.Weight.Wt.Kg. -9.579875e-14
## pH.pH.pH. -5.640648e-19
## Temperature.T.K. -3.022664e-16
## Generated.heat.Q.kJ. 1.023344e-15
## carbon.dioxide.percent.in.off.gas.CO2outgas... 3.510676e-15
## PAA.flow.Fpaa.PAA.flow..L.h.. -5.346994e-17
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -3.308645e-12
## Oil.flow.Foil.L.hr. 2.533045e-17
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 1.300895e-12
## Oxygen.Uptake.Rate.OUR..g.min...1... -2.911353e-16
## Oxygen.in.percent.in.off.gas.O2.O2...... -1.272273e-16
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 8.027419e-13
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -9.555012e-13
## Carbon.evolution.rate.CER.g.h. -1.264149e-15
## Viscosity.Viscosity_offline.centPoise. 2.206775e-12
## X1.Raman.spec.recorded 2.897609e-01
## X2.PAT.control.PAT_ref.PAT.ref. 2.881678e-01
## Batch.reference.Batch_ref.Batch.ref. 2.880959e-01
## Batch.ID 8.419644e-17
## Fault.flag -2.479307e-16
## PC33
## Time..h. 0.000000e+00
## Aeration.rate.Fg.L.h. 3.333268e-17
## Sugar.feed.rate.Fs.L.h. 9.242865e-18
## Acid.flow.rate.Fa.L.h. -9.434576e-18
## Base.flow.rate.Fb.L.h. -1.068384e-17
## Heating.cooling.water.flow.rate.Fc.L.h. 7.001312e-19
## Heating.water.flow.rate.Fh.L.h. 2.576885e-18
## Water.for.injection.dilution.Fw.L.h. 1.149576e-03
## Air.head.pressure.pressure.bar. -1.956364e-17
## Dumped.broth.flow.Fremoved.L.h. -1.987380e-18
## Substrate.concentration.S.g.L. 6.955059e-18
## Dissolved.oxygen.concentration.DO2.mg.L. 2.859822e-18
## Penicillin.concentration.P.g.L. -8.756175e-18
## Vessel.Volume.V.L. -2.147666e-16
## Vessel.Weight.Wt.Kg. 2.638422e-16
## pH.pH.pH. -4.775257e-18
## Temperature.T.K. 6.336641e-18
## Generated.heat.Q.kJ. 3.020115e-17
## carbon.dioxide.percent.in.off.gas.CO2outgas... -1.570369e-17
## PAA.flow.Fpaa.PAA.flow..L.h.. 1.393522e-17
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... -2.668129e-17
## Oil.flow.Foil.L.hr. 6.089183e-19
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... 1.555737e-17
## Oxygen.Uptake.Rate.OUR..g.min...1... -1.163227e-17
## Oxygen.in.percent.in.off.gas.O2.O2...... -3.933464e-18
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 1.065302e-17
## Offline.Biomass.concentratio.X_offline.X.g.L...1... -6.779168e-18
## Carbon.evolution.rate.CER.g.h. 5.347822e-17
## Viscosity.Viscosity_offline.centPoise. 1.651821e-17
## X1.Raman.spec.recorded 8.109200e-01
## X2.PAT.control.PAT_ref.PAT.ref. -3.264142e-01
## Batch.reference.Batch_ref.Batch.ref. -4.856554e-01
## Batch.ID 6.702834e-18
## Fault.flag 8.978266e-18
## PC34
## Time..h. 0.000000e+00
## Aeration.rate.Fg.L.h. 1.103454e-16
## Sugar.feed.rate.Fs.L.h. 2.165627e-17
## Acid.flow.rate.Fa.L.h. 7.071211e-18
## Base.flow.rate.Fb.L.h. 6.986294e-18
## Heating.cooling.water.flow.rate.Fc.L.h. 5.446834e-18
## Heating.water.flow.rate.Fh.L.h. 1.126582e-17
## Water.for.injection.dilution.Fw.L.h. 8.594579e-05
## Air.head.pressure.pressure.bar. -9.294397e-17
## Dumped.broth.flow.Fremoved.L.h. 1.969398e-18
## Substrate.concentration.S.g.L. 5.621428e-17
## Dissolved.oxygen.concentration.DO2.mg.L. 1.349775e-17
## Penicillin.concentration.P.g.L. 4.973219e-17
## Vessel.Volume.V.L. 5.581056e-18
## Vessel.Weight.Wt.Kg. 6.781326e-17
## pH.pH.pH. -5.788061e-18
## Temperature.T.K. -1.489377e-17
## Generated.heat.Q.kJ. 3.749055e-17
## carbon.dioxide.percent.in.off.gas.CO2outgas... -2.374544e-18
## PAA.flow.Fpaa.PAA.flow..L.h.. 1.864356e-17
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 5.646835e-17
## Oil.flow.Foil.L.hr. 1.617641e-17
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1... -2.025487e-17
## Oxygen.Uptake.Rate.OUR..g.min...1... -2.835681e-17
## Oxygen.in.percent.in.off.gas.O2.O2...... 2.127028e-18
## Offline.Penicillin.concentration.P_offline.P.g.L...1... -1.726409e-17
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 9.899569e-18
## Carbon.evolution.rate.CER.g.h. 2.851237e-17
## Viscosity.Viscosity_offline.centPoise. -2.388844e-17
## X1.Raman.spec.recorded 9.190928e-02
## X2.PAT.control.PAT_ref.PAT.ref. -7.486074e-01
## Batch.reference.Batch_ref.Batch.ref. 6.566122e-01
## Batch.ID 7.514175e-19
## Fault.flag 4.012139e-18pca$x## PC1 PC2 PC3 PC4 PC5
## [1,] -4.856981 0.286039318 -3.167108725 1.086529787 0.9960426524
## [2,] -4.568612 0.216107212 -4.421660395 0.398151859 0.5158896563
## [3,] -4.374270 0.119649913 -4.847848921 -0.558824610 0.2037943658
## [4,] -4.108053 0.044754039 -5.151540707 -1.270092145 -0.0785613337
## [5,] -3.711520 2.385509601 -5.337098323 -2.041766339 -0.4463138432
## [6,] -3.758451 -0.019436735 -5.474794022 -1.935408052 -0.5084295896
## [7,] -3.709848 -0.012463956 -5.488350570 -1.865546151 -0.6428690365
## [8,] -3.691217 0.002562939 -5.456567075 -1.708104358 -0.7657935159
## [9,] -3.831441 0.154907762 -5.267703190 0.094574055 -0.2466408307
## [10,] -3.861637 0.195145585 -5.183403590 0.560944097 -0.2565561770
## [11,] -3.314913 0.143932909 -4.724686295 0.892225541 -0.2284598266
## [12,] -3.408300 0.138919214 -4.559203702 0.855493334 -0.2316327497
## [13,] -3.467702 0.108669687 -4.378559270 0.566613893 -0.2652835426
## [14,] -3.483273 0.071911250 -4.287724474 0.182749281 -0.3122391268
## [15,] -3.438707 0.042979891 -4.279759626 -0.117479582 -0.3520170696
## [16,] -3.344062 0.033984010 -4.245073017 -0.180169865 -0.3030422774
## [17,] -3.305345 0.052353972 -4.219058188 0.022344559 -0.2835774379
## [18,] -3.316693 0.084450677 -4.143289107 0.370439115 -0.2450350582
## [19,] -3.403649 0.113575356 -4.009979508 0.658421958 -0.2111449649
## [20,] -3.472514 0.114527896 -3.791724709 0.716728124 -0.2049983667
## [21,] -3.859052 0.099656192 -3.098183330 0.517453993 -0.1889106097
## [22,] -3.927427 0.071502346 -2.983175229 0.166758776 -0.1652611453
## [23,] -3.920517 0.043180003 -2.911819999 -0.139013401 -0.2053341434
## [24,] -3.862111 0.031868285 -2.907430175 -0.246806260 -0.2230432443
## [25,] -3.826230 0.046762559 -2.872960626 -0.095297660 -0.1450445691
## [26,] -4.231474 0.088598680 -2.145676841 0.233104208 0.0139109614
## [27,] -4.258687 0.109453236 -1.968015129 0.516019647 0.0433157050
## [28,] -4.383042 0.119012336 -1.760896167 0.579030555 0.1158800202
## [29,] -4.480434 0.104409061 -1.555827661 0.421518193 0.0936866913
## [30,] -4.528685 0.078144699 -1.440110249 0.150492359 -0.0081324029
## [31,] -4.490913 0.046391831 -1.337390106 -0.132299498 -0.0455306247
## [32,] -4.468840 0.034402609 -1.287964686 -0.280223808 -0.0005006356
## [33,] -4.460963 0.043250738 -1.263874041 -0.214277206 -0.0026628827
## [34,] -4.438778 0.063648472 -1.186362691 0.035904266 0.0224924249
## [35,] -4.474592 0.083982757 -1.007484573 0.299219613 -0.0154055567
## [36,] -4.533340 0.092243780 -0.758695127 0.443328726 -0.0007958397
## [37,] -4.623486 0.085848312 -0.548900240 0.384516190 -0.0093107270
## [38,] -4.718987 0.069994114 -0.366780059 0.186193156 -0.0294316320
## [39,] -4.708832 0.043432824 -0.199139147 -0.031976430 -0.0594060972
## [40,] -4.741828 0.030860244 -0.123501358 -0.221792095 -0.0207508459
## [41,] -4.429143 0.017941518 -0.473797432 -0.216550980 -0.0332604257
## [42,] -4.414203 0.028131380 -0.465171965 -0.132032706 0.0300117766
## [43,] -4.429832 0.046996483 -0.361009401 0.077129452 0.0486187519
## [44,] -4.509206 0.066097829 -0.169342450 0.254362681 0.1345097786
## [45,] -4.585047 0.071903879 0.051159130 0.322734691 0.2017111798
## [46,] -4.676473 0.071361449 0.286904771 0.326503372 0.1977733664
## [47,] -4.786548 0.067176698 0.476251959 0.234653551 0.2471534906
## [48,] -4.857457 0.053453838 0.695137731 0.079092026 0.2917018802
## [49,] -4.886236 0.034241003 0.873565024 -0.117970018 0.3234307810
## [50,] -4.878609 0.018602102 1.051763335 -0.237745781 0.2986027244
## [51,] -4.903928 0.017111554 1.212486356 -0.255806837 0.2860042159
## [52,] -4.919056 0.021689488 1.359989436 -0.192838302 0.2836978121
## [53,] -4.940566 0.026929962 1.573763875 -0.081525553 0.2248181216
## [54,] -4.981071 0.031299883 1.807895559 0.007366967 0.2276838968
## [55,] -5.077694 0.035971640 2.005037890 0.026762521 0.2267049950
## [56,] -5.123709 0.028357934 2.229269749 0.018634188 0.0779345712
## [57,] -5.136221 0.018337976 2.418900238 0.039845509 -0.1896330617
## [58,] -5.132945 0.008106047 2.614215205 0.029704610 -0.2461611895
## [59,] -5.157023 0.001610077 2.743930563 0.001577062 -0.3167240857
## [60,] -4.933270 3.246328697 2.868845974 -0.347707465 -0.5719213934
## [61,] -5.002309 -0.030519676 2.712537011 -0.155423786 -0.5311869361
## [62,] -4.738995 -0.057040936 1.801562839 -0.377284499 -0.9567964354
## [63,] -4.201769 -0.093075806 0.557876753 -0.563414042 -1.4021484046
## [64,] -3.716412 0.013995849 -0.225828806 -1.856076040 6.6390386471
## [65,] -4.457116 0.005046865 0.890463665 -0.789741958 1.7567321531
## [66,] -4.237534 0.037681472 0.537951881 0.115925281 0.4788084353
## [67,] -4.152236 0.066479364 0.444205244 0.742644064 -0.1048643829
## [68,] -4.164992 0.068028083 0.505192405 0.985643631 -0.5192590326
## [69,] -4.195870 0.039575963 0.593416652 0.847814651 -0.8460034790
## [70,] -4.238823 0.001290017 0.566403475 0.453429793 -1.0020927084
## [71,] -4.041191 0.027863406 0.199914369 -0.895211644 4.3246900823
## [72,] -4.488515 -0.035718673 0.977319116 -0.820282310 1.1435573789
## [73,] -4.239395 -0.059059762 0.673855156 -0.715784626 0.3280331726
## [74,] -4.059799 -0.045247902 0.467636985 -0.402114059 0.0290497769
## [75,] -3.968710 -0.012922980 0.351700065 0.056003158 -0.1789446389
## [76,] -3.982340 0.019143791 0.358923389 0.446362724 -0.2566626717
## [77,] -4.007046 0.028461318 0.427765476 0.632091160 -0.3636058010
## [78,] -4.091471 0.015221940 0.528967874 0.495329263 -0.4415110511
## [79,] -4.098252 -0.018273608 0.538810641 0.165373649 -0.5416203249
## [80,] -4.058900 -0.051051868 0.490332464 -0.167017696 -0.6502918592
## [81,] -4.193346 -0.086308900 2.537879353 -0.207673378 -0.0875457154
## [82,] -4.360608 -0.048369881 3.018185039 0.068086341 0.3297141433
## [83,] -4.473604 -0.028399450 3.292883021 0.251568029 0.4608307344
## [84,] -4.588520 -0.028465282 3.572204568 0.248016473 0.5128461971
## [85,] -4.676065 -0.040750399 3.741047394 0.113691358 0.4875350917
## [86,] -4.736589 -0.060150180 3.859502844 -0.087701823 0.3797639458
## [87,] -4.733657 -0.081277839 3.907621285 -0.270729132 0.2203196309
## [88,] -4.696474 -0.098968475 3.960578446 -0.397568256 0.0670988662
## [89,] -4.607533 -0.113417495 3.974046171 -0.466076519 -0.0131734354
## [90,] -4.559522 -0.114581124 3.937940889 -0.464894383 -0.0810576921
## [91,] -4.508957 -0.108099971 3.967608292 -0.344860407 -0.1425182674
## [92,] -4.491039 -0.092501437 3.987005450 -0.160372087 -0.1244933051
## [93,] -4.514015 -0.077219544 4.034064245 0.016017705 -0.1717280582
## [94,] -4.522951 -0.072827522 4.073821388 0.142655518 -0.3687003415
## [95,] -4.529593 -0.077917423 4.121713847 0.162080823 -0.4971838832
## [96,] -4.531550 -0.091867503 4.190435221 0.085619352 -0.6310593910
## [97,] -4.492019 -0.106886716 4.189340456 0.009532854 -0.7702387678
## [98,] -4.462595 -0.122317517 4.205273670 -0.111857328 -0.8436532070
## [99,] -4.460064 -0.130867918 4.258666838 -0.224841074 -0.7848737201
## [100,] -4.424564 -0.135442016 4.243959697 -0.283660022 -0.7267018835
## [101,] 4.916351 -0.854079668 0.783361364 -2.251121951 0.8919800811
## [102,] 4.747088 -0.906941677 0.816633911 -2.332462321 -1.0882204634
## [103,] 5.052825 -0.888271370 0.598674418 -3.226951290 2.6766508758
## [104,] 4.605943 -0.972939763 0.901613600 -3.470080940 -0.4298838481
## [105,] 4.711115 -1.040549605 0.612615885 -3.917215189 -1.5569738538
## [106,] 4.970053 -1.060510357 0.279050941 -4.899678186 0.7445147806
## [107,] 4.726742 -1.136323772 0.402884534 -5.208787166 -1.5250084573
## [108,] 5.065794 -1.129340207 0.059255365 -6.473158259 2.6996708665
## [109,] 4.570992 -1.214522526 0.476815167 -6.610983173 -0.7681311342
## [110,] 4.693720 -1.278001293 0.146075480 -6.975473677 -1.9746163179
## [111,] 4.561367 -1.038844095 -0.178553186 -4.223363225 -2.6427413201
## [112,] 4.718175 -0.992941701 -0.293091695 -4.271292982 -0.9864303799
## [113,] 4.606146 -0.998597089 -0.293329925 -3.842051347 -2.7008995989
## [114,] 4.714785 -0.944870416 -0.291910367 -4.073685417 -0.3627327181
## [115,] 4.157154 -0.636610482 0.224724638 0.220098662 -1.0259159068
## [116,] 4.417509 -0.556757885 0.102148636 -0.085808982 3.0244798610
## [117,] 3.931124 -0.561678181 0.565014761 0.621810622 0.0112191256
## [118,] 4.014321 -0.548905917 0.340384797 1.086765345 -0.8676702907
## [119,] 4.265134 -0.500694742 0.128034117 0.917741123 1.7408540909
## [120,] 3.911598 -0.519048361 0.451668748 1.271280468 -0.3595761616
## [121,] 3.942642 -0.539970255 0.325531706 1.323199068 -1.1474350806
## [122,] 4.106280 -0.534691318 0.248053322 0.855777440 0.7432539396
## [123,] 3.934363 -0.575541330 0.370593455 0.885962278 -0.9600887755
## [124,] 4.217976 -0.550314110 0.194138882 0.144027919 2.4420173991
## [125,] 3.890037 -0.591746967 0.510590423 0.387046591 -0.2270501120
## [126,] 4.056084 -0.603714873 0.272195262 0.581053735 -1.0527176821
## [127,] 4.347986 -0.556382707 -0.035151311 0.421317164 1.2942634809
## [128,] 4.104976 -0.557123088 0.189657793 0.939995493 -0.6132629482
## [129,] 4.182210 -0.549093402 0.025145090 1.302820970 -1.2905033316
## [130,] 5.643394 17.763983425 0.476269875 -0.303535305 -0.0841317939
## [131,] 4.070640 -0.539919291 0.085836219 1.325616103 -1.1903380152
## [132,] 4.270573 -0.512445170 -0.020738020 0.606818532 2.1646078302
## [133,] 3.901872 -0.564553159 0.297392640 0.692205240 -0.4008301927
## [134,] 4.066006 -0.599873745 0.097877522 0.656040637 -1.2496214738
## [135,] 4.359243 -0.568611789 -0.146076544 0.278305573 1.2543381365
## [136,] 4.131306 -0.578602618 0.071568968 0.729401972 -0.8425088524
## [137,] 4.453952 -0.497961363 -0.143609824 0.307292587 3.5806691639
## [138,] 3.931272 -0.514222929 0.365558174 0.972507554 0.3316839589
## [139,] 4.005623 -0.525989716 0.245311192 1.265071038 -0.7213361380
## [140,] 4.071683 -0.542114144 0.022064625 1.302157552 -1.3139243471
## [141,] 4.268126 -0.545196108 -0.091229392 0.804829766 0.4012109071
## [142,] 4.168377 -0.590605484 -0.190481265 0.813669518 -1.3187556261
## [143,] 4.374987 -0.569196312 -0.266187655 0.343423012 0.9679411571
## [144,] 4.224085 -0.587993073 -0.090080265 0.696904090 -0.9015220886
## [145,] 4.483561 -0.518783293 -0.231401809 0.369587983 2.7356347877
## [146,] 4.026802 -0.522485074 0.165646859 0.967800034 0.1162069633
## [147,] 4.099801 -0.526212750 0.044261020 1.273111486 -0.7053515530
## [148,] 4.173682 -0.539524545 -0.108552805 1.371429129 -1.2953723626
## [149,] 4.315685 -0.534128941 -0.184986821 0.965005220 0.3391784074
## [150,] 4.191308 -0.576380621 -0.200435353 0.987631499 -1.2980346940
## [151,] 4.364419 -0.561644253 -0.233559555 0.478721774 0.8580014053
## [152,] 4.196928 -0.589732347 -0.035596191 0.699387592 -0.9690826797
## [153,] 4.456545 -0.531437441 -0.216503315 0.273026351 2.5222020419
## [154,] 4.065011 -0.542404182 0.151299073 0.826714123 -0.1072482904
## [155,] 4.158048 -0.542191244 0.034880503 1.174599560 -0.9135646298
## [156,] 4.343386 -0.503921608 -0.139269027 0.936301390 1.3637805242
## [157,] 4.069762 -0.528619360 0.094866091 1.179536192 -0.5115317308
## [158,] 4.127020 -0.550986395 -0.027289616 1.200637191 -1.2253105776
## [159,] 4.293720 -0.549092668 -0.058026273 0.782094245 0.3947387371
## [160,] 4.165024 -0.581016618 0.031761049 0.879571308 -1.1728377660
## [161,] 4.382380 -0.546498857 -0.081357705 0.330811295 1.8091704759
## [162,] 4.105452 -0.574013160 0.210631504 0.681491920 -0.5423827381
## [163,] 4.194322 -0.574265689 0.042147844 0.937688763 -1.2716265087
## [164,] 4.421453 -0.535807960 -0.048810985 0.791742170 0.8610904411
## [165,] 4.164636 -0.541716842 0.116817126 1.187741551 -0.9244098496
## [166,] 4.412331 -0.490505196 0.001761828 0.665790054 2.7944338924
## [167,] 3.958752 -0.528615466 0.448764925 0.965004959 0.0588174388
## [168,] 4.013026 -0.553982233 0.306137247 0.996790065 -0.8669574864
## [169,] 4.276838 -0.538179662 0.094216173 0.441153780 1.6915215485
## [170,] 4.058089 -0.573986953 0.311427322 0.629876310 -0.3571781906
## [171,] 4.181513 -0.584575241 0.143685226 0.793191635 -1.0751538069
## [172,] 4.402465 -0.551363868 -0.018043645 0.642354387 0.7653799350
## [173,] 4.198172 -0.553529360 0.121591308 1.033831143 -0.8059721585
## [174,] 4.399579 -0.500291193 -0.002029387 0.699283106 2.2470570703
## [175,] 4.042607 -0.525801679 0.338029781 1.059474981 -0.0788284244
## [176,] 4.088069 -0.542436465 0.193016202 1.158024480 -0.8981793832
## [177,] 4.286362 -0.529906990 0.010905743 0.717793802 1.0896918545
## [178,] 4.119190 -0.569816917 0.175185193 0.802801848 -0.6884279763
## [179,] 4.256928 -0.590072960 -0.033684511 0.842111808 -1.3272983981
## [180,] 4.418281 -0.567498573 -0.134745477 0.661921199 0.0644455360
## [181,] 4.352942 -0.577061298 -0.189444882 1.028033344 -1.4323724422
## [182,] 4.496677 -0.533166211 -0.178180592 0.872935813 0.6642154199
## [183,] 4.252941 -0.541375980 -0.025711003 1.236907353 -1.0454443313
## [184,] 4.504030 -0.497979750 -0.136814523 0.748101234 2.3120396446
## [185,] 4.054377 -0.533846556 0.261117636 1.009096080 -0.3518842639
## [186,] 4.145439 -0.562950471 0.115396378 1.016456901 -1.1957768409
## [187,] 4.411757 -0.546176555 -0.097580847 0.580129474 1.0515223282
## [188,] 4.200218 -0.572006491 0.054301779 0.815087146 -0.8971112163
## [189,] 4.550432 -0.518861109 -0.142103800 0.301373942 2.9430819336
## [190,] 5.401743 17.278781485 0.788839873 -0.626618791 -0.4579676967
## [191,] 4.179360 -0.545209642 0.125531631 1.092569351 -0.8619907023
## [192,] 4.414989 -0.507850853 -0.067608118 0.785284431 1.6598954466
## [193,] 4.118321 -0.535306411 0.215138521 1.058122219 -0.4439306924
## [194,] 4.218644 -0.558020484 0.032261489 1.103586868 -1.1727059927
## [195,] 4.426192 -0.548715152 -0.079397519 0.741645233 0.5384378107
## [196,] 4.242722 -0.571310918 0.013725282 0.909757490 -1.0961123068
## [197,] 4.539485 -0.533972166 -0.135575968 0.444707012 1.9878713667
## [198,] 4.187865 -0.552581984 0.130909387 0.854572422 -0.4479262393
## [199,] 4.317865 -0.559840896 -0.034241751 1.126836481 -1.2489203503
## [200,] 5.819809 17.221573360 0.307135960 -0.501276541 0.2862917021
## PC6 PC7 PC8 PC9 PC10
## [1,] -0.133812084 0.511059210 -0.159111634 2.232329432 1.357691851
## [2,] -0.126451317 1.230433419 1.213627936 0.790418411 0.892232683
## [3,] -0.061331835 1.779419025 1.864981438 0.098798364 0.120014173
## [4,] -0.066931154 1.674312144 1.820304547 0.005049883 -0.726525276
## [5,] 0.295199724 1.314028828 1.621776086 0.226903282 -0.958302292
## [6,] 0.652736282 0.661445866 0.833262939 0.601044327 -0.803177291
## [7,] 1.023727724 0.259153031 0.340511558 0.901992398 -0.372929712
## [8,] 1.400671804 -0.101449494 -0.154279230 1.198025231 0.165481612
## [9,] -0.215061761 0.272052821 -0.155981686 1.177736817 -0.306798222
## [10,] -0.229100720 0.138988700 -0.481299630 1.350460937 0.047927587
## [11,] -0.316089848 -0.240270622 -0.835607055 0.486587480 0.609151654
## [12,] -0.276430914 0.101350902 -0.538863521 0.256198253 0.780184694
## [13,] -0.230144897 0.488391705 -0.131372414 -0.046414055 0.753670020
## [14,] -0.200644889 0.736228257 0.203596561 -0.250876618 0.548706319
## [15,] -0.202815785 0.727515409 0.312203057 -0.285587876 0.284385876
## [16,] -0.217088531 0.495833262 0.150288098 0.007277605 0.044940408
## [17,] -0.256149528 0.151637674 -0.199135811 0.302930251 0.081310836
## [18,] -0.285709903 -0.106387921 -0.523201007 0.564159568 0.299609034
## [19,] -0.284956597 -0.118813617 -0.626350821 0.694275054 0.579988720
## [20,] -0.262623133 0.078377184 -0.478420821 0.561396342 0.796642763
## [21,] -0.141089621 0.349959931 -0.588039862 0.212269606 0.063829250
## [22,] -0.108397400 0.603788759 -0.215033444 0.073716383 -0.089289651
## [23,] -0.099862296 0.665527494 -0.056597968 0.034331134 -0.316004114
## [24,] -0.123364838 0.478789799 -0.151696542 0.149101125 -0.486614755
## [25,] -0.167635199 0.118103460 -0.419969751 0.428392634 -0.465158044
## [26,] -0.183385654 -0.962103424 -1.086423176 -0.616112174 -0.796425950
## [27,] -0.196464393 -1.038512121 -1.211728546 -0.560182601 -0.501355018
## [28,] -0.175022045 -0.866823124 -1.028765014 -0.582300894 -0.288304207
## [29,] -0.139237487 -0.557453096 -0.702841239 -0.760986741 -0.230362922
## [30,] -0.104015699 -0.261418794 -0.409497540 -0.951158720 -0.337227398
## [31,] -0.094853633 -0.185414694 -0.257960136 -1.071897600 -0.510189531
## [32,] -0.109961604 -0.326656422 -0.268430018 -0.953742375 -0.664654504
## [33,] -0.141140058 -0.573615164 -0.453838770 -0.717427760 -0.707975618
## [34,] -0.171086874 -0.833465663 -0.749611463 -0.500611153 -0.567936657
## [35,] -0.175379228 -0.894997975 -0.948741648 -0.375418479 -0.331899204
## [36,] -0.162653634 -0.809743881 -0.948794531 -0.396027817 -0.082861609
## [37,] -0.127930074 -0.548650957 -0.740025092 -0.518486878 0.035762786
## [38,] -0.083168941 -0.247723991 -0.471169453 -0.619212238 0.020445204
## [39,] -0.072112580 -0.134972123 -0.288606728 -0.759683185 -0.053694530
## [40,] -0.072142147 -0.144341990 -0.161245923 -0.692715482 -0.186639066
## [41,] -0.123408040 -0.458399227 0.016671694 -0.833837855 -0.265729664
## [42,] -0.159944868 -0.719814174 -0.093940374 -0.659288025 -0.243082975
## [43,] -0.181978201 -0.898437021 -0.280593950 -0.476126813 -0.093828911
## [44,] -0.185854948 -0.953072525 -0.322083350 -0.326468941 0.122015996
## [45,] -0.185637058 -0.902036232 -0.188837806 -0.342149634 0.320577201
## [46,] -0.166708017 -0.727651518 -0.006863884 -0.407566964 0.481953184
## [47,] -0.148339205 -0.547762645 0.274798542 -0.464948197 0.565140870
## [48,] -0.132725577 -0.404549043 0.533391503 -0.531498679 0.591065095
## [49,] -0.137071135 -0.365545563 0.771975981 -0.595849488 0.542853896
## [50,] -0.147967879 -0.410931940 0.834140845 -0.592562420 0.498284051
## [51,] -0.160295206 -0.509913601 0.792358988 -0.456904479 0.494579988
## [52,] -0.174867263 -0.631002213 0.693121277 -0.321058174 0.552474097
## [53,] -0.175886216 -0.672501856 0.560199175 -0.221240831 0.678746313
## [54,] -0.175275893 -0.681858116 0.521453574 -0.165575594 0.837944995
## [55,] -0.156104683 -0.567481676 0.598760379 -0.109475243 0.951043786
## [56,] -0.136728703 -0.397209965 0.644508440 -0.198146146 1.049549944
## [57,] -0.087750712 -0.108191326 0.537521099 -0.326417448 1.134069044
## [58,] -0.039308883 0.099245095 0.458718852 -0.401549819 1.224025497
## [59,] -0.013397789 0.249763451 0.478407894 -0.453739928 1.268282063
## [60,] 0.011280779 0.594942011 0.774035356 -0.618204860 1.308698826
## [61,] 0.060538681 0.620607511 0.511766966 -0.485436699 0.908848019
## [62,] 0.006924106 0.669582071 0.661589328 -0.988229145 0.315334500
## [63,] -0.022862685 0.656413863 0.503073827 -1.341458447 -0.703686659
## [64,] 0.786227044 -0.119638100 0.419231024 -0.326232040 -0.803137149
## [65,] -0.554984989 -2.774757097 1.862539383 0.718606275 -0.761939629
## [66,] -0.453378160 -2.254314711 0.305585117 0.663661484 -0.497838718
## [67,] -0.316061820 -1.625436301 -0.555281797 0.427527833 -0.079993153
## [68,] -0.175505711 -0.816806201 -0.778015821 -0.018895672 0.247628132
## [69,] -0.035658309 0.063128317 -0.615332815 -0.573481157 0.343182942
## [70,] 0.078098036 0.771802898 -0.261838238 -0.978924454 0.167553578
## [71,] 0.653566888 0.755275276 0.402535163 -0.636803004 -0.047105436
## [72,] -0.187116194 -0.710012393 1.844051181 -0.305446678 -0.395292992
## [73,] -0.139475116 -0.506178411 0.972649308 -0.354620650 -0.693421546
## [74,] -0.120239787 -0.638438700 0.144386579 -0.172104303 -0.733731230
## [75,] -0.116417935 -0.775921561 -0.522266066 0.009751251 -0.560996619
## [76,] -0.093059726 -0.729868182 -0.873091188 0.101744576 -0.279541250
## [77,] -0.057593326 -0.475195640 -0.896307205 -0.072718935 -0.037991275
## [78,] 0.005452354 -0.031515548 -0.621734031 -0.314030362 0.013712466
## [79,] 0.056279681 0.350672893 -0.300474887 -0.610632704 -0.149001788
## [80,] 0.076547506 0.509478869 -0.128489009 -0.763382858 -0.422230068
## [81,] 0.338523916 0.611206610 -0.826144913 0.562123415 -0.959729223
## [82,] 0.249401579 0.077680233 -0.787026569 1.067488934 -0.614334998
## [83,] 0.197484224 -0.076870987 -0.575810273 1.140543992 -0.319016572
## [84,] 0.200230123 0.072378761 -0.258674514 1.038543907 -0.109733550
## [85,] 0.218734975 0.328466668 0.103983211 0.849719789 -0.046924885
## [86,] 0.238075640 0.573398059 0.402369886 0.667765540 -0.091565272
## [87,] 0.266430716 0.780194758 0.497218077 0.539273100 -0.210682012
## [88,] 0.280435487 0.849723745 0.446373996 0.506020940 -0.334981327
## [89,] 0.270886791 0.757518627 0.306935072 0.508475430 -0.448776668
## [90,] 0.261299524 0.637707855 0.130861807 0.632044496 -0.549841044
## [91,] 0.237492844 0.445194719 -0.107371223 0.768429288 -0.531952802
## [92,] 0.219823890 0.287876197 -0.309534309 0.905147092 -0.430915701
## [93,] 0.221695462 0.288246804 -0.417661098 0.970067137 -0.290450591
## [94,] 0.232609825 0.438596166 -0.460180676 0.845358756 -0.165888364
## [95,] 0.277970761 0.717652420 -0.468932982 0.678032838 -0.084024802
## [96,] 0.332910084 1.034690417 -0.440834759 0.505919937 -0.074105685
## [97,] 0.365979608 1.244352700 -0.434548451 0.333769999 -0.111729812
## [98,] 0.397450760 1.394075646 -0.432678970 0.258176208 -0.197699844
## [99,] 0.409002842 1.386941058 -0.425880258 0.335266806 -0.280862081
## [100,] 0.390964763 1.252014660 -0.445663693 0.414105111 -0.369550746
## [101,] -2.974423742 0.885186199 -1.330464554 0.052691150 0.830610488
## [102,] -3.352980407 0.342718553 -0.965078345 0.272320914 0.322668444
## [103,] -2.787850784 0.609439190 -1.013080729 0.065512430 0.269723879
## [104,] -3.046649151 -0.322438736 0.053295322 0.396677274 0.111475822
## [105,] -2.543002283 0.239225111 -0.480306818 0.041078801 0.025244772
## [106,] -1.698289159 0.525123911 -0.766883565 -0.145701914 0.101609129
## [107,] -1.696549286 0.030833002 -0.222327820 -0.037663592 0.003276766
## [108,] -0.681393327 0.100477815 -0.340916273 -0.092452625 0.184999555
## [109,] -1.031938652 -0.993311605 0.823226513 0.281446262 0.074173348
## [110,] -0.531958663 -0.428043948 0.211504073 -0.096787813 0.024464119
## [111,] 3.247670687 -0.403295668 0.363320780 -0.433859359 -0.471279744
## [112,] 3.937015708 -0.473045202 -0.352999137 -0.253066826 0.217731047
## [113,] 4.079302143 -0.844302906 -0.712270860 0.099730028 0.683256966
## [114,] 4.776368228 -1.135415196 -1.127355408 0.381620987 1.382794952
## [115,] -0.018644570 -0.066767309 0.151323307 -0.099499702 -0.658059738
## [116,] 0.497319255 -0.114532956 -0.161436004 0.049343628 -0.236990994
## [117,] -0.216371919 -1.143125679 0.671968331 0.567600814 -0.138420661
## [118,] -0.155116507 -0.680929320 -0.081076175 0.394075174 0.002551944
## [119,] 0.296345381 -0.273909756 -0.516941323 0.223121499 0.321705911
## [120,] -0.125080058 -0.577416389 0.204835072 0.318831445 0.393604321
## [121,] -0.015443355 0.229029033 -0.048939508 -0.136093214 0.383598821
## [122,] 0.336864443 0.706427840 -0.074988902 -0.433364430 0.428103708
## [123,] 0.028670707 0.517715116 0.446144292 -0.450265515 0.210203879
## [124,] 0.515836334 0.679143875 0.351941942 -0.484373975 0.165448117
## [125,] -0.115639741 -0.282020576 1.150235421 -0.065265639 -0.126207853
## [126,] -0.076277492 -0.022443217 0.392880577 -0.160673842 -0.273536822
## [127,] 0.303020992 0.052940027 -0.243564159 -0.084744141 -0.164652675
## [128,] -0.128648796 -0.606958982 0.035049398 0.274484651 -0.104755350
## [129,] -0.062388042 -0.163780160 -0.552831775 0.064900118 0.034582872
## [130,] 0.160891097 0.252721092 -0.786098572 -0.212156350 0.195386724
## [131,] -0.014362865 0.196873921 -0.211510872 -0.183502778 0.244018868
## [132,] 0.473678809 0.529278193 -0.070420309 -0.352083403 0.325640330
## [133,] -0.111603153 -0.151789313 1.001784909 -0.133534290 0.030859823
## [134,] -0.055339625 0.285848464 0.500481045 -0.423878740 -0.218534517
## [135,] 0.332890167 0.355295768 0.012559727 -0.364173697 -0.225527399
## [136,] -0.108715646 -0.321941233 0.225530179 0.044735011 -0.299028187
## [137,] 0.478121506 -0.346874279 -0.209924958 0.248186240 0.026019753
## [138,] -0.308485544 -1.458760913 0.840261872 0.729318123 0.088839826
## [139,] -0.212133524 -0.691703380 0.248297520 0.311751913 0.186219967
## [140,] -0.058275286 0.149440915 -0.128063855 -0.130403723 0.154226146
## [141,] 0.286944468 0.649173635 -0.190125966 -0.478317013 0.124216670
## [142,] 0.056093410 0.696723048 0.037865785 -0.459709641 -0.219778304
## [143,] 0.352973028 0.612352684 -0.074898508 -0.442907488 -0.250445759
## [144,] -0.071731287 -0.100091628 0.164538365 -0.121050964 -0.364330859
## [145,] 0.394855043 -0.217382705 -0.232113738 0.116673290 -0.097517412
## [146,] -0.253006066 -1.178748392 0.583608929 0.646290718 -0.037760478
## [147,] -0.198164864 -0.657255865 0.108463570 0.311149538 0.089515464
## [148,] -0.070403626 0.075516064 -0.260232504 -0.123077692 0.123714157
## [149,] 0.244555416 0.526490475 -0.280819095 -0.417325229 0.167457795
## [150,] 0.041053245 0.662295950 -0.036952301 -0.438000834 -0.093303043
## [151,] 0.340879759 0.704787627 -0.055449467 -0.496389280 -0.124919457
## [152,] -0.045963742 0.149914539 0.258325182 -0.235524632 -0.300417958
## [153,] 0.405573723 0.053109521 -0.062092318 -0.033417559 -0.149712550
## [154,] -0.222422070 -0.903666418 0.615231753 0.473909563 -0.162770855
## [155,] -0.169306842 -0.472338964 -0.010801182 0.248650261 -0.048941665
## [156,] 0.239507436 -0.043692333 -0.319230267 0.100473266 0.169877750
## [157,] -0.131063584 -0.310639547 0.304188385 0.153967225 0.150527999
## [158,] -0.039971488 0.342327587 0.011739082 -0.219119086 0.088173636
## [159,] 0.260507491 0.684960837 -0.093127768 -0.440801730 0.093103841
## [160,] -0.009993242 0.480662748 0.196318938 -0.384222716 -0.101271538
## [161,] 0.410310143 0.552013110 0.023105556 -0.304290344 -0.076932021
## [162,] -0.139504051 -0.288928592 0.601259781 0.080429111 -0.224933749
## [163,] -0.091897319 0.029014225 -0.048051142 0.004978098 -0.247598829
## [164,] 0.252978582 0.173151900 -0.507327567 -0.022461861 -0.028683882
## [165,] -0.105609321 -0.191986260 -0.126497107 0.182702391 0.003695192
## [166,] 0.425662345 0.057835460 -0.240107855 0.107378505 0.269413968
## [167,] -0.221437931 -0.709989730 0.906232616 0.388046080 0.176428531
## [168,] -0.141861776 -0.040003418 0.547461895 0.035471652 0.058908647
## [169,] 0.319653374 0.411768816 0.255031979 -0.125862499 0.034578532
## [170,] -0.135174210 -0.202560198 0.807575943 0.102250488 -0.169704571
## [171,] -0.088674045 0.102669975 0.200781940 -0.025325366 -0.262658952
## [172,] 0.220841291 0.221964083 -0.279200478 -0.018741606 -0.148932234
## [173,] -0.102471675 -0.187885990 -0.062476384 0.243096139 -0.128825925
## [174,] 0.345960626 0.006809743 -0.294285443 0.248480728 0.126347729
## [175,] -0.199784319 -0.652679523 0.568130140 0.467927260 0.117043185
## [176,] -0.122464374 -0.017434385 0.232700442 0.118904177 0.081562237
## [177,] 0.258168372 0.451797277 0.056844447 -0.113633036 0.091200296
## [178,] -0.084995181 0.136424796 0.533215887 -0.063343349 -0.111083783
## [179,] -0.029158574 0.490761991 0.053502291 -0.279582233 -0.271726623
## [180,] 0.209373818 0.564407183 -0.304796656 -0.257942549 -0.246323442
## [181,] -0.014605163 0.389279372 -0.451534895 -0.085066172 -0.316526769
## [182,] 0.267757116 0.356732801 -0.673062954 -0.054881153 -0.076369287
## [183,] -0.091447828 -0.028317827 -0.253294606 0.125991935 -0.051047645
## [184,] 0.388900318 0.195707158 -0.333444911 -0.017009377 0.183368147
## [185,] -0.191172126 -0.399152741 0.683725332 0.259565327 0.053512171
## [186,] -0.108203676 0.230245586 0.282545828 -0.095741963 -0.078485936
## [187,] 0.273643928 0.510958552 -0.003772490 -0.259432202 -0.078163673
## [188,] -0.110727037 0.065517428 0.370040930 -0.036568974 -0.249404398
## [189,] 0.427349563 0.124380927 -0.007904646 0.006400032 -0.077315552
## [190,] -0.364455521 -0.849639463 0.881327880 0.436864596 -0.222579039
## [191,] -0.212906065 -0.404951197 0.253566616 0.300750502 -0.111906194
## [192,] 0.248296789 0.052992398 -0.160641614 0.167194079 0.067464906
## [193,] -0.174054846 -0.328063607 0.455793605 0.312185695 0.012347774
## [194,] -0.096214609 0.243535915 0.085894638 -0.054142055 -0.075361509
## [195,] 0.222525944 0.559804698 -0.143654132 -0.253449287 -0.059925591
## [196,] -0.069534141 0.308021564 0.150065280 -0.094895594 -0.225068596
## [197,] 0.364807873 0.364143975 -0.120030553 -0.120808304 -0.114860924
## [198,] -0.201755331 -0.442452658 0.550188131 0.294975952 -0.218001481
## [199,] -0.145789766 -0.027660011 -0.091420804 0.054835800 -0.192941600
## [200,] 0.121514629 0.321258811 -0.436116316 -0.157490875 -0.095872237
## PC11 PC12 PC13 PC14 PC15
## [1,] -0.8768956746 1.0537143274 -0.394210868 -0.0115632047 0.103514222
## [2,] -0.3950234157 1.1874695583 -0.153309369 -0.0248439444 -0.238345195
## [3,] -0.2521545974 0.8518141474 -0.046814096 -0.2438917687 -0.290490348
## [4,] -0.3531127805 0.1334951496 0.086812512 -0.5071297130 -0.244399990
## [5,] -1.0973871208 -1.3042978435 -1.213492660 1.5532878249 -0.152463234
## [6,] -0.6614337408 -0.3174077709 0.126372736 -0.5692337006 -0.120404317
## [7,] -0.7718756465 -0.1636515042 0.101931342 -0.4516614665 -0.088022316
## [8,] -0.8736866097 0.0747198999 0.066504551 -0.3030259948 -0.061974633
## [9,] -0.8753233584 -0.4184851564 0.135931220 -0.4396167554 -0.268765308
## [10,] -0.9417772421 -0.2805756696 0.132602453 -0.3347359495 -0.284556114
## [11,] 0.4484400275 -0.2480385832 0.258674879 0.1876901869 -0.077667748
## [12,] 0.5551771009 -0.0128078889 0.256950401 0.2459981418 -0.074355569
## [13,] 0.6903712817 0.0767370082 0.274820075 0.2368992601 -0.046589865
## [14,] 0.7497984055 0.0009540722 0.307175935 0.1655522580 -0.011973787
## [15,] 0.7466313443 -0.2140607723 0.344091719 0.0745698088 0.022527478
## [16,] 0.7263012668 -0.4111069248 0.344528414 0.0265148254 -0.009230575
## [17,] 0.6163405170 -0.5788424983 0.341181812 0.0061242530 -0.004672412
## [18,] 0.5300880582 -0.5772947295 0.323838089 0.0488702195 -0.012706369
## [19,] 0.4606654263 -0.4258704176 0.299731803 0.1048101096 -0.030592574
## [20,] 0.5649091239 -0.2566942091 0.301017802 0.1709010757 -0.015780814
## [21,] 1.1382573103 0.1693431630 -0.097730494 0.2870460527 0.590673806
## [22,] 1.1661021481 0.1543445717 -0.110588922 0.2041703295 0.603777635
## [23,] 1.1461332919 -0.0294260696 -0.080033002 0.1066453379 0.636928770
## [24,] 1.0973869693 -0.2599121526 -0.051652277 0.0392107911 0.663646692
## [25,] 1.0385337732 -0.4148088302 -0.073795384 0.0167883586 0.666403166
## [26,] -0.0550657815 0.1278777766 -0.420614729 -0.0757302428 -0.101131731
## [27,] 0.0021874416 0.2391810349 -0.420071840 0.0171983525 -0.092514816
## [28,] 0.0227319640 0.4296291319 -0.459050672 0.0469735007 -0.102136699
## [29,] 0.0733355925 0.5405860583 -0.441196244 0.0463029352 -0.080667035
## [30,] 0.0714931658 0.5232098994 -0.385182512 0.0007622182 -0.049116570
## [31,] 0.1553131537 0.3648535170 -0.356068626 -0.0609720141 -0.011020142
## [32,] 0.1246009990 0.1713409541 -0.369577646 -0.1467325278 0.001472422
## [33,] -0.0081651173 -0.0003507332 -0.351336785 -0.1956752681 0.012846800
## [34,] -0.0533099138 -0.0727188571 -0.360517383 -0.1758907287 0.012371951
## [35,] -0.1111548657 -0.0477643805 -0.345370271 -0.1329442057 0.019728046
## [36,] -0.0434561534 0.0587050958 -0.357585519 -0.0795102025 0.031031728
## [37,] 0.0003887523 0.1755209734 -0.364099135 -0.0716291600 0.040390179
## [38,] -0.0236361854 0.2133276049 -0.376646901 -0.1319571737 0.040621401
## [39,] 0.0809657926 0.1314623104 -0.341815732 -0.1572961752 0.083017819
## [40,] 0.0279689677 0.0131679018 -0.353774145 -0.2461684063 0.088893871
## [41,] -0.0473408249 -0.0682047220 -0.120136615 -0.1999881040 -0.064274376
## [42,] -0.0684640573 -0.1957252351 -0.142332682 -0.2374428868 -0.087778044
## [43,] -0.1289153521 -0.2334191685 -0.143381588 -0.2248707040 -0.092266771
## [44,] -0.1609669677 -0.1657875921 -0.187316664 -0.2126042288 -0.109747322
## [45,] -0.0886267682 -0.0546737071 -0.197080673 -0.1708510357 -0.101853316
## [46,] -0.0633587683 0.0440213674 -0.183076556 -0.1516867999 -0.091461897
## [47,] -0.0469122768 0.1459079213 -0.193737212 -0.1625478612 -0.089300103
## [48,] 0.0070395836 0.1631564104 -0.199039687 -0.1914861710 -0.074941569
## [49,] 0.0833703373 0.0988635507 -0.172898660 -0.2220067520 -0.040185823
## [50,] 0.1154743981 -0.0502183635 -0.126054843 -0.2567129591 0.001562455
## [51,] 0.0419307826 -0.1968515134 -0.102820432 -0.3102106539 0.022132962
## [52,] -0.0058152342 -0.3051077146 -0.091266237 -0.3368545975 0.034238901
## [53,] -0.0571224472 -0.3919526402 -0.061947870 -0.3464304943 0.051363322
## [54,] -0.0410788843 -0.4128662194 -0.060869800 -0.3421524409 0.063217183
## [55,] -0.1149345717 -0.3836777552 -0.071931994 -0.3730163830 0.054921291
## [56,] -0.1306785728 -0.4191345460 0.006259582 -0.3706504879 0.094699246
## [57,] -0.1984526197 -0.4939968899 0.088131033 -0.3878754046 0.120310618
## [58,] -0.1450340487 -0.5314349874 0.038848912 -0.4268364871 0.099606717
## [59,] -0.1568911589 -0.5495592718 0.048363652 -0.4489862321 0.100643868
## [60,] -0.7312900166 -1.5550399810 -1.198652357 1.6405745285 0.132184414
## [61,] -0.1315944106 -0.4488435936 0.181625175 -0.3611940365 0.044011721
## [62,] -0.2097531982 -0.2974174206 0.585929951 -0.1122425901 0.204086794
## [63,] -0.5073771031 0.1018139874 1.207043636 0.4191976744 0.338933155
## [64,] 0.0609689811 0.1489236294 -0.019944121 0.0248075625 -0.131693547
## [65,] -0.0580004578 -0.0295946252 0.779297460 0.4023180063 0.359505641
## [66,] -0.4215597289 -0.0929503600 0.699813933 0.3927255477 0.186937118
## [67,] -0.5676270989 0.0858207573 0.675141425 0.4765419849 0.090733386
## [68,] -0.5664521021 0.3645245522 0.684252027 0.5565770254 0.041346813
## [69,] -0.4907351342 0.5822571246 0.697968025 0.5702419194 0.017194230
## [70,] -0.4792380180 0.6893254967 0.660499654 0.4793216253 -0.023471685
## [71,] 0.1298035563 0.9560001987 -0.300020905 0.1518739394 -0.365233121
## [72,] 0.1477105798 0.6510469211 0.374088804 0.3274022592 0.054251827
## [73,] -0.0641890358 0.2396723737 0.355770297 0.1715877418 -0.015614153
## [74,] -0.2578915056 -0.0418796438 0.339216946 0.1116025631 -0.063664429
## [75,] -0.4318872035 -0.1231984061 0.354301800 0.1443474313 -0.099710619
## [76,] -0.5256218450 -0.0013524729 0.316258586 0.1987506733 -0.150677655
## [77,] -0.4741788014 0.2022675062 0.334965506 0.2922253412 -0.160810952
## [78,] -0.4521931604 0.3573793732 0.326977177 0.2808968328 -0.177527615
## [79,] -0.3926180738 0.3757901958 0.353486954 0.2356094603 -0.170445413
## [80,] -0.4008295208 0.2251105808 0.403415226 0.1525155780 -0.146572240
## [81,] 0.1972567812 -0.0258792042 -0.350279750 -0.1313498729 -0.295311913
## [82,] 0.2013699448 0.0688489401 -0.405356330 -0.0560442429 -0.225512489
## [83,] 0.2706424531 0.2576390425 -0.341820238 0.0740069141 -0.163183579
## [84,] 0.3621804043 0.4261155927 -0.314254555 0.1327715210 -0.132951938
## [85,] 0.4183362744 0.5610570352 -0.260707308 0.1640945530 -0.099807845
## [86,] 0.4200262703 0.5695742768 -0.180415379 0.1472597420 -0.059996150
## [87,] 0.3708153320 0.4738843985 -0.115182654 