Currate ADNI & BULLET Phantoms
Last Ran: 2023-03-03
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ADNI Phantom
Full dataset
| PRISMA 1 (N=44) |
PRISMA 2 (N=12) |
SKYRA (N=55) |
NUBIC (N=61) |
P-value | |
|---|---|---|---|---|---|
| Year | |||||
| 2018 | 7 (15.9%) | 0 (0%) | 6 (10.9%) | 9 (14.8%) | 0.174 |
| 2019 | 10 (22.7%) | 5 (41.7%) | 16 (29.1%) | 15 (24.6%) | |
| 2020 | 7 (15.9%) | 7 (58.3%) | 10 (18.2%) | 10 (16.4%) | |
| 2021 | 11 (25.0%) | 0 (0%) | 11 (20.0%) | 13 (21.3%) | |
| 2022 | 7 (15.9%) | 0 (0%) | 11 (20.0%) | 12 (19.7%) | |
| 2023 | 2 (4.5%) | 0 (0%) | 1 (1.8%) | 2 (3.3%) | |
| SNR | |||||
| Mean (SD) | 112 (4.09) | 109 (2.54) | 141 (14.0) | 112 (2.64) | <0.001 |
| Median [Min, Max] | 112 [105, 119] | 108 [106, 115] | 143 [67.9, 150] | 112 [106, 118] | |
| SNR_manufacturerZ | |||||
| Mean (SD) | -0.00909 (1.20) | -0.883 (0.748) | 0.00364 (1.00) | 0.182 (0.778) | 0.00872 |
| Median [Min, Max] | 0.0500 [-1.90, 2.30] | -1.10 [-1.80, 0.800] | 0.200 [-5.20, 0.600] | 0.200 [-1.70, 1.70] | |
| SNR_siteZ | |||||
| Mean (SD) | 0.148 (1.03) | -0.592 (0.654) | 0.00364 (1.00) | -0.00492 (1.00) | 0.159 |
| Median [Min, Max] | 0.200 [-1.50, 2.10] | -0.800 [-1.40, 0.900] | 0.200 [-5.20, 0.600] | 0 [-2.40, 2.00] | |
| SNR_ScannerZ | |||||
| Mean (SD) | -0.0000000000000000505 (1.00) | 0.00833 (0.990) | 0.00364 (1.00) | -0.00492 (1.00) | 1 |
| Median [Min, Max] | 0.0500 [-1.60, 1.90] | -0.300 [-1.20, 2.30] | 0.200 [-5.20, 0.600] | 0 [-2.40, 2.00] |
Outlier detection
| Outlier (N=2) |
Within Range (N=170) |
P-value | |
|---|---|---|---|
| ADNI_site_outlier.factor | |||
| Outlier | 2 (100%) | 0 (0%) | <0.001 |
| Within Range | 0 (0%) | 170 (100%) | |
| ADNI_manufacture_outlier.factor | |||
| Outlier | 2 (100%) | 0 (0%) | <0.001 |
| Within Range | 0 (0%) | 170 (100%) | |
| Year | |||
| 2018 | 0 (0%) | 22 (12.9%) | 0.736 |
| 2019 | 1 (50.0%) | 45 (26.5%) | |
| 2020 | 0 (0%) | 34 (20.0%) | |
| 2021 | 0 (0%) | 35 (20.6%) | |
| 2022 | 1 (50.0%) | 29 (17.1%) | |
| 2023 | 0 (0%) | 5 (2.9%) | |
| SCANNER | |||
| PRISMA 1 | 0 (0%) | 44 (25.9%) | 0.23 |
| PRISMA 2 | 0 (0%) | 12 (7.1%) | |
| SKYRA | 2 (100%) | 53 (31.2%) | |
| NUBIC | 0 (0%) | 61 (35.9%) |
Restricted data
- Data restricted to points with no parameter changes and total number of expected volumes, and no outliers (standardized Z score more than 3SDs from mean).
