Reproductive number of mumps among children in France is 12.00 (Kitala et al, 2002)
Ro = 12.00
Generate sequence of numbers for fraction of population vaccinated from 0 to 1 with 0.1 interval
fraction_vaccinated_mumps = seq (0, 1, 0.1)
Print fraction of population vaccinated.
cat ("Fraction of population vaccinated: ", fraction_vaccinated_mumps)
## Fraction of population vaccinated: 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1
Compute effective reproductive number
Re = Ro * (1 - fraction_vaccinated_mumps)
Print effective reproductive number
cat ("Effective reproductive number:", Re)
## Effective reproductive number: 12 10.8 9.6 8.4 7.2 6 4.8 3.6 2.4 1.2 0
Compute herd immunity threshold
herd_immunity_threshold = 1 - (1/Ro)
Print herd immunity threshold
cat ("herd immunity threshold = ", herd_immunity_threshold)
## herd immunity threshold = 0.9166667
Plot fraction of population vaccinated (versus) effective reproductive number
subtitle = paste ("Ro = ", Ro, ", herd immunity threshold = ", round (herd_immunity_threshold, digits = 4), "; children (France) - Kitala et al (2002)", sep="")
plot (fraction_vaccinated_mumps, Re, main = "Mumps" , sub = subtitle, xlab = "Fraction of Population Vaccinated \n", ylab = "Effective Reproductive Number (Re)")
Results and Discussion
Reproductive number of rabies among dogs in Kenya is 12.00 (Kitala et al, 2002). The graph illustrates that as fraction of population vaccinated increases, effective reproductive number decreases. Herd immunity threshold is 91.67%; that is, at this level of vaccination coverage, effective reproductive number is 1 (Re = 1). When vaccination coverage is above 91.67%, effective reproductive number is less than 1 (Re < 1); thereby, mumps will be eliminated at these higher levels of vaccination coverage
Public heath implications
Recommend rubella vaccination among children in Sweden at coverage levels of above 91.67%