0.0946069964 -0.035050743
## [88,] 0.3056951519 0.2886143856 -0.054574233 0.0290622857 -0.009094552
## [89,] 0.3224821047 0.0937356516 -0.015051635 -0.0039077486 0.021877609
## [90,] 0.2101038391 -0.0798055209 0.007460639 -0.0612377189 0.022327080
## [91,] 0.1474755877 -0.2323608338 0.041956735 -0.0741419411 0.033372608
## [92,] 0.1133987783 -0.2541164716 0.027086149 -0.0566878642 0.023601720
## [93,] 0.0398170856 -0.2123090160 0.037974071 -0.0345163368 0.007452441
## [94,] 0.0008434961 -0.1431430610 0.146041833 0.0385201471 0.042792162
## [95,] 0.0177950396 -0.0720714007 0.152019689 0.0506582280 0.032251064
## [96,] 0.0215100742 -0.0577382301 0.151129901 0.0220409342 0.019099489
## [97,] 0.0463192475 -0.0795041713 0.181596140 0.0126195911 0.020506113
## [98,] 0.0374175422 -0.1590537001 0.168806009 -0.0483248626 0.004013963
## [99,] 0.0146408461 -0.2679885301 0.102231253 -0.1405149528 -0.026657907
## [100,] 0.0166958621 -0.3590483845 0.086082656 -0.1733894601 -0.024828339
## [101,] -0.3943434948 0.3229225571 -0.046857125 0.1148833679 0.153115511
## [102,] -0.3228854022 0.0567118984 -0.104052586 -0.0311290060 0.049961915
## [103,] -0.2059951075 -0.2128277773 0.059743955 -0.0183220777 0.074213171
## [104,] 0.0464983724 0.0830429617 -0.077790147 0.0047370042 0.028151161
## [105,] -0.1108799754 -0.0026887928 -0.017618971 -0.0490390042 -0.039261129
## [106,] -0.1279050170 -0.0854194178 0.066811444 -0.0324888840 -0.035309997
## [107,] 0.0266847395 0.0899411195 0.009637887 -0.0077566639 -0.076304418
## [108,] 0.1541487327 0.0487903796 0.036591187 0.0444459403 -0.058207661
## [109,] 0.4193774302 0.3552008593 -0.029176758 0.1177243018 -0.062516505
## [110,] 0.2639071948 0.2934575070 0.039126334 0.0889787494 -0.134903539
## [111,] 0.2372195856 -0.3618521162 0.094355514 -0.1902788866 0.080743132
## [112,] 0.0383308243 -0.1419944527 0.168596456 0.0013475031 0.161960624
## [113,] 0.1137004178 0.3777440387 -0.251705508 0.0716507082 0.002144610
## [114,] -0.0783100797 0.5636096718 -0.075148184 0.2938350864 0.168053470
## [115,] 0.2056542226 -0.7876347795 0.140847015 -0.1979178901 -0.358781019
## [116,] 0.2496090101 -0.7635052151 0.157554754 -0.0870173998 -0.303364180
## [117,] 0.3808168654 -0.3996538511 0.053749305 0.0174437580 -0.307128412
## [118,] 0.1761914660 -0.3685931782 0.044050488 0.0233878554 -0.378515377
## [119,] 0.1961023436 -0.2863439194 0.051631138 0.1087809753 -0.373799354
## [120,] 0.3586420399 0.1007142022 -0.053028478 0.1805242183 -0.389226816
## [121,] 0.2338476698 0.1864952976 -0.001501916 0.1653768454 -0.411283747
## [122,] 0.2525651825 0.1422624310 0.108035204 0.1824678548 -0.333116627
## [123,] 0.3786204665 0.2336153886 0.043493947 0.1511663872 -0.339298184
## [124,] 0.3390673183 -0.0193464554 0.150312200 0.1105918840 -0.247364893
## [125,] 0.4945493780 0.0126633803 0.045003624 0.0687278335 -0.240671379
## [126,] 0.2896687912 -0.2680069392 0.062216272 -0.0303233537 -0.277873056
## [127,] 0.1193858855 -0.4802252957 0.131649228 -0.0329849566 -0.259394527
## [128,] 0.2123517080 -0.3074076934 -0.004846807 0.0033093170 -0.296441109
## [129,] 0.0759378400 -0.2542602192 0.006109740 0.0297189401 -0.341934510
## [130,] 0.3238504054 0.0768916369 0.404135081 -0.2730394781 -0.469127560
## [131,] 0.0873788987 0.0835399803 0.082105181 0.1456881461 -0.294402567
## [132,] 0.1134487801 0.0427199674 0.196995073 0.1723244593 -0.194202749
## [133,] 0.3491647752 0.2346164631 0.066390029 0.1432780951 -0.198008506
## [134,] 0.2304806566 -0.0354980654 0.121621676 0.0391629544 -0.205205986
## [135,] 0.1165702101 -0.3317615057 0.179947490 -0.0121355382 -0.164229089
## [136,] 0.0929468053 -0.3150133018 0.098034552 -0.0337249339 -0.183256359
## [137,] 0.0625654347 -0.4000897289 0.091645346 0.0139084381 -0.149009853
## [138,] 0.3189042753 0.0184781041 -0.042158116 0.1327072461 -0.147719565
## [139,] 0.1750272634 0.0608438567 0.008247265 0.1412614958 -0.178550513
## [140,] 0.0242699291 0.1174570526 0.019967802 0.0965039624 -0.227184798
## [141,] 0.0096707561 -0.0032564342 0.189361249 0.1059539665 -0.131741952
## [142,] 0.1203837009 0.1039995292 -0.169023604 -0.0725372561 -0.310720971
## [143,] 0.0023045169 -0.2262202512 0.107815451 -0.0538659025 -0.142383027
## [144,] 0.1241057908 -0.2289662520 0.003784577 -0.0603405640 -0.159421427
## [145,] 0.0585673582 -0.3634585196 0.033381919 -0.0256760023 -0.106383376
## [146,] 0.2031595813 0.0036275331 -0.153031255 0.0350426291 -0.148231362
## [147,] 0.1390232199 0.0772012859 -0.106591247 0.0840732308 -0.167956095
## [148,] 0.0280545113 0.1294907695 -0.037581295 0.0907884591 -0.180697943
## [149,] 0.0079079660 0.0826534823 0.114204769 0.1205921723 -0.090566429
## [150,] 0.1051161046 0.2229302639 -0.199123031 -0.0294858170 -0.241983629
## [151,] -0.0084183976 -0.0611066963 0.086814073 -0.0093783791 -0.067332994
## [152,] 0.0810966820 -0.0825095914 -0.010061374 -0.0530638153 -0.077883478
## [153,] -0.0099187203 -0.2721475510 0.047472467 -0.0485223177 -0.015497871
## [154,] 0.1097556101 -0.0368513218 -0.098150160 -0.0118676875 -0.040808293
## [155,] -0.0038496092 -0.0481354667 -0.072006166 0.0058065191 -0.069070025
## [156,] -0.0669097898 -0.0089778631 -0.033757834 0.0464480323 -0.050286938
## [157,] 0.1065228276 0.2814023165 -0.145251813 0.0837662240 -0.071670336
## [158,] -0.0090063261 0.2697702516 -0.096708662 0.0458930818 -0.085130313
## [159,] -0.0353465478 0.1114198031 0.062002984 0.0510276658 0.020194024
## [160,] 0.0174990831 0.1299527092 -0.006599224 0.0014934068 0.002899863
## [161,] -0.1175079652 -0.1164594798 0.123273580 -0.0292694685 0.099002866
## [162,] 0.0500866744 -0.0234538228 -0.013732092 -0.0365750863 0.082614718
## [163,] -0.1714535250 -0.1628386672 -0.009374583 -0.1017898743 0.040954362
## [164,] -0.2292785596 -0.2866305496 0.099064026 -0.0444173117 0.109973715
## [165,] -0.1694043428 -0.0323628009 -0.030877240 -0.0184584873 0.062063291
## [166,] -0.1292319348 -0.0240551545 0.040530500 0.0565033631 0.136330690
## [167,] 0.1813535136 0.3524824198 -0.141348120 0.0993578906 0.120913773
## [168,] -0.0130618699 0.2764511250 -0.069051429 0.0319377437 0.108519430
## [169,] -0.0790781234 0.0994625819 -0.038131835 -0.0320344570 0.137294320
## [170,] 0.1031260689 0.1637159032 -0.162591354 -0.0597063098 0.123864724
## [171,] -0.0837546989 -0.0396569079 -0.120676721 -0.1283338379 0.105621789
## [172,] -0.2084245876 -0.2205101763 -0.018060992 -0.1150686908 0.157792468
## [173,] -0.1754165179 -0.0575428504 -0.155760018 -0.1126430884 0.106415939
## [174,] -0.2517627588 -0.0759002829 -0.066340397 -0.0519711087 0.168805620
## [175,] 0.0441201825 0.2824356142 -0.236176708 0.0160272124 0.143946955
## [176,] -0.1128581851 0.2859722862 -0.174821807 -0.0116108288 0.126117882
## [177,] -0.1853262577 0.1925454807 -0.079327679 -0.0258204883 0.175401827
## [178,] -0.0279226739 0.2523289448 -0.161483707 -0.0549417625 0.170529007
## [179,] -0.1449579435 0.0642419407 -0.132372352 -0.1299979292 0.151168359
## [180,] -0.3451136859 -0.1867564925 0.054325439 -0.1351504260 0.244267669
## [181,] -0.3076070956 -0.0943503865 -0.210448337 -0.2090027406 0.104943945
## [182,] -0.4441981987 -0.2354128205 0.071075510 -0.0961754419 0.265549120
## [183,] -0.3205763852 0.0326976349 -0.084272923 -0.0664952072 0.211813468
## [184,] -0.2836727271 0.0107330104 0.077114301 0.0399369857 0.322554418
## [185,] -0.1225886862 0.3236593599 -0.077364500 0.0336357546 0.300774358
## [186,] -0.2410724528 0.2211666244 -0.051023627 -0.0428624890 0.278489596
## [187,] -0.2687977591 0.0384400369 0.048295963 -0.0489935947 0.340184137
## [188,] -0.2268059878 0.0903198646 -0.053962734 -0.0961017080 0.312321483
## [189,] -0.2594634738 -0.1139997131 0.057183973 -0.0564074438 0.397205728
## [190,] 0.1822999207 0.2984652162 -0.095198696 -0.1310153465 0.189108558
## [191,] -0.2415244802 0.1080217995 -0.119462637 -0.0656131221 0.326828197
## [192,] -0.3417217348 0.0598813714 -0.073204155 -0.0543940698 0.347958877
## [193,] -0.1908788865 0.2960997849 -0.194927785 -0.0415943807 0.328138969
## [194,] -0.2690874942 0.2479465227 -0.161229432 -0.0782074028 0.306830544
## [195,] -0.3307385044 0.0715391768 0.002637362 -0.0673221419 0.398008495
## [196,] -0.3423699384 0.1265831479 -0.098511013 -0.1315320815 0.360138503
## [197,] -0.3681747176 -0.0836059483 0.064177096 -0.0848528161 0.468741292
## [198,] -0.2379207081 0.1266012162 -0.114930701 -0.0907235428 0.423420328
## [199,] -0.3455464242 0.0420689393 -0.087514859 -0.1011320612 0.394455066
## [200,] -0.2147262728 0.0864769238 0.061307880 -0.0952106382 0.285040841
## PC16 PC17 PC18 PC19 PC20
## [1,] -1.2772812638 0.532766557 -0.708636808 -0.3632590994 1.948429e-02
## [2,] 0.2194091263 -0.023834726 -0.154114678 -0.0342256845 -1.357463e-02
## [3,] 0.3382772510 -0.089456675 -0.025632728 0.0410885905 -4.057402e-02
## [4,] 0.1691269289 -0.027656527 -0.026202063 0.0390219973 -6.352123e-02
## [5,] 0.1366006440 -0.038774416 0.083270093 -0.0806204853 3.702010e-01
## [6,] 0.1561911956 0.005056132 -0.012559914 0.0497030919 -6.380402e-02
## [7,] 0.2908514875 -0.029176805 -0.001472707 0.0662343054 -5.391093e-02
## [8,] 0.4493673832 -0.072468185 0.007644938 0.0857034999 -4.197044e-02
## [9,] 0.3170061026 0.041201191 -0.085136208 0.0520133925 -5.514890e-02
## [10,] 0.4259098256 0.020314829 -0.100690425 0.0591889155 -4.859855e-02
## [11,] -0.0997019437 -0.136895213 0.257334255 0.0244169182 8.356508e-04
## [12,] -0.0795459614 -0.175279920 0.252368740 0.0337329436 3.905658e-03
## [13,] -0.1572868121 -0.196788299 0.239717265 0.0383684174 3.032062e-03
## [14,] -0.2629125484 -0.193048424 0.215543349 0.0368770816 -1.619555e-03
## [15,] -0.3697565063 -0.172066550 0.194522608 0.0321248102 -6.075905e-03
## [16,] -0.4303134936 -0.245626464 0.234484333 -0.0576943348 -1.258322e-02
## [17,] -0.4461757876 -0.221562039 0.208445408 -0.0551905207 -9.177834e-03
## [18,] -0.4014752842 -0.219192076 0.185442157 -0.0491518876 -2.986431e-03
## [19,] -0.3186235871 -0.234904409 0.152767805 -0.0350059616 2.216218e-03
## [20,] -0.3284973320 -0.268390730 0.141722601 -0.0259818618 8.061723e-03
## [21,] 0.5264617871 0.383861434 -0.128330125 0.0345479683 6.233090e-03
## [22,] 0.4387855545 0.394119268 -0.159835698 0.0426567682 3.680414e-03
## [23,] 0.3333169478 0.413900947 -0.199032841 0.0423698063 -7.712752e-04
## [24,] 0.2574829484 0.437093134 -0.222129665 0.0410951676 -2.428732e-03
## [25,] 0.2241545052 0.457114580 -0.233827465 0.0492355010 3.085734e-03
## [26,] 0.1096790058 -0.134311302 0.002491709 -0.0516532791 -2.146389e-02
## [27,] 0.1398854448 -0.167177301 -0.001426719 -0.0410799487 -1.236624e-02
## [28,] 0.1634015065 -0.187878654 -0.031571451 -0.0228070045 -7.001647e-03
## [29,] 0.1412991110 -0.212613196 -0.069883575 -0.0145759927 -5.904902e-03
## [30,] 0.1081265978 -0.224903944 -0.116177693 -0.0129515822 -1.019692e-02
## [31,] -0.0246710988 -0.217630818 -0.124080777 -0.0100046983 -1.043410e-02
## [32,] -0.1204909708 -0.188151203 -0.146694858 -0.0015460754 -1.035600e-02
## [33,] -0.1181520995 -0.172845463 -0.190134214 0.0019187633 -8.543466e-03
## [34,] -0.1143458241 -0.169320017 -0.201653637 0.0133100817 -1.584353e-03
## [35,] -0.0810401112 -0.183167566 -0.243584356 0.0242585483 3.403599e-03
## [36,] -0.1079441553 -0.203501064 -0.262493492 0.0375446243 1.235437e-02
## [37,] -0.1359311585 -0.218384745 -0.294258220 0.0489875035 1.658207e-02
## [38,] -0.1795645508 -0.213449761 -0.345413258 0.0693345916 1.435507e-02
## [39,] -0.2920846332 -0.222235687 -0.360757337 0.0752859862 1.587436e-02
## [40,] -0.3467832408 -0.204560358 -0.398420598 0.0897705547 1.530306e-02
## [41,] 0.0841051828 0.239980144 0.272932043 -0.2131929806 -1.132088e-02
## [42,] 0.1547938220 0.216217362 0.292947865 -0.1825520584 -9.037906e-03
## [43,] 0.1972484612 0.208354025 0.277181471 -0.1650541018 -4.641913e-03
## [44,] 0.2236526027 0.203580786 0.256631099 -0.1384523718 1.399432e-04
## [45,] 0.2349111541 0.171017557 0.248824564 -0.1184699410 7.069924e-03
## [46,] 0.2564534104 0.140040283 0.219710320 -0.0966342698 9.443502e-03
## [47,] 0.2693896458 0.118326290 0.190249784 -0.0757658763 1.203310e-02
## [48,] 0.2185525055 0.107284748 0.168863113 -0.0533308238 1.313961e-02
## [49,] 0.1570658279 0.088393522 0.154505529 -0.0401428265 1.545870e-02
## [50,] 0.0866244307 0.079792475 0.132314360 -0.0305885630 1.700973e-02
## [51,] 0.0581132640 0.086250545 0.091573983 -0.0174739099 1.863734e-02
## [52,] 0.0439629268 0.087220424 0.066744335 -0.0020688076 2.308456e-02
## [53,] 0.0310676998 0.084450836 0.032246034 0.0153612308 2.601986e-02
## [54,] 0.0054726056 0.074918992 0.015682581 0.0351069203 3.291798e-02
## [55,] 0.0262317688 0.072726127 -0.027924751 0.0613873154 3.481436e-02
## [56,] 0.0321339703 0.044206897 -0.071274789 0.0639420976 3.928215e-02
## [57,] 0.0232279044 0.040089571 -0.114589008 0.0672838784 4.065168e-02
## [58,] -0.0863960620 0.070315712 -0.099864717 0.0996700408 4.511787e-02
## [59,] -0.1074224887 0.071587127 -0.117538073 0.1178510337 4.797140e-02
## [60,] -0.0798738841 0.030564023 -0.062652821 0.0682346511 -3.822380e-01
## [61,] -0.0781639642 -0.151087245 -0.046189320 -0.0905101269 2.846356e-02
## [62,] 0.1164399959 -0.220347574 -0.106414159 -0.2418818472 1.424725e-02
## [63,] -0.0316734930 -0.005431590 -0.203950365 -0.2349573751 -3.288040e-02
## [64,] -0.5079739617 0.256257190 0.216528843 0.0648666998 -1.534545e-02
## [65,] 0.0723184093 -0.194491071 -0.153090989 -0.0464835711 -4.798724e-03
## [66,] 0.0816331962 -0.019928450 -0.088350039 -0.0417108785 -5.364735e-03
## [67,] 0.1481734037 0.040554802 -0.051210706 -0.0412233228 1.013642e-03
## [68,] 0.1969548458 0.045077937 -0.034426650 -0.0372392387 5.152811e-03
## [69,] 0.1643053129 0.049388318 -0.024192351 -0.0317188399 3.758349e-03
## [70,] 0.0983691485 0.084914204 -0.025343164 -0.0131501547 -4.021765e-03
## [71,] -0.4359311634 0.303597219 0.285291628 0.2104793036 3.703984e-03
## [72,] -0.1516254287 -0.026278328 0.007241481 0.1123516637 2.680873e-03
## [73,] -0.3183139904 0.126560725 0.049811143 0.1099661878 -4.544172e-03
## [74,] -0.3617035184 0.215669899 0.073441824 0.1078633761 -2.334390e-03
## [75,] -0.2728979756 0.240425052 0.076969286 0.1101589579 2.948504e-03
## [76,] -0.1771985157 0.246587343 0.079697084 0.1285910809 9.147525e-03
## [77,] -0.1033066613 0.211063709 0.088129201 0.1372669729 1.473048e-02
## [78,] -0.0843312515 0.197592971 0.074196897 0.1551559265 1.463087e-02
## [79,] -0.1282182970 0.192782469 0.070247722 0.1645425388 1.016649e-02
## [80,] -0.1907488715 0.204329102 0.054871844 0.1615935134 5.481176e-03
## [81,] 0.0281032258 0.095156102 0.310167135 -0.0835789262 -4.395706e-02
## [82,] -0.1009008526 0.111256259 0.230340793 -0.0888361948 -2.984034e-02
## [83,] -0.0205954822 0.031378409 0.183794889 -0.0881391826 -1.908422e-02
## [84,] 0.0200806762 -0.030317454 0.156069859 -0.0688999607 -1.212659e-02
## [85,] 0.0537323764 -0.079817394 0.121710027 -0.0590223316 -9.841380e-03
## [86,] 0.0860153061 -0.121191430 0.080614592 -0.0576947710 -7.948113e-03
## [87,] 0.0693189955 -0.123228826 0.045580413 -0.0541702657 -9.831294e-03
## [88,] 0.0271304722 -0.112066876 0.016523003 -0.0486794081 -1.087365e-02
## [89,] -0.0605520186 -0.096128441 0.019999278 -0.0503929996 -6.846915e-03
## [90,] -0.0635238829 -0.075352528 -0.001799890 -0.0376277623 -7.424317e-03
## [91,] -0.0475349635 -0.077816579 -0.012738973 -0.0259290149 -2.979670e-03
## [92,] -0.0265061883 -0.075543526 -0.010385828 -0.0113968570 4.921011e-03
## [93,] 0.0664378536 -0.095243826 -0.029363357 0.0122486098 7.763743e-03
## [94,] 0.1668948473 -0.142171106 -0.062321745 0.0001622730 1.283190e-02
## [95,] 0.1737587948 -0.146826461 -0.057097588 0.0107999434 1.827583e-02
## [96,] 0.1435432402 -0.136709766 -0.059076841 0.0296314522 1.912140e-02
## [97,] 0.1320653593 -0.141615659 -0.051750437 0.0412257276 2.058596e-02
## [98,] 0.0873852406 -0.122197802 -0.047192806 0.0669188376 1.974552e-02
## [99,] 0.0213908162 -0.088327495 -0.042748929 0.1045563770 2.044353e-02
## [100,] -0.0243900680 -0.073266313 -0.039343641 0.1182108224 2.345780e-02
## [101,] 0.1455586887 -0.040075554 0.086520705 0.1075165319 5.355892e-02
## [102,] -0.0220379367 0.052390884 0.080269889 0.0943858386 3.592751e-02
## [103,] 0.0223319441 -0.013116787 0.014733898 0.0503112292 2.073570e-02
## [104,] -0.0413666760 -0.023805382 0.017464197 0.0655067718 1.355359e-02
## [105,] -0.0786731584 0.072157748 0.010540705 -0.0014755099 7.397580e-04
## [106,] 0.0132038108 0.039140300 -0.023339504 -0.0419932806 -8.902584e-03
## [107,] -0.0311365383 0.044704117 -0.021391303 -0.0500388430 -1.767627e-02
## [108,] 0.0830268515 -0.042888912 -0.038594413 -0.0590054337 -2.378427e-02
## [109,] 0.0624144807 -0.093125384 -0.060849318 -0.0509649050 -3.174816e-02
## [110,] 0.0549282368 -0.006451169 -0.062895986 -0.1203727143 -4.290134e-02
## [111,] -0.3866186784 0.086819018 -0.016977902 -0.0040985861 -6.104936e-04
## [112,] -0.0841254910 -0.014910122 -0.040894768 -0.0146741322 1.343191e-02
## [113,] -0.1631505876 0.093140875 0.127254197 0.0777496381 2.319686e-02
## [114,] 0.2201473712 -0.087591197 0.041652155 0.0507011359 3.964944e-02
## [115,] -0.2904087266 0.204190121 -0.154168957 -0.0385161590 -1.452150e-02
## [116,] -0.1266253285 0.099143081 -0.162318993 -0.0261097918 -4.856295e-03
## [117,] -0.0632701303 0.042279264 -0.169869445 0.0174675931 -1.068331e-03
## [118,] -0.0162709420 0.113904642 -0.140936036 -0.0068140515 2.429531e-03
## [119,] 0.0850252008 0.068690492 -0.118658757 -0.0055756922 8.475327e-03
## [120,] 0.0682870221 0.046778211 -0.103896579 0.0194614529 1.138660e-02
## [121,] 0.0576383697 0.097348754 -0.107050734 -0.0142386208 6.912725e-03
## [122,] 0.0781512016 0.049181896 -0.132518252 -0.0444510369 7.772955e-03
## [123,] -0.0181091785 0.061407405 -0.105373105 -0.0283666302 4.703036e-03
## [124,] 0.0378728898 -0.004174036 -0.150546563 -0.0324325666 9.510440e-05
## [125,] -0.0680145000 -0.005585919 -0.131020594 0.0077646103 -2.241784e-03
## [126,] -0.1443732245 0.098037906 -0.097868710 -0.0210617145 -3.258523e-03
## [127,] -0.0003197474 0.066162609 -0.116055150 -0.0234710446 -3.360502e-03
## [128,] -0.0304243465 0.076596179 -0.073877642 0.0100119713 2.472037e-03
## [129,] 0.0047916340 0.124545243 -0.049287816 -0.0128052340 5.088006e-03
## [130,] 0.1104558891 0.113677348 -0.156065323 -0.0325003088 3.157504e-04
## [131,] 0.1691747435 0.032681593 -0.092535881 -0.0258790137 6.877947e-03
## [132,] 0.2761237350 -0.071260564 -0.148437742 -0.0364377084 5.363830e-03
## [133,] 0.1623310068 -0.084215538 -0.123536793 0.0090780422 1.923555e-03
## [134,] 0.0358790505 0.005407556 -0.091786141 -0.0259167195 -1.868920e-03
## [135,] 0.0763340772 -0.007016453 -0.102978346 -0.0340098096 -1.923455e-03
## [136,] 0.0371652624 0.023029964 -0.096620478 -0.0085758162 -4.198639e-03
## [137,] 0.1810049030 -0.050073940 -0.105824644 0.0155572165 -3.409653e-04
## [138,] 0.1984149196 -0.118648018 -0.088917411 0.0623553744 7.533321e-03
## [139,] 0.1665431830 -0.043443506 -0.067749168 0.0167410746 7.979927e-03
## [140,] 0.1520883226 0.026857558 -0.054894939 -0.0162339993 6.699573e-03
## [141,] 0.1916234058 -0.031077124 -0.094949919 -0.0529035283 3.980255e-03
## [142,] -0.0917172802 0.140895008 0.034544622 0.0239721654 -6.226831e-03
## [143,] 0.0714986691 0.016638424 -0.064957589 -0.0240337694 -5.624573e-03
## [144,] -0.0279190066 0.038235602 -0.012949258 0.0085872841 -4.549613e-03
## [145,] 0.1007956937 -0.028165946 -0.037349214 0.0179964224 -6.331879e-06
## [146,] 0.1139821771 -0.050822320 -0.020720160 0.0772312977 2.569123e-03
## [147,] 0.1269434111 -0.020329174 0.008896105 0.0428865210 7.232259e-03
## [148,] 