Exploring the Similarities in Parent-Child Perceptions of Drug Use Risk: The Role of Genetics and Environment

Francisco Cardozo, Ph.D. Student

Division of Prevention Science and Community Health

Department of Public Health Sciences

Miller School of Medicine

University of Miami

Tuesday, 21th March, 2023

Coauthors

Coauthors

  • Dr. Juliana Mejía-Trujillo, MA; Director of Community Prevention, Corporación Nuevos Rumbos (Bogotá, Colombia).

  • Dr. Augusto Pérez-Gómez, PhD; Founding Director, Corporación Nuevos Rumbos (Bogotá, Colombia).

  • Dr. Eric C. Brown, PhD; Associate Professor. Department of Public Health Sciences, Miller School of Medicine, University of Miami.

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Background

Background

  • Drug prevention programs often assume shared parent-child perceptions of drug use risk factors.

  • Factors influencing perceptions of risk:

    • Cultural factors: varying perspectives on drug acceptability and dangers.
    • Experiential factors: personal or family history of drug use.
    • Genetic factors: predispositions affecting substance use disorder likelihood and risk perception.

Based on these assumptions, we develop prevention programs that modify parents’ behaviors, with the hope that these changes will align with the perceptions of their children.

How accurate is the assumption?

To what extent can we rely on it?

Objective

Objective


To determine the extent to which genetic and environmental factors influence perceptions of drug risk among youth and their parents, and whether these factors differ between same-sex and different-sex dyads.

Methods

Methods

Participants

  • N = 194 parent-student dyads from a public school in Bogotá, Colombia.
  • Students’ age: M = 15.4 years (SD = 1.30 ); Parents’ age: M = 41.9 years (SD = 9.11 ).

Data Collection Procedures

  • Parents invited to participate via letter with consent form, survey, and return envelope.
  • Parents completed survey and returned it via regular mail.
  • Students of participating parents completed survey individually during school hours.
  • Student survey linked to parent survey via ID.

Bogotá, Colombia

Measure

  • Parent-Youth Risk and Protective Factor Survey, adapted from Communities That Care Youth Survey. (Arthur et al. 2007)

  • Focus on risk perception of drug use

How much do you think people risk harming themselves (physically or in other ways) if they…

  • …smoke one or more packs of cigarettes per day?
  • …try marijuana once or twice?
  • …smoke marijuana regularly?
  • …take one or two drinks of an alcoholic beverage (beer, wine, or liquor) nearly every day?

Responses a four-point Likert-type scale: 1=high risk, 2=moderate risk, 3=low risk, 4=no risk.

Statistical Analysis


Multigroup Confirmatory Factor Analyses (MG-CFA) to evaluate parent-child differences in measurement of perceived harms of drug use (Muthén, Asparouhov, et al. 2002).

Estimated ACE Model to assess influence of genetics, common environmental exposure, and unique environmental experiences (Maes 2014).

Decomposes variance into three sources:
- Additive genetic variation or heritability coefficient (A).
- Shared environment (C).
- Nonshared environment (E).

ACE components are latent variables with M = 0 and SD = 1.

ACE Model

Results

Multigroup Confirmatory Factor Analysis:

  • Significant differences between parent and student measurement models; \(\Delta \chi^2\)(4) = 42.232, p < .001.

  • Notable differences in standardized factor loadings for alcohol (\(\Delta \lambda\) = 0.360) and cigarettes (\(\Delta \lambda\) = 0.286) items.

  • No significant differences in standardized factors loadings between same- and different-sex dyads; \(\Delta \chi^2\)(8) = 5.271, p = .728.

Results

ACE Model Analysis:

  • Additive genetic component (A) explained:
    • 13.8% of risk perception variance among different-sex dyads.
    • 22.9% of variance among same-sex dyads.
  • Environmental component (C) explained:
    • 7.0 % of risk perception variance among different-sex dyads.
    • 11.6% of variance among same-sex dyads.
  • Nonshared environment (E) ranged from 65% to 79%.

Limitations

Limitations

  • Sample size was limited.
  • Only one public school.
  • Possible lack of independence in parental responses.

Conclusion

Conclusion

  • Genetics play a notable role in shaping risk perceptions:

    • But only 11.6% to 22.9% of variance explained in risk perception among same-sex dyads.
  • Same-sex dyads were more likely to be similar in terms of their perceptions about drugs.

  • Majority of variance not explained by A and C components of the model, indicating further research is needed to understand other contributing factors.

  • Findings highlight the importance of considering these factors in the design and implementation of drug prevention programs targeting families.

Thank you 🧬 👩‍👦

Francisco Cardozo.
foc9@miami.edu

References

Arthur, Michael, John Briney, J. Hawkins, Robert Abbott, Blair Brooke-Weiss, and Richard Catalano. 2007. “Measuring Risk and Protection in Communities Using the Communities That Care Youth Survey.” Evaluation and Program Planning 30 (June): 197–211. https://doi.org/10.1016/j.evalprogplan.2007.01.009.
Maes, Hermine H. 2014. ACE Model.” In Wiley StatsRef: Statistics Reference Online. John Wiley & Sons, Ltd. https://doi.org/10.1002/9781118445112.stat06752.
Muthén, Bengt, Tihomir Asparouhov, et al. 2002. “Latent Variable Analysis with Categorical Outcomes: Multiple-Group and Growth Modeling in Mplus.” Mplus Web Notes 4 (5): 1–22.