The following table summarizes the mean changes of lab values within histotripsy and cryoablation groups (with p-values testing whether the changes are zero) and a between-group test on the difference in the change.

Table 1. Mean changes from Baseline to Day 28 and comparison between histotripsy and cryoablation.
Histotripsy Cryoablation p-value*
Creatinine 0.7 (p<0.001) 0.8 (p<0.001) 0.321
eGFR -5.9 (p=0.157) -1.6 (p=0.835) 0.622
BUN -2.2 (p=0.069) -2.3 (p=0.008) 0.947
Hgb -1.6 (p=0.003) -1.6 (p=0.221) 1
Hct -5.6 (p=0.005) -5.9 (p=0.183) 0.951
Na -5 (p<0.001) -5 (p<0.001) 1
K -0.6 (p<0.001) -0.5 (p=0.013) 0.709
Cl -1.1 (p=0.057) -1.4 (p=0.042) 0.739
HCO3 0.7 (p=0.563) -0.6 (p=0.531) 0.399

*Between-group test