0.1377544999 0.015133892 0.013263085 0.0036714879 6.885853e-03
## [149,] 0.2066986970 -0.050472006 -0.032259842 -0.0338729918 7.288007e-03
## [150,] -0.0629003465 0.108883244 0.077016706 0.0287707570 -2.184297e-03
## [151,] 0.0848740103 -0.012187883 -0.031066539 -0.0246306349 -2.926253e-03
## [152,] -0.0502346925 0.027909756 0.005443477 0.0012314889 -4.974489e-03
## [153,] 0.0827774578 -0.041278076 -0.032867589 0.0055785840 -3.087443e-03
## [154,] 0.0648748344 -0.052358800 -0.016065032 0.0554149552 -2.086600e-03
## [155,] 0.0424507783 0.009329302 0.016565670 0.0224212528 1.286753e-03
## [156,] 0.1474324246 -0.027459260 0.002793366 0.0146186859 3.537625e-03
## [157,] 0.0921747060 -0.033875703 0.034273835 0.0396726363 5.565344e-03
## [158,] 0.0502955852 0.022910881 0.039043079 0.0068333395 2.280605e-03
## [159,] 0.0592664115 -0.021599977 -0.001942318 -0.0356033514 2.459284e-03
## [160,] -0.0409891234 0.015325804 0.024784387 -0.0197564430 -1.425256e-03
## [161,] 0.0601203014 -0.047127226 -0.047425536 -0.0338495948 -5.475235e-03
## [162,] -0.0527977333 -0.032828966 -0.004186065 0.0091046544 -5.649836e-03
## [163,] -0.0815307997 0.057236271 0.010410473 -0.0167455742 -6.074838e-03
## [164,] -0.0037532049 0.010568926 -0.007833682 -0.0403849447 -1.628959e-03
## [165,] -0.0054667469 0.020474367 0.015899604 -0.0103528159 4.860491e-05
## [166,] 0.1188922894 -0.078806603 -0.012039690 -0.0061854909 2.281355e-03
## [167,] 0.0136101687 -0.102471815 0.027774098 0.0463770490 3.853532e-03
## [168,] -0.0196458314 -0.032448070 0.015463376 0.0071485414 -1.828907e-03
## [169,] -0.0384911966 -0.024847634 0.008032633 0.0003164844 -6.511265e-03
## [170,] -0.1775109377 -0.004433580 0.058418206 0.0331830425 -5.963495e-03
## [171,] -0.2278739298 0.075120499 0.072645139 0.0031527223 -8.009107e-03
## [172,] -0.1365933497 0.043221416 0.046771836 -0.0182466027 -6.334751e-03
## [173,] -0.1661496846 0.072570657 0.078482219 0.0125329350 -4.374282e-03
## [174,] 0.0002405333 -0.010686706 0.030091145 0.0092439357 -4.162287e-03
## [175,] -0.0750237555 -0.036534475 0.086191541 0.0555451285 1.568249e-03
## [176,] -0.0672629749 0.010923597 0.079575254 0.0207698408 -1.918867e-03
## [177,] -0.0072515544 -0.022616268 0.048589736 0.0023494744 -4.730804e-03
## [178,] -0.1398096950 -0.001513531 0.090440576 0.0202394739 -5.814435e-03
## [179,] -0.2095419204 0.068841157 0.119539288 -0.0070592686 -6.772658e-03
## [180,] -0.0861654922 0.019404834 0.047013228 -0.0466230612 -7.433472e-03
## [181,] -0.2434065094 0.144134343 0.153112764 0.0074374029 -9.508835e-03
## [182,] -0.0043312726 0.001478207 0.044266633 -0.0445958597 -4.881454e-03
## [183,] -0.0280244536 0.008563847 0.090179579 -0.0098521800 -1.603812e-04
## [184,] 0.1461135281 -0.127372362 0.039761067 -0.0213720445 6.962917e-04
## [185,] 0.0692215095 -0.127437357 0.046527977 0.0221658116 -1.722449e-03
## [186,] -0.0367456964 -0.037170080 0.070441282 -0.0142204935 -4.628261e-03
## [187,] 0.0074468764 -0.079067586 0.057571276 -0.0337945092 -4.201129e-03
## [188,] -0.0711551481 -0.045593843 0.080640738 -0.0079588734 -5.759127e-03
## [189,] 0.0513924087 -0.132974387 0.049197076 -0.0050273552 -7.462588e-03
## [190,] -0.0945292271 -0.076358550 0.065454966 0.0583214025 7.413986e-03
## [191,] -0.0505567031 -0.054017943 0.104782726 0.0138453274 -2.487277e-03
## [192,] 0.0266203954 -0.072238399 0.086794782 0.0064964565 -4.204574e-03
## [193,] -0.0634724681 -0.059486404 0.116190718 0.0323329333 -3.214718e-03
## [194,] -0.1161910510 -0.002167094 0.144432094 0.0003512244 -3.421256e-03
## [195,] -0.0591186357 -0.053894010 0.104025383 -0.0346310620 -4.312171e-03
## [196,] -0.1265448173 -0.007498196 0.118762077 -0.0138028677 -7.893171e-03
## [197,] -0.0046895007 -0.106484808 0.075486679 -0.0277244271 -8.137764e-03
## [198,] -0.0575542807 -0.097212694 0.109503067 0.0209752463 -6.061269e-03
## [199,] -0.1016308616 -0.029292046 0.149163075 -0.0109118762 -3.867250e-03
## [200,] -0.0245192013 -0.040182370 0.095251599 -0.0267247887 1.239733e-02
## PC21 PC22 PC23 PC24 PC25
## [1,] -2.136951e-02 -0.0068936176 -0.0688776044 -2.400782e-02 0.0084777609
## [2,] 1.628447e-02 0.0322981804 -0.0507824918 7.704971e-02 0.0311038143
## [3,] 2.285523e-02 0.0376522855 -0.0300010555 6.478773e-02 0.0162010168
## [4,] 1.942038e-02 0.0328895200 -0.0114478139 2.900579e-02 -0.0024639423
## [5,] 2.520074e-02 -0.0306720461 0.0346836924 -1.256391e-03 -0.0001832372
## [6,] 7.820286e-03 0.0134788991 -0.0047734239 -9.960963e-03 -0.0142550046
## [7,] 1.144855e-03 0.0034660782 0.0017687945 -2.272042e-02 -0.0152961961
## [8,] -6.901526e-03 -0.0082297778 0.0110613323 -3.647501e-02 -0.0172170994
## [9,] -1.491321e-02 -0.0035590310 0.0444343274 -3.114766e-02 -0.0087808175
## [10,] -2.237756e-02 -0.0107676044 0.0611459083 -4.543936e-02 -0.0096009688
## [11,] 8.039009e-03 0.0147286309 0.0142667996 1.051552e-02 0.0150681111
## [12,] 7.039156e-03 0.0129051814 0.0180042967 7.649078e-03 0.0118266687
## [13,] 6.354487e-03 0.0084052165 0.0212446210 1.738160e-03 0.0037739222
## [14,] 5.980776e-03 0.0051438385 0.0204873301 -4.583319e-03 -0.0031049854
## [15,] 5.365771e-03 0.0021586131 0.0153251478 -7.487156e-03 -0.0059337103
## [16,] 2.461233e-03 -0.0019886065 -0.0234708824 6.063968e-03 -0.0014546981
## [17,] -5.616489e-03 -0.0126838241 -0.0252788109 8.337486e-03 -0.0018485744
## [18,] -1.185542e-02 -0.0213213918 -0.0211609724 5.542599e-03 0.0014548776
## [19,] -2.053146e-02 -0.0311225705 -0.0126377874 1.607554e-04 -0.0021140932
## [20,] -2.497292e-02 -0.0387817936 -0.0079682145 -3.413649e-03 -0.0078475224
## [21,] 6.090713e-03 0.0130309502 0.0145370551 -7.508126e-03 0.0079329376
## [22,] 3.494759e-03 0.0070084880 0.0048604371 -1.557066e-03 0.0031907674
## [23,] -4.856877e-04 -0.0012986420 0.0031318509 -7.487401e-03 -0.0036384865
## [24,] -3.655328e-03 -0.0068590972 -0.0002973266 -1.223919e-02 -0.0045294291
## [25,] -1.004880e-02 -0.0163819318 -0.0136749555 8.770285e-04 -0.0011387976
## [26,] 4.195645e-02 0.0673557858 0.0121555955 9.868241e-03 0.0251665410
## [27,] 3.735301e-02 0.0596860115 0.0159911783 7.809520e-03 0.0257524807
## [28,] 3.144455e-02 0.0500107474 0.0141683591 1.158239e-02 0.0233800688
## [29,] 2.680985e-02 0.0424509537 0.0152158364 8.809110e-03 0.0154151593
## [30,] 2.252254e-02 0.0363515562 0.0212326448 -5.403494e-03 0.0054945527
## [31,] 2.078437e-02 0.0302124178 0.0135493692 -3.274816e-03 0.0014515043
## [32,] 1.711720e-02 0.0214758701 0.0022316951 1.172469e-03 0.0026325073
## [33,] 9.452568e-03 0.0120045724 -0.0084222742 9.224477e-03 0.0030245075
## [34,] 2.186151e-03 0.0018852880 -0.0127340316 1.370351e-02 0.0049497896
## [35,] -8.076000e-03 -0.0131837202 0.0019113942 -2.042002e-03 -0.0014603381
## [36,] -1.594340e-02 -0.0260113003 0.0008336801 2.443261e-03 -0.0060953433
## [37,] -2.140868e-02 -0.0349716957 -0.0028044185 5.360614e-03 -0.0102449574
## [38,] -3.122462e-02 -0.0493444906 0.0052898107 -8.268463e-03 -0.0239951262
## [39,] -3.387168e-02 -0.0568653801 0.0024982088 -1.490175e-02 -0.0296474192
## [40,] -3.880821e-02 -0.0659391016 -0.0101403594 -9.213603e-03 -0.0304552409
## [41,] -4.033747e-03 0.0106023432 -0.0498703937 -4.218557e-02 0.0064609210
## [42,] -1.139886e-02 -0.0053518276 -0.0580780033 -1.003234e-02 0.0015576091
## [43,] -1.410156e-02 -0.0085885360 -0.0507485231 -7.185632e-03 0.0020485974
## [44,] -1.343581e-02 -0.0097978226 -0.0372385498 -9.476444e-03 0.0050593216
## [45,] -1.101142e-02 -0.0086409497 -0.0366413956 -1.216779e-03 0.0080736513
## [46,] -1.154630e-02 -0.0096787435 -0.0200913819 -9.414006e-03 0.0017666181
## [47,] -1.103111e-02 -0.0099322264 -0.0220276839 -2.921070e-03 0.0013844206
## [48,] -8.374558e-03 -0.0086544981 -0.0132468007 -6.620434e-03 -0.0019713959
## [49,] -3.389580e-03 -0.0054354385 -0.0184585339 1.398569e-03 -0.0001419913
## [50,] 1.980470e-04 -0.0034520764 -0.0126738132 7.465153e-04 -0.0010491194
## [51,] 1.352837e-03 -0.0028163622 -0.0070199478 6.296384e-03 -0.0007104104
## [52,] 1.918413e-03 -0.0027549449 -0.0070073697 1.771440e-02 0.0021422424
## [53,] 1.547666e-03 -0.0031684408 0.0147512675 1.019017e-02 -0.0021060342
## [54,] 3.709952e-03 -0.0017378358 0.0197370885 2.193941e-02 0.0001570571
## [55,] 1.778950e-03 -0.0033932946 0.0308977768 2.088290e-02 -0.0032410957
## [56,] 3.599677e-03 -0.0016699225 0.0331215164 3.363814e-02 -0.0025679873
## [57,] 1.897395e-03 -0.0014673146 0.0525401251 3.231199e-02 -0.0088679932
## [58,] 1.617523e-03 -0.0021277885 0.0669906278 3.433061e-02 -0.0123765500
## [59,] 8.654862e-04 -0.0021011006 0.0690044213 3.429918e-02 -0.0125151574
## [60,] 2.272095e-02 0.0038260694 -0.0390812163 -6.274839e-04 0.0002827883
## [61,] 1.343117e-03 0.0145521729 0.0147740196 -4.060737e-02 -0.0029610703
## [62,] 6.735215e-03 0.0492955091 -0.0477223824 -1.829711e-01 0.0289707463
## [63,] 1.784171e-02 0.0288655705 0.0700633455 1.769569e-02 -0.0544261038
## [64,] 1.258953e-02 0.0024898153 -0.0253460362 4.811838e-02 -0.0013547055
## [65,] 3.906557e-02 0.0162757986 -0.0721523232 6.570389e-02 0.0002083976
## [66,] 1.502419e-02 0.0045892500 -0.0159873613 3.562936e-02 -0.0076459098
## [67,] 1.618207e-03 -0.0004813422 0.0150159980 2.854503e-02 -0.0078836992
## [68,] -6.302498e-03 -0.0036249746 0.0380617945 2.099467e-02 -0.0124873566
## [69,] -8.080945e-03 -0.0027564694 0.0576187350 6.388124e-03 -0.0180115283
## [70,] -1.226493e-02 -0.0047437495 0.0641045773 -1.292371e-02 -0.0259590005
## [71,] -5.641451e-03 -0.0115544528 0.0044005885 -1.227567e-02 0.0080664953
## [72,] 1.795030e-02 0.0032433039 -0.0345522566 -4.688382e-03 0.0027318969
## [73,] 6.794672e-03 -0.0016791379 -0.0132493309 -1.835267e-02 -0.0023504826
## [74,] 1.087113e-04 -0.0046326462 -0.0122722602 -1.070402e-02 0.0071059986
## [75,] -8.496419e-03 -0.0094311560 -0.0092142450 -8.635119e-03 0.0136460367
## [76,] -1.551029e-02 -0.0145836380 -0.0022624876 -1.113963e-02 0.0183479352
## [77,] -1.807057e-02 -0.0156273651 0.0015735210 -2.049868e-02 0.0210867430
## [78,] -2.095104e-02 -0.0182132130 0.0026692311 -2.125261e-02 0.0178283770
## [79,] -2.219621e-02 -0.0191027272 0.0011985681 -3.609338e-02 0.0132806740
## [80,] -2.082640e-02 -0.0176523794 -0.0105371959 -3.926602e-02 0.0159115712
## [81,] -2.285059e-02 -0.0366986738 0.0477962294 1.192227e-02 -0.0588140338
## [82,] -2.895144e-03 -0.0086681776 0.0571283997 3.401167e-03 -0.0378104535
## [83,] 3.717333e-03 -0.0004316863 0.0484845155 -1.644224e-03 -0.0266631505
## [84,] 7.701521e-03 0.0017147658 0.0467376493 2.972885e-04 -0.0226231026
## [85,] 9.035807e-03 0.0041327951 0.0422859126 -8.889334e-03 -0.0223246916
## [86,] 1.089303e-02 0.0058640887 0.0236443619 6.323065e-03 -0.0173652300
## [87,] 9.503551e-03 0.0055476991 0.0212036150 6.976922e-04 -0.0181363797
## [88,] 8.524609e-03 0.0059596014 0.0223557640 -1.260320e-03 -0.0189604194
## [89,] 1.208064e-02 0.0106967037 0.0059002219 7.482237e-03 -0.0082419020
## [90,] 8.150705e-03 0.0081981706 0.0033306241 -1.669981e-03 -0.0061760614
## [91,] 6.796187e-03 0.0062877337 -0.0035906679 3.660868e-03 0.0010509731
## [92,] 5.126880e-03 0.0062586554 -0.0213480715 1.562684e-02 0.0123410473
## [93,] 3.188059e-07 0.0006823543 -0.0159888294 1.725056e-03 0.0141883405
## [94,] -4.641047e-04 0.0039704313 -0.0271031130 1.091764e-03 0.0225790778
## [95,] -1.931504e-03 0.0046056438 -0.0401521175 1.373078e-02 0.0291619242
## [96,] -4.636649e-03 0.0027209349 -0.0357908490 7.497775e-03 0.0278617871
## [97,] -7.049548e-03 0.0012281060 -0.0423423763 2.390831e-03 0.0297032940
## [98,] -1.060515e-02 -0.0025358773 -0.0404154906 -6.728492e-03 0.0276719704
## [99,] -1.280547e-02 -0.0070244772 -0.0434603435 -4.771902e-03 0.0292378351
## [100,] -1.067062e-02 -0.0042532499 -0.0612236570 -6.060895e-03 0.0406050662
## [101,] 5.871410e-02 0.0980037156 -0.0924839201 -1.299026e-02 -0.0526930786
## [102,] 5.199860e-02 0.0832665982 -0.0720009354 6.577693e-03 -0.0381908724
## [103,] 3.449179e-02 0.0621740950 -0.0264135171 -2.468376e-02 -0.0289626130
## [104,] 3.123992e-02 0.0412718069 -0.0299680091 -1.586125e-02 -0.0178623610
## [105,] 1.313329e-02 0.0230875535 -0.0006669042 1.416928e-02 -0.0033174386
## [106,] -1.003644e-02 -0.0084404947 0.0181625410 1.235311e-02 0.0096775240
## [107,] -2.023191e-02 -0.0311791849 0.0312246451 1.589022e-02 0.0170854159
## [108,] -4.606003e-02 -0.0698007730 0.0431337940 -3.024473e-03 0.0283442971
## [109,] -4.529449e-02 -0.0867042989 0.0544460679 -1.152157e-02 0.0362750511
## [110,] -6.919936e-02 -0.1134659003 0.0756881182 1.929436e-02 0.0498101462
## [111,] 3.428151e-02 0.0561675621 -0.0443285026 9.610972e-03 -0.0233689433
## [112,] 2.708039e-02 0.0491517608 -0.0439397383 1.596932e-02 -0.0176241827
## [113,] 2.418284e-02 0.0416436314 -0.0164841896 -1.844071e-02 -0.0204916297
## [114,] 2.385431e-02 0.0400135129 -0.0347074542 3.237217e-03 -0.0078275121
## [115,] 2.354129e-02 0.0719686571 0.0414768797 7.583747e-03 0.0046940504
## [116,] 2.023171e-02 0.0667758499 0.0372944250 -4.032290e-04 0.0150830768
## [117,] 2.742434e-02 0.0641003593 0.0357688135 -2.057305e-02 0.0092286181
## [118,] 1.361431e-02 0.0528567053 0.0294008915 1.066259e-02 0.0132526542
## [119,] 1.024406e-03 0.0400059153 0.0283692750 2.220299e-03 0.0136267168
## [120,] 8.942614e-03 0.0433531558 0.0234663061 -6.330352e-03 0.0122390612
## [121,] 1.392268e-03 0.0413488948 0.0347730784 -5.080127e-03 0.0062479052
## [122,] 4.607955e-03 0.0476484815 0.0278783929 4.620784e-03 0.0119847823
## [123,] 7.320767e-03 0.0432693017 0.0170169223 -2.559166e-03 0.0068384371
## [124,] 4.123145e-03 0.0403539535 0.0246868985 -2.391991e-02 0.0022625726
## [125,] 1.452509e-02 0.0397578459 0.0129760713 -3.173122e-02 -0.0024863947
## [126,] 1.095313e-02 0.0401780795 0.0085968915 9.055095e-03 0.0050123559
## [127,] -7.513235e-03 0.0188212479 0.0089342193 1.024450e-03 -0.0002945833
## [128,] -8.268170e-04 0.0203225372 -0.0001695205 1.128591e-02 0.0042345498
## [129,] -1.182395e-02 0.0118834766 0.0005432153 2.781922e-02 0.0050342340
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## [177,] 8.188224e-03 -0.0023214206 0.0285593862 -2.041736e-02 0.0031334522
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## [181,] 6.649690e-03 -0.0073240890 0.0219099843 1.305143e-02 0.0052447346
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## [186,] 1.299571e-02 -0.0089329829 0.0061006537 7.592584e-03 0.0047992035
## [187,] 5.952533e-03 -0.0172370767 -0.0056483337 1.299159e-02 0.0055985440
## [188,] 9.444198e-03 -0.0183328036 -0.0126692781 1.654848e-02 0.0018020193
## [189,] 2.317311e-03 -0.0251598807 0.0135597767 -2.777334e-02 -0.0054017680
## [190,] -1.198358e-01 0.0768290820 0.0102679927 -2.468332e-02 -0.0035677951
## [191,] 1.583681e-02 -0.0148119655 0.0003740993 7.635402e-03 0.0071944342
## [192,] 1.078399e-02 -0.0152777436 0.0236493102 -1.415158e-02 0.0062563347
## [193,] 2.297262e-02 -0.0071876811 0.0212155078 -1.789118e-02 0.0081725705
## [194,] 1.557397e-02 -0.0124391777 0.0069847624 1.232557e-02 0.0094152145
## [195,] 1.451170e-02 -0.0107227179 0.0083160536 1.627699e-02 0.0095516985
## [196,] 1.815942e-02 -0.0101445142 0.0073678484 1.581965e-02 0.0078201713
## [197,] 1.100010e-02 -0.0175955879 0.0163026514 -7.273657e-03 0.0010632745
## [198,] 1.585465e-02 -0.0234325152 -0.0030885602 -6.531300e-03 0.0003235432
## [199,] 1.273190e-02 -0.0228702511 -0.0034451579 2.237816e-02 0.0071710555
## [200,] -2.073913e-01 0.1078276463 0.0080832597 3.350389e-02 0.0030462272
## PC26 PC27 PC28 PC29 PC30
## [1,] 1.400450e-03 7.490022e-04 -6.027328e-03 6.365462e-04 -3.136025e-05
## [2,] 1.498605e-04 3.049710e-03 3.546448e-03 -7.377730e-04 5.508214e-05
## [3,] 1.588253e-04 1.810407e-03 3.082577e-03 -7.592008e-04 4.262744e-07
## [4,] -2.881811e-04 7.449734e-04 4.571472e-04 -7.506397e-04 -5.122544e-05
## [5,] 8.961038e-05 1.577647e-05 -8.376816e-07 -1.000396e-07 -4.319691e-09
## [6,] -3.862558e-03 4.808769e-04 -1.046808e-03 -4.996198e-04 -4.596307e-05
## [7,] -4.591528e-03 -1.406350e-04 -7.567600e-04 -2.121641e-04 -8.325860e-05
## [8,] -5.049167e-03 -1.025039e-03 -4.626144e-04 3.737173e-05 6.737717e-05
## [9,] -1.125186e-03 -2.421926e-03 3.977170e-04 8.190088e-04 5.600030e-05
## [10,] -1.195946e-05 -3.769853e-03 7.375902e-04 1.175233e-03 2.318850e-05
## [11,] 1.637993e-03 2.329285e-03 -2.127766e-03 -2.498855e-03 -1.532799e-04
## [12,] 1.943439e-02 7.845435e-04 -1.631073e-03 -1.783291e-03 -9.449859e-05
## [13,] 3.768485e-03 -9.206747e-04 -2.295725e-03 -1.206777e-03 -8.471845e-05
## [14,] -3.983782e-03 -2.128923e-03 -2.733890e-03 -6.014110e-04 -8.502628e-05
## [15,] -1.268248e-02 -2.419605e-03 -2.803555e-03 -1.790702e-04 -5.328785e-06
## [16,] -6.333311e-03 3.115319e-04 4.758121e-04 6.665656e-04 1.285155e-05
## [17,] 8.758836e-03 3.418708e-04 1.051484e-03 9.330438e-04 3.601507e-05
## [18,] -2.446763e-02 -2.327523e-04 1.681553e-03 1.103559e-03 8.186883e-05
## [19,] 9.230285e-03 -1.607619e-03 2.672070e-03 1.608196e-03 1.175364e-04
## [20,] 1.809023e-02 -3.063722e-03 2.669939e-03 1.850150e-03 1.539271e-04
## [21,] -1.220761e-02 3.619864e-03 9.876556e-05 -7.006806e-04 3.326318e-05
## [22,] 1.225443e-02 2.194178e-03 7.175413e-04 2.427378e-05 4.899821e-05
## [23,] -4.460320e-03 6.843156e-04 2.361122e-04 3.270445e-04 -1.327097e-05
## [24,] -1.338561e-02 1.217239e-05 3.700400e-04 3.317059e-04 -1.718364e-05
## [25,] 1.740894e-02 4.718563e-04 1.696038e-03 4.299180e-04 -2.140869e-05
## [26,] -2.714720e-03 7.502320e-03 -4.146281e-03 5.372811e-04 7.696338e-05
## [27,] -1.906064e-02 6.373522e-03 -3.761042e-03 2.833025e-04 6.916217e-05
## [28,] -1.053897e-02 4.815769e-03 -2.676900e-03 6.431732e-04 9.310067e-05
## [29,] 1.513598e-02 2.808945e-03 -2.247434e-03 9.653660e-04 1.805761e-05
## [30,] 2.488345e-02 6.124945e-04 -2.268737e-03 1.134606e-03 3.432681e-05
## [31,] 1.555043e-02 1.146481e-04 -2.300151e-03 8.790974e-04 -4.479600e-05
## [32,] -1.895445e-02 1.320059e-04 -1.600514e-03 6.975285e-04 -1.787682e-05
## [33,] 2.109296e-02 3.233238e-04 1.503184e-04 7.576733e-04 -1.831997e-05
## [34,] 2.804280e-02 4.977578e-04 1.432603e-03 3.169362e-04 -1.005468e-04
## [35,] -2.074055e-02 -1.209620e-03 1.202374e-03 -2.522672e-04 -5.135642e-05
## [36,] -1.314225e-02 -2.007810e-03 1.844889e-03 -6.658464e-04 -2.147518e-05
## [37,] -4.861626e-03 -3.093161e-03 2.963999e-03 -7.931750e-04 -7.697119e-05
## [38,] 1.233083e-02 -5.032467e-03 3.252374e-03 -9.332699e-04 -2.334459e-05
## [39,] -1.258601e-02 -5.717904e-03 3.214675e-03 -1.687401e-03 9.413863e-06
## [40,] -1.354317e-02 -5.635849e-03 4.894692e-03 -1.921281e-03 5.363537e-05
## [41,] 4.134492e-03 -7.967044e-03 -4.869469e-04 -2.619745e-03 3.296582e-04
## [42,] 9.212521e-03 -4.996742e-03 4.103885e-04 -1.076211e-03 2.712932e-05
## [43,] 2.546049e-02 -4.421155e-03 6.140017e-04 -7.062614e-04 -2.273303e-05
## [44,] -2.348818e-02 -4.757479e-03 4.302472e-04 -5.396214e-04 4.728321e-06
## [45,] -2.323484e-02 -4.364919e-03 6.484392e-04 -2.507063e-04 9.389294e-06
## [46,] -5.245914e-03 -5.181026e-03 4.962401e-05 2.255230e-05 -6.206074e-05
## [47,] 2.012399e-02 -4.842110e-03 6.145294e-04 6.414782e-04 -4.224082e-05
## [48,] 2.082198e-02 -4.971074e-03 8.757159e-05 8.136045e-04 -9.745585e-05
## [49,] 1.251237e-02 -3.909819e-03 -3.781791e-05 9.665789e-04 -6.899805e-05
## [50,] -1.204244e-02 -3.214565e-03 -8.996725e-04 8.060501e-04 -1.227767e-04
## [51,] -1.227921e-02 -2.349601e-03 -9.162912e-04 8.879598e-04 -8.087266e-05
## [52,] -4.829682e-03 -7.330234e-04 -5.166878e-04 9.098730e-04 -4.516797e-05
## [53,] -1.246027e-02 -5.411206e-04 -1.382168e-03 5.694128e-04 -9.164629e-06
## [54,] -1.310796e-02 8.238098e-04 -1.209790e-03 3.835370e-04 -6.124455e-05
## [55,] 1.223527e-02 1.474588e-03 -8.848446e-04 