PRISMA |
SKYRA |
Overall |
||
|---|---|---|---|---|
| Within Range (N=117) |
Within Range (N=53) |
Within Range (N=170) |
P-value | |
| SNR | ||||
| Mean (SD) | 112 (3.40) | 143 (3.57) | 122 (15.0) | <0.001 |
| Median [Min, Max] | 112 [105, 119] | 143 [133, 150] | 114 [105, 150] | |
| SNR_ScannerZ | ||||
| Mean (SD) | -0.00171 (0.993) | 0.191 (0.259) | 0.0582 (0.840) | 0.385 |
| Median [Min, Max] | 0 [-2.40, 2.30] | 0.200 [-0.500, 0.600] | 0.200 [-2.40, 2.30] | |
| SNR_siteZ | ||||
| Mean (SD) | -0.00769 (1.00) | 0.191 (0.259) | 0.0541 (0.846) | 0.367 |
| Median [Min, Max] | -0.100 [-2.40, 2.10] | 0.200 [-0.500, 0.600] | 0.200 [-2.40, 2.10] | |
| SNR_manufacturerZ | ||||
| Mean (SD) | 0.000855 (1.00) | 0.191 (0.259) | 0.0600 (0.846) | 0.399 |
| Median [Min, Max] | 0.100 [-1.90, 2.30] | 0.200 [-0.500, 0.600] | 0.150 [-1.90, 2.30] |
SNR Stability Across Time
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Variation across quarters
Normalized Across Time
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Curate BULLET Phantom -
Full dataset
PRISMA |
SKYRA |
||||
|---|---|---|---|---|---|
| Outlier (N=9) |
Within Range (N=277) |
Outlier (N=3) |
Within Range (N=134) |
P-value | |
| Site | |||||
| Northeastern | 5 (55.6%) | 121 (43.7%) | 0 (0%) | 0 (0%) | <0.001 |
| Pittsburgh | 4 (44.4%) | 156 (56.3%) | 0 (0%) | 0 (0%) | |
| Kansas | 0 (0%) | 0 (0%) | 3 (100%) | 134 (100%) | |
| Year | |||||
| 2018 | 0 (0%) | 110 (39.7%) | 0 (0%) | 53 (39.6%) | 0.00224 |
| 2019 | 0 (0%) | 67 (24.2%) | 2 (66.7%) | 23 (17.2%) | |
| 2020 | 8 (88.9%) | 37 (13.4%) | 1 (33.3%) | 20 (14.9%) | |
| 2021 | 1 (11.1%) | 33 (11.9%) | 0 (0%) | 19 (14.2%) | |
| 2022 | 0 (0%) | 25 (9.0%) | 0 (0%) | 18 (13.4%) | |
| 2023-01-03 | 0 (0%) | 2 (0.7%) | 0 (0%) | 0 (0%) | |
| 2023-01-10 | 0 (0%) | 0 (0%) | 0 (0%) | 1 (0.7%) | |
| 2023-02-01 | 0 (0%) | 1 (0.4%) | 0 (0%) | 0 (0%) | |
| 2023-02-02 | 0 (0%) | 1 (0.4%) | 0 (0%) | 0 (0%) | |
| 2023-03-01 | 0 (0%) | 1 (0.4%) | 0 (0%) | 0 (0%) | |
| SNR | |||||
| Mean (SD) | 39.5 (5.66) | 99.0 (6.42) | 96.4 (60.6) | 101 (3.34) | <0.001 |
| Median [Min, Max] | 38.3 [31.8, 47.2] | 97.0 [86.7, 117] | 61.4 [61.4, 166] | 100 [88.5, 109] | |
| SNR_manufacturerZ | |||||
| Mean (SD) | -4.06 (0.413) | 0.174 (0.456) | -0.500 (6.58) | -0.0799 (0.369) | <0.001 |
| Median [Min, Max] | -4.20 [-4.60, -3.50] | 0 [-0.700, 1.50] | -4.30 [-4.30, 7.10] | -0.100 [-1.40, 0.900] | |
| SNR_siteZ | |||||
| Mean (SD) | -4.07 (0.283) | 0.172 (0.484) | -0.500 (6.58) | -0.0799 (0.369) | <0.001 |
| Median [Min, Max] | -4.10 [-4.50, -3.70] | 0.200 [-1.00, 1.40] | -4.30 [-4.30, 7.10] | -0.100 [-1.40, 0.900] | |
| SNR_scannerZ | |||||
| Mean (SD) | -4.07 (0.357) | 0.170 (0.487) | -0.500 (6.58) | -0.0799 (0.369) | <0.001 |
| Median [Min, Max] | -4.00 [-4.90, -3.70] | 0.200 [-1.10, 1.50] | -4.30 [-4.30, 7.10] | -0.100 [-1.40, 0.900] | |
| SpikeCount.ord.factor | |||||
| Low | 0 (0%) | 266 (96.0%) | 0 (0%) | 132 (98.5%) | <0.001 |
| Med | 0 (0%) | 9 (3.2%) | 0 (0%) | 2 (1.5%) | |
| High | 9 (100%) | 2 (0.7%) | 3 (100%) | 0 (0%) | |
| Kansas (N=137) |
Northeastern (N=126) |
Pittsburgh (N=160) |
P-value | |
|---|---|---|---|---|
| SpikeCount.ord.factor | ||||
| Low | 132 (96.4%) | 117 (92.9%) | 149 (93.1%) | 0.754 |
| Med | 2 (1.5%) | 4 (3.2%) | 5 (3.1%) | |
| High | 3 (2.2%) | 5 (4.0%) | 6 (3.8%) |
Exploratory Factor Analysis (PCA)
NO-SpikeCount
Dimension contribution across time-
Principal Componants across time