5.319178e-04 -1.738136e-05
## [56,] -3.949781e-03 2.759610e-03 -8.676371e-04 5.364184e-04 4.155476e-05
## [57,] -3.552474e-03 3.312546e-03 -1.507650e-03 2.535296e-04 1.000035e-04
## [58,] 3.117207e-03 4.950684e-03 -1.981453e-03 -4.145750e-04 6.312318e-05
## [59,] 1.115139e-02 6.985750e-03 -1.674958e-03 -6.690180e-04 1.104513e-04
## [60,] 1.329956e-04 -1.872702e-05 8.922747e-07 2.058999e-07 5.817884e-09
## [61,] 3.239160e-04 1.450544e-02 3.615865e-03 -6.018304e-04 4.312375e-05
## [62,] -3.291133e-03 1.750730e-02 5.937414e-03 -4.523313e-04 -9.907165e-05
## [63,] -6.456316e-04 -5.799775e-03 -3.026439e-03 -1.315671e-03 5.163891e-05
## [64,] 1.935980e-03 5.033176e-03 2.689362e-03 -1.958213e-03 -5.208123e-05
## [65,] -1.911138e-02 2.689913e-03 1.670694e-03 9.058134e-05 2.589818e-05
## [66,] 9.672024e-03 2.163813e-03 1.050984e-03 -8.875666e-04 -6.377948e-06
## [67,] 1.608108e-02 1.394903e-03 1.072985e-03 -1.163120e-03 -1.060931e-04
## [68,] 1.625130e-02 -2.745737e-04 5.182184e-04 -1.056663e-03 -1.542041e-06
## [69,] -2.398519e-02 -2.447996e-03 -7.453796e-04 -8.785324e-04 -4.654556e-05
## [70,] 1.417752e-03 -3.852925e-03 -1.184667e-03 -2.637775e-04 -1.005336e-05
## [71,] 1.405657e-03 1.821211e-03 2.173086e-03 -6.858321e-04 8.085093e-05
## [72,] -1.384905e-02 -4.779800e-04 1.734182e-04 1.028927e-03 6.725179e-05
## [73,] 6.564645e-03 2.096455e-04 -8.242776e-04 4.268378e-04 6.025363e-05
## [74,] -1.360974e-02 1.793262e-03 -4.023916e-04 1.965529e-04 -2.706232e-05
## [75,] 1.388561e-03 2.664282e-03 2.887501e-04 2.560961e-04 5.160338e-05
## [76,] 9.309469e-04 2.526960e-03 8.021943e-04 5.114468e-04 -2.694242e-05
## [77,] -1.442579e-02 1.914216e-03 6.106821e-04 7.135171e-04 -2.554404e-05
## [78,] 1.087759e-02 8.552182e-04 6.513781e-04 1.434458e-03 -5.606034e-06
## [79,] 2.007311e-02 9.613813e-05 -9.036204e-05 1.890183e-03 -2.929072e-06
## [80,] -4.655320e-03 2.744084e-04 -4.359044e-04 2.371239e-03 2.194832e-05
## [81,] -2.088168e-02 7.744618e-03 6.004684e-04 5.336735e-04 3.024811e-05
## [82,] 1.546802e-02 5.107468e-03 1.444513e-03 1.319797e-04 2.022689e-05
## [83,] 1.025968e-02 3.837727e-03 1.638824e-03 1.448002e-04 -6.182157e-05
## [84,] -2.106853e-02 2.154616e-03 1.044011e-03 1.701292e-04 -6.545902e-06
## [85,] -2.342564e-03 5.828970e-04 6.992993e-04 3.615163e-04 1.817107e-05
## [86,] -1.887137e-03 8.271825e-05 1.002142e-03 8.584335e-04 -1.374842e-05
## [87,] -1.336309e-03 -9.764062e-04 3.153465e-04 9.058705e-04 3.130218e-05
## [88,] 1.496905e-02 -1.872142e-03 -4.355408e-04 7.623869e-04 -1.172945e-05
## [89,] -2.960382e-03 -1.184845e-03 -5.726613e-04 3.532000e-04 1.230587e-05
## [90,] 1.320747e-02 -1.443569e-03 -8.582572e-04 1.971074e-04 -4.951234e-05
## [91,] -1.252628e-02 -1.292503e-03 -1.151564e-03 -1.096366e-04 -1.235928e-05
## [92,] 1.912638e-02 -4.072785e-04 -1.428656e-04 -1.872382e-04 -1.110790e-05
## [93,] -1.295850e-02 -1.509516e-03 -7.404293e-04 -3.564610e-04 -5.415774e-05
## [94,] -1.978284e-02 -1.952897e-03 -4.039303e-04 -2.419563e-04 -4.066721e-05
## [95,] 3.934460e-03 -1.858919e-03 2.279969e-04 -1.718781e-04 -2.822572e-05
## [96,] 3.776012e-03 -3.003126e-03 -5.165747e-04 -3.620870e-04 6.691644e-06
## [97,] 3.410598e-03 -3.243331e-03 -1.010063e-03 -5.618808e-04 3.575511e-05
## [98,] 1.102102e-02 -3.947857e-03 -1.841109e-03 -8.188112e-04 -1.862162e-05
## [99,] 9.384508e-03 -4.270220e-03 -2.273165e-03 -1.021793e-03 3.662486e-05
## [100,] -7.814576e-03 -3.696151e-03 -2.016220e-03 -1.249097e-03 6.853324e-05
## [101,] -2.647838e-02 -6.418643e-04 2.951150e-04 2.682706e-04 8.792043e-06
## [102,] 4.752992e-03 3.636464e-04 8.622057e-04 8.907138e-05 1.727191e-05
## [103,] -1.260597e-02 -1.546329e-03 -1.164416e-03 -1.809547e-04 1.133859e-05
## [104,] 2.781782e-02 -6.911577e-04 -8.943741e-05 -5.280568e-05 5.211382e-06
## [105,] 2.503727e-02 -1.733780e-04 8.003829e-04 -1.172693e-06 9.318078e-06
## [106,] -2.213499e-02 -7.222686e-05 3.637922e-04 6.710023e-05 -4.525036e-05
## [107,] 1.849882e-02 3.928121e-04 5.664202e-04 -1.234977e-05 -6.060521e-05
## [108,] -2.174239e-03 7.898957e-04 -5.956948e-04 1.501920e-05 -2.780397e-05
## [109,] 7.722572e-03 2.302172e-04 -8.556339e-04 -1.001554e-04 6.969367e-05
## [110,] -2.042298e-02 1.348593e-03 -1.826348e-04 -9.203048e-05 1.203385e-05
## [111,] 1.795404e-04 -6.784055e-05 -8.338870e-04 5.938854e-04 -1.074128e-05
## [112,] 1.483578e-03 -3.216769e-04 7.667223e-05 7.519079e-04 -4.269055e-05
## [113,] 4.783452e-03 -2.270191e-04 7.957971e-05 -8.480038e-04 -2.532729e-05
## [114,] 8.396669e-05 -5.274283e-04 1.445830e-03 -4.270099e-05 7.142288e-05
## [115,] 1.153239e-02 -3.063378e-03 1.397436e-03 4.217369e-04 -3.424884e-05
## [116,] -1.766337e-02 -3.184364e-03 1.142725e-03 4.061243e-04 3.504209e-05
## [117,] 9.911742e-05 -4.119010e-03 9.639717e-04 2.991731e-04 -2.891577e-06
## [118,] -1.288469e-02 -2.414470e-03 2.133967e-03 4.312028e-04 -9.282137e-06
## [119,] -1.165003e-02 -2.185665e-03 1.782692e-03 3.122176e-04 -4.767022e-05
## [120,] 5.354183e-03 -2.772835e-03 1.999874e-03 3.367458e-04 -6.083327e-06
## [121,] 1.271020e-02 -3.355094e-03 2.076092e-03 3.878234e-04 3.435490e-05
## [122,] 6.566033e-03 -3.578593e-03 2.004356e-03 7.128422e-04 -9.378522e-05
## [123,] -1.936095e-02 -3.005794e-03 1.351130e-03 4.664484e-04 -4.375568e-05
## [124,] 1.355555e-03 -4.039908e-03 -4.477257e-05 5.591629e-04 2.574967e-06
## [125,] 8.194402e-05 -3.509264e-03 -6.067137e-04 2.112200e-04 -4.357156e-05
## [126,] -1.373065e-02 -1.340393e-03 4.359297e-04 1.558461e-05 -7.724717e-07
## [127,] -2.144144e-02 -6.519735e-04 -3.509661e-04 6.757884e-05 -2.106476e-05
## [128,] 1.004102e-03 2.511890e-04 6.451267e-04 -2.262265e-04 9.772005e-06
## [129,] -1.026486e-02 1.222654e-03 1.091434e-03 -2.482897e-04 -1.640900e-05
## [130,] 3.235556e-04 3.773372e-05 1.321861e-04 7.917166e-05 4.583984e-06
## [131,] 1.740691e-02 4.976753e-04 7.881066e-04 4.764429e-04 1.830677e-05
## [132,] -1.023445e-02 -7.023956e-04 -2.764725e-04 8.336457e-04 8.519710e-05
## [133,] -2.567614e-03 -2.287717e-04 -1.263997e-03 7.981178e-04 4.981241e-05
## [134,] 2.577183e-02 1.352152e-03 -5.677935e-04 5.611178e-04 5.257923e-05
## [135,] 2.595462e-02 2.227591e-03 -5.602630e-04 6.356544e-04 6.954062e-06
## [136,] -7.232874e-03 1.278262e-03 -1.020462e-03 9.361267e-05 5.488716e-05
## [137,] -1.116307e-02 3.971383e-04 -1.708058e-03 -1.242552e-04 7.191011e-06
## [138,] 1.318473e-02 1.207495e-03 -1.370708e-03 5.792194e-06 5.937740e-05
## [139,] -2.224190e-02 1.022902e-03 -4.308488e-04 -2.330295e-04 1.199836e-05
## [140,] 6.942619e-03 2.476176e-03 9.692578e-04 3.707431e-04 -1.948015e-05
## [141,] 1.425828e-03 1.706716e-03 9.178529e-05 5.651531e-04 3.186131e-05
## [142,] -3.170306e-03 2.083642e-03 -1.090651e-03 -4.364219e-04 -2.467612e-05
## [143,] 8.286854e-03 2.392989e-03 -1.172286e-03 3.814401e-04 3.991252e-05
## [144,] -1.986180e-03 3.068870e-03 -1.902402e-03 -3.190324e-04 -2.424670e-05
## [145,] 9.643566e-03 2.519395e-03 -1.832063e-03 -2.568382e-04 -5.723286e-05
## [146,] 1.961244e-03 1.834633e-03 -1.902664e-03 -4.585912e-04 8.673214e-06
## [147,] 6.884935e-03 3.195820e-03 -9.113314e-04 -3.996105e-04 -3.356182e-05
## [148,] 4.731981e-03 3.784772e-03 -4.945855e-04 -9.870964e-05 3.084186e-05
## [149,] -1.764876e-02 3.487855e-03 -4.898597e-04 3.729288e-04 1.249405e-05
## [150,] -2.054919e-02 2.736959e-03 -1.415631e-03 -5.929532e-04 -5.597245e-05
## [151,] 8.313732e-03 2.298907e-03 -1.289268e-03 2.479663e-04 -9.433919e-06
## [152,] 7.068065e-03 1.972470e-03 -1.642767e-03 -4.385938e-04 1.518228e-05
## [153,] 1.027068e-02 1.875305e-03 -1.780722e-03 -1.380914e-04 -1.161270e-05
## [154,] 1.053007e-02 1.242345e-03 -2.070377e-03 -5.086790e-04 -5.390119e-05
## [155,] -1.736574e-02 1.998996e-03 -1.010403e-03 -8.117039e-04 -1.788133e-05
## [156,] 9.227272e-03 1.848457e-03 -8.982791e-04 -3.869977e-04 -5.124561e-05
## [157,] -1.620862e-02 2.220755e-03 -8.314350e-04 -4.784457e-04 -1.296536e-06
## [158,] 6.605624e-03 2.372505e-03 -1.634606e-04 -3.568675e-04 -5.583916e-05
## [159,] -7.434086e-03 1.696075e-03 6.378879e-05 -1.554852e-04 -1.932679e-05
## [160,] -8.741891e-03 1.786744e-03 -2.970807e-04 -4.654002e-04 2.894614e-05
## [161,] -3.934575e-03 7.553278e-05 -7.880073e-04 -1.689723e-04 -1.199405e-05
## [162,] -1.318373e-02 1.837263e-04 -1.507425e-03 -7.624350e-04 1.967696e-05
## [163,] -5.472675e-04 1.219139e-03 2.476555e-04 -7.502414e-04 5.796894e-05
## [164,] 9.817101e-03 7.062356e-04 5.969215e-04 -8.781774e-04 -8.127969e-06
## [165,] -2.410143e-02 1.050955e-03 7.566466e-04 -8.462883e-04 7.514692e-05
## [166,] 3.059308e-02 -3.092259e-04 -1.370471e-04 -6.678617e-04 1.256756e-05
## [167,] -1.021946e-02 -6.252341e-04 -6.170493e-04 -9.879450e-04 -1.761506e-05
## [168,] 2.898890e-02 -7.729663e-04 5.239276e-05 -6.605204e-04 2.869464e-05
## [169,] -1.763992e-03 -1.933907e-03 -5.100627e-04 -8.246809e-04 -3.738006e-06
## [170,] 1.236674e-02 -8.139241e-04 -5.661256e-04 -1.134655e-03 2.521961e-05
## [171,] 1.718694e-02 -3.024383e-06 1.936276e-04 -1.190503e-03 -1.204121e-05
## [172,] 1.004646e-02 -2.643454e-05 4.196419e-04 -1.097876e-03 5.132329e-05
## [173,] 8.394212e-03 3.069440e-04 1.076379e-03 -1.216916e-03 2.750948e-05
## [174,] 1.351655e-02 -1.573134e-03 2.339231e-04 -9.683640e-04 4.374789e-06
## [175,] 1.213253e-02 -5.722498e-04 1.271733e-04 -1.061093e-03 8.041901e-05
## [176,] -2.261565e-02 -5.777964e-04 4.226899e-04 -8.105409e-04 8.197443e-05
## [177,] 1.229351e-02 -1.141708e-03 1.518653e-04 -3.908686e-04 6.365336e-05
## [178,] -2.243615e-02 -6.580088e-04 -4.807110e-04 -5.882882e-04 -3.701991e-05
## [179,] -1.068682e-02 1.280776e-03 4.866657e-04 -4.530270e-04 -5.351819e-05
## [180,] 1.580323e-02 8.111983e-04 1.081860e-03 1.245630e-04 -6.721081e-05
## [181,] 3.406311e-03 1.315806e-03 7.062351e-04 -7.289147e-04 -1.083326e-05
## [182,] 1.647598e-02 2.784140e-04 9.120600e-04 2.842089e-05 6.762565e-05
## [183,] 2.211667e-02 1.700012e-03 1.856467e-03 2.260306e-04 -2.717547e-05
## [184,] -4.699980e-03 -4.803978e-05 -5.015517e-04 4.269156e-04 -2.133036e-05
## [185,] 4.310679e-03 -1.314971e-03 -3.998842e-04 5.233059e-04 -3.609443e-05
## [186,] -7.267159e-03 -8.345648e-04 7.325951e-04 5.037283e-04 1.812348e-05
## [187,] -2.302631e-02 -1.670670e-04 2.172520e-04 8.309028e-04 1.868616e-05
## [188,] 2.428848e-02 3.636690e-04 7.527820e-04 8.902491e-04 -1.902044e-05
## [189,] 1.337828e-02 -1.641883e-03 -1.536572e-03 5.597363e-04 -4.056520e-05
## [190,] 7.184638e-03 -3.449584e-04 -9.903914e-04 -5.872415e-04 -3.416442e-05
## [191,] -1.598808e-05 -4.096257e-04 7.820825e-04 6.165934e-04 1.404938e-05
## [192,] -1.332457e-02 -2.206605e-03 1.283635e-04 5.905053e-04 5.221709e-06
## [193,] -2.216379e-02 -2.630119e-03 4.051444e-04 5.250787e-04 -1.849718e-05
## [194,] -1.791828e-02 -1.034066e-03 1.284431e-03 7.952629e-04 -2.993541e-05
## [195,] -1.578168e-02 -1.706317e-03 8.809186e-04 1.078590e-03 -4.183324e-05
## [196,] -9.165868e-03 -1.665134e-03 1.285433e-03 1.214676e-03 3.203651e-05
## [197,] 1.175537e-02 -2.784033e-03 -3.090743e-04 1.275350e-03 1.049806e-05
## [198,] 1.775643e-02 -1.815387e-03 3.198055e-04 1.398999e-03 8.812983e-06
## [199,] -2.750274e-02 -6.304276e-04 9.278885e-04 1.271642e-03 -8.042398e-05
## [200,] -7.583857e-03 3.088056e-04 8.582182e-04 5.080593e-04 2.958143e-05
## PC31 PC32 PC33 PC34
## [1,] -1.993650e-06 -6.784020e-16 -2.581006e-16 -1.219739e-16
## [2,] 6.345898e-06 -1.226814e-17 -2.581006e-16 -1.095157e-17
## [3,] 2.857439e-06 2.097765e-16 -2.581006e-16 -1.095157e-17
## [4,] -1.880435e-06 -1.226814e-17 -2.581006e-16 -1.095157e-17
## [5,] 1.791243e-08 -2.343127e-16 -2.581006e-16 -1.095157e-17
## [6,] -3.836957e-06 2.097765e-16 -2.581006e-16 -1.095157e-17
## [7,] -4.248764e-06 -1.226814e-17 -2.581006e-16 -1.095157e-17
## [8,] -1.815340e-06 -1.226814e-17 -2.581006e-16 -1.095157e-17
## [9,] 9.075181e-07 4.318211e-16 -2.581006e-16 -1.095157e-17
## [10,] 5.444819e-07 4.318211e-16 -2.581006e-16 -1.095157e-17
## [11,] -5.099401e-06 1.923183e-16 -2.349321e-16 -3.933604e-18
## [12,] -4.683009e-06 1.924337e-16 -2.345982e-16 -3.862188e-18
## [13,] -4.521294e-06 1.810007e-16 -2.338468e-16 -3.604036e-18
## [14,] -4.649053e-06 -4.387094e-17 -2.337471e-16 -3.558880e-18
## [15,] -2.843221e-06 -4.670381e-17 -2.336480e-16 -3.513776e-18
## [16,] 2.144732e-06 1.782765e-16 -2.337570e-16 -3.561873e-18
## [17,] 2.968132e-06 1.840962e-16 -2.339712e-16 -3.656789e-18
## [18,] 6.371232e-06 1.783209e-16 -2.341062e-16 -3.637945e-18
## [19,] 5.932704e-06 1.956194e-16 -2.350762e-16 -3.992344e-18
## [20,] 5.641976e-06 1.871460e-16 -2.340911e-16 -3.708212e-18
## [21,] 9.211416e-07 1.698806e-16 -2.334693e-16 -3.429554e-18
## [22,] 6.901518e-07 1.843064e-16 -2.343352e-16 -3.737465e-18
## [23,] -8.086181e-08 -3.775084e-17 -2.346790e-16 -3.811875e-18
## [24,] 8.208901e-08 1.814609e-16 -2.345798e-16 -3.766770e-18
## [25,] 2.265927e-07 -3.469422e-17 -2.344557e-16 -3.788940e-18
## [26,] 1.904989e-06 1.873436e-16 -2.347990e-16 -3.863297e-18
## [27,] 2.394076e-06 3.922623e-16 -2.335006e-16 -3.439145e-18
## [28,] 3.051264e-06 1.788577e-16 -2.341577e-16 -3.653576e-18
## [29,] 2.748282e-07 1.875674e-16 -2.344765e-16 -3.795259e-18
## [30,] -1.154686e-06 1.962246e-16 -2.351342e-16 -4.009969e-18
## [31,] -2.483867e-06 1.819714e-16 -2.339399e-16 -3.632304e-18
## [32,] 4.331388e-08 1.761961e-16 -2.340749e-16 -3.613460e-18
## [33,] -1.680578e-07 1.963786e-16 -2.351500e-16 -4.014678e-18
## [34,] -1.013994e-06 1.936214e-16 -2.347121e-16 -1.149191e-16
## [35,] 7.800327e-07 1.820835e-16 -2.346385e-16 -1.148070e-16
## [36,] 8.634789e-07 -4.843443e-17 -2.336534e-16 -1.145228e-16
## [37,] -8.084227e-08 -4.550467e-17 -2.337630e-16 -1.145710e-16
## [38,] -1.854850e-06 1.937974e-16 -2.350729e-16 -1.149988e-16
## [39,] -1.966026e-06 1.737815e-16 -2.336699e-16 -1.145278e-16
## [40,] -5.897036e-07 1.852590e-16 -2.347705e-16 -1.148621e-16
## [41,] 1.750362e-06 8.457862e-16 -2.338900e-16 -3.602165e-18
## [42,] 1.171918e-06 4.046441e-16 -2.340001e-16 -3.650595e-18
## [43,] 3.099052e-07 4.104812e-16 -2.342149e-16 -3.745792e-18
## [44,] 2.873524e-06 1.826088e-16 -2.346889e-16 -3.799974e-18
## [45,] 3.332087e-06 3.990003e-16 -2.341468e-16 -3.635356e-18
## [46,] -1.098072e-07 4.048201e-16 -2.343609e-16 -3.730273e-18
## [47,] -4.164495e-07 4.192573e-16 -2.352279e-16 -4.038517e-18
## [48,] -2.770401e-06 4.193085e-16 -2.352339e-16 -4.040232e-18
## [49,] -2.015141e-06 4.107654e-16 -2.345871e-16 -3.828848e-18
## [50,] -2.705592e-06 1.744324e-16 -2.337323e-16 -3.524489e-18
## [51,] -1.670373e-06 4.022385e-16 -2.342858e-16 -3.692485e-18
## [52,] -3.946222e-07 4.051855e-16 -2.343960e-16 -3.740915e-18
## [53,] -8.457979e-07 -4.171925e-17 -2.342974e-16 -3.696091e-18
## [54,] -1.065951e-06 -4.737822e-17 -2.337558e-16 -3.531526e-18
## [55,] -1.804185e-06 -2.724813e-17 -2.351697e-16 -4.005770e-18
## [56,] 1.582002e-06 1.891082e-16 -2.349672e-16 -3.914459e-18
## [57,] 2.960260e-06 1.891595e-16 -2.349731e-16 -3.916175e-18
## [58,] 1.116930e-06 -4.135845e-17 -2.339881e-16 -3.632043e-18
## [59,] 1.516604e-06 -3.841727e-17 -2.340987e-16 -3.680526e-18
## [60,] -2.403936e-08 -2.604572e-16 -2.344430e-16 -3.755215e-18
## [61,] 2.235671e-06 -3.834408e-17 -2.344496e-16 -3.757210e-18
## [62,] -5.026908e-06 1.779950e-16 -2.342464e-16 -3.665619e-18
## [63,] 4.179079e-06 -3.821846e-17 -2.344617e-16 -3.760869e-18
## [64,] 1.651438e-06 -3.809161e-17 -1.231066e-16 -3.689785e-18
## [65,] -3.631026e-06 -2.601899e-16 -1.237903e-16 -3.837553e-18
## [66,] -2.908033e-06 -2.485902e-16 -1.242138e-16 -4.026004e-18
## [67,] -8.994400e-07 -2.513592e-16 -2.347991e-16 -3.908206e-18
## [68,] 2.835096e-06 -2.569950e-16 -2.342576e-16 -3.743868e-18
## [69,] 4.251950e-06 -4.931441e-17 -2.337415e-16 -3.512309e-18
## [70,] 2.726296e-06 1.928603e-16 -2.351555e-16 -3.986553e-18
## [71,] -7.588799e-07 -2.539806e-16 -1.236969e-16 -3.869035e-18
## [72,] -6.114356e-06 -4.846266e-16 -2.344118e-16 -3.730730e-18
## [73,] -5.983345e-06 -2.595652e-16 -2.341836e-16 -3.706413e-18
## [74,] -2.610068e-06 -2.652766e-16 -2.339809e-16 -3.614874e-18
## [75,] 9.305150e-07 -2.594396e-16 -2.341957e-16 -3.710071e-18
## [76,] 1.406917e-06 -2.536782e-16 -2.347492e-16 -3.878067e-18
## [77,] 2.442610e-06 -4.871212e-16 -2.339990e-16 -3.620475e-18
## [78,] 2.181575e-06 -4.727072e-16 -2.348659e-16 -3.928492e-18
## [79,] 5.378099e-07 -2.477041e-16 -2.349771e-16 -3.977254e-18
## [80,] 2.704498e-06 -4.726340e-16 -2.352168e-16 -4.005177e-18
## [81,] 5.314147e-06 4.098330e-16 -2.350141e-16 -3.913638e-18
## [82,] 1.505026e-07 4.157398e-16 -2.348906e-16 -3.936088e-18
## [83,] -2.219537e-06 4.072082e-16 -2.342450e-16 -3.725036e-18
## [84,] -8.350039e-07 3.957341e-16 -2.338335e-16 -3.540244e-18
## [85,] -2.803645e-06 4.015712e-16 -2.340483e-16 -3.635441e-18
## [86,] -1.323833e-06 1.852880e-16 -2.346018e-16 -3.803436e-18
## [87,] -9.293805e-07 1.910667e-16 -2.351560e-16 -3.971712e-18
## [88,] -2.748829e-06 4.189483e-16 -2.353708e-16 -4.066909e-18
## [89,] -7.155347e-07 1.797892e-16 -2.340735e-16 -3.643089e-18
## [90,] -3.197462e-06 1.913306e-16 -2.348363e-16 -3.904619e-18
## [91,] -7.771885e-07 1.827292e-16 -2.345289e-16 -3.766314e-18
## [92,] -7.192831e-07 1.886360e-16 -2.344055e-16 -3.788764e-18
## [93,] -9.496971e-07 1.885823e-16 -2.350892e-16 -3.936532e-18
## [94,] 1.269632e-06 1.857609e-16 -2.349911e-16 -3.891761e-18
## [95,] 2.438528e-06 1.887718e-16 -2.347634e-16 -3.867496e-18
## [96,] 2.339272e-06 1.888462e-16 -2.347695e-16 -3.869439e-18
## [97,] 2.508152e-06 1.831872e-16 -2.342279e-16 -3.704874e-18
## [98,] -2.204487e-07 1.861457e-16 -2.343391e-16 -3.753636e-18
## [99,] -2.491943e-07 -3.012018e-17 -2.348933e-16 -3.921912e-18
## [100,] 7.262191e-07 -3.583160e-17 -2.346906e-16 -3.830374e-18
## [101,] 3.234111e-06 6.508864e-16 2.389697e-16 5.183586e-18
## [102,] -2.198372e-07 4.408982e-16 2.385024e-16 4.981833e-18
## [103,] 7.940606e-07 6.433838e-16 2.398616e-16 5.439449e-18
## [104,] -8.560336e-06 4.362797e-16 2.392892e-16 5.190877e-18
## [105,] -1.810026e-07 2.204707e-16 2.386912e-16 5.009298e-18
## [106,] 6.071593e-06 2.094010e-16 2.387200e-16 5.107762e-18
## [107,] -3.250112e-07 -3.395922e-18 1.276722e-16 5.025190e-18
## [108,] 2.892981e-06 -2.392839e-16 2.395046e-16 5.316141e-18
## [109,] -6.448176e-06 -4.578959e-16 2.393489e-16 5.253796e-18
## [110,] 2.741618e-06 -6.823461e-16 1.280409e-16 5.211906e-18
## [111,] -1.196394e-06 -9.843167e-18 1.281190e-16 5.175768e-18
## [112,] 3.619219e-06 -3.596217e-18 1.275200e-16 4.993857e-18
## [113,] -4.462268e-06 -2.279243e-16 1.279114e-16 5.097741e-18
## [114,] 4.212104e-06 3.181607e-18 1.268690e-16 4.796264e-18
## [115,] 1.169846e-07 2.200587e-16 2.383879e-16 4.946966e-18
## [116,] 4.934868e-06 4.253873e-16 2.393020e-16 5.284404e-18
## [117,] -7.371587e-06 4.374027e-16 2.384947e-16 5.009292e-18
## [118,] 1.204565e-06 2.186978e-16 2.380009e-16 4.874428e-18
## [119,] 3.709281e-06 4.298647e-16 2.390451e-16 5.191411e-18
## [120,] -2.748808e-06 2.141309e-16 2.387838e-16 5.082194e-18
## [121,] 1.404009e-06 4.453238e-16 2.380790e-16 4.853184e-18
## [122,] 4.018076e-06 4.372718e-16 2.386787e-16 5.050269e-18
## [123,] 1.145846e-06 4.291847e-16 2.389388e-16 5.174046e-18
## [124,] 1.193116e-06 6.575401e-16 2.386776e-16 5.064830e-18
## [125,] -9.104038e-06 2.139991e-16 2.386250e-16 5.048867e-18
## [126,] 6.324967e-08 2.116518e-16 2.386787e-16 5.080056e-18
## [127,] 3.639424e-06 4.370419e-16 2.381854e-16 4.945244e-18
## [128,] -1.065961e-06 2.184651e-16 2.383692e-16 4.956206e-18
## [129,] 4.568838e-06 2.161004e-16 2.384235e-16 4.987675e-18
## [130,] -1.874003e-05 8.941800e-16 2.372780e-16 4.639816e-18
## [131,] 3.738333e-06 2.315312e-16 2.374612e-16 4.650498e-18
## [132,] 7.163113e-06 6.703248e-16 2.372802e-16 4.655375e-18
## [133,] -4.495573e-06 2.296623e-16 2.371240e-16 4.592978e-18
## [134,] 3.096727e-07 4.523486e-16 2.377503e-16 4.723401e-18
## [135,] 4.326315e-06 4.528739e-16 2.377000e-16 4.708103e-18
## [136,] 2.270287e-07 2.312383e-16 2.369729e-16 4.547084e-18
## [137,] 1.521911e-07 6.817687e-18 2.370283e-16 4.578886e-18
## [138,] -1.037179e-05 2.323186e-16 2.372132e-16 4.590181e-18
## [139,] -2.216260e-06 -7.373359e-19 2.375813e-16 4.761723e-18
## [140,] 4.269946e-06 2.390681e-16 2.365660e-16 4.393637e-18
## [141,] 8.467314e-06 4.530552e-16 2.371672e-16 4.591107e-18
## [142,] -1.207322e-06 2.372520e-16 2.365697e-16 4.409581e-18
## [143,] 5.105419e-06 2.406500e-16 2.364153e-16 4.347796e-18
## [144,] -2.195066e-06 2.268594e-16 2.375663e-16 4.712211e-18
## [145,] -9.046945e-07 2.302346e-16 2.374141e-16 4.651092e-18
## [146,] -1.053616e-05 1.723430e-17 2.363743e-16 4.350332e-18
## [147,] -4.729600e-06 2.312510e-16 2.373166e-16 4.621494e-18
## [148,] 2.888890e-06 4.538095e-16 2.372674e-16 4.606529e-18
## [149,] 8.532213e-06 2.236262e-16 2.375314e-16 4.731584e-18
## [150,] -6.811891e-07 2.298676e-16 2.369339e-16 4.550058e-18
## [151,] 4.104380e-06 2.390342e-16 2.365713e-16 4.395072e-18
## [152,] -1.935822e-06 2.338206e-16 2.370702e-16 4.546668e-18
## [153,] 2.339847e-07 4.620838e-16 2.364749e-16 4.365807e-18
## [154,] -1.098031e-05 2.420724e-17 2.358792e-16 4.184894e-18
## [155,] -2.556467e-06 2.323915e-16 2.366919e-16 4.476562e-18
## [156,] -3.735380e-07 2.415466e-16 2.363304e-16 4.321909e-18
## [157,] -3.624699e-06 2.333965e-16 2.365955e-16 4.447297e-18
## [158,] -6.308855e-07 2.425516e-16 2.362340e-16 4.292644e-18
## [159,] 5.549440e-06 9.548120e-18 2.369410e-16 4.537213e-18
## [160,] 2.074027e-06 2.320952e-16 2.368928e-16 4.522580e-18
## [161,] 3.106293e-06 4.660627e-16 2.357494e-16 4.175386e-18
## [162,] -5.516800e-06 2.359204e-16 2.363535e-16 4.373801e-18
## [163,] 1.805124e-06 2.585704e-17 2.355495e-16 4.099686e-18
## [164,] 4.489856e-06 2.398450e-16 2.364935e-16 4.371461e-18
## [165,] 3.058560e-06 2.402312e-16 2.357687e-16 4.211107e-18
## [166,] -5.911280e-07 4.686517e-16 2.361901e-16 4.249326e-18
## [167,] -1.089818e-05 2.326829e-16 2.366650e-16 4.468301e-18
## [168,] -6.336012e-06 4.753555e-16 2.355472e-16 4.054113e-18
## [169,] -2.954654e-06 2.479810e-16 2.353694e-16 4.059988e-18
## [170,] -9.587222e-06 2.428316e-16 2.362082e-16 4.284715e-18
## [171,] -4.362484e-06 2.462127e-16 2.360564e-16 4.223648e-18
## [172,] 1.801774e-06 2.438023e-16 2.361151e-16 4.256447e-18
## [173,] -2.021754e-06 2.796489e-17 2.355209e-16 4.075919e-18
## [174,] -1.785386e-06 2.561935e-16 2.349268e-16 3.895618e-18
## [175,] -8.910474e-06 2.452700e-16 2.359754e-16 4.213932e-18
## [176,] -1.756025e-06 4.676835e-16 2.352511e-16 4.053858e-18
## [177,] -3.321963e-07 2.576726e-16 2.347860e-16 3.852770e-18
## [178,] -4.956194e-06 2.409109e-16 2.357045e-16 4.191538e-18
## [179,] 1.036727e-06 2.414603e-16 2.359968e-16 4.250317e-18
## [180,] 5.518673e-06 4.783473e-16 2.350899e-16 3.930049e-18
## [181,] 1.848335e-06 2.538924e-16 2.351485e-16 3.962848e-18
## [182,] 8.010950e-06 3.520603e-17 2.349990e-16 3.902446e-18
## [183,] 3.141599e-06 3.855835e-17 2.348490e-16 3.841992e-18
## [184,] 3.812764e-06 2.438298e-16 2.357685e-16 4.181092e-18
## [185,] -6.570156e-06 2.586199e-16 2.345227e-16 3.787797e-18
## [186,] 1.600829e-06 2.562268e-16 2.345808e-16 3.820316e-18
## [187,] 6.857300e-06 2.452164e-16 2.352916e-16 4.066163e-18
## [188,] -1.467050e-07 4.096251e-17 2.346194e-16 3.772206e-18
## [189,] -1.512335e-06 2.519966e-16 2.353303e-16 4.018053e-18
## [190,] 1.396702e-04 -4.022486e-16 3.452126e-16 1.146942e-16
## [191,] -9.265683e-07 3.372604e-17 2.347970e-16 3.870989e-18
## [192,] 1.870531e-06 2.561864e-16 2.344132e-16 3.784328e-18
## [193,] -3.801739e-06 3.172010e-17 2.344729e-16 3.817460e-18
## [194,] 2.647365e-06 2.514127e-16 2.348710e-16 3.923338e-18
## [195,] 6.469553e-06 2.461822e-16 2.353725e-16 4.075651e-18
## [196,] 4.372886e-06 2.609435e-16 2.341285e-16 3.682968e-18
## [197,] 3.555043e-06 2.557771e-16 2.349699e-16 3.908413e-18
## [198,] -3.622911e-06 4.278363e-17 2.342734e-16 3.682011e-18
## [199,] 4.005384e-06 2.311501e-17 2.352992e-16 4.068263e-18
## [200,] -1.209343e-04 7.040626e-16 2.343940e-16 1.147709e-165 Dimension Reduction
To keep 90% information of data, nased on th ecummulative proportion, the selected pca shall be PC1 to PC5.
summary(pca)## Importance of components:
## PC1 PC2 PC3 PC4 PC5 PC6 PC7
## Standard deviation 4.3587 2.2053 2.1001 1.41814 1.16670 0.80858 0.65007
## Proportion of Variance 0.5588 0.1430 0.1297 0.05915 0.04003 0.01923 0.01243
## Cumulative Proportion 0.5588 0.7018 0.8315 0.89068 0.93072 0.94995 0.96238
## PC8 PC9 PC10 PC11 PC12 PC13 PC14
## Standard deviation 0.57845 0.50289 0.43500 0.35671 0.3350 0.27127 0.24478
## Proportion of Variance 0.00984 0.00744 0.00557 0.00374 0.0033 0.00216 0.00176
## Cumulative Proportion 0.97222 0.97965 0.98522 0.98896 0.9923 0.99443 0.99619
## PC15 PC16 PC17 PC18 PC19 PC20 PC21
## Standard deviation 0.20911 0.1934 0.13818 0.13666 0.06954 0.04145 0.03368
## Proportion of Variance 0.00129 0.0011 0.00056 0.00055 0.00014 0.00005 0.00003
## Cumulative Proportion 0.99748 0.9986 0.99914 0.99969 0.99983 0.99988 0.99991
## PC22 PC23 PC24 PC25 PC26 PC27
## Standard deviation 0.03240 0.02996 0.02312 0.01546 0.01364 0.003017
## Proportion of Variance 0.00003 0.00003 0.00002 0.00001 0.00001 0.000000
## Cumulative Proportion 0.99995 0.99997 0.99999 0.99999 1.00000 1.000000
## PC28 PC29 PC30 PC31 PC32
## Standard deviation 0.001506 0.0007818 5.366e-05 1.368e-05 4.211e-16
## Proportion of Variance 0.000000 0.0000000 0.000e+00 0.000e+00 0.000e+00
## Cumulative Proportion 1.000000 1.0000000 1.000e+00 1.000e+00 1.000e+00
## PC33 PC34
## Standard deviation 4.211e-16 4.211e-16
## Proportion of Variance 0.000e+00 0.000e+00
## Cumulative Proportion 1.000e+00 1.000e+00pc_keep <- pca$x %>% as.data.frame() %>% select(c(PC1,PC2,PC3,PC4,PC5))
pc_keep## PC1 PC2 PC3 PC4 PC5
## 1 -4.856981 0.286039318 -3.167108725 1.086529787 0.9960426524
## 2 -4.568612 0.216107212 -4.421660395 0.398151859 0.5158896563
## 3 -4.374270 0.119649913 -4.847848921 -0.558824610 0.2037943658
## 4 -4.108053 0.044754039 -5.151540707 -1.270092145 -0.0785613337
## 5 -3.711520 2.385509601 -5.337098323 -2.041766339 -0.4463138432
## 6 -3.758451 -0.019436735 -5.474794022 -1.935408052 -0.5084295896
## 7 -3.709848 -0.012463956 -5.488350570 -1.865546151 -0.6428690365
## 8 -3.691217 0.002562939 -5.456567075 -1.708104358 -0.7657935159
## 9 -3.831441 0.154907762 -5.267703190 0.094574055 -0.2466408307
## 10 -3.861637 0.195145585 -5.183403590 0.560944097 -0.2565561770
## 11 -3.314913 0.143932909 -4.724686295 0.892225541 -0.2284598266
## 12 -3.408300 0.138919214 -4.559203702 0.855493334 -0.2316327497
## 13 -3.467702 0.108669687 -4.378559270 0.566613893 -0.2652835426
## 14 -3.483273 0.071911250 -4.287724474 0.182749281 -0.3122391268
## 15 -3.438707 0.042979891 -4.279759626 -0.117479582 -0.3520170696
## 16 -3.344062 0.033984010 -4.245073017 -0.180169865 -0.3030422774
## 17 -3.305345 0.052353972 -4.219058188 0.022344559 -0.2835774379
## 18 -3.316693 0.084450677 -4.143289107 0.370439115 -0.2450350582
## 19 -3.403649 0.113575356 -4.009979508 0.658421958 -0.2111449649
## 20 -3.472514 0.114527896 -3.791724709 0.716728124 -0.2049983667
## 21 -3.859052 0.099656192 -3.098183330 0.517453993 -0.1889106097
## 22 -3.927427 0.071502346 -2.983175229 0.166758776 -0.1652611453
## 23 -3.920517 0.043180003 -2.911819999 -0.139013401 -0.2053341434
## 24 -3.862111 0.031868285 -2.907430175 -0.246806260 -0.2230432443
## 25 -3.826230 0.046762559 -2.872960626 -0.095297660 -0.1450445691
## 26 -4.231474 0.088598680 -2.145676841 0.233104208 0.0139109614
## 27 -4.258687 0.109453236 -1.968015129 0.516019647 0.0433157050
## 28 -4.383042 0.119012336 -1.760896167 0.579030555 0.1158800202
## 29 -4.480434 0.104409061 -1.555827661 0.421518193 0.0936866913
## 30 -4.528685 0.078144699 -1.440110249 0.150492359 -0.0081324029
## 31 -4.490913 0.046391831 -1.337390106 -0.132299498 -0.0455306247
## 32 -4.468840 0.034402609 -1.287964686 -0.280223808 -0.0005006356
## 33 -4.460963 0.043250738 -1.263874041 -0.214277206 -0.0026628827
## 34 -4.438778 0.063648472 -1.186362691 0.035904266 0.0224924249
## 35 -4.474592 0.083982757 -1.007484573 0.299219613 -0.0154055567
## 36 -4.533340 0.092243780 -0.758695127 0.443328726 -0.0007958397
## 37 -4.623486 0.085848312 -0.548900240 0.384516190 -0.0093107270
## 38 -4.718987 0.069994114 -0.366780059 0.186193156 -0.0294316320
## 39 -4.708832 0.043432824 -0.199139147 -0.031976430 -0.0594060972
## 40 -4.741828 0.030860244 -0.123501358 -0.221792095 -0.0207508459
## 41 -4.429143 0.017941518 -0.473797432 -0.216550980 -0.0332604257
## 42 -4.414203 0.028131380 -0.465171965 -0.132032706 0.0300117766
## 43 -4.429832 0.046996483 -0.361009401 0.077129452 0.0486187519
## 44 -4.509206 0.066097829 -0.169342450 0.254362681 0.1345097786
## 45 -4.585047 0.071903879 0.051159130 0.322734691 0.2017111798
## 46 -4.676473 0.071361449 0.286904771 0.326503372 0.1977733664
## 47 -4.786548 0.067176698 0.476251959 0.234653551 0.2471534906
## 48 -4.857457 0.053453838 0.695137731 0.079092026 0.2917018802
## 49 -4.886236 0.034241003 0.873565024 -0.117970018 0.3234307810
## 50 -4.878609 0.018602102 1.051763335 -0.237745781 0.2986027244
## 51 -4.903928 0.017111554 1.212486356 -0.255806837 0.2860042159
## 52 -4.919056 0.021689488 1.359989436 -0.192838302 0.2836978121
## 53 -4.940566 0.026929962 1.573763875 -0.081525553 0.2248181216
## 54 -4.981071 0.031299883 1.807895559 0.007366967 0.2276838968
## 55 -5.077694 0.035971640 2.005037890 0.026762521 0.2267049950
## 56 -5.123709 0.028357934 2.229269749 0.018634188 0.0779345712
## 57 -5.136221 0.018337976 2.418900238 0.039845509 -0.1896330617
## 58 -5.132945 0.008106047 2.614215205 0.029704610 -0.2461611895
## 59 -5.157023 0.001610077 2.743930563 0.001577062 -0.3167240857
## 60 -4.933270 3.246328697 2.868845974 -0.347707465 -0.5719213934
## 61 -5.002309 -0.030519676 2.712537011 -0.155423786 -0.5311869361
## 62 -4.738995 -0.057040936 1.801562839 -0.377284499 -0.9567964354
## 63 -4.201769 -0.093075806 0.557876753 -0.563414042 -1.4021484046
## 64 -3.716412 0.013995849 -0.225828806 -1.856076040 6.6390386471
## 65 -4.457116 0.005046865 0.890463665 -0.789741958 1.7567321531
## 66 -4.237534 0.037681472 0.537951881 0.115925281 0.4788084353
## 67 -4.152236 0.066479364 0.444205244 0.742644064 -0.1048643829
## 68 -4.164992 0.068028083 0.505192405 0.985643631 -0.5192590326
## 69 -4.195870 0.039575963 0.593416652 0.847814651 -0.8460034790
## 70 -4.238823 0.001290017 0.566403475 0.453429793 -1.0020927084
## 71 -4.041191 0.027863406 0.199914369 -0.895211644 4.3246900823
## 72 -4.488515 -0.035718673 0.977319116 -0.820282310 1.1435573789
## 73 -4.239395 -0.059059762 0.673855156 -0.715784626 0.3280331726
## 74 -4.059799 -0.045247902 0.467636985 -0.402114059 0.0290497769
## 75 -3.968710 -0.012922980 0.351700065 0.056003158 -0.1789446389
## 76 -3.982340 0.019143791 0.358923389 0.446362724 -0.2566626717
## 77 -4.007046 0.028461318 0.427765476 0.632091160 -0.3636058010
## 78 -4.091471 0.015221940 0.528967874 0.495329263 -0.4415110511
## 79 -4.098252 -0.018273608 0.538810641 0.165373649 -0.5416203249
## 80 -4.058900 -0.051051868 0.490332464 -0.167017696 -0.6502918592
## 81 -4.193346 -0.086308900 2.537879353 -0.207673378 -0.0875457154
## 82 -4.360608 -0.048369881 3.018185039 0.068086341 0.3297141433
## 83 -4.473604 -0.028399450 3.292883021 0.251568029 0.4608307344
## 84 -4.588520 -0.028465282 3.572204568 0.248016473 0.5128461971
## 85 -4.676065 -0.040750399 3.741047394 0.113691358 0.4875350917
## 86 -4.736589 -0.060150180 3.859502844 -0.087701823 0.3797639458
## 87 -4.733657 -0.081277839 3.907621285 -0.270729132 0.2203196309
## 88 -4.696474 -0.098968475 3.960578446 -0.397568256 0.0670988662
## 89 -4.607533 -0.113417495 3.974046171 -0.466076519 -0.0131734354
## 90 -4.559522 -0.114581124 3.937940889 -0.464894383 -0.0810576921
## 91 -4.508957 -0.108099971 3.967608292 -0.344860407 -0.1425182674
## 92 -4.491039 -0.092501437 3.987005450 -0.160372087 -0.1244933051
## 93 -4.514015 -0.077219544 4.034064245 0.016017705 -0.1717280582
## 94 -4.522951 -0.072827522 4.073821388 0.142655518 -0.3687003415
## 95 -4.529593 -0.077917423 4.121713847 0.162080823 -0.4971838832
## 96 -4.531550 -0.091867503 4.190435221 0.085619352 -0.6310593910
## 97 -4.492019 -0.106886716 4.189340456 0.009532854 -0.7702387678
## 98 -4.462595 -0.122317517 4.205273670 -0.111857328 -0.8436532070
## 99 -4.460064 -0.130867918 4.258666838 -0.224841074 -0.7848737201
## 100 -4.424564 -0.135442016 4.243959697 -0.283660022 -0.7267018835
## 101 4.916351 -0.854079668 0.783361364 -2.251121951 0.8919800811
## 102 4.747088 -0.906941677 0.816633911 -2.332462321 -1.0882204634
## 103 5.052825 -0.888271370 0.598674418 -3.226951290 2.6766508758
## 104 4.605943 -0.972939763 0.901613600 -3.470080940 -0.4298838481
## 105 4.711115 -1.040549605 0.612615885 -3.917215189 -1.5569738538
## 106 4.970053 -1.060510357 0.279050941 -4.899678186 0.7445147806
## 107 4.726742 -1.136323772 0.402884534 -5.208787166 -1.5250084573
## 108 5.065794 -1.129340207 0.059255365 -6.473158259 2.6996708665
## 109 4.570992 -1.214522526 0.476815167 -6.610983173 -0.7681311342
## 110 4.693720 -1.278001293 0.146075480 -6.975473677 -1.9746163179
## 111 4.561367 -1.038844095 -0.178553186 -4.223363225 -2.6427413201
## 112 4.718175 -0.992941701 -0.293091695 -4.271292982 -0.9864303799
## 113 4.606146 -0.998597089 -0.293329925 -3.842051347 -2.7008995989
## 114 4.714785 -0.944870416 -0.291910367 -4.073685417 -0.3627327181
## 115 4.157154 -0.636610482 0.224724638 0.220098662 -1.0259159068
## 116 4.417509 -0.556757885 0.102148636 -0.085808982 3.0244798610
## 117 3.931124 -0.561678181 0.565014761 0.621810622 0.0112191256
## 118 4.014321 -0.548905917 0.340384797 1.086765345 -0.8676702907
## 119 4.265134 -0.500694742 0.128034117 0.917741123 1.7408540909
## 120 3.911598 -0.519048361 0.451668748 1.271280468 -0.3595761616
## 121 3.942642 -0.539970255 0.325531706 1.323199068 -1.1474350806
## 122 4.106280 -0.534691318 0.248053322 0.855777440 0.7432539396
## 123 3.934363 -0.575541330 0.370593455 0.885962278 -0.9600887755
## 124 4.217976 -0.550314110 0.194138882 0.144027919 2.4420173991
## 125 3.890037 -0.591746967 0.510590423 0.387046591 -0.2270501120
## 126 4.056084 -0.603714873 0.272195262 0.581053735 -1.0527176821
## 127 4.347986 -0.556382707 -0.035151311 0.421317164 1.2942634809
## 128 4.104976 -0.557123088 0.189657793 0.939995493 -0.6132629482
## 129 4.182210 -0.549093402 0.025145090 1.302820970 -1.2905033316
## 130 5.643394 17.763983425 0.476269875 -0.303535305 -0.0841317939
## 131 4.070640 -0.539919291 0.085836219 1.325616103 -1.1903380152
## 132 4.270573 -0.512445170 -0.020738020 0.606818532 2.1646078302
## 133 3.901872 -0.564553159 0.297392640 0.692205240 -0.4008301927
## 134 4.066006 -0.599873745 0.097877522 0.656040637 -1.2496214738
## 135 4.359243 -0.568611789 -0.146076544 0.278305573 1.2543381365
## 136 4.131306 -0.578602618 0.071568968 0.729401972 -0.8425088524
## 137 4.453952 -0.497961363 -0.143609824 0.307292587 3.5806691639
## 138 3.931272 -0.514222929 0.365558174 0.972507554 0.3316839589
## 139 4.005623 -0.525989716 0.245311192 1.265071038 -0.7213361380
## 140 4.071683 -0.542114144 0.022064625 1.302157552 -1.3139243471
## 141 4.268126 -0.545196108 -0.091229392 0.804829766 0.4012109071
## 142 4.168377 -0.590605484 -0.190481265 0.813669518 -1.3187556261
## 143 4.374987 -0.569196312 -0.266187655 0.343423012 0.9679411571
## 144 4.224085 -0.587993073 -0.090080265 0.696904090 -0.9015220886
## 145 4.483561 -0.518783293 -0.231401809 0.369587983 2.7356347877
## 146 4.026802 -0.522485074 0.165646859 0.967800034 0.1162069633
## 147 4.099801 -0.526212750 0.044261020 1.273111486 -0.7053515530
## 148 4.173682 -0.539524545 -0.108552805 1.371429129 -1.2953723626
## 149 4.315685 -0.534128941 -0.184986821 0.965005220 0.3391784074
## 150 4.191308 -0.576380621 -0.200435353 0.987631499 -1.2980346940
## 151 4.364419 -0.561644253 -0.233559555 0.478721774 0.8580014053
## 152 4.196928 -0.589732347 -0.035596191 0.699387592 -0.9690826797
## 153 4.456545 -0.531437441 -0.216503315 0.273026351 2.5222020419
## 154 4.065011 -0.542404182 0.151299073 0.826714123 -0.1072482904
## 155 4.158048 -0.542191244 0.034880503 1.174599560 -0.9135646298
## 156 4.343386 -0.503921608 -0.139269027 0.936301390 1.3637805242
## 157 4.069762 -0.528619360 0.094866091 1.179536192 -0.5115317308
## 158 4.127020 -0.550986395 -0.027289616 1.200637191 -1.2253105776
## 159 4.293720 -0.549092668 -0.058026273 0.782094245 0.3947387371
## 160 4.165024 -0.581016618 0.031761049 0.879571308 -1.1728377660
## 161 4.382380 -0.546498857 -0.081357705 0.330811295 1.8091704759
## 162 4.105452 -0.574013160 0.210631504 0.681491920 -0.5423827381
## 163 4.194322 -0.574265689 0.042147844 0.937688763 -1.2716265087
## 164 4.421453 -0.535807960 -0.048810985 0.791742170 0.8610904411
## 165 4.164636 -0.541716842 0.116817126 1.187741551 -0.9244098496
## 166 4.412331 -0.490505196 0.001761828 0.665790054 2.7944338924
## 167 3.958752 -0.528615466 0.448764925 0.965004959 0.0588174388
## 168 4.013026 -0.553982233 0.306137247 0.996790065 -0.8669574864
## 169 4.276838 -0.538179662 0.094216173 0.441153780 1.6915215485
## 170 4.058089 -0.573986953 0.311427322 0.629876310 -0.3571781906
## 171 4.181513 -0.584575241 0.143685226 0.793191635 -1.0751538069
## 172 4.402465 -0.551363868 -0.018043645 0.642354387 0.7653799350
## 173 4.198172 -0.553529360 0.121591308 1.033831143 -0.8059721585
## 174 4.399579 -0.500291193 -0.002029387 0.699283106 2.2470570703
## 175 4.042607 -0.525801679 0.338029781 1.059474981 -0.0788284244
## 176 4.088069 -0.542436465 0.193016202 1.158024480 -0.8981793832
## 177 4.286362 -0.529906990 0.010905743 0.717793802 1.0896918545
## 178 4.119190 -0.569816917 0.175185193 0.802801848 -0.6884279763
## 179 4.256928 -0.590072960 -0.033684511 0.842111808 -1.3272983981
## 180 4.418281 -0.567498573 -0.134745477 0.661921199 0.0644455360
## 181 4.352942 -0.577061298 -0.189444882 1.028033344 -1.4323724422
## 182 4.496677 -0.533166211 -0.178180592 0.872935813 0.6642154199
## 183 4.252941 -0.541375980 -0.025711003 1.236907353 -1.0454443313
## 184 4.504030 -0.497979750 -0.136814523 0.748101234 2.3120396446
## 185 4.054377 -0.533846556 0.261117636 1.009096080 -0.3518842639
## 186 4.145439 -0.562950471 0.115396378 1.016456901 -1.1957768409
## 187 4.411757 -0.546176555 -0.097580847 0.580129474 1.0515223282
## 188 4.200218 -0.572006491 0.054301779 0.815087146 -0.8971112163
## 189 4.550432 -0.518861109 -0.142103800 0.301373942 2.9430819336
## 190 5.401743 17.278781485 0.788839873 -0.626618791 -0.4579676967
## 191 4.179360 -0.545209642 0.125531631 1.092569351 -0.8619907023
## 192 4.414989 -0.507850853 -0.067608118 0.785284431 1.6598954466
## 193 4.118321 -0.535306411 0.215138521 1.058122219 -0.4439306924
## 194 4.218644 -0.558020484 0.032261489 1.103586868 -1.1727059927
## 195 4.426192 -0.548715152 -0.079397519 0.741645233 0.5384378107
## 196 4.242722 -0.571310918 0.013725282 0.909757490 -1.0961123068
## 197 4.539485 -0.533972166 -0.135575968 0.444707012 1.9878713667
## 198 4.187865 -0.552581984 0.130909387 0.854572422 -0.4479262393
## 199 4.317865 -0.559840896 -0.034241751 1.126836481 -1.2489203503
## 200 5.819809 17.221573360 0.307135960 -0.501276541 0.2862917021As we know that PCA value reduce potential for munticollinearity. To prove that, below the correlation between variables from raw data.
6 Variables Correalation before and after PCA
ggcorr(Penicillin)## Warning in cor(data, use = method[1], method = method[2]): the standard
## deviation is zero
Anf below is the correlation of each PC.
ggcorr(pca$x)
7 Visualizing PCA
To get better understanding of each PC, plotting PC using biplot are required like below.
biplot(pca,
cex = 0.5, #
scale = F, #
choices = c(1,34)) # 
biplot(pca, scale = F, cex = 0.6)
The group of data and the arrow show the correaltion of data relative to
other pc.
fviz_contrib(X = pca, axes = 1, choice = "var")
Contribution of each variables shown from figure above. The variable which have contribution below the red line categorized as less contributor variable.
Penicillin_pca <- PCA(X = Penicillin_clean, #
scale.unit = T, #
graph = F, #
ncp = 8)Penicillin_pca$ind$coord %>% as.data.frame()## Dim.1 Dim.2 Dim.3 Dim.4 Dim.5 Dim.6
## 1 -4.869169 0.286757109 -3.175056312 -1.089256340 0.9985421360 -0.134147874
## 2 -4.580076 0.216649515 -4.432756173 -0.399150987 0.5171842371 -0.126768636
## 3 -4.385247 0.119950164 -4.860014182 0.560226933 0.2043057703 -0.061485742
## 4 -4.118362 0.044866346 -5.164468056 1.273279333 -0.0787584766 -0.067099112
## 5 -3.720834 2.391495833 -5.350491314 2.046889977 -0.4474338295 0.295940503
## 6 -3.767883 -0.019485510 -5.488532548 1.940264793 -0.5097054500 0.654374268
## 7 -3.719158 -0.012495233 -5.502123115 1.870227579 -0.6444822612 1.026296681
## 8 -3.700480 0.002569371 -5.470259862 1.712390700 -0.7677152091 1.404186670
## 9 -3.841055 0.155296490 -5.280922039 -0.094811380 -0.2472597547 -0.215601441
## 10 -3.871327 0.195635286 -5.196410897 -0.562351738 -0.2571999827 -0.229675629
## 11 -3.323231 0.144294097 -4.736542490 -0.894464504 -0.2290331269 -0.316883048
## 12 -3.416853 0.139267820 -4.570644632 -0.857640121 -0.2322140122 -0.277124593
## 13 -3.476404 0.108942384 -4.389546889 -0.568035762 -0.2659492489 -0.230722426
## 14 -3.492014 0.072091705 -4.298484151 -0.183207875 -0.3130226641 -0.201148390
## 15 -3.447336 0.043087745 -4.290499316 0.117774387 -0.3529004263 -0.203324733
## 16 -3.352454 0.034069290 -4.255725663 0.180621986 -0.3038027360 -0.217633296
## 17 -3.313639 0.052485350 -4.229645552 -0.022400631 -0.2842890511 -0.256792313
## 18 -3.325016 0.084662599 -4.153686336 -0.371368700 -0.2456499527 -0.286426868
## 19 -3.412191 0.113860363 -4.020042208 -0.660074212 -0.2116748151 -0.285671671
## 20 -3.481228 0.114815294 -3.801239717 -0.718526691 -0.2055127926 -0.263282163
## 21 -3.868736 0.099906271 -3.105957956 -0.518752499 -0.1893846647 -0.141443674
## 22 -3.937282 0.071681775 -2.990661251 -0.167177243 -0.1656758540 -0.108669414
## 23 -3.930355 0.043288359 -2.919126961 0.139362244 -0.2058494118 -0.100112892
## 24 -3.871803 0.031948256 -2.914726122 0.247425599 -0.2236029522 -0.123674412
## 25 -3.835831 0.046879906 -2.880170074 0.095536802 -0.1454085460 -0.168055865
## 26 -4.242092 0.088821011 -2.151061233 -0.233689163 0.0139458698 -0.183845845
## 27 -4.269374 0.109727899 -1.972953694 -0.517314554 0.0434244020 -0.196957404
## 28 -4.394041 0.119310988 -1.765314985 -0.580483583 0.1161708112 -0.175461248
## 29 -4.491677 0.104671067 -1.559731877 -0.422575957 0.0939217900 -0.139586892
## 30 -4.540049 0.078340797 -1.443724082 -0.150870007 -0.0081528104 -0.104276718
## 31 -4.502182 0.046508248 -1.340746172 0.132631492 -0.0456448799 -0.095091660
## 32 -4.480054 0.034488939 -1.291196723 0.280927006 -0.0005018919 -0.110237544
## 33 -4.472157 0.043359272 -1.267045625 0.214814916 -0.0026695650 -0.141494237
## 34 -4.449917 0.063808192 -1.189339767 -0.035994365 0.0225488677 -0.171516202
## 35 -4.485820 0.084193505 -1.010012769 -0.299970479 -0.0154442156 -0.175819327
## 36 -4.544716 0.092475258 -0.760599007 -0.444441222 -0.0007978368 -0.163061800
## 37 -4.635088 0.086063741 -0.550277658 -0.385481101 -0.0093340915 -0.128251104
## 38 -4.730829 0.070169758 -0.367700462 -0.186660391 -0.0295054882 -0.083377646
## 39 -4.720648 0.043541815 -0.199638870 0.032056673 -0.0595551717 -0.072293540
## 40 -4.753727 0.030937685 -0.123811274 0.222348663 -0.0208029184 -0.072323182
## 41 -4.440258 0.017986541 -0.474986386 0.217094396 -0.0333438898 -0.123717722
## 42 -4.425280 0.028201974 -0.466339274 0.132364031 0.0300870886 -0.160346236
## 43 -4.440949 0.047114417 -0.361915324 -0.077323001 0.0487407565 -0.182434860
## 44 -4.520521 0.066263696 -0.169767400 -0.255000982 0.1348473193 -0.186321335
## 45 -4.596553 0.072084316 0.051287509 -0.323544566 0.2022173567 -0.186102898
## 46 -4.688208 0.071540525 0.287624734 -0.327322704 0.1982696617 -0.167126356
## 47 -4.798560 0.067345272 0.477447073 -0.235242394 0.2477737011 -0.148711450
## 48 -4.869647 0.053587976 0.696882119 -0.079290501 0.2924338811 -0.133058641
## 49 -4.898498 0.034326928 0.875757160 0.118266053 0.3242424028 -0.137415103
## 50 -4.890851 0.018648782 1.054402645 0.238342383 0.2993520423 -0.148339192
## 51 -4.916234 0.017154494 1.215528987 0.256448762 0.2867219190 -0.160697453
## 52 -4.931400 0.021743916 1.363402213 0.193322214 0.2844097274 -0.175306077
## 53 -4.952964 0.026997540 1.577713100 0.081730135 0.2253822834 -0.176327588
## 54 -4.993570 0.031378427 1.812432318 -0.007385454 0.2282552500 -0.175715733
## 55 -5.090436 0.036061908 2.010069361 -0.026829680 0.2272738917 -0.156496414
## 56 -5.136566 0.028429096 2.234863910 -0.018680949 0.0781301413 -0.137071812
## 57 -5.149110 0.018383993 2.424970261 -0.039945497 -0.1901089296 -0.087970915
## 58 -5.145826 0.008126388 2.620775354 -0.029779151 -0.2467789099 -0.039407526
## 59 -5.169964 0.001614118 2.750816221 -0.001581019 -0.3175188777 -0.013431410
## 60 -4.945649 3.254475080 2.876045097 0.348580007 -0.5733565811 0.011309087
## 61 -5.014862 -0.030596262 2.719343890 0.155813808 -0.5325199042 0.060690598
## 62 -4.750887 -0.057184076 1.806083707 0.378231262 -0.9591974340 0.006941481
## 63 -4.212313 -0.093309372 0.559276697 0.564827881 -1.4056669758 -0.022920057
## 64 -3.725739 0.014030970 -0.226395504 1.860733703 6.6556987452 0.788200014
## 65 -4.468301 0.005059530 0.892698208 0.791723748 1.7611405218 -0.556377677
## 66 -4.248167 0.037776030 0.539301826 -0.116216185 0.4800099640 -0.454515873
## 67 -4.162656 0.066646188 0.445319939 -0.744507666 -0.1051275311 -0.316854950
## 68 -4.175444 0.068198794 0.506460142 -0.988117020 -0.5205620686 -0.175946127
## 69 -4.206399 0.039675275 0.594905780 -0.849942169 -0.8481264522 -0.035747790
## 70 -4.249460 0.001293254 0.567824816 -0.454567636 -1.0046073741 0.078294017
## 71 -4.051332 0.027933326 0.200416037 0.897458101 4.3355425211 0.655206958
## 72 -4.499779 -0.035808306 0.979771615 0.822340738 1.1464270380 -0.187585746
## 73 -4.250033 -0.059207967 0.675546137 0.717580826 0.3288563437 -0.139825116
## 74 -4.069987 -0.045361448 0.468810480 0.403123129 0.0291226748 -0.120541518
## 75 -3.978669 -0.012955409 0.352582626 -0.056143693 -0.1793936851 -0.116710075
## 76 -3.992334 0.019191831 0.359824076 -0.447482833 -0.2573067446 -0.093293252
## 77 -4.017101 0.028532740 0.428838917 -0.633677338 -0.3645182386 -0.057737852
## 78 -4.101738 0.015260138 0.530295273 -0.496572249 -0.4426189852 0.005466036
## 79 -4.108536 -0.018319464 0.540162740 -0.165788640 -0.5429794746 0.056420910
## 80 -4.069086 -0.051179978 0.491562911 0.167436812 -0.6519237109 0.076739595
## 81 -4.203869 -0.086525484 2.544247943 0.208194516 -0.0877654039 0.339373413
## 82 -4.371550 -0.048491261 3.025758916 -0.068257197 0.3305415327 0.250027431
## 83 -4.484830 -0.028470716 3.301146228 -0.252199317 0.4619871496 0.197979794
## 84 -4.600035 -0.028536713 3.581168709 -0.248638849 0.5141331407 0.200732583
## 85 -4.687799 -0.040852659 3.750435232 -0.113976656 0.4887585192 0.219283872
## 86 -4.748475 -0.060301121 3.869187936 0.087921903 0.3807169309 0.238673071
## 87 -4.745536 -0.081481798 3.917427125 0.271408504 0.2208725041 0.267099301
## 88 -4.708260 -0.099216828 3.970517178 0.398565919 0.0672672450 0.281139216
## 89 -4.619096 -0.113702107 3.984018699 0.467246098 -0.0132064931 0.271566558
## 90 -4.570964 -0.114868656 3.947822814 0.466060996 -0.0812610994 0.261955232
## 91 -4.520272 -0.108371239 3.977564665 0.345725804 -0.1428759048 0.238088812
## 92 -4.502309 -0.092733562 3.997010499 0.160774527 -0.1248057104 0.220375519
## 93 -4.525342 -0.077413319 4.044187383 -0.016057900 -0.1721589951 0.222251788
## 94 -4.534301 -0.073010277 4.084044294 -0.143013500 -0.3696255633 0.233193539
## 95 -4.540960 -0.078112950 4.132056934 -0.162487551 -0.4984315235 0.278668305
## 96 -4.542922 -0.092098037 4.200950759 -0.085834206 -0.6326429804 0.333745493
## 97 -4.503291 -0.107154939 4.199853246 -0.009556775 -0.7721716159 0.366898002
## 98 -4.473794 -0.122624463 4.215826443 0.112138024 -0.8457702823 0.398448129
## 99 -4.471257 -0.131196319 4.269353597 0.225405293 -0.7868432934 0.410029199
## 100 -4.435667 -0.135781896 4.254609550 0.284371842 -0.7285254795 0.391945856
## 101 4.928688 -0.856222907 0.785327143 2.256770948 0.8942184286 -2.981887804
## 102 4.759000 -0.909217569 0.818683183 2.338315435 -1.0909512593 -3.361394424
## 103 5.065505 -0.890500411 0.600176740 3.235049048 2.6833677016 -2.794846657
## 104 4.617501 -0.975381272 0.903876122 3.478788810 -0.4309626048 -3.054294456
## 105 4.722937 -1.043160775 0.614153192 3.927045104 -1.5608809462 -2.549383729
## 106 4.982524 -1.063171617 0.279751195 4.911973508 0.7463830766 -1.702550870
## 107 4.738603 -1.139175279 0.403895538 5.221858170 -1.5288353352 -1.700806631
## 108 5.078506 -1.132174189 0.059404061 6.489402094 2.7064454590 -0.683103225
## 109 4.582463 -1.217570267 0.478011694 6.627572868 -0.7700586934 -1.034528214
## 110 4.705498 -1.281208327 0.146442044 6.992978030 -1.9795714482 -0.533293568
## 111 4.572813 -1.041450985 -0.179001250 4.233961393 -2.6493730528 3.255820438
## 112 4.730015 -0.995433403 -0.293827183 4.282011426 -0.9889057423 3.946895311
## 113 4.617705 -1.001102983 -0.294066012 3.851692645 -2.7076772748 4.089538802
## 114 4.726616 -0.947241488 -0.292642891 4.083907981 -0.3636429647 4.788354115
## 115 4.167586 -0.638208002 0.225288565 -0.220650981 -1.0284903548 -0.018691357
## 116 4.428594 -0.558155022 0.102404969 0.086024313 3.0320695339 0.498567235
## 117 3.940988 -0.563087664 0.566432617 -0.623371003 0.0112472790 -0.216914886
## 118 4.024394 -0.550283350 0.341238964 -1.089492489 -0.8698476349 -0.155505759
## 119 4.275837 -0.501951192 0.128355407 -0.920044115 1.7452226149 0.297089034
## 120 3.921414 -0.520350868 0.452802172 -1.274470638 -0.3604784872 -0.125393936
## 121 3.952535 -0.541325264 0.326348599 -1.326519522 -1.1503144705 -0.015482109
## 122 4.116585 -0.536033080 0.248675791 -0.857924940 0.7451190716 0.337709776
## 123 3.944236 -0.576985601 0.371523428 -0.888185525 -0.9624980360 0.028742654
## 124 4.228561 -0.551695076 0.194626057 -0.144389345 2.4481454323 0.517130781
## 125 3.899799 -0.593231905 0.511871706 -0.388017851 -0.2276198748 -0.115929929
## 126 4.066263 -0.605229844 0.272878312 -0.582511839 -1.0553593869 -0.076468904
## 127 4.358897 -0.557778901 -0.035239520 -0.422374423 1.2975113241 0.303781397
## 128 4.115277 -0.558521140 0.190133723 -0.942354331 -0.6148018790 -0.128971629
## 129 4.192704 -0.550471305 0.025208189 -1.306090287 -1.2937417390 -0.062544600
## 130 5.657555 17.808560618 0.477465033 0.304297001 -0.0843429154 0.161294839
## 131 4.080855 -0.541274173 0.086051618 -1.328942623 -1.1933250664 -0.014398907
## 132 4.281290 -0.513731107 -0.020790061 -0.608341291 2.1700397279 0.474867466
## 133 3.911663 -0.565969857 0.298138921 -0.693942269 -0.4018360417 -0.111883212
## 134 4.076209 -0.601379076 0.098123137 -0.657686915 -1.2527572917 -0.055478495
## 135 4.370182 -0.570038671 -0.146443111 -0.279003957 1.2574857905 0.333725527
## 136 4.141673 -0.580054572 0.071748564 -0.731232344 -0.8446230561 -0.108988458
## 137 4.465129 -0.499210955 -0.143970201 -0.308063711 3.5896545461 0.479321310
## 138 3.941137 -0.515513327 0.366475511 -0.974947978 0.3325162914 -0.309259662
## 139 4.015675 -0.527309642 0.245926779 -1.268245625 -0.7231462692 -0.212665855
## 140 4.081901 -0.543474533 0.022119995 -1.305425204 -1.3172215276 -0.058421523
## 141 4.278836 -0.546564230 -0.091458324 -0.806849418 0.4022177115 0.287664530
## 142 4.178837 -0.592087558 -0.190959261 -0.815711351 -1.3220649303 0.056234171
## 143 4.385965 -0.570624662 -0.266855630 -0.344284803 0.9703701224 0.353858783
## 144 4.234685 -0.589468591 -0.090306313 -0.698652911 -0.9037843810 -0.071911290
## 145 4.494812 -0.520085135 -0.231982492 -0.370515432 2.7424996286 0.395845898
## 146 4.036907 -0.523796205 0.166062536 -0.970228645 0.1164985747 -0.253640963
## 147 4.110089 -0.527533235 0.044372089 -1.276306251 -0.7071215722 -0.198662142
## 148 4.184155 -0.540878436 -0.108825209 -1.374870612 -1.2986229885 -0.070580297
## 149 4.326515 -0.535469292 -0.185451029 -0.967426818 0.3400295465 0.245169107
## 150 4.201826 -0.577826999 -0.200938328 -0.990109875 -1.3012920007 0.041156264
## 151 4.375371 -0.563053651 -0.234145653 -0.479923085 0.8601544862 0.341735167
## 152 4.207460 -0.591212230 -0.035685517 -0.701142645 -0.9715145095 -0.046079084
## 153 4.467728 -0.532771038 -0.217046612 -0.273711487 2.5285312916 0.406591475
## 154 4.075212 -0.543765298 0.151678745 -0.828788691 -0.1075174208 -0.222980219
## 155 4.168482 -0.543551827 0.034968032 -1.177547117 -0.9158571419 -0.169731703
## 156 4.354285 -0.505186156 -0.139618511 -0.938650958 1.3672028144 0.240108460
## 157 4.079975 -0.529945885 0.095104150 -1.182496136 -0.5128153758 -0.131392477
## 158 4.137376 -0.552369048 -0.027358097 -1.203650087 -1.2283853894 -0.040071793
## 159 4.304495 -0.550470569 -0.058171885 -0.784056843 0.3957293001 0.261161212
## 160 4.175476 -0.582474629 0.031840751 -0.881778517 -1.1757809018 -0.010018319
## 161 4.393378 -0.547870249 -0.081561865 -0.331641437 1.8137104340 0.411339781
## 162 4.115755 -0.575453597 0.211160066 -0.683202066 -0.5437438010 -0.139854124
## 163 4.204848 -0.575706760 0.042253610 -0.940041812 -1.2748175464 -0.092127927
## 164 4.432548 -0.537152525 -0.048933472 -0.793728979 0.8632512738 0.253613410
## 165 4.175087 -0.543076234 0.117110268 -1.190722087 -0.9267295768 -0.105874339
## 166 4.423403 -0.491736077 0.001766249 -0.667460797 2.8014462846 0.426730508
## 167 3.968686 -0.529941981 0.449891062 -0.967426556 0.0589650361 -0.221993611
## 168 4.023096 -0.555372404 0.306905472 -0.999291424 -0.8691330418 -0.142217766
## 169 4.287570 -0.539530178 0.094452601 -0.442260818 1.6957662767 0.320455517
## 170 4.068272 -0.575427324 0.312208823 -0.631456930 -0.3580744986 -0.135513418
## 171 4.192006 -0.586042183 0.144045791 -0.795182082 -1.0778518132 -0.088896565
## 172 4.413512 -0.552747469 -0.018088924 -0.643966321 0.7673005903 0.221395473
## 173 4.208707 -0.554918395 0.121896431 -1.036425454 -0.8079946766 -0.102728819
## 174 4.410619 -0.501546631 -0.002034479 -0.701037897 2.2526958673 0.346828785
## 175 4.052751 -0.527121133 0.338878038 -1.062133643 -0.0790262375 -0.200285661
## 176 4.098328 -0.543797662 0.193500559 -1.160930443 -0.9004332873 -0.122771688
## 177 4.297118 -0.531236746 0.010933110 -0.719595044 1.0924263428 0.258816223
## 178 4.129527 -0.571246824 0.175624805 -0.804816410 -0.6901555273 -0.085208469
## 179 4.267611 -0.591553698 -0.033769039 -0.844225015 -1.3306291396 -0.029231745
## 180 4.429369 -0.568922662 -0.135083609 -0.663582234 0.0646072566 0.209899224
## 181 4.363866 -0.578509384 -0.189920278 -1.030613106 -1.4359668580 -0.014641814
## 182 4.507961 -0.534504146 -0.178627721 -0.875126371 0.6658822115 0.268429030
## 183 4.263613 -0.542734517 -0.025775522 -1.240011266 -1.0480677842 -0.091677309
## 184 4.515333 -0.499229387 -0.137157847 -0.749978530 2.3178415098 0.389876230
## 185 4.064551 -0.535186198 0.261772888 -1.011628320 -0.3527672873 -0.191651856
## 186 4.155841 -0.564363147 0.115685956 -1.019007613 -1.1987775403 -0.108475203
## 187 4.422828 -0.547547138 -0.097825718 -0.581585260 1.0541610333 0.274330614
## 188 4.210759 -0.573441892 0.054438045 -0.817132538 -0.8993624400 -0.111004897
## 189 4.561851 -0.520163146 -0.142460397 -0.302130214 2.9504673453 0.428421960
## 190 5.415298 17.322141105 0.790819399 0.628191237 -0.4591169273 -0.365370091
## 191 4.189848 -0.546577799 0.125846642 -1.095311060 -0.8641537941 -0.213440335
## 192 4.426068 -0.509125262 -0.067777775 -0.787255035 1.6640608119 0.248919868
## 193 4.128656 -0.536649717 0.215678393 -1.060777486 -0.4450446984 -0.174491622
## 194 4.229230 -0.559420789 0.032342447 -1.106356224 -1.1756487978 -0.096456051
## 195 4.437299 -0.550092105 -0.079596760 -0.743506328 0.5397889742 0.223084354
## 196 4.253369 -0.572744573 0.013759724 -0.912040448 -1.0988629067 -0.069708631
## 197 4.550876 -0.535312123 -0.135916184 -0.445822966 1.9928597594 0.365723327
## 198 4.198374 -0.553968641 0.131237893 -0.856716898 -0.4490502717 -0.202261618
## 199 4.328700 -0.561245768 -0.034327678 -1.129664180 -1.2520544088 -0.146155613
## 200 5.834413 17.264789421 0.307906691 0.502534452 0.2870101265 0.121819559
## Dim.7 Dim.8
## 1 -0.512341670 -0.159510911
## 2 -1.233521086 1.216673431
## 3 -1.783884324 1.869661449
## 4 -1.678513687 1.824872445
## 5 -1.317326271 1.625845794
## 6 -0.663105708 0.835353941
## 7 -0.259803353 0.341366042
## 8 0.101704073 -0.154666381
## 9 -0.272735514 -0.156373108
## 10 -0.139337480 -0.482507410
## 11 0.240873561 -0.837703939
## 12 -0.101605233 -0.540215753
## 13 -0.489617282 -0.131702082
## 14 -0.738075758 0.204107470
## 15 -0.729341046 0.312986504
## 16 -0.497077513 0.150665233
## 17 -0.152018196 -0.199635525
## 18 0.106654892 -0.524513935
## 19 0.119111770 -0.627922594
## 20 -0.078573865 -0.479621377
## 21 -0.350838125 -0.589515498
## 22 -0.605303915 -0.215573052
## 23 -0.667197578 -0.056739996
## 24 -0.479991281 -0.152077212
## 25 -0.118399831 -0.421023629
## 26 0.964517740 -1.089149462
## 27 1.041118178 -1.214769275
## 28 0.868998342 -1.031346612
## 29 0.558851977 -0.704604959
## 30 0.262074803 -0.410525139
## 31 0.185879976 -0.258607464
## 32 0.327476139 -0.269103620
## 33 0.575054602 -0.454977639
## 34 0.835557174 -0.751492548
## 35 0.897243896 -0.951122433
## 36 0.811775864 -0.951175450
## 37 0.550027750 -0.741882121
## 38 0.248345633 -0.472351813
## 39 0.135310824 -0.289330962
## 40 0.144704203 -0.161650556
## 41 0.459549541 0.016713531
## 42 0.721620486 -0.094176109
## 43 0.900691572 -0.281298076
## 44 0.955464179 -0.322891591
## 45 0.904299814 -0.189311679
## 46 0.729477497 -0.006881108
## 47 0.549137208 0.275488125
## 48 0.405564224 0.534730004
## 49 0.366462868 0.773913189
## 50 0.411963139 0.836234050
## 51 0.511193185 0.794347345
## 52 0.632585659 0.694860606
## 53 0.674189441 0.561604947
## 54 0.683569181 0.522762117
## 55 0.568905722 0.600262917
## 56 0.398206730 0.646125779
## 57 0.108462823 0.538869962
## 58 -0.099494142 0.459869967
## 59 -0.250390211 0.479608418
## 60 -0.596434967 0.775977731
## 61 -0.622164872 0.513051202
## 62 -0.671262330 0.663249530
## 63 -0.658061077 0.504336247
## 64 0.119938322 0.420283049
## 65 2.781720112 1.867213266
## 66 2.259971721 0.306351957
## 67 1.629515194 -0.556675229
## 68 0.818855906 -0.779968185
## 69 -0.063286732 -0.616876940
## 70 -0.773739671 -0.262495298
## 71 -0.757170575 0.403545290
## 72 0.711794108 1.848678669
## 73 0.507448622 0.975090088
## 74 0.640040807 0.144748905
## 75 0.777868669 -0.523576648
## 76 0.731699724 -0.875282135
## 77 0.476388102 -0.898556411
## 78 0.031594634 -0.623294219
## 79 -0.351552876 -0.301228903
## 80 -0.510757362 -0.128811441
## 81 -0.612740380 -0.828218053
## 82 -0.077875164 -0.789001545
## 83 0.077063888 -0.577255220
## 84 -0.072560389 -0.259323635
## 85 -0.329290927 0.104244148
## 86 -0.574836953 0.403379598
## 87 -0.782152590 0.498465803
## 88 -0.851856054 0.447494133
## 89 -0.759419555 0.307705299
## 90 -0.639308128 0.131190193
## 91 -0.446311897 -0.107640662
## 92 -0.288598597 -0.310311059
## 93 -0.288970135 -0.418709183
## 94 -0.439696786 -0.461335460
## 95 -0.719453307 -0.470109729
## 96 -1.037286884 -0.441940996
## 97 -1.247475297 -0.435638913
## 98 -1.397573959 -0.433764741
## 99 -1.390421467 -0.426948967
## 100 -1.255156483 -0.446782048
## 101 -0.887407498 -1.333803240
## 102 -0.343578576 -0.967500126
## 103 -0.610968525 -1.015622968
## 104 0.323247868 0.053429062
## 105 -0.239825426 -0.481512107
## 106 -0.526441664 -0.768807994
## 107 -0.030910375 -0.222885733
## 108 -0.100729955 -0.341771773
## 109 0.995804236 0.825292330
## 110 0.429118087 0.212034824
## 111 0.404307704 0.364232503
## 112 0.474232268 -0.353884958
## 113 0.846421611 -0.714058242
## 114 1.138264423 -1.130184410
## 115 0.066934856 0.151703040
## 116 0.114820366 -0.161841113
## 117 1.145994255 0.673654578
## 118 0.682638054 -0.081279629
## 119 0.274597109 -0.518238543
## 120 0.578865365 0.205349088
## 121 -0.229603761 -0.049062318
## 122 -0.708200560 -0.075177080
## 123 -0.519014277 0.447263853
## 124 -0.680848129 0.352825110
## 125 0.282728283 1.153121839
## 126 0.022499536 0.393866478
## 127 -0.053072875 -0.244175362
## 128 0.608482094 0.035137352
## 129 0.164191152 -0.554219059
## 130 -0.253355274 -0.788071219
## 131 -0.197367960 -0.212041641
## 132 -0.530606372 -0.070597023
## 133 0.152170216 1.004298802
## 134 -0.286565777 0.501736959
## 135 -0.356187352 0.012591244
## 136 0.322749117 0.226096128
## 137 0.347744730 -0.210451747
## 138 1.462421548 0.842370437
## 139 0.693439150 0.248920601
## 140 -0.149815924 -0.128385221
## 141 -0.650802680 -0.190603071
## 142 -0.698471415 0.037960806
## 143 -0.613889330 -0.075086459
## 144 0.100342799 0.164951260
## 145 0.217928208 -0.232696208
## 146 1.181706360 0.585073446
## 147 0.658905193 0.108735750
## 148 -0.075705565 -0.260885535
## 149 -0.527811658 -0.281523786
## 150 -0.663957925 -0.037045029
## 151 -0.706556231 -0.055588612
## 152 -0.150290736 0.258973427
## 153 -0.053242795 -0.062248134
## 154 0.905934091 0.616775624
## 155 0.473524258 -0.010828287
## 156 0.043801975 -0.320031348
## 157 0.311419070 0.304951720
## 158 -0.343186629 0.011768540
## 159 -0.686679687 -0.093361465
## 160 -0.481868930 0.196811584
## 161 -0.553398340 0.023163537
## 162 0.289653633 0.602768591
## 163 -0.029087034 -0.048171722
## 164 -0.173586410 -0.508600662
## 165 0.192468033 -0.126814541
## 166 -0.057980593 -0.240710385
## 167 0.711771388 0.908506729
## 168 0.040103803 0.548835704
## 169 -0.412802114 0.255671960
## 170 0.203068505 0.809602486
## 171 -0.102927616 0.201285785
## 172 -0.222521082 -0.279901108
## 173 0.188357473 -0.062633164
## 174 -0.006826831 -0.295023927
## 175 0.654317366 0.569555814
## 176 0.017478135 0.233284383
## 177 -0.452931023 0.056987093
## 178 -0.136767142 0.534553947
## 179 -0.491993516 0.053636550
## 180 -0.565823514 -0.305561517
## 181 -0.390256236 -0.452667983
## 182 -0.357627992 -0.674751948
## 183 0.028388888 -0.253930227
## 184 -0.196198269 -0.334281663
## 185 0.400154381 0.685441082
## 186 -0.230823368 0.283254852
## 187 -0.512240759 -0.003781957
## 188 -0.065681838 0.370969516
## 189 -0.124693050 -0.007924483
## 190 0.851771560 0.883539497
## 191 0.405967388 0.254202920
## 192 -0.053125378 -0.161044730
## 193 0.328886854 0.456937380
## 194 -0.244147048 0.086110183
## 195 -0.561209480 -0.144014619
## 196 -0.308794518 0.150441856
## 197 -0.365057763 -0.120331760
## 198 0.443562955 0.551568781
## 199 0.027729421 -0.091650217
## 200 -0.322064983 -0.4372107128 Plotting PCA
The Biplot also have another way for visualization by using plot.PCA. Plot PCA shows the group of data and outliers.
plot.PCA(
x = Penicillin_pca, # object pca
choix = "ind", # pilihan, untuk menampilkan plot individual
)
plot.PCA(
x = Penicillin_pca,
choix = "var"
)## Warning: ggrepel: 28 unlabeled data points (too many overlaps). Consider
## increasing max.overlaps
Also, another way to check which variable have significant impact by using function dimdesc. The correlation value list the rangking of significant variables.
Penicillin_dim <- dimdesc(Penicillin_pca)
Penicillin_dim$Dim.1$quanti %>% as.data.frame()## correlation
## X2.PAT.control.PAT_ref.PAT.ref. 0.9955172
## X1.Raman.spec.recorded 0.9955172
## Water.for.injection.dilution.Fw.L.h. 0.9955172
## Batch.reference.Batch_ref.Batch.ref. 0.9955172
## Substrate.concentration.S.g.L. 0.9946835
## Penicillin.concentration.P.g.L. 0.9942874
## Time..h. 0.9924983
## Vessel.Weight.Wt.Kg. 0.9854959
## Vessel.Volume.V.L. 0.9803943
## Carbon.evolution.rate.CER.g.h. 0.9791001
## Generated.heat.Q.kJ. 0.9628192
## Air.head.pressure.pressure.bar. 0.9625981
## carbon.dioxide.percent.in.off.gas.CO2outgas... 0.9589103
## Aeration.rate.Fg.L.h. 0.9425874
## Batch.ID 0.9360245
## Fault.flag 0.9356546
## Sugar.feed.rate.Fs.L.h. 0.8190677
## PAA.flow.Fpaa.PAA.flow..L.h.. 0.7054024
## Heating.water.flow.rate.Fh.L.h. 0.4733881
## Oxygen.in.percent.in.off.gas.O2.O2...... 0.4370433
## pH.pH.pH. 0.2084972
## Acid.flow.rate.Fa.L.h. 0.1972050
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 0.1593926
## Viscosity.Viscosity_offline.centPoise. 0.1539052
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 0.1500103
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 0.1429271
## Dumped.broth.flow.Fremoved.L.h. -0.2535978
## Oxygen.Uptake.Rate.OUR..g.min...1... -0.4397498
## Temperature.T.K. -0.5275643
## Heating.cooling.water.flow.rate.Fc.L.h. -0.5782750
## Base.flow.rate.Fb.L.h. -0.7336845
## Oil.flow.Foil.L.hr. -0.7625361
## p.value
## X2.PAT.control.PAT_ref.PAT.ref. 9.195904e-205
## X1.Raman.spec.recorded 9.195904e-205
## Water.for.injection.dilution.Fw.L.h. 9.195904e-205
## Batch.reference.Batch_ref.Batch.ref. 9.195904e-205
## Substrate.concentration.S.g.L. 1.904695e-197
## Penicillin.concentration.P.g.L. 2.295776e-194
## Time..h. 1.090146e-182
## Vessel.Weight.Wt.Kg. 1.721819e-154
## Vessel.Volume.V.L. 1.218374e-141
## Carbon.evolution.rate.CER.g.h. 6.407187e-139
## Generated.heat.Q.kJ. 1.682780e-114
## Air.head.pressure.pressure.bar. 2.993402e-114
## carbon.dioxide.percent.in.off.gas.CO2outgas... 2.754635e-110
## Aeration.rate.Fg.L.h. 2.950028e-96
## Batch.ID 9.571644e-92
## Fault.flag 1.662867e-91
## Sugar.feed.rate.Fs.L.h. 1.142356e-49
## PAA.flow.Fpaa.PAA.flow..L.h.. 2.027695e-31
## Heating.water.flow.rate.Fh.L.h. 1.450763e-12
## Oxygen.in.percent.in.off.gas.O2.O2...... 9.779517e-11
## pH.pH.pH. 3.049095e-03
## Acid.flow.rate.Fa.L.h. 5.126765e-03
## Offline.Penicillin.concentration.P_offline.P.g.L...1... 2.416756e-02
## Viscosity.Viscosity_offline.centPoise. 2.956376e-02
## Offline.Biomass.concentratio.X_offline.X.g.L...1... 3.399086e-02
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... 4.348698e-02
## Dumped.broth.flow.Fremoved.L.h. 2.908149e-04
## Oxygen.Uptake.Rate.OUR..g.min...1... 7.268698e-11
## Temperature.T.K. 1.002775e-15
## Heating.cooling.water.flow.rate.Fc.L.h. 3.052754e-19
## Base.flow.rate.Fb.L.h. 4.549809e-35
## Oil.flow.Foil.L.hr. 2.636817e-399 Contribution of each variables
fviz_contrib(X = Penicillin_pca,
choice = "var",
axes = 1)
summary(Penicillin_pca)##
## Call:
## PCA(X = Penicillin_clean, scale.unit = T, ncp = 8, graph = F)
##
##
## Eigenvalues
## Dim.1 Dim.2 Dim.3 Dim.4 Dim.5 Dim.6 Dim.7
## Variance 18.998 4.863 4.411 2.011 1.361 0.654 0.423
## % of var. 55.877 14.304 12.972 5.915 4.003 1.923 1.243
## Cumulative % of var. 55.877 70.181 83.153 89.068 93.072 94.995 96.238
## Dim.8 Dim.9 Dim.10 Dim.11 Dim.12 Dim.13 Dim.14
## Variance 0.335 0.253 0.189 0.127 0.112 0.074 0.060
## % of var. 0.984 0.744 0.557 0.374 0.330 0.216 0.176
## Cumulative % of var. 97.222 97.965 98.522 98.896 99.226 99.443 99.619
## Dim.15 Dim.16 Dim.17 Dim.18 Dim.19 Dim.20 Dim.21
## Variance 0.044 0.037 0.019 0.019 0.005 0.002 0.001
## % of var. 0.129 0.110 0.056 0.055 0.014 0.005 0.003
## Cumulative % of var. 99.748 99.858 99.914 99.969 99.983 99.988 99.991
## Dim.22 Dim.23 Dim.24 Dim.25 Dim.26 Dim.27 Dim.28
## Variance 0.001 0.001 0.001 0.000 0.000 0.000 0.000
## % of var. 0.003 0.003 0.002 0.001 0.001 0.000 0.000
## Cumulative % of var. 99.995 99.997 99.999 99.999 100.000 100.000 100.000
## Dim.29 Dim.30 Dim.31 Dim.32 Dim.33 Dim.34
## Variance 0.000 0.000 0.000 0.000 0.000 0.000
## % of var. 0.000 0.000 0.000 0.000 0.000 0.000
## Cumulative % of var. 100.000 100.000 100.000 100.000 100.000 100.000
##
## Individuals (the 10 first)
## Dist Dim.1
## 1 | 6.917 | -4.869
## 2 | 6.877 | -4.580
## 3 | 7.141 | -4.385
## 4 | 7.242 | -4.118
## 5 | 8.065 | -3.721
## 6 | 7.201 | -3.768
## 7 | 7.152 | -3.719
## 8 | 7.191 | -3.700
## 9 | 6.762 | -3.841
## 10 | 6.778 | -3.871
## ctr cos2 Dim.2
## 1 0.624 0.496 | 0.287
## 2 0.552 0.444 | 0.217
## 3 0.506 0.377 | 0.120
## 4 0.446 0.323 | 0.045
## 5 0.364 0.213 | 2.391
## 6 0.374 0.274 | -0.019
## 7 0.364 0.270 | -0.012
## 8 0.360 0.265 | 0.003
## 9 0.388 0.323 | 0.155
## 10 0.394 0.326 | 0.196
## ctr cos2 Dim.3
## 1 0.008 0.002 | -3.175
## 2 0.005 0.001 | -4.433
## 3 0.001 0.000 | -4.860
## 4 0.000 0.000 | -5.164
## 5 0.588 0.088 | -5.350
## 6 0.000 0.000 | -5.489
## 7 0.000 0.000 | -5.502
## 8 0.000 0.000 | -5.470
## 9 0.002 0.001 | -5.281
## 10 0.004 0.001 | -5.196
## ctr cos2
## 1 1.143 0.211 |
## 2 2.228 0.416 |
## 3 2.678 0.463 |
## 4 3.024 0.508 |
## 5 3.245 0.440 |
## 6 3.415 0.581 |
## 7 3.432 0.592 |
## 8 3.392 0.579 |
## 9 3.162 0.610 |
## 10 3.061 0.588 |
##
## Variables (the 10 first)
## Dim.1 ctr cos2
## Time..h. | 0.992 5.185 0.985
## Aeration.rate.Fg.L.h. | 0.943 4.677 0.888
## Sugar.feed.rate.Fs.L.h. | 0.819 3.531 0.671
## Acid.flow.rate.Fa.L.h. | 0.197 0.205 0.039
## Base.flow.rate.Fb.L.h. | -0.734 2.833 0.538
## Heating.cooling.water.flow.rate.Fc.L.h. | -0.578 1.760 0.334
## Heating.water.flow.rate.Fh.L.h. | 0.473 1.180 0.224
## Water.for.injection.dilution.Fw.L.h. | 0.996 5.217 0.991
## Air.head.pressure.pressure.bar. | 0.963 4.877 0.927
## Dumped.broth.flow.Fremoved.L.h. | -0.254 0.339 0.064
## Dim.2 ctr cos2
## Time..h. | -0.030 0.018 0.001
## Aeration.rate.Fg.L.h. | -0.039 0.031 0.001
## Sugar.feed.rate.Fs.L.h. | -0.047 0.046 0.002
## Acid.flow.rate.Fa.L.h. | -0.097 0.193 0.009
## Base.flow.rate.Fb.L.h. | 0.014 0.004 0.000
## Heating.cooling.water.flow.rate.Fc.L.h. | 0.007 0.001 0.000
## Heating.water.flow.rate.Fh.L.h. | 0.020 0.008 0.000
## Water.for.injection.dilution.Fw.L.h. | -0.035 0.026 0.001
## Air.head.pressure.pressure.bar. | -0.042 0.036 0.002
## Dumped.broth.flow.Fremoved.L.h. | 0.109 0.246 0.012
## Dim.3 ctr cos2
## Time..h. | 0.087 0.171 0.008
## Aeration.rate.Fg.L.h. | 0.286 1.858 0.082
## Sugar.feed.rate.Fs.L.h. | 0.470 5.006 0.221
## Acid.flow.rate.Fa.L.h. | -0.084 0.160 0.007
## Base.flow.rate.Fb.L.h. | 0.448 4.546 0.201
## Heating.cooling.water.flow.rate.Fc.L.h. | 0.670 10.167 0.448
## Heating.water.flow.rate.Fh.L.h. | 0.006 0.001 0.000
## Water.for.injection.dilution.Fw.L.h. | 0.052 0.061 0.003
## Air.head.pressure.pressure.bar. | 0.209 0.991 0.044
## Dumped.broth.flow.Fremoved.L.h. | -0.056 0.070 0.003
##
## Time..h. |
## Aeration.rate.Fg.L.h. |
## Sugar.feed.rate.Fs.L.h. |
## Acid.flow.rate.Fa.L.h. |
## Base.flow.rate.Fb.L.h. |
## Heating.cooling.water.flow.rate.Fc.L.h. |
## Heating.water.flow.rate.Fh.L.h. |
## Water.for.injection.dilution.Fw.L.h. |
## Air.head.pressure.pressure.bar. |
## Dumped.broth.flow.Fremoved.L.h. |Penicillin_pca$eig## eigenvalue percentage of variance cumulative percentage of variance
## comp 1 1.899815e+01 5.587690e+01 55.87690
## comp 2 4.863329e+00 1.430391e+01 70.18081
## comp 3 4.410565e+00 1.297225e+01 83.15306
## comp 4 2.011128e+00 5.915082e+00 89.06814
## comp 5 1.361185e+00 4.003486e+00 93.07163
## comp 6 6.538093e-01 1.922968e+00 94.99459
## comp 7 4.225952e-01 1.242927e+00 96.23752
## comp 8 3.346009e-01 9.841203e-01 97.22164
## comp 9 2.528977e-01 7.438169e-01 97.96546
## comp 10 1.892245e-01 5.565428e-01 98.52200
## comp 11 1.272423e-01 3.742420e-01 98.89624
## comp 12 1.122522e-01 3.301534e-01 99.22640
## comp 13 7.358924e-02 2.164390e-01 99.44284
## comp 14 5.991706e-02 1.762266e-01 99.61906
## comp 15 4.372847e-02 1.286131e-01 99.74767
## comp 16 3.741396e-02 1.100411e-01 99.85772
## comp 17 1.909417e-02 5.615934e-02 99.91388
## comp 18 1.867559e-02 5.492821e-02 99.96880
## comp 19 4.835394e-03 1.422175e-02 99.98303
## comp 20 1.717949e-03 5.052792e-03 99.98808
## comp 21 1.134510e-03 3.336795e-03 99.99141
## comp 22 1.049859e-03 3.087821e-03 99.99450
## comp 23 8.975892e-04 2.639968e-03 99.99714
## comp 24 5.343709e-04 1.571679e-03 99.99871
## comp 25 2.391284e-04 7.033187e-04 99.99942
## comp 26 1.860244e-04 5.471304e-04 99.99996
## comp 27 9.102565e-06 2.677225e-05 99.99999
## comp 28 2.266718e-06 6.666818e-06 100.00000
## comp 29 6.112465e-07 1.797784e-06 100.00000
## comp 30 2.879639e-09 8.469526e-09 100.00000
## comp 31 1.870981e-10 5.502886e-10 100.00000
## comp 32 5.583299e-31 1.642147e-30 100.00000
## comp 33 1.773000e-31 5.214707e-31 100.00000
## comp 34 5.630238e-32 1.655952e-31 100.00000Penicillin_keep <- Penicillin_pca$ind$coord[,1:5] %>%
as.data.frame()
Penicillin_keep %>% head()## Dim.1 Dim.2 Dim.3 Dim.4 Dim.5
## 1 -4.869169 0.28675711 -3.175056 -1.0892563 0.99854214
## 2 -4.580076 0.21664951 -4.432756 -0.3991510 0.51718424
## 3 -4.385247 0.11995016 -4.860014 0.5602269 0.20430577
## 4 -4.118362 0.04486635 -5.164468 1.2732793 -0.07875848
## 5 -3.720834 2.39149583 -5.350491 2.0468900 -0.44743383
## 6 -3.767883 -0.01948551 -5.488533 1.9402648 -0.50970545# reconstruct data PC1 - PC5
Penicillin_reconst <- reconst(Penicillin_pca,
ncp = 34)
head(data.frame(Penicillin_reconst), 3)## Time..h. Aeration.rate.Fg.L.h. Sugar.feed.rate.Fs.L.h.
## 1 -14.092285 29.13081 7.905378
## 2 -7.151143 29.40315 2.438596
## 3 -4.335031 29.72706 2.647362
## Acid.flow.rate.Fa.L.h. Base.flow.rate.Fb.L.h.
## 1 -0.6760913 30.36147
## 2 -0.5470397 40.70391
## 3 -0.2034562 47.39887
## Heating.cooling.water.flow.rate.Fc.L.h. Heating.water.flow.rate.Fh.L.h.
## 1 22.43190 25.867436
## 2 18.16832 10.449894
## 3 13.79194 5.397766
## Water.for.injection.dilution.Fw.L.h. Air.head.pressure.pressure.bar.
## 1 -24.960815 0.5836014
## 2 -13.998870 0.5794435
## 3 -8.747638 0.5806842
## Dumped.broth.flow.Fremoved.L.h. Substrate.concentration.S.g.L.
## 1 483.8761 -4.8555578
## 2 483.9234 -1.7840465
## 3 216.9242 -0.6765232
## Dissolved.oxygen.concentration.DO2.mg.L. Penicillin.concentration.P.g.L.
## 1 14.17876 -0.6926179
## 2 14.52519 -0.4494474
## 3 14.59292 -0.2943982
## Vessel.Volume.V.L. Vessel.Weight.Wt.Kg. pH.pH.pH. Temperature.T.K.
## 1 57766.61 61498.92 6.484773 298.1325
## 2 58192.76 62068.62 6.521536 298.1310
## 3 58311.74 62259.65 6.552147 298.1255
## Generated.heat.Q.kJ. carbon.dioxide.percent.in.off.gas.CO2outgas...
## 1 -1.925479 0.08129982
## 2 -2.972295 0.05200333
## 3 -3.720737 0.05765899
## PAA.flow.Fpaa.PAA.flow..L.h..
## 1 2.983965
## 2 4.754315
## 3 5.664836
## PAA.concentration.offline.PAA_offline.PAA..g.L...1... Oil.flow.Foil.L.hr.
## 1 19.62366 26.26394
## 2 39.06389 23.04186
## 3 50.09825 21.67831
## NH_3.concentration.off.line.NH3_offline.NH3..g.L...1...
## 1 35.71872
## 2 119.62714
## 3 168.35982
## Oxygen.Uptake.Rate.OUR..g.min...1... Oxygen.in.percent.in.off.gas.O2.O2......
## 1 0.193232417 0.2015992
## 2 0.040894075 0.2042091
## 3 0.002923577 0.2050455
## Offline.Penicillin.concentration.P_offline.P.g.L...1...
## 1 -0.01293145
## 2 -0.08408262
## 3 -0.12490274
## Offline.Biomass.concentratio.X_offline.X.g.L...1...
## 1 -0.02410792
## 2 -0.14573600
## 3 -0.21441951
## Carbon.evolution.rate.CER.g.h. Viscosity.Viscosity_offline.centPoise.
## 1 -0.0147559506 -0.181744
## 2 -0.0131815570 -1.067650
## 3 0.0001921265 -1.585490
## X1.Raman.spec.recorded X2.PAT.control.PAT_ref.PAT.ref.
## 1 -8.884483 -8.884483
## 2 -4.543553 -4.543553
## 3 -2.464064 -2.464064
## Batch.reference.Batch_ref.Batch.ref. Batch.ID Fault.flag
## 1 -0.09984326 12555.386 12549.72
## 2 -0.05599548 7339.345 7362.67
## 3 -0.03499055 4602.015 4636.9710 Conclusion
- The PCA analysis of Bioreactors for Penicillin production was successfully conducted.
- The imprtant PC to keep 90% information is PC1 to PC5.
- Most significant variable is “X2.PAT.control.PAT_ref.PAT.ref.” and less significant variable is “Oil.flow.Foil.L.hr.”.